Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Dai Fukumura, Ph.D., M.D.

Co-Author

This page shows the publications co-authored by Dai Fukumura and Dan Duda.
Connection Strength

3.228
  1. Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges. Nat Rev Clin Oncol. 2018 05; 15(5):325-340.
    View in: PubMed
    Score: 0.188
  2. Anti-VEGF therapy induces ECM remodeling and mechanical barriers to therapy in colorectal cancer liver metastases. Sci Transl Med. 2016 10 12; 8(360):360ra135.
    View in: PubMed
    Score: 0.170
  3. PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity. Clin Cancer Res. 2016 06 15; 22(12):2993-3004.
    View in: PubMed
    Score: 0.163
  4. From the Guest Editors: Role of Tumor Microenvironment in Tumor Progression and Treatment Response: A 30 Years' Journey. Cancer J. 2015 Jul-Aug; 21(4):235-6.
    View in: PubMed
    Score: 0.156
  5. Lessons From 30 Years of Teaching About the Microenvironment of Tumors. Cancer J. 2015 May-Jun; 21(3):137.
    View in: PubMed
    Score: 0.154
  6. Quantum dot/antibody conjugates for in vivo cytometric imaging in mice. Proc Natl Acad Sci U S A. 2015 Feb 03; 112(5):1350-5.
    View in: PubMed
    Score: 0.151
  7. Studying primary tumor-associated fibroblast involvement in cancer metastasis in mice. Nat Protoc. 2012 Mar 22; 7(4):756-62.
    View in: PubMed
    Score: 0.124
  8. A transient parabiosis skin transplantation model in mice. Nat Protoc. 2012 Mar 22; 7(4):763-70.
    View in: PubMed
    Score: 0.124
  9. CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies? Clin Cancer Res. 2011 Apr 15; 17(8):2074-80.
    View in: PubMed
    Score: 0.115
  10. Malignant cells facilitate lung metastasis by bringing their own soil. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21677-82.
    View in: PubMed
    Score: 0.113
  11. Tumor microvasculature and microenvironment: novel insights through intravital imaging in pre-clinical models. Microcirculation. 2010 Apr; 17(3):206-25.
    View in: PubMed
    Score: 0.108
  12. Histopathologic findings and establishment of novel tumor lines from spontaneous tumors in FVB/N mice. Comp Med. 2008 Jun; 58(3):253-63.
    View in: PubMed
    Score: 0.095
  13. Evidence for incorporation of bone marrow-derived endothelial cells into perfused blood vessels in tumors. Blood. 2006 Apr 01; 107(7):2774-6.
    View in: PubMed
    Score: 0.080
  14. Engineering vascularized tissue. Nat Biotechnol. 2005 Jul; 23(7):821-3.
    View in: PubMed
    Score: 0.078
  15. Differential transplantability of tumor-associated stromal cells. Cancer Res. 2004 Sep 01; 64(17):5920-4.
    View in: PubMed
    Score: 0.074
  16. Role of eNOS in neovascularization: NO for endothelial progenitor cells. Trends Mol Med. 2004 Apr; 10(4):143-5.
    View in: PubMed
    Score: 0.071
  17. Paracrine regulation of angiogenesis and adipocyte differentiation during in vivo adipogenesis. Circ Res. 2003 Oct 31; 93(9):e88-97.
    View in: PubMed
    Score: 0.069
  18. Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy. Proc Natl Acad Sci U S A. 2021 11 09; 118(45).
    View in: PubMed
    Score: 0.061
  19. FATTY ACID SYNTHESIS IS REQUIRED FOR BREAST CANCER BRAIN METASTASIS. Nat Cancer. 2021 Apr; 2(4):414-428.
    View in: PubMed
    Score: 0.058
  20. Combining losartan with radiotherapy increases tumor control and inhibits lung metastases from a HER2/neu-positive orthotopic breast cancer model. Radiat Oncol. 2021 Mar 04; 16(1):48.
    View in: PubMed
    Score: 0.058
  21. Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy. Nat Biotechnol. 2020 04; 38(4):420-425.
    View in: PubMed
    Score: 0.054
  22. Dual endothelin receptor inhibition enhances T-DM1 efficacy in brain metastases from HER2-positive breast cancer. NPJ Breast Cancer. 2019; 5:4.
    View in: PubMed
    Score: 0.050
  23. Obesity promotes resistance to anti-VEGF therapy in breast cancer by up-regulating IL-6 and potentially FGF-2. Sci Transl Med. 2018 03 14; 10(432).
    View in: PubMed
    Score: 0.047
  24. A cerebellar window for intravital imaging of normal and disease states in mice. Nat Protoc. 2017 Nov; 12(11):2251-2262.
    View in: PubMed
    Score: 0.046
  25. The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation. Sci Transl Med. 2017 05 24; 9(391).
    View in: PubMed
    Score: 0.044
  26. Corrigendum: Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity. Cold Spring Harb Perspect Med. 2016 12 01; 6(12).
    View in: PubMed
    Score: 0.043
  27. Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity. Cold Spring Harb Perspect Med. 2016 Dec 01; 6(12).
    View in: PubMed
    Score: 0.043
  28. Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages. Proc Natl Acad Sci U S A. 2016 Apr 19; 113(16):4470-5.
    View in: PubMed
    Score: 0.041
  29. Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival. Proc Natl Acad Sci U S A. 2016 Apr 19; 113(16):4476-81.
    View in: PubMed
    Score: 0.041
  30. Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment. J Natl Cancer Inst. 2016 Feb; 108(2).
    View in: PubMed
    Score: 0.040
  31. Vascular diseases await translation of blood vessels engineered from stem cells. Sci Transl Med. 2015 Oct 14; 7(309):309rv6.
    View in: PubMed
    Score: 0.040
  32. Micelle-Encapsulated Quantum Dot-Porphyrin Assemblies as in Vivo Two-Photon Oxygen Sensors. J Am Chem Soc. 2015 Aug 12; 137(31):9832-42.
    View in: PubMed
    Score: 0.039
  33. Benefits of vascular normalization are dose and time dependent--letter. Cancer Res. 2013 Dec 01; 73(23):7144-6.
    View in: PubMed
    Score: 0.035
  34. Effects of vascular-endothelial protein tyrosine phosphatase inhibition on breast cancer vasculature and metastatic progression. J Natl Cancer Inst. 2013 Aug 21; 105(16):1188-201.
    View in: PubMed
    Score: 0.034
  35. Generation of functionally competent and durable engineered blood vessels from human induced pluripotent stem cells. Proc Natl Acad Sci U S A. 2013 Jul 30; 110(31):12774-9.
    View in: PubMed
    Score: 0.034
  36. Targeting placental growth factor/neuropilin 1 pathway inhibits growth and spread of medulloblastoma. Cell. 2013 Feb 28; 152(5):1065-76.
    View in: PubMed
    Score: 0.033
  37. Vascular normalization as an emerging strategy to enhance cancer immunotherapy. Cancer Res. 2013 May 15; 73(10):2943-8.
    View in: PubMed
    Score: 0.033
  38. Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17561-6.
    View in: PubMed
    Score: 0.032
  39. An isolated tumor perfusion model in mice. Nat Protoc. 2012 Mar 22; 7(4):749-55.
    View in: PubMed
    Score: 0.031
  40. Normalization of the vasculature for treatment of cancer and other diseases. Physiol Rev. 2011 Jul; 91(3):1071-121.
    View in: PubMed
    Score: 0.030
  41. Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation. Proc Natl Acad Sci U S A. 2011 Mar 01; 108(9):3725-30.
    View in: PubMed
    Score: 0.029
  42. C-X-C receptor type 4 promotes metastasis by activating p38 mitogen-activated protein kinase in myeloid differentiation antigen (Gr-1)-positive cells. Proc Natl Acad Sci U S A. 2011 Jan 04; 108(1):302-7.
    View in: PubMed
    Score: 0.028
  43. VEGFR1 activity modulates myeloid cell infiltration in growing lung metastases but is not required for spontaneous metastasis formation. PLoS One. 2009 Sep 18; 4(9):e6525.
    View in: PubMed
    Score: 0.026
  44. VEGFR1-activity-independent metastasis formation. Nature. 2009 Sep 17; 461(7262):E4; discussion E5.
    View in: PubMed
    Score: 0.026
  45. Paradoxical effects of PDGF-BB overexpression in endothelial cells on engineered blood vessels in vivo. Am J Pathol. 2009 Jul; 175(1):294-302.
    View in: PubMed
    Score: 0.026
  46. Blockade of VEGFR2 and not VEGFR1 can limit diet-induced fat tissue expansion: role of local versus bone marrow-derived endothelial cells. PLoS One. 2009; 4(3):e4974.
    View in: PubMed
    Score: 0.025
  47. Edema control by cediranib, a vascular endothelial growth factor receptor-targeted kinase inhibitor, prolongs survival despite persistent brain tumor growth in mice. J Clin Oncol. 2009 May 20; 27(15):2542-52.
    View in: PubMed
    Score: 0.025
  48. Differential in vivo potential of endothelial progenitor cells from human umbilical cord blood and adult peripheral blood to form functional long-lasting vessels. Blood. 2008 Feb 01; 111(3):1302-5.
    View in: PubMed
    Score: 0.023
  49. Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo. Nat Med. 2005 Jun; 11(6):678-82.
    View in: PubMed
    Score: 0.019
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.