Harvard Catalyst Profiles

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I-Cheng Ho, Ph.D., M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R03AI155935 (HO, I-CHENG) Nov 17, 2020 - Oct 31, 2022
    Detecting RORgt Citrullination
    Role: Principal Investigator
  2. R21AR074788 (HO, I-CHENG) Sep 7, 2018 - Aug 31, 2021
    Utilizing the RA signature to predict TNFi response
    Role: Principal Investigator
  3. R01AR070171 (HO, I-CHENG) Sep 12, 2017 - Jul 31, 2022
    Causes and Roles of Hypercitrullination in Preclinical Rheumatoid Arthritis
    Role: Principal Investigator
  4. R03AI097724 (HO, I-CHENG) Feb 15, 2012 - Jan 31, 2014
    Phenotypic characterization of itm2a-deficiency in T cells
    Role: Principal Investigator
  5. R03AI081052 (HO, I-CHENG) Jul 20, 2009 - Jun 30, 2012
    Regulation of IL-2 expression by the transcription factor Ets-1
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ho CH, Silva AA, Giles JT, Bathon JM, Solomon DH, Liao KP, Ho IC. Validation of a Bioassay for Predicting Response to Tumor Necrosis Factor Inhibitors in Rheumatoid Arthritis. Arthritis Rheumatol. 2021 Jun; 73(6):1086-1087. PMID: 33426780.
    Citations:    Fields:    
  2. Sun B, Chang HH, Salinger A, Tomita B, Bawadekar M, Holmes CL, Shelef MA, Weerapana E, Thompson PR, Ho IC. Reciprocal regulation of Th2 and Th17 cells by PAD2-mediated citrullination. JCI Insight. 2019 11 14; 4(22). PMID: 31723060.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  3. Yang JS, Hsu JW, Park SY, Lee SY, Li J, Bai M, Alves C, Tseng W, Michelet X, Ho IC, Hsu VW. ALDH7A1 inhibits the intracellular transport pathways during hypoxia and starvation to promote cellular energy homeostasis. Nat Commun. 2019 09 06; 10(1):4068. PMID: 31492851.
    Citations: 1     Fields:    Translation:HumansCells
  4. Chang HH, Ho CH, Tomita B, Silva AA, Sparks JA, Karlson EW, Rao DA, Lee YC, Ho IC. Utilizing a PTPN22 gene signature to predict response to targeted therapies in rheumatoid arthritis. J Autoimmun. 2019 07; 101:121-130. PMID: 31030958.
    Citations: 2     Fields:    Translation:HumansCells
  5. Newman JP, Wang GY, Arima K, Guan SP, Waters MR, Cavenee WK, Pan E, Aliwarga E, Chong ST, Kok CYL, Endaya BB, Habib AA, Horibe T, Ng WH, Ho IAW, Hui KM, Kordula T, Lam PYP. Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme. Nat Commun. 2017 12 04; 8(1):1913. PMID: 29203859.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  6. Sun B, Dwivedi N, Bechtel TJ, Paulsen JL, Muth A, Bawadekar M, Li G, Thompson PR, Shelef MA, Schiffer CA, Weerapana E, Ho IC. Citrullination of NF-?B p65 promotes its nuclear localization and TLR-induced expression of IL-1ß and TNFa. Sci Immunol. 2017 Jun 09; 2(12). PMID: 28783661.
    Citations: 21     Fields:    
  7. Chang HH, Liu GY, Dwivedi N, Sun B, Okamoto Y, Kinslow JD, Deane KD, Demoruelle MK, Norris JM, Thompson PR, Sparks JA, Rao DA, Karlson EW, Hung HC, Holers VM, Ho IC. A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22. JCI Insight. 2016 Oct 20; 1(17):e90045. PMID: 27777982.
    Citations: 11     Fields:    Translation:HumansCells
  8. Ho IC, Miaw SC. Regulation of IL-4 Expression in Immunity and Diseases. Adv Exp Med Biol. 2016; 941:31-77. PMID: 27734408.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  9. Chang HH, Dwivedi N, Nicholas AP, Ho IC. The W620 Polymorphism in PTPN22 Disrupts Its Interaction With Peptidylarginine Deiminase Type 4 and Enhances Citrullination and NETosis. Arthritis Rheumatol. 2015 Sep; 67(9):2323-34. PMID: 26019128.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  10. Liang MH, Couto MC, Duarte CC, Gall V, White P, Naides S, Schumacher HR, Hwang AS, Holers VM, Deane KD, Gupta S, Ho IC, Finckh A, Kopec J, Choi CB, Sayre EC. An Internet-based technique for the identification of persons with symptoms of inflammatory polyarthritis of less than 12 weeks. Clin Rheumatol. 2015 Mar; 34(3):465-70. PMID: 25339123.
    Citations: 2     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  11. Tai TS, Pai SY, Ho IC. Itm2a, a target gene of GATA-3, plays a minimal role in regulating the development and function of T cells. PLoS One. 2014; 9(5):e96535. PMID: 24831988.
    Citations: 7     Fields:    Translation:AnimalsCells
  12. Wang SC, Tsou HH, Chung RH, Chang YS, Fang CP, Chen CH, Ho IK, Kuo HW, Liu SC, Shih YH, Wu HY, Huang BH, Lin KM, Chen AC, Hsiao CF, Liu YL. The association of genetic polymorphisms in the ?-opioid receptor 1 gene with body weight, alcohol use, and withdrawal symptoms in patients with methadone maintenance. J Clin Psychopharmacol. 2014 Apr; 34(2):205-11. PMID: 24525640.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  13. Chang HH, Miaw SC, Tseng W, Sun YW, Liu CC, Tsao HW, Ho IC. PTPN22 modulates macrophage polarization and susceptibility to dextran sulfate sodium-induced colitis. J Immunol. 2013 Sep 01; 191(5):2134-43. PMID: 23913970.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  14. Wu SL, Wang SC, Tsou HH, Kuo HW, Ho IK, Liu SW, Hsu YT, Chang YS, Liu YL. Hepatitis C virus infection influences the S-methadone metabolite plasma concentration. PLoS One. 2013; 8(7):e69310. PMID: 23935979.
    Citations: 3     Fields:    Translation:HumansCells
  15. Chen YT, Tsou HH, Kuo HW, Fang CP, Wang SC, Ho IK, Chang YS, Chen CH, Hsiao CF, Wu HY, Lin KM, Chen ACh, Tsai-Wu JJ, Liu YL. OPRM1 genetic polymorphisms are associated with the plasma nicotine metabolite cotinine concentration in methadone maintenance patients: a cross sectional study. J Hum Genet. 2013 Feb; 58(2):84-90. PMID: 23223006.
    Citations: 8     Fields:    Translation:Humans
  16. Tai TS, Pai SY, Ho IC. GATA-3 regulates the homeostasis and activation of CD8+ T cells. J Immunol. 2013 Jan 01; 190(1):428-37. PMID: 23225883.
    Citations: 17     Fields:    Translation:AnimalsCells
  17. Wang KC, Lee YJ, Fan LW, Yang PP, Tao PL, Ho IK, Tien LT. Mu-opioid receptor knockout mice are more sensitive to chlordiazepoxide-induced anxiolytic behavior. Brain Res Bull. 2013 Jan; 90:137-41. PMID: 23142328.
    Citations: 1     Fields:    Translation:Animals
  18. Chien CC, Lee YJ, Fan LW, Ho IK, Tien LT. Naloxonazine, a specific mu-opioid receptor antagonist, attenuates the increment of locomotor activity induced by acute methamphetamine in mice. Toxicol Lett. 2012 Jul 07; 212(1):61-5. PMID: 22564758.
    Citations: 3     Fields:    Translation:AnimalsCells
  19. Chang HH, Tai TS, Lu B, Iannaccone C, Cernadas M, Weinblatt M, Shadick N, Miaw SC, Ho IC. PTPN22.6, a dominant negative isoform of PTPN22 and potential biomarker of rheumatoid arthritis. PLoS One. 2012; 7(3):e33067. PMID: 22427951.
    Citations: 13     Fields:    Translation:HumansCells
  20. Grenningloh R, Tai TS, Frahm N, Hongo TC, Chicoine AT, Brander C, Kaufmann DE, Ho IC. Ets-1 maintains IL-7 receptor expression in peripheral T cells. J Immunol. 2011 Jan 15; 186(2):969-76. PMID: 21148801.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  21. Chiang YC, Hung TW, Lee CW, Yan JY, Ho IK. Enhancement of tolerance development to morphine in rats prenatally exposed to morphine, methadone, and buprenorphine. J Biomed Sci. 2010 Jun 07; 17:46. PMID: 20529288.
    Citations: 8     Fields:    Translation:HumansAnimals
  22. Pot C, Jin H, Awasthi A, Liu SM, Lai CY, Madan R, Sharpe AH, Karp CL, Miaw SC, Ho IC, Kuchroo VK. Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. J Immunol. 2009 Jul 15; 183(2):797-801. PMID: 19570826.
    Citations: 207     Fields:    Translation:AnimalsCells
  23. Ho IC. m(en)TOR(ing) differentiating T helper cells. Immunity. 2009 Jun 19; 30(6):759-61. PMID: 19538925.
    Citations: 2     Fields:    Translation:AnimalsCells
  24. Ho IC, Tai TS, Pai SY. GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 2009 Feb; 9(2):125-35. PMID: 19151747.
    Citations: 132     Fields:    Translation:HumansAnimalsCells
  25. Bauquet AT, Jin H, Paterson AM, Mitsdoerffer M, Ho IC, Sharpe AH, Kuchroo VK. The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells. Nat Immunol. 2009 Feb; 10(2):167-75. PMID: 19098919.
    Citations: 319     Fields:    Translation:AnimalsCells
  26. Dardalhon V, Awasthi A, Kwon H, Galileos G, Gao W, Sobel RA, Mitsdoerffer M, Strom TB, Elyaman W, Ho IC, Khoury S, Oukka M, Kuchroo VK. IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nat Immunol. 2008 Dec; 9(12):1347-55. PMID: 18997793.
    Citations: 438     Fields:    Translation:AnimalsCells
  27. Grenningloh R, Miaw SC, Moisan J, Graves BJ, Ho IC. Role of Ets-1 phosphorylation in the effector function of Th cells. Eur J Immunol. 2008 Jun; 38(6):1700-5. PMID: 18465773.
    Citations: 9     Fields:    Translation:AnimalsCells
  28. Kouros-Mehr H, Bechis SK, Slorach EM, Littlepage LE, Egeblad M, Ewald AJ, Pai SY, Ho IC, Werb Z. GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model. Cancer Cell. 2008 Feb; 13(2):141-52. PMID: 18242514.
    Citations: 177     Fields:    Translation:AnimalsCells
  29. Pai SY, Kang BY, Sabadini AM, Parisini E, Truitt ML, Ho IC. Distinct structural requirements of GATA-3 for the regulation of thymocyte and Th2 cell differentiation. J Immunol. 2008 Jan 15; 180(2):1050-9. PMID: 18178845.
    Citations: 7     Fields:    Translation:AnimalsCells
  30. Pai, S. Y., B. Y. Kang, A. Sabadini, E. Parisini, M. L. Truitt, and I. C. Ho. Distinct structural requirements of GATA-3 in the regulation of thymocyte and Th2 cell differentiation. The Journal of Immunology. 2008; 180(2):1050-1059.
  31. Moisan J, Grenningloh R, Bettelli E, Oukka M, Ho IC. Ets-1 is a negative regulator of Th17 differentiation. J Exp Med. 2007 Nov 26; 204(12):2825-35. PMID: 17967903.
    Citations: 84     Fields:    Translation:AnimalsCells
  32. Peng S, Lalani S, Leavenworth JW, Ho IC, Pauza ME. c-Maf interacts with c-Myb to down-regulate Bcl-2 expression and increase apoptosis in peripheral CD4 cells. Eur J Immunol. 2007 Oct; 37(10):2868-80. PMID: 17823980.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  33. Ho IC, Pai SY. GATA-3 - not just for Th2 cells anymore. Cell Mol Immunol. 2007 Feb; 4(1):15-29. PMID: 17349208.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  34. Ho IC, Neuzil P, Mraz T, Beldova Z, Gross D, Formanek P, Taborsky M, Niederle P, Ruskin JN, Reddy VY. Use of intracardiac echocardiography to guide implantation of a left atrial appendage occlusion device (PLAATO). Heart Rhythm. 2007 May; 4(5):567-71. PMID: 17467621.
    Citations: 14     Fields:    Translation:Humans
  35. de Guzman Strong C, Wertz PW, Wang C, Yang F, Meltzer PS, Andl T, Millar SE, Ho IC, Pai SY, Segre JA. Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3. J Cell Biol. 2006 Nov 20; 175(4):661-70. PMID: 17116754.
    Citations: 35     Fields:    Translation:AnimalsCells
  36. Kim PJ, Pai SY, Brigl M, Besra GS, Gumperz J, Ho IC. GATA-3 regulates the development and function of invariant NKT cells. J Immunol. 2006 Nov 15; 177(10):6650-9. PMID: 17082577.
    Citations: 56     Fields:    Translation:AnimalsCells
  37. Grenningloh R, Gho A, di Lucia P, Klaus M, Bollag W, Ho IC, Sinigaglia F, Panina-Bordignon P. Cutting Edge: Inhibition of the retinoid X receptor (RXR) blocks T helper 2 differentiation and prevents allergic lung inflammation. J Immunol. 2006 May 01; 176(9):5161-6. PMID: 16621979.
    Citations: 16     Fields:    Translation:AnimalsCells
  38. Kim DC, Hsu FI, Barrett NA, Friend DS, Grenningloh R, Ho IC, Al-Garawi A, Lora JM, Lam BK, Austen KF, Kanaoka Y. Cysteinyl leukotrienes regulate Th2 cell-dependent pulmonary inflammation. J Immunol. 2006 Apr 01; 176(7):4440-8. PMID: 16547282.
    Citations: 53     Fields:    Translation:AnimalsCells
  39. Tanaka S, Fan LW, Tien LT, Park Y, Liu-Chen LY, Rockhold RW, Ho IK. Butorphanol dependence increases hippocampal kappa-opioid receptor gene expression. J Neurosci Res. 2005 Oct 15; 82(2):255-63. PMID: 16130146.
    Citations: 1     Fields:    Translation:AnimalsCells
  40. Zhan Y, Brown C, Maynard E, Anshelevich A, Ni W, Ho IC, Oettgen P. Ets-1 is a critical regulator of Ang II-mediated vascular inflammation and remodeling. J Clin Invest. 2005 Sep; 115(9):2508-16. PMID: 16138193.
    Citations: 90     Fields:    Translation:HumansAnimalsCells
  41. Grenningloh R, Kang BY, Ho IC. Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses. J Exp Med. 2005 Feb 21; 201(4):615-26. PMID: 15728239.
    Citations: 49     Fields:    Translation:AnimalsCells
  42. Kang BY, Miaw SC, Ho IC. ROG negatively regulates T-cell activation but is dispensable for Th-cell differentiation. Mol Cell Biol. 2005 Jan; 25(2):554-62. PMID: 15632058.
    Citations: 15     Fields:    Translation:AnimalsCells
  43. Hausding M, Ho IC, Lehr HA, Weigmann B, Lux C, Schipp M, Galle PR, Finotto S. A stage-specific functional role of the leucine zipper transcription factor c-Maf in lung Th2 cell differentiation. Eur J Immunol. 2004 Dec; 34(12):3401-12. PMID: 15495158.
    Citations: 2     Fields:    Translation:AnimalsCells
  44. Weigmann B, Nemetz A, Becker C, Schmidt J, Strand D, Lehr HA, Galle PR, Ho IC, Neurath MF. A critical regulatory role of leucin zipper transcription factor c-Maf in Th1-mediated experimental colitis. J Immunol. 2004 Sep 01; 173(5):3446-55. PMID: 15322210.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  45. Pai SY, Truitt ML, Ho IC. GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells. Proc Natl Acad Sci U S A. 2004 Feb 17; 101(7):1993-8. PMID: 14769923.
    Citations: 118     Fields:    Translation:AnimalsCells
  46. Miaw SC, Kang BY, White IA, Ho IC. A repressor of GATA-mediated negative feedback mechanism of T cell activation. J Immunol. 2004 Jan 01; 172(1):170-7. PMID: 14688323.
    Citations: 7     Fields:    Translation:AnimalsCells
  47. Pai SY, Truitt ML, Ting CN, Leiden JM, Glimcher LH, Ho IC. Critical roles for transcription factor GATA-3 in thymocyte development. Immunity. 2003 Dec; 19(6):863-75. PMID: 14670303.
    Citations: 126     Fields:    Translation:AnimalsCells
  48. Nurieva RI, Duong J, Kishikawa H, Dianzani U, Rojo JM, Ho Ic, Flavell RA, Dong C. Transcriptional regulation of th2 differentiation by inducible costimulator. Immunity. 2003 Jun; 18(6):801-11. PMID: 12818161.
    Citations: 57     Fields:    Translation:AnimalsCells
  49. Cao S, Liu J, Chesi M, Bergsagel PL, Ho IC, Donnelly RP, Ma X. Differential regulation of IL-12 and IL-10 gene expression in macrophages by the basic leucine zipper transcription factor c-Maf fibrosarcoma. J Immunol. 2002 Nov 15; 169(10):5715-25. PMID: 12421951.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  50. Hwang ES, White IA, Ho IC. An IL-4-independent and CD25-mediated function of c-maf in promoting the production of Th2 cytokines. Proc Natl Acad Sci U S A. 2002 Oct 01; 99(20):13026-30. PMID: 12271139.
    Citations: 22     Fields:    Translation:AnimalsCells
  51. Pai SY, Ho IC. c-Rel delivers a one-two punch in Th1 cell differentiation. J Clin Invest. 2002 Sep; 110(6):741-2. PMID: 12235102.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  52. Hwang ES, Ho IC. Regulation of thymocyte homeostasis by Fliz1. Immunology. 2002 Aug; 106(4):464-9. PMID: 12153508.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  53. Hwang ES, Choi A, Ho IC. Transcriptional regulation of GATA-3 by an intronic regulatory region and fetal liver zinc finger protein 1. J Immunol. 2002 Jul 01; 169(1):248-53. PMID: 12077251.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  54. Ho IC, Glimcher LH. Transcription: tantalizing times for T cells. Cell. 2002 Apr; 109 Suppl:S109-20. PMID: 11983157.
    Citations: 63     Fields:    Translation:HumansAnimalsCells
  55. Kishikawa H, Sun J, Choi A, Miaw SC, Ho IC. The cell type-specific expression of the murine IL-13 gene is regulated by GATA-3. J Immunol. 2001 Oct 15; 167(8):4414-20. PMID: 11591766.
    Citations: 47     Fields:    Translation:AnimalsCells
  56. Ho IC, Arm JP, Bingham CO, Choi A, Austen KF, Glimcher LH. A novel group of phospholipase A2s preferentially expressed in type 2 helper T cells. J Biol Chem. 2001 May 25; 276(21):18321-6. PMID: 11278438.
    Citations: 14     Fields:    Translation:AnimalsCells
  57. Pauza ME, Nguyen A, Wolfe T, Ho IC, Glimcher LH, von Herrath M, Lo D. Variable effects of transgenic c-Maf on autoimmune diabetes. Diabetes. 2001 Jan; 50(1):39-46. PMID: 11147792.
    Citations: 8     Fields:    Translation:AnimalsCells
  58. Miaw SC, Choi A, Yu E, Kishikawa H, Ho IC. ROG, repressor of GATA, regulates the expression of cytokine genes. Immunity. 2000 Mar; 12(3):323-33. PMID: 10755619.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  59. Kim JI, Ho IC, Grusby MJ, Glimcher LH. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity. 1999 Jun; 10(6):745-51. PMID: 10403649.
    Citations: 124     Fields:    Translation:AnimalsCells
  60. Kim JI, Li T, Ho IC, Grusby MJ, Glimcher LH. Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development. Proc Natl Acad Sci U S A. 1999 Mar 30; 96(7):3781-5. PMID: 10097114.
    Citations: 70     Fields:    Translation:AnimalsCells
  61. Ho IC, Kaplan MH, Jackson-Grusby L, Glimcher LH, Grusby MJ. Marking IL-4-producing cells by knock-in of the IL-4 gene. Int Immunol. 1999 Feb; 11(2):243-7. PMID: 10069422.
    Citations: 2     Fields:    Translation:AnimalsCells
  62. Ho IC, Kim JI, Szabo SJ, Glimcher LH. Tissue-specific regulation of cytokine gene expression. Cold Spring Harb Symp Quant Biol. 1999; 64:573-84. PMID: 11232334.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  63. Ho IC, Kim JH, Rooney JW, Spiegelman BM, Glimcher LH. A potential role for the nuclear factor of activated T cells family of transcriptional regulatory proteins in adipogenesis. Proc Natl Acad Sci U S A. 1998 Dec 22; 95(26):15537-41. PMID: 9861004.
    Citations: 25     Fields:    Translation:AnimalsCells
  64. Ho IC, Lo D, Glimcher LH. c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanisms. J Exp Med. 1998 Nov 16; 188(10):1859-66. PMID: 9815263.
    Citations: 87     Fields:    Translation:AnimalsCells
  65. Oukka M, Ho IC, de la Brousse FC, Hoey T, Grusby MJ, Glimcher LH. The transcription factor NFAT4 is involved in the generation and survival of T cells. Immunity. 1998 Sep; 9(3):295-304. PMID: 9768749.
    Citations: 81     Fields:    Translation:AnimalsCells
  66. Szabo SJ, Glimcher LH, Ho IC. Genes that regulate interleukin-4 expression in T cells. Curr Opin Immunol. 1997 Dec; 9(6):776-81. PMID: 9492977.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  67. Ho IC, Hodge MR, Rooney JW, Glimcher LH. The proto-oncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell. 1996 Jun 28; 85(7):973-83. PMID: 8674125.
    Citations: 171     Fields:    Translation:AnimalsCells
  68. Wang CY, Petryniak B, Ho IC, Thompson CB, Leiden JM. Evolutionarily conserved Ets family members display distinct DNA binding specificities. J Exp Med. 1992 May 01; 175(5):1391-9. PMID: 1569404.
    Citations: 70     Fields:    Translation:HumansCells
  69. Thompson CB, Wang CY, Ho IC, Bohjanen PR, Petryniak B, June CH, Miesfeldt S, Zhang L, Nabel GJ, Karpinski B, et al. cis-acting sequences required for inducible interleukin-2 enhancer function bind a novel Ets-related protein, Elf-1. Mol Cell Biol. 1992 Mar; 12(3):1043-53. PMID: 1545787.
    Citations: 86     Fields:    Translation:HumansCells
  70. Ho IC, Vorhees P, Marin N, Oakley BK, Tsai SF, Orkin SH, Leiden JM. Human GATA-3: a lineage-restricted transcription factor that regulates the expression of the T cell receptor alpha gene. EMBO J. 1991 May; 10(5):1187-92. PMID: 1827068.
    Citations: 112     Fields:    Translation:HumansCells
  71. Ho IC, Bhat NK, Gottschalk LR, Lindsten T, Thompson CB, Papas TS, Leiden JM. Sequence-specific binding of human Ets-1 to the T cell receptor alpha gene enhancer. Science. 1990 Nov 09; 250(4982):814-8. PMID: 2237431.
    Citations: 78     Fields:    Translation:HumansCells
  72. Ho IC, Leiden JM. The T alpha 2 nuclear protein binding site from the human T cell receptor alpha enhancer functions as both a T cell-specific transcriptional activator and repressor. J Exp Med. 1990 Nov 01; 172(5):1443-9. PMID: 2230652.
    Citations: 7     Fields:    Translation:HumansCells
  73. Ho IC, Leiden JM. Regulation of the human T-cell receptor alpha gene enhancer: multiple ubiquitous and T-cell-specific nuclear proteins interact with four hypomethylated enhancer elements. Mol Cell Biol. 1990 Sep; 10(9):4720-7. PMID: 2388624.
    Citations: 23     Fields:    Translation:HumansCells
  74. Ho IC, Yang LH, Morle G, Leiden JM. A T-cell-specific transcriptional enhancer element 3' of C alpha in the human T-cell receptor alpha locus. Proc Natl Acad Sci U S A. 1989 Sep; 86(17):6714-8. PMID: 2788889.
    Citations: 63     Fields:    Translation:HumansCells
  75. Tsai IK, Yen MY, Ho IC, Yu KW, Liu CY, Cheng DL. Clostridium perfringens septicemia with massive hemolysis. Scand J Infect Dis. 1989; 21(4):467-71. PMID: 2555910.
    Citations: 4     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.