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profileEric Allen Macklin, Ph.D.

TitleInstructor in Medicine
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
MGH Biostatistics, Ste 560
50 Staniford Street
Boston MA 02114
Phone617/724-9828
Fax617/724-9878
vCardDownload vCard (login for email)

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U01AT000210     (MACKLIN, ERIC A)Jun 1, 2000 - Nov 30, 2004
NIH/NCCIH
CLINICAL TRIAL OF ACUPUNCTURE FOR TREATING HYPERTENSION
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Jayaratne YSN, Elsharkawi I, Macklin EA, Voelz L, Weintraub G, Rosen D, Skotko BG. The facial morphology in Down syndrome: A 3D comparison of patients with and without obstructive sleep apnea. Am J Med Genet A. 2017 Aug 17. PMID: 28815893.
    View in: PubMed
  2. Wayne PM, Gagnon MM, Macklin EA, Travison TG, Manor B, Lachman M, Thomas CP, Lipsitz LA. The Mind Body-Wellness in Supportive Housing (Mi-WiSH) study: Design and rationale of a cluster randomized controlled trial of Tai Chi in senior housing. Contemp Clin Trials. 2017 Sep; 60:96-104. PMID: 28694204.
    View in: PubMed
  3. Kuhlthau KA, McDonnell E, Coury DL, Payakachat N, Macklin E. Associations of quality of life with health-related characteristics among children with autism. Autism. 2017 Jul 01; 1362361317704420. PMID: 28691502.
    View in: PubMed
  4. Smith R, Pioro E, Myers K, Sirdofsky M, Goslin K, Meekins G, Yu H, Wymer J, Cudkowicz M, Macklin EA, Schoenfeld D, Pattee G. Enhanced Bulbar Function in Amyotrophic Lateral Sclerosis: The Nuedexta Treatment Trial. Neurotherapeutics. 2017 Jul; 14(3):762-772. PMID: 28070747.
    View in: PubMed
  5. Smith R, Pioro E, Myers K, Sirdofsky M, Goslin K, Meekins G, Yu H, Wymer J, Cudkowicz M, Macklin EA, Schoenfeld D, Pattee G. Erratum to: Enhanced Bulbar Function in Amyotrophic Lateral Sclerosis: The Nuedexta Treatment Trial. Neurotherapeutics. 2017 Jul; 14(3):830. PMID: 28283968.
    View in: PubMed
  6. Berry JD, Paganoni S, Atassi N, Macklin EA, Goyal N, Rivner M, Simpson E, Appel S, Grasso DL, Mejia NI, Mateen F, Gill A, Vieira F, Tassinari V, Perrin S. Phase IIa trial of fingolimod for amyotrophic lateral sclerosis demonstrates acceptable acute safety and tolerability. Muscle Nerve. 2017 Jun 29. PMID: 28662296.
    View in: PubMed
  7. Mazurek MO, Lu F, Symecko H, Butter E, Bing NM, Hundley RJ, Poulsen M, Kanne SM, Macklin EA, Handen BL. A Prospective Study of the Concordance of DSM-IV and DSM-5 Diagnostic Criteria for Autism Spectrum Disorder. J Autism Dev Disord. 2017 Jun 16. PMID: 28620892.
    View in: PubMed
  8. Marler S, Ferguson BJ, Lee EB, Peters B, Williams KC, McDonnell E, Macklin EA, Levitt P, Margolis KG, Beversdorf DQ, Veenstra-VanderWeele J. Association of Rigid-Compulsive Behavior with Functional Constipation in Autism Spectrum Disorder. J Autism Dev Disord. 2017 Jun; 47(6):1673-1681. PMID: 28289979.
    View in: PubMed
  9. Song R, Grabowska W, Park M, Osypiuk K, Vergara-Diaz GP, Bonato P, Hausdorff JM, Fox M, Sudarsky LR, Macklin E, Wayne PM. The impact of Tai Chi and Qigong mind-body exercises on motor and non-motor function and quality of life in Parkinson's disease: A systematic review and meta-analysis. Parkinsonism Relat Disord. 2017 Aug; 41:3-13. PMID: 28602515.
    View in: PubMed
  10. Elsharkawi I, Gozal D, Macklin EA, Voelz L, Weintraub G, Skotko BG. Urinary biomarkers and obstructive sleep apnea in patients with Down syndrome. Sleep Med. 2017 Jun; 34:84-89. PMID: 28522103.
    View in: PubMed
  11. Espay AJ, Schwarzschild MA, Tanner CM, Fernandez HH, Simon DK, Leverenz JB, Merola A, Chen-Plotkin A, Brundin P, Kauffman MA, Erro R, Kieburtz K, Woo D, Macklin EA, Standaert DG, Lang AE. Biomarker-driven phenotyping in Parkinson's disease: A translational missing link in disease-modifying clinical trials. Mov Disord. 2017 Mar; 32(3):319-324. PMID: 28233927.
    View in: PubMed
  12. Kuo B, Bhasin M, Jacquart J, Scult MA, Slipp L, Riklin EI, Lepoutre V, Comosa N, Norton BA, Dassatti A, Rosenblum J, Thurler AH, Surjanhata BC, Hasheminejad NN, Kagan L, Slawsby E, Rao SR, Macklin EA, Fricchione GL, Benson H, Libermann TA, Korzenik J, Denninger JW. Correction: Genomic and Clinical Effects Associated with a Relaxation Response Mind-Body Intervention in Patients with Irritable Bowel Syndrome and Inflammatory Bowel Disease. PLoS One. 2017; 12(2):e0172872. PMID: 28222181.
    View in: PubMed
  13. Skotko BG, Macklin EA, Muselli M, Voelz L, McDonough ME, Davidson E, Allareddy V, Jayaratne YS, Bruun R, Ching N, Weintraub G, Gozal D, Rosen D. A predictive model for obstructive sleep apnea and Down syndrome. Am J Med Genet A. 2017 Apr; 173(4):889-896. PMID: 28124477.
    View in: PubMed
  14. Andres PL, Allred MP, Stephens HE, Proffitt Bunnell M, Siener C, Macklin EA, Haines T, English RA, Fetterman KA, Kasarskis EJ, Florence J, Simmons Z, Cudkowicz ME. Fixed dynamometry is more sensitive than vital capacity or ALS rating scale. Muscle Nerve. 2017 Jan 24. PMID: 28120413.
    View in: PubMed
  15. Neumeyer AM, Cano Sokoloff N, McDonnell E, Macklin EA, McDougle CJ, Misra M. Bone microarchitecture in adolescent boys with autism spectrum disorder. Bone. 2017 Apr; 97:139-146. PMID: 28088646.
    View in: PubMed
  16. Paganoni S, Macklin EA, Karam C, Yu H, Gonterman F, Fetterman KA, Cudkowicz M, Berry J, Wills AM. Vitamin D levels are associated with gross motor function in amyotrophic lateral sclerosis. Muscle Nerve. 2017 Jan 03. PMID: 28044349.
    View in: PubMed
  17. Neumeyer AM, Cano Sokoloff N, McDonnell E, Macklin EA, McDougle CJ, Misra M. Bone Accrual in Males with Autism Spectrum Disorder. J Pediatr. 2017 Feb; 181:195-201.e6. PMID: 27887681.
    View in: PubMed
  18. Allareddy V, Ching N, Macklin EA, Voelz L, Weintraub G, Davidson E, Prock LA, Rosen D, Brunn R, Skotko BG. Craniofacial features as assessed by lateral cephalometric measurements in children with Down syndrome. Prog Orthod. 2016 Dec; 17(1):35. PMID: 27722998.
    View in: PubMed
  19. Wertheim BM, Aguirre AJ, Bhattacharyya RP, Chorba J, Jadhav AP, Kerry VB, Macklin EA, Motyckova G, Raju S, Lewandrowski K, Hunt DP, Wright DE. An Educational and Administrative Intervention to Promote Rational Laboratory Test Ordering on an Academic General Medicine Service. Am J Med. 2017 Jan; 130(1):47-53. PMID: 27619354.
    View in: PubMed
  20. Anagnostou E, Aman MG, Handen BL, Sanders KB, Shui A, Hollway JA, Brian J, Arnold LE, Capano L, Hellings JA, Butter E, Mankad D, Tumuluru R, Kettel J, Newsom CR, Hadjiyannakis S, Peleg N, Odrobina D, McAuliffe-Bellin S, Zakroysky P, Marler S, Wagner A, Wong T, Macklin EA, Veenstra-VanderWeele J. Metformin for Treatment of Overweight Induced by Atypical Antipsychotic Medication in Young People With Autism Spectrum Disorder: A Randomized Clinical Trial. JAMA Psychiatry. 2016 Sep 01; 73(9):928-37. PMID: 27556593.
    View in: PubMed
  21. Lu W, Wayne PM, Davis RB, Buring JE, Li H, Macklin EA, Lorch JH, Burke E, Haddad TC, Goguen LA, Rosenthal DS, Tishler RB, Posner MR, Haddad RI. Acupuncture for Chemoradiation Therapy-Related Dysphagia in Head and Neck Cancer: A Pilot Randomized Sham-Controlled Trial. Oncologist. 2016 Dec; 21(12):1522-1529. PMID: 27511906.
    View in: PubMed
  22. Vranceanu AM, Riklin E, Merker VL, Macklin EA, Park ER, Plotkin SR. Mind-body therapy via videoconferencing in patients with neurofibromatosis: An RCT. Neurology. 2016 Aug 23; 87(8):806-14. PMID: 27449066.
    View in: PubMed
  23. Ferguson BJ, Marler S, Altstein LL, Lee EB, Akers J, Sohl K, McLaughlin A, Hartnett K, Kille B, Mazurek M, Macklin EA, McDonnell E, Barstow M, Bauman ML, Margolis KG, Veenstra-VanderWeele J, Beversdorf DQ. Psychophysiological Associations with Gastrointestinal Symptomatology in Autism Spectrum Disorder. Autism Res. 2017 Feb; 10(2):276-288. PMID: 27321113.
    View in: PubMed
  24. Tran K, Staller K, Macklin E, Goldstein A, Belkind-Gerson J, Kuo B. Need for Rectal Biopsy for Childhood Constipation Predicts Severity of Illness and Need for Laxatives. J Pediatr Gastroenterol Nutr. 2016 Jun; 62(6):834-9. PMID: 26551318.
    View in: PubMed
  25. Malow BA, Connolly HV, Weiss SK, Halbower A, Goldman S, Hyman SL, Katz T, Madduri N, Shui A, Macklin E, Reynolds AM. The Pediatric Sleep Clinical Global Impressions Scale-A New Tool to Measure Pediatric Insomnia in Autism Spectrum Disorders. J Dev Behav Pediatr. 2016 Jun; 37(5):370-6. PMID: 27244298.
    View in: PubMed
  26. Ferguson BJ, Marler S, Altstein LL, Lee EB, Mazurek MO, McLaughlin A, Macklin EA, McDonnell E, Davis DJ, Belenchia AM, Gillespie CH, Peterson CA, Bauman ML, Margolis KG, Veenstra-VanderWeele J, Beversdorf DQ. Associations between cytokines, endocrine stress response, and gastrointestinal symptoms in autism spectrum disorder. Brain Behav Immun. 2016 Nov; 58:57-62. PMID: 27181180.
    View in: PubMed
  27. Gandhi RT, Kwon DS, Macklin EA, Shopis JR, McLean AP, McBrine N, Flynn T, Peter L, Sbrolla A, Kaufmann DE, Porichis F, Walker BD, Bhardwaj N, Barouch DH, Kavanagh DG. Immunization of HIV-1-Infected Persons With Autologous Dendritic Cells Transfected With mRNA Encoding HIV-1 Gag and Nef: Results of a Randomized, Placebo-Controlled Clinical Trial. J Acquir Immune Defic Syndr. 2016 Mar 01; 71(3):246-53. PMID: 26379068; PMCID: PMC4752409.
  28. Marler S, Ferguson BJ, Lee EB, Peters B, Williams KC, McDonnell E, Macklin EA, Levitt P, Gillespie CH, Anderson GM, Margolis KG, Beversdorf DQ, Veenstra-VanderWeele J. Brief Report: Whole Blood Serotonin Levels and Gastrointestinal Symptoms in Autism Spectrum Disorder. J Autism Dev Disord. 2016 Mar; 46(3):1124-30. PMID: 26527110; PMCID: PMC4852703.
  29. Weiss MD, Macklin EA, Simmons Z, Knox AS, Greenblatt DJ, Atassi N, Graves M, Parziale N, Salameh JS, Quinn C, Brown RH, Distad JB, Trivedi J, Shefner JM, Barohn RJ, Pestronk A, Swenson A, Cudkowicz ME. A randomized trial of mexiletine in ALS: Safety and effects on muscle cramps and progression. Neurology. 2016 Apr 19; 86(16):1474-81. PMID: 26911633; PMCID: PMC4836879 [Available on 04/19/17].
  30. Bhattacharyya S, Bakshi R, Logan R, Ascherio A, Macklin EA, Schwarzschild MA. Oral Inosine Persistently Elevates Plasma antioxidant capacity in Parkinson's disease. Mov Disord. 2016 Mar; 31(3):417-21. PMID: 26805433.
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  31. Deshmukh U, Adams J, Macklin EA, Dhillon R, McCarthy KD, Dworetzky B, Klein A, Holmes LB. Behavioral outcomes in children exposed prenatally to lamotrigine, valproate, or carbamazepine. Neurotoxicol Teratol. 2016 Mar-Apr; 54:5-14. PMID: 26791321.
    View in: PubMed
  32. Skotko BG, Levine SP, Macklin EA, Goldstein RD. Family perspectives about Down syndrome. Am J Med Genet A. 2016 Apr; 170A(4):930-41. PMID: 26692378.
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  33. Bedlack RS, Vaughan T, Wicks P, Heywood J, Sinani E, Selsov R, Macklin EA, Schoenfeld D, Cudkowicz M, Sherman A. How common are ALS plateaus and reversals? Neurology. 2016 Mar 01; 86(9):808-12. PMID: 26658909; PMCID: PMC4793781.
  34. van Veluw SJ, Biessels GJ, Bouvy WH, Spliet WG, Zwanenburg JJ, Luijten PR, Macklin EA, Rozemuller AJ, Gurol ME, Greenberg SM, Viswanathan A, Martinez-Ramirez S. Cerebral amyloid angiopathy severity is linked to dilation of juxtacortical perivascular spaces. J Cereb Blood Flow Metab. 2016 Mar; 36(3):576-80. PMID: 26661250; PMCID: PMC4794108 [Available on 03/01/17].
  35. Viswanathan A, Macklin EA, Betensky R, Hyman B, Smith EE, Blacker D. The Influence of Vascular Risk Factors and Stroke on Cognition in Late Life: Analysis of the NACC Cohort. Alzheimer Dis Assoc Disord. 2015 Oct-Dec; 29(4):287-93. PMID: 25626633; PMCID: PMC4514567 [Available on 10/01/16].
  36. Kassim AA, Payne AB, Rodeghier M, Macklin EA, Strunk RC, DeBaun MR. Low forced expiratory volume is associated with earlier death in sickle cell anemia. Blood. 2015 Sep 24; 126(13):1544-50. PMID: 26261241; PMCID: PMC4582330 [Available on 09/24/16].
  37. Walsh JN, Manor B, Hausdorff J, Novak V, Lipsitz L, Gow B, Macklin EA, Peng CK, Wayne PM. Impact of Short- and Long-term Tai Chi Mind-Body Exercise Training on Cognitive Function in Healthy Adults: Results From a Hybrid Observational Study and Randomized Trial. Glob Adv Health Med. 2015 Jul; 4(4):38-48. PMID: 26331103; PMCID: PMC4533658.
  38. Martinez-Ramirez S, Romero JR, Shoamanesh A, McKee AC, Van Etten E, Pontes-Neto O, Macklin EA, Ayres A, Auriel E, Himali JJ, Beiser AS, DeCarli C, Stein TD, Alvarez VE, Frosch MP, Rosand J, Greenberg SM, Gurol ME, Seshadri S, Viswanathan A. Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage. Alzheimers Dement. 2015 Dec; 11(12):1480-1488. PMID: 26079413; PMCID: PMC4677060 [Available on 12/01/16].
  39. Wayne PM, Hausdorff JM, Lough M, Gow BJ, Lipsitz L, Novak V, Macklin EA, Peng CK, Manor B. Tai Chi Training may Reduce Dual Task Gait Variability, a Potential Mediator of Fall Risk, in Healthy Older Adults: Cross-Sectional and Randomized Trial Studies. Front Hum Neurosci. 2015; 9:332. PMID: 26106316; PMCID: PMC4460804.
  40. Stewart PA, Hyman SL, Schmidt BL, Macklin EA, Reynolds A, Johnson CR, James SJ, Manning-Courtney P. Dietary Supplementation in Children with Autism Spectrum Disorders: Common, Insufficient, and Excessive. J Acad Nutr Diet. 2015 Aug; 115(8):1237-48. PMID: 26052041.
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  41. de Vinck-Baroody O, Shui A, Macklin EA, Hyman SL, Leventhal JM, Weitzman C. Overweight and Obesity in a Sample of Children With Autism Spectrum Disorder. Acad Pediatr. 2015 Jul-Aug; 15(4):396-404. PMID: 25937610.
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  42. Kuo B, Bhasin M, Jacquart J, Scult MA, Slipp L, Riklin EI, Lepoutre V, Comosa N, Norton BA, Dassatti A, Rosenblum J, Thurler AH, Surjanhata BC, Hasheminejad NN, Kagan L, Slawsby E, Rao SR, Macklin EA, Fricchione GL, Benson H, Libermann TA, Korzenik J, Denninger JW. Genomic and clinical effects associated with a relaxation response mind-body intervention in patients with irritable bowel syndrome and inflammatory bowel disease. PLoS One. 2015; 10(4):e0123861. PMID: 25927528; PMCID: PMC4415769.
  43. Phitayakorn R, Macklin EA, Goldsmith J, Weinstein DF. Applicants' Self-Reported Priorities in Selecting a Residency Program. J Grad Med Educ. 2015 Mar; 7(1):21-6. PMID: 26217417; PMCID: PMC4507921.
  44. Blumenthal DM, Singal G, Mangla SS, Macklin EA, Chung DC. Predicting Non-Adherence with Outpatient Colonoscopy Using a Novel Electronic Tool that Measures Prior Non-Adherence. J Gen Intern Med. 2015 Jun; 30(6):724-31. PMID: 25586869; PMCID: PMC4441666.
  45. Psaros C, Kagan L, Shifren JL, Willett J, Jacquart J, Alert MD, Macklin EA, Styer AK, Denninger JW, LaRoche KL, Park ER. Mind-body group treatment for women coping with infertility: a pilot study. J Psychosom Obstet Gynaecol. 2015; 36(2):75-83. PMID: 25541217.
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  46. Wayne PM, Gow BJ, Costa MD, Peng CK, Lipsitz LA, Hausdorff JM, Davis RB, Walsh JN, Lough M, Novak V, Yeh GY, Ahn AC, Macklin EA, Manor B. Complexity-Based Measures Inform Effects of Tai Chi Training on Standing Postural Control: Cross-Sectional and Randomized Trial Studies. PLoS One. 2014; 9(12):e114731. PMID: 25494333; PMCID: PMC4262457.
  47. Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW. Sulforaphane treatment of autism spectrum disorder (ASD). Proc Natl Acad Sci U S A. 2014 Oct 28; 111(43):15550-5. PMID: 25313065; PMCID: PMC4217462.
  48. Nasri HZ, Westgate MN, Macklin EA, Holmes LB. Vascular limb defects and maternal age. Birth Defects Res A Clin Mol Teratol. 2014 Oct; 100(10):760-3. PMID: 25181518.
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  49. Johnson CR, Turner K, Stewart PA, Schmidt B, Shui A, Macklin E, Reynolds A, James J, Johnson SL, Manning Courtney P, Hyman SL. Relationships between feeding problems, behavioral characteristics and nutritional quality in children with ASD. J Autism Dev Disord. 2014 Sep; 44(9):2175-84. PMID: 24664635.
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  50. Schwarzschild MA, Macklin EA, Ascherio A. Urate and neuroprotection trials. Lancet Neurol. 2014 Aug; 13(8):758. PMID: 25030508.
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  51. Paganoni S, Macklin EA, Lee A, Murphy A, Chang J, Zipf A, Cudkowicz M, Atassi N. Diagnostic timelines and delays in diagnosing amyotrophic lateral sclerosis (ALS). Amyotroph Lateral Scler Frontotemporal Degener. 2014 Sep; 15(5-6):453-6. PMID: 24981792; PMCID: PMC4433003.
  52. Denninger J, Jacquart J, Miller K, Radossi A, Haime V, Macklin E, Gilburd D, Oliver MN, Mehta D, Yeung A, Fricchione G, Benson H. The effectiveness of a community-based mind body group intervention for depression & anxiety: a pilot study. J Altern Complement Med. 2014 May; 20(5):A55. PMID: 24805641.
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  53. Wills AM, Hubbard J, Macklin EA, Glass J, Tandan R, Simpson EP, Brooks B, Gelinas D, Mitsumoto H, Mozaffar T, Hanes GP, Ladha SS, Heiman-Patterson T, Katz J, Lou JS, Mahoney K, Grasso D, Lawson R, Yu H, Cudkowicz M. Hypercaloric enteral nutrition in patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled phase 2 trial. Lancet. 2014 Jun 14; 383(9934):2065-2072. PMID: 24582471; PMCID: PMC4176708.
  54. Schwarzschild MA, Ascherio A, Beal MF, Cudkowicz ME, Curhan GC, Hare JM, Hooper DC, Kieburtz KD, Macklin EA, Oakes D, Rudolph A, Shoulson I, Tennis MK, Espay AJ, Gartner M, Hung A, Bwala G, Lenehan R, Encarnacion E, Ainslie M, Castillo R, Togasaki D, Barles G, Friedman JH, Niles L, Carter JH, Murray M, Goetz CG, Jaglin J, Ahmed A, Russell DS, Cotto C, Goudreau JL, Russell D, Parashos SA, Ede P, Saint-Hilaire MH, Thomas CA, James R, Stacy MA, Johnson J, Gauger L, Antonelle de Marcaida J, Thurlow S, Isaacson SH, Carvajal L, Rao J, Cook M, Hope-Porche C, McClurg L, Grasso DL, Logan R, Orme C, Ross T, Brocht AF, Constantinescu R, Sharma S, Venuto C, Weber J, Eaton K. Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial. JAMA Neurol. 2014 Feb; 71(2):141-50. PMID: 24366103; PMCID: PMC3940333.
  55. Jacquart J, Miller KM, Radossi A, Haime V, Macklin E, Gilburd D, Nelson Oliver M, Mehta DH, Yeung A, Fricchione GL, Benson H, Denninger JW. The effectiveness of a community-based, mind-body group for symptoms of depression and anxiety. Adv Mind Body Med. 2014; 28(3):6-13. PMID: 25141353.
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  56. Stefanescu A, Macklin EA, Lin E, Dudzinski DM, Johnson J, Kennedy KF, Jacoby D, DeFaria Yeh D, Lewis GD, Yeh RW, Liberthson R, Lui G, Bhatt AB. Usefulness of the Seattle Heart Failure Model to identify adults with congenital heart disease at high risk of poor outcome. Am J Cardiol. 2014 Mar 01; 113(5):865-70. PMID: 24411285.
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  57. Atassi N, Yerramilli-Rao P, Szymonifka J, Yu H, Kearney M, Grasso D, Deng J, Levine-Weinberg M, Shapiro J, Lee A, Joseph L, Macklin EA, Cudkowicz ME. Analysis of start-up, retention, and adherence in ALS clinical trials. Neurology. 2013 Oct 08; 81(15):1350-5. PMID: 24005339; PMCID: PMC3806927.
  58. Goff DC, McEvoy JP, Citrome L, Mech AW, Bustillo JR, Gil R, Buckley P, Manschreck TC, Achtyes ED, Macklin EA. High-dose oral ziprasidone versus conventional dosing in schizophrenia patients with residual symptoms: the ZEBRAS study. J Clin Psychopharmacol. 2013 Aug; 33(4):485-90. PMID: 23775057.
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  59. Corben AD, Abi-Raad R, Popa I, Teo CH, Macklin EA, Koerner FC, Taghian AG, Brachtel EF. Pathologic response and long-term follow-up in breast cancer patients treated with neoadjuvant chemotherapy: a comparison between classifications and their practical application. Arch Pathol Lab Med. 2013 Aug; 137(8):1074-82. PMID: 23899063.
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  60. Alert MD, Rastegar S, Foret M, Slipp L, Jacquart J, Macklin E, Baim M, Fricchione G, Benson H, Denninger J, Yeung A. The effectiveness of a comprehensive mind body weight loss intervention for overweight and obese adults: a pilot study. Complement Ther Med. 2013 Aug; 21(4):286-93. PMID: 23876558.
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  61. Cummings BM, Macklin EA, Yager PH, Sharma A, Noviski N. Potassium abnormalities in a pediatric intensive care unit: frequency and severity. J Intensive Care Med. 2014 Sep-Oct; 29(5):269-74. PMID: 23753253.
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  62. Porter JB, Wood J, Olivieri N, Vichinsky EP, Taher A, Neufeld E, Giardina P, Thompson A, Moore B, Evans P, Kim HY, Macklin EA, Trachtenberg F. Treatment of heart failure in adults with thalassemia major: response in patients randomised to deferoxamine with or without deferiprone. J Cardiovasc Magn Reson. 2013 May 20; 15:38. PMID: 23688265; PMCID: PMC3669105.
  63. Roffman JL, Lamberti JS, Achtyes E, Macklin EA, Galendez GC, Raeke LH, Silverstein NJ, Smoller JW, Hill M, Goff DC. Randomized multicenter investigation of folate plus vitamin B12 supplementation in schizophrenia. JAMA Psychiatry. 2013 May; 70(5):481-9. PMID: 23467813; PMCID: PMC4394629.
  64. Miller TM, Pestronk A, David W, Rothstein J, Simpson E, Appel SH, Andres PL, Mahoney K, Allred P, Alexander K, Ostrow LW, Schoenfeld D, Macklin EA, Norris DA, Manousakis G, Crisp M, Smith R, Bennett CF, Bishop KM, Cudkowicz ME. An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study. Lancet Neurol. 2013 May; 12(5):435-42. PMID: 23541756; PMCID: PMC3712285.
  65. Macklin EA, Blacker D, Hyman BT, Betensky RA. Improved design of prodromal Alzheimer's disease trials through cohort enrichment and surrogate endpoints. J Alzheimers Dis. 2013; 36(3):475-86. PMID: 23629586; PMCID: PMC3779898.
  66. Hill M, Crumlish N, Clarke M, Whitty P, Owens E, Renwick L, Browne S, Macklin EA, Kinsella A, Larkin C, Waddington JL, O'Callaghan E. Prospective relationship of duration of untreated psychosis to psychopathology and functional outcome over 12 years. Schizophr Res. 2012 Nov; 141(2-3):215-21. PMID: 23006501.
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  67. Göbel A, Macklin EA, Winkler S, Betensky RA, Klein C, Lohmann K, Simon DK. Genetic risk factors in Parkinson's disease: single gene effects and interactions of genotypes. J Neurol. 2012 Nov; 259(11):2503-5. PMID: 22878430; PMCID: PMC3670989.
  68. Deipolyi AR, Wu O, Macklin EA, Schaefer PW, Schwamm LH, Gilberto Gonzalez R, Copen WA. Reliability of cerebral blood volume maps as a substitute for diffusion-weighted imaging in acute ischemic stroke. J Magn Reson Imaging. 2012 Nov; 36(5):1083-7. PMID: 22761110; PMCID: PMC4110961.
  69. Pulliam SJ, Weinstein DF, Malhotra A, Macklin EA, Berkowitz LR. Baseline sleep dysfunction among matriculating interns. J Grad Med Educ. 2012 Jun; 4(2):202-8. PMID: 23730442; PMCID: PMC3399613.
  70. Lau T, Weinstein M, Wakamatsu M, Macklin EA, Pulliam S. Low back pain does not improve with surgical treatment of pelvic organ prolapse. Int Urogynecol J. 2013 Jan; 24(1):147-53. PMID: 22618206.
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  71. Roffman JL, Brohawn DG, Nitenson AZ, Macklin EA, Smoller JW, Goff DC. Genetic variation throughout the folate metabolic pathway influences negative symptom severity in schizophrenia. Schizophr Bull. 2013 Mar; 39(2):330-8. PMID: 22021659; PMCID: PMC3576161.
  72. Tinsley A, Macklin EA, Korzenik JR, Sands BE. Validation of the functional assessment of chronic illness therapy-fatigue (FACIT-F) in patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2011 Dec; 34(11-12):1328-36. PMID: 21999576.
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  73. Viswanathan AN, Macklin EA, Berkowitz R, Matulonis U. The importance of chemotherapy and radiation in uterine papillary serous carcinoma. Gynecol Oncol. 2011 Dec; 123(3):542-7. PMID: 21963091.
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  74. Gottlieb JD, Cather C, Shanahan M, Creedon T, Macklin EA, Goff DC. D-cycloserine facilitation of cognitive behavioral therapy for delusions in schizophrenia. Schizophr Res. 2011 Sep; 131(1-3):69-74. PMID: 21723096; PMCID: PMC3389827.
  75. Henderson DC, Freudenreich O, Borba CP, Wang X, Copeland PM, Macklin E, Fan X, Cather C, Goff DC. Effects of modafinil on weight, glucose and lipid metabolism in clozapine-treated patients with schizophrenia. Schizophr Res. 2011 Aug; 130(1-3):53-6. PMID: 21565464.
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  76. Berin I, McLellan ST, Macklin EA, Toth TL, Wright DL. Frozen-thawed embryo transfer cycles: clinical outcomes of single and double blastocyst transfers. J Assist Reprod Genet. 2011 Jul; 28(7):575-81. PMID: 21373800; PMCID: PMC3162061.
  77. Hill M, Shannahan K, Jasinski S, Macklin EA, Raeke L, Roffman JL, Goff DC. Folate supplementation in schizophrenia: a possible role for MTHFR genotype. Schizophr Res. 2011 Apr; 127(1-3):41-5. PMID: 21334854.
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  78. Holloway CL, Macklin EA, Cormack RA, Viswanathan AN. Should the organs at risk be contoured in vaginal cuff brachytherapy? Brachytherapy. 2011 Jul-Aug; 10(4):313-7. PMID: 21193355.
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  79. Young GS, Macklin EA, Setayesh K, Lawson JD, Wen PY, Norden AD, Drappatz J, Kesari S. Longitudinal MRI evidence for decreased survival among periventricular glioblastoma. J Neurooncol. 2011 Aug; 104(1):261-9. PMID: 21132516; PMCID: PMC3151407.
  80. Sabatini ME, Wolkovich AM, Macklin EA, Wright DL, Souter I, Toth TL. Pronuclear embryo cryopreservation experience: outcomes for reducing the risk of ovarian hyperstimulation syndrome and for fertility preservation in cancer patients. J Assist Reprod Genet. 2011 Mar; 28(3):279-84. PMID: 21107899; PMCID: PMC3082652.
  81. Ajijola OA, Macklin EA, Moore SA, McCarty D, Bischoff KE, Heist EK, Picard M, Ruskin JN, Dec GW, Singh JP. Inpatient vs. elective outpatient cardiac resynchronization therapy device implantation and long-term clinical outcome. Europace. 2010 Dec; 12(12):1745-9. PMID: 20852289.
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  82. Phan CM, Macklin EA, Bredella MA, Dadrich M, Flechsig P, Yoo AJ, Hirsch JA, Gupta R. Trabecular structure analysis using C-arm CT: comparison with MDCT and flat-panel volume CT. Skeletal Radiol. 2011 Aug; 40(8):1065-72. PMID: 20658286.
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  83. Leeman BA, Macklin EA, Schomer DL, O'Connor MG. Remote memory deficits in epilepsy and the role of failed consolidation. Epilepsy Behav. 2010 Aug; 18(4):498-9. PMID: 20708577.
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  84. Healy BC, Ikle D, Macklin EA, Cutter G. Optimal design and analysis of phase I/II clinical trials in multiple sclerosis with gadolinium-enhanced lesions as the endpoint. Mult Scler. 2010 Jul; 16(7):840-7. PMID: 20530124.
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  85. Wang ML, Macklin EA, Tracy E, Nadel H, Catlin EA. Updated parental viewpoints on male neonatal circumcision in the United States. Clin Pediatr (Phila). 2010 Feb; 49(2):130-6. PMID: 20080519.
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  86. Conboy LA, Macklin E, Kelley J, Kokkotou E, Lembo A, Kaptchuk T. Which patients improve: characteristics increasing sensitivity to a supportive patient-practitioner relationship. Soc Sci Med. 2010 Feb; 70(3):479-84. PMID: 19900742; PMCID: PMC2814899.
  87. Mitha AP, Reichardt B, Grasruck M, Macklin E, Bartling S, Leidecker C, Schmidt B, Flohr T, Brady TJ, Ogilvy CS, Gupta R. Dynamic imaging of a model of intracranial saccular aneurysms using ultra-high-resolution flat-panel volumetric computed tomography. Laboratory investigation. J Neurosurg. 2009 Nov; 111(5):947-57. PMID: 19374491.
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  88. Freudenreich O, Henderson DC, Macklin EA, Evins AE, Fan X, Cather C, Walsh JP, Goff DC. Modafinil for clozapine-treated schizophrenia patients: a double-blind, placebo-controlled pilot trial. J Clin Psychiatry. 2009 Dec; 70(12):1674-80. PMID: 19689921; PMCID: PMC5038350.
  89. Leeman BA, Macklin EA, Schomer DL, O'Connor MG. Transient News Events Test: feasibility in assessment of post-temporal lobectomy remote memory deficits. Epilepsy Behav. 2009 Sep; 16(1):113-9. PMID: 19643674.
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  90. Vogiatzi MG, Macklin EA, Trachtenberg FL, Fung EB, Cheung AM, Vichinsky E, Olivieri N, Kirby M, Kwiatkowski JL, Cunningham M, Holm IA, Fleisher M, Grady RW, Peterson CM, Giardina PJ. Differences in the prevalence of growth, endocrine and vitamin D abnormalities among the various thalassaemia syndromes in North America. Br J Haematol. 2009 Sep; 146(5):546-56. PMID: 19604241; PMCID: PMC2798591.
  91. Vogiatzi MG, Macklin EA, Fung EB, Cheung AM, Vichinsky E, Olivieri N, Kirby M, Kwiatkowski JL, Cunningham M, Holm IA, Lane J, Schneider R, Fleisher M, Grady RW, Peterson CC, Giardina PJ. Bone disease in thalassemia: a frequent and still unresolved problem. J Bone Miner Res. 2009 Mar; 24(3):543-57. PMID: 18505376; PMCID: PMC3276604.
  92. Kesari S, Schiff D, Drappatz J, LaFrankie D, Doherty L, Macklin EA, Muzikansky A, Santagata S, Ligon KL, Norden AD, Ciampa A, Bradshaw J, Levy B, Radakovic G, Ramakrishna N, Black PM, Wen PY. Phase II study of protracted daily temozolomide for low-grade gliomas in adults. Clin Cancer Res. 2009 Jan 01; 15(1):330-7. PMID: 19118062.
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  93. Huang S, Dunkley-Thompson J, Tang Y, Macklin EA, Steel-Duncan J, Singh-Minott I, Ryland EG, Smikle M, Walker BD, Christie CD, Feeney ME. Deficiency of HIV-Gag-specific T cells in early childhood correlates with poor viral containment. J Immunol. 2008 Dec 01; 181(11):8103-11. PMID: 19018003; PMCID: PMC2714370.
  94. Field JJ, Macklin EA, Yan Y, Strunk RC, DeBaun MR. Sibling history of asthma is a risk factor for pain in children with sickle cell anemia. Am J Hematol. 2008 Nov; 83(11):855-7. PMID: 18819094; PMCID: PMC2590666.
  95. Walter PB, Macklin EA, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Vichinsky E, Olivieri N, Alberti D, Holland J, Harmatz P. Inflammation and oxidant-stress in beta-thalassemia patients treated with iron chelators deferasirox (ICL670) or deferoxamine: an ancillary study of the Novartis CICL670A0107 trial. Haematologica. 2008 Jun; 93(6):817-25. PMID: 18469351.
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  96. Valaskatgis P, Macklin EA, Schachter SC, Wayne PM. Possible effects of acupuncture on atrial fibrillation and post-herpetic neuralgia--a case report. Acupunct Med. 2008 Mar; 26(1):51-6. PMID: 18356799.
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  97. Boyd JH, Macklin EA, Strunk RC, DeBaun MR. Asthma is associated with increased mortality in individuals with sickle cell anemia. Haematologica. 2007 Aug; 92(8):1115-8. PMID: 17650441.
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  98. Schaechter JD, Connell BD, Stason WB, Kaptchuk TJ, Krebs DE, Macklin EA, Schnyer RN, Stein J, Scarborough DM, Parker SW, McGibbon CA, Wayne PM. Correlated change in upper limb function and motor cortex activation after verum and sham acupuncture in patients with chronic stroke. J Altern Complement Med. 2007 Jun; 13(5):527-32. PMID: 17604556.
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  99. Macklin EA, Wayne PM, Kalish LA, Valaskatgis P, Thompson J, Pian-Smith MC, Zhang Q, Stevens S, Goertz C, Prineas RJ, Buczynski B, Zusman RM. Stop Hypertension with the Acupuncture Research Program (SHARP): results of a randomized, controlled clinical trial. Hypertension. 2006 Nov; 48(5):838-45. PMID: 17015784.
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  100. Rogers CA, Wayne PM, Macklin EA, Muilenberg ML, Wagner CJ, Epstein PR, Bazzaz FA. Interaction of the onset of spring and elevated atmospheric CO2 on ragweed (Ambrosia artemisiifolia L.) pollen production. Environ Health Perspect. 2006 Jun; 114(6):865-9. PMID: 16759986; PMCID: PMC1480488.
  101. Boyd JH, Macklin EA, Strunk RC, DeBaun MR. Asthma is associated with acute chest syndrome and pain in children with sickle cell anemia. Blood. 2006 Nov 01; 108(9):2923-7. PMID: 16690969; PMCID: PMC1892235.
  102. Wayne PM, Krebs DE, Macklin EA, Schnyer R, Kaptchuk TJ, Parker SW, Scarborough DM, McGibbon CA, Schaechter JD, Stein J, Stason WB. Acupuncture for upper-extremity rehabilitation in chronic stroke: a randomized sham-controlled study. Arch Phys Med Rehabil. 2005 Dec; 86(12):2248-55. PMID: 16344019.
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  103. Vogiatzi MG, Macklin EA, Fung EB, Vichinsky E, Olivieri N, Kwiatkowski J, Cohen A, Neufeld E, Giardina PJ. Prevalence of fractures among the Thalassemia syndromes in North America. Bone. 2006 Apr; 38(4):571-5. PMID: 16298178; PMCID: PMC4594870.
  104. Vichinsky EP, MacKlin EA, Waye JS, Lorey F, Olivieri NF. Changes in the epidemiology of thalassemia in North America: a new minority disease. Pediatrics. 2005 Dec; 116(6):e818-25. PMID: 16291734.
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  105. Lukas SE, Penetar D, Berko J, Vicens L, Palmer C, Mallya G, Macklin EA, Lee DY. An extract of the Chinese herbal root kudzu reduces alcohol drinking by heavy drinkers in a naturalistic setting. Alcohol Clin Exp Res. 2005 May; 29(5):756-62. PMID: 15897719.
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  106. Hopper JW, Karlsgodt KH, Adler CM, Macklin EA, Lukas SE, Elman I. Effects of acute cortisol and cocaine administration on attention, recall and recognition task performance in individuals with cocaine dependence. Hum Psychopharmacol. 2004 Oct; 19(7):511-6. PMID: 15378675.
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  107. Cunningham MJ, Macklin EA, Neufeld EJ, Cohen AR. Complications of beta-thalassemia major in North America. Blood. 2004 Jul 01; 104(1):34-9. PMID: 14988152.
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  108. Kalish LA, Buczynski B, Connell P, Gemmel A, Goertz C, Macklin EA, Pian-Smith M, Stevens S, Thompson J, Valaskatgis P, Wayne PM, Zusman RM. Stop Hypertension with the Acupuncture Research Program (SHARP): clinical trial design and screening results. Control Clin Trials. 2004 Feb; 25(1):76-103. PMID: 14980754.
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  109. Pegelow CH, Macklin EA, Moser FG, Wang WC, Bello JA, Miller ST, Vichinsky EP, DeBaun MR, Guarini L, Zimmerman RA, Younkin DP, Gallagher DM, Kinney TR. Longitudinal changes in brain magnetic resonance imaging findings in children with sickle cell disease. Blood. 2002 Apr 15; 99(8):3014-8. PMID: 11929794.
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  110. Miller ST, Macklin EA, Pegelow CH, Kinney TR, Sleeper LA, Bello JA, DeWitt LD, Gallagher DM, Guarini L, Moser FG, Ohene-Frempong K, Sanchez N, Vichinsky EP, Wang WC, Wethers DL, Younkin DP, Zimmerman RA, DeBaun MR. Silent infarction as a risk factor for overt stroke in children with sickle cell anemia: a report from the Cooperative Study of Sickle Cell Disease. J Pediatr. 2001 Sep; 139(3):385-90. PMID: 11562618.
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