Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Tammy Ting Hshieh, M.D.

Title
Institution
Department
Address

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. DuMontier C, Uno H, Hshieh T, Zhou G, Chen R, Magnavita ES, Mozessohn L, Javedan H, Stone RM, Soiffer RJ, Driver JA, Abel GA. Randomized controlled trial of geriatric consultation versus standard care in older adults with hematologic malignancies. Haematologica. 2021 Sep 23. PMID: 34551505.
    Citations:    Fields:    
  2. Cooper L, Loewenthal J, Frain LN, Tulebaev S, Cardin K, Hshieh TT, Dumontier C, Streiter S, Joseph C, Hilt A, Theou O, Rockwood K, Orkaby AR, Javedan H. From research to bedside: Incorporation of a CGA-based frailty index among multiple comanagement services. J Am Geriatr Soc. 2021 Sep 13. PMID: 34519037.
    Citations:    Fields:    
  3. Jones RN, Tommet D, Steingrimsson J, Racine AM, Fong TG, Gou Y, Hshieh TT, Metzger ED, Schmitt EM, Tabloski PA, Travison TG, Vasunilashorn SM, Abdeen A, Earp B, Kunze L, Lange J, Vlassakov K, Dickerson BC, Marcantonio ER, Inouye SK. Development and internal validation of a predictive model of cognitive decline 36 months following elective surgery. Alzheimers Dement (Amst). 2021; 13(1):e12201. PMID: 34046520.
    Citations:    
  4. Gou RY, Hshieh TT, Marcantonio ER, Cooper Z, Jones RN, Travison TG, Fong TG, Abdeen A, Lange J, Earp B, Schmitt EM, Leslie DL, Inouye SK. One-Year Medicare Costs Associated With Delirium in Older Patients Undergoing Major Elective Surgery. JAMA Surg. 2021 May 01; 156(5):430-442. PMID: 33625501.
    Citations: 1     Fields:    
  5. Kennedy M, Webb M, Gartaganis S, Hwang U, Biese K, Stuck A, Lesser A, Hshieh T, Inouye SK. ED-DEL: Development of a change package and toolkit for delirium in the emergency department. J Am Coll Emerg Physicians Open. 2021 Apr; 2(2):e12421. PMID: 33969341.
    Citations:    
  6. Bahl NE, Magnavita ES, Hshieh T, Testa M, Kim D, Manor B, Driver JA, Abel GA, DuMontier C. Objective performance tests of cognition and physical function as part of a virtual geriatric assessment. J Geriatr Oncol. 2021 Mar 29. PMID: 33795206.
    Citations:    Fields:    
  7. Fong TG, Vasunilashorn SM, Gou Y, Libermann TA, Dillon S, Schmitt E, Arnold SE, Kivisäkk P, Carlyle B, Oh ES, Vlassakov K, Kunze L, Hshieh T, Jones RN, Marcantonio ER, Inouye SK. Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults. Alzheimers Dement (N Y). 2021; 7(1):e12125. PMID: 33748398.
    Citations:    
  8. Loewenthal J, DuMontier C, Cooper L, Frain L, Waldman LS, Streiter S, Cardin K, Tulebaev S, Javedan H, Orkaby AR, Hshieh T. Adaptation of the comprehensive geriatric assessment to a virtual delivery format. Age Ageing. 2021 02 26; 50(2):597-598. PMID: 33284967.
    Citations:    Fields:    Translation:Humans
  9. Hantel A, DuMontier C, Odejide OO, Luskin MR, Sperling AS, Hshieh T, Chen R, Soiffer R, Driver JA, Abel GA. Gait speed, survival, and recommended treatment intensity in older adults with blood cancer requiring treatment. Cancer. 2021 03 15; 127(6):875-883. PMID: 33237587.
    Citations: 1     Fields:    
  10. Helfand BKI, D'Aquila ML, Tabloski P, Erickson K, Yue J, Fong TG, Hshieh TT, Metzger ED, Schmitt EM, Boudreaux ED, Inouye SK, Jones RN. Detecting Delirium: A Systematic Review of Identification Instruments for Non-ICU Settings. J Am Geriatr Soc. 2021 02; 69(2):547-555. PMID: 33135780.
    Citations:    Fields:    Translation:Humans
  11. Kennedy M, Helfand BKI, Gou RY, Gartaganis SL, Webb M, Moccia JM, Bruursema SN, Dokic B, McCulloch B, Ring H, Margolin JD, Zhang E, Anderson R, Babine RL, Hshieh T, Wong AH, Taylor RA, Davenport K, Teresi B, Fong TG, Inouye SK. Delirium in Older Patients With COVID-19 Presenting to the Emergency Department. JAMA Netw Open. 2020 11 02; 3(11):e2029540. PMID: 33211114.
    Citations: 34     Fields:    Translation:Humans
  12. Racine AM, Tommet D, D'Aquila ML, Fong TG, Gou Y, Tabloski PA, Metzger ED, Hshieh TT, Schmitt EM, Vasunilashorn SM, Kunze L, Vlassakov K, Abdeen A, Lange J, Earp B, Dickerson BC, Marcantonio ER, Steingrimsson J, Travison TG, Inouye SK, Jones RN. Machine Learning to Develop and Internally Validate a Predictive Model for Post-operative Delirium in a Prospective, Observational Clinical Cohort Study of Older Surgical Patients. J Gen Intern Med. 2021 02; 36(2):265-273. PMID: 33078300.
    Citations: 3     Fields:    Translation:Humans
  13. Vasunilashorn SM, Schulman-Green D, Tommet D, Fong TG, Hshieh TT, Marcantonio ER, Metzger ED, Schmitt EM, Tabloski PA, Travison TG, Gou Y, Helfand B, Inouye SK, Jones RN. New Delirium Severity Indicators: Generation and Internal Validation in the Better Assessment of Illness (BASIL) Study. Dement Geriatr Cogn Disord. 2020; 49(1):77-90. PMID: 32554974.
    Citations:    Fields:    Translation:Humans
  14. Hshieh TT, Inouye SK, Oh ES. Delirium in the Elderly. Clin Geriatr Med. 2020 05; 36(2):183-199. PMID: 32222295.
    Citations: 2     Fields:    Translation:Humans
  15. Hshieh TT, Fong TG, Schmitt EM, Marcantonio ER, Xu G, Gou YR, Travison TG, Metzger ED, Jones RN, Inouye SK. Does Alzheimer's Disease and Related Dementias Modify Delirium Severity and Hospital Outcomes? J Am Geriatr Soc. 2020 08; 68(8):1722-1730. PMID: 32255521.
    Citations: 1     Fields:    Translation:Humans
  16. DuMontier C, Loh KP, Bain PA, Silliman RA, Hshieh T, Abel GA, Djulbegovic B, Driver JA, Dale W. Defining Undertreatment and Overtreatment in Older Adults With Cancer: A Scoping Literature Review. J Clin Oncol. 2020 08 01; 38(22):2558-2569. PMID: 32250717.
    Citations: 13     Fields:    Translation:Humans
  17. Ward RE, Orkaby AR, Chen J, Hshieh TT, Driver JA, Gaziano JM, Djousse L. Association between Diet Quality and Frailty Prevalence in the Physicians' Health Study. J Am Geriatr Soc. 2020 04; 68(4):770-776. PMID: 31840808.
    Citations: 7     Fields:    Translation:Humans
  18. Hshieh TT, Vasunilashorn SM, D'Aquila ML, Arnold SE, Dickerson BC, Fong TG, Jones RN, Marcantonio ER, Schmitt EM, Xu G, Gou Y, Chen F, Kunze LJ, Vlassakov KV, Abdeen AR, Lange JK, Earp BE, Touroutoglou A, Carlyle BC, Kivisakk-Webb P, Travison TG, Dillon ST, Libermann TA, Inouye SK. The Role of Inflammation after Surgery for Elders (RISE) study: Study design, procedures, and cohort profile. Alzheimers Dement (Amst). 2019 Dec; 11:752-762. PMID: 31737775.
    Citations: 7     
  19. Fong TG, Racine AM, Fick DM, Tabloski P, Gou Y, Schmitt EM, Hshieh TT, Metzger E, Bertrand SE, Marcantonio ER, Jones RN, Inouye SK. The Caregiver Burden of Delirium in Older Adults With Alzheimer Disease and Related Disorders. J Am Geriatr Soc. 2019 12; 67(12):2587-2592. PMID: 31605539.
    Citations: 3     Fields:    Translation:Humans
  20. Daiello LA, Racine AM, Yun Gou R, Marcantonio ER, Xie Z, Kunze LJ, Vlassakov KV, Inouye SK, Jones RN, Alsop D, Travison T, Arnold S, Cooper Z, Dickerson B, Fong T, Metzger E, Pascual-Leone A, Schmitt EM, Shafi M, Cavallari M, Dai W, Dillon ST, McElhaney J, Guttmann C, Hshieh T, Kuchel G, Libermann T, Ngo L, Press D, Saczynski J, Vasunilashorn S, O'Connor M, Kimchi E, Strauss J, Wong B, Belkin M, Ayres D, Callery M, Pomposelli F, Wright J, Schermerhorn M, Abrantes T, Albuquerque A, Bertrand S, Brown A, Callahan A, D'Aquila M, Dowal S, Fox M, Gallagher J, Anna Gersten R, Hodara A, Helfand B, Inloes J, Kettell J, Kuczmarska A, Nee J, Nemeth E, Ochsner L, Palihnich K, Parisi K, Puelle M, Rastegar S, Vella M, Xu G, Bryan M, Guess J, Enghorn D, Gross A, Gou Y, Habtemariam D, Isaza I, Kosar C, Rockett C, Tommet D, Gruen T, Ross M, Tasker K, Gee J, Kolanowski A, Pisani M, de Rooij S, Rogers S, Studenski S, Stern Y, Whittemore A, Gottlieb G, Orav J, Sperling R. Postoperative Delirium and Postoperative Cognitive Dysfunction: Overlap and Divergence. Anesthesiology. 2019 09; 131(3):477-491. PMID: 31166241.
    Citations: 24     Fields:    Translation:Humans
  21. Doolin JW, Halpin M, Berry JL, Hshieh T, Zerillo JA. Why focus on patient-reported outcome measures in older colorectal cancer patients? Eur J Surg Oncol. 2020 03; 46(3):394-401. PMID: 31377032.
    Citations:    Fields:    Translation:Humans
  22. Liu MA, DuMontier C, Murillo A, Hshieh TT, Bean JF, Soiffer RJ, Stone RM, Abel GA, Driver JA. Gait speed, grip strength, and clinical outcomes in older patients with hematologic malignancies. Blood. 2019 07 25; 134(4):374-382. PMID: 31167800.
    Citations: 31     Fields:    Translation:HumansPHPublic Health
  23. DuMontier C, Liu MA, Murillo A, Hshieh T, Javedan H, Soiffer R, Stone RM, Driver JA, Abel GA. Function, Survival, and Care Utilization Among Older Adults With Hematologic Malignancies. J Am Geriatr Soc. 2019 05; 67(5):889-897. PMID: 30945759.
    Citations: 7     Fields:    Translation:Humans
  24. Jones RN, Cizginer S, Pavlech L, Albuquerque A, Daiello LA, Dharmarajan K, Gleason LJ, Helfand B, Massimo L, Oh E, Okereke OI, Tabloski P, Rabin LA, Yue J, Marcantonio ER, Fong TG, Hshieh TT, Metzger ED, Erickson K, Schmitt EM, Inouye SK. Assessment of Instruments for Measurement of Delirium Severity: A Systematic Review. JAMA Intern Med. 2019 02 01; 179(2):231-239. PMID: 30556827.
    Citations: 10     Fields:    Translation:Humans
  25. Hshieh TT, Driver JA, Abel GA. Cognitive Impairment Among Older Patients With Hematologic Cancers-Reply. JAMA Oncol. 2018 12 01; 4(12):1784. PMID: 30286229.
    Citations:    Fields:    Translation:Humans
  26. Murillo A, Cronin AM, Laubach JP, Hshieh TT, Tanasijevic AM, Richardson PG, Driver JA, Abel GA. Performance of the International Myeloma Working Group myeloma frailty score among patients 75 and older. J Geriatr Oncol. 2019 05; 10(3):486-489. PMID: 30472368.
    Citations: 7     Fields:    Translation:Humans
  27. Hshieh TT, Fong TG, Schmitt EM, Marcantonio ER, D'Aquila ML, Gallagher J, Xu G, Guo YR, Abrantes TF, Bertrand SE, Jones RN, Inouye SK. The Better Assessment of Illness Study for Delirium Severity: Study Design, Procedures, and Cohort Description. Gerontology. 2019; 65(1):20-29. PMID: 30032141.
    Citations: 4     Fields:    Translation:Humans
  28. Hshieh TT, Yang T, Gartaganis SL, Yue J, Inouye SK. Hospital Elder Life Program: Systematic Review and Meta-analysis of Effectiveness. Am J Geriatr Psychiatry. 2018 10; 26(10):1015-1033. PMID: 30076080.
    Citations: 34     Fields:    Translation:Humans
  29. Ha A, Krasnow RE, Mossanen M, Nagle R, Hshieh TT, Rudolph JL, Chang SL. A contemporary population-based analysis of the incidence, cost, and outcomes of postoperative delirium following major urologic cancer surgeries. Urol Oncol. 2018 Jul; 36(7):341.e15-341.e22. PMID: 29801992.
    Citations: 5     Fields:    Translation:Humans
  30. Hshieh TT, Jung WF, Grande LJ, Chen J, Stone RM, Soiffer RJ, Driver JA, Abel GA. Prevalence of Cognitive Impairment and Association With Survival Among Older Patients With Hematologic Cancers. JAMA Oncol. 2018 05 01; 4(5):686-693. PMID: 29494732.
    Citations: 25     Fields:    Translation:Humans
  31. Hshieh TT, Inouye SK, Oh ES. Delirium in the Elderly. Psychiatr Clin North Am. 2018 03; 41(1):1-17. PMID: 29412839.
    Citations: 12     Fields:    Translation:Humans
  32. Oh ES, Fong TG, Hshieh TT, Inouye SK. Delirium in Older Persons: Advances in Diagnosis and Treatment. JAMA. 2017 09 26; 318(12):1161-1174. PMID: 28973626.
    Citations: 73     Fields:    Translation:Humans
  33. Kimchi EY, Hshieh TT, Guo R, Wong B, O'Connor M, Marcantonio ER, Metzger ED, Strauss J, Arnold SE, Inouye SK, Fong TG. Consensus Approaches to Identify Incident Dementia in Cohort Studies: Systematic Review and Approach in the Successful Aging after Elective Surgery Study. J Am Med Dir Assoc. 2017 Dec 01; 18(12):1010-1018.e1. PMID: 28927945.
    Citations: 7     Fields:    Translation:Humans
  34. Cavallari M, Dai W, Guttmann CRG, Meier DS, Ngo LH, Hshieh TT, Fong TG, Schmitt E, Press DZ, Travison TG, Marcantonio ER, Jones RN, Inouye SK, Alsop DC. Longitudinal diffusion changes following postoperative delirium in older people without dementia. Neurology. 2017 Sep 05; 89(10):1020-1027. PMID: 28779010.
    Citations: 5     Fields:    Translation:Humans
  35. Hshieh TT, Saczynski J, Gou RY, Marcantonio E, Jones RN, Schmitt E, Cooper Z, Ayres D, Wright J, Travison TG, Inouye SK. Trajectory of Functional Recovery After Postoperative Delirium in Elective Surgery. Ann Surg. 2017 04; 265(4):647-653. PMID: 27501176.
    Citations: 25     Fields:    Translation:Humans
  36. Orkaby AR, Hshieh TT, Gaziano JM, Djousse L, Driver JA. Comparison of two frailty indices in the physicians' health study. Arch Gerontol Geriatr. 2017 Jul; 71:21-27. PMID: 28242579.
    Citations: 6     Fields:    Translation:Humans
  37. Liu MA, Hshieh T, Condron N, Wadleigh M, Abel GA, Driver JA. Relationship between physician and patient assessment of performance status and survival in a large cohort of patients with haematologic malignancies. Br J Cancer. 2016 09 27; 115(7):858-61. PMID: 27552440.
    Citations: 3     Fields:    Translation:Humans
  38. Bunker L, Hshieh TT, Wong B, Schmitt EM, Travison T, Yee J, Palihnich K, Metzger E, Fong TG, Inouye SK. The SAGES telephone neuropsychological battery: correlation with in-person measures. Int J Geriatr Psychiatry. 2017 09; 32(9):991-999. PMID: 27507320.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  39. Cavallari M, Dai W, Guttmann CR, Meier DS, Ngo LH, Hshieh TT, Callahan AE, Fong TG, Schmitt E, Dickerson BC, Press DZ, Marcantonio ER, Jones RN, Inouye SK, Alsop DC. Neural substrates of vulnerability to postsurgical delirium as revealed by presurgical diffusion MRI. Brain. 2016 Apr; 139(Pt 4):1282-94. PMID: 26920674.
    Citations: 17     Fields:    Translation:Humans
  40. Hshieh TT, Dai W, Cavallari M, Guttmann CR, Meier DS, Schmitt EM, Dickerson BC, Press DZ, Marcantonio ER, Jones RN, Gou YR, Travison TG, Fong TG, Ngo L, Inouye SK, Alsop DC. Cerebral blood flow MRI in the nondemented elderly is not predictive of post-operative delirium but is correlated with cognitive performance. J Cereb Blood Flow Metab. 2017 Apr; 37(4):1386-1397. PMID: 27401806.
    Citations: 6     Fields:    Translation:Humans
  41. Hshieh TT, Fox ML, Kosar CM, Cavallari M, Guttmann CR, Alsop D, Marcantonio ER, Schmitt EM, Jones RN, Inouye SK. Head circumference as a useful surrogate for intracranial volume in older adults. Int Psychogeriatr. 2016 Jan; 28(1):157-62. PMID: 26631180.
    Citations: 3     Fields:    Translation:Humans
  42. Hshieh TT, Kaung A, Hussain S, Curry MP, Sundaram V. The international normalized ratio does not reflect bleeding risk in esophageal variceal hemorrhage. Saudi J Gastroenterol. 2015 Jul-Aug; 21(4):254-8. PMID: 26228370.
    Citations: 1     Fields:    Translation:Humans
  43. Fong TG, Hshieh TT, Wong B, Tommet D, Jones RN, Schmitt EM, Puelle MR, Saczynski JS, Marcantonio ER, Inouye SK. Neuropsychological profiles of an elderly cohort undergoing elective surgery and the relationship between cognitive performance and delirium. J Am Geriatr Soc. 2015 May; 63(5):977-82. PMID: 25944109.
    Citations: 17     Fields:    Translation:Humans
  44. Chen P, Dowal S, Schmitt E, Habtemariam D, Hshieh TT, Victor R, Boockvar KS, Inouye SK. Hospital Elder Life Program in the real world: the many uses of the Hospital Elder Life Program website. J Am Geriatr Soc. 2015 Apr; 63(4):797-803. PMID: 25877747.
    Citations: 2     Fields:    
  45. Hshieh TT, Yue J, Oh E, Puelle M, Dowal S, Travison T, Inouye SK. Effectiveness of multicomponent nonpharmacological delirium interventions: a meta-analysis. JAMA Intern Med. 2015 Apr; 175(4):512-20. PMID: 25643002.
    Citations: 100     Fields:    Translation:Humans
  46. Cavallari M, Hshieh TT, Guttmann CR, Ngo LH, Meier DS, Schmitt EM, Marcantonio ER, Jones RN, Kosar CM, Fong TG, Press D, Inouye SK, Alsop DC. Brain atrophy and white-matter hyperintensities are not significantly associated with incidence and severity of postoperative delirium in older persons without dementia. Neurobiol Aging. 2015 Jun; 36(6):2122-9. PMID: 25824618.
    Citations: 22     Fields:    Translation:Humans
  47. Hshieh TT, Petrone AB, Gaziano JM, Djoussé L. Nut consumption and risk of mortality in the Physicians' Health Study. Am J Clin Nutr. 2015 Feb; 101(2):407-12. PMID: 25646339.
    Citations: 19     Fields:    Translation:Humans
  48. Saczynski JS, Inouye SK, Kosar CM, Tommet D, Marcantonio ER, Fong T, Hshieh T, Vasunilashorn S, Metzger ED, Schmitt E, Alsop DC, Jones RN. Cognitive and brain reserve and the risk of postoperative delirium in older patients: analysis of data from a prospective observational study. Lancet Psychiatry. 2014 Nov; 1(6):437-43. PMID: 26361198.
    Citations: 13     Fields:    
  49. Saczynski JS, Inouye SK, Kosar C, Tommet D, Marcantonio ER, Fong T, Hshieh T, Vasunilashorn S, Metzger ED, Schmitt E, Alsop DC, Jones RN. Cognitive and Brain Reserve and the Risk of Postoperative Delirium in Older Patients. Lancet Psychiatry. 2014 Nov; 1(6):437-443. PMID: 25642414.
    Citations: 7     Fields:    
  50. Hshieh TT, Sundaram V. Liver transplantation for hepatocellular carcinoma: are international guidelines possible? Hepatobiliary Surg Nutr. 2013 Apr; 2(2):113-6. PMID: 24570925.
    Citations:    
  51. Hshieh TT, Sundaram V, Najarian RM, Hanto DW, Karp SJ, Curry MP. Hepatitis B surface antigen as a marker for recurrent, metastatic hepatocellular carcinoma after liver transplantation. Liver Transpl. 2012 Aug; 18(8):995-8. PMID: 22829419.
    Citations: 1     Fields:    Translation:Humans
  52. Jones PB, Adams KW, Rozkalne A, Spires-Jones TL, Hshieh TT, Hashimoto T, von Armin CA, Mielke M, Bacskai BJ, Hyman BT. Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-ß in human Alzheimer brain. PLoS One. 2011 Jan 31; 6(1):e14586. PMID: 21297948.
    Citations: 37     Fields:    Translation:HumansCells
  53. Hshieh TT, Fong TG, Marcantonio ER, Inouye SK. Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence. J Gerontol A Biol Sci Med Sci. 2008 Jul; 63(7):764-72. PMID: 18693233.
    Citations: 99     Fields:    Translation:Humans
  54. Mach J, Hshieh T, Hsieh D, Grubbs N, Chervonsky A. Development of intestinal M cells. Immunol Rev. 2005 Aug; 206:177-89. PMID: 16048549.
    Citations: 33     Fields:    Translation:HumansAnimals
  55. von Arnim CA, Kinoshita A, Peltan ID, Tangredi MM, Herl L, Lee BM, Spoelgen R, Hshieh TT, Ranganathan S, Battey FD, Liu CX, Bacskai BJ, Sever S, Irizarry MC, Strickland DK, Hyman BT. The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate. J Biol Chem. 2005 May 06; 280(18):17777-85. PMID: 15749709.
    Citations: 107     Fields:    Translation:HumansAnimalsCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Hshieh's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (172)
Explore
_
Co-Authors (72)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.