Harvard Catalyst Profiles

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Georges El Fakhri, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01EB027003 (EL FAKHRI, GEORGES) Sep 30, 2018 - Jun 30, 2023
    NIH/NIBIB
    Ultra High Resolution Brain PET Scanner for in-vivo Autoradiography Imaging
    Role: Principal Investigator
  2. P41EB022544 (EL FAKHRI, GEORGES) Sep 30, 2017 - Jun 30, 2022
    NIH/NIBIB
    Center for Molecular Imaging Technology and Translation (CMITT)
    Role: Principal Investigator
  3. R01HL137230 (EL FAKHRI, GEORGES) Sep 1, 2017 - Jun 30, 2021
    NIH/NHLBI
    PET/MR Mapping of Myocardial Membrane Potential
    Role: Principal Investigator
  4. R21EB021710 (EL FAKHRI, GEORGES) Jul 1, 2016 - Apr 30, 2018
    NIH/NIBIB
    PET/MRS guided radiotherapy
    Role: Principal Investigator
  5. S10OD018477 (EL FAKHRI, GEORGES) May 1, 2016 - Apr 30, 2017
    NIH
    Simultaneous Whole Body PET MR scanner.
    Role: Principal Investigator
This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.
MGH Gordon PET Core - Core services (4) and Instruments (8)

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Wooten DW, Ortiz-Terán L, Zubcevik N, Zhang X, Huang C, Sepulcre J, Atassi N, Johnson K, Zafonte R, El Fakhri G. Multimodal Signatures of Tau Pathology, Neuronal Fiber Integrity, and Functional Connectivity in Traumatic Brain Injury. J Neurotrauma. 2019 Jun 18. PMID: 31210098.
    Citations:    
  2. Putcha D, Brickhouse M, Touroutoglou A, Collins JA, Quimby M, Wong B, Eldaief M, Schultz A, El Fakhri G, Johnson K, Dickerson BC, McGinnis SM. Visual cognition in non-amnestic Alzheimer's disease: Relations to tau, amyloid, and cortical atrophy. Neuroimage Clin. 2019 Jun 04; 23:101889. PMID: 31200149.
    Citations:    
  3. Pan T, Einstein SA, Kappadath SC, Grogg KS, Lois Gomez C, Alessio AM, Hunter WC, El Fakhri G, Kinahan PE, Mawlawi OR. Performance evaluation of the 5-Ring GE Discovery MI PET/CT system using the national electrical manufacturers association NU 2-2012 Standard. Med Phys. 2019 May 09. PMID: 31069816.
    Citations:    
  4. Woo J, Xing F, Prince JL, Stone M, Green JR, Goldsmith T, Reese TG, Wedeen VJ, El Fakhri G. Differentiating post-cancer from healthy tongue muscle coordination patterns during speech using deep learning. J Acoust Soc Am. 2019 May; 145(5):EL423. PMID: 31153323.
    Citations:    
  5. Pizzagalli DA, Berretta S, Wooten D, Goer F, Pilobello KT, Kumar P, Murray L, Beltzer M, Boyer-Boiteau A, Alpert N, El Fakhri G, Mechawar N, Vitaliano G, Turecki G, Normandin M. Assessment of Striatal Dopamine Transporter Binding in Individuals With Major Depressive Disorder: In Vivo Positron Emission Tomography and Postmortem Evidence. JAMA Psychiatry. 2019 May 01. PMID: 31042280.
    Citations:    
  6. Bläckberg L, Sajedi S, Mandl S, Mohan A, Vittum B, El Fakhri G, Sabet H. Exploring light confinement in laser-processed LYSO:Ce for photon counting CT application. Phys Med Biol. 2019 Apr 29; 64(9):095020. PMID: 30897557.
    Citations:    
  7. Aguero C, Dhaynaut M, Normandin MD, Amaral AC, Guehl NJ, Neelamegam R, Marquie M, Johnson KA, El Fakhri G, Frosch MP, Gomez-Isla T. Autoradiography validation of novel tau PET tracer [F-18]-MK-6240 on human postmortem brain tissue. Acta Neuropathol Commun. 2019 Mar 11; 7(1):37. PMID: 30857558.
    Citations:    
  8. Pelletier-Galarneau M, Martineau P, El Fakhri G. Quantification of PET Myocardial Blood Flow. Curr Cardiol Rep. 2019 Feb 28; 21(3):11. PMID: 30815744.
    Citations:    
  9. Park GK, Lee JH, Levitz A, El Fakhri G, Hwang NS, Henary M, Choi HS. Lysosome-Targeted Bioprobes for Sequential Cell Tracking from Macroscopic to Microscopic Scales. Adv Mater. 2019 Apr; 31(14):e1806216. PMID: 30740778.
    Citations:    
  10. Kim K, Kim D, Yang J, El Fakhri G, Seo Y, Fessler JA, Li Q. Time of flight PET reconstruction using nonuniform update for regional recovery uniformity. Med Phys. 2019 Feb; 46(2):649-664. PMID: 30508255.
    Citations:    Fields:    
  11. Kaiser RH, Treadway MT, Wooten DW, Kumar P, Goer F, Murray L, Beltzer M, Pechtel P, Whitton A, Cohen AL, Alpert NM, El Fakhri G, Normandin MD, Pizzagalli DA. Frontostriatal and Dopamine Markers of Individual Differences in Reinforcement Learning: A Multi-modal Investigation. Cereb Cortex. 2018 Dec 01; 28(12):4281-4290. PMID: 29121332.
    Citations: 3     Fields:    
  12. Abdelbaky A, El Fakhri G, Tawakol A. Advances in coronary molecular imaging: Leveraging the power of image processing. J Nucl Cardiol. 2018 Oct 26. PMID: 30367381.
    Citations:    Fields:    
  13. Xin Q, Ortiz-Terán L, Diez I, Perez DL, Ginsburg J, El Fakhri G, Sepulcre J. Sequence Alterations of Cortical Genes Linked to Individual Connectivity of the Human Brain. Cereb Cortex. 2018 Oct 11. PMID: 30307489.
    Citations:    Fields:    
  14. Woo J, Prince JL, Stone M, Xing F, Gomez AD, Green JR, Hartnick CJ, Brady TJ, Reese TG, Wedeen VJ, El Fakhri G. A Sparse Non-negative Matrix Factorization Framework for Identifying Functional Units of Tongue Behavior from MRI. IEEE Trans Med Imaging. 2018 Sep 18. PMID: 30235120.
    Citations:    Fields:    
  15. Gong K, Guan J, Kim K, Zhang X, Yang J, Seo Y, El Fakhri G, Qi J, Li Q. Iterative PET Image Reconstruction Using Convolutional Neural Network Representation. IEEE Trans Med Imaging. 2018 Sep 12. PMID: 30222554.
    Citations:    Fields:    
  16. Kim K, Dutta J, Groll A, El Fakhri G, Meng LJ, Li Q. A novel depth-of-interaction rebinning strategy for ultrahigh resolution PET. Phys Med Biol. 2018 08 14; 63(16):165011. PMID: 30040073.
    Citations:    Fields:    
  17. Verwer EE, Kavanagh TR, Mischler WJ, Feng Y, Takahashi K, Wang S, Shoup TM, Neelamegam R, Yang J, Guehl NJ, Ran C, Massefski W, Cui Y, El-Chemaly S, Sadow PM, Oldham WM, Kijewski MF, El Fakhri G, Normandin MD, Priolo C. [18F]Fluorocholine and [18F]Fluoroacetate PET as Imaging Biomarkers to Assess Phosphatidylcholine and Mitochondrial Metabolism in Preclinical Models of TSC and LAM. Clin Cancer Res. 2018 Dec 01; 24(23):5925-5938. PMID: 30054282.
    Citations:    Fields:    
  18. Lai X, Petibon Y, El Fakhri G, Ouyang J. Joint reconstruction of rest/stress myocardial perfusion SPECT. Phys Med Biol. 2018 07 06; 63(13):135019. PMID: 29897044.
    Citations:    Fields:    
  19. Gong K, Yang J, Kim K, El Fakhri G, Seo Y, Li Q. Attenuation correction for brain PET imaging using deep neural network based on Dixon and ZTE MR images. Phys Med Biol. 2018 06 13; 63(12):125011. PMID: 29790857.
    Citations:    Fields:    
  20. Kim K, Wu D, Gong K, Dutta J, Kim JH, Son YD, Kim HK, El Fakhri G, Li Q. Penalized PET Reconstruction Using Deep Learning Prior and Local Linear Fitting. IEEE Trans Med Imaging. 2018 06; 37(6):1478-1487. PMID: 29870375.
    Citations:    Fields:    
  21. Hu S, Kang H, Baek Y, El Fakhri G, Kuang A, Choi HS. Real-Time Imaging of Brain Tumor for Image-Guided Surgery. Adv Healthc Mater. 2018 Aug; 7(16):e1800066. PMID: 29719137.
    Citations: 1     Fields:    
  22. Lee E, Xing F, Ahn S, Reese TG, Wang R, Green JR, Atassi N, Wedeen VJ, El Fakhri G, Woo J. Magnetic resonance imaging based anatomical assessment of tongue impairment due to amyotrophic lateral sclerosis: A preliminary study. J Acoust Soc Am. 2018 Apr; 143(4):EL248. PMID: 29716267.
    Citations:    Fields:    
  23. Xing F, Prince JL, Stone M, Reese TG, Atassi N, Wedeen VJ, El Fakhri G, Woo J. Strain Map of the Tongue in Normal and ALS Speech Patterns from Tagged and Diffusion MRI. Proc SPIE Int Soc Opt Eng. 2018 Feb; 10574. PMID: 29706684.
    Citations:    
  24. Chang Y, Sharp GC, Li Q, Shih HA, El Fakhri G, Ra JB, Woo J. Subject-specific Brain Tumor Growth Modelling via An Efficient Bayesian Inference Framework. Proc SPIE Int Soc Opt Eng. 2018 Feb; 10574. PMID: 30050231.
    Citations:    
  25. Guo R, Petibon Y, Ma Y, El Fakhri G, Ying K, Ouyang J. MR-based motion correction for cardiac PET parametric imaging: a simulation study. EJNMMI Phys. 2018 Feb 01; 5(1):3. PMID: 29388075.
    Citations:    
  26. Yuan H, Wilks MQ, Normandin MD, El Fakhri G, Kaittanis C, Josephson L. Heat-induced radiolabeling and fluorescence labeling of Feraheme nanoparticles for PET/SPECT imaging and flow cytometry. Nat Protoc. 2018 02; 13(2):392-412. PMID: 29370158.
    Citations: 1     Fields:    
  27. Alpert NM, Guehl N, Ptaszek L, Pelletier-Galarneau M, Ruskin J, Mansour MC, Wooten D, Ma C, Takahashi K, Zhou Y, Shoup TM, Normandin MD, El Fakhri G. Quantitative in vivo mapping of myocardial mitochondrial membrane potential. PLoS One. 2018; 13(1):e0190968. PMID: 29338024.
    Citations: 2     Fields:    Translation:Animals
  28. Wada H, Hyun H, Bao K, Lee JH, El Fakhri G, Choi Y, Choi HS. Multivalent Mannose-Decorated NIR Nanoprobes for Targeting Pan Lymph Nodes. Chem Eng J. 2018 May 15; 340:51-57. PMID: 29962899.
    Citations:    
  29. Fahey FH, Grogg K, El Fakhri G. Use of Monte Carlo Techniques in Nuclear Medicine. J Am Coll Radiol. 2018 03; 15(3 Pt A):446-448. PMID: 29173989.
    Citations:    Fields:    Translation:Humans
  30. Bläckberg L, El Fakhri G, Sabet H. Simulation study of light transport in laser-processed LYSO:Ce detectors with single-side readout. Phys Med Biol. 2017 Oct 19; 62(21):8419-8440. PMID: 29047453.
    Citations: 1     Fields:    
  31. Sîrbulescu RF, Boehm CK, Soon E, Wilks MQ, Ilies I, Yuan H, Maxner B, Chronos N, Kaittanis C, Normandin MD, El Fakhri G, Orgill DP, Sluder AE, Poznansky MC. Mature B cells accelerate wound healing after acute and chronic diabetic skin lesions. Wound Repair Regen. 2017 09; 25(5):774-791. PMID: 28922523.
    Citations: 2     Fields:    Translation:AnimalsCells
  32. Kim K, El Fakhri G, Li Q. Low-dose CT reconstruction using spatially encoded nonlocal penalty. Med Phys. 2017 Oct; 44(10):e376-e390. PMID: 29027240.
    Citations:    Fields:    Translation:Humans
  33. Blackberg L, El Fakhri G, Sabet H. Simulation study of light transport in laser-processed LYSO:Ce detectors with single-side readout. Phys Med Biol. 2017 Sep 20. PMID: 28930096.
    Citations:    Fields:    
  34. Wu D, Kim K, El Fakhri G, Li Q. Iterative Low-Dose CT Reconstruction With Priors Trained by Artificial Neural Network. IEEE Trans Med Imaging. 2017 12; 36(12):2479-2486. PMID: 28922116.
    Citations: 2     Fields:    Translation:Humans
  35. Han PK, Ma C, Deng K, Hu S, Jee KW, Ying K, Chen YL, El Fakhri G. A minimum-phase Shinnar-Le Roux spectral-spatial excitation RF pulse for simultaneous water and lipid suppression in 1H-MRSI of body extremities. Magn Reson Imaging. 2018 01; 45:18-25. PMID: 28917812.
    Citations:    Fields:    Translation:Humans
  36. Guehl NJ, Normandin MD, Wooten DW, Rozen G, Ruskin JN, Shoup TM, Woo J, Ptaszek LM, Fakhri GE, Alpert NM. Rapid computation of single PET scan rest-stress myocardial blood flow parametric images by table look up. Med Phys. 2017 Sep; 44(9):4643-4651. PMID: 28594441.
    Citations:    Fields:    Translation:HumansAnimals
  37. Rakvongthai Y, El Fakhri G. Magnetic Resonance-based Motion Correction for Quantitative PET in Simultaneous PET-MR Imaging. PET Clin. 2017 Jul; 12(3):321-327. PMID: 28576170.
    Citations:    Fields:    Translation:Humans
  38. Sepulcre J, Grothe MJ, Sabuncu M, Chhatwal J, Schultz AP, Hanseeuw B, El Fakhri G, Sperling R, Johnson KA. Hierarchical Organization of Tau and Amyloid Deposits in the Cerebral Cortex. JAMA Neurol. 2017 07 01; 74(7):813-820. PMID: 28558094.
    Citations: 8     Fields:    Translation:Humans
  39. Ortiz-Terán L, Diez I, Ortiz T, Perez DL, Aragón JI, Costumero V, Pascual-Leone A, El Fakhri G, Sepulcre J. Brain circuit-gene expression relationships and neuroplasticity of multisensory cortices in blind children. Proc Natl Acad Sci U S A. 2017 06 27; 114(26):6830-6835. PMID: 28607055.
    Citations:    Fields:    Translation:HumansCTClinical Trials
  40. Collier TL, Normandin MD, Stephenson NA, Livni E, Liang SH, Wooten DW, Esfahani SA, Stabin MG, Mahmood U, Chen J, Wang W, Maresca K, Waterhouse RN, El Fakhri G, Richardson P, Vasdev N. Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib. Nat Commun. 2017 06 08; 8:15761. PMID: 28594000.
    Citations: 4     Fields:    Translation:HumansAnimals
  41. Li Q, Li H, Kim K, El Fakhri G. Joint estimation of activity image and attenuation sinogram using time-of-flight positron emission tomography data consistency condition filtering. J Med Imaging (Bellingham). 2017 Apr; 4(2):023502. PMID: 28466027.
    Citations: 1     
  42. Petibon Y, Rakvongthai Y, El Fakhri G, Ouyang J. Direct parametric reconstruction in dynamic PET myocardial perfusion imaging: in vivo studies. Phys Med Biol. 2017 05 07; 62(9):3539-3565. PMID: 28379843.
    Citations:    Fields:    Translation:Animals
  43. Rakvongthai Y, Fahey F, Borvorntanajanya K, Tepmongkol S, Vutrapongwatana U, Zukotynski K, El Fakhri G, Ouyang J. Joint reconstruction of Ictal/inter-ictal SPECT data for improved epileptic foci localization. Med Phys. 2017 Apr; 44(4):1437-1444. PMID: 28211105.
    Citations: 1     Fields:    Translation:Humans
  44. Guehl NJ, Normandin MD, Wooten DW, Rozen G, Sitek A, Ruskin J, Shoup TM, Ptaszek LM, El Fakhri G, Alpert NM. Single-scan rest/stress imaging: validation in a porcine model with 18F-Flurpiridaz. Eur J Nucl Med Mol Imaging. 2017 Aug; 44(9):1538-1546. PMID: 28365789.
    Citations: 3     Fields:    Translation:Animals
  45. Cho J, Grogg K, Min CH, Zhu X, Paganetti H, Lee HC, El Fakhri G. Feasibility study of using fall-off gradients of early and late PET scans for proton range verification. Med Phys. 2017 May; 44(5):1734-1746. PMID: 28273345.
    Citations:    Fields:    Translation:Humans
  46. Sepulcre J, Sabuncu MR, Li Q, El Fakhri G, Sperling R, Johnson KA. Tau and amyloid ß proteins distinctively associate to functional network changes in the aging brain. Alzheimers Dement. 2017 Nov; 13(11):1261-1269. PMID: 28366797.
    Citations: 6     Fields:    Translation:Humans
  47. Yuan H, Wilks MQ, El Fakhri G, Normandin MD, Kaittanis C, Josephson L. Heat-induced-radiolabeling and click chemistry: A powerful combination for generating multifunctional nanomaterials. PLoS One. 2017; 12(2):e0172722. PMID: 28225818.
    Citations: 4     Fields:    
  48. Neelamegam R, Yokell DL, Rice PA, Furumoto S, Kudo Y, Okamura N, El Fakhri G. A report of the automated radiosynthesis of the tau positron emission tomography radiopharmaceutical, [18 F]-THK-5351. J Labelled Comp Radiopharm. 2017 02; 60(2):140-146. PMID: 27859483.
    Citations: 1     Fields:    
  49. Bao K, Lee JH, Kang H, Park GK, El Fakhri G, Choi HS. PSMA-targeted contrast agents for intraoperative imaging of prostate cancer. Chem Commun (Camb). 2017 Feb 04; 53(10):1611-1614. PMID: 28085163.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  50. Petibon Y, Guehl NJ, Reese TG, Ebrahimi B, Normandin MD, Shoup TM, Alpert NM, El Fakhri G, Ouyang J. Impact of motion and partial volume effects correction on PET myocardial perfusion imaging using simultaneous PET-MR. Phys Med Biol. 2017 01 21; 62(2):326-343. PMID: 27997375.
    Citations: 4     Fields:    Translation:Animals
  51. Choi NC, Gainor J, Ackman J, Lim R, Sharp GC, El Fakhri G, Niemierko A. ORAL02.03: Robust Correlation Between Metabolic Response Measured with 18F-FDG PET Soon After Therapy and Clinical Outcome in Lung Cancer: Topic: Radiation Oncology. J Thorac Oncol. 2016 11; 11(11S):S253-S254. PMID: 27969446.
    Citations:    Fields:    
  52. Sitek A, Li Q, El Fakhri G, Alpert NM. Validation of Bayesian analysis of compartmental kinetic models in medical imaging. Phys Med. 2016 Oct; 32(10):1252-1258. PMID: 27692754.
    Citations:    Fields:    Translation:Humans
  53. Wooten DW, Guehl NJ, Verwer EE, Shoup TM, Yokell DL, Zubcevik N, Vasdev N, Zafonte RD, Johnson KA, El Fakhri G, Normandin MD. Pharmacokinetic Evaluation of the Tau PET Radiotracer 18F-T807 (18F-AV-1451) in Human Subjects. J Nucl Med. 2017 Mar; 58(3):484-491. PMID: 27660144.
    Citations: 13     Fields:    Translation:Humans
  54. Koo H, Lee JH, Bao K, Wu Y, El Fakhri G, Henary M, Yun SH, Choi HS. Site-Specific In Vivo Bioorthogonal Ligation via Chemical Modulation. Adv Healthc Mater. 2016 10; 5(19):2510-2516. PMID: 27568818.
    Citations: 1     Fields:    Translation:AnimalsCells
  55. Owens EA, Henary M, El Fakhri G, Choi HS. Tissue-Specific Near-Infrared Fluorescence Imaging. Acc Chem Res. 2016 09 20; 49(9):1731-40. PMID: 27564418.
    Citations: 9     Fields:    Translation:Humans
  56. Ashitate Y, Levitz A, Park MH, Hyun H, Venugopal V, Park G, El Fakhri G, Henary M, Gioux S, Frangioni JV, Choi HS. Endocrine-specific NIR fluorophores for adrenal gland targeting. Chem Commun (Camb). 2016 Aug 11; 52(67):10305-8. PMID: 27476533.
    Citations: 4     Fields:    Translation:Humans
  57. Kang H, Gravier J, Bao K, Wada H, Lee JH, Baek Y, El Fakhri G, Gioux S, Rubin BP, Coll JL, Choi HS. Renal Clearable Organic Nanocarriers for Bioimaging and Drug Delivery. Adv Mater. 2016 Oct; 28(37):8162-8168. PMID: 27414255.
    Citations: 2     Fields:    
  58. Liang SH, Chen JM, Normandin MD, Chang JS, Chang GC, Taylor CK, Trapa P, Plummer MS, Para KS, Conn EL, Lopresti-Morrow L, Lanyon LF, Cook JM, Richter KE, Nolan CE, Schachter JB, Janat F, Che Y, Shanmugasundaram V, Lefker BA, Enerson BE, Livni E, Wang L, Guehl NJ, Patnaik D, Wagner FF, Perlis R, Holson EB, Haggarty SJ, El Fakhri G, Kurumbail RG, Vasdev N. Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging. Angew Chem Int Ed Engl. 2016 08 08; 55(33):9601-5. PMID: 27355874.
    Citations: 5     Fields:    Translation:HumansCells
  59. Bian J, Sharp GC, Park YK, Ouyang J, Bortfeld T, El Fakhri G. Investigation of cone-beam CT image quality trade-off for image-guided radiation therapy. Phys Med Biol. 2016 May 07; 61(9):3317-46. PMID: 27032676.
    Citations: 2     Fields:    Translation:Humans
  60. Zhu W, Ouyang J, Rakvongthai Y, Guehl NJ, Wooten DW, El Fakhri G, Normandin MD, Fan Y. A Bayesian spatial temporal mixtures approach to kinetic parametric images in dynamic positron emission tomography. Med Phys. 2016 Mar; 43(3):1222-34. PMID: 26936707.
    Citations:    Fields:    Translation:Animals
  61. Wang M, Guo N, Hu G, El Fakhri G, Zhang H, Li Q. A novel approach to assess the treatment response using Gaussian random field in PET. Med Phys. 2016 Feb; 43(2):833-42. PMID: 26843244.
    Citations: 1     Fields:    
  62. Grogg KS, Toole T, Ouyang J, Zhu X, Normandin MD, Li Q, Johnson K, Alpert NM, El Fakhri G. National Electrical Manufacturers Association and Clinical Evaluation of a Novel Brain PET/CT Scanner. J Nucl Med. 2016 Apr; 57(4):646-52. PMID: 26697961.
    Citations:    Fields:    Translation:HumansAnimals
  63. Zhang X, Chen YL, Lim R, Huang C, Chebib IA, El Fakhri G. Synergistic role of simultaneous PET/MRI-MRS in soft tissue sarcoma metabolism imaging. Magn Reson Imaging. 2016 Apr; 34(3):276-9. PMID: 26523656.
    Citations: 2     Fields:    Translation:Humans
  64. Huang C, Ouyang J, Reese TG, Wu Y, El Fakhri G, Ackerman JL. Continuous MR bone density measurement using water- and fat-suppressed projection imaging (WASPI) for PET attenuation correction in PET-MR. Phys Med Biol. 2015 Oct 21; 60(20):N369-81. PMID: 26405761.
    Citations: 1     Fields:    Translation:Humans
  65. Normandin MD, Yuan H, Wilks MQ, Chen HH, Kinsella JM, Cho H, Guehl NJ, Absi-Halabi N, Hosseini SM, El Fakhri G, Sosnovik DE, Josephson L. Heat-Induced Radiolabeling of Nanoparticles for Monocyte Tracking by PET. Angew Chem Int Ed Engl. 2015 Oct 26; 54(44):13002-6. PMID: 26368132.
    Citations: 4     Fields:    Translation:AnimalsCells
  66. Dutta J, Huang C, Li Q, El Fakhri G. Pulmonary imaging using respiratory motion compensated simultaneous PET/MR. Med Phys. 2015 Jul; 42(7):4227-40. PMID: 26133621.
    Citations: 2     Fields:    Translation:Humans
  67. Paganetti H, El Fakhri G. Monitoring proton therapy with PET. Br J Radiol. 2015 Jul; 88(1051):20150173. PMID: 25989699.
    Citations:    Fields:    Translation:HumansPHPublic Health
  68. Wilks MQ, Normandin MD, Yuan H, Cho H, Guo Y, Herisson F, Ayata C, Wooten DW, El Fakhri G, Josephson L. Imaging PEG-like nanoprobes in tumor, transient ischemia, and inflammatory disease models. Bioconjug Chem. 2015 Jun 17; 26(6):1061-9. PMID: 25971846.
    Citations: 1     Fields:    Translation:AnimalsCells
  69. Grogg K, Alpert NM, Zhu X, Min CH, Testa M, Winey B, Normandin MD, Shih HA, Paganetti H, Bortfeld T, El Fakhri G. Mapping (15)O production rate for proton therapy verification. Int J Radiat Oncol Biol Phys. 2015 Jun 01; 92(2):453-9. PMID: 25817530.
    Citations: 2     Fields:    Translation:AnimalsCells
  70. Huang C, Petibon Y, Ouyang J, Reese TG, Ahlman MA, Bluemke DA, El Fakhri G. Accelerated acquisition of tagged MRI for cardiac motion correction in simultaneous PET-MR: phantom and patient studies. Med Phys. 2015 Feb; 42(2):1087-97. PMID: 25652521.
    Citations: 6     Fields:    Translation:Humans
  71. Kim K, Ye JC, Worstell W, Ouyang J, Rakvongthai Y, El Fakhri G, Li Q. Sparse-view spectral CT reconstruction using spectral patch-based low-rank penalty. IEEE Trans Med Imaging. 2015 Mar; 34(3):748-60. PMID: 25532170.
    Citations: 8     Fields:    Translation:Humans
  72. Ouyang J, Petibon Y, Huang C, Reese TG, Kolnick AL, El Fakhri G. Quantitative simultaneous positron emission tomography and magnetic resonance imaging. J Med Imaging (Bellingham). 2014 Oct; 1(3):033502. PMID: 26158055.
    Citations: 2     
  73. Lorsakul A, Li Q, Trott CM, Hoog C, Petibon Y, Ouyang J, Laine AF, El Fakhri G. 4D numerical observer for lesion detection in respiratory-gated PET. Med Phys. 2014 Oct; 41(10):102504. PMID: 25281979.
    Citations:    Fields:    Translation:Humans
  74. Min CH, Zhu X, Grogg K, El Fakhri G, Winey B, Paganetti H. A Recommendation on How to Analyze In-Room PET for In Vivo Proton Range Verification Using a Distal PET Surface Method. Technol Cancer Res Treat. 2015 Jun; 14(3):320-5. PMID: 25246517.
    Citations: 1     Fields:    Translation:Humans
  75. Rakvongthai Y, Worstell W, El Fakhri G, Bian J, Lorsakul A, Ouyang J. Spectral CT using multiple balanced K-edge filters. IEEE Trans Med Imaging. 2015 Mar; 34(3):740-7. PMID: 25252276.
    Citations: 1     Fields:    Translation:HumansCells
  76. Schaefferkoetter J, Ouyang J, Rakvongthai Y, Nappi C, El Fakhri G. Effect of time-of-flight and point spread function modeling on detectability of myocardial defects in PET. Med Phys. 2014 Jun; 41(6):062502. PMID: 24877836.
    Citations: 5     Fields:    Translation:Humans
  77. Huang C, Altbach MI, El Fakhri G. Pattern recognition for rapid T2 mapping with stimulated echo compensation. Magn Reson Imaging. 2014 Sep; 32(7):969-74. PMID: 24853466.
    Citations: 1     Fields:    Translation:Humans
  78. Petibon Y, Huang C, Ouyang J, Reese TG, Li Q, Syrkina A, Chen YL, El Fakhri G. Relative role of motion and PSF compensation in whole-body oncologic PET-MR imaging. Med Phys. 2014 Apr; 41(4):042503. PMID: 24694156.
    Citations: 5     Fields:    Translation:Humans
  79. Huang C, Ackerman JL, Petibon Y, Brady TJ, El Fakhri G, Ouyang J. MR-based motion correction for PET imaging using wired active MR microcoils in simultaneous PET-MR: phantom study. Med Phys. 2014 Apr; 41(4):041910. PMID: 24694141.
    Citations: 2     Fields:    
  80. Petibon Y, El Fakhri G, Nezafat R, Johnson N, Brady T, Ouyang J. Towards coronary plaque imaging using simultaneous PET-MR: a simulation study. Phys Med Biol. 2014 Mar 07; 59(5):1203-22. PMID: 24556608.
    Citations: 9     Fields:    Translation:Humans
  81. Mananga ES, El Fakhri G, Schaefferkoetter J, Bonab AA, Ouyang J. Myocardial defect detection using PET-CT: phantom studies. PLoS One. 2014; 9(2):e88200. PMID: 24505429.
    Citations: 3     Fields:    Translation:Humans
  82. Huang C, Ackerman JL, Petibon Y, Normandin MD, Brady TJ, El Fakhri G, Ouyang J. Motion compensation for brain PET imaging using wireless MR active markers in simultaneous PET-MR: phantom and non-human primate studies. Neuroimage. 2014 May 01; 91:129-37. PMID: 24418501.
    Citations: 5     Fields:    Translation:HumansAnimals
  83. Liang SH, Yokell DL, Normandin MD, Rice PA, Jackson RN, Shoup TM, Brady TJ, El Fakhri G, Collier TL, Vasdev N. First human use of a radiopharmaceutical prepared by continuous-flow microfluidic radiofluorination: proof of concept with the tau imaging agent [18F]T807. Mol Imaging. 2014; 13. PMID: 25248283.
    Citations: 2     Fields:    Translation:Humans
  84. Hu C, El Fakhri G, Li Q. Evaluating structural symmetry of weighted brain networks via graph matching. Med Image Comput Comput Assist Interv. 2014; 17(Pt 2):733-40. PMID: 25485445.
    Citations: 1     Fields:    Translation:Humans
  85. El Fakhri G, Trott CM, Sitek A, Bonab A, Alpert NM. Dual-tracer PET using generalized factor analysis of dynamic sequences. Mol Imaging Biol. 2013 Dec; 15(6):666-74. PMID: 23636489.
    Citations: 4     Fields:    Translation:HumansAnimals
  86. Rakvongthai Y, El Fakhri G, Lim R, Bonab AA, Ouyang J. Simultaneous 99mTc-MDP/123I-MIBG tumor imaging using SPECT-CT: phantom and constructed patient studies. Med Phys. 2013 Oct; 40(10):102506. PMID: 24089927.
    Citations: 1     Fields:    Translation:Humans
  87. Rakvongthai Y, Ouyang J, Guerin B, Li Q, Alpert NM, El Fakhri G. Direct reconstruction of cardiac PET kinetic parametric images using a preconditioned conjugate gradient approach. Med Phys. 2013 Oct; 40(10):102501. PMID: 24089922.
    Citations: 3     Fields:    
  88. Grogg K, Zhu X, Min CH, Winey B, Bortfeld T, Paganetti H, Shih HA, El Fakhri G. Feasibility of Using Distal Endpoints for In-room PET Range Verification of Proton Therapy. IEEE Trans Nucl Sci. 2013 Oct; 60(5):3290-3297. PMID: 24464031.
    Citations: 1     
  89. Zhu X, El Fakhri G. Proton therapy verification with PET imaging. Theranostics. 2013 Sep 19; 3(10):731-40. PMID: 24312147.
    Citations: 4     Fields:    Translation:Humans
  90. Nappi C, El Fakhri G. State of the Art in Cardiac Hybrid Technology: PET/MR. Curr Cardiovasc Imaging Rep. 2013 Aug 01; 6(4):338-345. PMID: 24073295.
    Citations: 6     
  91. Cho J, Ibbott G, Gillin M, Gonzalez-Lepera C, Min CH, Zhu X, El Fakhri G, Paganetti H, Mawlawi O. Determination of elemental tissue composition following proton treatment using positron emission tomography. Phys Med Biol. 2013 Jun 07; 58(11):3815-35. PMID: 23681070.
    Citations: 4     Fields:    Translation:Humans
  92. Gilmore CD, Comeau CR, Alessi AM, Blaine M, El Fakhri GN, Hunt JK, Jordan DW, King BJ, Sicignano AJ, Stanley CT, Timpe JT, Wenzel-Lamb N. PET/MR imaging consensus paper: a joint paper by the Society of Nuclear Medicine and Molecular Imaging Technologist Section and the Section for Magnetic Resonance Technologists. J Nucl Med Technol. 2013 Jun; 41(2):108-13. PMID: 23633561.
    Citations: 2     Fields:    Translation:Humans
  93. Petibon Y, Ouyang J, Zhu X, Huang C, Reese TG, Chun SY, Li Q, El Fakhri G. Cardiac motion compensation and resolution modeling in simultaneous PET-MR: a cardiac lesion detection study. Phys Med Biol. 2013 Apr 07; 58(7):2085-102. PMID: 23470288.
    Citations: 18     Fields:    Translation:Humans
  94. Schaefferkoetter J, Casey M, Townsend D, El Fakhri G. Clinical impact of time-of-flight and point response modeling in PET reconstructions: a lesion detection study. Phys Med Biol. 2013 Mar 07; 58(5):1465-78. PMID: 23403399.
    Citations: 14     Fields:    Translation:Humans
  95. Min CH, Zhu X, Winey BA, Grogg K, Testa M, El Fakhri G, Bortfeld TR, Paganetti H, Shih HA. Clinical application of in-room positron emission tomography for in vivo treatment monitoring in proton radiation therapy. Int J Radiat Oncol Biol Phys. 2013 May 01; 86(1):183-9. PMID: 23391817.
    Citations: 13     Fields:    Translation:Humans
  96. Hu C, Cheng L, Sepulcre J, El Fakhri G, Lu YM, Lu YM. Matched signal detection on graphs: theory and application to brain network classification. Inf Process Med Imaging. 2013; 23:1-12. PMID: 24683953.
    Citations: 1     Fields:    Translation:Humans
  97. Ouyang J, Li Q, El Fakhri G. Magnetic resonance-based motion correction for positron emission tomography imaging. Semin Nucl Med. 2013 Jan; 43(1):60-7. PMID: 23178089.
    Citations: 18     Fields:    Translation:HumansAnimals
  98. Alpert N, Dean Fang YH, El Fakhri G. Single-scan rest/stress imaging (18)F-labeled flow tracers. Med Phys. 2012 Nov; 39(11):6609-20. PMID: 23127055.
    Citations: 8     Fields:    Translation:Humans
  99. Chun SY, Reese TG, Ouyang J, Guerin B, Catana C, Zhu X, Alpert NM, El Fakhri G. MRI-based nonrigid motion correction in simultaneous PET/MRI. J Nucl Med. 2012 Aug; 53(8):1284-91. PMID: 22743250.
    Citations: 28     Fields:    Translation:Animals
  100. Fang YH, El Fakhri G, Becker JA, Alpert NM. Parametric imaging with Bayesian priors: a validation study with (11)C-Altropane PET. Neuroimage. 2012 May 15; 61(1):131-8. PMID: 22425668.
    Citations: 1     Fields:    Translation:Humans
  101. Zhu X, España S, Daartz J, Liebsch N, Ouyang J, Paganetti H, Bortfeld TR, El Fakhri G. Monitoring proton radiation therapy with in-room PET imaging. Phys Med Biol. 2011 Jul 07; 56(13):4041-57. PMID: 21677366.
    Citations: 16     Fields:    Translation:Humans
  102. Guérin B, Cho S, Chun SY, Zhu X, Alpert NM, Reese T, Catana C., El Fakhri G,. Med Phys. Nonrigid PET motion compensation in the lower abdomen using simultaneous tagged-MRI and PET imaging. 2011; 38(6):3025-38.
  103. Surti S, Scheuermann J, El Fakhri G, Daube-Witherspoon ME, Lim R, Abi-Hatem N, Moussallem E, Benard F, Mankoff D, Karp JS. Impact of time-of-flight PET on whole-body oncologic studies: a human observer lesion detection and localization study. J Nucl Med. 2011 May; 52(5):712-9. PMID: 21498523.
    Citations: 25     Fields:    Translation:Humans
  104. España S, Zhu X, Daartz J, El Fakhri G, Bortfeld T, Paganetti H. The reliability of proton-nuclear interaction cross-section data to predict proton-induced PET images in proton therapy. Phys Med Biol. 2011 May 07; 56(9):2687-98. PMID: 21464534.
    Citations: 12     Fields:    Translation:Humans
  105. El Fakhri G, Surti S, Trott CM, Scheuermann J, Karp JS. Improvement in lesion detection with whole-body oncologic time-of-flight PET. J Nucl Med. 2011 Mar; 52(3):347-53. PMID: 21321265.
    Citations: 46     Fields:    Translation:Humans
  106. El Fakhri G, Ouyang J. Dual-radionuclide brain SPECT for the differential diagnosis of parkinsonism. Methods Mol Biol. 2011; 680:237-46. PMID: 21153385.
    Citations: 1     Fields:    Translation:Humans
  107. Catana C, Benner T, van der Kouwe A, Byars L, Hamm M, Chonde DB, Michel CJ, El Fakhri G, Schmand M, Sorensen AG. MRI-assisted PET motion correction for neurologic studies in an integrated MR-PET scanner. J Nucl Med. 2011 Jan; 52(1):154-61. PMID: 21189415.
    Citations: 38     Fields:    Translation:Humans
  108. Guérin B, El Fakhri G. Novel scatter compensation of list-mode PET data using spatial and energy dependent corrections. IEEE Trans Med Imaging. 2011 Mar; 30(3):759-73. PMID: 21118770.
    Citations:    Fields:    
  109. Trott CM, Ouyang J, El Fakhri G. Comparison of simultaneous and sequential SPECT imaging for discrimination tasks in assessment of cardiac defects. Phys Med Biol. 2010 Nov 21; 55(22):6897-910. PMID: 21048290.
    Citations:    Fields:    Translation:Humans
  110. Zhu X, Reese TG, Crowley EM, El Fakhri G. Improved MAGIC gel for higher sensitivity and elemental tissue equivalent 3D dosimetry. Med Phys. 2010 Jan; 37(1):183-8. PMID: 20175480.
    Citations:    Fields:    
  111. Zhu X, El Fakhri G. Monte Carlo modeling of cascade gamma rays in (86)Y PET imaging: preliminary results. Phys Med Biol. 2009 Jul 07; 54(13):4181-93. PMID: 19521011.
    Citations: 3     Fields:    Translation:Humans
  112. El Fakhri G, Kardan A, Sitek A, Dorbala S, Abi-Hatem N, Lahoud Y, Fischman A, Coughlan M, Yasuda T, Di Carli MF. Reproducibility and accuracy of quantitative myocardial blood flow assessment with (82)Rb PET: comparison with (13)N-ammonia PET. J Nucl Med. 2009 Jul; 50(7):1062-71. PMID: 19525467.
    Citations: 78     Fields:    Translation:Humans
  113. Curillova Z, Yaman BF, Dorbala S, Kwong RY, Sitek A, El Fakhri G, Anagnostopoulos C, Di Carli MF. Quantitative relationship between coronary calcium content and coronary flow reserve as assessed by integrated PET/CT imaging. Eur J Nucl Med Mol Imaging. 2009 Oct; 36(10):1603-10. PMID: 19387640.
    Citations: 13     Fields:    Translation:Humans
  114. Ouyang J, Zhu X, Trott CM, El Fakhri G. Quantitative simultaneous 99mTc/123I cardiac SPECT using MC-JOSEM. Med Phys. 2009 Feb; 36(2):602-11. PMID: 19292000.
    Citations: 9     Fields:    
  115. Zaidi H, El Fakhri G. Is absolute quantification of dopaminergic neurotransmission studies with 123I SPECT ready for clinical use? Eur J Nucl Med Mol Imaging. 2008 Jul; 35(7):1330-3. PMID: 18523768.
    Citations: 3     Fields:    Translation:HumansCells
  116. Trott CM, El Fakhri G. Sequential and simultaneous dual-isotope brain SPECT: comparison with PET for estimation and discrimination tasks in early Parkinson disease. Med Phys. 2008 Jul; 35(7):3343-53. PMID: 18697558.
    Citations: 2     Fields:    Translation:HumansAnimals
  117. Trott CM, El Fakhri G. Sequential and simultaneous dual-isotope brain SPECT: Comparison with PET for estimation and discrimination tasks in early Parkinson disease. Med Phys. 2008 Jul; 35(7Part1):3343-3353. PMID: 28513019.
    Citations:    
  118. Ouyang J, El Fakhri G, Moore SC. Improved activity estimation with MC-JOSEM versus TEW-JOSEM in 111In SPECT. Med Phys. 2008 May; 35(5):2029-40. PMID: 18561679.
    Citations: 2     Fields:    
  119. Anagnostopoulos C, Almonacid A, El Fakhri G, Curillova Z, Sitek A, Roughton M, Dorbala S, Popma JJ, Di Carli MF. Quantitative relationship between coronary vasodilator reserve assessed by 82Rb PET imaging and coronary artery stenosis severity. Eur J Nucl Med Mol Imaging. 2008 Sep; 35(9):1593-601. PMID: 18425513.
    Citations: 20     Fields:    Translation:Humans
  120. Mamede M, El Fakhri G, Abreu-e-Lima P, Gandler W, Nosé V, Gerbaudo VH. Pre-operative estimation of esophageal tumor metabolic length in FDG-PET images with surgical pathology confirmation. Ann Nucl Med. 2007 Dec; 21(10):553-62. PMID: 18092131.
    Citations: 13     Fields:    Translation:Humans
  121. El Fakhri G, Santos PA, Badawi RD, Holdsworth CH, Van Den Abbeele AD, Kijewski MF. Impact of acquisition geometry, image processing, and patient size on lesion detection in whole-body 18F-FDG PET. J Nucl Med. 2007 Dec; 48(12):1951-60. PMID: 18006613.
    Citations: 15     Fields:    Translation:Humans
  122. Kas A, Payoux P, Habert MO, Malek Z, Cointepas Y, El Fakhri G, Chaumet-Riffaud P, Itti E, Remy P. Validation of a standardized normalization template for statistical parametric mapping analysis of 123I-FP-CIT images. J Nucl Med. 2007 Sep; 48(9):1459-67. PMID: 17704252.
    Citations: 16     Fields:    Translation:Humans
  123. Ouyang J, El Fakhri G, Moore SC. Fast Monte Carlo based joint iterative reconstruction for simultaneous 99mTc/ 123I SPECT imaging. Med Phys. 2007 Aug; 34(8):3263-72. PMID: 17879789.
    Citations: 13     Fields:    Translation:Humans
  124. Ouyang J, El Fakhri G, Moore SC. Fast Monte Carlo based joint iterative reconstruction for simultaneous Tc99m/I123 SPECT imaging. Med Phys. 2007 Aug; 34(8):3263-3272. PMID: 28523655.
    Citations:    
  125. Di Carli MF, Dorbala S, Meserve J, El Fakhri G, Sitek A, Moore SC. Clinical myocardial perfusion PET/CT. J Nucl Med. 2007 May; 48(5):783-93. PMID: 17475968.
    Citations: 74     Fields:    Translation:Humans
  126. Habert MO, Lacomblez L, Maksud P, El Fakhri G, Pradat JF, Meininger V. Brain perfusion imaging in amyotrophic lateral sclerosis: extent of cortical changes according to the severity and topography of motor impairment. Amyotroph Lateral Scler. 2007 Feb; 8(1):9-15. PMID: 17364429.
    Citations: 10     Fields:    Translation:Humans
  127. El Fakhri G, Sitek A, Zimmerman RE, Ouyang J. Generalized five-dimensional dynamic and spectral factor analysis. Med Phys. 2006 Apr; 33(4):1016-24. PMID: 16696478.
    Citations: 8     Fields:    Translation:HumansAnimals
  128. Kijewski MF, Mueller SP, El Fakhri G. Estimation of time-varying dual-tracer striatal activity from simultaneously acquired SPECT data. J. Nucl. Med. 2006; 47.
  129. El Fakhri G, Ouyang J, Zimmerman RE, Fischman AJ, Kijewski MF. Performance of a novel collimator for high-sensitivity brain SPECT. Med Phys. 2006 Jan; 33(1):209-15. PMID: 16485427.
    Citations: 2     Fields:    Translation:Humans
  130. Holdsworth CH, Badawi RD, Santos P, Van den Abbeele AD, Hoffman EJ, and El Fakhri G. Evaluation of Three Monte Carlo and Model Based Scatter Correction Implementations in Clinical 3D PET. IEEE Trans Nucl Sci. 2006; in press.
  131. El Fakhri G., Guérin B., Sitek A., Di Carli M.F. Reproducibility of myocardial blood flow quantitation using Rb-82 and generalized factor and compartment analyses. J. Nucl. Med. 2006; 47.
  132. El Fakhri G., Surti S., Zimmerman R.E., de Vried D.J., Badawi R.D., Moore S.C. NEC and lesion detection in whole body PET. J. Nucl. Med. 2006; 47.
  133. El Fakhri G., Mahmood A., Ouyang J., Moore S.C., Limpa-Amara N., Zimmerman R.E. Simultaneous dual isotope micro-SPECT in the small animal. J. Nucl. Med. 2006; 47.
  134. Moore S.C. and El Fakhri G. Principles of Quantitation in Cardiac PET. Cardiac PET and PET/CT. 2006; in press.
  135. El Fakhri G. and Sitek A. Generalized 5D Spectral and Dynamic Factor Analysis. 2006.
  136. Ouyang J, El Fakhri G, Xia W, Kijewski MF, Genna S. The Design and Manufacture of an Annular Variable-focusing Collimator for High-sensitivity Brain SPECT. IEEE Trans Nucl Sci. 2006; in press.
  137. Moore SC, Ouyang J, Park M, El Fakhri G. Monte Carlo-based compensation for patient scatter, detector scatter, and crosstalk contamination in In-111 SPECT imaging. Nucl. Instrum. Meth. A. 2006; in press.
  138. Moore SC, Foley Kijewski M, El Fakhri G. Collimator optimization for detection and quantitation tasks: application to gallium-67 imaging. IEEE Trans Med Imaging. 2005 Oct; 24(10):1347-56. PMID: 16229420.
    Citations: 8     Fields:    Translation:Humans
  139. El Fakhri G, Habert MO, Maksud P, Kas A, Malek Z, Kijewski MF, Lacomblez L. Quantitative simultaneous (99m)Tc-ECD/123I-FP-CIT SPECT in Parkinson's disease and multiple system atrophy. Eur J Nucl Med Mol Imaging. 2006 Jan; 33(1):87-92. PMID: 16180033.
    Citations: 13     Fields:    Translation:Humans
  140. El Fakhri G, Sitek A, Guérin B, Kijewski MF, Di Carli MF, Moore SC. Quantitative dynamic cardiac 82Rb PET using generalized factor and compartment analyses. J Nucl Med. 2005 Aug; 46(8):1264-71. PMID: 16085581.
    Citations: 48     Fields:    Translation:HumansCTClinical Trials
  141. El Fakhri G. and Sitek A. Fast, Unique, and Robust Factor Analysis. 2005.
  142. Moore SC, Park MA, Kijewski MF, El Fakhri G, Mueller SP. Improved estimation of PET SUV using CT-based model fitting within small image volumes. J. Nucl. Med. 2005; 46:107.
  143. Ouyang J, Moore SC, Park M, El Fakhri G. Monte Carlo estimation of patient and detector scatter and crosstalk contamination in SPECT imaging. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2005; CD-ROM.
  144. Kijewski MF, El Fakhri G, Mueller SP, Moore SC. Maximum-likelihood estimation of dual-tracer striatal activity concentration from simultaneously acquired SPECT data. J. Nucl. Med. 2005; 46:105.
  145. Guérin B, El Fakhri G. Monte Carlo simulation of randoms and pixellated block detectors : Validation using the NEMA NU-2 test procedures. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2005; CD-ROM.
  146. Habert MO, Kas A, Maksud P, Malek Z, El Fakhri G, Lacomblez . Role of coupled brain perfusion and dopamine transporter imaging in the diagnosis of cortico-basal degeneration: a double isotope study. Eur J Nucl Med Mol Imag. 2005; 32:208.
  147. El Fakhri G, Sitek A, Ouyang J, Zimmerman RE. Generalized 5D dynamic and spectral factor analysis. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2005; CD-ROM.
  148. El Fakhri G, Kijewski MF, Albert MS, Johnson KA, Moore SC. Quantitative SPECT leads to improved performance in discrimination tasks related to prodromal Alzheimer's disease. J Nucl Med. 2004 Dec; 45(12):2026-31. PMID: 15585477.
    Citations: 5     Fields:    Translation:Humans
  149. El Fakhri G, Sitek A, Di Carli MF, Kijewski MF, Moore SC. Quantitative Dynamic Cardiac 82Rb-PET Imaging. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2004; CD-ROM.
  150. Sitek A, El Fakhri G. A Novel Solution to the Uniqueness problem in Factor Analysis of Dynamic Sequences. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2004; CD-ROM.
  151. El Fakhri G, Habert MO, Shlossberg E, Albert MS, and Kijewski MF. Identification of SPECT abnormalities in prodromal Alzheimer disease using a voxel based approach. J. Nucl. Med. 2004; 45:11.
  152. El Fakhri G., Sitek A., Di Carli M.F., Moore S.C. Quantitative Dynamic Cardiac Rb-82 imaging using Penalized Least Squares Factor Analysis of Dynamic Sequences. Eur. J. Nucl. Med. Mol. Imag. 2004; 31:289.
  153. Kinahan, P.E., Surti S., Badawi R.D., El Fakhri G., Karp J.S., Lewellen T.K. Effect of patient thickness on noise equivalent count rates for 2D and fully 3D whole body PET imaging. J. Nucl. Med. 2004; 45:102.
  154. El Fakhri G., Habert M.O., Lacomblez L., Kijewski M.F., Maksud P. Quantitative simultaneous Tc-99m ECD/I-123 FP-CIT SPECT in Parkinson disease and multiple system atrophy. J. Nucl. Med. 2004; 45:71.
  155. Moore S.C., Park M., El Fakhri G., Gerbaudo V., Zimmerman R.E. A general-spectral method for improved quantitative SPECT imaging of In-111. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2004; CD-ROM.
  156. El Fakhri G, Kijewski MF, Johnson KA, Syrkin G, Killiany RJ, Becker JA, Zimmerman RE, Albert MS. MRI-guided SPECT perfusion measures and volumetric MRI in prodromal Alzheimer disease. Arch Neurol. 2003 Aug; 60(8):1066-72. PMID: 12925361.
    Citations: 17     Fields:    Translation:Humans
  157. El Fakhri G, Zimmerman RE, Moore SC, Maksud P, Fischman AJ. Quantitative 99mTc/123I in pre-/post-synaptic and cardiac SPECT. Eur J Nucl Med Mol Imag. 2003; 30:321.
  158. El Fakhri G, Moore SC, Maksud P, and Kijewski MF. The effects of compensation for scatter, lead x-rays and high-energy contamination on lesion detectability and activity estimation in Ga-67 imaging. IEEE Trans Nucl Sci. 2003; 50:439-445.
  159. El Fakhri G, Albert MS, Johnson KA, Syrkin G, Moore SC, Zimmerman RE, Killiany RJ, Kijewski MF. Impact of brain attenuation map and reconstruction algorithm on discrimination performance in prodromal Alzheimer’s disease. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2003; CD-ROM.
  160. Surti S, Badawi RD, Holdsworth H, El Fakhri G, Kinahan P, Karp JS. A multi-scanner evaluation of PET image quality using phantom studies. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2003; CD-ROM.
  161. Holdsworth H, Badawi RD, Santos PA, Van den Abbeele AD, El Fakhri G. Evaluation of a Monte Carlo scatter correction in clinical 3D PET. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2003; CD-ROM.
  162. El Fakhri G, Holdsworth H, Badawi RD, Santos PA, Kijewski MF, Van den Abbeele AD, Moore SC. Dependence of Whole-Body-FDG-PET lesion detection and activity estimation performance on patient size, randoms variance reduction and acquisition geometry. J. Nucl. Med. 2003; 44:197.
  163. Moore SC and El Fakhri G. Performance of a joint, multiple-energy iterative SPECT reconstruction algorithm in tumor activity estimation. J. Nucl. Med. 2003; 44:210.
  164. Kijewski MF, El Fakhri G, Moore SC. Performance of simultaneous and sequential Tc-99m/I-123 SPECT imaging in estimation of striatal activity. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2003; CD-ROM.
  165. Moore SC, El Fakhri G, Park MA, Kijewski MF. Quantitative Ga-67 SPECT imaging. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2003; CD-ROM.
  166. El Fakhri G, Holdsworth H, Santos PA, Badawi RD, Van den Abbeele AD and Kijewski MF. Impact of patient size, acquisition mode, reconstruction algorithm, and randoms and attenuation corrections on lesion detection and activity estimation in whole-body FDG-PET. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2003; CD-ROM.
  167. Badawi RD, Surti S, Kemp B, El Fakhri G, Worstell WA, Zimmerman RE. The effects of pulse pile-up on point source measurements performed on different PET scanning devices. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2003; CD-ROM.
  168. El Fakhri G, Moore SC, Kijewski MF. Optimization of Ga-67 imaging for detection and estimation tasks: dependence of imaging performance on spectral acquisition parameters. Med Phys. 2002 Aug; 29(8):1859-66. PMID: 12201433.
    Citations: 2     Fields:    Translation:Humans
  169. Habert M.O., Lacomblez L., Maksud P., Pradat P.F., El Fakhri G., Aurengo A., Meininger V. Brain perfusion imaging in amyotrophic lateral sclerosis: relationships with severity of motor impairment. J. Nucl. Med. 2002; 43:244.
  170. El Fakhri G., Maksud P., Kijewski M.F., Zimmerman RE, Moore SC. Quantitative simultaneous Tc-99m/I-123 SPECT: design study and validation with Monte Carlo simulations and physical acquisitions. IEEE Trans Nucl Sci. 2002; 49:2315-2321.
  171. Moore SC, Santos P.A., Holdsworth C.H., El Fakhri G. Acceleration of SPECT Monte Carlo simulation using delta scattering. J. Nucl. Med. 2002; 43:53.
  172. G. El Fakhri, M. F. Kijewski, G. Syrkin, K.A. Johnson, M. S. Albert and S. C. Moore. Comparison of reconstruction and correction algorithms based on performance in diagnosis of preclinical Alzheimer’s disease. J. Nucl. Med. 2002; 43:215.
  173. El Fakhri G., Holdsworth H, Badawi RD, Santos PA, Moore SC, Van den Abbeele AD and Kijewski MF. Impact of acquisition geometry and patient habitus on tumor detectability in whole-body FDG-PET: a channelized Hotelling observer study. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2002; CD-ROM.
  174. Moore SC, El Fakhri G., and Kijewski MF. Optimal Parallel-Hole Collimation for Lesion Detection and Activity Estimation in Ga-67 Imaging. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2002; CD-ROM.
  175. Kijewski MF, El Fakhri G., Fischman AJ, Mueller SP, and Moore SC. The effects of resolution recovery on estimation of binding potential from brain SPECT images. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2002; CD-ROM.
  176. El Fakhri G., Moore SC, Maksud P., and Kijewski MF. The effects of compensation for scatter, lead x-rays and high-energy contamination on lesion detectability and activity estimation in Ga-67 imaging. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2002; CD-ROM.
  177. El Fakhri G, Moore SC, Maksud P, Aurengo A, Kijewski MF. Absolute activity quantitation in simultaneous 123I/99mTc brain SPECT. J Nucl Med. 2001 Feb; 42(2):300-8. PMID: 11216530.
    Citations: 14     Fields:    Translation:Humans
  178. Moore S.C., El Fakhri G., Maksud P. Comparative assessment of energy-based methods of compensating for scatter and lead x-rays in Ga-67 SPECT imaging. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2001; CD-ROM.
  179. El Fakhri G., Moore S.C., and Kijewski M.F. Optimization of Ga-67 imaging for detection and estimation tasks: dependence of imaging performance on choice of energy windows. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2001; CD-ROM.
  180. Moore SC and El Fakhri G. Realistic Monte Carlo simulation of Ga-67 SPECT imaging. IEEE Trans Nucl Sci. 2001; 48:720-724.
  181. El Fakhri G, Moore SC, Maksud P, Aurengo A, Kijewski MF. Absolute activity quantitation in simultaneous I-123/Tc-99m brain SPECT. IEEE Trans Nucl Sci. 2001; 48:799-804.
  182. El Fakhri G., Maksud P., Moore S.C., Zimmerman R.E., and Kijewski M.F. Absolute quantitation in simultaneous Tc-99m/I-123 brain SPECT using ANN: design optimization and validation. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2001; CD-ROM.
  183. El Fakhri G, Kijewski MF, Moore SC. Absolute activity quantitation from projections using an analytical approach: comparison with iterative methods in brain SPECT. IEEE Trans Nucl Sci. 2001; 48:768-773.
  184. El Fakhri G, Buvat I, Almeida P, Bendriem B, Todd-Pokropek A, Benali H. Should scatter be corrected in both transmission and emission data for accurate quantitation in cardiac SPET? Eur J Nucl Med. 2000 Sep; 27(9):1356-64. PMID: 11007518.
    Citations:    Fields:    Translation:Humans
  185. El Fakhri G, Buvat I, Benali H, Todd-Pokropek A, Di Paola R. Relative impact of scatter, collimator response, attenuation, and finite spatial resolution corrections in cardiac SPECT. J Nucl Med. 2000 Aug; 41(8):1400-8. PMID: 10945534.
    Citations: 13     Fields:    Translation:Humans
  186. El Fakhri G., Kijewski M.F., and Moore S.C. Absolute activity quantitation from projections using an analytical approach: comparison with iterative methods in brain SPECT. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2000; CD-ROM.
  187. El Fakhri G, Maksud P, Kijewski MF, Habert MO, Todd-Pokropek A, Aurengo A, Moore SC. Scatter and Cross-Talk Corrections in Simultaneous Tc-99m/I-123 Brain SPECT using Constrained Factor Analysis and Artificial Neural Networks. IEEE Trans Nucl Sci. 2000; 47:1573-1580.
  188. El Fakhri G., Moore S.C., and Maksud P. A new scatter compensation method for Ga-67 imaging using artificial neural networks. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2000; CD-ROM.
  189. Moore SC, El Fakhri G., Badawi RD, Van den Abbeele AD, Zimmerman RE. Relative lesion detectability in 3D vs. 2D dedicated multi-ring PET. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 2000; CD-ROM.
  190. Pélégrini M, Buvat I, Benali H, El Fakhri G, Grangeat P, Di Paola R. A spline-regularized minimal residual algorithm for iterative attenuation correction in SPECT. Phys Med Biol. 1999 Oct; 44(10):2623-42. PMID: 10533932.
    Citations:    Fields:    Translation:Humans
  191. el Fakhri GN, Buvat I, Pélégrini M, Benali H, Almeida P, Bendriem B, Todd-Pokropek A, Di Paola R. Respective roles of scatter, attenuation, depth-dependent collimator response and finite spatial resolution in cardiac single-photon emission tomography quantitation: a Monte Carlo study. Eur J Nucl Med. 1999 May; 26(5):437-46. PMID: 10382086.
    Citations: 7     Fields:    Translation:Humans
  192. Buvat I, El Fakhri G., Pélégrini M, Benali H, Todd-Pokropek A, Di Paola R. Relative impact of the different physical corrections in SPECT. A. Co. Med. Nuc. 1999; 5:169-179.
  193. Buvat I, Chameroy V, Aubry F, Pelegrini M, El Fakhri G, Huguenin C, Benali H, Todd-Pokropek A, Di Paola R. The need to develop guidelines for the evaluation of medical image processing procedures. SPIE. 1999; 3661:1466-1477.
  194. El Fakhri G., Moore S.C., Kijewski M.F., Maksud P, Todd-Pokropek A. Monte Carlo evaluation of quantitation in simultaneous Tc-99m/I-123 brain SPECT using constrained spectral factor analysis. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 1999; CD-ROM.
  195. El Fakhri G., Buvat I, Pélégrini M, Benali H, Almeida P, Bendriem B, Todd-Pokropek A, Di Paola R. . Respective roles of scatter, attenuation, collimator response and partial volume effect in cardiac SPECT quantitation: a Monte Carlo study. Eur. J. Nucl. Med. 1999; 26:437-446.
  196. El Fakhri G., Maksud P, Habert M.O, Todd-Pokropek A, Aurengo A. A new correction method for cross-talk using artificial neural networks: validation in simultaneous technetium and iodine cerebral imaging. Proc. IEEE Nucl. Sci. Symp. & Med. Imag. Conf. 1999; CD-ROM.
  197. El Fakhri G. Development of an evaluation system for quantitation in SPECT. 1998.
  198. Maksud P, Fertil B, Rica C, El Fakhri G, Aurengo A. Artificial neural network as a tool to compensate for scatter and attenuation in radionuclide imaging. J Nucl Med. 1998 Apr; 39(4):735-45. PMID: 9544691.
    Citations: 4     Fields:    Translation:Humans
  199. Pélégrini M, Benali H, Buvat I, el Fakhri G, Di Paola R. Two-dimensional statistical model for regularized backprojection in SPECT. Phys Med Biol. 1998 Feb; 43(2):421-34. PMID: 9509536.
    Citations:    Fields:    Translation:Humans
  200. Buvat I, El Fakhri G., Pélégrini M, Benali H, Di Paola R. . Effects of Compton scattering and simple scatter correction methods in SPECT. A. Co. Med. Nuc. 1998; 2:130-140.
  201. Buvat I, El Fakhri G., Pélégrini M, Benali H, Di Paola R. . Comparison of different protocols for attenuation correction in cardiac imaging. A. Co. Med. Nuc. 1998; 2:121-129.
  202. Koulibaby PM, Buvat I, Pélégrini M, El Fakhri G. Correction for variable spatial resolution due to collimator response. A. Co. Med. Nuc. 1998; 2:114-120.
  203. El Fakhri G., Maksud P, Aurengo A. . Evaluation of scatter correction methods using Monte Carlo simulation in non uniform media. SPIE. 1998; 3338:363-370.
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.