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profileKalpathy Subramaniam Krishnamoorthy, M.D., M.B.,B.S.

TitleAssociate Professor of Pediatrics (Neurology)
InstitutionMassachusetts General Hospital
DepartmentPediatrics
AddressMassachusetts General Hospital
Pediatric Neurology Unit WANG 708
55 Fruit St
Boston MA 02114
Phone617/726-3877
Fax617/724-7860
vCardDownload vCard (login for email)

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Fuller JC, Sinha S, Caruso PA, Hersh CJ, Butler WE, Krishnamoorthy KS, Hartnick CJ. Chiari malformations: An important cause of pediatric aspiration. Int J Pediatr Otorhinolaryngol. 2016 Sep; 88:124-8. PMID: 27497399.
    View in: PubMed
  2. Krishnamoorthy KS, Eichler F, Rapalino O, Frosch MP. Case records of the Massachusetts General Hospital. Case 14-2014. An 11-month-old girl with developmental delay. N Engl J Med. 2014 May 08; 370(19):1830-41. PMID: 24806163.
    View in: PubMed
  3. Shriram AN, Krishnamoorthy K, Sivan A, Saha BP, Kumaraswami V, Vijayachari P. Impact of MDA and the prospects of elimination of the lone focus of diurnally sub periodic lymphatic filariasis in Nicobar Islands, India. Acta Trop. 2014 May; 133:93-7. PMID: 24556139.
    View in: PubMed
  4. Pienaar R, Paldino MJ, Madan N, Krishnamoorthy KS, Alsop DC, Dehaes M, Grant PE. A quantitative method for correlating observations of decreased apparent diffusion coefficient with elevated cerebral blood perfusion in newborns presenting cerebral ischemic insults. Neuroimage. 2012 Nov 15; 63(3):1510-8. PMID: 22892333.
    View in: PubMed
  5. Vendrame M, Maski KP, Chatterjee M, Heshmati A, Krishnamoorthy K, Tan WH, Kothare SV. Epilepsy in Prader-Willi syndrome: clinical characteristics and correlation to genotype. Epilepsy Behav. 2010 Nov; 19(3):306-10. PMID: 20727826.
    View in: PubMed
  6. Krishnamoorthy KS, Kuban KC, O'Shea TM, Westra SJ, Allred EN, Leviton A. Early cranial ultrasound lesions predict microcephaly at age 2 years in preterm infants. J Child Neurol. 2011 Feb; 26(2):188-94. PMID: 20724751; PMCID: PMC4741104.
  7. Shenoy AM, Markowitz JA, Bonnemann CG, Krishnamoorthy K, Bossler AD, Tseng BS. Muscle-Eye-Brain disease. J Clin Neuromuscul Dis. 2010 Mar; 11(3):124-6. PMID: 20215985; PMCID: PMC2925645.
  8. Krishnamoorthy KS, Eichler FS, Goyal NA, Small JE, Snuderl M. Case records of the Massachusetts General Hospital. Case 3-2010. A 5-month-old boy with developmental delay and irritability. N Engl J Med. 2010 Jan 28; 362(4):346-56. PMID: 20107221.
    View in: PubMed
  9. Brass SD, Dinkin MJ, Williams Z, Krishnamoorthy KS, Copen WA, Freeman SH. Case Records of the Massachusetts General Hospital. Case 38-2009 - a 16-year-old boy with paroxysmal headaches and visual changes. N Engl J Med. 2009 Dec 10; 361(24):2367-78. PMID: 20007563.
    View in: PubMed
  10. Travaglini L, Brancati F, Attie-Bitach T, Audollent S, Bertini E, Kaplan J, Perrault I, Iannicelli M, Mancuso B, Rigoli L, Rozet JM, Swistun D, Tolentino J, Dallapiccola B, Gleeson JG, Valente EM, Zankl A, Leventer R, Grattan-Smith P, Janecke A, D'Hooghe M, Sznajer Y, Van Coster R, Demerleir L, Dias K, Moco C, Moreira A, Kim CA, Maegawa G, Petkovic D, Abdel-Salam GM, Abdel-Aleem A, Zaki MS, Marti I, Quijano-Roy S, Sigaudy S, de Lonlay P, Romano S, Touraine R, Koenig M, Lagier-Tourenne C, Messer J, Collignon P, Wolf N, Philippi H, Kitsiou Tzeli S, Halldorsson S, Johannsdottir J, Ludvigsson P, Phadke SR, Udani V, Stuart B, Magee A, Lev D, Michelson M, Ben-Zeev B, Fischetto R, Benedicenti F, Stanzial F, Borgatti R, Accorsi P, Battaglia S, Fazzi E, Giordano L, Pinelli L, Boccone L, Bigoni S, Ferlini A, Donati MA, Caridi G, Divizia MT, Faravelli F, Ghiggeri G, Pessagno A, Briguglio M, Briuglia S, Salpietro CD, Tortorella G, Adami A, Castorina P, Lalatta F, Marra G, Riva D, Scelsa B, Spaccini L, Uziel G, Del Giudice E, Laverda AM, Ludwig K, Permunian A, Suppiej A, Signorini S, Uggetti C, Battini R, Di Giacomo M, Cilio MR, Di Sabato ML, Leuzzi V, Parisi P, Pollazzon M, Silengo M, De Vescovi R, Greco D, Romano C, Cazzagon M, Simonati A, Al-Tawari AA, Bastaki L, Mégarbané A, Sabolic Avramovska V, de Jong MM, Stromme P, Koul R, Rajab A, Azam M, Barbot C, Martorell Sampol L, Rodriguez B, Pascual-Castroviejo I, Teber S, Anlar B, Comu S, Karaca E, Kayserili H, Yüksel A, Akcakus M, Al Gazali L, Sztriha L, Nicholl D, Woods CG, Bennett C, Hurst J, Sheridan E, Barnicoat A, Hennekam R, Lees M, Blair E, Bernes S, Sanchez H, Clark AE, DeMarco E, Donahue C, Sherr E, Hahn J, Sanger TD, Gallager TE, Dobyns WB, Daugherty C, Krishnamoorthy KS, Sarco D, Walsh CA, McKanna T, Milisa J, Chung WK, De Vivo DC, Raynes H, Schubert R, Seward A, Brooks DG, Goldstein A, Caldwell J, Finsecke E, Maria BL, Holden K, Cruse RP, Swoboda KJ, Viskochil D. Expanding CEP290 mutational spectrum in ciliopathies. Am J Med Genet A. 2009 Oct; 149A(10):2173-80. PMID: 19764032; PMCID: PMC4340070.
  11. Grant PE, Roche-Labarbe N, Surova A, Themelis G, Selb J, Warren EK, Krishnamoorthy KS, Boas DA, Franceschini MA. Increased cerebral blood volume and oxygen consumption in neonatal brain injury. J Cereb Blood Flow Metab. 2009 Oct; 29(10):1704-13. PMID: 19675563; PMCID: PMC2762197.
  12. Kuban KC, Allred EN, O'Shea TM, Paneth N, Pagano M, Dammann O, Leviton A, Du Plessis A, Westra SJ, Miller CR, Bassan H, Krishnamoorthy K, Junewick J, Olomu N, Romano E, Seibert J, Engelke S, Karna P, Batton D, O'Connor SE, Keller CE. Cranial ultrasound lesions in the NICU predict cerebral palsy at age 2 years in children born at extremely low gestational age. J Child Neurol. 2009 Jan; 24(1):63-72. PMID: 19168819; PMCID: PMC2814246.
  13. Tierney TS, Tierney BJ, Rosenberg AE, Krishnamoorthy KS, Butler WE. Infantile myofibromatosis: a nontraumatic cause of neonatal brachial plexus palsy. Pediatr Neurol. 2008 Oct; 39(4):276-8. PMID: 18805367.
    View in: PubMed
  14. Redline RW, Sagar P, King ME, Krishnamoorthy KS, Grabowski EF, Roberts DJ. Case records of the Massachusetts General Hospital. Case 12-2008. A newborn infant with intermittent apnea and seizures. N Engl J Med. 2008 Apr 17; 358(16):1713-23. PMID: 18420504.
    View in: PubMed
  15. Eichler F, Krishnamoorthy K, Grant PE. Magnetic resonance imaging evaluation of possible neonatal sinovenous thrombosis. Pediatr Neurol. 2007 Nov; 37(5):317-23. PMID: 17950416.
    View in: PubMed
  16. Grabowski EF, Buonanno FS, Krishnamoorthy K. Prothrombotic risk factors in the evaluation and management of perinatal stroke. Semin Perinatol. 2007 Aug; 31(4):243-9. PMID: 17825681.
    View in: PubMed
  17. Mikati MA, Chaaban HR, Karam PE, Krishnamoorthy KS. Brain malformation and infantile spasms in a SCAD deficiency patient. Pediatr Neurol. 2007 Jan; 36(1):48-50. PMID: 17162197.
    View in: PubMed
  18. Kerrigan JF, Ng YT, Prenger E, Krishnamoorthy KS, Wang NC, Rekate HL. Hypothalamic hamartoma and infantile spasms. Epilepsia. 2007 Jan; 48(1):89-95. PMID: 17241213.
    View in: PubMed
  19. Eichler F, Tan WH, Shih VE, Grant PE, Krishnamoorthy K. Proton magnetic resonance spectroscopy and diffusion-weighted imaging in isolated sulfite oxidase deficiency. J Child Neurol. 2006 Sep; 21(9):801-5. PMID: 16970890.
    View in: PubMed
  20. Nishida M, Makris N, Kennedy DN, Vangel M, Fischl B, Krishnamoorthy KS, Caviness VS, Grant PE. Detailed semiautomated MRI based morphometry of the neonatal brain: preliminary results. Neuroimage. 2006 Sep; 32(3):1041-9. PMID: 16857388.
    View in: PubMed
  21. Kang PB, Krishnamoorthy KS, Jones RM, Shapiro FD, Darras BT. Atypical presentations of spinal muscular atrophy type III (Kugelberg-Welander disease). Neuromuscul Disord. 2006 Aug; 16(8):492-4. PMID: 16797181.
    View in: PubMed
  22. Valente EM, Brancati F, Silhavy JL, Castori M, Marsh SE, Barrano G, Bertini E, Boltshauser E, Zaki MS, Abdel-Aleem A, Abdel-Salam GM, Bellacchio E, Battini R, Cruse RP, Dobyns WB, Krishnamoorthy KS, Lagier-Tourenne C, Magee A, Pascual-Castroviejo I, Salpietro CD, Sarco D, Dallapiccola B, Gleeson JG. AHI1 gene mutations cause specific forms of Joubert syndrome-related disorders. Ann Neurol. 2006 Mar; 59(3):527-34. PMID: 16453322.
    View in: PubMed
  23. Kuban KC, O'Shea M, Allred E, Leviton A, Gilmore H, DuPlessis A, Krishnamoorthy K, Hahn C, Soul J, O'Connor SE, Miller K, Church PT, Keller C, Bream R, Adair R, Miller A, Romano E, Bassan H, Kerkering K, Engelke S, Marshall D, Milowic K, Wereszczak J, Hubbard C, Washburn L, Dillard R, Heller C, Burdo-Hartman W, Fagerman L, Sutton D, Karna P, Olomu N, Caldarelli L, Oca M, Lohr K, Scheiner A. Video and CD-ROM as a training tool for performing neurologic examinations of 1-year-old children in a multicenter epidemiologic study. J Child Neurol. 2005 Oct; 20(10):829-31. PMID: 16417880.
    View in: PubMed
  24. Tan WH, Eichler FS, Hoda S, Lee MS, Baris H, Hanley CA, Grant PE, Krishnamoorthy KS, Shih VE. Isolated sulfite oxidase deficiency: a case report with a novel mutation and review of the literature. Pediatrics. 2005 Sep; 116(3):757-66. PMID: 16140720.
    View in: PubMed
  25. Soman TB, Krishnamoorthy KS. Paroxysmal non-epileptic events resembling seizures in children with otitis media. Clin Pediatr (Phila). 2005 Jun; 44(5):437-41. PMID: 15965551.
    View in: PubMed
  26. Moran LR, Cincotta T, Krishnamoorthy K, Insoft RM. The use of baclofen in full-term neonates with hypertonia. J Perinatol. 2005 Jan; 25(1):66-8. PMID: 15608621.
    View in: PubMed
  27. Subramanian S, Stolk WA, Ramaiah KD, Plaisier AP, Krishnamoorthy K, Van Oortmarssen GJ, Dominic Amalraj D, Habbema JD, Das PK. The dynamics of Wuchereria bancrofti infection: a model-based analysis of longitudinal data from Pondicherry, India. Parasitology. 2004 May; 128(Pt 5):467-82. PMID: 15180315.
    View in: PubMed
  28. Modlin JF, Grant PE, Makar RS, Roberts DJ, Krishnamoorthy KS. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 25-2003. A newborn boy with petechiae and thrombocytopenia. N Engl J Med. 2003 Aug 14; 349(7):691-700. PMID: 12917307.
    View in: PubMed
  29. Yoshii A, Krishnamoorthy KS, Grant PE. Abnormal cortical development shown by 3D MRI in Prader-Willi syndrome. Neurology. 2002 Aug 27; 59(4):644-5. PMID: 12196672.
    View in: PubMed
  30. Nestoridi E, Buonanno FS, Jones RM, Krishnamoorthy K, Grant PE, Van Cott EM, Grabowski EF. Arterial ischemic stroke in childhood: the role of plasma-phase risk factors. Curr Opin Neurol. 2002 Apr; 15(2):139-44. PMID: 11923626.
    View in: PubMed
  31. Takeoka M, Soman TB, Yoshii A, Caviness VS, Gonzalez RG, Grant PE, Krishnamoorthy KS. Diffusion-weighted images in neonatal cerebral hypoxic-ischemic injury. Pediatr Neurol. 2002 Apr; 26(4):274-81. PMID: 11992754.
    View in: PubMed
  32. Takeoka M, Soman TB, Shih VE, Caviness VS, Krishnamoorthy KS. Carbamyl phosphate synthetase 1 deficiency: a destructive encephalopathy. Pediatr Neurol. 2001 Mar; 24(3):193-9. PMID: 11301219.
    View in: PubMed
  33. Krishnamoorthy KS, Soman TB, Takeoka M, Schaefer PW. Diffusion-weighted imaging in neonatal cerebral infarction: clinical utility and follow-up. J Child Neurol. 2000 Sep; 15(9):592-602. PMID: 11019790.
    View in: PubMed
  34. Bromley B, Krishnamoorthy KS, Benacerraf BR. Aicardi syndrome: prenatal sonographic findings. A report of two cases. Prenat Diagn. 2000 Apr; 20(4):344-6. PMID: 10740210.
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  35. Krishnamoorthy K, Ramu K, Srividya A, Appavoo NC, Saxena NB, Lal S, Das PK. Cost of mass annual single dose diethylcarbamazine distribution for the large scale control of lymphatic filariasis. Indian J Med Res. 2000 Mar; 111:81-9. PMID: 10937383.
    View in: PubMed
  36. Insoft RM, Hurvitz J, Estrella E, Krishnamoorthy KS. Prader-Willi syndrome associated with fetal goiter: a case report. Am J Perinatol. 1999; 16(1):29-31. PMID: 10362079.
    View in: PubMed
  37. Takeoka M, Krishnamoorthy KS, Soman TB, Caviness VS. Fosphenytoin in infants. J Child Neurol. 1998 Nov; 13(11):537-40. PMID: 9853645.
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  38. Kothare SV, Ebb DH, Rosenberger PB, Buonanno F, Schaefer PW, Krishnamoorthy KS. Acute confusion and mutism as a presentation of thalamic strokes secondary to deep cerebral venous thrombosis. J Child Neurol. 1998 Jun; 13(6):300-3. PMID: 9660519.
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  39. Coughlin EM, Christensen E, Kunz PL, Krishnamoorthy KS, Walker V, Dennis NR, Chalmers RA, Elpeleg ON, Whelan D, Pollitt RJ, Ramesh V, Mandell R, Shih VE. Molecular analysis and prenatal diagnosis of human fumarase deficiency. Mol Genet Metab. 1998 Apr; 63(4):254-62. PMID: 9635293.
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  40. Subramanian S, Krishnamoorthy K, Ramaiah KD, Habbema JD, Das PK, Plaisier AP. The relationship between microfilarial load in the human host and uptake and development of Wuchereria bancrofti microfilariae by Culex quinquefasciatus: a study under natural conditions. Parasitology. 1998 Mar; 116 ( Pt 3):243-55. PMID: 9550218.
    View in: PubMed
  41. Rajendran G, Panicker KN, Krishnamoorthy K, Sabesan S, Radhakrishnan R. Current status of filariasis in Chavakad taluk, Trichur district, Kerala. J Commun Dis. 1997 Dec; 29(4):333-43. PMID: 10085639.
    View in: PubMed
  42. Cramer SC, Schaefer PW, Krishnamoorthy KS. Microgyria in the distribution of the middle cerebral artery in a patient with DiGeorge syndrome. J Child Neurol. 1996 Nov; 11(6):494-7. PMID: 9120232.
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  43. Khurana DS, Buonanno F, Ebb D, Krishnamoorthy KS. The role of anticoagulation in idiopathic cerebral venous thrombosis. J Child Neurol. 1996 May; 11(3):248-50. PMID: 8734033.
    View in: PubMed
  44. Eavey RD, Bertero Mdo C, Thornton AR, Herrmann BS, Joseph JM, Gliklich RE, Krishnamoorthy KS, Todres ID. Failure to clinically predict NICU hearing loss. Clin Pediatr (Phila). 1995 Mar; 34(3):138-45. PMID: 7774140.
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  45. Squires LA, Krishnamoorthy KS, Natowicz MR. Delayed myelination in infants and young children: radiographic and clinical correlates. J Child Neurol. 1995 Mar; 10(2):100-4. PMID: 7540191.
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  46. Krishnamoorthy KS. Management of generalized tonic-clonic status epilepticus. Indian J Pediatr. 1994 Jan-Feb; 61(1):43-7. PMID: 7927597.
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  47. Krishnamoorthy KS, Todres DI. Management of cerebral edema and intracranial hypertension. Indian J Pediatr. 1994 Jan-Feb; 61(1):27-32. PMID: 7927595.
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  48. Squires LA, Neumeyer AM, Bloomberg J, Krishnamoorthy KS. Hyperpyrexia in an adolescent on desipramine treatment. Clin Pediatr (Phila). 1992 Oct; 31(10):635-6. PMID: 1395373.
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  49. Sabesan S, Krishnamoorthy K, Panicker KN, Vanamail P. The dynamics of microfilaraemia and its relation with development of disease in periodic Brugia malayi infection in south India. Epidemiol Infect. 1991 Oct; 107(2):453-63. PMID: 1936164; PMCID: PMC2272055.
  50. Panicker KN, Krishnamoorthy K, Sabesan S, Prathiba J. Comparison of effects of mass annual and biannual single dose therapy with diethylcarbamazine for the control of Malayan filariasis. Southeast Asian J Trop Med Public Health. 1991 Sep; 22(3):402-11. PMID: 1818392.
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  51. Srividya A, Krishnamoorthy K, Sabesan S, Panicker KN, Grenfell BT, Bundy DA. Frequency distribution of Brugia malayi microfilariae in human populations. Parasitology. 1991 Apr; 102 Pt 2:207-12. PMID: 1852488.
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  52. Mikati MA, Trevathan E, Krishnamoorthy KS, Lombroso CT. Pyridoxine-dependent epilepsy: EEG investigations and long-term follow-up. Electroencephalogr Clin Neurophysiol. 1991 Mar; 78(3):215-21. PMID: 1707793.
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  53. Leviton A, Pagano M, Kuban KC, Krishnamoorthy KS, Sullivan KF, Allred EN. The epidemiology of germinal matrix hemorrhage during the first half-day of life. Dev Med Child Neurol. 1991 Feb; 33(2):138-45. PMID: 2015981.
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  54. Mikati MA, Feraru E, Krishnamoorthy K, Lombroso CT. Neonatal herpes simplex meningoencephalitis: EEG investigations and clinical correlates. Neurology. 1990 Sep; 40(9):1433-7. PMID: 2392231.
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  55. Krishnamoorthy KS, Kuban KC, Leviton A, Brown ER, Sullivan KF, Allred EN. Periventricular-intraventricular hemorrhage, sonographic localization, phenobarbital, and motor abnormalities in low birth weight infants. Pediatrics. 1990 Jun; 85(6):1027-33. PMID: 2187174.
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  56. Krishnamoorthy KS, Todres ID. Subependymal-intraventricular hemorrhage in the newborn. Indian J Pediatr. 1990 May-Jun; 57(3):313-23. PMID: 2228084.
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  57. Leviton A, Kuban KC, Pagano M, Brown ER, Krishnamoorthy KS, Allred EN. Maternal toxemia and neonatal germinal matrix hemorrhage in intubated infants less than 1751 g. Obstet Gynecol. 1988 Oct; 72(4):571-6. PMID: 3047606.
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  58. Skouteli HN, Kuban KC, Leviton A, Brown ER, Krishnamoorthy KS, Pagano M, Allred EN, Sullivan KF, Baglivo JA, Huff KR, et al. Arterial blood gas derangements associated with death and intracranial hemorrhage in premature babies. J Perinatol. 1988; 8(4):336-41. PMID: 3236103.
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  59. Kuban KC, Leviton A, Brown ER, Krishnamoorthy K, Baglivo J, Sullivan KF, Allred E. Respiratory complications in low-birth-weight infants who received phenobarbital. Am J Dis Child. 1987 Sep; 141(9):996-9. PMID: 3618574.
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  60. Filipek PA, Krishnamoorthy KS, Davis KR, Kuehnle K. Focal cerebral infarction in the newborn: a distinct entity. Pediatr Neurol. 1987 May-Jun; 3(3):141-7. PMID: 3508059.
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  61. Kuban KC, Leviton A, Krishnamoorthy KS, Brown ER, Teele RL, Baglivo JA, Sullivan KF, Huff KR, White S, Cleveland RH, et al. Neonatal intracranial hemorrhage and phenobarbital. Pediatrics. 1986 Apr; 77(4):443-50. PMID: 3515304.
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  62. Mikati MA, Krishnamoorthy KS. Hypoglycorrhachia in neonatal herpes simplex virus meningoencephalitis. J Pediatr. 1985 Nov; 107(5):746-8. PMID: 4056974.
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  63. Krishnamoorthy KS, Kuehnle KJ, Todres ID, DeLong GR. Neurodevelopmental outcome of survivors with posthemorrhagic hydrocephalus following Grade II neonatal intraventricular hemorrhage. Ann Neurol. 1984 Feb; 15(2):201-4. PMID: 6703659.
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  64. Krishnamoorthy KS, Zalneraitis EL, Young RS, Bernad PG. Phenytoin-induced choreoathetosis in infancy: case reports and a review. Pediatrics. 1983 Dec; 72(6):831-4. PMID: 6646926.
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  65. Krishnamoorthy KS. Pyridoxine-dependency seizure: report of a rare presentation. Ann Neurol. 1983 Jan; 13(1):103-4. PMID: 6830153.
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  66. Young RS, Gang DL, Zalneraitis EL, Krishnamoorthy KS. Dysmaturation in infants of mothers with myotonic dystrophy. Arch Neurol. 1981 Nov; 38(11):716-9. PMID: 7305702.
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  67. Kelly DH, Krishnamoorthy KS, Shannon DC. Astrocytoma in an infant with prolonged apnea. Pediatrics. 1980 Sep; 66(3):429-31. PMID: 7422432.
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  68. Zalneraitis EL, Young RS, Krishnamoorthy KS. Intracranial hemorrhage in utero as a complication of isoimmune thrombocytopenia. J Pediatr. 1979 Oct; 95(4):611-4. PMID: 480045.
    View in: PubMed
  69. Krishnamoorthy KS, Shannon DC, DeLong GR, Todres ID, Davis KR. Neurologic sequelae in the survivors of neonatal intraventricular hemorrhage. Pediatrics. 1979 Aug; 64(2):233-7. PMID: 89657.
    View in: PubMed
  70. Krishnamoorthy KS, Fernandez RA, Momose KJ, DeLong GR, Moylan FM, Todres ID, Shannon DC. Evaluation of neonatal intracranial hemorrhage by computerized tomography. Pediatrics. 1977 Feb; 59(2):165-72. PMID: 299937.
    View in: PubMed
  71. Krishnamoorthy KS, Fernandex RJ, Todres ID, De Long GR. Paraplegia associated with umbilical artery catheterization in the newborn. Pediatrics. 1976 Sep; 58(3):443-5. PMID: 958773.
    View in: PubMed
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