Harvard Catalyst Profiles

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William Dean Carlson, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Carlson WD, Keck PC, Bosukonda D, Carlson FR. A Process for the Design and Development of Novel Bone Morphogenetic Protein-7 (BMP-7) Mimetics With an Example: THR-184. Front Pharmacol. 2022; 13:864509. PMID: 35873578; PMCID: PMC9306349.
  2. Carlson FR, Bosukonda D, Keck PC, Carlson WD. Multiorgan Damage in Patients With COVID-19: Is the TGF-ß/BMP Pathway the Missing Link? JACC Basic Transl Sci. 2020 Nov; 5(11):1145-1148. PMID: 32984657; PMCID: PMC7508496.
    Citations: 9     
  3. Bosukonda A, Carlson WD. Harnessing the BMP signaling pathway to control the formation of cancer stem cells by effects on epithelial-to-mesenchymal transition. Biochem Soc Trans. 2017 02 08; 45(1):223-228. PMID: 28202676.
    Citations: 7     Fields:    Translation:HumansCells
  4. Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis. Nat Med. 2012 Feb 05; 18(3):396-404. PMID: 22306733.
    Citations: 109     Fields:    Translation:AnimalsCells
  5. Januzzi JL, Rehman SU, Mohammed AA, Bhardwaj A, Barajas L, Barajas J, Kim HN, Baggish AL, Weiner RB, Chen-Tournoux A, Marshall JE, Moore SA, Carlson WD, Lewis GD, Shin J, Sullivan D, Parks K, Wang TJ, Gregory SA, Uthamalingam S, Semigran MJ. Use of amino-terminal pro-B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction. J Am Coll Cardiol. 2011 Oct 25; 58(18):1881-9. PMID: 22018299.
    Citations: 88     Fields:    Translation:Humans
  6. Stone PH, Lloyd-Jones DM, Kinlay S, Frei B, Carlson W, Rubenstein J, Andrews TC, Johnstone M, Sopko G, Cole H, Orav J, Selwyn AP, Creager MA. Effect of intensive lipid lowering, with or without antioxidant vitamins, compared with moderate lipid lowering on myocardial ischemia in patients with stable coronary artery disease: the Vascular Basis for the Treatment of Myocardial Ischemia Study. Circulation. 2005 Apr 12; 111(14):1747-55. PMID: 15809368.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  7. Stone PH, Lloyd-Jones DM, Johnstone M, Carlson W, Rubenstein J, Creager M, Frei B, Sopko G, Clark ME, Maccallum G, Kinlay S, Orav J, Selwyn AP. Vascular basis for the treatment of myocardial ischemia study: trial design and baseline characteristics. Am Heart J. 2004 May; 147(5):875-82. PMID: 15131545.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  8. Kinlay S, Timms T, Clark M, Karam C, Bilodeau T, Ridker PM, Rifai N, Carlson W, Lloyd-Jones DM, Johnstone M, Rubenstein J, Alexander S, Orav J, Stone PH. Comparison of effect of intensive lipid lowering with atorvastatin to less intensive lowering with lovastatin on C-reactive protein in patients with stable angina pectoris and inducible myocardial ischemia. Am J Cardiol. 2002 May 15; 89(10):1205-7. PMID: 12008177.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  9. Carlson W, Oberg K. Clinical Pharmacology of Carvedilol. J Cardiovasc Pharmacol Ther. 1999 Oct; 4(4):205-218. PMID: 10684542.
    Citations: 2     Fields:    
  10. Hirsch DR, Lee TH, Morrison RB, Carlson W, Goldhaber SZ. Shortened hospitalization by means of adjusted-dose subcutaneous heparin for deep venous thrombosis. Am Heart J. 1996 Feb; 131(2):276-80. PMID: 8579021.
    Citations: 3     Fields:    Translation:Humans
  11. Griffith DL, Keck PC, Sampath TK, Rueger DC, Carlson WD. Three-dimensional structure of recombinant human osteogenic protein 1: structural paradigm for the transforming growth factor beta superfamily. Proc Natl Acad Sci U S A. 1996 Jan 23; 93(2):878-83. PMID: 8570652; PMCID: PMC40151.
    Citations: 43     Fields:    Translation:HumansCells
  12. Hanrahan JP, Choo PW, Carlson W, Greineder D, Faich GA, Platt R. Terfenadine-associated ventricular arrhythmias and QTc interval prolongation. A retrospective cohort comparison with other antihistamines among members of a health maintenance organization. Ann Epidemiol. 1995 May; 5(3):201-9. PMID: 7606309.
    Citations: 20     Fields:    Translation:Humans
  13. Griffith DL, Oppermann H, Rueger DC, Sampath TK, Tucker RF, Carlson WD. Crystallization and preliminary crystallographic data of recombinant human osteogenic protein-1 (hOP-1). J Mol Biol. 1994 Dec 16; 244(5):657-8. PMID: 7990148.
    Citations: 1     Fields:    Translation:HumansCells
  14. Zusman RM, Hui KY, Nussberger J, Christensen DM, Higgins J, Carlson WD, Schoenfeld D, Haber E. R-PEP-27, a potent renin inhibitor, decreases plasma angiotensin II and blood pressure in normal volunteers. Am J Hypertens. 1994 Apr; 7(4 Pt 1):295-301. PMID: 8031544.
    Citations: 2     Fields:    Translation:Humans
  15. Galen FX, Evin G, Carelli C, Bouhnik J, Michel JB, Ferhentz JA, Le N'Guyen D, Seyer R, Carlson WD, Haber E, et al. [Production and characterization of human antirenin antibodies prepared with synthetic immunogens]. Arch Mal Coeur Vaiss. 1988 Jun; 81 Spec No:199-201. PMID: 2461182.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  16. Evin G, Galen FX, Carlson WD, Handschumacher M, Novotný J, Bouhnik J, Ménard J, Corvol P, Haber E. Characterization of five epitopes of human renin from a computer model. Biochemistry. 1988 Jan 12; 27(1):156-64. PMID: 2450565.
    Citations: 1     Fields:    Translation:HumansCells
  17. Novotny J, Bruccoleri RE, Carlson WD, Handschumacher M, Haber E. Antigenicity of myohemerythrin. Science. 1987 Dec 11; 238(4833):1584-6. PMID: 2446393.
    Citations: 6     Fields:    Translation:Animals
  18. Galen FX, Evin G, Carelli C, Bouhnik J, Michel JB, Ferhentz JA, Le N'Guyen D, Seyer R, Carlson WD, Haber E, et al. Production and characterization of human renin antibodies prepared with synthetic immunogens. J Hypertens Suppl. 1987 Dec; 5(5):S11-4. PMID: 2450977.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  19. Suguna K, Padlan EA, Smith CW, Carlson WD, Davies DR. Binding of a reduced peptide inhibitor to the aspartic proteinase from Rhizopus chinensis: implications for a mechanism of action. Proc Natl Acad Sci U S A. 1987 Oct; 84(20):7009-13. PMID: 3313384; PMCID: PMC299218.
    Citations: 42     Fields:    Translation:AnimalsCells
  20. Hui KY, Carlson WD, Bernatowicz MS, Haber E. Analysis of structure-activity relationships in renin substrate analogue inhibitory peptides. J Med Chem. 1987 Aug; 30(8):1287-95. PMID: 3302256.
    Citations: 2     Fields:    Translation:HumansAnimals
  21. Summers NL, Carlson WD, Karplus M. Analysis of side-chain orientations in homologous proteins. J Mol Biol. 1987 Jul 05; 196(1):175-98. PMID: 3309349.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  22. Carlson WD, Handschumacher M, Summers N, Karplus M, Haber E. Models for the three-dimensional structure of renin inhibitors bound in the active site of human renin: an analysis of the properties that produce tight binding. J Cardiovasc Pharmacol. 1987; 10 Suppl 7:S91-3. PMID: 2485071.
    Citations:    Fields:    Translation:HumansCells
  23. Galen FX, Evin G, Carelli C, Bouhnik J, Michel JB, Ferhentz JA, Le N'guyen D, Seyer R, Carlson WD, Castro B, et al. Chemical approach of synthetic immunogens from human renin. Int J Rad Appl Instrum B. 1987; 14(4):305-12. PMID: 2443468.
    Citations:    Fields:    Translation:HumansCells
  24. Haber E, Hui KY, Carlson WD, Bernatowicz MS. Renin inhibitors: a search for principles of design. J Cardiovasc Pharmacol. 1987; 10 Suppl 7:S54-8. PMID: 2485064.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  25. Day RP, Hui KY, Gure M, Carlson WD, Dzau VJ, Haber E. A monoclonal antibody specific for the amino terminal sequence of human prorenin identifies a common epitope on renal and amniotic fluid inactive renins. J Hypertens. 1986 Jun; 4(3):375-81. PMID: 2426349.
    Citations: 1     Fields:    Translation:HumansAnimals
  26. Evin G, Carlson WD, Handschumacher M, Novotný J, Matsueda GR, Haber E, Bouhnik J, Galen FX, Ménard J, Corvol P. Study of the antigenic determinants of human renin. Hypertension. 1986 Jun; 8(6 Pt 2):II72-7. PMID: 2424834.
    Citations: 1     Fields:    Translation:HumansCells
  27. Richards FM, Wyckoff HW, Carlson WD, Allewell NM, Lee B, Mitsui Y. Protein structure, ribonuclease-S and nucleotide interactions. Cold Spring Harb Symp Quant Biol. 1972; 36:35-43. PMID: 4508150.
    Citations: 13     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.