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Andrew James MacGinnitie, M.D.,Ph.D.

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  1. Maurer M, Magerl M, Betschel S, Aberer W, Ansotegui IJ, Aygören-Pürsün E, Banerji A, Bara NA, Boccon-Gibod I, Bork K, Bouillet L, Boysen HB, Brodszki N, Busse PJ, Bygum A, Caballero T, Cancian M, Castaldo AJ, Cohn DM, Csuka D, Farkas H, Gompels M, Gower R, Grumach AS, Guidos-Fogelbach G, Hide M, Kang HR, Kaplan AP, Katelaris CH, Kiani-Alikhan S, Lei WT, Lockey RF, Longhurst H, Lumry W, MacGinnitie A, Malbran A, Martinez Saguer I, Matta Campos JJ, Nast A, Nguyen D, Nieto-Martinez SA, Pawankar R, Peter J, Porebski G, Prior N, Reshef A, Riedl M, Ritchie B, Sheikh FR, Smith WB, Spaeth PJ, Stobiecki M, Toubi E, Varga LA, Weller K, Zanichelli A, Zhi Y, Zuraw B, Craig T. The international WAO/EAACI guideline for the management of hereditary angioedema - The 2021 revision and update. World Allergy Organ J. 2022 Mar; 15(3):100627. PMID: 35497649; PMCID: PMC9023902.
    Citations: 1     
  2. Maurer M, Magerl M, Betschel S, Aberer W, Ansotegui IJ, Aygören-Pürsün E, Banerji A, Bara NA, Boccon-Gibod I, Bork K, Bouillet L, Boysen HB, Brodszki N, Busse PJ, Bygum A, Caballero T, Cancian M, Castaldo A, Cohn DM, Csuka D, Farkas H, Gompels M, Gower R, Grumach AS, Guidos-Fogelbach G, Hide M, Kang HR, Kaplan AP, Katelaris C, Kiani-Alikhan S, Lei WT, Lockey R, Longhurst H, Lumry WR, MacGinnitie A, Malbran A, Martinez Saguer I, Matta JJ, Nast A, Nguyen D, Nieto-Martinez SA, Pawankar R, Peter J, Porebski G, Prior N, Reshef A, Riedl M, Ritchie B, Rafique Sheikh F, Smith WB, Spaeth PJ, Stobiecki M, Toubi E, Varga LA, Weller K, Zanichelli A, Zhi Y, Zuraw B, Craig T. The international WAO/EAACI guideline for the management of hereditary angioedema-The 2021 revision and update. Allergy. 2022 07; 77(7):1961-1990. PMID: 35006617.
    Citations: 3     Fields:    Translation:Humans
  3. Pongracic JA, Gagnon R, Sussman G, Siri D, Oriel RC, Brown-Whitehorn TF, Green TD, Campbell DE, Anvari S, Berger WE, Bird JA, Chan ES, Cheema A, Chinthrajah RS, Chong HJ, Dowling PJ, Fineman SM, Fleischer DM, Gonzalez-Reyes E, Kim EH, Lanser BJ, MacGinnitie A, Mehta H, Petroni D, Rupp N, Schneider LC, Scurlock AM, Sher LD, Shreffler WG, Sindher SB, Stillerman A, Wood R, Yang WH, Bois T, Sampson HA, Bégin P. Safety of Epicutaneous Immunotherapy in Peanut-Allergic Children: REALISE Randomized Clinical Trial Results. J Allergy Clin Immunol Pract. 2022 07; 10(7):1864-1873.e10. PMID: 34848381.
    Citations: 1     Fields:    Translation:HumansAnimalsCTClinical Trials
  4. Chen G, Shrock EL, Li MZ, Spergel JM, Nadeau KC, Pongracic JA, Umetsu DT, Rachid R, MacGinnitie AJ, Phipatanakul W, Schneider L, Oettgen HC, Elledge SJ. High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy. Cell Rep Med. 2021 10 19; 2(10):100410. PMID: 34755130; PMCID: PMC8563412.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  5. Hatoun J, Correa ET, MacGinnitie AJ, Gaffin JM, Vernacchio L. Development and Validation of the Asthma Exacerbation Risk Score Using Claims Data. Acad Pediatr. 2022 Jan-Feb; 22(1):47-54. PMID: 34256177.
    Citations: 1     Fields:    Translation:Humans
  6. Esty B, Maciag MC, Bartnikas LM, Petty CR, MacGinnitie AJ, Sheehan WJ, Phipatanakul W. Predicting outcomes of baked egg and baked milk oral food challenges by using a ratio of food-specific IgE to total IgE. J Allergy Clin Immunol Pract. 2021 04; 9(4):1750-1752.e1. PMID: 33217611; PMCID: PMC8043965.
    Citations:    Fields:    Translation:HumansAnimals
  7. Broyles AD, Banerji A, Barmettler S, Biggs CM, Blumenthal K, Brennan PJ, Breslow RG, Brockow K, Buchheit KM, Cahill KN, Cernadas J, Chiriac AM, Crestani E, Demoly P, Dewachter P, Dilley M, Farmer JR, Foer D, Fried AJ, Garon SL, Giannetti MP, Hepner DL, Hong DI, Hsu JT, Kothari PH, Kyin T, Lax T, Lee MJ, Lee-Sarwar K, Liu A, Logsdon S, Louisias M, MacGinnitie A, Maciag M, Minnicozzi S, Norton AE, Otani IM, Park M, Patil S, Phillips EJ, Picard M, Platt CD, Rachid R, Rodriguez T, Romano A, Stone CA, Torres MJ, Verdú M, Wang AL, Wickner P, Wolfson AR, Wong JT, Yee C, Zhou J, Castells M. Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs. J Allergy Clin Immunol Pract. 2020 10; 8(9S):S16-S116. PMID: 33039007.
    Citations: 28     Fields:    Translation:Humans
  8. Maurer M, Aberer W, Agondi R, Al-Ahmad M, Al-Nesf MA, Ansotegui I, Arnaout R, Arruda LK, Asero R, Aygören-Pürsün E, Banerji A, Bauer A, Ben-Shoshan M, Berardi A, Bernstein JA, Betschel S, Bindslev-Jensen C, Bizjak M, Boccon-Gibod I, Bork K, Bouillet L, Boysen HB, Brodszki N, Broesby-Olsen S, Busse P, Buttgereit T, Bygum A, Caballero T, Campos RA, Cancian M, Cherrez-Ojeda I, Cohn DM, Costa C, Craig T, Criado PR, Criado RF, Csuka D, Dissemond J, Du-Thanh A, Ensina LF, Ertas R, Fabiani JE, Fantini C, Farkas H, Ferrucci SM, Figueras-Nart I, Fili NL, Fomina D, Fukunaga A, Gelincik A, Giménez-Arnau A, Godse K, Gompels M, Gonçalo M, Gotua M, Gower R, Grumach AS, Guidos-Fogelbach G, Hide M, Ilina N, Inomata N, Jakob T, Josviack DO, Kang HR, Kaplan A, Kasperska-Zajac A, Katelaris C, Kessel A, Kleinheinz A, Kocatürk E, Košnik M, Krasowska D, Kulthanan K, Kumaran MS, Larco Sousa JI, Longhurst HJ, Lumry W, MacGinnitie A, Magerl M, Makris MP, Malbrán A, Marsland A, Martinez-Saguer I, Medina IV, Meshkova R, Metz M, Nasr I, Nicolay J, Nishigori C, Ohsawa I, Özyurt K, Papadopoulos NG, Parisi CAS, Peter JG, Pfützner W, Popov T, Prior N, Ramon GD, Reich A, Reshef A, Riedl MA, Ritchie B, Röckmann-Helmbach H, Rudenko M, Salman A, Sanchez-Borges M, Schmid-Grendelmeier P, Serpa FS, Serra-Baldrich E, Sheikh FR, Smith W, Soria A, Staubach P, Steiner UC, Stobiecki M, Sussman G, Tagka A, Thomsen SF, Treudler R, Valle S, van Doorn M, Varga L, Vázquez DO, Wagner N, Wang L, Weber-Chrysochoou C, Ye YM, Zalewska-Janowska A, Zanichelli A, Zhao Z, Zhi Y, Zuberbier T, Zwiener RD, Castaldo A. Definition, aims, and implementation of GA2 LEN/HAEi Angioedema Centers of Reference and Excellence. Allergy. 2020 08; 75(8):2115-2123. PMID: 32248571.
    Citations: 7     Fields:    Translation:Humans
  9. Ahmed F, Fried AJ, Spielman S, Secor W, MacGinnitie AJ. Utility of measuring tryptase levels in children and young adults. Ann Allergy Asthma Immunol. 2019 10; 123(4):398-399. PMID: 31400462.
    Citations: 1     Fields:    Translation:HumansCells
  10. Lunstead J, Weitzman ER, Harstad E, Dedeoglu F, Gaffin JM, Garvey KC, MacGinnitie A, Rufo PA, Fishman LN, Wisk LE, Levy S. Screening and Counseling for Alcohol Use in Adolescents With Chronic Medical Conditions in the Ambulatory Setting. J Adolesc Health. 2019 06; 64(6):804-806. PMID: 31122509.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  11. Stranks AJ, Minnicozzi SC, Miller SJ, Burton OT, Logsdon SL, Spergel JM, Nadeau KC, Pongracic JA, Umetsu DT, Rachid R, MacGinnitie AJ, Schneider LC, Oettgen HC. Immunoglobulin E blockade during food allergen ingestion enhances the induction of inhibitory immunoglobulin G antibodies. Ann Allergy Asthma Immunol. 2019 02; 122(2):213-215. PMID: 30404033; PMCID: PMC6360101.
    Citations: 6     Fields:    Translation:Humans
  12. MacGinnitie A, Kamalia R, Alvernaz L, Timmons K, Hamel V, Lafreniere A, Minsk B, Platt C, Lee P, Burke-Roberts E, Dilley M. A quality improvement initiative to increase access to food challenges. Pediatr Allergy Immunol. 2018 06; 29(4):447-449. PMID: 29512886.
    Citations:    Fields:    Translation:Humans
  13. MacGinnitie AJ, Young MC. The Role of Food Challenges in Clinical Practice. J Allergy Clin Immunol Pract. 2018 Mar - Apr; 6(2):353-360. PMID: 29524990.
    Citations: 2     Fields:    Translation:Humans
  14. Bird JA, Spergel JM, Jones SM, Rachid R, Assa'ad AH, Wang J, Leonard SA, Laubach SS, Kim EH, Vickery BP, Davis BP, Heimall J, Cianferoni A, MacGinnitie AJ, Crestani E, Burks AW. Efficacy and Safety of AR101 in Oral Immunotherapy for Peanut Allergy: Results of ARC001, a Randomized, Double-Blind, Placebo-Controlled Phase 2 Clinical Trial. J Allergy Clin Immunol Pract. 2018 Mar - Apr; 6(2):476-485.e3. PMID: 29092786.
    Citations: 40     Fields:    Translation:HumansAnimalsCTClinical Trials
  15. Akuete K, Guffey D, Israelsen RB, Broyles JM, Higgins LJ, Green TD, Naimi DR, MacGinnitie AJ, Vitalpur G, Minard CG, Davis CM. Multicenter prevalence of anaphylaxis in clinic-based oral food challenges. Ann Allergy Asthma Immunol. 2017 10; 119(4):339-348.e1. PMID: 28890356.
    Citations: 8     Fields:    Translation:HumansAnimals
  16. MacGinnite A. Update on Potential Therapies for IgE-Mediated Food Allergy. Curr Allergy Asthma Rep. 2017 Jan; 17(1):4. PMID: 28181151.
    Citations: 3     Fields:    Translation:HumansAnimals
  17. MacGinnitie AJ, Rachid R, Gragg H, Little SV, Lakin P, Cianferoni A, Heimall J, Makhija M, Robison R, Chinthrajah RS, Lee J, Lebovidge J, Dominguez T, Rooney C, Lewis MO, Koss J, Burke-Roberts E, Chin K, Logvinenko T, Pongracic JA, Umetsu DT, Spergel J, Nadeau KC, Schneider LC. Omalizumab facilitates rapid oral desensitization for peanut allergy. J Allergy Clin Immunol. 2017 Mar; 139(3):873-881.e8. PMID: 27609658; PMCID: PMC5369605.
    Citations: 71     Fields:    Translation:HumansAnimalsCTClinical Trials
  18. Simberloff T, Parambi R, Bartnikas LM, Broyles AD, Hamel V, Timmons KG, Miller DM, Graham DA, Schneider LC, MacGinnitie AJ. Implementation of a Standardized Clinical Assessment and Management Plan (SCAMP) for Food Challenges. J Allergy Clin Immunol Pract. 2017 Mar - Apr; 5(2):335-344.e3. PMID: 27373725.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  19. Levy S, Dedeoglu F, Gaffin JM, Garvey KC, Harstad E, MacGinnitie A, Rufo PA, Huang Q, Ziemnik RE, Wisk LE, Weitzman ER. A Screening Tool for Assessing Alcohol Use Risk among Medically Vulnerable Youth. PLoS One. 2016; 11(5):e0156240. PMID: 27227975.
    Citations: 11     Fields:    Translation:HumansPHPublic Health
  20. Craig TJ, Schneider LC, MacGinnitie AJ. Plasma-derived C1-INH for managing hereditary angioedema in pediatric patients: A systematic review. Pediatr Allergy Immunol. 2015 Sep; 26(6):537-44. PMID: 26111105.
    Citations: 6     Fields:    Translation:Humans
  21. Craig TJ, Li HH, Riedl M, Bernstein JA, Lumry WR, MacGinnitie AJ, Stolz LE, Biedenkapp J, Chyung Y. Characterization of anaphylaxis after ecallantide treatment of hereditary angioedema attacks. J Allergy Clin Immunol Pract. 2015 Mar-Apr; 3(2):206-212.e4. PMID: 25609335.
    Citations: 11     Fields:    Translation:Humans
  22. MacGinnitie AJ. Pediatric hereditary angioedema. Pediatr Allergy Immunol. 2014 Aug; 25(5):420-7. PMID: 24313851.
    Citations: 5     Fields:    Translation:Humans
  23. MacGinnitie AJ, Davis-Lorton M, Stolz LE, Tachdjian R. Use of ecallantide in pediatric hereditary angioedema. Pediatrics. 2013 Aug; 132(2):e490-7. PMID: 23878046.
    Citations: 10     Fields:    Translation:Humans
  24. Lumry WR, Bernstein JA, Li HH, MacGinnitie AJ, Riedl M, Soteres DF, Craig TJ, Campion M, Iarrobino R, Stolz LE, Pullman WE. Efficacy and safety of ecallantide in treatment of recurrent attacks of hereditary angioedema: open-label continuation study. Allergy Asthma Proc. 2013 Mar-Apr; 34(2):155-61. PMID: 23484891.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  25. Li HH, Campion M, Craig TJ, Soteres DF, Riedl M, Lumry WR, MacGinnitie AJ, Shea EP, Bernstein JA. Analysis of hereditary angioedema attacks requiring a second dose of ecallantide. Ann Allergy Asthma Immunol. 2013 Mar; 110(3):168-72. PMID: 23548526.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  26. Sheffer AL, MacGinnitie AJ, Campion M, Stolz LE, Pullman WE. Outcomes after ecallantide treatment of laryngeal hereditary angioedema attacks. Ann Allergy Asthma Immunol. 2013 Mar; 110(3):184-188.e2. PMID: 23548529.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  27. Jacobs TS, Jones BL, MacGinnitie AJ. Long-acting beta-agonists and the risk of intensive care unit admission in children. J Asthma. 2012 Jun; 49(5):450-5. PMID: 22540879.
    Citations: 1     Fields:    Translation:Humans
  28. MacGinnitie AJ, Campion M, Stolz LE, Pullman WE. Ecallantide for treatment of acute hereditary angioedema attacks: analysis of efficacy by patient characteristics. Allergy Asthma Proc. 2012 Mar-Apr; 33(2):178-85. PMID: 22525395.
    Citations: 2     Fields:    Translation:Humans
  29. Ruffner MA, Finegold DN, MacGinnitie AJ. Infant with unusual food reactions. Acta Paediatr. 2011 Oct; 100(10):1289, 1394-5. PMID: 21916981.
    Citations:    Fields:    Translation:HumansAnimals
  30. McHugh BM, MacGinnitie AJ. Indoor allergen sensitization and the risk of asthma and eczema in children in Pittsburgh. Allergy Asthma Proc. 2011 Sep-Oct; 32(5):372-6. PMID: 22195690.
    Citations: 9     Fields:    Translation:HumansAnimals
  31. Burke S, Petrov A, Johnson J, MacGinnitie A. Successful use of ecallantide to treat a hereditary angioedema attack after failure of C1 inhibitor prophylaxis. Ann Allergy Asthma Immunol. 2011 Aug; 107(2):181-2. PMID: 21802029.
    Citations: 1     Fields:    Translation:Humans
  32. MacGinnitie A, Aloi F, Mishra S. Clinical characteristics of pediatric patients evaluated for primary immunodeficiency. Pediatr Allergy Immunol. 2011 Nov; 22(7):671-5. PMID: 21449988.
    Citations: 8     Fields:    Translation:Humans
  33. Owens G, MacGinnitie A. Higher-ovalbumin-content influenza vaccines are well tolerated in children with egg allergy. J Allergy Clin Immunol. 2011 Jan; 127(1):264-5. PMID: 21094520.
    Citations: 7     Fields:    Translation:HumansCells
  34. MacGinnitie A. In utero anaphylaxis. Med Hypotheses. 2011 Jan; 76(1):70-2. PMID: 20850225.
    Citations: 1     Fields:    Translation:Humans
  35. He R, Kim HY, Yoon J, Oyoshi MK, MacGinnitie A, Goya S, Freyschmidt EJ, Bryce P, McKenzie AN, Umetsu DT, Oettgen HC, Geha RS. Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13. J Allergy Clin Immunol. 2009 Oct; 124(4):761-70.e1. PMID: 19815118; PMCID: PMC2895457.
    Citations: 45     Fields:    Translation:AnimalsCells
  36. Puglisi G, Netravali MA, MacGinnitie AJ, Bonagura VR. 11q terminal deletion disorder and common variable immunodeficiency. Ann Allergy Asthma Immunol. 2009 Sep; 103(3):267-8. PMID: 19788026.
    Citations: 4     Fields:    Translation:Humans
  37. Scholnicoff ET, MacGinnitie AJ, Lin PL, Darville T. Chronic granulomatous disease in an adolescent with recurrent impetigo and cholecystectomy. Pediatr Infect Dis J. 2009 Mar; 28(3):255-7. PMID: 19165129.
    Citations:    Fields:    Translation:HumansCells
  38. Kapadia SB, Macginnitie AJ, Shaw PH. X-linked lymphoproliferative disease in an EBV-negative patient presenting with pancytopenia. Pediatr Blood Cancer. 2008 Jun; 50(6):1296-7. PMID: 18293382.
    Citations:    Fields:    Translation:HumansCells
  39. MacGinnitie AJ, Walensky LD, Turvey SE, Orange JS, Bonilla FA, Silverman LB, Oettgen H. Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge. Pediatr Allergy Immunol. 2003 Oct; 14(5):409-11. PMID: 14641613.
    Citations: 3     Fields:    Translation:Humans
  40. MacGinnitie AJ, Geha R. X-linked lymphoproliferative disease: genetic lesions and clinical consequences. Curr Allergy Asthma Rep. 2002 Sep; 2(5):361-7. PMID: 12165201.
    Citations: 2     Fields:    Translation:HumansCells
  41. Madsen P, Anant S, Rasmussen HH, Gromov P, Vorum H, Dumanski JP, Tommerup N, Collins JE, Wright CL, Dunham I, MacGinnitie AJ, Davidson NO, Celis JE. Psoriasis upregulated phorbolin-1 shares structural but not functional similarity to the mRNA-editing protein apobec-1. J Invest Dermatol. 1999 Aug; 113(2):162-9. PMID: 10469298.
    Citations: 22     Fields:    Translation:Cells
  42. Anant S, Martin SA, Yu H, MacGinnitie AJ, Devaney E, Davidson NO. A cytidine deaminase expressed in the post-infective L3 stage of the filarial nematode, Brugia pahangi, has a novel RNA-binding activity. Mol Biochem Parasitol. 1997 Sep; 88(1-2):105-14. PMID: 9274872.
    Citations: 2     Fields:    Translation:AnimalsCells
  43. Anant S, MacGinnitie AJ, Davidson NO. apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, is a novel RNA-binding protein. J Biol Chem. 1995 Jun 16; 270(24):14762-7. PMID: 7782342.
    Citations: 35     Fields:    Translation:AnimalsCells
  44. MacGinnitie AJ, Anant S, Davidson NO. Mutagenesis of apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, reveals distinct domains that mediate cytosine nucleoside deaminase, RNA binding, and RNA editing activity. J Biol Chem. 1995 Jun 16; 270(24):14768-75. PMID: 7782343.
    Citations: 31     Fields:    Translation:AnimalsCells
  45. Davidson NO, Anant S, MacGinnitie AJ. Apolipoprotein B messenger RNA editing: insights into the molecular regulation of post-transcriptional cytidine deamination. Curr Opin Lipidol. 1995 Apr; 6(2):70-4. PMID: 7773570.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  46. Anant S, MacGinnitie AJ, Davidson NO. The binding of apobec-1 to mammalian apo B RNA is stabilized by the presence of complementation factors which are required for post-transcriptional editing. Nucleic Acids Symp Ser. 1995; (33):99-102. PMID: 8643413.
    Citations: 2     Fields:    Translation:AnimalsCells
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