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profileHomayoun Kazemi, M.D.

TitleProfessor of Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Bulfinch 148 - Pulmonary
55 Fruit St
Boston MA 02114
Phone617/724-7821
Fax617/726-6878
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Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01HL029620     (KAZEMI, HOMAYOUN)Jan 1, 1983 - Dec 31, 1988
NIH/NHLBI
REGULATION OF (C1) AND CNS ACID-BASE BALANCE
Role: Principal Investigator

R01HL029493     (KAZEMI, HOMAYOUN)Sep 1, 1982 - Aug 31, 1988
NIH/NHLBI
CENTRAL REGULATION OF RESPIRATION METABOLIC FACTORS
Role: Principal Investigator

T32HL007354     (KAZEMI, HOMAYOUN)Jul 1, 1978 - Jun 30, 1993
NIH/NHLBI
PULMONARY PATHOPHYSIOLOGY
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Kazemi H. Midbrain neurotransmitters in acute hypoxic ventilatory response. Adv Exp Med Biol. 2006; 580:223-6; discussion 351-9. PMID: 16683723.
    View in: PubMed
  2. Kazemi H. CO2/H+ signal transduction and central ventilatory control. Adv Exp Med Biol. 2003; 536:401-6. PMID: 14635693.
    View in: PubMed
  3. Kazemi H, Systrom D. Carbon dioxide pressure-concentration relationship in arterial and mixed venous blood. J Appl Physiol (1985). 2001 Nov; 91(5):2413; author reply 2413-4. PMID: 11706821.
    View in: PubMed
  4. Dwinell MR, Kazemi H, Lam JT, Powell FL. Central amino acid neurotransmitters, ventilatory output and metabolism during acute hypoxia in anesthetized rats. Adv Exp Med Biol. 2001; 499:291-6. PMID: 11729894.
    View in: PubMed
  5. Systrom DM, Hrovat M, Oelberg D, Kazemi H. Skeletal muscle chemoreflex in exercise ventilatory control. Adv Exp Med Biol. 2001; 499:343-8. PMID: 11729905.
    View in: PubMed
  6. Burton MD, Kazemi H. Neurotransmitters in central respiratory control. Respir Physiol. 2000 Sep; 122(2-3):111-21. PMID: 10967338.
    View in: PubMed
  7. Hoop B, Beagle JL, Maher TJ, Kazemi H. Brainstem amino acid neurotransmitters and hypoxic ventilatory response. Respir Physiol. 1999 Dec 01; 118(2-3):117-29. PMID: 10647857.
    View in: PubMed
  8. Krause WL, Kazemi H, Burton MD. Potential role for imidazole in the rhythmic respiratory activity of the in vitro neonatal rat brainstem. Neurosci Lett. 1998 Jul 31; 251(3):153-6. PMID: 9726366.
    View in: PubMed
  9. Evans AB, Tsai LW, Oelberg DA, Kazemi H, Systrom DM. Skeletal muscle ECF pH error signal for exercise ventilatory control. J Appl Physiol (1985). 1998 Jan; 84(1):90-6. PMID: 9451622.
    View in: PubMed
  10. Beagle JL, Hoop B, Kazemi H. Phrenic nerve response to glutamate antagonist microinjection in the ventral medulla. Adv Exp Med Biol. 1998; 450:61-5. PMID: 10026964.
    View in: PubMed
  11. Hoop B, Krause WL, Kazemi H. Temporal correlation in phrenic neural activity. Adv Exp Med Biol. 1998; 450:111-8. PMID: 10026971.
    View in: PubMed
  12. Burton MD, Kawashima A, Brayer JA, Kazemi H, Shannon DC, Schuchardt A, Costantini F, Pachnis V, Kinane TB. RET proto-oncogene is important for the development of respiratory CO2 sensitivity. J Auton Nerv Syst. 1997 Apr 14; 63(3):137-43. PMID: 9138245.
    View in: PubMed
  13. Burton MD, Johnson DC, Kazemi H. The central respiratory effects of acetylcholine vary with CSF pH. J Auton Nerv Syst. 1997 Jan 12; 62(1-2):27-32. PMID: 9021646.
    View in: PubMed
  14. Kazemi H, Beagle J, Maher T, Hoop B. Afferent input from peripheral chemoreceptors in response to hypoxia and amino acid neurotransmitter generation in the medulla. Adv Exp Med Biol. 1996; 410:365-9. PMID: 9030326.
    View in: PubMed
  15. Hoop B, Burton MD, Kazemi H, Liebovitch LS. Correlation in stimulated respiratory neural noise. Chaos. 1995 Sep; 5(3):609-612. PMID: 12780216.
    View in: PubMed
  16. Soto-Arape I, Burton MD, Kazemi H. Central amino acid neurotransmitters and the hypoxic ventilatory response. Am J Respir Crit Care Med. 1995 Apr; 151(4):1113-20. PMID: 7697240.
    View in: PubMed
  17. Burton MD, Nouri M, Kazemi H. Acetylcholine and central respiratory control: perturbations of acetylcholine synthesis in the isolated brainstem of the neonatal rat. Brain Res. 1995 Jan 23; 670(1):39-47. PMID: 7719722.
    View in: PubMed
  18. Kazemi H, Burton MD. Role of acetylcholine as an essential neurotransmitter in central respiratory drive. Adv Exp Med Biol. 1995; 393:29-32. PMID: 8629499.
    View in: PubMed
  19. Johnson DC, Kazemi H. Central control of ventilation in neuromuscular disease. Clin Chest Med. 1994 Dec; 15(4):607-17. PMID: 7867278.
    View in: PubMed
  20. Burton MD, Nouri K, Baichoo S, Samuels-Toyloy N, Kazemi H. Ventilatory output and acetylcholine: perturbations in release and muscarinic receptor activation. J Appl Physiol (1985). 1994 Nov; 77(5):2275-84. PMID: 7868445.
    View in: PubMed
  21. Kazemi H, Soto-Arape I. Central glutamate and substance-P in the hypoxic ventilatory response. Adv Exp Med Biol. 1994; 360:281-4. PMID: 7532903.
    View in: PubMed
  22. Hoop B, Kazemi H, Liebovitch L. Rescaled range analysis of resting respiration. Chaos. 1993 Jan; 3(1):27-29. PMID: 12780012.
    View in: PubMed
  23. Ang RC, Hoop B, Kazemi H. Brain glutamate metabolism during metabolic alkalosis and acidosis. J Appl Physiol (1985). 1992 Dec; 73(6):2552-8. PMID: 1362726.
    View in: PubMed
  24. Ang RC, Hoop B, Kazemi H. Role of glutamate as the central neurotransmitter in the hypoxic ventilatory response. J Appl Physiol (1985). 1992 Apr; 72(4):1480-7. PMID: 1350580.
    View in: PubMed
  25. Fleming H, Burton M, Johnson DC, Kazemi H. Sodium salicylate centrally augments ventilation through cholinergic mechanisms. J Appl Physiol (1985). 1991 Dec; 71(6):2299-303. PMID: 1778926.
    View in: PubMed
  26. Systrom DM, Fragoso CV, Kanarek DJ, Kazemi H. Ammonium ion and the anaerobic threshold in man. Chest. 1991 May; 99(5):1197-202. PMID: 2019178.
    View in: PubMed
  27. Kazemi H, Hoop B. Glutamic acid and gamma-aminobutyric acid neurotransmitters in central control of breathing. J Appl Physiol (1985). 1991 Jan; 70(1):1-7. PMID: 1672687.
    View in: PubMed
  28. Hoop B, Masjedi MR, Shih VE, Kazemi H. Brain glutamate metabolism during hypoxia and peripheral chemodenervation. J Appl Physiol (1985). 1990 Jul; 69(1):147-54. PMID: 1975573.
    View in: PubMed
  29. Burton MD, Johnson DC, Kazemi H. Adrenergic and cholinergic interaction in central ventilatory control. J Appl Physiol (1985). 1990 May; 68(5):2092-9. PMID: 2163380.
    View in: PubMed
  30. Systrom DM, Kanarek DJ, Kohler SJ, Kazemi H. 31P nuclear magnetic resonance spectroscopy study of the anaerobic threshold in humans. J Appl Physiol (1985). 1990 May; 68(5):2060-6. PMID: 2361908.
    View in: PubMed
  31. Masjedi MR, Kazemi H, Johnson DC. Effects of passive smoking on the pulmonary function of adults. Thorax. 1990 Jan; 45(1):27-31. PMID: 2321173; PMCID: PMC475636.
  32. Johnson DC, Nishimura M, Okunieff P, Kazemi H, Hitzig B. Effects of hypothermia on rat brain pHi and phosphate metabolite regulation by 31P-NMR. J Appl Physiol (1985). 1989 Dec; 67(6):2527-34. PMID: 2606861.
    View in: PubMed
  33. Burton MD, Johnson DC, Kazemi H. CSF acidosis augments ventilation through cholinergic mechanisms. J Appl Physiol (1985). 1989 Jun; 66(6):2565-72. PMID: 2501287.
    View in: PubMed
  34. Nishimura M, Johnson DC, Hitzig BM, Okunieff P, Kazemi H. Effects of hypercapnia on brain pHi and phosphate metabolite regulation by 31P-NMR. J Appl Physiol (1985). 1989 May; 66(5):2181-8. PMID: 2501277.
    View in: PubMed
  35. Shepherd KE, Oliver LC, Kazemi H. Diffuse malignant pleural mesothelioma in an urban hospital: clinical spectrum and trend in incidence over time. Am J Ind Med. 1989; 16(4):373-83. PMID: 2610210.
    View in: PubMed
  36. Blumenstock DA, Systrom D, Hales C, Alpern H, Kazemi H. Pulmonary function of haplotype-matched and mismatched allografts in dogs treated with total-body irradiation, autologous marrow transplantation, methotrexate, and donor blood. Transplantation. 1988 Oct; 46(4):496-501. PMID: 3051555.
    View in: PubMed
  37. Hoop B, Systrom DM, Shih VE, Kazemi H. Central respiratory effects of glutamine synthesis inhibition in dogs. J Appl Physiol (1985). 1988 Sep; 65(3):1099-109. PMID: 2903134.
    View in: PubMed
  38. Nishimura M, Johnson DC, Kazemi H. Effects of inhibitors on chloride outflux from cerebrospinal fluid. J Appl Physiol (1985). 1988 May; 64(5):2183-9. PMID: 3391916.
    View in: PubMed
  39. Hassoun PM, Shepherd KE, Flotte TJ, Kazemi H. Erythema induratum and active pulmonary tuberculosis. Am J Med. 1988 Apr; 84(4):784-5. PMID: 3400668.
    View in: PubMed
  40. Kriebel D, Brain JD, Sprince NL, Kazemi H. The pulmonary toxicity of beryllium. Am Rev Respir Dis. 1988 Feb; 137(2):464-73. PMID: 3277503.
    View in: PubMed
  41. Choi NC, Kanarek DJ, Kazemi H. Prospective study of pulmonary tolerance to radiotherapy or radiotherapy plus multidrug chemotherapy for loco-regional lung carcinoma. Antibiot Chemother (1971). 1988; 41:213-9. PMID: 3245690.
    View in: PubMed
  42. Johnson DC, Singer S, Hoop B, Kazemi H. Chloride flux from blood to CSF: inhibition by furosemide and bumetanide. J Appl Physiol (1985). 1987 Oct; 63(4):1591-600. PMID: 3693196.
    View in: PubMed
  43. Kneussl M, Hitzig B, Hoop B, Pappagianopoulos P, Shih V, Kazemi H. [A model of the central control of respiration]. Wien Klin Wochenschr. 1986 Sep 12; 98(17):561-4. PMID: 3765644.
    View in: PubMed
  44. Sprince NL, Chamberlin RI, Hales CA, Weber AL, Kazemi H. Respiratory disease in tungsten carbide production workers. Chest. 1984 Oct; 86(4):549-57. PMID: 6434250.
    View in: PubMed
  45. Braslow NM, Hales CA, Hoop B, Kanarek DJ, Kazemi H. Noninvasive cardiac output determination using inhaled oxygen-15-labeled carbon dioxide. J Appl Physiol Respir Environ Exerc Physiol. 1982 Nov; 53(5):1125-32. PMID: 6816766.
    View in: PubMed
  46. Ginns LC, Goldenheim PD, Burton RC, Colvin RB, Miller LG, Goldstein G, Hurwitz C, Kazemi H. T-lymphocyte subsets in peripheral blood and lung lavage in idiopathic pulmonary fibrosis and sarcoidosis: analysis by monoclonal antibodies and flow cytometry. Clin Immunol Immunopathol. 1982 Oct; 25(1):11-20. PMID: 6983939.
    View in: PubMed
  47. Ginns LC, Goldenheim PD, Miller LG, Burton RC, Gillick L, Colvin RB, Goldstein G, Kung PC, Hurwitz C, Kazemi H. T-lymphocyte subsets in smoking and lung cancer: Analysis of monoclonal antibodies and flow cytometry. Am Rev Respir Dis. 1982 Aug; 126(2):265-9. PMID: 6980611.
    View in: PubMed
  48. Ahluwalia BD, Brownell GL, Hales CA, Kazemi H. An index of pulmonary edema measured with emission computed tomography. J Comput Assist Tomogr. 1981 Oct; 5(5):690-4. PMID: 6975288.
    View in: PubMed
  49. Ahluwalia B, Brownell GL, Hales C, Kazemi H. Regional lung function evaluation with nitrogen-13. Eur J Nucl Med. 1981; 6(10):453-7. PMID: 7285981.
    View in: PubMed
  50. Hales CA, Kanarek DJ, Ahluwalia B, Latty A, Erdmann J, Javaheri S, Kazemi H. Regional edema formation in isolated perfused dog lungs. Circ Res. 1981 Jan; 48(1):121-7. PMID: 7438342.
    View in: PubMed
  51. Blumenstock DA, Cannon FD, Hales CA, Vlahovic VL, Alpern H, Kazemi H. Pulmonary function of DLA-nonidentical lung allografts in dogs treated with lethal total-body irradiation, autologous bone marrow transplantation, and methotrexate. Transplantation. 1979 Sep; 28(3):223-7. PMID: 386585.
    View in: PubMed
  52. Javaheri S, Nardell EA, Kazemi H. Role of PCO2 as determinant of CSF [HCO-3] in metabolic acidosis. Respir Physiol. 1979 Feb; 36(2):155-66. PMID: 441571.
    View in: PubMed
  53. Kazemi H, Hales C, Ahluwalia B. N13-N2(1). Prog Nucl Med. 1978; 5:93-114. PMID: 748977.
    View in: PubMed
  54. Hales CA, Rouse ET, Kazemi H. Failure of saralasin acetate, a competitive inhibitor of angiotensin II, to diminish alveolar hypoxic vasoconstriction in the dog. Cardiovasc Res. 1977 Nov; 11(6):541-6. PMID: 603879.
    View in: PubMed
  55. Hales CA, Kazemi H. Clinical significance of pulmonary function tests. Pulmonary function after uncomplicated myocardial infarction. Chest. 1977 Sep; 72(3):350-8. PMID: 891288.
    View in: PubMed
  56. Blumenstock DA, Cannon FD, Franck WA, Hales CA, Kazemi H, Ferrebee JW. Allotransplantation of the lung without immunosuppression after transplantation. II. Combined autotransplantation of bone marrow and allotransplantation of lung. Transplantation. 1977 Sep; 24(3):194-200. PMID: 339431.
    View in: PubMed
  57. Hales CA, Rouse E, Buchwald IA, Kazemi H. Role of prostaglandins in alveolar hypoxic vasoconstriction. Respir Physiol. 1977 Apr; 29(2):151-62. PMID: 866810.
    View in: PubMed
  58. Hales CA, Gibbons R, Burnham C, Kazemi H. Determinants of regional distribution of a bolus inhaled from residual volume. J Appl Physiol. 1976 Sep; 41(3):400-8. PMID: 965310.
    View in: PubMed
  59. Hales CA, Ahluwalia B, Kazemi H. Strength of pulmonary vascular response to regional alveolar hypoxia. J Appl Physiol. 1975 Jun; 38(6):1083-7. PMID: 1141122.
    View in: PubMed
  60. Hales CA, Kazemi H. Role of histamine in the hypoxic vascular response of the lung. Respir Physiol. 1975 Jun; 24(1):81-8. PMID: 1197948.
    View in: PubMed
  61. Blumenstock DA, Kazemi H, Hales CA, Cannon FD, Zumwalt R, Ferrebee J. Allotransplantation of lung without immunosuppression after transplantation. I. Staged transplantation of bone marrow and lung. Transplantation. 1974 Oct; 18(4):336-42. PMID: 4609256.
    View in: PubMed
  62. Hales CA, Kazemi H. Hypoxic vascular response of the lung: effect of aminophylline and epinephrine. Am Rev Respir Dis. 1974 Aug; 110(2):126-32. PMID: 4413752.
    View in: PubMed
  63. Hales CA, Kazemi H. Small-airways function in myocardial infarction. N Engl J Med. 1974 Apr 04; 290(14):761-5. PMID: 4815222.
    View in: PubMed
  64. Kazemi H, Hales CA. Pulmonary vascular response to unilateral alveolar hypoxia: role of H+. Bull Physiopathol Respir (Nancy). 1974 Mar-Apr; 10(2):267-72. PMID: 4415392.
    View in: PubMed
  65. Hoffer EP, Kanarek D, Kazemi H, Barnett GO. Computer interpretation of ventilatory studies. Comput Biomed Res. 1973 Aug; 6(4):347-54. PMID: 4582626.
    View in: PubMed
  66. Kazemi H, Shore NS, Shih VE, Shannon DC. Brain organic buffers in respiratory acidosis and alkalosis. J Appl Physiol. 1973 Apr; 34(4):478-82. PMID: 4698604.
    View in: PubMed
  67. Bruecke P, Burke JF, Lam KW, Shannon DC, Kazemi H. The pathophysiology of pulmonary fat embolism. J Thorac Cardiovasc Surg. 1971 Jun; 61(6):949-55. PMID: 5088585.
    View in: PubMed
  68. Valenca LM, Aisenberg AC, Kazemi H. Abnormalities of lung function in malignant lymphoma. Cancer. 1970 Jul; 26(1):154-61. PMID: 5424528.
    View in: PubMed
  69. Strieder DJ, Barnes BA, Aronow S, Russell PS, Kazemi H. Xenon 133 study of ventilation and perfusion in normal and transplanted dog lungs. J Appl Physiol. 1967 Sep; 23(3):359-66. PMID: 4860349.
    View in: PubMed
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