Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Dai Fukumura, Ph.D., M.D.

Co-Author

This page shows the publications co-authored by Dai Fukumura and Rakesh Jain.
Connection Strength

28.292
  1. Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges. Nat Rev Clin Oncol. 2018 05; 15(5):325-340.
    View in: PubMed
    Score: 0.791
  2. Obesity and Cancer: An Angiogenic and Inflammatory Link. Microcirculation. 2016 Apr; 23(3):191-206.
    View in: PubMed
    Score: 0.692
  3. Measuring interstitial pH and pO2 in mouse tumors. Cold Spring Harb Protoc. 2013 Jul 01; 2013(7):675-7.
    View in: PubMed
    Score: 0.572
  4. Measuring interstitial diffusion, convection, and binding parameters in mouse tumors. Cold Spring Harb Protoc. 2013 Jul 01; 2013(7):678-80.
    View in: PubMed
    Score: 0.572
  5. Measuring leukocyte-endothelial interactions in mice. Cold Spring Harb Protoc. 2013 Jun 01; 2013(6):561-3.
    View in: PubMed
    Score: 0.568
  6. Measuring vascular permeability in mice. Cold Spring Harb Protoc. 2013 May 01; 2013(5):444-6.
    View in: PubMed
    Score: 0.565
  7. Measuring angiogenesis and hemodynamics in mice. Cold Spring Harb Protoc. 2013 Apr 01; 2013(4):354-8.
    View in: PubMed
    Score: 0.562
  8. Lung window preparation in mice. Cold Spring Harb Protoc. 2013 Jan 01; 2013(1).
    View in: PubMed
    Score: 0.552
  9. Pancreatic tumor preparation in mice. Cold Spring Harb Protoc. 2012 Dec 01; 2012(12).
    View in: PubMed
    Score: 0.549
  10. Liver tumor preparation in mice. Cold Spring Harb Protoc. 2012 Dec 01; 2012(12).
    View in: PubMed
    Score: 0.549
  11. Lymphangiography of the mouse tail. Cold Spring Harb Protoc. 2012 Nov 01; 2012(11):1177-8.
    View in: PubMed
    Score: 0.546
  12. Lymphangiography of the mouse ear. Cold Spring Harb Protoc. 2012 Nov 01; 2012(11):1179-80.
    View in: PubMed
    Score: 0.546
  13. Mammary fat pad chamber preparation in mice. Cold Spring Harb Protoc. 2012 Oct 01; 2012(10):1113-4.
    View in: PubMed
    Score: 0.543
  14. Mammary fat pad tumor preparation in mice. Cold Spring Harb Protoc. 2012 Oct 01; 2012(10):1115-6.
    View in: PubMed
    Score: 0.543
  15. Corneal pocket assay in rabbits. Cold Spring Harb Protoc. 2012 Sep 01; 2012(9):1017-8.
    View in: PubMed
    Score: 0.540
  16. Rabbit ear chambers. Cold Spring Harb Protoc. 2012 Jul 01; 2012(7):813-14.
    View in: PubMed
    Score: 0.533
  17. Tumor microvasculature and microenvironment: novel insights through intravital imaging in pre-clinical models. Microcirculation. 2010 Apr; 17(3):206-25.
    View in: PubMed
    Score: 0.456
  18. Imaging angiogenesis and the microenvironment. APMIS. 2008 Jul-Aug; 116(7-8):695-715.
    View in: PubMed
    Score: 0.404
  19. Targeting PDGF signaling in carcinoma-associated fibroblasts controls cervical cancer in mouse model. PLoS Med. 2008 Jan 29; 5(1):e24.
    View in: PubMed
    Score: 0.393
  20. Tumor microenvironment abnormalities: causes, consequences, and strategies to normalize. J Cell Biochem. 2007 Jul 01; 101(4):937-49.
    View in: PubMed
    Score: 0.377
  21. Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization. Microvasc Res. 2007 Sep-Nov; 74(2-3):72-84.
    View in: PubMed
    Score: 0.374
  22. The role of nitric oxide in tumour progression. Nat Rev Cancer. 2006 Jul; 6(7):521-34.
    View in: PubMed
    Score: 0.352
  23. Engineering vascularized tissue. Nat Biotechnol. 2005 Jul; 23(7):821-3.
    View in: PubMed
    Score: 0.328
  24. Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis. Circ Res. 2003 Oct 31; 93(9):e88-97.
    View in: PubMed
    Score: 0.291
  25. Dissecting tumour pathophysiology using intravital microscopy. Nat Rev Cancer. 2002 Apr; 2(4):266-76.
    View in: PubMed
    Score: 0.262
  26. Hypoxia and acidosis independently up-regulate vascular endothelial growth factor transcription in brain tumors in vivo. Cancer Res. 2001 Aug 15; 61(16):6020-4.
    View in: PubMed
    Score: 0.251
  27. Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas. Nat Commun. 2021 05 11; 12(1):2582.
    View in: PubMed
    Score: 0.246
  28. Exercise Training Improves Tumor Control by Increasing CD8+ T-cell Infiltration via CXCR3 Signaling and Sensitizes Breast Cancer to Immune Checkpoint Blockade. Cancer Immunol Res. 2021 Jul; 9(7):765-778.
    View in: PubMed
    Score: 0.245
  29. Implications of a granulocyte-high glioblastoma microenvironment in immune suppression and therapy resistance†. J Pathol. 2021 Jun; 254(2):105-108.
    View in: PubMed
    Score: 0.244
  30. Predominant role of endothelial nitric oxide synthase in vascular endothelial growth factor-induced angiogenesis and vascular permeability. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2604-9.
    View in: PubMed
    Score: 0.243
  31. Experimental and computational analyses reveal dynamics of tumor vessel cooption and optimal treatment strategies. Proc Natl Acad Sci U S A. 2019 02 12; 116(7):2662-2671.
    View in: PubMed
    Score: 0.210
  32. Dual endothelin receptor inhibition enhances T-DM1 efficacy in brain metastases from HER2-positive breast cancer. NPJ Breast Cancer. 2019; 5:4.
    View in: PubMed
    Score: 0.210
  33. Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium. Nat Biomed Eng. 2019 03; 3(3):230-245.
    View in: PubMed
    Score: 0.210
  34. Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood-tumor barrier disruption. Proc Natl Acad Sci U S A. 2018 09 11; 115(37):E8717-E8726.
    View in: PubMed
    Score: 0.204
  35. Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2. Sci Transl Med. 2018 03 14; 10(432).
    View in: PubMed
    Score: 0.198
  36. Role of nitric oxide in angiogenesis and microcirculation in tumors. Cancer Metastasis Rev. 1998 Mar; 17(1):77-89.
    View in: PubMed
    Score: 0.197
  37. A cerebellar window for intravital imaging of normal and disease states in mice. Nat Protoc. 2017 Nov; 12(11):2251-2262.
    View in: PubMed
    Score: 0.192
  38. Targeting CXCR4-dependent immunosuppressive Ly6Clow monocytes improves antiangiogenic therapy in colorectal cancer. Proc Natl Acad Sci U S A. 2017 09 26; 114(39):10455-10460.
    View in: PubMed
    Score: 0.191
  39. Effect of host microenvironment on the microcirculation of human colon adenocarcinoma. Am J Pathol. 1997 Sep; 151(3):679-88.
    View in: PubMed
    Score: 0.191
  40. Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy. J Clin Invest. 2017 Aug 01; 127(8):3039-3051.
    View in: PubMed
    Score: 0.189
  41. The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation. Sci Transl Med. 2017 05 24; 9(391).
    View in: PubMed
    Score: 0.187
  42. Role of nitric oxide in tumor microcirculation. Blood flow, vascular permeability, and leukocyte-endothelial interactions. Am J Pathol. 1997 Feb; 150(2):713-25.
    View in: PubMed
    Score: 0.183
  43. Corrigendum: Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity. Cold Spring Harb Perspect Med. 2016 12 01; 6(12).
    View in: PubMed
    Score: 0.181
  44. Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity. Cold Spring Harb Perspect Med. 2016 Dec 01; 6(12).
    View in: PubMed
    Score: 0.181
  45. Solid stress and elastic energy as measures of tumour mechanopathology. Nat Biomed Eng. 2016; 1.
    View in: PubMed
    Score: 0.181
  46. Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases. Sci Transl Med. 2016 10 12; 8(360):360ra135.
    View in: PubMed
    Score: 0.179
  47. Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy. Cancer Discov. 2016 08; 6(8):852-69.
    View in: PubMed
    Score: 0.175
  48. Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages. Proc Natl Acad Sci U S A. 2016 Apr 19; 113(16):4470-5.
    View in: PubMed
    Score: 0.173
  49. Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival. Proc Natl Acad Sci U S A. 2016 Apr 19; 113(16):4476-81.
    View in: PubMed
    Score: 0.173
  50. PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity. Clin Cancer Res. 2016 06 15; 22(12):2993-3004.
    View in: PubMed
    Score: 0.171
  51. Mast Cells Contribute to Radiation-Induced Vascular Hyperpermeability. Radiat Res. 2016 Feb; 185(2):182-9.
    View in: PubMed
    Score: 0.170
  52. Metformin Reduces Desmoplasia in Pancreatic Cancer by Reprogramming Stellate Cells and Tumor-Associated Macrophages. PLoS One. 2015; 10(12):e0141392.
    View in: PubMed
    Score: 0.169
  53. Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment. J Natl Cancer Inst. 2016 Feb; 108(2).
    View in: PubMed
    Score: 0.168
  54. Tumor necrosis factor alpha-induced leukocyte adhesion in normal and tumor vessels: effect of tumor type, transplantation site, and host strain. Cancer Res. 1995 Nov 01; 55(21):4824-9.
    View in: PubMed
    Score: 0.168
  55. Vascular diseases await translation of blood vessels engineered from stem cells. Sci Transl Med. 2015 Oct 14; 7(309):309rv6.
    View in: PubMed
    Score: 0.167
  56. From the Guest Editors: Role of Tumor Microenvironment in Tumor Progression and Treatment Response: A 30 Years' Journey. Cancer J. 2015 Jul-Aug; 21(4):235-6.
    View in: PubMed
    Score: 0.164
  57. Lessons From 30 Years of Teaching About the Microenvironment of Tumors. Cancer J. 2015 May-Jun; 21(3):137.
    View in: PubMed
    Score: 0.162
  58. Blockade of MMP14 activity in murine breast carcinomas: implications for macrophages, vessels, and radiotherapy. J Natl Cancer Inst. 2015 Apr; 107(4).
    View in: PubMed
    Score: 0.160
  59. Towards Optimal Design of Cancer Nanomedicines: Multi-stage Nanoparticles for the Treatment of Solid Tumors. Ann Biomed Eng. 2015 Sep; 43(9):2291-300.
    View in: PubMed
    Score: 0.160
  60. Emerging strategies for treating brain metastases from breast cancer. Cancer Cell. 2015 Feb 09; 27(2):163-75.
    View in: PubMed
    Score: 0.160
  61. Benefits of vascular normalization are dose and time dependent--letter. Cancer Res. 2013 Dec 01; 73(23):7144-6.
    View in: PubMed
    Score: 0.147
  62. Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progression. J Natl Cancer Inst. 2013 Aug 21; 105(16):1188-201.
    View in: PubMed
    Score: 0.144
  63. Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells. Proc Natl Acad Sci U S A. 2013 Jul 30; 110(31):12774-9.
    View in: PubMed
    Score: 0.143
  64. Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell. 2013 Feb 28; 152(5):1065-76.
    View in: PubMed
    Score: 0.140
  65. Vascular normalization as an emerging strategy to enhance cancer immunotherapy. Cancer Res. 2013 May 15; 73(10):2943-8.
    View in: PubMed
    Score: 0.140
  66. Combined targeting of HER2 and VEGFR2 for effective treatment of HER2-amplified breast cancer brain metastases. Proc Natl Acad Sci U S A. 2012 Nov 06; 109(45):E3119-27.
    View in: PubMed
    Score: 0.136
  67. Cationic nanoparticles have superior transvascular flux into solid tumors: insights from a mathematical model. Ann Biomed Eng. 2013 Jan; 41(1):68-77.
    View in: PubMed
    Score: 0.134
  68. Normalization of the tumor vasculature through oncogenic inhibition: an emerging paradigm in tumor biology. Proc Natl Acad Sci U S A. 2012 May 15; 109(20):E1214.
    View in: PubMed
    Score: 0.132
  69. Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner. Nat Nanotechnol. 2012 Apr 08; 7(6):383-8.
    View in: PubMed
    Score: 0.131
  70. A transient parabiosis skin transplantation model in mice. Nat Protoc. 2012 Mar 22; 7(4):763-70.
    View in: PubMed
    Score: 0.131
  71. An isolated tumor perfusion model in mice. Nat Protoc. 2012 Mar 22; 7(4):749-55.
    View in: PubMed
    Score: 0.131
  72. Multistage nanoparticles for improved delivery into tumor tissue. Methods Enzymol. 2012; 508:109-30.
    View in: PubMed
    Score: 0.129
  73. Video-rate resonant scanning multiphoton microscopy: An emerging technique for intravital imaging of the tumor microenvironment. Intravital. 2012; 1(1).
    View in: PubMed
    Score: 0.129
  74. Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration. Angew Chem Int Ed Engl. 2011 Nov 25; 50(48):11417-20.
    View in: PubMed
    Score: 0.127
  75. Normalization of the vasculature for treatment of cancer and other diseases. Physiol Rev. 2011 Jul; 91(3):1071-121.
    View in: PubMed
    Score: 0.124
  76. Spontaneous nonthymic tumors in SCID mice. Comp Med. 2011 Jun; 61(3):227-34.
    View in: PubMed
    Score: 0.124
  77. The biology of brain metastases-translation to new therapies. Nat Rev Clin Oncol. 2011 Jun; 8(6):344-56.
    View in: PubMed
    Score: 0.123
  78. CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies? Clin Cancer Res. 2011 Apr 15; 17(8):2074-80.
    View in: PubMed
    Score: 0.121
  79. Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation. Proc Natl Acad Sci U S A. 2011 Mar 01; 108(9):3725-30.
    View in: PubMed
    Score: 0.121
  80. Multistage nanoparticle delivery system for deep penetration into tumor tissue. Proc Natl Acad Sci U S A. 2011 Feb 08; 108(6):2426-31.
    View in: PubMed
    Score: 0.121
  81. Scaling rules for diffusive drug delivery in tumor and normal tissues. Proc Natl Acad Sci U S A. 2011 Feb 01; 108(5):1799-803.
    View in: PubMed
    Score: 0.120
  82. C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells. Proc Natl Acad Sci U S A. 2011 Jan 04; 108(1):302-7.
    View in: PubMed
    Score: 0.120
  83. Malignant cells facilitate lung metastasis by bringing their own soil. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21677-82.
    View in: PubMed
    Score: 0.119
  84. Diffusion of particles in the extracellular matrix: the effect of repulsive electrostatic interactions. Biophys J. 2010 Sep 08; 99(5):1342-9.
    View in: PubMed
    Score: 0.118
  85. In vivo imaging of tumors. Cold Spring Harb Protoc. 2010 Jul 01; 2010(7):pdb.prot5452.
    View in: PubMed
    Score: 0.116
  86. Angiopoietin-2 interferes with anti-VEGFR2-induced vessel normalization and survival benefit in mice bearing gliomas. Clin Cancer Res. 2010 Jul 15; 16(14):3618-27.
    View in: PubMed
    Score: 0.115
  87. Optical methods in vascular biology and medicine. J Biomed Opt. 2010 Jan-Feb; 15(1):011001.
    View in: PubMed
    Score: 0.112
  88. Secreted Gaussia luciferase as a biomarker for monitoring tumor progression and treatment response of systemic metastases. PLoS One. 2009 Dec 15; 4(12):e8316.
    View in: PubMed
    Score: 0.112
  89. VEGFR1 activity modulates myeloid cell infiltration in growing lung metastases but is not required for spontaneous metastasis formation. PLoS One. 2009 Sep 18; 4(9):e6525.
    View in: PubMed
    Score: 0.110
  90. VEGFR1-activity-independent metastasis formation. Nature. 2009 Sep 17; 461(7262):E4; discussion E5.
    View in: PubMed
    Score: 0.110
  91. Paradoxical effects of PDGF-BB overexpression in endothelial cells on engineered blood vessels in vivo. Am J Pathol. 2009 Jul; 175(1):294-302.
    View in: PubMed
    Score: 0.108
  92. Lack of lymphatic vessel phenotype in LYVE-1/CD44 double knockout mice. J Cell Physiol. 2009 May; 219(2):430-7.
    View in: PubMed
    Score: 0.107
  93. Blockade of VEGFR2 and not VEGFR1 can limit diet-induced fat tissue expansion: role of local versus bone marrow-derived endothelial cells. PLoS One. 2009; 4(3):e4974.
    View in: PubMed
    Score: 0.106
  94. Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice. J Clin Oncol. 2009 May 20; 27(15):2542-52.
    View in: PubMed
    Score: 0.106
  95. Endothelial nitric oxide synthase mediates lymphangiogenesis and lymphatic metastasis. Cancer Res. 2009 Apr 01; 69(7):2801-8.
    View in: PubMed
    Score: 0.106
  96. A mathematical model of murine metabolic regulation by leptin: energy balance and defense of a stable body weight. Cell Metab. 2009 Jan 07; 9(1):52-63.
    View in: PubMed
    Score: 0.105
  97. Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and VEGFR-3 kinase inhibitors cediranib and vandetanib. . 2008 Aug; 7(8):2272-9.
    View in: PubMed
    Score: 0.102
  98. Histopathologic findings and establishment of novel tumor lines from spontaneous tumors in FVB/N mice. Comp Med. 2008 Jun; 58(3):253-63.
    View in: PubMed
    Score: 0.100
  99. Perivascular nitric oxide gradients normalize tumor vasculature. Nat Med. 2008 Mar; 14(3):255-7.
    View in: PubMed
    Score: 0.098
  100. Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculature. Blood. 2008 May 01; 111(9):4551-8.
    View in: PubMed
    Score: 0.098
  101. Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels. Blood. 2008 Feb 01; 111(3):1302-5.
    View in: PubMed
    Score: 0.097
  102. Anti-VEGFR-3 therapy and lymph node metastasis [corrected]. Cancer Res. 2007 May 15; 67(10):5055; author reply 5056.
    View in: PubMed
    Score: 0.093
  103. Small blood vessel engineering. Methods Mol Med. 2007; 140:183-95.
    View in: PubMed
    Score: 0.091
  104. Imaging steps of lymphatic metastasis reveals that vascular endothelial growth factor-C increases metastasis by increasing delivery of cancer cells to lymph nodes: therapeutic implications. Cancer Res. 2006 Aug 15; 66(16):8065-75.
    View in: PubMed
    Score: 0.089
  105. Evolution of oxygen and glucose concentration profiles in a tissue-mimetic culture system of embryonic stem cells. Ann Biomed Eng. 2006 Aug; 34(8):1247-58.
    View in: PubMed
    Score: 0.088
  106. Placenta growth factor overexpression inhibits tumor growth, angiogenesis, and metastasis by depleting vascular endothelial growth factor homodimers in orthotopic mouse models. Cancer Res. 2006 Apr 15; 66(8):3971-7.
    View in: PubMed
    Score: 0.087
  107. Onset of abnormal blood and lymphatic vessel function and interstitial hypertension in early stages of carcinogenesis. Cancer Res. 2006 Apr 01; 66(7):3360-4.
    View in: PubMed
    Score: 0.086
  108. Evidence for incorporation of bone marrow-derived endothelial cells into perfused blood vessels in tumors. Blood. 2006 Apr 01; 107(7):2774-6.
    View in: PubMed
    Score: 0.085
  109. Molecular regulation of microlymphatic formation and function: role of nitric oxide. Trends Cardiovasc Med. 2005 Jul; 15(5):169-73.
    View in: PubMed
    Score: 0.082
  110. NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas and tissue-engineered blood vessels. J Clin Invest. 2005 Jul; 115(7):1816-27.
    View in: PubMed
    Score: 0.082
  111. Green fluorescent protein (GFP)-expressing tumor model derived from a spontaneous osteosarcoma in a vascular endothelial growth factor (VEGF)-GFP transgenic mouse. Comp Med. 2005 Jun; 55(3):236-43.
    View in: PubMed
    Score: 0.082
  112. Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo. Nat Med. 2005 Jun; 11(6):678-82.
    View in: PubMed
    Score: 0.081
  113. Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases. Cancer Cell. 2004 Dec; 6(6):553-63.
    View in: PubMed
    Score: 0.079
  114. Differential transplantability of tumor-associated stromal cells. Cancer Res. 2004 Sep 01; 64(17):5920-4.
    View in: PubMed
    Score: 0.077
  115. Peritumor lymphatics induced by vascular endothelial growth factor-C exhibit abnormal function. Cancer Res. 2004 Jul 01; 64(13):4400-4.
    View in: PubMed
    Score: 0.077
  116. Endothelial nitric oxide synthase regulates microlymphatic flow via collecting lymphatics. Circ Res. 2004 Jul 23; 95(2):204-9.
    View in: PubMed
    Score: 0.076
  117. Role of eNOS in neovascularization: NO for endothelial progenitor cells. Trends Mol Med. 2004 Apr; 10(4):143-5.
    View in: PubMed
    Score: 0.075
  118. Influence of the site of human gallbladder xenograft (Mz-ChA-1) on angiogenesis at the distant site. Oncol Rep. 2004 Apr; 11(4):803-7.
    View in: PubMed
    Score: 0.075
  119. Tissue engineering: creation of long-lasting blood vessels. Nature. 2004 Mar 11; 428(6979):138-9.
    View in: PubMed
    Score: 0.075
  120. Sparse initial entrapment of systemically injected Salmonella typhimurium leads to heterogeneous accumulation within tumors. Cancer Res. 2003 Sep 01; 63(17):5188-93.
    View in: PubMed
    Score: 0.072
  121. Photodynamic therapy for cancer. Nat Rev Cancer. 2003 May; 3(5):380-7.
    View in: PubMed
    Score: 0.071
  122. Targeting tumor vasculature and cancer cells in orthotopic breast tumor by fractionated photosensitizer dosing photodynamic therapy. Cancer Res. 2002 Aug 01; 62(15):4289-94.
    View in: PubMed
    Score: 0.067
  123. Vascular accumulation of a novel photosensitizer, MV6401, causes selective thrombosis in tumor vessels after photodynamic therapy. Cancer Res. 2002 Apr 01; 62(7):2151-6.
    View in: PubMed
    Score: 0.066
  124. Role of host microenvironment in angiogenesis and microvascular functions in human breast cancer xenografts: mammary fat pad versus cranial tumors. Clin Cancer Res. 2002 Apr; 8(4):1008-13.
    View in: PubMed
    Score: 0.066
  125. Tumour biology: herceptin acts as an anti-angiogenic cocktail. Nature. 2002 Mar 21; 416(6878):279-80.
    View in: PubMed
    Score: 0.065
  126. Acidic extracellular pH induces vascular endothelial growth factor (VEGF) in human glioblastoma cells via ERK1/2 MAPK signaling pathway: mechanism of low pH-induced VEGF. J Biol Chem. 2002 Mar 29; 277(13):11368-74.
    View in: PubMed
    Score: 0.064
  127. Pancreas microenvironment promotes VEGF expression and tumor growth: novel window models for pancreatic tumor angiogenesis and microcirculation. Lab Invest. 2001 Oct; 81(10):1439-51.
    View in: PubMed
    Score: 0.063
  128. In vivo measurement of gene expression, angiogenesis and physiological function in tumors using multiphoton laser scanning microscopy. Nat Med. 2001 Jul; 7(7):864-8.
    View in: PubMed
    Score: 0.062
  129. FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS. Nat Cancer. 2021 Apr; 2(4):414-428.
    View in: PubMed
    Score: 0.061
  130. Vascular endothelial growth factor (VEGF)-C differentially affects tumor vascular function and leukocyte recruitment: role of VEGF-receptor 2 and host VEGF-A. Cancer Res. 2001 Mar 15; 61(6):2404-8.
    View in: PubMed
    Score: 0.061
  131. Combining losartan with radiotherapy increases tumor control and inhibits lung metastases from a HER2/neu-positive orthotopic breast cancer model. Radiat Oncol. 2021 Mar 04; 16(1):48.
    View in: PubMed
    Score: 0.061
  132. Vascular endothelial growth factor (VEGF) modulation by targeting hypoxia-inducible factor-1alpha--> hypoxia response element--> VEGF cascade differentially regulates vascular response and growth rate in tumors. Cancer Res. 2000 Nov 15; 60(22):6248-52.
    View in: PubMed
    Score: 0.060
  133. NAD+-mediated rescue of prenatal forebrain angiogenesis restores postnatal behavior. Sci Adv. 2020 Oct; 6(41).
    View in: PubMed
    Score: 0.059
  134. Tumor oxygenation in hormone-dependent tumors during vascular endothelial growth factor receptor-2 blockade, hormone ablation, and chemotherapy. Cancer Res. 2000 Aug 15; 60(16):4556-60.
    View in: PubMed
    Score: 0.059
  135. Brain Metastasis Cell Lines Panel: A Public Resource of Organotropic Cell Lines. Cancer Res. 2020 10 15; 80(20):4314-4323.
    View in: PubMed
    Score: 0.058
  136. Irradiation of a primary tumor, unlike surgical removal, enhances angiogenesis suppression at a distal site: potential role of host-tumor interaction. Cancer Res. 2000 Apr 15; 60(8):2128-31.
    View in: PubMed
    Score: 0.057
  137. Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy. Nat Biotechnol. 2020 04; 38(4):420-425.
    View in: PubMed
    Score: 0.056
  138. Cells shed from tumours show reduced clonogenicity, resistance to apoptosis, and in vivo tumorigenicity. Br J Cancer. 1999 Nov; 81(5):756-9.
    View in: PubMed
    Score: 0.055
  139. Tumor-host interactions in the gallbladder suppress distal angiogenesis and tumor growth: involvement of transforming growth factor beta1. Nat Med. 1999 Oct; 5(10):1203-8.
    View in: PubMed
    Score: 0.055
  140. Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. Cancer Res. 1999 Aug 15; 59(16):4129-35.
    View in: PubMed
    Score: 0.055
  141. Retraction Note: A homing system targets therapeutic T cells to brain cancer. Nature. 2019 03; 567(7746):132.
    View in: PubMed
    Score: 0.053
  142. In vitro and in vivo quantification of adhesion between leukocytes and vascular endothelium. Methods Mol Med. 1999; 18:553-75.
    View in: PubMed
    Score: 0.052
  143. Tumor induction of VEGF promoter activity in stromal cells. Cell. 1998 Sep 18; 94(6):715-25.
    View in: PubMed
    Score: 0.051
  144. A homing system targets therapeutic T cells to brain cancer. Nature. 2018 09; 561(7723):331-337.
    View in: PubMed
    Score: 0.051
  145. Consensus guidelines for the use and interpretation of angiogenesis assays. Angiogenesis. 2018 08; 21(3):425-532.
    View in: PubMed
    Score: 0.051
  146. Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice. J Invest Dermatol. 1998 Jul; 111(1):1-6.
    View in: PubMed
    Score: 0.051
  147. Shortwave infrared fluorescence imaging with the clinically approved near-infrared dye indocyanine green. Proc Natl Acad Sci U S A. 2018 04 24; 115(17):4465-4470.
    View in: PubMed
    Score: 0.050
  148. Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity. J Immunol. 2018 04 15; 200(8):3000-3007.
    View in: PubMed
    Score: 0.049
  149. MicroRNA-378 enhances radiation response in ectopic and orthotopic implantation models of glioblastoma. J Neurooncol. 2018 Jan; 136(1):63-71.
    View in: PubMed
    Score: 0.048
  150. Wide-field three-photon excitation in biological samples. Light Sci Appl. 2017 May 05; 6:e16255.
    View in: PubMed
    Score: 0.047
  151. Next-generation in vivo optical imaging with short-wave infrared quantum dots. Nat Biomed Eng. 2017; 1.
    View in: PubMed
    Score: 0.046
  152. Leukocyte-endothelial adhesion and angiogenesis in tumors. Cancer Metastasis Rev. 1996 Jun; 15(2):195-204.
    View in: PubMed
    Score: 0.044
  153. A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer. Sci Transl Med. 2016 Jan 06; 8(320):320ra4.
    View in: PubMed
    Score: 0.043
  154. Mouse embryonic fibroblasts exhibit extensive developmental and phenotypic diversity. Proc Natl Acad Sci U S A. 2016 Jan 05; 113(1):122-7.
    View in: PubMed
    Score: 0.042
  155. Vascular permeability in a human tumor xenograft: molecular size dependence and cutoff size. Cancer Res. 1995 Sep 01; 55(17):3752-6.
    View in: PubMed
    Score: 0.042
  156. Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors. J Am Chem Soc. 2015 Aug 12; 137(31):9832-42.
    View in: PubMed
    Score: 0.041
  157. Quantum dot/antibody conjugates for in vivo cytometric imaging in mice. Proc Natl Acad Sci U S A. 2015 Feb 03; 112(5):1350-5.
    View in: PubMed
    Score: 0.040
  158. Correlative intravital imaging of cGMP signals and vasodilation in mice. Front Physiol. 2014; 5:394.
    View in: PubMed
    Score: 0.039
  159. Magneto-fluorescent core-shell supernanoparticles. Nat Commun. 2014 Oct 09; 5:5093.
    View in: PubMed
    Score: 0.039
  160. Transgenic mice for cGMP imaging. Circ Res. 2013 Aug 02; 113(4):365-71.
    View in: PubMed
    Score: 0.036
  161. Compact high-quality CdSe-CdS core-shell nanocrystals with narrow emission linewidths and suppressed blinking. Nat Mater. 2013 May; 12(5):445-51.
    View in: PubMed
    Score: 0.035
  162. Spatial charge configuration regulates nanoparticle transport and binding behavior in vivo. Angew Chem Int Ed Engl. 2013 Jan 28; 52(5):1414-9.
    View in: PubMed
    Score: 0.034
  163. Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17561-6.
    View in: PubMed
    Score: 0.034
  164. Cancer imaging by optical coherence tomography: preclinical progress and clinical potential. Nat Rev Cancer. 2012 Apr 05; 12(5):363-8.
    View in: PubMed
    Score: 0.033
  165. Studying primary tumor-associated fibroblast involvement in cancer metastasis in mice. Nat Protoc. 2012 Mar 22; 7(4):756-62.
    View in: PubMed
    Score: 0.033
  166. Impaired lymphatic contraction associated with immunosuppression. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):18784-9.
    View in: PubMed
    Score: 0.032
  167. Engineered blood vessel networks connect to host vasculature via wrapping-and-tapping anastomosis. Blood. 2011 Oct 27; 118(17):4740-9.
    View in: PubMed
    Score: 0.031
  168. PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer. Clin Cancer Res. 2011 Jun 01; 17(11):3638-48.
    View in: PubMed
    Score: 0.031
  169. A nanoparticle size series for in vivo fluorescence imaging. Angew Chem Int Ed Engl. 2010 Nov 08; 49(46):8649-52.
    View in: PubMed
    Score: 0.030
  170. Simultaneous measurement of RBC velocity, flux, hematocrit and shear rate in vascular networks. Nat Methods. 2010 Aug; 7(8):655-60.
    View in: PubMed
    Score: 0.029
  171. In vivo wide-area cellular imaging by side-view endomicroscopy. Nat Methods. 2010 Apr; 7(4):303-5.
    View in: PubMed
    Score: 0.028
  172. InAs(ZnCdS) quantum dots optimized for biological imaging in the near-infrared. J Am Chem Soc. 2010 Jan 20; 132(2):470-1.
    View in: PubMed
    Score: 0.028
  173. Compact biocompatible quantum dots via RAFT-mediated synthesis of imidazole-based random copolymer ligand. J Am Chem Soc. 2010 Jan 20; 132(2):472-83.
    View in: PubMed
    Score: 0.028
  174. Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging. Nat Med. 2009 Oct; 15(10):1219-23.
    View in: PubMed
    Score: 0.027
  175. Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast. Opt Lett. 2009 Jul 01; 34(13):2066-8.
    View in: PubMed
    Score: 0.027
  176. Endothelial cells derived from human embryonic stem cells form durable blood vessels in vivo. Nat Biotechnol. 2007 Mar; 25(3):317-8.
    View in: PubMed
    Score: 0.023
  177. Genetic evidence for a tumor suppressor role of HIF-2alpha. Cancer Cell. 2005 Aug; 8(2):131-41.
    View in: PubMed
    Score: 0.021
  178. Responses to antiangiogenesis treatment of spontaneous autochthonous tumors and their isografts. Cancer Res. 2003 Feb 15; 63(4):747-51.
    View in: PubMed
    Score: 0.017
  179. Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors. Cancer Res. 2002 Dec 01; 62(23):6831-6.
    View in: PubMed
    Score: 0.017
  180. Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis. Nature. 1998 Jul 30; 394(6692):485-90.
    View in: PubMed
    Score: 0.013
  181. Mice lacking E-selectin show normal numbers of rolling leukocytes but reduced leukocyte stable arrest on cytokine-activated microvascular endothelium. Microcirculation. 1998; 5(2-3):153-71.
    View in: PubMed
    Score: 0.012
  182. Hyperplasia of lymphatic vessels in VEGF-C transgenic mice. Science. 1997 May 30; 276(5317):1423-5.
    View in: PubMed
    Score: 0.012
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.