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Chester Allan Alper, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI035630 (ALPER, CHESTER ALLAN) Sep 30, 1995 - Jul 31, 1999
    NIH/NIAID
    NONREPONSE TO THE HEPATITIS B VACCINE
    Role: Principal Investigator
  2. S15CA053688 (ALPER, CHESTER ALLAN) Aug 1, 1990 - Jul 31, 1992
    NIH/NCI
    SMALL INSTRUMENTATION GRANT
    Role: Principal Investigator
  3. S15HL043990 (ALPER, CHESTER ALLAN) Sep 1, 1989 - Aug 31, 1991
    NIH/NHLBI
    SMALL INSTRUMENTATION PROGRAM
    Role: Principal Investigator
  4. S10RR004828 (ALPER, CHESTER ALLAN) Apr 24, 1989 - Apr 23, 1990
    NIH/NCRR
    DNA SYNTHESIZER/SEQUENCING SYSTEM
    Role: Principal Investigator
  5. S15HL041723 (ALPER, CHESTER ALLAN) Jun 1, 1988 - May 31, 1989
    NIH/NHLBI
    LASER DENSITOMETER--ISOCRATIC TITANIUM FLUID PATH SYSTEM
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Vadva Z, Larsen CE, Propp BE, Trautwein MR, Alford DR, Alper CA. A New Pedigree-Based SNP Haplotype Method for Genomic Polymorphism and Genetic Studies. Cells. 2019 08 05; 8(8). PMID: 31387299.
    Citations:    
  2. Alper CA, Larsen CE, Trautwein MR, Alford DR. A stochastic epigenetic Mendelian oligogenic disease model for type 1 diabetes. J Autoimmun. 2019 01; 96:123-133. PMID: 30309752.
    Citations:    Fields:    
  3. Alper CA, Larsen CE. Pedigree-Defined Haplotypes and Their Applications to Genetic Studies. Methods Mol Biol. 2017; 1551:113-127. PMID: 28138843.
    Citations:    Fields:    Translation:Humans
  4. Larsen CE, Alford DR, Trautwein MR, Jalloh YK, Tarnacki JL, Kunnenkeri SK, Fici DA, Yunis EJ, Awdeh ZL, Alper CA. Dominant sequences of human major histocompatibility complex conserved extended haplotypes from HLA-DQA2 to DAXX. PLoS Genet. 2014 Oct; 10(10):e1004637. PMID: 25299700.
    Citations: 6     Fields:    Translation:HumansCells
  5. Granados-Montiel J, Zúñiga J, Azocar J, Feris EJ, Terreros D, Larsen CE, Clavijo OP, Cruz-Lagunas A, Middleton D, Alper CA, Pandey JP, Yunis EJ. Interaction between immunoglobulin allotypes and NK receptor genes in diabetes post-hepatitis C virus infection. Immunobiology. 2011 Jun; 216(6):686-91. PMID: 21281981.
    Citations:    Fields:    Translation:HumansCells
  6. Szilágyi A, Bánlaki Z, Pozsonyi E, Yunis EJ, Awdeh ZL, Hossó A, Rajczy K, Larsen CE, Fici DA, Alper CA, Füst G. Frequent occurrence of conserved extended haplotypes (CEHs) in two Caucasian populations. Mol Immunol. 2010 Jun; 47(10):1899-904. PMID: 20409590.
    Citations: 3     Fields:    Translation:HumansCells
  7. Zúñiga J, Romero V, Azocar J, Terreros D, Vargas-Rojas MI, Torres-García D, Jiménez-Alvarez L, Vargas-Alarcón G, Granados-Montiel J, Husain Z, Chung RT, Alper CA, Yunis EJ. Protective KIR-HLA interactions for HCV infection in intravenous drug users. Mol Immunol. 2009 Aug; 46(13):2723-7. PMID: 19552960.
    Citations: 9     Fields:    Translation:Humans
  8. Husain Z, Kelly MA, Eisenbarth GS, Pugliese A, Awdeh ZL, Larsen CE, Alper CA. The MHC type 1 diabetes susceptibility gene is centromeric to HLA-DQB1. J Autoimmun. 2008 Jun; 30(4):266-72. PMID: 18065200.
    Citations: 7     Fields:    Translation:HumansCells
  9. Romero V, Larsen CE, Duke-Cohan JS, Fox EA, Romero T, Clavijo OP, Fici DA, Husain Z, Almeciga I, Alford DR, Awdeh ZL, Zuñiga J, El-Dahdah L, Alper CA, Yunis EJ. Genetic fixity in the human major histocompatibility complex and block size diversity in the class I region including HLA-E. BMC Genet. 2007 Apr 12; 8:14. PMID: 17430593.
    Citations: 9     Fields:    Translation:HumansCells
  10. Awdeh ZL, Yunis EJ, Audeh MJ, Fici D, Pugliese A, Larsen CE, Alper CA. A genetic explanation for the rising incidence of type 1 diabetes, a polygenic disease. J Autoimmun. 2006 Nov; 27(3):174-81. PMID: 17052889.
    Citations: 6     Fields:    Translation:HumansCells
  11. Alper CA, Husain Z, Larsen CE, Dubey DP, Stein R, Day C, Baker A, Beyan H, Hawa M, Ola TO, Leslie RD. Incomplete penetrance of susceptibility genes for MHC-determined immunoglobulin deficiencies in monozygotic twins discordant for type 1 diabetes. J Autoimmun. 2006 Sep; 27(2):89-95. PMID: 17029885.
    Citations: 9     Fields:    Translation:Humans
  12. Bilbao JR, Calvo B, Aransay AM, Martin-Pagola A, Perez de Nanclares G, Aly TA, Rica I, Vitoria JC, Gaztambide S, Noble J, Fain PR, Awdeh ZL, Alper CA, Castaño L. Conserved extended haplotypes discriminate HLA-DR3-homozygous Basque patients with type 1 diabetes mellitus and celiac disease. Genes Immun. 2006 Oct; 7(7):550-4. PMID: 16929349.
    Citations: 12     Fields:    Translation:Humans
  13. Husain Z, Holodick N, Day C, Szymanski I, Alper CA. Increased apoptosis of CD20+ IgA + B cells is the basis for IgA deficiency: the molecular mechanism for correction in vitro by IL-10 and CD40L. J Clin Immunol. 2006 Mar; 26(2):113-25. PMID: 16758339.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  14. Alper CA, Larsen CE, Dubey DP, Awdeh ZL, Fici DA, Yunis EJ. The haplotype structure of the human major histocompatibility complex. Hum Immunol. 2006 Jan-Feb; 67(1-2):73-84. PMID: 16698428.
    Citations: 32     Fields:    Translation:Humans
  15. Awdeh ZL, Alper CA. Mendelian inheritance of polygenic diseases: a hypothetical basis for increasing incidence. Med Hypotheses. 2005; 64(3):495-8. PMID: 15617855.
    Citations:    Fields:    Translation:Humans
  16. Larsen CE, Alper CA. The genetics of HLA-associated disease. Curr Opin Immunol. 2004 Oct; 16(5):660-7. PMID: 15342014.
    Citations: 27     Fields:    Translation:HumansAnimals
  17. Pinto C, Smith AG, Larsen CE, Fernández-Viña M, Husain Z, Clavijo OP, Wang ZC, Nisperos B, Hansen JA, Alper CA, Yunis EJ. HLA-Cw*0409N is associated with HLA-A*2301 and HLA-B*4403-carrying haplotypes. Hum Immunol. 2004 Feb; 65(2):181-7. PMID: 14969773.
    Citations: 4     Fields:    Translation:HumansCells
  18. Yunis EJ, Larsen CE, Fernandez-Viña M, Awdeh ZL, Romero T, Hansen JA, Alper CA. Inheritable variable sizes of DNA stretches in the human MHC: conserved extended haplotypes and their fragments or blocks. Tissue Antigens. 2003 Jul; 62(1):1-20. PMID: 12859592.
    Citations: 44     Fields:    Translation:HumansCells
  19. Alper CA, Xu J, Cosmopoulos K, Dolinski B, Stein R, Uko G, Larsen CE, Dubey DP, Densen P, Truedsson L, Sturfelt G, Sjöholm AG. Immunoglobulin deficiencies and susceptibility to infection among homozygotes and heterozygotes for C2 deficiency. J Clin Immunol. 2003 Jul; 23(4):297-305. PMID: 12959222.
    Citations: 7     Fields:    Translation:Humans
  20. Crawford K, Stark A, Kitchens B, Sternheim K, Pantazopoulos V, Triantafellow E, Wang Z, Vasir B, Larsen CE, Gabuzda D, Reinherz E, Alper CA. CD2 engagement induces dendritic cell activation: implications for immune surveillance and T-cell activation. Blood. 2003 Sep 01; 102(5):1745-52. PMID: 12714509.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  21. Alper CA, Kevy SV, Konugres AA. Louis K. Diamond. Transfusion. 2002 Oct; 42(10):1381-2. PMID: 12449155.
    Citations:    Fields:    
  22. Husain Z, Alper CA, Yunis EJ, Dubey DP. Complex expression of natural killer receptor genes in single natural killer cells. Immunology. 2002 Jul; 106(3):373-80. PMID: 12100725.
    Citations: 8     Fields:    Translation:HumansCells
  23. Husain Z, Levitan E, Larsen CE, Mirza NM, Younes S, Yunis EJ, Alper CA, Dubey DP. HLA-Cw7 zygosity affects the size of a subset of CD158b+ natural killer cells. J Clin Immunol. 2002 Jan; 22(1):28-36. PMID: 11958591.
    Citations: 7     Fields:    Translation:HumansCells
  24. Uko GP, Fraser PA, Awdeh ZL, Fici DA, Crawford KD, Larsen CE, Alper CA. Hepatitis B surface antigen- and tetanus toxoid-specific clonal expansion of CD4+ cells in vitro determined by TCRBV CDR3 length and nucleotide sequence. Genes Immun. 2001 Feb; 2(1):11-9. PMID: 11294562.
    Citations: 1     Fields:    Translation:HumansCells
  25. Alper CA, Marcus-Bagley D, Awdeh Z, Kruskall MS, Eisenbarth GS, Brink SJ, Katz AJ, Stein R, Bing DH, Yunis EJ, Schur PH. Prospective analysis suggests susceptibility genes for deficiencies of IgA and several other immunoglobulins on the [HLA-B8, SC01, DR3] conserved extended haplotype. Tissue Antigens. 2000 Sep; 56(3):207-16. PMID: 11034556.
    Citations: 16     Fields:    Translation:HumansCells
  26. Alper CA, Awdeh Z. Incomplete penetrance of MHC susceptibility genes: prospective analysis of polygenic MHC-determined traits. Tissue Antigens. 2000 Sep; 56(3):199-206. PMID: 11034555.
    Citations: 2     Fields:    Translation:Humans
  27. Larsen CE, Xu J, Lee S, Dubey DP, Uko G, Yunis EJ, Alper CA. Complex cytokine responses to hepatitis B surface antigen and tetanus toxoid in responders, nonresponders and subjects naive to hepatitis B surface antigen. Vaccine. 2000 Jul 01; 18(26):3021-30. PMID: 10825606.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  28. Calvo B, Castaño L, Marcus-Bagley D, Fici DA, Awdeh Z, Alper CA. The [HLA-B18, F1C30, DR3] conserved extended haplotype carries a susceptibility gene for IgD deficiency. J Clin Immunol. 2000 May; 20(3):216-20. PMID: 10941830.
    Citations: 3     Fields:    Translation:Humans
  29. Alper CA, Dubey DP, Yunis EJ, Awdeh Z. A simple estimate of the general population frequency of the MHC susceptibility gene for autoimmune polygenic disease. Exp Clin Immunogenet. 2000; 17(3):138-47. PMID: 10899739.
    Citations:    Fields:    Translation:Humans
  30. Crawford K, Alper CA. Genetics of the complement system. Rev Immunogenet. 2000; 2(3):323-38. PMID: 11256743.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  31. Crawford K, Gabuzda D, Pantazopoulos V, Xu J, Clement C, Reinherz E, Alper CA. Circulating CD2+ monocytes are dendritic cells. J Immunol. 1999 Dec 01; 163(11):5920-8. PMID: 10570278.
    Citations: 12     Fields:    Translation:HumansCells
  32. Wang Z, Yunis D, Irigoyen M, Kitchens B, Bottaro A, Alt FW, Alper CA. Discordance between IgA switching at the DNA level and IgA expression at the mRNA level in IgA-deficient patients. Clin Immunol. 1999 Jun; 91(3):263-70. PMID: 10370371.
    Citations: 10     Fields:    Translation:HumansCells
  33. Fredrikson GN, Gullstrand B, Schneider PM, Witzel-Schlömp K, Sjöholm AG, Alper CA, Awdeh Z, Truedsson L. Characterization of non-expressed C4 genes in a case of complete C4 deficiency: identification of a novel point mutation leading to a premature stop codon. Hum Immunol. 1998 Nov; 59(11):713-9. PMID: 9796739.
    Citations: 5     Fields:    Translation:HumansCells
  34. Clavijo OP, Delgado JC, Awdeh ZL, Fici D, Turbay D, Alper CA, Truedsson L, Yunis EJ. HLA-Cw alleles associated with HLA extended haplotypes and C2 deficiency. Tissue Antigens. 1998 Sep; 52(3):282-5. PMID: 9802610.
    Citations: 2     Fields:    Translation:Humans
  35. Alper CA. A history of complement genetics. Exp Clin Immunogenet. 1998; 15(4):203-12. PMID: 10072630.
    Citations: 1     Fields:    Translation:HumansAnimals
  36. Chedid MG, Deulofeut H, Yunis DE, Lara-Marquez ML, Salazar M, Deulofeut R, Awdeh Z, Alper CA, Yunis EJ. Defect in Th1-like cells of nonresponders to hepatitis B vaccine. Hum Immunol. 1997 Nov; 58(1):42-51. PMID: 9438208.
    Citations: 14     Fields:    Translation:HumansCells
  37. Delgado JC, Hameed A, Yunis JJ, Bhol K, Rojas AI, Rehman SB, Khan AA, Ahmad M, Alper CA, Ahmed AR, Yunis EJ. Pemphigus vulgaris autoantibody response is linked to HLA-DQB1*0503 in Pakistani patients. Hum Immunol. 1997 Oct; 57(2):110-9. PMID: 9438202.
    Citations: 6     Fields:    Translation:HumansCells
  38. Mobini N, Yunis EJ, Alper CA, Yunis JJ, Delgado JC, Yunis DE, Firooz A, Dowlati Y, Bahar K, Gregersen PK, Ahmed AR. Identical MHC markers in non-Jewish Iranian and Ashkenazi Jewish patients with pemphigus vulgaris: possible common central Asian ancestral origin. Hum Immunol. 1997 Sep 15; 57(1):62-7. PMID: 9438197.
    Citations: 5     Fields:    Translation:Humans
  39. Simon S, Truedsson L, Marcus-Bagley D, Awdeh Z, Eisenbarth GS, Brink SJ, Yunis EJ, Alper CA. Relationship between protein complotypes and DNA variant haplotypes: complotype-RFLP constellations (CRC). Hum Immunol. 1997 Sep 15; 57(1):27-36. PMID: 9438192.
    Citations: 2     Fields:    Translation:Humans
  40. Turbay D, Lieberman J, Alper CA, Delgado JC, Corzo D, Yunis JJ, Yunis EJ. Tumor necrosis factor constellation polymorphism and clozapine-induced agranulocytosis in two different ethnic groups. Blood. 1997 Jun 01; 89(11):4167-74. PMID: 9166860.
    Citations: 14     Fields:    Translation:Humans
  41. Delgado JC, Yunis DE, Bozón MV, Salazar M, Deulofeut R, Turbay D, Mehra NK, Pasricha JS, Raval RS, Patel H, Shah BK, Bhol K, Alper CA, Ahmed AR, Yunis EJ. MHC class II alleles and haplotypes in patients with pemphigus vulgaris from India. Tissue Antigens. 1996 Dec; 48(6):668-72. PMID: 9008309.
    Citations: 4     Fields:    Translation:Humans
  42. Garcia-Merino A, Alper CA, Usuku K, Marcus-Bagley D, Lincoln R, Awdeh Z, Yunis EJ, Eisenbarth GS, Brink SJ, Hauser SL. Tumor necrosis factor (TNF) microsatellite haplotypes in relation to extended haplotypes, susceptibility to diseases associated with the major histocompatibility complex and TNF secretion. Hum Immunol. 1996 Sep 15; 50(1):11-21. PMID: 8872171.
    Citations: 4     Fields:    Translation:HumansCells
  43. Delgado JC, Turbay D, Yunis EJ, Yunis JJ, Morton ED, Bhol K, Norman R, Alper CA, Good RA, Ahmed R. A common major histocompatibility complex class II allele HLA-DQB1* 0301 is present in clinical variants of pemphigoid. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8569-71. PMID: 8710911.
    Citations: 17     Fields:    Translation:HumansCells
  44. Fraser PA, Yunis EJ, Alper CA. Excess admixture proportion of extended major histocompatability complex haplotypes of Caucasian origin among rheumatoid arthritis associated haplotypes in African Americans and Afro-Caribbeans. Ethn Health. 1996 May; 1(2):153-9. PMID: 9395559.
    Citations: 1     Fields:    Translation:Humans
  45. Pugliese A, Awdeh ZL, Alper CA, Jackson RA, Eisenbarth GS. The INS B allele (1,428 Fok I) is associated with reduced IDDM incidence in autoantibody-positive first degree relatives despite the presence of autoantibodies and high-risk HLA alleles. Transplant Proc. 1995 Dec; 27(6):3392. PMID: 8540014.
    Citations: 1     Fields:    Translation:Humans
  46. Corzo D, Yunis JJ, Salazar M, Lieberman JA, Howard A, Awdeh Z, Alper CA, Yunis EJ. The major histocompatibility complex region marked by HSP70-1 and HSP70-2 variants is associated with clozapine-induced agranulocytosis in two different ethnic groups. Blood. 1995 Nov 15; 86(10):3835-40. PMID: 7579351.
    Citations: 9     Fields:    Translation:Humans
  47. Awdeh ZL, Alper CA, Fici DA, Ronco P, Yunis EJ. Predictability of alloreactivity among unrelated individuals: role for HLA-DPB1. Tissue Antigens. 1995 Sep; 46(3 ( Pt 1)):180-6. PMID: 8525477.
    Citations:    Fields:    Translation:HumansCells
  48. Pugliese A, Gianani R, Moromisato R, Awdeh ZL, Alper CA, Erlich HA, Jackson RA, Eisenbarth GS. HLA-DQB1*0602 is associated with dominant protection from diabetes even among islet cell antibody-positive first-degree relatives of patients with IDDM. Diabetes. 1995 Jun; 44(6):608-13. PMID: 7789622.
    Citations: 38     Fields:    Translation:Humans
  49. Alper CA. The human immune response to hepatitis B surface antigen. Exp Clin Immunogenet. 1995; 12(3):171-81. PMID: 8534503.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  50. Weiss RE, Sunthornthepvarakul T, Angkeow P, Marcus-Bagley D, Cox N, Alper CA, Refetoff S. Linkage of familial dysalbuminemic hyperthyroxinemia to the albumin gene in a large Amish kindred. J Clin Endocrinol Metab. 1995 Jan; 80(1):116-21. PMID: 7829599.
    Citations: 3     Fields:    Translation:HumansCells
  51. Salazar M, Deulofeut H, Granja C, Deulofeut R, Yunis DE, Marcus-Bagley D, Awdeh Z, Alper CA, Yunis EJ. Normal HBsAg presentation and T-cell defect in the immune response of nonresponders. Immunogenetics. 1995; 41(6):366-74. PMID: 7759133.
    Citations: 9     Fields:    Translation:HumansCells
  52. Gibson WT, Walter MA, Ahmed AR, Alper CA, Cox DW. The immunoglobulin heavy chain and disease association: application to pemphigus vulgaris. Hum Genet. 1994 Dec; 94(6):675-83. PMID: 7989043.
    Citations: 2     Fields:    Translation:Humans
  53. Pugliese A, Awdeh ZL, Alper CA, Jackson RA, Eisenbarth GS. The paternally inherited insulin gene B allele (1,428 FokI site) confers protection from insulin-dependent diabetes in families. J Autoimmun. 1994 Oct; 7(5):687-94. PMID: 7840860.
    Citations: 8     Fields:    Translation:Humans
  54. Yunis JJ, Mobini N, Yunis EJ, Alper CA, Deulofeut R, Rodriguez A, Foster CS, Marcus-Bagley D, Good RA, Ahmed AR. Common major histocompatibility complex class II markers in clinical variants of cicatricial pemphigoid. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7747-51. PMID: 8052655.
    Citations: 6     Fields:    Translation:HumansCells
  55. Pugliese A, Bugawan T, Moromisato R, Awdeh ZL, Alper CA, Jackson RA, Erlich HA, Eisenbarth GS. Two subsets of HLA-DQA1 alleles mark phenotypic variation in levels of insulin autoantibodies in first degree relatives at risk for insulin-dependent diabetes. J Clin Invest. 1994 Jun; 93(6):2447-52. PMID: 8200980.
    Citations: 7     Fields:    Translation:HumansCells
  56. Dubey DP, Alper CA, Mirza NM, Awdeh Z, Yunis EJ. Polymorphic Hh genes in the HLA-B(C) region control natural killer cell frequency and activity. J Exp Med. 1994 Apr 01; 179(4):1193-203. PMID: 8145038.
    Citations: 5     Fields:    Translation:HumansCells
  57. Pugliese A, Solimena M, Awdeh ZL, Alper CA, Bugawan T, Erlich HA, De Camilli P, Eisenbarth GS. Association of HLA-DQB1*0201 with stiff-man syndrome. J Clin Endocrinol Metab. 1993 Dec; 77(6):1550-3. PMID: 8263140.
    Citations: 6     Fields:    Translation:Humans
  58. Ahmed AR, Yunis JJ, Marcus-Bagley D, Yunis EJ, Salazar M, Katz AJ, Awdeh Z, Alper CA. Major histocompatibility complex susceptibility genes for dermatitis herpetiformis compared with those for gluten-sensitive enteropathy. J Exp Med. 1993 Dec 01; 178(6):2067-75. PMID: 8245782.
    Citations: 3     Fields:    Translation:Humans
  59. Truedsson L, Alper CA, Awdeh ZL, Johansen P, Sjöholm AG, Sturfelt G. Characterization of type I complement C2 deficiency MHC haplotypes. Strong conservation of the complotype/HLA-B-region and absence of disease association due to linked class II genes. J Immunol. 1993 Nov 15; 151(10):5856-63. PMID: 7901282.
    Citations: 8     Fields:    Translation:HumansCells
  60. Cascino I, D'Alfonso S, Cappello N, Giordano M, Pugliese A, Awdeh Z, Alper CA, Richiardi PM. Gametic association of HSP70-1 promoter region alleles and their inclusion in extended HLA haplotypes. Tissue Antigens. 1993 Aug; 42(2):62-6. PMID: 7903489.
    Citations: 4     Fields:    Translation:HumansCells
  61. Deulofeut H, Iglesias A, Mikael N, Bing DH, Awdeh Z, Yunis J, Marcus-Bagley D, Kruskall MS, Alper CA, Yunis EJ. Cellular recognition and HLA restriction of a midsequence HBsAg peptide in hepatitis B vaccinated individuals. Mol Immunol. 1993 Jul; 30(10):941-8. PMID: 8341285.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  62. Ahmed AR, Mohimen A, Yunis EJ, Mirza NM, Kumar V, Beutner EH, Alper CA. Linkage of pemphigus vulgaris antibody to the major histocompatibility complex in healthy relatives of patients. J Exp Med. 1993 Feb 01; 177(2):419-24. PMID: 8426112.
    Citations: 8     Fields:    Translation:Humans
  63. Yunis JJ, Salazar M, Delgado MB, Alper CA, Bing DH, Yunis EJ. HLA-DQA1, DQB1 and DPB1 alleles on HLA-DQ2- and DQ9-carrying extended haplotypes. Tissue Antigens. 1993 Jan; 41(1):37-41. PMID: 8096094.
    Citations: 3     Fields:    Translation:HumansCells
  64. Usuku K, Joshi N, Hatem CJ, Alper CA, Schoenfeld DA, Hauser SL. The human T-cell receptor beta-chain repertoire: longitudinal fluctuations and assessment in MHC matched populations. Immunogenetics. 1993; 38(3):193-8. PMID: 8099343.
    Citations: 2     Fields:    Translation:HumansCells
  65. Pugliese A, Awdeh ZL, Galluzzo A, Yunis EJ, Alper CA, Eisenbarth GS. No independent association between HSP70 gene polymorphism and IDDM. Diabetes. 1992 Jul; 41(7):788-91. PMID: 1351854.
    Citations: 9     Fields:    Translation:HumansCells
  66. Gianani R, Pugliese A, Bonner-Weir S, Shiffrin AJ, Soeldner JS, Erlich H, Awdeh Z, Alper CA, Jackson RA, Eisenbarth GS. Prognostically significant heterogeneity of cytoplasmic islet cell antibodies in relatives of patients with type I diabetes. Diabetes. 1992 Mar; 41(3):347-53. PMID: 1551494.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  67. Awdeh ZL, Alper CA, Fici D, Eynon E, Bishara A, Yunis EJ. Predictability of alloreactivity among unrelated individuals. Tissue Antigens. 1992 Feb; 39(2):51-7. PMID: 1574798.
    Citations:    Fields:    Translation:HumansCells
  68. Kruskall MS, Alper CA, Awdeh Z, Yunis EJ, Marcus-Bagley D. The immune response to hepatitis B vaccine in humans: inheritance patterns in families. J Exp Med. 1992 Feb 01; 175(2):495-502. PMID: 1531063.
    Citations: 21     Fields:    Translation:Humans
  69. Blumenthal M, Marcus-Bagley D, Awdeh Z, Johnson B, Yunis EJ, Alper CA. HLA-DR2, [HLA-B7, SC31, DR2], and [HLA-B8, SC01, DR3] haplotypes distinguish subjects with asthma from those with rhinitis only in ragweed pollen allergy. J Immunol. 1992 Jan 15; 148(2):411-6. PMID: 1729361.
    Citations: 5     Fields:    Translation:Humans
  70. Alper CA, Awdeh Z, Yunis EJ. Conserved, extended MHC haplotypes. Exp Clin Immunogenet. 1992; 9(2):58-71. PMID: 1489551.
    Citations: 9     Fields:    Translation:HumansCells
  71. Ahmed AR, Foster S, Zaltas M, Notani G, Awdeh Z, Alper CA, Yunis EJ. Association of DQw7 (DQB1*0301) with ocular cicatricial pemphigoid. Proc Natl Acad Sci U S A. 1991 Dec 15; 88(24):11579-82. PMID: 1763074.
    Citations: 11     Fields:    Translation:Humans
  72. Simon S, Awdeh Z, Campbell RD, Ronco P, Brink SJ, Eisenbarth GS, Yunis EJ, Alper CA. A restriction fragment of the C2 gene is a unique marker for C2 deficiency and the uncommon C2 allele C2*B (a marker for type 1 diabetes). J Clin Invest. 1991 Dec; 88(6):2142-5. PMID: 1684365.
    Citations:    Fields:    Translation:Humans
  73. Ahmed AR, Wagner R, Khatri K, Notani G, Awdeh Z, Alper CA, Yunis EJ. Major histocompatibility complex haplotypes and class II genes in non-Jewish patients with pemphigus vulgaris. Proc Natl Acad Sci U S A. 1991 Jun 01; 88(11):5056-60. PMID: 1675792.
    Citations: 21     Fields:    Translation:Humans
  74. Ziegler R, Alper CA, Awdeh ZL, Castano L, Brink SJ, Soeldner JS, Jackson RA, Eisenbarth GS. Specific association of HLA-DR4 with increased prevalence and level of insulin autoantibodies in first-degree relatives of patients with type I diabetes. Diabetes. 1991 Jun; 40(6):709-14. PMID: 2040387.
    Citations: 12     Fields:    Translation:Humans
  75. Varga L, Alper CA, Zam Z, Füst G. Decreased inhibition of immune precipitation by sera with the C2 B allotype. Clin Immunol Immunopathol. 1991 Apr; 59(1):65-71. PMID: 2019011.
    Citations:    Fields:    Translation:Humans
  76. Erlich HA, Griffith RL, Bugawan TL, Ziegler R, Alper C, Eisenbarth G. Implication of specific DQB1 alleles in genetic susceptibility and resistance by identification of IDDM siblings with novel HLA-DQB1 allele and unusual DR2 and DR1 haplotypes. Diabetes. 1991 Apr; 40(4):478-81. PMID: 2010048.
    Citations: 19     Fields:    Translation:HumansCells
  77. Egea E, Iglesias A, Salazar M, Morimoto C, Kruskall MS, Awdeh Z, Schlossman SF, Alper CA, Yunis EJ. The cellular basis for lack of antibody response to hepatitis B vaccine in humans. J Exp Med. 1991 Mar 01; 173(3):531-8. PMID: 1825504.
    Citations: 21     Fields:    Translation:HumansCells
  78. Egea GE, Yunis I, Spies T, Strominger J, Awdeh ZL, Alper CA, Yunis EJ. Association of polymorphisms in the HLA-B region with extended haplotypes. Immunogenetics. 1991; 33(1):4-11. PMID: 1671666.
    Citations: 2     Fields:    Translation:Humans
  79. Fraser PA, Awdeh ZL, Ronco P, Simon S, Moore B, Fici D, Marcus-Bagley D, Yunis EJ, Alper CA. C4B gene polymorphisms among African and African-American HLA-Bw42-DRw18 haplotypes. Immunogenetics. 1991; 34(1):52-6. PMID: 1677346.
    Citations:    Fields:    Translation:Humans
  80. Ahmed AR, Yunis EJ, Khatri K, Wagner R, Notani G, Awdeh Z, Alper CA. Major histocompatibility complex haplotype studies in Ashkenazi Jewish patients with pemphigus vulgaris. Proc Natl Acad Sci U S A. 1990 Oct; 87(19):7658-62. PMID: 2217197.
    Citations: 30     Fields:    Translation:Humans
  81. Fronek Z, Timmerman LA, Alper CA, Hahn BH, Kalunian K, Peterlin BM, McDevitt HO. Major histocompatibility complex genes and susceptibility to systemic lupus erythematosus. Arthritis Rheum. 1990 Oct; 33(10):1542-53. PMID: 1977392.
    Citations: 20     Fields:    Translation:Humans
  82. Schur PH, Marcus-Bagley D, Awdeh Z, Yunis EJ, Alper CA. The effect of ethnicity on major histocompatibility complex complement allotypes and extended haplotypes in patients with systemic lupus erythematosus. Arthritis Rheum. 1990 Jul; 33(7):985-92. PMID: 2369433.
    Citations: 13     Fields:    Translation:Humans
  83. Ahmed AR, Yunis EJ, Alper CA. Complotypes in pemphigus vulgaris: differences between Jewish and non-Jewish patients. Hum Immunol. 1990 Apr; 27(4):298-304. PMID: 2318675.
    Citations: 3     Fields:    Translation:Humans
  84. Fraser PA, Stern S, Larson MG, Marcus-Bagley D, Awdeh Z, Glass DN, Alper CA. HLA extended haplotypes in childhood and adult onset HLA-DR4-associated arthropathies. Tissue Antigens. 1990 Feb; 35(2):56-9. PMID: 2343452.
    Citations: 2     Fields:    Translation:Humans
  85. Yunis JJ, Wescott M, Lechin SJ, Alosco SM, Awdeh Z, Alper CA, Yunis EJ. HLA-DQ RFLP variants of five HLA-DQw2-bearing major histocompatibility complex extended haplotypes. Immunogenetics. 1990; 32(2):88-95. PMID: 1975800.
    Citations:    Fields:    Translation:Humans
  86. Mauff G, Alper CA, Dawkins R, Doxiadis G, Giles CM, Hauptmann G, Rittner C, Schneider PM. C4 nomenclature statement (1990). Complement Inflamm. 1990; 7(4-6):261-8. PMID: 2088664.
    Citations: 3     Fields:    Translation:Humans
  87. Fraser PA, Moore B, Stein R, Alosco S, Johnson AH, Marcus-Bagley D, Awdeh Z, Yunis EJ, Alper CA. Complotypes in individuals of African origin: frequencies and possible extended MHC haplotypes. Immunogenetics. 1990; 31(2):89-93. PMID: 2303279.
    Citations: 3     Fields:    Translation:Humans
  88. Kruskall MS, Yunis EJ, Watson A, Awdeh Z, Alper CA. Major histocompatibility complex markers and red cell antibodies to the Rh (D) antigen. Absence of association. Transfusion. 1990 Jan; 30(1):15-9. PMID: 2104997.
    Citations: 1     Fields:    Translation:Humans
  89. Mitus AJ, Stein R, Rappeport JM, Antin JH, Weinstein HJ, Alper CA, Smith BR. Monoclonal and oligoclonal gammopathy after bone marrow transplantation. Blood. 1989 Dec; 74(8):2764-8. PMID: 2819246.
    Citations: 14     Fields:    Translation:HumansCells
  90. Alper CA, Kruskall MS, Marcus-Bagley D, Craven DE, Katz AJ, Brink SJ, Dienstag JL, Awdeh Z, Yunis EJ. Genetic prediction of nonresponse to hepatitis B vaccine. N Engl J Med. 1989 Sep 14; 321(11):708-12. PMID: 2528067.
    Citations: 63     Fields:    Translation:Humans
  91. Hauser SL, Fleischnick E, Weiner HL, Marcus D, Awdeh Z, Yunis EJ, Alper CA. Extended major histocompatibility complex haplotypes in patients with multiple sclerosis. Neurology. 1989 Feb; 39(2 Pt 1):275-7. PMID: 2783768.
    Citations: 14     Fields:    Translation:Humans
  92. Alper CA, Awdeh ZL, Yunis EJ. Complotypes and extended haplotypes in laboratory medicine. Complement Inflamm. 1989; 6(1):8-18. PMID: 2650992.
    Citations: 9     Fields:    Translation:HumansCells
  93. Truedsson L, Awdeh Z, Yunis EJ, Mrose S, Moore B, Alper CA. Quantitative variation of C4 variant proteins associated with many MHC haplotypes. Immunogenetics. 1989; 30(6):414-21. PMID: 2574157.
    Citations: 7     Fields:    Translation:Humans
  94. Fronek Z, Timmerman LA, Alper CA, Hahn BH, Kalunian K, Peterlin BM, McDevitt HO. Major histocompatibility complex associations with systemic lupus erythematosus. Am J Med. 1988 Dec 23; 85(6A):42-4. PMID: 2904762.
    Citations: 11     Fields:    Translation:Humans
  95. Dasgupta JD, Relias V, Awdeh ZL, Alper CA, Yunis EJ. Two variants of DRw52, DR3, and DQw2 specificities distinguish two different DR3-bearing extended haplotypes. Hum Immunol. 1988 Feb; 21(2):133-42. PMID: 2835344.
    Citations: 6     Fields:    Translation:HumansCells
  96. Hayes DF, Sekine H, Marcus D, Alper CA, Kufe DW. Genetically determined polymorphism of the circulating human breast cancer-associated DF3 antigen. Blood. 1988 Feb; 71(2):436-40. PMID: 3337905.
    Citations: 2     Fields:    Translation:Humans
  97. Sklarin PM, Awdeh ZL, Alper CA. An immunoblotting technique for direct visualization of Chido and Rodgers reactivity on C4 variants after electrophoresis. Vox Sang. 1988; 54(1):43-6. PMID: 2450426.
    Citations:    Fields:    Translation:Humans
  98. Whitehead AS, Truedsson L, Schneider PM, Awdeh ZL, Fleischnick E, Blumenthal M, Costello W, Gerald PS, Yunis EJ, Alper CA. The distribution of human C4 DNA variants in relation to major histocompatibility complex alleles and extended haplotypes. Hum Immunol. 1988 Jan; 21(1):23-32. PMID: 3163333.
    Citations: 5     Fields:    Translation:Humans
  99. Wisnieski JJ, Nathanson MH, Anderson JE, Davis AE, Alper CA, Naff GB. Metabolism of C4 and linkage analysis in a kindred with hereditary incomplete C4 deficiency. Arthritis Rheum. 1987 Aug; 30(8):919-26. PMID: 3477232.
    Citations: 1     Fields:    Translation:Humans
  100. Boustany RM, Fleischnick E, Alper CA, Marazita ML, Spence MA, Martin JB, Kolodny EH. The autosomal dominant form of "pure" familial spastic paraplegia: clinical findings and linkage analysis of a large pedigree. Neurology. 1987 Jun; 37(6):910-5. PMID: 3587641.
    Citations: 8     Fields:    Translation:Humans
  101. Alper CA. Inherited deficiencies of complement components in man. Immunol Lett. 1987 Feb; 14(3):175-81. PMID: 3570360.
    Citations: 3     Fields:    Translation:Humans
  102. Layrisse Z, White C, Gunczler P, Gafaro Valera L, Arias S, Yunis EJ, Alper CA, Awdeh ZL. Sharing of MHC haplotypes among apparently unrelated patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Immunogenetics. 1987; 25(2):99-103. PMID: 3493216.
    Citations: 1     Fields:    Translation:HumansCells
  103. Wescott MZ, Awdeh ZL, Yunis EJ, Alper CA. Molecular analysis distinguishes two HLA-DR3-bearing major histocompatibility complex extended haplotypes. Immunogenetics. 1987; 26(6):370-4. PMID: 2889669.
    Citations: 14     Fields:    Translation:HumansCells
  104. Granados J, Awdeh ZL, Chen JH, Giles CM, Balner H, Yunis EJ, Alper CA. There are two C4 genetic loci and a null allele in the chimpanzee. Immunogenetics. 1987; 26(6):344-50. PMID: 3666845.
    Citations: 5     Fields:    Translation:HumansAnimals
  105. Kruskall MS, Eynon EE, Awdeh Z, Alper CA, Yunis EJ. Identification of HLA-B44 subtypes associated with extended MHC haplotypes. Immunogenetics. 1987; 26(4-5):216-9. PMID: 3653939.
    Citations: 5     Fields:    Translation:HumansCells
  106. Carroll MC, Alper CA. Polymorphism and molecular genetics of human C4. Br Med Bull. 1987 Jan; 43(1):50-65. PMID: 3315101.
    Citations: 6     Fields:    Translation:HumansCells
  107. Alper CA, Fleischnick E, Awdeh Z, Katz AJ, Yunis EJ. Extended major histocompatibility complex haplotypes in patients with gluten-sensitive enteropathy. J Clin Invest. 1987 Jan; 79(1):251-6. PMID: 3793924.
    Citations: 24     Fields:    Translation:Humans
  108. Schneider PM, Carroll MC, Alper CA, Rittner C, Whitehead AS, Yunis EJ, Colten HR. Polymorphism of the human complement C4 and steroid 21-hydroxylase genes. Restriction fragment length polymorphisms revealing structural deletions, homoduplications, and size variants. J Clin Invest. 1986 Sep; 78(3):650-7. PMID: 3018042.
    Citations: 77     Fields:    Translation:HumansCells
  109. Eynon EE, Yang SY, Cronin CR, Alosco SM, Alper CA, Yunis EJ. Characterization of HLA-Bw73 by serology and one-dimensional isoelectric focusing patterns. Hum Immunol. 1986 Aug; 16(4):356-63. PMID: 2428782.
    Citations: 1     Fields:    Translation:HumansCells
  110. Reinitz E, Lawrence M, Diamond B, Keiser H, Alper C. Arthritis and antinuclear antibodies (ANA) with inherited deficiency of the sixth component of complement (C6). Ann Rheum Dis. 1986 May; 45(5):431-4. PMID: 3487293.
    Citations: 6     Fields:    Translation:Humans
  111. Alper CA, Awdeh ZL, Yunis EJ. Complotypes, extended haplotypes, male segregation distortion, and disease markers. Hum Immunol. 1986 Apr; 15(4):366-73. PMID: 3516938.
    Citations: 6     Fields:    Translation:HumansAnimals
  112. Melamed J, Alper CA, Cicardi M, Rosen FS. The metabolism of C1 inhibitor and C1q in patients with acquired C1-inhibitor deficiency. J Allergy Clin Immunol. 1986 Feb; 77(2):322-6. PMID: 3484761.
    Citations: 4     Fields:    Translation:HumansCells
  113. Alper CA. Genetics of the complement system. Ann N Y Acad Sci. 1986; 475:32-46. PMID: 3538974.
    Citations:    Fields:    Translation:Humans
  114. Alper CA, Awdeh Z, Raum D, Yunis EJ. Complement genes of the major histocompatibility complex (complotypes), extended haplotypes and disease markers. Biochem Soc Symp. 1986; 51:19-28. PMID: 3493006.
    Citations: 1     Fields:    Translation:Humans
  115. Awdeh ZL, Alper CA, Eynon E, Alosco SM, Stein R, Yunis EJ. Unrelated individuals matched for MHC extended haplotypes and HLA-identical siblings show comparable responses in mixed lymphocyte culture. Lancet. 1985 Oct 19; 2(8460):853-6. PMID: 2864576.
    Citations: 10     Fields:    Translation:Humans
  116. Eisenbarth GS, Srikanta S, Fleischnick E, Ganda OP, Jackson RA, Brink SJ, Soeldner JS, Yunis EJ, Alper C. Progressive autoimmune beta cell insufficiency: occurrence in the absence of high-risk HLA alleles DR3, DR4. Diabetes Care. 1985 Sep-Oct; 8(5):477-80. PMID: 3876922.
    Citations: 4     Fields:    Translation:Humans
  117. Rao CP, Minta JO, Laski B, Alper CA, Gelfand EW. Inherited C8 beta subunit deficiency in a patient with recurrent meningococcal infections: in vivo functional kinetic analysis of C8. Clin Exp Immunol. 1985 Apr; 60(1):183-90. PMID: 3924449.
    Citations: 2     Fields:    Translation:Humans
  118. Alper CA, Awdeh ZL, Raum DD, Yunis EJ. Possible human analogs of the murine T/t complex. Exp Clin Immunogenet. 1985; 2(2):125-36. PMID: 3917226.
    Citations: 3     Fields:    Translation:HumansAnimals
  119. Yunis EJ, Awdeh Z, Johnson A, Suciu-Foca N, Robinson MA, Hartzman R, Raum D, Fleischnick E, Alper CA. Complotype genetic loci segregate more frequently with HLA-DR than with HLA-B. Immunogenetics. 1985; 21(1):25-31. PMID: 3871424.
    Citations: 3     Fields:    Translation:Humans
  120. Alper CA, Fleischnick E, Awdeh Z, Raum D, Crigler JF, Gerald PS, Yunis EJ. Extended MHC haplotypes in salt-losing 21-hydroxylase deficiency. Ann N Y Acad Sci. 1985; 458:28-35. PMID: 3879127.
    Citations: 1     Fields:    Translation:Humans
  121. Muir WA, Hedrick S, Alper CA, Ratnoff OD, Schacter B, Wisnieski JJ. Inherited incomplete deficiency of the fourth component of complement (C4) determined by a gene not linked to human histocompatibility leukocyte antigens. J Clin Invest. 1984 Oct; 74(4):1509-14. PMID: 6480834.
    Citations: 6     Fields:    Translation:Humans
  122. Raum D, Awdeh Z, Yunis EJ, Alper CA, Gabbay KH. Extended major histocompatibility complex haplotypes in type I diabetes mellitus. J Clin Invest. 1984 Aug; 74(2):449-54. PMID: 6746903.
    Citations: 48     Fields:    Translation:Humans
  123. Srikanta S, Ganda OP, Jackson RA, Brink SJ, Fleischnick E, Yunis E, Alper C, Soeldner JS, Eisenbarth GS. Pre-type 1 (insulin-dependent) diabetes: common endocrinological course despite immunological and immunogenetic heterogeneity. Diabetologia. 1984 Jul; 27 Suppl:146-8. PMID: 6383919.
    Citations: 10     Fields:    Translation:Humans
  124. Granados J, Cramer DV, Caputo JB, Marcus D, Alper CA. Genetic polymorphism of the sixth component (C6) of rat complement. J Immunol. 1984 Jul; 133(1):405-7. PMID: 6586834.
    Citations: 3     Fields:    Translation:Animals
  125. Raum D, Surgenor T, Awdeh Z, Marcus D, Blumenthal M, Yunis EJ, Alper CA. An unusual "morphologic" variant of BF S. Am J Hum Genet. 1984 Mar; 36(2):346-51. PMID: 6585138.
    Citations: 2     Fields:    Translation:HumansCells
  126. Whitehead AS, Woods DE, Fleischnick E, Chin JE, Yunis EJ, Katz AJ, Gerald PS, Alper CA, Colten HR. DNA polymorphism of the C4 genes. A new marker for analysis of the major histocompatibility complex. N Engl J Med. 1984 Jan 12; 310(2):88-91. PMID: 6581384.
    Citations: 27     Fields:    Translation:HumansCells
  127. Alper CA, Rosen FS. Inherited deficiencies of complement proteins in man. Springer Semin Immunopathol. 1984; 7(2-3):251-61. PMID: 6238435.
    Citations: 5     Fields:    Translation:HumansAnimals
  128. Raum DD, Awdeh ZL, Page PL, Yunis EJ, Alper CA. MHC determinants of response to Rh immunization. J Immunol. 1984 Jan; 132(1):157-9. PMID: 6197442.
    Citations: 1     Fields:    Translation:Humans
  129. Raum D, Awdeh Z, Anderson J, Strong L, Granados J, Teran L, Giblett E, Yunis EJ, Alper CA. Human C4 haplotypes with duplicated C4A or C4B. Am J Hum Genet. 1984 Jan; 36(1):72-9. PMID: 6607672.
    Citations: 21     Fields:    Translation:HumansCells
  130. Matsui Y, Alosco SM, Awdeh Z, Duquesnoy RJ, Page PL, Hartzman RJ, Alper CA, Yunis EJ. Linkage disequilibrium of HLA-SB1 with the HLA-A1, B8, DR3, SCO1 and of HLA-SB4 with the HLA-A26, Bw38, Dw10, DR4, SC21 extended haplotypes. Immunogenetics. 1984; 20(6):623-31. PMID: 6239824.
    Citations: 7     Fields:    Translation:Humans
  131. Dias da Silva W, Calich VL, Kipnis TL, Rosen FS, Alper CA. Complement in the serum and venom of Brazilian snakes (Crotalidae). Acta Pathol Microbiol Immunol Scand Suppl. 1984; 284:97-103. PMID: 6587747.
    Citations: 1     Fields:    Translation:HumansAnimals
  132. Alper CA, Marcus D, Raum D, Petersen BH, Spira TJ. Genetic polymorphism in C8 beta-chains. Evidence for two unlinked genetic loci for the eighth component of human complement (C8). J Clin Invest. 1983 Nov; 72(5):1526-31. PMID: 6415112.
    Citations: 13     Fields:    Translation:Humans
  133. Yunis EJ, Awdeh Z, Raum D, Alper CA. The MHC in human bone marrow allotransplantation. Clin Haematol. 1983 Oct; 12(3):641-80. PMID: 6227438.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  134. Mauff G, Alper CA, Awdeh Z, Batchelor JR, Bertrams J, Bruun-Petersen G, Dawkins RL, Démant P, Edwards J, Grosse-Wilde H, Hauptmann G, Klouda P, Lamm L, Mollenhauer E, Nerl C, Olaisen B, O'Neill G, Rittner C, Roos MH, Skanes V, Teisberg P, Wells L. Statement on the nomenclature of human C4 allotypes. Immunobiology. 1983 Mar; 164(2):184-91. PMID: 6852863.
    Citations: 83     Fields:    Translation:Humans
  135. Fleischnick E, Awdeh ZL, Raum D, Granados J, Alosco SM, Crigler JF, Gerald PS, Giles CM, Yunis EJ, Alper CA. Extended MHC haplotypes in 21-hydroxylase-deficiency congenital adrenal hyperplasia: shared genotypes in unrelated patients. Lancet. 1983 Jan 22; 1(8317):152-6. PMID: 6130199.
    Citations: 18     Fields:    Translation:HumansCells
  136. Awdeh ZL, Raum D, Yunis EJ, Alper CA. Extended HLA/complement allele haplotypes: evidence for T/t-like complex in man. Proc Natl Acad Sci U S A. 1983 Jan; 80(1):259-63. PMID: 6401863.
    Citations: 98     Fields:    Translation:Humans
  137. Alper CA, Raum D, Karp S, Awdeh ZL, Yunis EJ. Serum complement 'supergenes' of the major histocompatibility complex in man (complotypes). Vox Sang. 1983; 45(1):62-7. PMID: 6554026.
    Citations: 41     Fields:    Translation:Humans
  138. Alper CA, Awdeh ZL, Raum DD, Yunis EJ. Extended major histocompatibility complex haplotypes in man: role of alleles analogous to murine t mutants. Clin Immunol Immunopathol. 1982 Aug; 24(2):276-85. PMID: 6811180.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  139. Chao FC, Tullis JL, Alper CA, Glynn RJ, Silbert JE. Alteration in plasma proteins and platelet functions with aging and cigarette smoking in healthy men. Thromb Haemost. 1982 Jun 28; 47(3):259-64. PMID: 6981228.
    Citations: 6     Fields:    Translation:Humans
  140. Ballow M, McLean RH, Yunis EJ, Awdeh ZL, O'Neill GJ, Einarson M, Alper CA. C4 polymorphism and HLA linkage: studies in a family with hereditary C4 deficiency. Clin Immunol Immunopathol. 1981 Sep; 20(3):354-60. PMID: 7341033.
    Citations: 1     Fields:    Translation:Humans
  141. Arnaout MA, Luscinskas FW, Lionetti FJ, Alper CA, Valeri CR. Alternative complement pathway-dependent ingestion of fluolite particles by human granulocytes. J Immunol. 1981 Jul; 127(1):278-81. PMID: 6787126.
    Citations:    Fields:    Translation:HumansCells
  142. Mann J, O'Brien R, Hostetter MK, Alper CA, Rosen FS, Babior BM. The third component of complement: covalent attachment of a radioactive sugar to the labile binding site of C3 via the alternative pathway. J Immunol. 1981 Jun; 126(6):2370-2. PMID: 6785350.
    Citations: 6     Fields:    Translation:HumansCells
  143. Colten HR, Alper CA, Rosen FS. Genetics and biosynthesis of complement proteins. N Engl J Med. 1981 Mar 12; 304(11):653-6. PMID: 6450325.
    Citations: 3     Fields:    Translation:HumansAnimals
  144. Raum DD, Awdeh ZL, Glass D, Yunis E, Alper CA. The location of C2, C4, and BF relative to HLA-B and HLA-D. Immunogenetics. 1981 Mar 01; 12(5-6):473-83. PMID: 7216322.
    Citations: 13     Fields:    Translation:Humans
  145. Awdeh ZL, Raum DD, Glass D, Agnello V, Schur PH, Johnston RB, Gelfand EW, Ballow M, Yunis E, Alper CA. Complement-human histocompatibility antigen haplotypes in C2 deficiency. J Clin Invest. 1981 Feb; 67(2):581-3. PMID: 7462431.
    Citations: 5     Fields:    Translation:Humans
  146. Raum D, Awdeh Z, Alper CA. BF types and the mode of inheritance of insulin-dependent diabetes mellitus (IDDM). Immunogenetics. 1981; 12(1-2):59-74. PMID: 7009418.
    Citations: 12     Fields:    Translation:Humans
  147. Awdeh ZL, Ochs HD, Alper CA. Genetic analysis of C4 deficiency. J Clin Invest. 1981 Jan; 67(1):260-3. PMID: 7451653.
    Citations: 11     Fields:    Translation:Humans
  148. Raum D, Marcus D, Alper CA. Genetic polymorphism of human plasminogen. Am J Hum Genet. 1980 Sep; 32(5):681-9. PMID: 7424908.
    Citations: 15     Fields:    Translation:Humans
  149. Awdeh ZL, Alper CA. Inherited structural polymorphism of the fourth component of human complement. Proc Natl Acad Sci U S A. 1980 Jun; 77(6):3576-80. PMID: 6932037.
    Citations: 154     Fields:    Translation:Humans
  150. Raum D, Marcus D, Alper CA, Levey R, Taylor PD, Starzl TE. Synthesis of human plasminogen by the liver. Science. 1980 May 30; 208(4447):1036-7. PMID: 6990488.
    Citations: 18     Fields:    Translation:Humans
  151. Alper CA, Raum D, Awdeh ZL, Petersen BH, Taylor PD, Starzl TE. Studies of hepatic synthesis in vivo of plasma proteins, including orosomucoid, transferrin, alpha 1-antitrypsin, C8, and factor B. Clin Immunol Immunopathol. 1980 May; 16(1):84-9. PMID: 6769626.
    Citations: 31     Fields:    Translation:HumansAnimals
  152. Awdeh ZL, Alper CA. Inherited polymorphism of human C4 as revealed by desialyzation. Immunobiology. 1980; 158(1-2):35-41. PMID: 7203518.
    Citations: 8     Fields:    Translation:Humans
  153. Shows TB, Alper CA, Bootsma D, Dorf M, Douglas T, Huisman T, Kit S, Klinger HP, Kozak C, Lalley PA, Lindsley D, McAlpine PJ, McDougall JK, Meera Khan P, Meisler M, Morton NE, Opitz JM, Partridge CW, Payne R, Roderick TH, Rubinstein P, Ruddle FH, Shaw M, Spranger JW, Weiss K. International System for Human Gene Nomenclature (1979) ISGN (1979). Birth Defects Orig Artic Ser. 1980; 15(11):96-116. PMID: 7213958.
    Citations: 2     Fields:    Translation:Humans
  154. Raum D, Donaldson VH, Rosen FS, Alper CA. Genetics of complement. Curr Top Hematol. 1980; 3:111-74. PMID: 7035077.
    Citations: 3     Fields:    Translation:Humans
  155. Mauff G, Alper CA, Hobart M, Kühnl P, Kunstmann G, Meo T, Olving JH, Rittner C. Statement on the nomenclature of human C6 polymorphism. Immunobiology. 1980; 158(1-2):139-43. PMID: 7203515.
    Citations: 5     Fields:    Translation:Humans
  156. Raum D, Balner H, Petersen BH, Alper CA. Genetic polymorphism of serum complement components in the chimpanzee. Immunogenetics. 1980; 10(5):455-68. PMID: 22457919.
    Citations: 5     Fields:    Translation:HumansAnimals
  157. Awdeh ZL, Raum D, Alper CA. Genetic polymorphism of human complement C4 and detection of heterozygotes. Nature. 1979 Nov 08; 282(5735):205-7. PMID: 492334.
    Citations: 42     Fields:    Translation:Humans
  158. Raum D, Spence MA, Balavitch D, Tideman S, Merritt AD, Taggart RT, Petersen BH, Day NK, Alper CA. Genetic control of the eighth component of complement. J Clin Invest. 1979 Sep; 64(3):858-65. PMID: 468996.
    Citations: 20     Fields:    Translation:Humans
  159. Raum D, Alper CA, Stein R, Gabbay KH. Genetic marker for insulin-dependent diabetes mellitus. Lancet. 1979 Jun 09; 1(8128):1208-10. PMID: 87677.
    Citations: 27     Fields:    Translation:HumansCells
  160. Raum D, Glass D, Carpenter CB, Schur PH, Alper CA. Mapping of the structural gene for the second component of complement with respect to the human major histocompatibility complex. Am J Hum Genet. 1979 Jan; 31(1):35-41. PMID: 312013.
    Citations: 15     Fields:    Translation:Humans
  161. Shows TB, Alper CA, Bootsma D, Dorf M, Douglas T, Huisman T, Kit S, Klinger HP, Kozak C, Lalley PA, Lindsley D, McAlpine PJ, McDougall JK, Meera Khan P, Meisler M, Morton NE, Opitz JM, Partridge CW, Payne R, Roderick TH, Rubinstein P, Ruddle FH, Shaw M, Spranger JW, Weiss K. International system for human gene nomenclature (1979) ISGN (1979). Cytogenet Cell Genet. 1979; 25(1-4):96-116. PMID: 295268.
    Citations: 52     Fields:    Translation:HumansCells
  162. Raum D, Glass D, Agnello V, Schur P, Alper CA. Congenital deficiency of C2 and factor B. N Engl J Med. 1978 Dec 07; 299(23):1313. PMID: 714103.
    Citations: 2     Fields:    Translation:Humans
  163. Pariser KM, Raum D, Berkman EM, Alper CA, Agnello V. Evidence for a silent or null gene in hereditary C2 deficiency. J Immunol. 1978 Dec; 121(6):2580-1. PMID: 722085.
    Citations: 10     Fields:    Translation:Humans
  164. Davis AE, Gelfand EW, Schur PH, Rosen FS, Alper CA. IgG subclass studies of C3 nephritic factor. Clin Immunol Immunopathol. 1978 Sep; 11(1):98-101. PMID: 699392.
    Citations:    Fields:    Translation:HumansCells
  165. Voelkel EF, Levine L, Alper CA, Tashjian AH. Acute phase reactants ceruloplasmin and haptoglobin and their relationship to plasma prostaglandins in rabbits bearing the VS2 carcinoma. J Exp Med. 1978 Apr 01; 147(4):1078-88. PMID: 650152.
    Citations: 4     Fields:    Translation:Animals
  166. Glass D, Raum D, Balavitch D, Kagan E, Rabson A, Schur PH, Alper CA. Inherited deficiency of the sixth component of complement: a silent or null gene. J Immunol. 1978 Feb; 120(2):538-41. PMID: 621392.
    Citations: 10     Fields:    Translation:Humans
  167. Davis AE, Davis JS, Rabson AR, Osofsky SG, Colten HR, Rosen FS, Alper CA. Homozygous C3 deficiency: detection of C3 by radioimmunoassay. Clin Immunol Immunopathol. 1977 Nov; 8(3):543-50. PMID: 303161.
    Citations: 10     Fields:    Translation:HumansCells
  168. Arnaout MA, Davis AE, Rosen RS, Alper CA. Complement activation in semisolid media: insolubilization of alternative pathway convertases in agar gels with C3 nephritic factor-containing sera. J Immunol. 1977 Oct; 119(4):1316-20. PMID: 894039.
    Citations: 2     Fields:    Translation:Humans
  169. Davis AE, Arnaout MA, Alper CA, Rosen FS. Transfer of C3 nephritic factor from mother to fetus. Is C3 nephritic factor IgG? N Engl J Med. 1977 Jul 21; 297(3):144-5. PMID: 865586.
    Citations: 6     Fields:    Translation:Humans
  170. Hall JE, Alper CA. Genetic polymorphism of the sixth component of complement (C6) in the rhesus monkey. J Immunol. 1977 Jul; 119(1):253-5. PMID: 406324.
    Citations: 4     Fields:    Translation:Animals
  171. Ochs HD, Rosenfeld SI, Thomas ED, Giblett ER, Alper CA, Dupont B, Schaller JG, Gilliland BC, Hansen JA, Wedgwood RJ. Linkage between the gene (or genes) controlling synthesis of the fourth component of complement and the major histocompatibility complex. N Engl J Med. 1977 Mar 03; 296(9):470-5. PMID: 138091.
    Citations: 22     Fields:    Translation:HumansCells
  172. Alper CA, Davis AE, Rosen FS. Complement and immunologic disease. Arthritis Rheum. 1977 Mar; 20(2 Suppl):449-58. PMID: 263919.
    Citations: 1     Fields:    Translation:Humans
  173. Raum D, Glass D, Carpenter CB, Alper CA, Schur PH. The chromosomal order of genes controlling the major histocompatibility complex, properdin factor B, and deficiency of the second component of complement. J Clin Invest. 1976 Nov; 58(5):1240-8. PMID: 993342.
    Citations: 15     Fields:    Translation:Humans
  174. Alper CA. Inherited structural polymorphism in human C2: evidence for genetic linkage between C2 and Bf. J Exp Med. 1976 Oct 01; 144(4):1111-5. PMID: 978135.
    Citations: 79     Fields:    Translation:Humans
  175. Alper CA, Balavitch D. Cobra venom factor: evidence for its being altered cobra C3 (the third component of complement). Science. 1976 Mar 26; 191(4233):1275-6. PMID: 56780.
    Citations: 25     Fields:    Translation:Animals
  176. Ziegler JB, Watson L, Goodkofsky I, Alper CA, Lepow IH. Complement activation in semi-solid medium: Insolubilization of properdin and the third component of complement (C3) in agar gels. J Immunol. 1976 Jan; 116(1):75-9. PMID: 812917.
    Citations:    Fields:    Translation:HumansCells
  177. Alper CA, Colten HR, Gear JS, Rabson AR, Rosen FS. Homozygous human C3 deficiency. The role of C3 in antibody production, C-1s-induced vasopermeability, and cobra venom-induced passive hemolysis. J Clin Invest. 1976 Jan; 57(1):222-9. PMID: 1107355.
    Citations: 17     Fields:    Translation:HumansCells
  178. Bhan AK, Grand RJ, Colten HR, Alper CA. Liver in alpha1-antitrypsin deficiency: morphologic observations and in vitro synthesis of alpha1-antitrypsin. Pediatr Res. 1976 Jan; 10(1):35-40. PMID: 1082120.
    Citations: 7     Fields:    Translation:Humans
  179. Alper CA, Rosen FS. Genetics of the complement system. Adv Hum Genet. 1976; 7:141-88. PMID: 827931.
    Citations: 16     Fields:    Translation:HumansAnimals
  180. Ziegler JB, Watson L, Alper CA. Genetic polymorphism of properdin factor B in the rhesus: evidence for single subunit structure in primates. J Immunol. 1975 Jun; 114(6):1649-53. PMID: 1127225.
    Citations: 3     Fields:    Translation:AnimalsCells
  181. Stossel TP, Field RJ, Gitlin JD, Alper CA, Rosen FS. The opsonic fragment of the third component of human complement (C3). J Exp Med. 1975 Jun 01; 141(6):1329-47. PMID: 236357.
    Citations: 34     Fields:    Translation:HumansCells
  182. Einstein LP, Alper CA, Bloch KJ, Herrin JT, Rosen FS, David JR, Colten HR. Biosynthetic defect in monocytes from human beings with genetic deficiency of the second component of complement. N Engl J Med. 1975 May 29; 292(22):1169-71. PMID: 1124106.
    Citations: 11     Fields:    Translation:HumansCells
  183. Ziegler JB, Alper CA, Balner H. Properdin factor B and histocompatibility loci linked in the rhesus monkey. Nature. 1975 Apr 17; 254(5501):609-11. PMID: 48198.
    Citations: 19     Fields:    Translation:Animals
  184. Alper CA, Rosen FS. Clinical applications of complement assays. Adv Intern Med. 1975; 20:61-88. PMID: 46689.
    Citations: 2     Fields:    Translation:HumansCells
  185. Zucker MB, Grant RA, Alper CA, Goodkofsky I, Lepow IH. Requirement for complement components and fibrinogen in the zymosan-induced release reaction of human blood platelets. J Immunol. 1974 Dec; 113(6):1744-51. PMID: 4610046.
    Citations: 7     Fields:    Translation:HumansCells
  186. Schur PH, Alpert E, Alper C. Gamma G subgroups in human fetal, cord, and maternal sera. Clin Immunol Immunopathol. 1973 Nov; 2(1):62-6. PMID: 4129991.
    Citations: 6     Fields:    Translation:Humans
  187. Alper CA, Bloch KJ, Rosen FS. Increased susceptibility to infection in a patient with type II essential hypercatabolism of C3. N Engl J Med. 1973 Mar 22; 288(12):601-6. PMID: 4686987.
    Citations: 32     Fields:    Translation:Humans
  188. Stossel TP, Alper CA, Rosen FS. Serum-dependent phagocytosis of paraffin oil emulsified with bacterial lipopolysaccharide. J Exp Med. 1973 Mar 01; 137(3):690-705. PMID: 4631990.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  189. Alper CA, Goodkofsky I, Lepow IH. The relationship of glycine-rich -glycoprotein to factor B in the properdin system and to the cobra factor-binding protein of huan serum. J Exp Med. 1973 Feb 01; 137(2):424-37. PMID: 4734403.
    Citations: 14     Fields:    Translation:HumansAnimals