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Aaron Bradley Waxman, M.D., Ph.D.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01HL125215 (LEOPOLD, JANE A) Sep 17, 2014 - Jul 31, 2021
    Intergrated Endothelial Phenotyping to Redefine Pulmonary Hypertension
    Role: Co-Principal Investigator
  2. R01HL074859 (WAXMAN, AARON B) Apr 1, 2004 - Feb 29, 2008
    Il-6 type cytokine protection from hyperoxic lung injury
    Role: Principal Investigator
  3. K08HL003888 (WAXMAN, AARON B) Jul 1, 1998 - Jun 30, 2004
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Nathan SD, Tapson VF, Elwing J, Rischard F, Mehta J, Shapiro S, Shen E, Deng C, Smith P, Waxman A. Efficacy of Inhaled Treprostinil on Multiple Disease Progression Events in Patients with Pulmonary Hypertension due to Parenchymal Lung Disease in the INCREASE Trial. Am J Respir Crit Care Med. 2022 01 15; 205(2):198-207. PMID: 34767495.
    Citations: 2     Fields:    Translation:Humans
  2. Dieffenbach PB, Mallarino Haeger C, Rehman R, Corcoran AM, Coronata AMF, Vellarikkal SK, Chrobak I, Waxman AB, Vitali SH, Sholl LM, Padera RF, Lagares D, Polverino F, Owen CA, Fredenburgh LE. A Novel Protective Role for Matrix Metalloproteinase-8 in the Pulmonary Vasculature. Am J Respir Crit Care Med. 2021 12 15; 204(12):1433-1451. PMID: 34550870.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  3. Minhas J, Nardelli P, Hassan SM, Al-Naamani N, Harder E, Ash S, Sánchez-Ferrero GV, Mason S, Hunsaker AR, Piazza G, Goldhaber SZ, Waxman AB, Kawut SM, Estépar RSJ, Washko GR, Rahaghi FN. Loss of Pulmonary Vascular Volume as a Predictor of Right Ventricular Dysfunction and Mortality in Acute Pulmonary Embolism. Circ Cardiovasc Imaging. 2021 09; 14(9):e012347. PMID: 34544259.
    Citations:    Fields:    Translation:Humans
  4. Singh I, Joseph P, Heerdt PM, Cullinan M, Lutchmansingh DD, Gulati M, Possick JD, Systrom DM, Waxman AB. Persistent Exertional Intolerance After COVID-19: Insights From Invasive Cardiopulmonary Exercise Testing. Chest. 2022 01; 161(1):54-63. PMID: 34389297.
    Citations: 7     Fields:    Translation:HumansCells
  5. Rahaghi FN, Nardelli P, Harder E, Singh I, Sánchez-Ferrero GV, Ross JC, San José Estépar R, Ash SY, Hunsaker AR, Maron BA, Leopold JA, Waxman AB, San José Estépar R, Washko GR. Quantification of Arterial and Venous Morphologic Markers in Pulmonary Arterial Hypertension Using CT Imaging. Chest. 2021 12; 160(6):2220-2231. PMID: 34270966.
    Citations: 1     Fields:    Translation:Humans
  6. Nathan SD, Waxman A, Rajagopal S, Case A, Johri S, DuBrock H, De La Zerda DJ, Sahay S, King C, Melendres-Groves L, Smith P, Shen E, Edwards LD, Nelsen A, Tapson VF. Inhaled treprostinil and forced vital capacity in patients with interstitial lung disease and associated pulmonary hypertension: a post-hoc analysis of the INCREASE study. Lancet Respir Med. 2021 11; 9(11):1266-1274. PMID: 34214475.
    Citations: 1     Fields:    Translation:CTClinical Trials
  7. Menon AA, Ruopp NF, Parakh A, Cockrill B, Waxman AB. A Woman with a Repaired Atrial Septal Defect and Pulmonary Hypertension with Worsening Dyspnea. Ann Am Thorac Soc. 2021 06; 18(6):1052-1058. PMID: 34076557.
    Citations:    Fields:    Translation:Humans
  8. Nathan SD, Waxman A, Tapson V. Inhaled Treprostinil in Group 3 Pulmonary Hypertension. Reply. N Engl J Med. 2021 05 13; 384(19):1871-1872. PMID: 33979501.
    Citations:    Fields:    Translation:Humans
  9. Faria-Urbina M, Ung KT, Lawler L, Zisman LS, Waxman AB. Inspiratory flow patterns with dry powder inhalers of low and medium flow resistance in patients with pulmonary arterial hypertension. Pulm Circ. 2021 Apr-Jun; 11(2):20458940211012591. PMID: 34035895.
  10. Rahaghi FN, Hilton JF, Corrêa RA, Loureiro C, Ota-Arakaki JS, Verrastro CGY, Lee MH, Mickael C, Nardelli P, Systrom DA, Waxman AB, Washko GR, San José Estépar R, Graham BB, Oliveira RKF. Arterial vascular volume changes with haemodynamics in schistosomiasis-associated pulmonary arterial hypertension. Eur Respir J. 2021 05; 57(5). PMID: 33446601.
    Citations: 1     Fields:    Translation:Humans
  11. Humbert M, McLaughlin V, Gibbs JSR, Gomberg-Maitland M, Hoeper MM, Preston IR, Souza R, Waxman A, Escribano Subias P, Feldman J, Meyer G, Montani D, Olsson KM, Manimaran S, Barnes J, Linde PG, de Oliveira Pena J, Badesch DB. Sotatercept for the Treatment of Pulmonary Arterial Hypertension. N Engl J Med. 2021 04 01; 384(13):1204-1215. PMID: 33789009.
    Citations: 20     Fields:    Translation:HumansCTClinical Trials
  12. Feldman JP, Gomberg-Maitland M, Shapiro SM, Lautenbach AA, Morris M, Murphy JA, Waxman AB, Bourge RC. Implantable system for treprostinil and lung transplantation: case series from delivery for pulmonary arterial hypertension study. Pulm Circ. 2021 Jan-Mar; 11(1):2045894021999290. PMID: 33738097.
  13. Singh I, Oliveira RKF, Naeije R, Oldham WM, Faria-Urbina M, Waxman AB, Systrom DM. Systemic vascular distensibility relates to exercise capacity in connective tissue disease. Rheumatology (Oxford). 2021 03 02; 60(3):1429-1434. PMID: 33001175.
    Citations: 1     Fields:    Translation:Humans
  14. Waxman AB, Singh I. Pulmonary Hypertension: An Integrative Approach to Assessment and Management. Clin Chest Med. 2021 03; 42(1):xiii-xiv. PMID: 33541622.
    Citations:    Fields:    
  15. Waxman A, Restrepo-Jaramillo R, Thenappan T, Ravichandran A, Engel P, Bajwa A, Allen R, Feldman J, Argula R, Smith P, Rollins K, Deng C, Peterson L, Bell H, Tapson V, Nathan SD. Inhaled Treprostinil in Pulmonary Hypertension Due to Interstitial Lung Disease. N Engl J Med. 2021 01 28; 384(4):325-334. PMID: 33440084.
    Citations: 20     Fields:    Translation:Humans
  16. Singh I, Oliveira RKF, Heerdt PM, Pari R, Systrom DM, Waxman AB. Sex-Related Differences in Dynamic Right Ventricular-Pulmonary Vascular Coupling in Heart Failure With Preserved Ejection Fraction. Chest. 2021 06; 159(6):2402-2416. PMID: 33388286.
    Citations: 1     Fields:    Translation:Humans
  17. Han Y, Forfia P, Vaidya A, Mazurek JA, Park MH, Ramani G, Chan SY, Waxman AB. Ranolazine Improves Right Ventricular Function in Patients With Precapillary Pulmonary Hypertension: Results From a Double-Blind, Randomized, Placebo-Controlled Trial. J Card Fail. 2021 Feb; 27(2):253-257. PMID: 33223140.
    Citations: 6     Fields:    Translation:Humans
  18. Singh I, Oliveira RKF, Heerdt P, Brown MB, Faria-Urbina M, Waxman AB, Systrom DM. Dynamic right ventricular function response to incremental exercise in pulmonary hypertension. Pulm Circ. 2020 Jul-Sep; 10(3):2045894020950187. PMID: 33062259.
    Citations: 2     
  19. Joseph P, Oliveira RKF, Eslam RB, Agarwal M, Waxman AB, Systrom DM. Fick principle and exercise pulmonary hemodynamic determinants of the six-minute walk distance in pulmonary hypertension. Pulm Circ. 2020 Jul-Sep; 10(3):2045894020957576. PMID: 32994925.
  20. Harder EM, Waxman AB. Clinical trials in group 3 pulmonary hypertension. Curr Opin Pulm Med. 2020 09; 26(5):391-396. PMID: 32657833.
    Citations: 2     Fields:    Translation:Humans
  21. Oliveira RKF, Waxman AB, Hoover PJ, Dellaripa PF, Systrom DM. Pulmonary Vascular and Right Ventricular Burden During Exercise in Interstitial Lung Disease. Chest. 2020 07; 158(1):350-358. PMID: 32173491.
    Citations: 2     Fields:    Translation:Humans
  22. Tang WHW, Wilcox JD, Jacob MS, Rosenzweig EB, Borlaug BA, Frantz RP, Hassoun PM, Hemnes AR, Hill NS, Horn EM, Singh HS, Systrom DM, Tedford RJ, Vanderpool RR, Waxman AB, Xiao L, Leopold JA, Rischard FP. Comprehensive Diagnostic Evaluation of Cardiovascular Physiology in Patients With Pulmonary Vascular Disease: Insights From the PVDOMICS Program. Circ Heart Fail. 2020 03; 13(3):e006363. PMID: 32088984.
    Citations: 3     Fields:    Translation:Humans
  23. Samokhin AO, Hsu S, Yu PB, Waxman AB, Alba GA, Wertheim BM, Hopkins CD, Bowman F, Channick RN, Nikolic I, Faria-Urbina M, Hassoun PM, Leopold JA, Tedford RJ, Ventetuolo CE, Leary PJ, Maron BA. Circulating NEDD9 is increased in pulmonary arterial hypertension: A multicenter, retrospective analysis. J Heart Lung Transplant. 2020 04; 39(4):289-299. PMID: 31952977.
    Citations: 7     Fields:    Translation:HumansCells
  24. Gomberg-Maitland M, Bourge RC, Shapiro SM, Tarver JH, Zwicke DL, Feldman JP, Chakinala MM, Frantz RP, Torres F, Bag R, Murphy JA, Lautenbach AA, Morris M, Peterson L, Waxman AB. Long-term results of the DelIVery for Pulmonary Arterial Hypertension trial. Pulm Circ. 2019 Oct-Dec; 9(4):2045894019878615. PMID: 31723407.
    Citations: 5     
  25. Sanders JL, Han Y, Urbina MF, Systrom DM, Waxman AB. Metabolomics of exercise pulmonary hypertension are intermediate between controls and patients with pulmonary arterial hypertension. Pulm Circ. 2019 Oct-Dec; 9(4):2045894019882623. PMID: 31695905.
    Citations: 5     
  26. Melamed KH, Santos M, Oliveira RKF, Urbina MF, Felsenstein D, Opotowsky AR, Waxman AB, Systrom DM. Unexplained exertional intolerance associated with impaired systemic oxygen extraction. Eur J Appl Physiol. 2019 Oct; 119(10):2375-2389. PMID: 31493035.
    Citations: 7     Fields:    Translation:Humans
  27. Singh I, Rahaghi FN, Naeije R, Oliveira RKF, Vanderpool RR, Waxman AB, Systrom DM. Dynamic right ventricular-pulmonary arterial uncoupling during maximum incremental exercise in exercise pulmonary hypertension and pulmonary arterial hypertension. Pulm Circ. 2019 Jul-Sep; 9(3):2045894019862435. PMID: 31218910.
    Citations: 10     
  28. Kohli P, Kelly VJ, Kehl EG, Rodriguez-Lopez J, Hibbert KA, Kone M, Systrom DM, Waxman AB, Venegas JG, Channick R, Winkler T, Harris RS. Perfusion Imaging Distinguishes Exercise Pulmonary Arterial Hypertension at Rest. Am J Respir Crit Care Med. 2019 06 01; 199(11):1438-1441. PMID: 30811948.
    Citations: 3     Fields:    Translation:Humans
  29. Singh I, Oliveira RKF, Naeije R, Rahaghi FN, Oldham WM, Systrom DM, Waxman AB. Pulmonary Vascular Distensibility and Early Pulmonary Vascular Remodeling in Pulmonary Hypertension. Chest. 2019 10; 156(4):724-732. PMID: 31121149.
    Citations: 8     Fields:    Translation:Humans
  30. Singh I, Rahaghi FN, Naeije R, Oliveira RKF, Systrom DM, Waxman AB. Right Ventricular-Arterial Uncoupling During Exercise in Heart Failure With Preserved Ejection Fraction: Role of Pulmonary Vascular Dysfunction. Chest. 2019 11; 156(5):933-943. PMID: 31103695.
    Citations: 9     Fields:    Translation:Humans
  31. Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, Wendell SG, Mullett SJ, Sembrat J, Rojas M, Khan OF, Dahlman JE, Sugahara M, Kagiyama N, Satoh T, Zhang M, Feng N, Gorcsan J, Vargas SO, Haley KJ, Kumar R, Graham BB, Langer R, Anderson DG, Wang B, Shiva S, Bertero T, Chan SY. BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension. Circulation. 2019 05 07; 139(19):2238-2255. PMID: 30759996.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  32. Hahn RT, Waxman AB, Denti P, Delhaas T. Anatomic Relationship of the Complex Tricuspid Valve, Right Ventricle, and Pulmonary Vasculature: A Review. JAMA Cardiol. 2019 05 01; 4(5):478-487. PMID: 30994879.
    Citations: 6     Fields:    Translation:Humans
  33. Hahn RT, Delhaas T, Denti P, Waxman AB. The Tricuspid Valve Relationship With the Right Ventricle and Pulmonary Vasculature. JACC Cardiovasc Imaging. 2019 03; 12(3):564-565. PMID: 30660539.
    Citations: 1     Fields:    Translation:Humans
  34. Platz E, Merz A, Silverman M, Lewis E, Groarke JD, Waxman A, Systrom D. Association between lung ultrasound findings and invasive exercise haemodynamics in patients with undifferentiated dyspnoea. ESC Heart Fail. 2019 02; 6(1):202-207. PMID: 30474936.
    Citations: 4     Fields:    Translation:Humans
  35. Schissler AJ, Gylnn RJ, Sobieszczyk PS, Waxman AB. Ultrasound-assisted catheter-directed thrombolysis compared with anticoagulation alone for treatment of intermediate-risk pulmonary embolism. Pulm Circ. 2018 Oct-Dec; 8(4):2045894018800265. PMID: 30142025.
    Citations: 5     
  36. Samokhin AO, Stephens T, Wertheim BM, Wang RS, Vargas SO, Yung LM, Cao M, Brown M, Arons E, Dieffenbach PB, Fewell JG, Matar M, Bowman FP, Haley KJ, Alba GA, Marino SM, Kumar R, Rosas IO, Waxman AB, Oldham WM, Khanna D, Graham BB, Seo S, Gladyshev VN, Yu PB, Fredenburgh LE, Loscalzo J, Leopold JA, Maron BA. NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension. Sci Transl Med. 2018 06 13; 10(445). PMID: 29899023.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  37. Ryan JJ, Waxman AB. The Dyspnea Clinic. Circulation. 2018 05 08; 137(19):1994-1996. PMID: 29735586.
    Citations: 1     Fields:    Translation:Humans
  38. McCabe C, Oliveira RKF, Rahaghi F, Faria-Urbina M, Howard L, Axell RG, Priest AN, Waxman AB, Systrom DM. Right ventriculo-arterial uncoupling and impaired contractile reserve in obese patients with unexplained exercise intolerance. Eur J Appl Physiol. 2018 Jul; 118(7):1415-1426. PMID: 29713818.
    Citations: 1     Fields:    Translation:Humans
  39. Han Y, Forfia PR, Vaidya A, Mazurek JA, Park MH, Ramani G, Chan SY, Waxman AB. Rationale and design of the ranolazine PH-RV study: a multicentred randomised and placebo-controlled study of ranolazine to improve RV function in patients with non-group 2 pulmonary hypertension. Open Heart. 2018; 5(1):e000736. PMID: 29531764.
    Citations: 5     Fields:    
  40. Oldham WM, Oliveira RKF, Wang RS, Opotowsky AR, Rubins DM, Hainer J, Wertheim BM, Alba GA, Choudhary G, Tornyos A, MacRae CA, Loscalzo J, Leopold JA, Waxman AB, Olschewski H, Kovacs G, Systrom DM, Maron BA. Network Analysis to Risk Stratify Patients With Exercise Intolerance. Circ Res. 2018 03 16; 122(6):864-876. PMID: 29437835.
    Citations: 19     Fields:    Translation:Humans
  41. Faria-Urbina M, Oliveira RKF, Segrera SA, Lawler L, Waxman AB, Systrom DM. Impaired systemic oxygen extraction in treated exercise pulmonary hypertension: a new engine in an old car? Pulm Circ. 2018 Jan-Mar; 8(1):2045893218755325. PMID: 29309261.
    Citations: 3     
  42. Faria-Urbina M, Oliveira RKF, Agarwal M, Waxman AB. Inhaled Treprostinil in Pulmonary Hypertension Associated with Lung Disease. Lung. 2018 04; 196(2):139-146. PMID: 29275453.
    Citations: 2     Fields:    Translation:Humans
  43. Truong QA, Bhatia HS, Szymonifka J, Zhou Q, Lavender Z, Waxman AB, Semigran MJ, Malhotra R. A four-tier classification system of pulmonary artery metrics on computed tomography for the diagnosis and prognosis of pulmonary hypertension. J Cardiovasc Comput Tomogr. 2018 Jan - Feb; 12(1):60-66. PMID: 29254655.
    Citations: 3     Fields:    Translation:Humans
  44. Huang W, Oliveira RKF, Lei H, Systrom DM, Waxman AB. Pulmonary Vascular Resistance During Exercise Predicts Long-Term Outcomes in Heart Failure With Preserved Ejection Fraction. J Card Fail. 2018 Mar; 24(3):169-176. PMID: 29180305.
    Citations: 7     Fields:    Translation:Humans
  45. Roldan T, Villamañán E, Rios JJ, Waxman AB. Assessment of the quality of anticoagulation management in patients with pulmonary arterial hypertension. Thromb Res. 2017 Dec; 160:83-90. PMID: 29127864.
    Citations:    Fields:    Translation:Humans
  46. Hemnes AR, Beck GJ, Newman JH, Abidov A, Aldred MA, Barnard J, Berman Rosenzweig E, Borlaug BA, Chung WK, Comhair SAA, Erzurum SC, Frantz RP, Gray MP, Grunig G, Hassoun PM, Hill NS, Horn EM, Hu B, Lempel JK, Maron BA, Mathai SC, Olman MA, Rischard FP, Systrom DM, Tang WHW, Waxman AB, Xiao L, Yuan JX, Leopold JA. PVDOMICS: A Multi-Center Study to Improve Understanding of Pulmonary Vascular Disease Through Phenomics. Circ Res. 2017 10 27; 121(10):1136-1139. PMID: 29074534.
    Citations: 43     Fields:    Translation:HumansCTClinical Trials
  47. Roldan T, Rios JJ, Villamañan E, Waxman AB. Complications associated with the use of oral anticoagulation in patients with pulmonary arterial hypertension from two referral centers. Pulm Circ. 2017 Jul-Sep; 7(3):692-701. PMID: 28677986.
    Citations: 3     
  48. van Riel ACMJ, Systrom DM, Oliveira RKF, Landzberg MJ, Mulder BJM, Bouma BJ, Maron BA, Shah AM, Waxman AB, Opotowsky AR. Hemodynamic and metabolic characteristics associated with development of a right ventricular outflow tract pressure gradient during upright exercise. PLoS One. 2017; 12(6):e0179053. PMID: 28636647.
    Citations:    Fields:    Translation:Humans
  49. Oliveira RKF, Faria-Urbina M, Maron BA, Santos M, Waxman AB, Systrom DM. Functional impact of exercise pulmonary hypertension in patients with borderline resting pulmonary arterial pressure. Pulm Circ. 2017 Jul-Sep; 7(3):654-665. PMID: 28895507.
    Citations: 12     
  50. Waxman AB, McElderry HT, Gomberg-Maitland M, Burke MC, Ross EL, Bersohn MM, Pangarkar SS, Tarver JH, Zwicke DL, Feldman JP, Chakinala MM, Frantz RP, Thompson GB, Torres F, Rauck RL, Clagg K, Durst L, Li P, Morris M, Southall KL, Peterson L, Bourge RC. Totally Implantable IV Treprostinil Therapy in Pulmonary Hypertension Assessment of the Implantation Procedure. Chest. 2017 12; 152(6):1128-1134. PMID: 28583617.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  51. Huang W, Resch S, Oliveira RK, Cockrill BA, Systrom DM, Waxman AB. Invasive cardiopulmonary exercise testing in the evaluation of unexplained dyspnea: Insights from a multidisciplinary dyspnea center. Eur J Prev Cardiol. 2017 07; 24(11):1190-1199. PMID: 28506086.
    Citations: 11     Fields:    Translation:Humans
  52. Segrera SA, Lawler L, Opotowsky AR, Systrom D, Waxman AB. Open label study of ambrisentan in patients with exercise pulmonary hypertension. Pulm Circ. 2017 Apr-Jun; 7(2):531-538. PMID: 28597763.
    Citations: 8     
  53. Badr Eslam R, Croce K, Mangione FM, Musmann R, Leopold JA, Mitchell RN, Waxman AB. Persistence and proliferation of human mesenchymal stromal cells in the right ventricular myocardium after intracoronary injection in a large animal model of pulmonary hypertension. Cytotherapy. 2017 06; 19(6):668-679. PMID: 28392314.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  54. van Riel AC, Opotowsky AR, Santos M, Rivero JM, Dhimitri A, Mulder BJ, Bouma BJ, Landzberg MJ, Waxman AB, Systrom DM, Shah AM. Accuracy of Echocardiography to Estimate Pulmonary Artery Pressures With Exercise: A Simultaneous Invasive-Noninvasive Comparison. Circ Cardiovasc Imaging. 2017 Apr; 10(4). PMID: 28360262.
    Citations: 16     Fields:    Translation:Humans
  55. van Riel AC, Systrom DM, Oliveira RK, Landzberg MJ, Mulder BJ, Bouma BJ, Maron BA, Shah AM, Waxman AB, Opotowsky AR. Development of a Right Ventricular Outflow Tract Gradient During Upright Exercise: A Hemodynamic Observation. J Am Coll Cardiol. 2017 02 07; 69(5):595-597. PMID: 28153114.
    Citations: 2     Fields:    Translation:Humans
  56. Biering-Sørensen T, Santos M, Rivero J, McCullough SD, West E, Opotowsky AR, Waxman AB, Systrom DM, Shah AM. Left ventricular deformation at rest predicts exercise-induced elevation in pulmonary artery wedge pressure in patients with unexplained dyspnoea. Eur J Heart Fail. 2017 01; 19(1):101-110. PMID: 27878925.
    Citations: 9     Fields:    Translation:Humans
  57. Tikkanen AU, Rhodes J, Landzberg M, Bhatt A, Systrom DM, Waxman A, Moko L, Bradley R, Crouter S, Opotowsky A. Poster 26 A Randomized Trial of Cardiac Rehabilitation for Adolescents and Adults with Congenital Heart Disease. PM R. 2016 Sep; 8(9S):S169. PMID: 27672794.
    Citations: 2     Fields:    
  58. Bertero T, Oldham WM, Cottrill KA, Pisano S, Vanderpool RR, Yu Q, Zhao J, Tai Y, Tang Y, Zhang YY, Rehman S, Sugahara M, Qi Z, Gorcsan J, Vargas SO, Saggar R, Saggar R, Wallace WD, Ross DJ, Haley KJ, Waxman AB, Parikh VN, De Marco T, Hsue PY, Morris A, Simon MA, Norris KA, Gaggioli C, Loscalzo J, Fessel J, Chan SY. Vascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension. J Clin Invest. 2016 09 01; 126(9):3313-35. PMID: 27548520.
    Citations: 160     Fields:    Translation:HumansAnimalsCells
  59. Babu AS, Arena R, Myers J, Padmakumar R, Maiya AG, Cahalin LP, Waxman AB, Lavie CJ. Exercise intolerance in pulmonary hypertension: mechanism, evaluation and clinical implications. Expert Rev Respir Med. 2016 09; 10(9):979-90. PMID: 27192047.
    Citations: 10     Fields:    Translation:Humans
  60. Agarwal M, Waxman AB. Physiological Techniques and Pulmonary Hypertension - Left Heart Disease. Prog Cardiovasc Dis. 2016 Jul-Aug; 59(1):30-41. PMID: 27211586.
    Citations:    Fields:    Translation:Humans
  61. Oliveira RK, Waxman AB, Agarwal M, Badr Eslam R, Systrom DM. Pulmonary haemodynamics during recovery from maximum incremental cycling exercise. Eur Respir J. 2016 07; 48(1):158-67. PMID: 27126692.
    Citations: 11     Fields:    Translation:Humans
  62. Aghamohammadzadeh R, Zhang YY, Stephens TE, Arons E, Zaman P, Polach KJ, Matar M, Yung LM, Yu PB, Bowman FP, Opotowsky AR, Waxman AB, Loscalzo J, Leopold JA, Maron BA. Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertension. FASEB J. 2016 07; 30(7):2511-27. PMID: 27006450.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  63. Oldham WM, Lewis GD, Opotowsky AR, Waxman AB, Systrom DM. Unexplained exertional dyspnea caused by low ventricular filling pressures: results from clinical invasive cardiopulmonary exercise testing. Pulm Circ. 2016 Mar; 6(1):55-62. PMID: 27162614.
    Citations: 21     
  64. Rahaghi FN, Ross JC, Agarwal M, González G, Come CE, Diaz AA, Vegas-Sánchez-Ferrero G, Hunsaker A, San José Estépar R, Waxman AB, Washko GR. Pulmonary vascular morphology as an imaging biomarker in chronic thromboembolic pulmonary hypertension. Pulm Circ. 2016 Mar; 6(1):70-81. PMID: 27162616.
    Citations: 19     
  65. Bourge RC, Waxman AB, Gomberg-Maitland M, Shapiro SM, Tarver JH, Zwicke DL, Feldman JP, Chakinala MM, Frantz RP, Torres F, Cerkvenik J, Morris M, Thalin M, Peterson L, Rubin LJ. Treprostinil Administered to Treat Pulmonary Arterial Hypertension Using a Fully Implantable Programmable Intravascular Delivery System: Results of the DelIVery for PAH Trial. Chest. 2016 Jul; 150(1):27-34. PMID: 27396777.
    Citations: 17     Fields:    Translation:HumansCTClinical Trials
  66. Oliveira RK, Agarwal M, Tracy JA, Karin AL, Opotowsky AR, Waxman AB, Systrom DM. Age-related upper limits of normal for maximum upright exercise pulmonary haemodynamics. Eur Respir J. 2016 Apr; 47(4):1179-88. PMID: 26677941.
    Citations: 28     Fields:    Translation:Humans
  67. Waxman AB, Farber HW. Using Clinical Trial End Points to Risk Stratify Patients With Pulmonary Arterial Hypertension. Circulation. 2015 Dec 01; 132(22):2152-61. PMID: 26621638.
    Citations: 6     Fields:    Translation:Humans
  68. Berry NC, Manyoo A, Oldham WM, Stephens TE, Goldstein RH, Waxman AB, Tracy JA, Leary PJ, Leopold JA, Kinlay S, Opotowsky AR, Systrom DM, Maron BA. Protocol for exercise hemodynamic assessment: performing an invasive cardiopulmonary exercise test in clinical practice. Pulm Circ. 2015 Dec; 5(4):610-8. PMID: 26697168.
    Citations: 20     
  69. Bertero T, Cottrill KA, Lu Y, Haeger CM, Dieffenbach P, Annis S, Hale A, Bhat B, Kaimal V, Zhang YY, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Black SM, Fratz S, Fineman JR, Vargas SO, Haley KJ, Waxman AB, Chau BN, Fredenburgh LE, Chan SY. Matrix Remodeling Promotes Pulmonary Hypertension through Feedback Mechanoactivation of the YAP/TAZ-miR-130/301 Circuit. Cell Rep. 2015 Nov 03; 13(5):1016-32. PMID: 26565914.
    Citations: 106     Fields:    Translation:HumansAnimalsCells
  70. Roldan T, Landzberg MJ, Deicicchi DJ, Atay JK, Waxman AB. Anticoagulation in patients with pulmonary arterial hypertension: An update on current knowledge. J Heart Lung Transplant. 2016 Feb; 35(2):151-64. PMID: 26527532.
    Citations: 11     Fields:    Translation:Humans
  71. Santos M, Rivero J, McCullough SD, West E, Opotowsky AR, Waxman AB, Systrom DM, Shah AM. E/e' Ratio in Patients With Unexplained Dyspnea: Lack of Accuracy in Estimating Left Ventricular Filling Pressure. Circ Heart Fail. 2015 Jul; 8(4):749-56. PMID: 26067855.
    Citations: 34     Fields:    Translation:Humans
  72. White K, Lu Y, Annis S, Hale AE, Chau BN, Dahlman JE, Hemann C, Opotowsky AR, Vargas SO, Rosas I, Perrella MA, Osorio JC, Haley KJ, Graham BB, Kumar R, Saggar R, Saggar R, Wallace WD, Ross DJ, Khan OF, Bader A, Gochuico BR, Matar M, Polach K, Johannessen NM, Prosser HM, Anderson DG, Langer R, Zweier JL, Bindoff LA, Systrom D, Waxman AB, Jin RC, Chan SY. Genetic and hypoxic alterations of the microRNA-210-ISCU1/2 axis promote iron-sulfur deficiency and pulmonary hypertension. EMBO Mol Med. 2015 Jun; 7(6):695-713. PMID: 25825391.
    Citations: 70     Fields:    Translation:HumansAnimalsCells
  73. Riviello ED, Letchford S, Cook EF, Waxman AB, Gaziano T. Improving decision making for massive transfusions in a resource poor setting: a preliminary study in Kenya. PLoS One. 2015; 10(5):e0127987. PMID: 26020935.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  74. Santos M, Opotowsky AR, Shah AM, Tracy J, Waxman AB, Systrom DM. Central cardiac limit to aerobic capacity in patients with exertional pulmonary venous hypertension: implications for heart failure with preserved ejection fraction. Circ Heart Fail. 2015 Mar; 8(2):278-85. PMID: 25550438.
    Citations: 23     Fields:    Translation:Humans
  75. Bertero T, Cottrill K, Krauszman A, Lu Y, Annis S, Hale A, Bhat B, Waxman AB, Chau BN, Kuebler WM, Chan SY. The microRNA-130/301 family controls vasoconstriction in pulmonary hypertension. J Biol Chem. 2015 Jan 23; 290(4):2069-85. PMID: 25505270.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  76. Preston IR, Feldman J, White J, Franco V, Ishizawar D, Burger C, Waxman AB, Hill NS. Safety and efficacy of transition from inhaled treprostinil to parenteral treprostinil in selected patients with pulmonary arterial hypertension. Pulm Circ. 2014 Sep; 4(3):456-61. PMID: 25621159.
    Citations: 6     
  77. Bertero T, Lu Y, Annis S, Hale A, Bhat B, Saggar R, Saggar R, Wallace WD, Ross DJ, Vargas SO, Graham BB, Kumar R, Black SM, Fratz S, Fineman JR, West JD, Haley KJ, Waxman AB, Chau BN, Cottrill KA, Chan SY. Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension. J Clin Invest. 2014 Aug; 124(8):3514-28. PMID: 24960162.
    Citations: 103     Fields:    Translation:HumansAnimalsCells
  78. Frantz RP, Durst L, Burger CD, Oudiz RJ, Bourge RC, Franco V, Waxman AB, McDevitt S, Walker S. Conversion from sildenafil to tadalafil: results from the sildenafil to tadalafil in pulmonary arterial hypertension (SITAR) study. J Cardiovasc Pharmacol Ther. 2014 Nov; 19(6):550-7. PMID: 24742768.
    Citations: 8     Fields:    Translation:Humans
  79. Nakahira K, Kyung SY, Rogers AJ, Gazourian L, Youn S, Massaro AF, Quintana C, Osorio JC, Wang Z, Zhao Y, Lawler LA, Christie JD, Meyer NJ, Mc Causland FR, Waikar SS, Waxman AB, Chung RT, Bueno R, Rosas IO, Fredenburgh LE, Baron RM, Christiani DC, Hunninghake GM, Choi AM. Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation. PLoS Med. 2013 Dec; 10(12):e1001577; discussion e1001577. PMID: 24391478.
    Citations: 180     Fields:    Translation:Humans
  80. Mehra MR, Park MH, Landzberg MJ, Lala A, Waxman AB. Right heart failure: toward a common language. Pulm Circ. 2013 Dec; 3(4):963-7. PMID: 25006413.
    Citations: 5     
  81. Opotowsky AR, Santos M, Maron BA, Afilalo J, Waxman AB, Landzberg MJ, Forfia PR. Towards widespread noninvasive assessment of pulmonary vascular resistance in clinical practice. J Am Soc Echocardiogr. 2014 Jan; 27(1):108-9. PMID: 24280251.
    Citations: 1     Fields:    Translation:Humans
  82. Boerrigter BG, Waxman AB, Westerhof N, Vonk-Noordegraaf A, Systrom DM. Measuring central pulmonary pressures during exercise in COPD: how to cope with respiratory effects. Eur Respir J. 2014 May; 43(5):1316-25. PMID: 24177003.
    Citations: 23     Fields:    Translation:Humans
  83. Mehra MR, Park MH, Landzberg MJ, Lala A, Waxman AB. Right heart failure: toward a common language. J Heart Lung Transplant. 2014 Feb; 33(2):123-6. PMID: 24268184.
    Citations: 18     Fields:    Translation:Humans
  84. Maron BA, Waxman AB, Opotowsky AR, Gillies H, Blair C, Aghamohammadzadeh R, Loscalzo J, Leopold JA. Effectiveness of spironolactone plus ambrisentan for treatment of pulmonary arterial hypertension (from the [ARIES] study 1 and 2 trials). Am J Cardiol. 2013 Sep 01; 112(5):720-5. PMID: 23751938.
    Citations: 34     Fields:    Translation:HumansCTClinical Trials
  85. Opotowsky AR, Clair M, Afilalo J, Landzberg MJ, Waxman AB, Moko L, Maron BA, Vaidya A, Forfia PR. A simple echocardiographic method to estimate pulmonary vascular resistance. Am J Cardiol. 2013 Sep 15; 112(6):873-82. PMID: 23735649.
    Citations: 18     Fields:    Translation:Humans
  86. Maron BA, Cockrill BA, Waxman AB, Systrom DM. The invasive cardiopulmonary exercise test. Circulation. 2013 Mar 12; 127(10):1157-64. PMID: 23479667.
    Citations: 45     Fields:    Translation:Humans
  87. Waxman AB, Zamanian RT. Pulmonary arterial hypertension: new insights into the optimal role of current and emerging prostacyclin therapies. Am J Cardiol. 2013 Mar 04; 111(5 Suppl):1A-16A; quiz 17A-19A. PMID: 23414683.
    Citations: 20     Fields:    Translation:Humans
  88. Esch JJ, Shah PB, Cockrill BA, Farber HW, Landzberg MJ, Mehra MR, Mullen MP, Opotowsky AR, Waxman AB, Lock JE, Marshall AC. Transcatheter Potts shunt creation in patients with severe pulmonary arterial hypertension: initial clinical experience. J Heart Lung Transplant. 2013 Apr; 32(4):381-7. PMID: 23415728.
    Citations: 24     Fields:    Translation:Humans
  89. Waxman AB. Oral prostacyclin therapy for pulmonary arterial hypertension: another step forward. Circulation. 2013 Feb 05; 127(5):563-5. PMID: 23307828.
    Citations: 3     Fields:    Translation:Humans
  90. Cockrill BA, Waxman AB. Phosphodiesterase-5 inhibitors. Handb Exp Pharmacol. 2013; 218:229-55. PMID: 24092343.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  91. Waxman A, Chen SY, Boulanger L, Watson JA, Golden G. Factors associated with adherence to phosphodiesterase type 5 inhibitors for the treatment of pulmonary arterial hypertension. J Med Econ. 2013; 16(2):298-306. PMID: 23216015.
    Citations: 7     Fields:    Translation:Humans
  92. Maron BA, Opotowsky AR, Landzberg MJ, Loscalzo J, Waxman AB, Leopold JA. Plasma aldosterone levels are elevated in patients with pulmonary arterial hypertension in the absence of left ventricular heart failure: a pilot study. Eur J Heart Fail. 2013 Mar; 15(3):277-83. PMID: 23111998.
    Citations: 48     Fields:    Translation:Humans
  93. Waxman AB. Exercise physiology and pulmonary arterial hypertension. Prog Cardiovasc Dis. 2012 Sep-Oct; 55(2):172-9. PMID: 23009913.
    Citations: 10     Fields:    Translation:Humans
  94. Maron BA, Bhatt DL, Nykiel M, Kinlay S, Waxman AB. Protocol for vasoreactivity testing with epoprostenol in pulmonary hypertension. Crit Pathw Cardiol. 2012 Mar; 11(1):40-2. PMID: 22337220.
    Citations: 3     Fields:    Translation:Humans
  95. Parikh VN, Jin RC, Rabello S, Gulbahce N, White K, Hale A, Cottrill KA, Shaik RS, Waxman AB, Zhang YY, Maron BA, Hartner JC, Fujiwara Y, Orkin SH, Haley KJ, Barabási AL, Loscalzo J, Chan SY. MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach. Circulation. 2012 Mar 27; 125(12):1520-32. PMID: 22371328.
    Citations: 128     Fields:    Translation:HumansAnimalsCells
  96. Waxman AB. Pulmonary hypertension in heart failure with preserved ejection fraction: a target for therapy? Circulation. 2011 Jul 12; 124(2):133-5. PMID: 21747065.
    Citations: 3     Fields:    Translation:Humans
  97. Malhotra R, Hess D, Lewis GD, Bloch KD, Waxman AB, Semigran MJ. Vasoreactivity to inhaled nitric oxide with oxygen predicts long-term survival in pulmonary arterial hypertension. Pulm Circ. 2011 Apr; 1(2):250-258. PMID: 22020367.
    Citations: 17     
  98. Schlichting DE, Waxman AB, O'Brien LA, Wang T, Naum CC, Rubeiz GJ, Um SL, Williams M, Yan SC. Circulating endothelial and endothelial progenitor cells in patients with severe sepsis. Microvasc Res. 2011 Mar; 81(2):216-21. PMID: 21130783.
    Citations: 8     Fields:    Translation:HumansCells
  99. Kolliputi N, Shaik RS, Waxman AB. The inflammasome mediates hyperoxia-induced alveolar cell permeability. J Immunol. 2010 May 15; 184(10):5819-26. PMID: 20375306.
    Citations: 48     Fields:    Translation:AnimalsCells
  100. Thibault HB, Kurtz B, Raher MJ, Shaik RS, Waxman A, Derumeaux G, Halpern EF, Bloch KD, Scherrer-Crosbie M. Noninvasive assessment of murine pulmonary arterial pressure: validation and application to models of pulmonary hypertension. Circ Cardiovasc Imaging. 2010 Mar; 3(2):157-63. PMID: 20044514.
    Citations: 80     Fields:    Translation:Animals
  101. Troy PJ, Waxman AB. Portopulmonary hypertension: challenges in diagnosis and management. Therap Adv Gastroenterol. 2009 Sep; 2(5):281-6. PMID: 21180556.
    Citations: 1     
  102. Kolliputi N, Waxman AB. IL-6 cytoprotection in hyperoxic acute lung injury occurs via PI3K/Akt-mediated Bax phosphorylation. Am J Physiol Lung Cell Mol Physiol. 2009 Jul; 297(1):L6-16. PMID: 19376889.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  103. Waxman AB, Kolliputi N. IL-6 protects against hyperoxia-induced mitochondrial damage via Bcl-2-induced Bak interactions with mitofusins. Am J Respir Cell Mol Biol. 2009 Oct; 41(4):385-96. PMID: 19168699.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  104. Steiner MK, Syrkina OL, Kolliputi N, Mark EJ, Hales CA, Waxman AB. Interleukin-6 overexpression induces pulmonary hypertension. Circ Res. 2009 Jan 30; 104(2):236-44, 28p following 244. PMID: 19074475.
    Citations: 239     Fields:    Translation:AnimalsCells
  105. Lee PS, Patel SR, Christiani DC, Bajwa E, Stossel TP, Waxman AB. Plasma gelsolin depletion and circulating actin in sepsis: a pilot study. PLoS One. 2008; 3(11):e3712. PMID: 19002257.
    Citations: 26     Fields:    Translation:Humans
  106. Tolle JJ, Waxman AB, Van Horn TL, Pappagianopoulos PP, Systrom DM. Exercise-induced pulmonary arterial hypertension. Circulation. 2008 Nov 18; 118(21):2183-9. PMID: 18981305.
    Citations: 78     Fields:    Translation:Humans
  107. Waxman AB, Lawler L, Cornett G. Cicletanine for the treatment of pulmonary arterial hypertension. Arch Intern Med. 2008 Oct 27; 168(19):2164-6. PMID: 18955648.
    Citations: 3     Fields:    Translation:Humans
  108. Robertson TE, Mann HJ, Hyzy R, Rogers A, Douglas I, Waxman AB, Weinert C, Alapat P, Guntupalli KK, Buchman TG. Multicenter implementation of a consensus-developed, evidence-based, spontaneous breathing trial protocol. Crit Care Med. 2008 Oct; 36(10):2753-62. PMID: 18828193.
    Citations: 11     Fields:    Translation:Humans
  109. Kolliputi N, Waxman AB. IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1-induced apoptosis signal-regulating kinase-1 degradation. Am J Respir Cell Mol Biol. 2009 Mar; 40(3):314-24. PMID: 18776134.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  110. Chetty A, Cao GJ, Manzo N, Nielsen HC, Waxman A. The role of IL-6 and IL-11 in hyperoxic injury in developing lung. Pediatr Pulmonol. 2008 Mar; 43(3):297-304. PMID: 18214944.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  111. Tolle J, Waxman A, Systrom D. Impaired systemic oxygen extraction at maximum exercise in pulmonary hypertension. Med Sci Sports Exerc. 2008 Jan; 40(1):3-8. PMID: 18091026.
    Citations: 20     Fields:    Translation:HumansCells
  112. LaRaia AV, Waxman AB. Pulmonary arterial hypertension: evaluation and management. South Med J. 2007 Apr; 100(4):393-9. PMID: 17458400.
    Citations: 4     Fields:    Translation:Humans
  113. Lee PS, Waxman AB, Cotich KL, Chung SW, Perrella MA, Stossel TP. Plasma gelsolin is a marker and therapeutic agent in animal sepsis. Crit Care Med. 2007 Mar; 35(3):849-55. PMID: 17205019.
    Citations: 47     Fields:    Translation:AnimalsCells
  114. Waxman AB. A review of sitaxsentan sodium in patients with pulmonary arterial hypertension. Vasc Health Risk Manag. 2007; 3(1):151-7. PMID: 17583185.
    Citations: 2     Fields:    Translation:Humans
  115. Steiner MK, Preston IR, Klinger JR, Criner GJ, Waxman AB, Farber HW, Hill NS. Conversion to bosentan from prostacyclin infusion therapy in pulmonary arterial hypertension: a pilot study. Chest. 2006 Nov; 130(5):1471-80. PMID: 17099026.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  116. Barker GF, Manzo ND, Cotich KL, Shone RK, Waxman AB. DNA damage induced by hyperoxia: quantitation and correlation with lung injury. Am J Respir Cell Mol Biol. 2006 Sep; 35(3):277-88. PMID: 16574945.
    Citations: 37     Fields:    Translation:AnimalsCells
  117. Lee PS, Waxman A. The importance of differentiating gelsolin isoforms. Am J Respir Crit Care Med. 2006 Mar 15; 173(6):685; author reply 685. PMID: 16522767.
    Citations: 1     Fields:    Translation:HumansAnimals
  118. Garcia-Carbonero R, Supko JG, Maki RG, Manola J, Ryan DP, Harmon D, Puchalski TA, Goss G, Seiden MV, Waxman A, Quigley MT, Lopez T, Sancho MA, Jimeno J, Guzman C, Demetri GD. Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter phase II and pharmacokinetic study. J Clin Oncol. 2005 Aug 20; 23(24):5484-92. PMID: 16110008.
    Citations: 51     Fields:    Translation:HumansCTClinical Trials
  119. Waxman AB, Ward N, Thompson T, Lilly CM, Lisbon A, Hill N, Nasraway SA, Heard S, Corwin H, Levy M. Roundtable debate: Controversies in the management of the septic patient--desperately seeking consensus. Crit Care. 2005 Aug 20; 9(1):E1. PMID: 15693960.
    Citations: 2     Fields:    Translation:Humans
  120. Chetty A, Manzo N, Waxman AB, Nielsen HC. Modulation of IGF-binding protein-2 and -3 in hyperoxic injury in developing rat lung. Pediatr Res. 2005 Aug; 58(2):222-8. PMID: 16055936.
    Citations: 4     Fields:    Translation:AnimalsCells
  121. He CH, Waxman AB, Lee CG, Link H, Rabach ME, Ma B, Chen Q, Zhu Z, Zhong M, Nakayama K, Nakayama KI, Homer R, Elias JA. Bcl-2-related protein A1 is an endogenous and cytokine-stimulated mediator of cytoprotection in hyperoxic acute lung injury. J Clin Invest. 2005 Apr; 115(4):1039-48. PMID: 15841185.
    Citations: 44     Fields:    Translation:AnimalsCells
  122. Thomson LE, Goodman MP, Naqvi TZ, Feldman R, Buchbinder NA, Waxman A, D'Agnolo A. Aortic root infection in a prosthetic valve demonstrated by gallium-67 citrate SPECT. Clin Nucl Med. 2005 Apr; 30(4):265-8. PMID: 15764887.
    Citations: 5     Fields:    Translation:Humans
  123. He CH, Waxman AB, Lee CG, Zhu Z, Chen Q, Elias JA,. Activation In Vivo And In Vitro And TRAIL, Fas, FAS-L, Bid, Bim, BAK And PKC-8 Gene Expression In Vivo. American Journal of Respiratory and Critical Care Medicine in press. 2004.
  124. Barker GF, Manzo N, Salzman AL, Szabo C, Waxman AB,. Inhibition Prolongs Survival in Oxidant-Mediated Lung Injury. American Journal of respiratory and Critical Care Medicine in press. 2004.
  125. Boyce PD, Waxman AB. Pulmonary hypertension: work in progress. J Nucl Cardiol. 2003 Jul-Aug; 10(4):413-23. PMID: 12900746.
    Citations:    Fields:    Translation:Humans
  126. Waxman AB, Shepard JA, Mark EJ. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 14-2003. A 73-year-old woman with pneumonia and progressive respiratory failure. N Engl J Med. 2003 May 08; 348(19):1902-12. PMID: 12736284.
    Citations: 1     Fields:    Translation:Humans
  127. Waxman AB, Mahboubi K, Knickelbein RG, Mantell LL, Manzo N, Pober JS, Elias JA. Interleukin-11 and interleukin-6 protect cultured human endothelial cells from H2O2-induced cell death. Am J Respir Cell Mol Biol. 2003 Oct; 29(4):513-22. PMID: 12730073.
    Citations: 34     Fields:    Translation:HumansCells
  128. Waxman AB,. Invited Commentary on "Tidal Volume Increases Do Not Affect Alveolar Mechanics in Normal Lung But Cause Alveolar Overdistension And Exacerbate Alveolar Instability After Surfactant Deactivation.". Journal Club of the Assembly on Critical Care of the American Thoracic Society. 2003; (February).
  129. He CH, Waxman AB, Ma B, Lee CG, Zhu Z, Wang X, Chen Q, Elias JA,. the Bc1-2-Related A1 Protein Is An Endogenous And Cytokine-Stimulated Mediator Of Cytoprotection In Hyperoxic Acute Lung Injury. American Journal of respiratory and Critical Care Medicine. 2003; 167(7):A428.
  130. Manzo ND, Waxman AB. Pathogenesis of Acute Lung Injury: Experimental Studies. Acute Respiratory Distress Syndrome, Editor Michael Matthay. 2003; 179(Chapter 6):115-146.
  131. Boyce P, Waxman AB,. Pulmonary Hypertension: Work in Progress. Journal of Nuclear Cardiology. 2003; 10(4):413-423.
  132. Papa J, Sasidhar M, Waxman AB,. Hemodynamic Impact of Mechanical Ventilation in ARDS. Clinical Pulmonary Medicine. 2003; 10(3):154-161.
  133. Waxman AB, Shepart JAO, Mark EJ, . Case Records of the Massachusetts General Hospital Case 14-2003-A 73 Year Old Woman with Pneumonia and Progressive Respiratory Failure. New England Journal of Medicine. 2003; 348:1902-12.
  134. Waxman AB,. Invited commentary on "Noninvasive Ventilation during Persistent Weaning Fauilure; A Randomized Controlled Trial.". Journal Club of the Assembly on Critical care of the American Thoracic Society. 2003.
  135. Waxman AB, Manzo N, Li W,. Ad-Bc1-2 Mediated Overexpression Protects From Hyperoxic Lung Injury. American Journal of Respiratory and Critical Care Medicine. 2003; 167(7):A165.
  136. Budhiraja R, Waxman AB,. Pulmonary Hypertension: Diagnosis and Management. Resident and Staff Physician. 2002; 48(9):12-20.
  137. He CH, Waxman AB, Ma B, Lee CG, Zhu Z, Wang X, Chen Q, Elias JA,. The Bcl-2-Related A1 Gene Is Regulated In Vivo And In Vitro. American Journal of respiratory and Critical Care Medicine. 2002; 165(4).
  138. Waxman AB,. Invited commentary on "Prevention of Ventilator-associated Pneumonia by Oral Decontamination. A Prospective, Randomized, Double blind, Placebo-controlled Study.". Journal Club of the Assembly on Critical Care of the American Thoracic Society. 2002; (September).
  139. Waxman AB,. Invited Commentary on "Oscillations and Noise, Inherent Instability of Pressure Support Ventilation?". Journal Club of the Assembly on Critical Care of the American Thoracic Society. 2002; (February).
  140. Waxman AB. Pulmonary function test abnormalities in pulmonary vascular disease and chronic heart failure. Clin Chest Med. 2001 Dec; 22(4):751-8. PMID: 11787662.
    Citations: 4     Fields:    Translation:Humans
  141. Buse K, Waxman A. Public-private health partnerships: a strategy for WHO. Bull World Health Organ. 2001; 79(8):748-54. PMID: 11545332.
    Citations: 31     Fields:    Translation:Humans
  142. Waxman AB,. Pulmonary Function Testing in Pulmonary Vascular Disease and Chronic Heart Disease. Clinics in Chest Medicine, Pulmonary Function Testing. 2001; 22(4):751-758.
  143. Seithi J, Waxman AB,. Cellular and Molecular Mechanisms of Lung Injury and Repair. Clinical Pulmonary Medicine. 2001; 8(4):214-225.
  144. McArdle JR, Mantell L, Waxman AB, Du Y, Radzano P, Elias JA,. Vascular Endothelial Cell Growth Factor (VEGF) Confers Cytoprotection on Endothelial Cells in Vitro. American Journal of Respiratory and critical Care Medicine. 2001; 163(5).
  145. Waxman AB, . Invited Commentary on "The comfort of breathing: A study with volunteers assessing the influence of various modes of assisted ventillation. Journal Club of the Assembly on Critical Care of American Thoracic Society. 2001; (January).
  146. Corne J, Chupp G, Lee CG, Homer RJ, Zhu Z, Chen Q, Ma B, Du Y, Roux F, McArdle J, Waxman AB, Elias JA. IL-13 stimulates vascular endothelial cell growth factor and protects against hyperoxic acute lung injury. J Clin Invest. 2000 Sep; 106(6):783-91. PMID: 10995789.
    Citations: 59     Fields:    Translation:AnimalsCells
  147. Ward NS, Waxman AB, Homer RJ, Mantell LL, Einarsson O, Du Y, Elias JA. Interleukin-6-induced protection in hyperoxic acute lung injury. Am J Respir Cell Mol Biol. 2000 May; 22(5):535-42. PMID: 10783124.
    Citations: 80     Fields:    Translation:AnimalsCells
  148. Corne J, Waxman AB, Elias JA,. Cc-10 Interleukin-13 (IL-13) Transgenic Mice Exhibit Enhanced Protection From Hyperoxic Lung Injury. American Journal of Respiratory and Critical Care Medicine. 2000; 164(4).
  149. Corne J, Waxman AB, Elias JA,. Vascular Endothelial Growth Factor (VEGF) But NOt Keratinocyte Growth Factor (KGF) Is Upregulated in Cc-10IL-13 Transgenic Mice Exposed To Hyperoxia. American Journal of Respiratory and Critical Care Medicine. 2000; 161(4).
  150. Waxman AB, Reilly MA, Du Y, Elias JA,. Cc-10IL-11 and Cc-10-IL-6 Overexpression Transgenic Mice Are Protected From Oxidant Mediated Cell Death Via Divergent Anti-Death Pathways. American Journal of Respiratory and Critical Care Medicine. 2000; 161(4).
  151. Waxman AB, . Invited commentary on "Prospective randomized trial comparing pressure-controlled ventilation and volume-controlled ventilation in ARDS.". Journal Club of the Assembly on Critical Care of American Thoracic Society. 2000; (July).
  152. Waxman AB, Du Y, Elias JA. IL-11 Protects Endothelial Cells From Oxidant Medicated Cell Death. American Journal of Respiratory and Critical Care Medicine. 2000; 161(4).
  153. Ward NS, Waxman AB, Einarsson O, Elias JA. Interleukin-6 protection in hyperoxic lung injury. Chest. 1999 Jul; 116(1 Suppl):26S. PMID: 10424569.
    Citations: 2     Fields:    Translation:Animals
  154. Waxman AB, Einarsson O, Seres T, Knickelbein RG, Homer R, Warshaw JB, Johnston R, Elias JA. Targeted lung expression of interleukin-11 enhances murine tolerance of 100% oxygen and diminishes hyperoxia-induced DNA fragmentation. Chest. 1999 Jul; 116(1 Suppl):8S-9S. PMID: 10424559.
    Citations: 8     Fields:    Translation:Animals
  155. Lin HC, Van Citters GW, Zhao XT, Waxman A. Fat intolerance depends on rapid gastric emptying. Dig Dis Sci. 1999 Feb; 44(2):330-5. PMID: 10063919.
    Citations: 9     Fields:    Translation:Humans
  156. Waxman AB, Sasidhar M,. Practical Use of the Pulmonary Artery Catheter in the ICU. Journal of Respiratory Diseases. 1999; 20(June):106-118.
  157. Ward NS, Waxman AB, Mantell L, Du Y, Elias JA,. Interleukin-6 protection in hyperoxic lung injury. Association with diminished apotosis and increased Bcl-2. American Journal of Respiratory and Critical Care Medicine. 1999; 157(4).
  158. Waxman AB, Einarsson O, Seres T, Knickelbein RG, Warshaw JB, Johnston R, Homer RJ, Elias JA. Targeted lung expression of interleukin-11 enhances murine tolerance of 100% oxygen and diminishes hyperoxia-induced DNA fragmentation. J Clin Invest. 1998 May 01; 101(9):1970-82. PMID: 9576762.
    Citations: 50     Fields:    Translation:AnimalsCells
  159. Ward NS, Waxman AB, Einarsson O, Elias JA,. IL-6 protection in hyperoxic lung injury. Plenary Presentation at the Connecticut Thoracic Society Regional Spring Scientific Session, Meriden, CT. 1998.
  160. Waxman AB, Einarsson O, Seres T, Knickelbein RG, Homer R, Warshaw JB, Johnston R, Elias JA,. Elias Targeted lung expression of interleukin-11 enhances murine tolerance of 100% oxygen and diminishes hyperoxia-induced DNA fragmentation. Plenary Presentation at the Thomas L. Petty Aspen Lung Conference, Aspen Colorado (June 3-6). Chest. 1998; 115.
  161. Waxman AB, Matthay M,. Critical Review of Pulmonary Artery Catheter Use in the ICU. Pulmonary and Critical Care Update. 1998; 12(21).
  162. Siegel M, Waxman AB,. Acute Respiratory Distress Syndrome. Advanced Therapy in Thoracic Surgery (K. Franco and J.B. Putnam, eds). 1998; 1-13.
  163. Waxman AB, Du Y, Elias JA,. Interleukin-11 protection in hyperoxic lung injury. Association with diminished apoptosis and increased Bcl-2. American Journal of Respiratory and Critical Care Medicine. 1998; 157(4).
  164. Waxman AB, White KP, Trawick DR. Electromechanical dissociation following verapamil and propranolol ingestion: a physiologic profile. Cardiology. 1997 Sep-Oct; 88(5):478-81. PMID: 9286512.
    Citations: 1     Fields:    Translation:Humans
  165. Waxman AB, Goldie SJ, Brett-Smith H, Matthay RA. Cytomegalovirus as a primary pulmonary pathogen in AIDS. Chest. 1997 Jan; 111(1):128-34. PMID: 8996006.
    Citations: 8     Fields:    Translation:HumansCells
  166. Waxman AB, Seres T, Knickelbein RG, Warshaw JB, Elias JA,. IL-11 induced tolerance to 100% oxygen: Role of endogenous antioxidants. American Journal of Respiratory and Critical Care Medicine. 1997; 154(4).
  167. Waxman AB, Ray P, Elias JA. Lung specific inducible expression of interleukin-11 in transgenic mice exhibit enhanced tolerance to 100% oxygen. Chest. 1997; 112(3S):47.
  168. Waxman AB, Matthay RA,. A 51 Year Old woman with a bone marrow transplant and rapidly progressive Dyspnea. Critical Care Pearls. Second Edition, (S.A. Sahn and J.E. Heffner, eds). 1997; 254-256.
  169. Waxman AB, einarsson O, Elias JA, . CC-10-IL-11 Transgenic Mice Exhibit Enhanced Tolerance to 100% Oxygen. Plenary Presentation at the Connecticut Thoracic Society Regional Spring Scientific Session, Meriden CT. 1996.
  170. Waxman AB, Einarsson O, Elias JA,. CC-10-IL-11 transgenic Mice Exhibit Enhanced Tolerance to 100% Oxygen. American Journal of Respiratory and Critical Care Medicine. 1996; 153(4).
  171. Elias JA, Tang WL, Geba GP, Zheng T, Ray P, Wang P, Waxman AB, Einarsson O,. Airway Fibrosis and Enhanced Oxygen Tolerance in IL-11 Overexpression Transgenic Mice. Presented at the 8th International Colloquium on Pulmonary Fibrosis, Oaxaca City, Mexico (11/10-13/1996). 1996.
  172. Waxman AB,. Cytomegalovirus as a Primary Pulmonary Pathogen in AIDS. Plenary presentation at the Connecticut Chapter of the American College of Physicians Regional Spring Scientific Session, Farmington, CT. 1994.
  173. Rosen G, Loren GJ, Brien EW, Ramana L, Waxman A, Lowenbraun S, Eckardt JJ, Eilber F, Menendez L, Mirra JM. Serial thallium-201 scintigraphy in osteosarcoma. Correlation with tumor necrosis after preoperative chemotherapy. Clin Orthop Relat Res. 1993 Aug; (293):302-6. PMID: 8393392.
    Citations: 6     Fields:    Translation:Humans
  174. Ramanna L, Waxman A, Braunstein G. Thallium-201 scintigraphy in differentiated thyroid cancer: comparison with radioiodine scintigraphy and serum thyroglobulin determinations. J Nucl Med. 1991 Mar; 32(3):441-6. PMID: 2005453.
    Citations: 3     Fields:    Translation:Humans
  175. Ramanna L, Waxman A, Binney G, Waxman S, Mirra J, Rosen G. Thallium-201 scintigraphy in bone sarcoma: comparison with gallium-67 and technetium-MDP in the evaluation of chemotherapeutic response. J Nucl Med. 1990 May; 31(5):567-72. PMID: 2341892.
    Citations: 20     Fields:    Translation:Humans
  176. Friedman J, Van Train K, Maddahi J, Rozanski A, Prigent F, Bietendorf J, Waxman A, Berman DS. "Upward creep" of the heart: a frequent source of false-positive reversible defects during thallium-201 stress-redistribution SPECT. J Nucl Med. 1989 Oct; 30(10):1718-22. PMID: 2795212.
    Citations: 50     Fields:    Translation:Humans
  177. Rodrigues EA, Maddahi J, Brown H, Pantaleo N, Freeman M, Koerner S, Waxman A, Berman DS. Responses of left and right ventricular ejection fractions to aerobic and anaerobic phases of upright and supine exercise in normal subjects. Am Heart J. 1989 Aug; 118(2):319-24. PMID: 2750653.
    Citations: 4     Fields:    Translation:Humans
  178. Waxman AB, Cooper M, Smith SJ,. Spontaneous intracellular calcium fluctuations occur in neurons of the Embryonic Hippocampus. Society of Neuroscience. 1989; 15.
  179. Smith SJ, Forscher P, Cooper M, Waxman AB,. Developmental events in living neurons and nervious systems. Electron Microscopy Society of America. 1989; 47.
  180. Cooper M, Waxman AB, Banker GA,. Live observation of dynamic events in the formation of cerebral cortex by laser microscopy. Society of Neuroscience . 1989; 15.
  181. Connelly J, Waxman AB, Klemm WR,. The Pig Brain in Stereotaxic Coordinates. 1989.
  182. Smith SJ, Cooper MW, Waxman AB,. Laser Microscopy of Subcellular Structure in Living Neocortex: Can One See Dendritic Spices Twitch?. Proceedings of 23rd Symposium Medicum Hoechst on "The Biology of Memory", Eds. L. Squire and E. Lindenlaub. 1989; 237-256.
  183. Friedman J, Berman DS, Van Train K, Garcia EV, Bietendorf J, Prigent F, Rozanski A, Waxman A, Maddahi J. Patient motion in thallium-201 myocardial SPECT imaging. An easily identified frequent source of artifactual defect. Clin Nucl Med. 1988 May; 13(5):321-4. PMID: 3260547.
    Citations: 16     Fields:    Translation:Humans
  184. Higgins D, Waxman A, Banker G. The distribution of microtubule-associated protein 2 changes when dendritic growth is induced in rat sympathetic neurons in vitro. Neuroscience. 1988 Feb; 24(2):583-92. PMID: 3362354.
    Citations: 1     Fields:    Translation:AnimalsCells
  185. Banker GA, Waxman AB, Klemm WR,. Hippocampal neurons generate natural shapes in cell culture. Intrinsic Determinants of Neuronal Form. (R. Lasek and M.B. Black, eds.). 1988; 128-140.
  186. Waxman AB,. The Role of Cell Interactions in the Development of Dendritic Arbors of Hippocampal Neurons in Culture. Doctoral Thesis. 1988.
  187. Weiss AT, Berman DS, Lew AS, Nielsen J, Potkin B, Swan HJ, Waxman A, Maddahi J. Transient ischemic dilation of the left ventricle on stress thallium-201 scintigraphy: a marker of severe and extensive coronary artery disease. J Am Coll Cardiol. 1987 Apr; 9(4):752-9. PMID: 3558976.
    Citations: 71     Fields:    Translation:Humans
  188. Waxman AB, Banker GA,. An analysis of the role of cell contact in the development of dendritic. Society for Neuroscience. 1987; 13.
  189. Mohsenifar Z, Ross MD, Waxman A, Goldbach P, Koerner SK. Changes in distribution of lung perfusion and ventilation at rest and during maximal exercise. Chest. 1985 Mar; 87(3):359-62. PMID: 3971762.
    Citations: 3     Fields:    Translation:Humans
  190. Waxman AB, Banker GA,. An analysis of the dentritic form of hippocampal neurons in dissociated-cell culture grown at different densities. Society for Neuroscience. 1985; 11.
  191. Waxman AB, Banker GA,. An analysis of the dendritic form of hippocampal neurons in dissociated-cell culture. The Anatomical Record. 1985; 211(No 3).
  192. Gutman J, Berman DS, Freeman M, Rozanski A, Maddahi J, Waxman A, Swan HJ. Time to completed redistribution of thallium-201 in exercise myocardial scintigraphy: relationship to the degree of coronary artery stenosis. Am Heart J. 1983 Nov; 106(5 Pt 1):989-95. PMID: 6637782.
    Citations: 25     Fields:    Translation:Humans
  193. Gutman J, Brachman M, Rozanski A, Maddahi J, Waxman A, Berman DS. Enhanced detection of proximal right coronary artery stenosis with the additional analysis of right ventricular thallium-201 uptake in stress scintigrams. Am J Cardiol. 1983 May 01; 51(8):1256-60. PMID: 6846153.
    Citations: 1     Fields:    Translation:Humans
  194. Maddahi J, Garcia EV, Berman DS, Waxman A, Swan HJ, Forrester J. Improved noninvasive assessment of coronary artery disease by quantitative analysis of regional stress myocardial distribution and washout of thallium-201. Circulation. 1981 Nov; 64(5):924-35. PMID: 7285307.
    Citations: 36     Fields:    Translation:Humans
  195. Elkayam U, Weinstein M, Berman D, Maddahi J, Staniloff H, Freeman M, Waxman A, Swan HJ, Forrester J. Stress thallium-201 myocardial scintigraphy and exercise technetium ventriculography in the detection and location of chronic coronary artery disease: comparison of sensitivity and specificity of these noninvasive tests alone and in combination. Am Heart J. 1981 May; 101(5):657-66. PMID: 7223605.
    Citations: 6     Fields:    Translation:Humans
  196. Gray R, Maddahi J, Berman D, Raymond M, Waxman A, Ganz W, Matloff J, Swan HJ. Scintigraphic and hemodynamic demonstration of transient left ventricular dysfunction immediately after uncomplicated coronary artery bypass grafting. J Thorac Cardiovasc Surg. 1979 Apr; 77(4):504-10. PMID: 311395.
    Citations: 10     Fields:    Translation:Humans
  197. Hollander CS, Scott RL, Tschudy DP, Perlroth M, Waxman A, Sterling K. Increased protein-bound iodine and thyroxine-binding globulin in acute intermittent porphyria. N Engl J Med. 1967 Nov 09; 277(19):995-1000. PMID: 4168454.
    Citations: 5     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.