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Jonathan Lewis Hecht, Ph.D., M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Burris HH, Just AC, Haviland MJ, Neo DT, Baccarelli AA, Dereix AE, Brennan KJ, Rodosthenous RS, Ralston SJ, Hecht JL, Hacker MR. Long noncoding RNA expression in the cervix mid-pregnancy is associated with the length of gestation at delivery. Epigenetics. 2018 Aug 10; 1-9. PMID: 30045669.
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  2. Barnard ME, Pyden A, Rice MS, Linares M, Tworoger SS, Howitt BE, Meserve EE, Hecht JL. Inter-pathologist and pathology report agreement for ovarian tumor characteristics in the Nurses' Health Studies. Gynecol Oncol. 2018 Jul 09. PMID: 30001835.
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  3. Ditzel HM, Strickland KC, Meserve EE, Stover E, Konstantinopoulos PA, Matulonis UA, Muto MG, Liu JF, Feltmate C, Horowitz N, Berkowitz RS, Gupta M, Hecht JL, Lin DI, Jochumsen KM, Welch WR, Hirsch MS, Quade BJ, Lee KR, Crum CP, Mutter GL, Nucci MR, Howitt BE. Assessment of a Chemotherapy Response Score (CRS) System for Tubo-Ovarian High-Grade Serous Carcinoma (HGSC). Int J Gynecol Pathol. 2018 May 10. PMID: 29750700.
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  4. Martinot AJ, Abbink P, Afacan O, Prohl AK, Bronson R, Hecht JL, Borducchi EN, Larocca RA, Peterson RL, Rinaldi W, Ferguson M, Didier PJ, Weiss D, Lewis MG, De La Barrera RA, Yang E, Warfield SK, Barouch DH. Fetal Neuropathology in Zika Virus-Infected Pregnant Female Rhesus Monkeys. Cell. 2018 May 17; 173(5):1111-1122.e10. PMID: 29606355.
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  5. Buitrago DH, Pinto D, Berkowitz SJ, Laham RJ, Hecht JL, Kent MS. Fatal Hemoptysis After Closure of Gastrobronchial Fistula Using an Amplatzer Vascular Device. Ann Thorac Surg. 2018 Feb; 105(2):e71-e73. PMID: 29362196.
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  6. Fadare O, Roma AA, Desouki MM, Gwin K, Hanley KZ, Jarboe EA, Liang SX, Quick CM, Zheng W, Hecht JL, Parkash V, Wang XJ. The significance of L1CAM expression in clear cell carcinoma of the endometrium. Histopathology. 2018 02; 72(3):532-538. PMID: 28941294.
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  7. Fadare O, Desouki MM, Gwin K, Hanley KZ, Jarboe EA, Liang SX, Quick CM, Rawish KR, Roma AA, Zheng W, Hecht JL, Parkash V, Osunkoya AO. Clear Cell Renal Cell Carcinoma Metastatic to the Gynecologic Tract: A Clinicopathologic Analysis of 17 Cases. Int J Gynecol Pathol. 2017 Nov 14. PMID: 29140878.
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  8. Harris HR, Rice MS, Shafrir AL, Poole EM, Gupta M, Hecht JL, Terry KL, Tworoger SS. Lifestyle and Reproductive Factors and Ovarian Cancer Risk by p53 and MAPK Expression. Cancer Epidemiol Biomarkers Prev. 2018 Jan; 27(1):96-102. PMID: 29133366.
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  9. Hecht JL, Ordi J, Carrilho C, Ismail MR, Zsengeller ZK, Karumanchi SA, Rosen S. The pathology of eclampsia: An autopsy series. Hypertens Pregnancy. 2017 Aug; 36(3):259-268. PMID: 28678644.
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  10. Shainker SA, Dannheim K, Gerson KD, Neo D, Zsengeller ZK, Pernicone E, Karumanchi SA, Hacker MR, Hecht JL. Down-regulation of soluble fms-like tyrosine kinase 1 expression in invasive placentation. Arch Gynecol Obstet. 2017 Aug; 296(2):257-262. PMID: 28631072.
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  11. Hu J, Lu J, Goyal A, Wong T, Lian G, Zhang J, Hecht JL, Feng Y, Sheen VL. Opposing FlnA and FlnB interactions regulate RhoA activation in guiding dynamic actin stress fiber formation and cell spreading. Hum Mol Genet. 2017 04 01; 26(7):1294-1304. PMID: 28175289.
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  12. Spiel M, Salahuddin S, Pernicone E, Zsengeller Z, Wang A, Modest AM, Karumanchi SA, Hecht JL. Placental soluble fms-like tyrosine kinase expression in small for gestational age infants and risk for adverse outcomes. Placenta. 2017 Apr; 52:10-16. PMID: 28454690.
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  13. Shafrir AL, Rice MS, Gupta M, Terry KL, Rosner BA, Tamimi RM, Hecht JL, Tworoger SS. The association between reproductive and hormonal factors and ovarian cancer by estrogen-a and progesterone receptor status. Gynecol Oncol. 2016 Dec; 143(3):628-635. PMID: 27720231.
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  14. Huang T, Tworoger SS, Hecht JL, Rice MS, Sood AK, Kubzansky LD, Poole EM. Association of Ovarian Tumor ß2-Adrenergic Receptor Status with Ovarian Cancer Risk Factors and Survival. Cancer Epidemiol Biomarkers Prev. 2016 12; 25(12):1587-1594. PMID: 27587791.
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  15. Hecht JL, Zsengeller ZK, Spiel M, Karumanchi SA, Rosen S. Revisiting decidual vasculopathy. Placenta. 2016 Jun; 42:37-43. PMID: 27238712.
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  16. Lu J, Mccarter M, Lian G, Esposito G, Capoccia E, Delli-Bovi LC, Hecht J, Sheen V. Global hypermethylation in fetal cortex of Down syndrome due to DNMT3L overexpression. Hum Mol Genet. 2016 05 01; 25(9):1714-27. PMID: 26911678; PMCID: PMC4986328 [Available on 05/01/17].
  17. Lin DI, Hecht JL. Targeted Screening With Combined Age- and Morphology-Based Criteria Enriches Detection of Lynch Syndrome in Endometrial Cancer. Int J Surg Pathol. 2016 Jun; 24(4):297-305. PMID: 26842347.
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  18. Dannheim K, Shainker SA, Hecht JL. Hysterectomy for placenta accreta; methods for gross and microscopic pathology examination. Arch Gynecol Obstet. 2016 May; 293(5):951-8. PMID: 26758078.
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  19. Wang A, Zsengellér ZK, Hecht JL, Buccafusca R, Burke SD, Rajakumar A, Weingart E, Yu PB, Salahuddin S, Karumanchi SA. Excess placental secreted frizzled-related protein 1 in maternal smokers impairs fetal growth. J Clin Invest. 2015 Nov 02; 125(11):4021-5. PMID: 26413870; PMCID: PMC4639969.
  20. Fata CR, Seeley EH, Desouki MM, Du L, Gwin K, Hanley KZ, Hecht JL, Jarboe EA, Liang SX, Parkash V, Quick CM, Zheng W, Shyr Y, Caprioli RM, Fadare O. Are clear cell carcinomas of the ovary and endometrium phenotypically identical? A proteomic analysis. Hum Pathol. 2015 Oct; 46(10):1427-36. PMID: 26243671.
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  21. Johnson MB, Wang PP, Atabay KD, Murphy EA, Doan RN, Hecht JL, Walsh CA. Single-cell analysis reveals transcriptional heterogeneity of neural progenitors in human cortex. Nat Neurosci. 2015 May; 18(5):637-46. PMID: 25734491.
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  22. Baltajian K, Hecht JL, Wenger JB, Salahuddin S, Verlohren S, Perschel FH, Zsengeller ZK, Thadhani R, Ananth Karumanchi S, Rana S. [56-OR]: Placental lesions of vascular insufficiency are associated with anti-angiogenic state in women with preeclampsia. Pregnancy Hypertens. 2015 Jan; 5(1):28-9. PMID: 25787406.
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  23. Downey LC, O'Shea TM, Allred EN, Kuban K, McElrath TF, Warner DD, Ware J, Hecht JL, Onderdonk A, Leviton A. Antenatal and early postnatal antecedents of parent-reported attention problems at 2 years of age. J Pediatr. 2015 Jan; 166(1):20-5. PMID: 25241173.
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  24. Baltajian K, Hecht JL, Wenger JB, Salahuddin S, Verlohren S, Perschel FH, Zsengeller ZK, Thadhani R, Karumanchi SA, Rana S. Placental lesions of vascular insufficiency are associated with anti-angiogenic state in women with preeclampsia. Hypertens Pregnancy. 2014 Nov; 33(4):427-39. PMID: 25062083.
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  25. Litt JS, Hecht JL. Placental pathology and neonatal thrombocytopenia: lesion type is associated with increased risk. J Perinatol. 2014 Dec; 34(12):914-6. PMID: 24945163.
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  26. Hecht JL, Konstantinopoulos PA, Awtrey CS, Soslow RA. Immunohistochemical loss of BRCA1 protein in uterine serous carcinoma. Int J Gynecol Pathol. 2014 May; 33(3):282-7. PMID: 24681740.
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  27. Hu J, Lu J, Lian G, Zhang J, Hecht JL, Sheen VL. Filamin B regulates chondrocyte proliferation and differentiation through Cdk1 signaling. PLoS One. 2014; 9(2):e89352. PMID: 24551245; PMCID: PMC3925234.
  28. Fadare O, Desouki MM, Gwin K, Hanley KZ, Jarboe EA, Liang SX, Quick CM, Zheng W, Parkash V, Hecht JL. Frequent expression of napsin A in clear cell carcinoma of the endometrium: potential diagnostic utility. Am J Surg Pathol. 2014 Feb; 38(2):189-96. PMID: 24145649.
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  29. Fadare O, Parkash V, Gwin K, Hanley KZ, Jarboe EA, Liang SX, Quick CM, Zheng W, Rawish KR, Hecht JL, Desouki MM. Utility of a-methylacyl-coenzyme-A racemase (p504s) immunohistochemistry in distinguishing endometrial clear cell carcinomas from serous and endometrioid carcinomas. Hum Pathol. 2013 Dec; 44(12):2814-21. PMID: 24119561; PMCID: PMC3865867.
  30. Schmolze D, Awtrey CS, Hecht JL. Value of additional level sections in the evaluation of lymph nodes for endometrial carcinoma staging. Am J Clin Pathol. 2013 Oct; 140(4):516-8. PMID: 24045548.
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  31. Siedler A, Hecht J, Rieck T, Tolksdorf K, Hengel H. [Varicella vaccination in Germany. A provisional appraisal in the context of MMR vaccination]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2013 Sep; 56(9):1313-20. PMID: 23990095.
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  32. Howitt BE, Herfs M, Brister K, Oliva E, Longtine J, Hecht JL, Nucci MR. Intestinal-type endocervical adenocarcinoma in situ: an immunophenotypically distinct subset of AIS affecting older women. Am J Surg Pathol. 2013 May; 37(5):625-33. PMID: 23552379.
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  33. Fadare O, Gwin K, Desouki MM, Crispens MA, Jones HW, Khabele D, Liang SX, Zheng W, Mohammed K, Hecht JL, Parkash V. The clinicopathologic significance of p53 and BAF-250a (ARID1A) expression in clear cell carcinoma of the endometrium. Mod Pathol. 2013 Aug; 26(8):1101-10. PMID: 23524907; PMCID: PMC3886836.
  34. Kotsopoulos J, Terry KL, Poole EM, Rosner B, Murphy MA, Hecht JL, Crum CP, Missmer SA, Cramer DW, Tworoger SS. Ovarian cancer risk factors by tumor dominance, a surrogate for cell of origin. Int J Cancer. 2013 Aug 01; 133(3):730-9. PMID: 23364849; PMCID: PMC3690361.
  35. Fadare O, Liang SX, Crispens MA, Jones HW, Khabele D, Gwin K, Zheng W, Mohammed K, Parkash V, Hecht JL, Desouki MM. Expression of the oncofetal protein IGF2BP3 in endometrial clear cell carcinoma: assessment of frequency and significance. Hum Pathol. 2013 Aug; 44(8):1508-15. PMID: 23465280; PMCID: PMC3888088.
  36. Fadare O, Zheng W, Crispens MA, Jones HW, Khabele D, Gwin K, Liang SX, Mohammed K, Desouki MM, Parkash V, Hecht JL. Morphologic and other clinicopathologic features of endometrial clear cell carcinoma: a comprehensive analysis of 50 rigorously classified cases. Am J Cancer Res. 2013; 3(1):70-95. PMID: 23359866; PMCID: PMC3555196.
  37. Fadare O, Parkash V, Dupont WD, Acs G, Atkins KA, Irving JA, Pirog EC, Quade BJ, Quddus MR, Rabban JT, Vang R, Hecht JL. The diagnosis of endometrial carcinomas with clear cells by gynecologic pathologists: an assessment of interobserver variability and associated morphologic features. Am J Surg Pathol. 2012 Aug; 36(8):1107-18. PMID: 22790851.
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  38. Kane SE, Hecht JL. Endometrial intraepithelial neoplasia terminology in practice: 4-year experience at a single institution. Int J Gynecol Pathol. 2012 Mar; 31(2):160-165. PMID: 22317874.
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  39. Lu J, Lian G, Zhou H, Esposito G, Steardo L, Delli-Bovi LC, Hecht JL, Lu QR, Sheen V. OLIG2 over-expression impairs proliferation of human Down syndrome neural progenitors. Hum Mol Genet. 2012 May 15; 21(10):2330-40. PMID: 22343408; PMCID: PMC3335315.
  40. Helderman JB, O'Shea TM, Kuban KC, Allred EN, Hecht JL, Dammann O, Paneth N, McElrath TF, Onderdonk A, Leviton A. Antenatal antecedents of cognitive impairment at 24 months in extremely low gestational age newborns. Pediatrics. 2012 Mar; 129(3):494-502. PMID: 22331342; PMCID: PMC3289523.
  41. Selby KJ, Warner J, Klempner S, Konstantinopoulos PA, Hecht JL. Anti-Yo antibody associated with occult fallopian tube carcinoma. Int J Gynecol Pathol. 2011 Nov; 30(6):536-8. PMID: 21979588.
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  42. Chen ML, Allred EN, Hecht JL, Onderdonk A, VanderVeen D, Wallace DK, Leviton A, Dammann O. Placenta microbiology and histology and the risk for severe retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2011 Sep 01; 52(10):7052-8. PMID: 21775664; PMCID: PMC3207711.
  43. Lu J, Esposito G, Scuderi C, Steardo L, Delli-Bovi LC, Hecht JL, Dickinson BC, Chang CJ, Mori T, Sheen V. S100B and APP promote a gliocentric shift and impaired neurogenesis in Down syndrome neural progenitors. PLoS One. 2011; 6(7):e22126. PMID: 21779383; PMCID: PMC3133657.
  44. Leviton A, Hecht JL, Allred EN, Yamamoto H, Fichorova RN, Dammann O. Persistence after birth of systemic inflammation associated with umbilical cord inflammation. J Reprod Immunol. 2011 Aug; 90(2):235-43. PMID: 21722967.
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  45. Karst AM, Levanon K, Duraisamy S, Liu JF, Hirsch MS, Hecht JL, Drapkin R. Stathmin 1, a marker of PI3K pathway activation and regulator of microtubule dynamics, is expressed in early pelvic serous carcinomas. Gynecol Oncol. 2011 Oct; 123(1):5-12. PMID: 21683992; PMCID: PMC3171572.
  46. Konstantinopoulos PA, Spentzos D, Fountzilas E, Francoeur N, Sanisetty S, Grammatikos AP, Hecht JL, Cannistra SA. Keap1 mutations and Nrf2 pathway activation in epithelial ovarian cancer. Cancer Res. 2011 Aug 01; 71(15):5081-9. PMID: 21676886.
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  47. Faupel-Badger JM, Fichorova RN, Allred EN, Hecht JL, Dammann O, Leviton A, McElrath TF. Cluster analysis of placental inflammatory proteins can distinguish preeclampsia from preterm labor and premature membrane rupture in singleton deliveries less than 28 weeks of gestation. Am J Reprod Immunol. 2011 Dec; 66(6):488-94. PMID: 21623999.
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  48. Lu J, Delli-Bovi LC, Hecht J, Folkerth R, Sheen VL. Generation of neural stem cells from discarded human fetal cortical tissue. J Vis Exp. 2011 May 25; (51). PMID: 21654623; PMCID: PMC3197109.
  49. Marotti JD, Glatz K, Parkash V, Hecht JL. International Internet-based assessment of observer variability for diagnostically challenging endometrial biopsies. Arch Pathol Lab Med. 2011 Apr; 135(4):464-70. PMID: 21466363.
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  50. Hecht JL. To count and how to count, that is the question. Am J Clin Pathol. 2011 Mar; 135(3):480. PMID: 21350105.
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  51. McElrath TF, Fichorova RN, Allred EN, Hecht JL, Ismail MA, Yuan H, Leviton A. Blood protein profiles of infants born before 28 weeks differ by pregnancy complication. Am J Obstet Gynecol. 2011 May; 204(5):418.e1-418.e12. PMID: 21349490.
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  52. Hecht JL, Fichorova RN, Tang VF, Allred EN, McElrath TF, Leviton A. Relationship Between Neonatal Blood Protein Concentrations and Placenta Histologic Characteristics in Extremely Low GA Newborns. Pediatr Res. 2011 Jan; 69(1):68-73. PMID: 20921924; PMCID: PMC3066075.
  53. Stewart GC, Lopez-Molina J, Gottumukkala RV, Rosner GF, Anello MS, Hecht JL, Winters GL, Padera RF, Baughman KL, Lipes MA. Myocardial parvovirus B19 persistence: lack of association with clinicopathologic phenotype in adults with heart failure. Circ Heart Fail. 2011 Jan; 4(1):71-8. PMID: 21097605; PMCID: PMC3047418.
  54. Leviton A, Fichorova R, Yamamoto Y, Allred EN, Dammann O, Hecht J, Kuban K, McElrath T, O'Shea TM, Paneth N. Inflammation-related proteins in the blood of extremely low gestational age newborns. The contribution of inflammation to the appearance of developmental regulation. Cytokine. 2011 Jan; 53(1):66-73. PMID: 20934883; PMCID: PMC2987520.
  55. Levine D, Brown DL, Andreotti RF, Benacerraf B, Benson CB, Brewster WR, Coleman B, DePriest P, Doubilet PM, Goldstein SR, Hamper UM, Hecht JL, Horrow M, Hur HC, Marnach M, Patel MD, Platt LD, Puscheck E, Smith-Bindman R. Management of asymptomatic ovarian and other adnexal cysts imaged at US Society of Radiologists in Ultrasound consensus conference statement. Ultrasound Q. 2010 Sep; 26(3):121-31. PMID: 20823748.
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  56. West DS, Gorin AA, Subak LL, Foster G, Bragg C, Hecht J, Schembri M, Wing RR. A motivation-focused weight loss maintenance program is an effective alternative to a skill-based approach. Int J Obes (Lond). 2011 Feb; 35(2):259-69. PMID: 20680012; PMCID: PMC2974962.
  57. Leviton A, Kuban K, Allred EN, Hecht JL, Onderdonk A, O'Shea TM, McElrath T, Paneth N. Antenatal antecedents of a small head circumference at age 24-months post-term equivalent in a sample of infants born before the 28th post-menstrual week. Early Hum Dev. 2010 Aug; 86(8):515-21. PMID: 20674197; PMCID: PMC2967731.
  58. McElrath TF, Allred EN, Kuban K, Hecht JL, Onderdonk A, O'Shea TM, Paneth N, Leviton A. Factors associated with small head circumference at birth among infants born before the 28th week. Am J Obstet Gynecol. 2010 Aug; 203(2):138.e1-8. PMID: 20541727; PMCID: PMC2989671.
  59. Levine D, Brown DL, Andreotti RF, Benacerraf B, Benson CB, Brewster WR, Coleman B, Depriest P, Doubilet PM, Goldstein SR, Hamper UM, Hecht JL, Horrow M, Hur HC, Marnach M, Patel MD, Platt LD, Puscheck E, Smith-Bindman R. Management of asymptomatic ovarian and other adnexal cysts imaged at US: Society of Radiologists in Ultrasound Consensus Conference Statement. Radiology. 2010 Sep; 256(3):943-54. PMID: 20505067.
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  60. Kotsopoulos J, Hecht JL, Marotti JD, Kelemen LE, Tworoger SS. Relationship between dietary and supplemental intake of folate, methionine, vitamin B6 and folate receptor alpha expression in ovarian tumors. Int J Cancer. 2010 May 01; 126(9):2191-8. PMID: 19585555; PMCID: PMC2848529.
  61. Chan MP, Hecht JL, Kane SE. Incidence and clinicopathologic correlation of fetal vessel thrombosis in mono- and dichorionic twin placentas. J Perinatol. 2010 Oct; 30(10):660-4. PMID: 20200539.
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  62. Leviton A, Allred EN, Kuban KC, Hecht JL, Onderdonk AB, O'shea TM, Paneth N. Microbiologic and histologic characteristics of the extremely preterm infant's placenta predict white matter damage and later cerebral palsy. the ELGAN study. Pediatr Res. 2010 Jan; 67(1):95-101. PMID: 19745780; PMCID: PMC2794973.
  63. Gates MA, Rosner BA, Hecht JL, Tworoger SS. Risk factors for epithelial ovarian cancer by histologic subtype. Am J Epidemiol. 2010 Jan 01; 171(1):45-53. PMID: 19910378; PMCID: PMC2796984.
  64. McElrath TF, Hecht JL. Invited commentary: Intrauterine epidemiology. Am J Epidemiol. 2009 Jul 15; 170(2):159-61; discussion 162-3. PMID: 19509319.
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  65. Sharma S, Reid T, Hoosen S, Garrett C, Beck J, Davidson S, MacKenzie M, Brandt U, Hecht J. Phase I study of RAD001 (everolimus), cetuximab, and irinotecan as second-line therapy in metastatic colorectal cancer (mCRC). J Clin Oncol. 2009 May 20; 27(15_suppl):e15115. PMID: 27960849.
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  66. Olomu IN, Hecht JL, Onderdonk AO, Allred EN, Leviton A. Perinatal correlates of Ureaplasma urealyticum in placenta parenchyma of singleton pregnancies that end before 28 weeks of gestation. Pediatrics. 2009 May; 123(5):1329-36. PMID: 19403499; PMCID: PMC2824163.
  67. Hecht JL, Kotsopoulos J, Hankinson SE, Tworoger SS. Relationship between epidemiologic risk factors and hormone receptor expression in ovarian cancer: results from the Nurses' Health Study. Cancer Epidemiol Biomarkers Prev. 2009 May; 18(5):1624-30. PMID: 19383883; PMCID: PMC2814542.
  68. Asch E, Levine D, Pedrosa I, Hecht JL, Kruskal J. Patterns of misinterpretation of adnexal masses on CT and MR in an academic radiology department. Acad Radiol. 2009 Aug; 16(8):969-80. PMID: 19380241.
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  69. Hecht JL, Dolinski BM, Gardner HA, Violette SM, Weinreb PH. Overexpression of the alphavbeta6 integrin in endometrial cancer. Appl Immunohistochem Mol Morphol. 2008 Dec; 16(6):543-7. PMID: 18698261.
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  70. Ferland RJ, Batiz LF, Neal J, Lian G, Bundock E, Lu J, Hsiao YC, Diamond R, Mei D, Banham AH, Brown PJ, Vanderburg CR, Joseph J, Hecht JL, Folkerth R, Guerrini R, Walsh CA, Rodriguez EM, Sheen VL. Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia. Hum Mol Genet. 2009 Feb 01; 18(3):497-516. PMID: 18996916; PMCID: PMC2722192.
  71. Hecht JL, Kotsopoulos J, Gates MA, Hankinson SE, Tworoger SS. Validation of tissue microarray technology in ovarian cancer: results from the Nurses' Health Study. Cancer Epidemiol Biomarkers Prev. 2008 Nov; 17(11):3043-50. PMID: 18990746; PMCID: PMC2628443.
  72. Fadare O, Orejudos MP, Jain R, Mariappan MR, Hecht JL, Renshaw IL, Hileeto D, Wang SA, Ghofrani M, Liang SX. A comparative analysis of lymphatic vessel density in ovarian serous tumors of low malignant potential (borderline tumors) with and without lymph node involvement. Int J Gynecol Pathol. 2008 Oct; 27(4):483-90. PMID: 18753975.
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  73. McElrath TF, Hecht JL, Dammann O, Boggess K, Onderdonk A, Markenson G, Harper M, Delpapa E, Allred EN, Leviton A. Pregnancy disorders that lead to delivery before the 28th week of gestation: an epidemiologic approach to classification. Am J Epidemiol. 2008 Nov 01; 168(9):980-9. PMID: 18756014; PMCID: PMC2720771.
  74. Hecht JL, Allred EN, Kliman HJ, Zambrano E, Doss BJ, Husain A, Pflueger SM, Chang CH, Livasy CA, Roberts D, Bhan I, Ross DW, Senagore PK, Leviton A. Histological characteristics of singleton placentas delivered before the 28th week of gestation. Pathology. 2008 Jun; 40(4):372-6. PMID: 18446627; PMCID: PMC2990223.
  75. Levine D, Asch E, Mehta TS, Broder J, O'Donnell C, Hecht JL. Assessment of factors that affect the quality of performance and interpretation of sonography of adnexal masses. J Ultrasound Med. 2008 May; 27(5):721-8. PMID: 18424647.
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  76. Onderdonk AB, Hecht JL, McElrath TF, Delaney ML, Allred EN, Leviton A. Colonization of second-trimester placenta parenchyma. Am J Obstet Gynecol. 2008 Jul; 199(1):52.e1-52.e10. PMID: 18313635; PMCID: PMC2827873.
  77. Asch E, Levine D, Kim Y, Hecht JL. Histologic, surgical, and imaging correlations of adnexal masses. J Ultrasound Med. 2008 Mar; 27(3):327-42. PMID: 18314510.
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  78. Tworoger SS, Gertig DM, Gates MA, Hecht JL, Hankinson SE. Caffeine, alcohol, smoking, and the risk of incident epithelial ovarian cancer. Cancer. 2008 Mar 01; 112(5):1169-77. PMID: 18213613.
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  79. Hecht JL, Onderdonk A, Delaney M, Allred EN, Kliman HJ, Zambrano E, Pflueger SM, Livasy CA, Bhan I, Leviton A. Characterization of chorioamnionitis in 2nd-trimester C-section placentas and correlation with microorganism recovery from subamniotic tissues. Pediatr Dev Pathol. 2008 Jan-Feb; 11(1):15-22. PMID: 18237241.
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  80. Baumann CR, Clark EL, Pedersen NP, Hecht JL, Scammell TE. Do enteric neurons make hypocretin? Regul Pept. 2008 Apr 10; 147(1-3):1-3. PMID: 18191238; PMCID: PMC2276606.
  81. Gates MA, Tworoger SS, Hecht JL, De Vivo I, Rosner B, Hankinson SE. A prospective study of dietary flavonoid intake and incidence of epithelial ovarian cancer. Int J Cancer. 2007 Nov 15; 121(10):2225-32. PMID: 17471564.
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  82. Esposito G, Imitola J, Lu J, De Filippis D, Scuderi C, Ganesh VS, Folkerth R, Hecht J, Shin S, Iuvone T, Chesnut J, Steardo L, Sheen V. Genomic and functional profiling of human Down syndrome neural progenitors implicates S100B and aquaporin 4 in cell injury. Hum Mol Genet. 2008 Feb 01; 17(3):440-57. PMID: 17984171.
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  83. Hanley LC, Boyd TK, Hecht JL. Acardiac twin presenting as fetus amorphous with an attenuated umbilical cord. Pediatr Dev Pathol. 2007 Nov-Dec; 10(6):487-90. PMID: 18001161.
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  84. Chan M, Hecht JL, Boyd T, Rosen S. Congenital cytomegalovirus infection: a cause of renal dysplasia? Pediatr Dev Pathol. 2007 Jul-Aug; 10(4):300-4. PMID: 17638423.
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  85. Hecht JL, Kliman HJ, Allred EN, Pflueger SM, Chang CH, Doss BJ, Roberts D, Livasy CA, Bhan I, Zambrano E, Ross DW, Senagore P, Husain AN, Leviton A. Reference weights for placentas delivered before the 28th week of gestation. Placenta. 2007 Oct; 28(10):987-90. PMID: 17573110.
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  86. Danforth KN, Tworoger SS, Hecht JL, Rosner BA, Colditz GA, Hankinson SE. Breastfeeding and risk of ovarian cancer in two prospective cohorts. Cancer Causes Control. 2007 Jun; 18(5):517-23. PMID: 17450440.
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  87. Gilmore H, Fleischhacker D, Hecht JL. Diagnosis of chronic endometritis in biopsies with stromal breakdown. Hum Pathol. 2007 Apr; 38(4):581-4. PMID: 17188330.
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  88. Danforth KN, Tworoger SS, Hecht JL, Rosner BA, Colditz GA, Hankinson SE. A prospective study of postmenopausal hormone use and ovarian cancer risk. Br J Cancer. 2007 Jan 15; 96(1):151-6. PMID: 17179984; PMCID: PMC2360221.
  89. Galan M, Kim YB, Hecht JL. Does physiologic breakdown mask significant pathology in endometrial biopsies? A retrospective case-control study. Arch Pathol Lab Med. 2006 Dec; 130(12):1847-9. PMID: 17149962.
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  90. Hecht JL, Mutter GL. Molecular and pathologic aspects of endometrial carcinogenesis. J Clin Oncol. 2006 Oct 10; 24(29):4783-91. PMID: 17028294.
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  91. Sheen VL, Ferland RJ, Harney M, Hill RS, Neal J, Banham AH, Brown P, Chenn A, Corbo J, Hecht J, Folkerth R, Walsh CA. Impaired proliferation and migration in human Miller-Dieker neural precursors. Ann Neurol. 2006 Jul; 60(1):137-44. PMID: 16642511.
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  92. Hecht J, Mitchell E, Baranda J, Malik I, Richards D, Navale L, D'Avirro P, Amado R. Panitumumab antitumor activity in patients (pts) with metastatic colorectal cancer (mCRC) expressing low (1-9%) or negative (<1%) levels of epidermal growth factor receptor (EGFr). J Clin Oncol. 2006 Jun 20; 24(18_suppl):3547. PMID: 27953258.
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  93. Koehne C, Bajetta E, Lin E, Van Cutsem E, Hecht J, Douillard J, Moore M, Germond C, Laurent D, Jacques C. Results of an interim analysis of a multinational randomized, double-blind, phase III study in patients (pts) with previously treated metastatic colorectal cancer (mCRC) receiving FOLFOX4 and PTK787/ZK 222584 (PTK/ZK) or placebo (CONFIRM 2). J Clin Oncol. 2006 Jun 20; 24(18_suppl):3508. PMID: 27953331.
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  94. Tworoger SS, Hecht JL, Giovannucci E, Hankinson SE. Intake of folate and related nutrients in relation to risk of epithelial ovarian cancer. Am J Epidemiol. 2006 Jun 15; 163(12):1101-11. PMID: 16554344.
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  95. Hecht JL, Pinkus JL, Pinkus GS. Monoclonal antibody MOC-31 reactivity as a marker for adenocarcinoma in cytologic preparations. Cancer. 2006 Feb 25; 108(1):56-9. PMID: 16329115.
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  96. Sheen VL, Ferland RJ, Neal J, Harney M, Hill RS, Banham A, Brown P, Chenn A, Corbo J, Hecht J, Folkerth R, Walsh CA. Neocortical neuronal arrangement in Miller Dieker syndrome. Acta Neuropathol. 2006 May; 111(5):489-96. PMID: 16456669.
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  97. Moore MJ, Goldstein D, Hamm J, Figer A, Hecht J, Gallinger S, Au H, Ding K, Christy-Bittel J, Parulekar W. Erlotinib plus gemcitabine compared to gemcitabine alone in patients with advanced pancreatic cancer. A phase III trial of the National Cancer Institute of Canada Clinical Trials Group [NCIC-CTG]. J Clin Oncol. 2005 Jun; 23(16_suppl):1. PMID: 27946620.
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  98. Drapkin R, von Horsten HH, Lin Y, Mok SC, Crum CP, Welch WR, Hecht JL. Human epididymis protein 4 (HE4) is a secreted glycoprotein that is overexpressed by serous and endometrioid ovarian carcinomas. Cancer Res. 2005 Mar 15; 65(6):2162-9. PMID: 15781627.
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  99. Huppert D, Strupp M, Rettinger N, Hecht J, Brandt T. Phobic postural vertigo--a long-term follow-up (5 to 15 years) of 106 patients. J Neurol. 2005 May; 252(5):564-9. PMID: 15742115.
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  100. Hecht JL, Ince TA, Baak JP, Baker HE, Ogden MW, Mutter GL. Prediction of endometrial carcinoma by subjective endometrial intraepithelial neoplasia diagnosis. Mod Pathol. 2005 Mar; 18(3):324-30. PMID: 15529181; PMCID: PMC2573865.
  101. Witkiewicz AK, Hecht JL, Cviko A, McKeon FD, Ince TA, Crum CP. Microglandular hyperplasia: a model for the de novo emergence and evolution of endocervical reserve cells. Hum Pathol. 2005 Feb; 36(2):154-61. PMID: 15754292.
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  102. Hecht JL. Readers' responses to the webcast video editorial entitled "resuscitating the autopsy". MedGenMed. 2005; 7(2):34; author reply 33. PMID: 16385709.
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  103. Ryley DA, Moorman DW, Hecht JL, Alper MM. A mesothelial cyst of the round ligament presenting as an inguinal hernia after gonadotropin stimulation for in vitro fertilization. Fertil Steril. 2004 Oct; 82(4):944-6. PMID: 15482776.
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  104. Drapkin R, Crum CP, Hecht JL. Expression of candidate tumor markers in ovarian carcinoma and benign ovary: evidence for a link between epithelial phenotype and neoplasia. Hum Pathol. 2004 Aug; 35(8):1014-21. PMID: 15297969.
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  105. Kabbinavar FF, Schulz J, McCleod M, Patel T, Hamm J, Hecht J, Perrou B, Griffing S, Nelson B, Novotny W. Bevacizumab (a monoclonal antibody to vascular endothelial growth factor) to prolong progression-free survival in first-line colorectal cancer (CRC) in subjects who are not suitable candidates for first-line CPT-11. J Clin Oncol. 2004 Jul 15; 22(14_suppl):3516. PMID: 28016466.
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  106. Odze RD, Farraye FA, Hecht JL, Hornick JL. Long-term follow-up after polypectomy treatment for adenoma-like dysplastic lesions in ulcerative colitis. Clin Gastroenterol Hepatol. 2004 Jul; 2(7):534-41. PMID: 15224277.
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  107. Nascimento AF, Granter SR, Cviko A, Yuan L, Hecht JL, Crum CP. Vulvar acanthosis with altered differentiation: a precursor to verrucous carcinoma? Am J Surg Pathol. 2004 May; 28(5):638-43. PMID: 15105653.
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  108. Hecht JL, Pinkus JL, Pinkus GS. Enhanced detection of atypical hyperplasia in endometrial polyps by PTEN expression. Appl Immunohistochem Mol Morphol. 2004 Mar; 12(1):36-9. PMID: 15163017.
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  109. McElrath TF, Colon I, Hecht J, Tanasijevic MJ, Norwitz ER. Neonatal respiratory distress syndrome as a function of gestational age and an assay for surfactant-to-albumin ratio. Obstet Gynecol. 2004 Mar; 103(3):463-8. PMID: 14990407.
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  110. Peng SL, Townsend MJ, Hecht JL, White IA, Glimcher LH. T-bet regulates metastasis rate in a murine model of primary prostate cancer. Cancer Res. 2004 Jan 15; 64(2):452-5. PMID: 14744755.
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  111. Qian X, Hecht JL. Pancreatic fine needle aspiration. A comparison of computed tomographic and endoscopic ultrasonographic guidance. Acta Cytol. 2003 Sep-Oct; 47(5):723-6. PMID: 14526668.
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  112. Hecht JL, Cibas ES, Kutok JL. Fine-needle aspiration cytology of lymphoproliferative disorders in the immunosuppressed patient: the diagnostic utility of in situ hybridization for Epstein-Barr virus. Diagn Cytopathol. 2002 Jun; 26(6):360-5. PMID: 12112825.
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  113. Lee BH, Hecht JL, Pinkus JL, Pinkus GS. WT1, estrogen receptor, and progesterone receptor as markers for breast or ovarian primary sites in metastatic adenocarcinoma to body fluids. Am J Clin Pathol. 2002 May; 117(5):745-50. PMID: 12090423.
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  114. Hecht JL, Lee BH, Pinkus JL, Pinkus GS. The value of Wilms tumor susceptibility gene 1 in cytologic preparations as a marker for malignant mesothelioma. Cancer. 2002 Apr 25; 96(2):105-9. PMID: 11954027.
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  115. Chen CC, Hsu L, Hecht JL, Janecka I. Bimaxillary chondrosarcoma: clinical, radiologic, and histologic correlation. AJNR Am J Neuroradiol. 2002 Apr; 23(4):667-70. PMID: 11950664.
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  116. Hecht JL, Sheets EE, Lee KR. Atypical glandular cells of undetermined significance in conventional cervical/vaginal smears and thin-layer preparations. Cancer. 2002 Feb 25; 96(1):1-4. PMID: 11836696.
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  117. Domchek SM, Hecht JL, Fleming MD, Pinkus GS, Canellos GP. Lymphomas of the breast: primary and secondary involvement. Cancer. 2002 Jan 01; 94(1):6-13. PMID: 11815954.
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  118. Hecht JL, Pinkus JL, Weinstein LJ, Pinkus GS. The value of thyroid transcription factor-1 in cytologic preparations as a marker for metastatic adenocarcinoma of lung origin. Am J Clin Pathol. 2001 Oct; 116(4):483-8. PMID: 11601132.
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  119. Thorner AR, Travis AC, Hecht JL, Conrow DS, Fisher DC. Unusual presentations of malignancy. Case 3. Mantle-cell lymphoma of soft tissue. J Clin Oncol. 2001 Jul 01; 19(13):3291-3. PMID: 11432899.
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  120. Hecht JL, McLaughlin M, Granter SR. Botfly infestation (Dermatobia hominis). Arch Pathol Lab Med. 2001 Mar; 125(3):453. PMID: 11231506.
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  121. Hecht JL, Aster JC. Molecular biology of Burkitt's lymphoma. J Clin Oncol. 2000 Nov 01; 18(21):3707-21. PMID: 11054444.
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  122. Galsky M, Darling M, Hecht J, Salgia R. Case 1: small bowel obstruction due to metastatic lung cancer. J Clin Oncol. 2000 Jan; 18(1):227-8. PMID: 10623713.
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  123. Green WB, Slovak ML, Chen IM, Pallavicini M, Hecht JL, Willman CL. Lack of IRF-1 expression in acute promyelocytic leukemia and in a subset of acute myeloid leukemias with del(5)(q31). Leukemia. 1999 Dec; 13(12):1960-71. PMID: 10602416.
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  124. Zhou G, Chen Y, Zhou L, Thirunavukkarasu K, Hecht J, Chitayat D, Gelb BD, Pirinen S, Berry SA, Greenberg CR, Karsenty G, Lee B. CBFA1 mutation analysis and functional correlation with phenotypic variability in cleidocranial dysplasia. Hum Mol Genet. 1999 Nov; 8(12):2311-6. PMID: 10545612.
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  125. Gourevitch MN, Hartel D, Tenore P, Freeman K, Marion I, Hecht J, Lowinson J. Three oral formulations of methadone. A clinical and pharmacodynamic comparison. J Subst Abuse Treat. 1999 Oct; 17(3):237-41. PMID: 10531630.
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  126. Goodman DC, Lozano P, Stukel TA, Chang Ch, Hecht J. Has asthma medication use in children become more frequent, more appropriate, or both? Pediatrics. 1999 Aug; 104(2 Pt 1):187-94. PMID: 10428993.
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  127. Emmons KM, Cargill BR, Hecht J, Goldstein M, Milman R, Abrams DB. Characteristics of patients adhering to a hospital's no-smoking policy. Prev Med. 1998 Nov-Dec; 27(6):846-53. PMID: 9922067.
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  128. Misra VK, Hecht JL, Yang AS, Honig B. Electrostatic contributions to the binding free energy of the lambdacI repressor to DNA. Biophys J. 1998 Nov; 75(5):2262-73. PMID: 9788922; PMCID: PMC1299901.
  129. Lee B, Thirunavukkarasu K, Zhou L, Pastore L, Baldini A, Hecht J, Geoffroy V, Ducy P, Karsenty G. Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia. Nat Genet. 1997 Jul; 16(3):307-10. PMID: 9207800.
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  130. Lozano P, Fishman P, VonKorff M, Hecht J. Health care utilization and cost among children with asthma who were enrolled in a health maintenance organization. Pediatrics. 1997 Jun; 99(6):757-64. PMID: 9164766.
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  131. Sharp KA, Friedman RA, Misra V, Hecht J, Honig B. Salt effects on polyelectrolyte-ligand binding: comparison of Poisson-Boltzmann, and limiting law/counterion binding models. Biopolymers. 1995 Aug; 36(2):245-62. PMID: 7492748.
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  132. Hecht JL, Kadish AS, Jiang G, Burk RD. Genetic characterization of the human papillomavirus (HPV) 18 E2 gene in clinical specimens suggests the presence of a subtype with decreased oncogenic potential. Int J Cancer. 1995 Jan 27; 60(3):369-76. PMID: 7829247.
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  133. Misra VK, Hecht JL, Sharp KA, Friedman RA, Honig B. Salt effects on protein-DNA interactions. The lambda cI repressor and EcoRI endonuclease. J Mol Biol. 1994 Apr 29; 238(2):264-80. PMID: 8158653.
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  134. Shy KK, Stergachis A, Grothaus LG, Wagner EH, Hecht J, Anderson G. Tubal sterilization and risk of subsequent hospital admission for menstrual disorders. Am J Obstet Gynecol. 1992 Jun; 166(6 Pt 1):1698-705; discussion 1705-6. PMID: 1615977.
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  135. Davis DO, Hecht J, Anderson RE. An accessory table for supine horizontal-beam polytome laminagraphy. Radiology. 1975 Nov; 117(2):478-80. PMID: 1178888.
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