Harvard Catalyst Profiles

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Jonathan Courtland Carlson, M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kuba W, Sohr B, Keppel P, Svatunek D, Humhal V, Stöger B, Goldeck M, Carlson JCT, Mikula H. Oxidative Desymmetrization Enables the Concise Synthesis of a trans-Cyclooctene Linker for Bioorthogonal Bond Cleavage. Chemistry. 2023 Jan 12; 29(3):e202203069. PMID: 36250260.
    Citations:    Fields:    
  2. Keppel P, Sohr B, Kuba W, Goldeck M, Skrinjar P, Carlson JCT, Mikula H. Tetrazine-Triggered Bioorthogonal Cleavage of trans-Cyclooctene-Caged Phenols Using a Minimal Self-Immolative Linker Strategy. Chembiochem. 2022 10 19; 23(20):e202200363. PMID: 35921044; PMCID: PMC9804162.
    Citations: 1     Fields:    Translation:Cells
  3. Foy BH, Sundt TM, Carlson JCT, Aguirre AD, Higgins JM. Human acute inflammatory recovery is defined by co-regulatory dynamics of white blood cell and platelet populations. Nat Commun. 2022 08 22; 13(1):4705. PMID: 35995789; PMCID: PMC9395541.
    Citations: 5     Fields:    Translation:HumansCells
  4. Ko J, Lucas K, Kohler R, Halabi EA, Wilkovitsch M, Carlson JCT, Weissleder R. In Vivo Click Chemistry Enables Multiplexed Intravital Microscopy. Adv Sci (Weinh). 2022 08; 9(24):e2200064. PMID: 35750648; PMCID: PMC9405492.
    Citations:    Fields:    
  5. Kim J, Oh J, Peterson HM, Carlson JCT, Pittet MJ, Weissleder R. TNIK Inhibition Has Dual Synergistic Effects on Tumor and Associated Immune Cells. Adv Biol (Weinh). 2022 Aug; 6(8):e2200030. PMID: 35675910; PMCID: PMC9398996.
    Citations:    Fields:    
  6. Oh J, Yoo TY, Saal TM, Tsay L, Faquin WC, Carlson JCT, Deschler DG, Pai SI, Weissleder R. Multiplexed single-cell analysis of FNA allows accurate diagnosis of salivary gland tumors. Cancer Cytopathol. 2022 08; 130(8):581-594. PMID: 35666645; PMCID: PMC9542730.
    Citations:    Fields:    
  7. Ko J, Wilkovitsch M, Oh J, Kohler RH, Bolli E, Pittet MJ, Vinegoni C, Sykes DB, Mikula H, Weissleder R, Carlson JCT. Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes. Nat Biotechnol. 2022 11; 40(11):1654-1662. PMID: 35654978; PMCID: PMC9669087.
    Citations:    Fields:    
  8. Peterson HM, Chin LK, Iwamoto Y, Oh J, Carlson JCT, Lee H, Im H, Weissleder R. Integrated Analytical System for Clinical Single-Cell Analysis. Adv Sci (Weinh). 2022 07; 9(20):e2200415. PMID: 35508767; PMCID: PMC9284190.
    Citations: 1     Fields:    Translation:Humans
  9. Ferguson S, Yang KS, Zelga P, Liss AS, Carlson JCT, Del Castillo CF, Weissleder R. Single-EV analysis (sEVA) of mutated proteins allows detection of stage 1 pancreatic cancer. Sci Adv. 2022 04 22; 8(16):eabm3453. PMID: 35452280; PMCID: PMC9032977.
    Citations:    Fields:    Translation:HumansCells
  10. Oh J, Carlson JCT, Landeros C, Lee H, Ferguson S, Faquin WC, Clark JR, Pittet MJ, Pai SI, Weissleder R. Rapid Serial Immunoprofiling of the Tumor Immune Microenvironment by Fine Needle Sampling. Clin Cancer Res. 2021 09 01; 27(17):4781-4793. PMID: 34233961; PMCID: PMC8416923.
    Citations: 5     Fields:    Translation:HumansAnimals
  11. Foy BH, Sundt T, Carlson JCT, Aguirre AD, Higgins JM. White Blood Cell and Platelet Dynamics Define Human Inflammatory Recovery. medRxiv. 2021 Jun 23. PMID: 34189534; PMCID: PMC8240689.
  12. Finn KM, Sutphin PD, Carlson JCT, Raskin KA, Van Cott EM. Case 17-2021: An 82-Year-Old Woman with Pain, Swelling, and Ecchymosis of the Left Arm. N Engl J Med. 2021 Jun 10; 384(23):2242-2250. PMID: 34107184.
    Citations:    Fields:    Translation:Humans
  13. Wilkovitsch M, Haider M, Sohr B, Herrmann B, Klubnick J, Weissleder R, Carlson JCT, Mikula H. A Cleavable C2-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes. J Am Chem Soc. 2020 11 11; 142(45):19132-19141. PMID: 33119297.
    Citations: 9     Fields:    Translation:Cells
  14. Foy BH, Carlson JCT, Reinertsen E, Padros I Valls R, Pallares Lopez R, Palanques-Tost E, Mow C, Westover MB, Aguirre AD, Higgins JM. Association of Red Blood Cell Distribution Width With Mortality Risk in Hospitalized Adults With SARS-CoV-2 Infection. JAMA Netw Open. 2020 09 01; 3(9):e2022058. PMID: 32965501.
    Citations: 76     Fields:    Translation:HumansCellsPHPublic Health
  15. Al-Samkari H, Karp Leaf RS, Dzik WH, Carlson JCT, Fogerty AE, Waheed A, Goodarzi K, Bendapudi PK, Bornikova L, Gupta S, Leaf DE, Kuter DJ, Rosovsky RP. COVID-19 and coagulation: bleeding and thrombotic manifestations of SARS-CoV-2 infection. Blood. 2020 07 23; 136(4):489-500. PMID: 32492712; PMCID: PMC7378457.
    Citations: 447     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
  16. Marquard AN, Carlson JCT, Weissleder R. Expanding the Scope of Antibody Rebridging with New Pyridazinedione-TCO Constructs. Bioconjug Chem. 2020 06 17; 31(6):1616-1623. PMID: 32286045.
    Citations: 1     Fields:    Translation:HumansAnimals
  17. Ko J, Wang Y, Carlson JCT, Marquard A, Gungabeesoon J, Charest A, Weitz D, Pittet MJ, Weissleder R. Single Extracellular Vesicle Protein Analysis Using Immuno-Droplet Digital Polymerase Chain Reaction Amplification. Adv Biosyst. 2020 12; 4(12):e1900307. PMID: 33274611.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  18. Ko J, Oh J, Ahmed MS, Carlson JCT, Weissleder R. Ultra-fast Cycling for Multiplexed Cellular Fluorescence Imaging. Angew Chem Int Ed Engl. 2020 04 20; 59(17):6839-6846. PMID: 32004403.
    Citations: 12     Fields:    Translation:HumansCells
  19. Ko J, Oh J, Ahmed MS, Carlson JCT, Weissleder R. Ultra-fast cycling for multiplexed cellular fluorescence imaging. Angew Chem Weinheim Bergstr Ger. 2020 Apr 20; 132(17):6906-6913. PMID: 34366494.
    Citations: 1     
  20. Marquard AN, Carlson JCT, Weissleder R. Glass Chemistry to Analyze Human Cells under Adverse Conditions. ACS Omega. 2019 Jul 31; 4(7):11515-11521. PMID: 31460257; PMCID: PMC6682085.
    Citations: 1     
  21. Carlson JCT, Hogan C, Ivkovic A. Case 5-2019: A Woman with Delusional Thinking and Paresthesia of the Right Hand. Reply. N Engl J Med. 2019 05 23; 380(21):2082. PMID: 31116941.
    Citations:    Fields:    Translation:Humans
  22. Hogan C, Little BP, Carlson JCT, Freudenreich O, Ivkovic A, Baron JM. Case 5-2019: A 48-Year-Old Woman with Delusional Thinking and Paresthesia of the Right Hand. N Engl J Med. 2019 Feb 14; 380(7):665-674. PMID: 30763197.
    Citations:    Fields:    Translation:Humans
  23. Giedt RJ, Pathania D, Carlson JCT, McFarland PJ, Del Castillo AF, Juric D, Weissleder R. Single-cell barcode analysis provides a rapid readout of cellular signaling pathways in clinical specimens. Nat Commun. 2018 10 31; 9(1):4550. PMID: 30382095.
    Citations: 25     Fields:    Translation:HumansCells
  24. Carlson JCT, Mikula H, Weissleder R. Unraveling Tetrazine-Triggered Bioorthogonal Elimination Enables Chemical Tools for Ultrafast Release and Universal Cleavage. J Am Chem Soc. 2018 03 14; 140(10):3603-3612. PMID: 29384666.
    Citations: 38     Fields:    Translation:Cells
  25. Arlauckas SP, Garris CS, Kohler RH, Kitaoka M, Cuccarese MF, Yang KS, Miller MA, Carlson JC, Freeman GJ, Anthony RM, Weissleder R, Pittet MJ. In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy. Sci Transl Med. 2017 05 10; 9(389). PMID: 28490665; PMCID: PMC5734617.
    Citations: 230     Fields:    Translation:HumansAnimalsCells
  26. Meimetis LG, Giedt RJ, Mikula H, Carlson JC, Kohler RH, Pirovich DB, Weissleder R. Fluorescent vinblastine probes for live cell imaging. Chem Commun (Camb). 2016 Aug 02; 52(64):9953-6. PMID: 27439765; PMCID: PMC4970878.
    Citations: 4     Fields:    Translation:HumansCells
  27. Meimetis LG, Boros E, Carlson JC, Ran C, Caravan P, Weissleder R. Bioorthogonal Fluorophore Linked DFO-Technology Enabling Facile Chelator Quantification and Multimodal Imaging of Antibodies. Bioconjug Chem. 2016 Jan 20; 27(1):257-63. PMID: 26684717; PMCID: PMC4858350.
    Citations: 18     Fields:    Translation:HumansAnimals
  28. Hong S, Carlson J, Lee H, Weissleder R. Bioorthogonal Radiopaque Hydrogel for Endoscopic Delivery and Universal Tissue Marking. Adv Healthc Mater. 2016 Feb 18; 5(4):421-6. PMID: 26688173.
    Citations: 7     Fields:    Translation:AnimalsCells
  29. Meimetis LG, Carlson JC, Giedt RJ, Kohler RH, Weissleder R. Ultrafluorogenic coumarin-tetrazine probes for real-time biological imaging. Angew Chem Int Ed Engl. 2014 Jul 14; 53(29):7531-4. PMID: 24915832.
    Citations: 54     Fields:    Translation:Cells
  30. Carlson JC, Meimetis LG, Hilderbrand SA, Weissleder R. BODIPY-tetrazine derivatives as superbright bioorthogonal turn-on probes. Angew Chem Int Ed Engl. 2013 Jul 01; 52(27):6917-20. PMID: 23712730.
    Citations: 66     Fields:    Translation:Cells
  31. White BR, Carlson JC, Kerns JL, Wagner CR. Protein interface remodeling in a chemically induced protein dimer. J Mol Recognit. 2012 Jul; 25(7):393-403. PMID: 22733548.
    Citations:    Fields:    Translation:Cells
  32. Fegan A, White B, Carlson JC, Wagner CR. Chemically controlled protein assembly: techniques and applications. Chem Rev. 2010 Jun 09; 110(6):3315-36. PMID: 20353181.
    Citations: 101     Fields:    Translation:Cells
  33. Chou TF, So C, White BR, Carlson JC, Sarikaya M, Wagner CR. Enzyme nanorings. ACS Nano. 2008 Dec 23; 2(12):2519-25. PMID: 19206287.
    Citations: 8     Fields:    
  34. Carlson JC, Jena SS, Flenniken M, Chou TF, Siegel RA, Wagner CR. Chemically controlled self-assembly of protein nanorings. J Am Chem Soc. 2006 Jun 14; 128(23):7630-8. PMID: 16756320.
    Citations: 27     Fields:    Translation:Cells
  35. Carlson JC, Kanter A, Thuduppathy GR, Cody V, Pineda PE, McIvor RS, Wagner CR. Designing protein dimerizers: the importance of ligand conformational equilibria. J Am Chem Soc. 2003 Feb 12; 125(6):1501-7. PMID: 12568609.
    Citations: 10     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.