Harvard Catalyst Profiles

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Francis X. McGowan Jr., M.D.

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Mentoring
LPS and Inflammation Response in the Heart
Full Time/Year Long, 07/31/00 - 07/31/01

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P50HL074734 (NEWBURGER, JANE W.) Feb 15, 2004 - Jan 31, 2010
    NIH
    SSCOR in Pediatric Heart Development and Disease
    Role: Co-Principal Investigator
  2. R01HL066186 (MCGOWAN, FRANCIS X) Jan 1, 2001 - Dec 31, 2006
    NIH
    CASPASE INHIBITION OF APOPTOSIS, INFANT CARDIAC SURGERY
    Role: Principal Investigator
  3. R01HL052589 (MCGOWAN, FRANCIS X) Mar 1, 1996 - Feb 29, 2000
    NIH
    Myocardial Endotoxin Signaling in Surgery
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Weiss SL, Bittinger K, Lee JJ, Friedman ES, Mattei LM, Graham K, Zhang D, Bush J, Balamuth F, McGowan FX, Bushman FD, Baldassano RN, Wu GD, Wallace DC, Collman RG. Decreased Intestinal Microbiome Diversity in Pediatric Sepsis: A Conceptual Framework for Intestinal Dysbiosis to Influence Immunometabolic Function. Crit Care Explor. 2021 Mar; 3(3):e0360. PMID: 33786436.
    Citations:    
  2. Garcia-Marcinkiewicz AG, Kovatsis PG, Hunyady AI, Olomu PN, Zhang B, Sathyamoorthy M, Gonzalez A, Kanmanthreddy S, Gálvez JA, Franz AM, Peyton J, Park R, Kiss EE, Sommerfield D, Griffis H, Nishisaki A, von Ungern-Sternberg BS, Nadkarni VM, McGowan FX, Fiadjoe JE. First-attempt success rate of video laryngoscopy in small infants (VISI): a multicentre, randomised controlled trial. Lancet. 2020 12 12; 396(10266):1905-1913. PMID: 33308472.
    Citations:    Fields:    Translation:Humans
  3. Himebauch AS, Wong W, Wang Y, McGowan FX, Berg RA, Mascio CE, Kilbaugh TJ, Lin KY, Goldfarb SB, Kawut SM, Mercer-Rosa L, Yehya N. Preoperative echocardiographic parameters predict primary graft dysfunction following pediatric lung transplantation. Pediatr Transplant. 2021 Mar; 25(2):e13858. PMID: 33073484.
    Citations:    Fields:    
  4. Weiss SL, Zhang D, Bush J, Graham K, Starr J, Murray J, Tuluc F, Henrickson S, Deutschman CS, Becker L, McGowan FX, Wallace DC. Mitochondrial Dysfunction is Associated With an Immune Paralysis Phenotype in Pediatric Sepsis. Shock. 2020 09; 54(3):285-293. PMID: 31764621.
    Citations: 4     Fields:    
  5. Morgan RW, Topjian AA, Wang Y, Atkin NJ, Kilbaugh TJ, McGowan FX, Berg RA, Mercer-Rosa L, Sutton RM, Himebauch AS. Prevalence and Outcomes of Pediatric In-Hospital Cardiac Arrest Associated With Pulmonary Hypertension. Pediatr Crit Care Med. 2020 04; 21(4):305-313. PMID: 31688674.
    Citations:    Fields:    Translation:Humans
  6. Himebauch AS, Yehya N, Wang Y, McGowan FX, Mercer-Rosa L. New or Persistent Right Ventricular Systolic Dysfunction Is Associated With Worse Outcomes in Pediatric Acute Respiratory Distress Syndrome. Pediatr Crit Care Med. 2020 02; 21(2):e121-e128. PMID: 31851127.
    Citations: 3     Fields:    Translation:Humans
  7. Weiss SL, Zhang D, Bush J, Graham K, Starr J, Tuluc F, Henrickson S, Kilbaugh T, Deutschman CS, Murdock D, McGowan FX, Becker L, Wallace DC. Persistent Mitochondrial Dysfunction Linked to Prolonged Organ Dysfunction in Pediatric Sepsis. Crit Care Med. 2019 10; 47(10):1433-1441. PMID: 31385882.
    Citations: 6     Fields:    Translation:HumansCells
  8. Jiang J, Hoagland D, Palatinus JA, He H, Iyyathurai J, Jourdan LJ, Bultynck G, Wang Z, Zhang Z, Schey K, Poelzing S, McGowan FX, Gourdie RG. Interaction of a Carboxyl Terminus 1 Peptide With the Connexin 43 Carboxyl Terminus Preserves Left Ventricular Function After Ischemia-Reperfusion Injury. J Am Heart Assoc. 2019 08 20; 8(16):e012385. PMID: 31422747.
    Citations: 5     Fields:    Translation:AnimalsCells
  9. Nguyen AV, Lasso A, Nam HH, Faerber J, Aly AH, Pouch AM, Scanlan AB, McGowan FX, Mercer-Rosa L, Cohen MS, Simpson J, Fichtinger G, Jolley MA. Dynamic Three-Dimensional Geometry of the Tricuspid Valve Annulus in Hypoplastic Left Heart Syndrome with a Fontan Circulation. J Am Soc Echocardiogr. 2019 05; 32(5):655-666.e13. PMID: 30826226.
    Citations: 2     Fields:    Translation:Humans
  10. Szmuk P, Andropoulos D, McGowan F, Brambrink A, Lee C, Lee KJ, McCann ME, Liu Y, Saynhalath R, Bong CL, Anderson BJ, Berde C, De Graaff JC, Disma N, Kurth D, Loepke A, Orser B, Sessler DI, Skowno JJ, von Ungern-Sternberg BS, Vutskits L, Davidson A. An open label pilot study of a dexmedetomidine-remifentanil-caudal anesthetic for infant lower abdominal/lower extremity surgery: The T REX pilot study. Paediatr Anaesth. 2019 01; 29(1):59-67. PMID: 30428151.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  11. Jolley MA, Lasso A, Nam HH, Dinh PV, Scanlan AB, Nguyen AV, Ilina A, Morray B, Glatz AC, McGowan FX, Whitehead K, Dori Y, Gorman JH, Gorman RC, Fichtinger G, Gillespie MJ. Toward predictive modeling of catheter-based pulmonary valve replacement into native right ventricular outflow tracts. Catheter Cardiovasc Interv. 2019 02 15; 93(3):E143-E152. PMID: 30444053.
    Citations: 5     Fields:    Translation:HumansAnimals
  12. Himebauch AS, Yehya N, Wang Y, Conlon T, Kilbaugh TJ, McGowan FX, Mercer-Rosa L. Early Right Ventricular Systolic Dysfunction and Pulmonary Hypertension Are Associated With Worse Outcomes in Pediatric Acute Respiratory Distress Syndrome. Crit Care Med. 2018 11; 46(11):e1055-e1062. PMID: 30095502.
    Citations: 7     Fields:    Translation:Humans
  13. Lasso A, Nam HH, Dinh PV, Pinter C, Fillion-Robin JC, Pieper S, Jhaveri S, Vimort JB, Martin K, Asselin M, McGowan FX, Kikinis R, Fichtinger G, Jolley MA. Interaction with Volume-Rendered Three-Dimensional Echocardiographic Images in Virtual Reality. J Am Soc Echocardiogr. 2018 10; 31(10):1158-1160. PMID: 30093145.
    Citations: 5     Fields:    Translation:Humans
  14. Olbrecht VA, Skowno J, Marchesini V, Ding L, Jiang Y, Ward CG, Yu G, Liu H, Schurink B, Vutskits L, de Graaff JC, McGowan FX, von Ungern-Sternberg BS, Kurth CD, Davidson A. An International, Multicenter, Observational Study of Cerebral Oxygenation during Infant and Neonatal Anesthesia. Anesthesiology. 2018 01; 128(1):85-96. PMID: 29019815.
    Citations: 6     Fields:    Translation:Humans
  15. Scanlan AB, Nguyen AV, Ilina A, Lasso A, Cripe L, Jegatheeswaran A, Silvestro E, McGowan FX, Mascio CE, Fuller S, Spray TL, Cohen MS, Fichtinger G, Jolley MA. Comparison of 3D Echocardiogram-Derived 3D Printed Valve Models to Molded Models for Simulated Repair of Pediatric Atrioventricular Valves. Pediatr Cardiol. 2018 Mar; 39(3):538-547. PMID: 29181795.
    Citations: 9     Fields:    Translation:Humans
  16. Perry DA, Salvin JW, Romfh P, Chen P, Krishnamurthy K, Thomson LM, Polizzotti BD, McGowan FX, Vakhshoori D, Kheir JN. Responsive monitoring of mitochondrial redox states in heart muscle predicts impending cardiac arrest. Sci Transl Med. 2017 Sep 20; 9(408). PMID: 28931652.
    Citations: 5     Fields:    Translation:AnimalsCells
  17. Kussman BD, Laussen PC, Benni PB, McGowan FX, McElhinney DB. Cerebral Oxygen Saturation in Children With Congenital Heart Disease and Chronic Hypoxemia. Anesth Analg. 2017 07; 125(1):234-240. PMID: 28514318.
    Citations: 7     Fields:    Translation:Humans
  18. Pouch AM, Aly AH, Lasso A, Nguyen AV, Scanlan AB, McGowan FX, Fichtinger G, Gorman RC, Gorman JH, Yushkevich PA, Jolley MA. Image Segmentation and Modeling of the Pediatric Tricuspid Valve in Hypoplastic Left Heart Syndrome. Funct Imaging Model Heart. 2017; 10263:95-105. PMID: 29756127.
    Citations: 4     
  19. Levy RJ, Herbstman JB, Bosnjak ZJ, Loepke AW, McGowan FX. Biomarkers, Genetics, and Epigenetic Studies to Explore the Neurocognitive Effects of Anesthesia in Children. J Neurosurg Anesthesiol. 2016 Oct; 28(4):384-388. PMID: 27564554.
    Citations: 1     Fields:    
  20. Sun LS, Li G, Miller TL, Salorio C, Byrne MW, Bellinger DC, Ing C, Park R, Radcliffe J, Hays SR, DiMaggio CJ, Cooper TJ, Rauh V, Maxwell LG, Youn A, McGowan FX. Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood. JAMA. 2016 Jun 07; 315(21):2312-20. PMID: 27272582.
    Citations: 123     Fields:    Translation:Humans
  21. DeWitt ES, Black KJ, Thiagarajan RR, DiNardo JA, Colan SD, McGowan FX, Kheir JN. Effects of commonly used inotropes on myocardial function and oxygen consumption under constant ventricular loading conditions. J Appl Physiol (1985). 2016 07 01; 121(1):7-14. PMID: 27150829.
    Citations: 4     Fields:    Translation:Animals
  22. Philip Saul J, Kanter RJ, Abrams D, Asirvatham S, Bar-Cohen Y, Blaufox AD, Cannon B, Clark J, Dick M, Freter A, Kertesz NJ, Kirsh JA, Kugler J, LaPage M, McGowan FX, Miyake CY, Nathan A, Papagiannis J, Paul T, Pflaumer A, Skanes AC, Stevenson WG, Von Bergen N, Zimmerman F. PACES/HRS expert consensus statement on the use of catheter ablation in children and patients with congenital heart disease: Developed in partnership with the Pediatric and Congenital Electrophysiology Society (PACES) and the Heart Rhythm Society (HRS). Endorsed by the governing bodies of PACES, HRS, the American Academy of Pediatrics (AAP), the American Heart Association (AHA), and the Association for European Pediatric and Congenital Cardiology (AEPC). Heart Rhythm. 2016 06; 13(6):e251-89. PMID: 26899545.
    Citations: 25     Fields:    Translation:Humans
  23. Fiadjoe JE, Nishisaki A, Jagannathan N, Hunyady AI, Greenberg RS, Reynolds PI, Matuszczak ME, Rehman MA, Polaner DM, Szmuk P, Nadkarni VM, McGowan FX, Litman RS, Kovatsis PG. Airway management complications in children with difficult tracheal intubation from the Pediatric Difficult Intubation (PeDI) registry: a prospective cohort analysis. Lancet Respir Med. 2016 Jan; 4(1):37-48. PMID: 26705976.
    Citations: 20     Fields:    Translation:Humans
  24. Ward CG, Hines SJ, Maxwell LG, McGowan FX, Sun LS. Neurotoxicity, general anesthesia in young children, and a survey of current pediatric anesthesia practice at US teaching institutions. Paediatr Anaesth. 2016 Jan; 26(1):60-5. PMID: 26559907.
    Citations: 5     Fields:    Translation:Humans
  25. Wesley MC, Pereira LM, Scharp LA, Emani SM, McGowan FX, DiNardo JA. Pharmacokinetics of tranexamic acid in neonates, infants, and children undergoing cardiac surgery with cardiopulmonary bypass. Anesthesiology. 2015 Apr; 122(4):746-58. PMID: 25585004.
    Citations: 9     Fields:    Translation:Humans
  26. Nathan AT, Nicolson SC, McGowan FX. A word of caution: dexmedetomidine and pulmonary hypertension. Anesth Analg. 2014 Jul; 119(1):216-7. PMID: 24945133.
    Citations: 1     Fields:    Translation:Humans
  27. Costello JM, Dunbar-Masterson C, Allan CK, Gauvreau K, Newburger JW, McGowan FX, Wessel DL, Mayer JE, Salvin JW, Dionne RE, Laussen PC. Impact of empiric nesiritide or milrinone infusion on early postoperative recovery after Fontan surgery: a randomized, double-blind, placebo-controlled trial. Circ Heart Fail. 2014 Jul; 7(4):596-604. PMID: 24906491.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  28. McGowan FX, Davis PJ. The advanced pediatric anesthesiology fellowship: moving beyond a clinical apprenticeship. Anesth Analg. 2014 Apr; 118(4):701-3. PMID: 24651221.
    Citations:    Fields:    Translation:Humans
  29. He H, Tao H, Xiong H, Duan SZ, McGowan FX, Mortensen RM, Balschi JA. Rosiglitazone causes cardiotoxicity via peroxisome proliferator-activated receptor ?-independent mitochondrial oxidative stress in mouse hearts. Toxicol Sci. 2014 Apr; 138(2):468-81. PMID: 24449420.
    Citations: 19     Fields:    Translation:AnimalsCells
  30. Polizzotti BD, Thomson LM, O'Connell DW, McGowan FX, Kheir JN. Optimization and characterization of stable lipid-based, oxygen-filled microbubbles by mixture design. . 2014 Aug; 102(6):1148-56. PMID: 24425069.
    Citations: 6     
  31. Xiong D, He H, James J, Tokunaga C, Powers C, Huang Y, Osinska H, Towbin JA, Purevjav E, Balschi JA, Javadov S, McGowan FX, Strauss AW, Khuchua Z. Cardiac-specific VLCAD deficiency induces dilated cardiomyopathy and cold intolerance. . 2014 Feb; 306(3):H326-38. PMID: 24285112.
    Citations: 17     Translation:AnimalsCells
  32. Bartholomä MD, He H, Pacak CA, Dunning P, Fahey FH, McGowan FX, Cowan DB, Treves ST, Packard AB. Biological characterization of F-18-labeled rhodamine B, a potential positron emission tomography perfusion tracer. Nucl Med Biol. 2013 Nov; 40(8):1043-8. PMID: 24011396.
    Citations: 3     Fields:    Translation:AnimalsCells
  33. Graham EM, Atz AM, McHugh KE, Butts RJ, Baker NL, Stroud RE, Reeves ST, Bradley SM, McGowan FX, Spinale FG. Preoperative steroid treatment does not improve markers of inflammation after cardiac surgery in neonates: results from a randomized trial. J Thorac Cardiovasc Surg. 2014 Mar; 147(3):902-8. PMID: 23870160.
    Citations: 19     Fields:    Translation:Humans
  34. Kheir JN, Polizzotti BD, Thomson LM, O'Connell DW, Black KJ, Lee RW, Wilking JN, Graham AC, Bell DC, McGowan FX. Bulk manufacture of concentrated oxygen gas-filled microparticles for intravenous oxygen delivery. Adv Healthc Mater. 2013 Aug; 2(8):1131-41. PMID: 23471884.
    Citations: 11     Fields:    Translation:AnimalsCells
  35. Friehs I, Cowan DB, Choi YH, Black KM, Barnett R, Bhasin MK, Daly C, Dillon SJ, Libermann TA, McGowan FX, del Nido PJ, Levitsky S, McCully JD. Pressure-overload hypertrophy of the developing heart reveals activation of divergent gene and protein pathways in the left and right ventricular myocardium. . 2013 Mar 01; 304(5):H697-708. PMID: 23262132.
    Citations: 8     Translation:AnimalsCells
  36. Graham EM, Taylor SN, Zyblewski SC, Wolf B, Bradley SM, Hollis BW, McGowan FX, Atz AM. Vitamin D status in neonates undergoing cardiac operations: relationship to cardiopulmonary bypass and association with outcomes. J Pediatr. 2013 Apr; 162(4):823-6. PMID: 23149171.
    Citations: 8     Fields:    Translation:Humans
  37. Sun LS, Li G, DiMaggio CJ, Byrne MW, Ing C, Miller TL, Bellinger DC, Han S, McGowan FX. Feasibility and pilot study of the Pediatric Anesthesia NeuroDevelopment Assessment (PANDA) project. J Neurosurg Anesthesiol. 2012 Oct; 24(4):382-8. PMID: 23076226.
    Citations: 19     Fields:    Translation:HumansAnimals
  38. Nikolova A, Ablasser K, Wyler von Ballmoos MC, Poutias D, Kaza E, McGowan FX, Moses MA, Del Nido PJ, Friehs I. Endogenous angiogenesis inhibitors prevent adaptive capillary growth in left ventricular pressure overload hypertrophy. Ann Thorac Surg. 2012 Nov; 94(5):1509-17. PMID: 22795062.
    Citations: 8     Fields:    Translation:Animals
  39. Kheir JN, Scharp LA, Borden MA, Swanson EJ, Loxley A, Reese JH, Black KJ, Velazquez LA, Thomson LM, Walsh BK, Mullen KE, Graham DA, Lawlor MW, Brugnara C, Bell DC, McGowan FX. Oxygen gas-filled microparticles provide intravenous oxygen delivery. Sci Transl Med. 2012 Jun 27; 4(140):140ra88. PMID: 22745438.
    Citations: 21     Fields:    Translation:Animals
  40. Mehta NM, Costello JM, Bechard LJ, Johnson VM, Zurakowski D, McGowan FX, Laussen PC, Duggan CP. Resting energy expenditure after Fontan surgery in children with single-ventricle heart defects. JPEN J Parenter Enteral Nutr. 2012 Nov; 36(6):685-92. PMID: 22539159.
    Citations: 3     Fields:    Translation:Humans
  41. Graham EM, Atz AM, Gillis J, Desantis SM, Haney AL, Deardorff RL, Uber WE, Reeves ST, McGowan FX, Bradley SM, Spinale FG. Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery. J Thorac Cardiovasc Surg. 2012 May; 143(5):1069-76. PMID: 22075061.
    Citations: 5     Fields:    Translation:Humans
  42. Chow MJ, Zou Y, He H, McGowan FX, Zurakowski D, Zhang Y. Obstruction-induced pulmonary vascular remodeling. J Biomech Eng. 2011 Nov; 133(11):111009. PMID: 22168741.
    Citations: 3     Fields:    Translation:Animals
  43. Zhou B, Honor LB, He H, Ma Q, Oh JH, Butterfield C, Lin RZ, Melero-Martin JM, Dolmatova E, Duffy HS, Gise Av, Zhou P, Hu YW, Wang G, Zhang B, Wang L, Hall JL, Moses MA, McGowan FX, Pu WT. Adult mouse epicardium modulates myocardial injury by secreting paracrine factors. J Clin Invest. 2011 May; 121(5):1894-904. PMID: 21505261.
    Citations: 220     Fields:    Translation:AnimalsCells
  44. Goobie SM, Meier PM, Pereira LM, McGowan FX, Prescilla RP, Scharp LA, Rogers GF, Proctor MR, Meara JG, Soriano SG, Zurakowski D, Sethna NF. Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial. Anesthesiology. 2011 Apr; 114(4):862-71. PMID: 21364458.
    Citations: 29     Fields:    Translation:Humans
  45. Salvin JW, Scheurer MA, Laussen PC, Wypij D, Polito A, Bacha EA, Pigula FA, McGowan FX, Costello JM, Thiagarajan RR. Blood transfusion after pediatric cardiac surgery is associated with prolonged hospital stay. Ann Thorac Surg. 2011 Jan; 91(1):204-10. PMID: 21172513.
    Citations: 22     Fields:    Translation:Humans
  46. Allan CK, Newburger JW, McGrath E, Elder J, Psoinos C, Laussen PC, del Nido PJ, Wypij D, McGowan FX. The relationship between inflammatory activation and clinical outcome after infant cardiopulmonary bypass. Anesth Analg. 2010 Nov; 111(5):1244-51. PMID: 20829561.
    Citations: 35     Fields:    Translation:Humans
  47. Levy RJ, Nasr VG, Rivera O, Roberts R, Slack M, Kanter JP, Ratnayaka K, Kaplan RF, McGowan FX. Detection of carbon monoxide during routine anesthetics in infants and children. Anesth Analg. 2010 Mar 01; 110(3):747-53. PMID: 20185653.
    Citations: 7     Fields:    Translation:HumansCells
  48. Griffiths ER, Friehs I, Scherr E, Poutias D, McGowan FX, Del Nido PJ. Electron transport chain dysfunction in neonatal pressure-overload hypertrophy precedes cardiomyocyte apoptosis independent of oxidative stress. J Thorac Cardiovasc Surg. 2010 Jun; 139(6):1609-17. PMID: 20038480.
    Citations: 15     Fields:    Translation:Animals
  49. Wolf CM, Seslar SP, den Boer K, Juraszek AL, McGowan FX, Cowan DB, Del Nido P, Triedman JK, Berul CI, Walsh EP. Atrial remodeling after the Fontan operation. Am J Cardiol. 2009 Dec 15; 104(12):1737-42. PMID: 19962486.
    Citations: 8     Fields:    Translation:Humans
  50. Perez AL, Bachrach E, Illigens BM, Jun SJ, Bagden E, Steffen L, Flint A, McGowan FX, Del Nido P, Montecino-Rodriguez E, Tidball JG, Kunkel LM. CXCR4 enhances engraftment of muscle progenitor cells. Muscle Nerve. 2009 Oct; 40(4):562-72. PMID: 19760789.
    Citations: 15     Fields:    Translation:AnimalsCells
  51. Kitahori K, He H, Kawata M, Cowan DB, Friehs I, Del Nido PJ, McGowan FX. Development of left ventricular diastolic dysfunction with preservation of ejection fraction during progression of infant right ventricular hypertrophy. Circ Heart Fail. 2009 Nov; 2(6):599-607. PMID: 19919985.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  52. Vitali SH, Mitsialis SA, Liang OD, Liu X, Fernandez-Gonzalez A, Christou H, Wu X, McGowan FX, Kourembanas S. Divergent cardiopulmonary actions of heme oxygenase enzymatic products in chronic hypoxia. PLoS One. 2009 Jun 19; 4(6):e5978. PMID: 19543386.
    Citations: 14     Fields:    Translation:AnimalsCells
  53. Zhou B, Ma Q, Kong SW, Hu Y, Campbell PH, McGowan FX, Ackerman KG, Wu B, Zhou B, Tevosian SG, Pu WT. Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart. J Clin Invest. 2009 Jun; 119(6):1462-76. PMID: 19411759.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  54. McCully JD, Bhasin MK, Daly C, Guerrero MC, Dillon S, Liberman TA, Cowan DB, Mably JD, McGowan FX, Levitsky S. Transcriptomic and proteomic analysis of global ischemia and cardioprotection in the rabbit heart. Physiol Genomics. 2009 Jul 09; 38(2):125-37. PMID: 19454556.
    Citations: 11     Fields:    Translation:AnimalsCells
  55. Wesley MC, McGowan FX, Castro RA, Dissanayake S, Zurakowski D, Dinardo JA. The effect of milrinone on platelet activation as determined by TEG platelet mapping. Anesth Analg. 2009 May; 108(5):1425-9. PMID: 19372315.
    Citations: 7     Fields:    Translation:HumansCells
  56. Gonnella PA, Del Nido PJ, McGowan FX. Oral tolerization with cardiac myosin peptide (614-629) ameliorates experimental autoimmune myocarditis: role of STAT 6 genes in BALB/CJ mice. J Clin Immunol. 2009 Jul; 29(4):434-43. PMID: 19353248.
    Citations: 7     Fields:    Translation:Animals
  57. Choi YH, Cowan DB, Moran AM, Colan SD, Stamm C, Takeuchi K, Friehs I, del Nido PJ, McGowan FX. Myocyte apoptosis occurs early during the development of pressure-overload hypertrophy in infant myocardium. J Thorac Cardiovasc Surg. 2009 Jun; 137(6):1356-62, 1362.e1-3. PMID: 19464448.
    Citations: 8     Fields:    Translation:AnimalsCells
  58. Odegard KC, Zurakowski D, DiNardo JA, Castro RA, McGowan FX, Neufeld EJ, Laussen PC. Prospective longitudinal study of coagulation profiles in children with hypoplastic left heart syndrome from stage I through Fontan completion. J Thorac Cardiovasc Surg. 2009 Apr; 137(4):934-41. PMID: 19327521.
    Citations: 13     Fields:    Translation:Humans
  59. Choi YH, Cowan DB, Nathan M, Poutias D, Stamm C, del Nido PJ, McGowan FX. Myocardial hypertrophy overrides the angiogenic response to hypoxia. PLoS One. 2008; 3(12):e4042. PMID: 19112498.
    Citations: 8     Fields:    Translation:Animals
  60. Burch TM, McGowan FX, Kussman BD, Powell AJ, DiNardo JA. Congenital supravalvular aortic stenosis and sudden death associated with anesthesia: what's the mystery? Anesth Analg. 2008 Dec; 107(6):1848-54. PMID: 19020129.
    Citations: 8     Fields:    Translation:Humans
  61. Gonnella PA, Waldner H, Del Nido PJ, McGowan FX. Inhibition of experimental autoimmune myocarditis: peripheral deletion of TcR Vbeta 8.1, 8.2+ CD4+ T cells in TLR-4 deficient mice. J Autoimmun. 2008 Sep; 31(2):180-7. PMID: 18715752.
    Citations: 5     Fields:    Translation:AnimalsCells
  62. Mullen MP, Wessel DL, Thomas KC, Gauvreau K, Neufeld EJ, McGowan FX, Dinardo JA. The incidence and implications of anti-heparin-platelet factor 4 antibody formation in a pediatric cardiac surgical population. Anesth Analg. 2008 Aug; 107(2):371-8. PMID: 18633010.
    Citations: 6     Fields:    Translation:Humans
  63. Tabbutt S, Nicolson SC, Adamson PC, Zhang X, Hoffman ML, Wells W, Backer CL, McGowan FX, Tweddell JS, Bokesch P, Schreiner M. The safety, efficacy, and pharmacokinetics of esmolol for blood pressure control immediately after repair of coarctation of the aorta in infants and children: a multicenter, double-blind, randomized trial. J Thorac Cardiovasc Surg. 2008 Aug; 136(2):321-8. PMID: 18692637.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  64. Loepke AW, McGowan FX, Soriano SG. CON: The toxic effects of anesthetics in the developing brain: the clinical perspective. Anesth Analg. 2008 Jun; 106(6):1664-9. PMID: 18499595.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  65. McGowan FX, Davis PJ. Anesthetic-related neurotoxicity in the developing infant: of mice, rats, monkeys and, possibly, humans. Anesth Analg. 2008 Jun; 106(6):1599-602. PMID: 18499584.
    Citations: 16     Fields:    Translation:HumansAnimals
  66. Sawasdiwipachai P, Laussen PC, McGowan FX, Smoot L, Casta A. Cardiac arrest after neuromuscular blockade reversal in a heart transplant infant. Anesthesiology. 2007 Oct; 107(4):663-5. PMID: 17893464.
    Citations: 8     Fields:    Translation:Humans
  67. Odegard KC, DiNardo JA, Kussman BD, Shukla A, Harrington J, Casta A, McGowan FX, Hickey PR, Bacha EA, Thiagarajan RR, Laussen PC. The frequency of anesthesia-related cardiac arrests in patients with congenital heart disease undergoing cardiac surgery. Anesth Analg. 2007 Aug; 105(2):335-43. PMID: 17646487.
    Citations: 6     Fields:    Translation:Humans
  68. Yuki K, Shamberger RC, McGowan FX, Seefelder C. The perioperative management of a patient with Fontan physiology for pheochromocytoma resection. J Cardiothorac Vasc Anesth. 2008 Oct; 22(5):748-50. PMID: 18922437.
    Citations: 4     Fields:    Translation:Humans
  69. Roy N, Friehs I, Cowan DB, Zurakowski D, McGowan FX, del Nido PJ. Dopamine induces postischemic cardiomyocyte apoptosis in vivo: an effect ameliorated by propofol. Ann Thorac Surg. 2006 Dec; 82(6):2192-9. PMID: 17126134.
    Citations: 6     Fields:    Translation:AnimalsCells
  70. Almond CS, Harrington J, Thiagarajan R, Duncan CN, LaPierre R, Halwick D, Blume ED, Del Nido PJ, Neufeld EJ, McGowan FX. Successful use of bivalirudin for cardiac transplantation in a child with heparin-induced thrombocytopenia. J Heart Lung Transplant. 2006 Nov; 25(11):1376-9. PMID: 17097505.
    Citations: 11     Fields:    Translation:Humans
  71. McClain CD, McGowan FX, Kovatsis PG. Laparoscopic surgery in a patient with Fontan physiology. Anesth Analg. 2006 Oct; 103(4):856-8. PMID: 17000793.
    Citations: 14     Fields:    Translation:Humans
  72. Cowan DB, McGowan FX. A paradigm shift in cardiac pacing therapy? Circulation. 2006 Sep 05; 114(10):986-8. PMID: 16952993.
    Citations: 1     Fields:    Translation:HumansAnimals
  73. Friehs I, Barillas R, Vasilyev NV, Roy N, McGowan FX, del Nido PJ. Vascular endothelial growth factor prevents apoptosis and preserves contractile function in hypertrophied infant heart. Circulation. 2006 Jul 04; 114(1 Suppl):I290-5. PMID: 16820588.
    Citations: 32     Fields:    Translation:AnimalsCells
  74. Takeuchi K, McGowan FX, Bacha EA, Mayer JE, Zurakowski D, Otaki M, del Nido PJ. Analysis of surgical outcome in complex double-outlet right ventricle with heterotaxy syndrome or complete atrioventricular canal defect. Ann Thorac Surg. 2006 Jul; 82(1):146-52. PMID: 16798205.
    Citations: 9     Fields:    Translation:Humans
  75. Choi YH, Stamm C, Hammer PE, Kwaku KF, Marler JJ, Friehs I, Jones M, Rader CM, Roy N, Eddy MT, Triedman JK, Walsh EP, McGowan FX, del Nido PJ, Cowan DB. Cardiac conduction through engineered tissue. Am J Pathol. 2006 Jul; 169(1):72-85. PMID: 16816362.
    Citations: 24     Fields:    Translation:AnimalsCells
  76. Bachrach E, Perez AL, Choi YH, Illigens BM, Jun SJ, del Nido P, McGowan FX, Li S, Flint A, Chamberlain J, Kunkel LM. Muscle engraftment of myogenic progenitor cells following intraarterial transplantation. Muscle Nerve. 2006 Jul; 34(1):44-52. PMID: 16634061.
    Citations: 29     Fields:    Translation:AnimalsCells
  77. Sethna NF, McGowan FX. Do results from studies of a simulated epidural test dose improve our ability to detect unintentional epidural vascular puncture in children? Paediatr Anaesth. 2005 Sep; 15(9):711-5. PMID: 16101700.
    Citations:    Fields:    Translation:Humans
  78. Kussman BD, Zurakowski D, Sullivan L, McGowan FX, Davis PJ, Laussen PC. Evaluation of plasma fentanyl concentrations in infants during cardiopulmonary bypass with low-volume circuits. J Cardiothorac Vasc Anesth. 2005 Jun; 19(3):316-21. PMID: 16130057.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  79. Friehs I, Cao-Danh H, Nathan M, McGowan FX, del Nido PJ. Impaired insulin-signaling in hypertrophied hearts contributes to ischemic injury. Biochem Biophys Res Commun. 2005 May 27; 331(1):15-22. PMID: 15845351.
    Citations: 7     Fields:    Translation:AnimalsCells
  80. Nathan M, Friehs I, Choi YH, Cowan DB, Cao-Danh H, McGowan FX, del Nido PJ. Cyclosporin A but not FK-506 protects against dopamine-induced apoptosis in the stunned heart. Ann Thorac Surg. 2005 May; 79(5):1620-6. PMID: 15854943.
    Citations: 5     Fields:    Translation:Animals
  81. Sparks JW, Seefelder C, Shamberger RC, McGowan FX. The perioperative management of a patient with complex single ventricle physiology and pheochromocytoma. Anesth Analg. 2005 Apr; 100(4):972-5. PMID: 15781508.
    Citations: 7     Fields:    Translation:Humans
  82. Friehs I, Moran AM, Stamm C, Choi YH, Cowan DB, McGowan FX, del Nido PJ. Promoting angiogenesis protects severely hypertrophied hearts from ischemic injury. Ann Thorac Surg. 2004 Jun; 77(6):2004-10; discussion 2011. PMID: 15172254.
    Citations: 23     Fields:    Translation:Animals
  83. Kussman BD, Geva T, McGowan FX. Cardiovascular causes of airway compression. Paediatr Anaesth. 2004 Jan; 14(1):60-74. PMID: 14717876.
    Citations: 30     Fields:    Translation:Humans
  84. Blum RH, McGowan FX. Chronic upper airway obstruction and cardiac dysfunction: anatomy, pathophysiology and anesthetic implications. Paediatr Anaesth. 2004 Jan; 14(1):75-83. PMID: 14717877.
    Citations: 9     Fields:    Translation:Humans
  85. Cowan DB, Jones M, Garcia LM, Noria S, del Nido PJ, McGowan FX. Hypoxia and stretch regulate intercellular communication in vascular smooth muscle cells through reactive oxygen species formation. Arterioscler Thromb Vasc Biol. 2003 Oct 01; 23(10):1754-60. PMID: 12958040.
    Citations: 11     Fields:    Translation:AnimalsCells
  86. Stamm C, Friehs I, Choi YH, Zurakowski D, McGowan FX, del Nido PJ. Cytosolic calcium in the ischemic rabbit heart: assessment by pH- and temperature-adjusted rhod-2 spectrofluorometry. Cardiovasc Res. 2003 Sep 01; 59(3):695-704. PMID: 14499871.
    Citations: 12     Fields:    Translation:AnimalsCells
  87. Friehs I, Cao-Danh H, Stamm C, Cowan DB, McGowan FX, del Nido PJ. Postnatal increase in insulin-sensitive glucose transporter expression is associated with improved recovery of postischemic myocardial function. J Thorac Cardiovasc Surg. 2003 Jul; 126(1):263-71. PMID: 12878964.
    Citations: 4     Fields:    Translation:Animals
  88. Odegard KC, McGowan FX, Zurakowski D, Dinardo JA, Castro RA, del Nido PJ, Laussen PC. Procoagulant and anticoagulant factor abnormalities following the Fontan procedure: increased factor VIII may predispose to thrombosis. J Thorac Cardiovasc Surg. 2003 Jun; 125(6):1260-7. PMID: 12830042.
    Citations: 19     Fields:    Translation:Humans
  89. Moran AM, Friehs I, Takeuchi K, Stamm C, Hammer PE, McGowan FX, del Nido PJ, Colan SD. Noninvasive serial evaluation of myocardial mechanics in pressure overload hypertrophy of rabbit myocardium. Herz. 2003 Feb; 28(1):52-62. PMID: 12616321.
    Citations: 10     Fields:    Translation:Animals
  90. Davis PJ, Stiller RL, Wilson AS, McGowan FX, Egan TD, Muir KT. In vitro remifentanil metabolism: the effects of whole blood constituents and plasma butyrylcholinesterase. Anesth Analg. 2002 Nov; 95(5):1305-7, table of contents. PMID: 12401616.
    Citations: 11     Fields:    Translation:HumansCellsCTClinical Trials
  91. Kussman BD, Devavaram P, Hansen DD, Dinardo JA, Forbess JM, Mehrota R, McGowan FX. Anesthetic implications of primary cardiac tumors in infants and children. J Cardiothorac Vasc Anesth. 2002 Oct; 16(5):582-6. PMID: 12407610.
    Citations:    Fields:    Translation:Humans
  92. Chanani NK, Cowan DB, Takeuchi K, Poutias DN, Garcia LM, del Nido PJ, McGowan FX. Differential effects of amrinone and milrinone upon myocardial inflammatory signaling. Circulation. 2002 Sep 24; 106(12 Suppl 1):I284-9. PMID: 12354747.
    Citations: 19     Fields:    Translation:AnimalsCells
  93. Stamm C, Friehs I, Cowan DB, Cao-Danh H, Choi YH, Duebener LF, McGowan FX, del Nido PJ. Dopamine treatment of postischemic contractile dysfunction rapidly induces calcium-dependent pro-apoptotic signaling. Circulation. 2002 Sep 24; 106(12 Suppl 1):I290-8. PMID: 12354748.
    Citations: 12     Fields:    Translation:AnimalsCells
  94. Odegard KC, McGowan FX, Zurakowski D, DiNardo JA, Castro RA, del Nido PJ, Laussen PC. Coagulation factor abnormalities in patients with single-ventricle physiology immediately prior to the Fontan procedure. Ann Thorac Surg. 2002 Jun; 73(6):1770-7. PMID: 12078768.
    Citations: 9     Fields:    Translation:Humans
  95. Takeuchi K, Simplaceanu E, McGowan FX, Tsushima T, del Nido PJ. L-arginine potentiates negative inotropic and metabolic effects to myocardium partly through the amiloride sensitive mechanism. Jpn J Physiol. 2002 Apr; 52(2):207-15. PMID: 12139779.
    Citations:    Fields:    Translation:AnimalsCells
  96. Munakata M, Stamm C, Friehs I, Zurakowski D, Cowan DB, Cao-Danh H, McGowan FX, del Nido PJ. Protective effects of protein kinase C during myocardial ischemia require activation of phosphatidyl-inositol specific phospholipase C. Ann Thorac Surg. 2002 Apr; 73(4):1236-45. PMID: 11998814.
    Citations: 3     Fields:    Translation:AnimalsCells
  97. Odegard KC, McGowan FX, DiNardo JA, Castro RA, Zurakowski D, Connor CM, Hansen DD, Neufeld EJ, del Nido PJ, Laussen PC. Coagulation abnormalities in patients with single-ventricle physiology precede the Fontan procedure. J Thorac Cardiovasc Surg. 2002 Mar; 123(3):459-65. PMID: 11882816.
    Citations: 12     Fields:    Translation:Humans
  98. Galinkin JL, Davis PJ, McGowan FX, Lynn AM, Rabb MF, Yaster M, Henson LG, Blum R, Hechtman D, Maxwell L, Szmuk P, Orr R, Krane EJ, Edwards S, Kurth CD. A randomized multicenter study of remifentanil compared with halothane in neonates and infants undergoing pyloromyotomy. II. Perioperative breathing patterns in neonates and infants with pyloric stenosis. Anesth Analg. 2001 Dec; 93(6):1387-92, table of contents. PMID: 11726412.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  99. Davis PJ, Galinkin J, McGowan FX, Lynn AM, Yaster M, Rabb MF, Krane EJ, Kurth CD, Blum RH, Maxwell L, Orr R, Szmuk P, Hechtman D, Edwards S, Henson LG. A randomized multicenter study of remifentanil compared with halothane in neonates and infants undergoing pyloromyotomy. I. Emergence and recovery profiles. Anesth Analg. 2001 Dec; 93(6):1380-6, table of contents. PMID: 11726411.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  100. Takeuchi K, Nagashima M, Itoh K, Minagawa M, Munakata M, Ichinoseki I, Fukui K, McGowan FX, del Nido PJ. Improving glucose metabolism and/or sarcoplasmic reticulum Ca2+-ATPase function is warranted for immature pressure overload hypertrophied myocardium. Jpn Circ J. 2001 Dec; 65(12):1064-70. PMID: 11767999.
    Citations:    Fields:    Translation:Animals
  101. Stamm C, Cowan DB, Friehs I, Noria S, del Nido PJ, McGowan FX. Rapid endotoxin-induced alterations in myocardial calcium handling: obligatory role of cardiac TNF-alpha. Anesthesiology. 2001 Dec; 95(6):1396-405. PMID: 11748398.
    Citations: 12     Fields:    Translation:AnimalsCells
  102. Ross AK, Davis PJ, Dear Gd GL, Ginsberg B, McGowan FX, Stiller RD, Henson LG, Huffman C, Muir KT. Pharmacokinetics of remifentanil in anesthetized pediatric patients undergoing elective surgery or diagnostic procedures. Anesth Analg. 2001 Dec; 93(6):1393-401, table of contents. PMID: 11726413.
    Citations: 43     Fields:    Translation:Humans
  103. Friehs I, Stamm C, Cao-Danh H, McGowan FX, del Nido PJ. Insulin-like growth factor-1 improves postischemic recovery in hypertrophied hearts. Ann Thorac Surg. 2001 Nov; 72(5):1650-6. PMID: 11722060.
    Citations: 6     Fields:    Translation:Animals
  104. Goobie SM, Soriano SG, Zurakowski D, McGowan FX, Rockoff MA. Hemostatic changes in pediatric neurosurgical patients as evaluated by thrombelastograph. Anesth Analg. 2001 Oct; 93(4):887-92. PMID: 11574351.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  105. Stamm C, Friehs I, Cowan DB, Moran AM, Cao-Danh H, Duebener LF, del Nido PJ, McGowan FX. Inhibition of tumor necrosis factor-alpha improves postischemic recovery of hypertrophied hearts. Circulation. 2001 Sep 18; 104(12 Suppl 1):I350-5. PMID: 11568081.
    Citations: 20     Fields:    Translation:AnimalsCells
  106. Stamm C, Friehs I, Cowan DB, Cao-Danh H, Noria S, Munakata M, McGowan FX, del Nido PJ. Post-ischemic PKC inhibition impairs myocardial calcium handling and increases contractile protein calcium sensitivity. Cardiovasc Res. 2001 Jul; 51(1):108-21. PMID: 11399253.
    Citations: 6     Fields:    Translation:Animals
  107. Gruber EM, Laussen PC, Casta A, Zimmerman AA, Zurakowski D, Reid R, Odegard KC, Chakravorti S, Davis PJ, McGowan FX, Hickey PR, Hansen DD. Stress response in infants undergoing cardiac surgery: a randomized study of fentanyl bolus, fentanyl infusion, and fentanyl-midazolam infusion. Anesth Analg. 2001 Apr; 92(4):882-90. PMID: 11273919.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  108. Cowan DB, Noria S, Stamm C, Garcia LM, Poutias DN, del Nido PJ, McGowan FX. Lipopolysaccharide internalization activates endotoxin-dependent signal transduction in cardiomyocytes. Circ Res. 2001 Mar 16; 88(5):491-8. PMID: 11249872.
    Citations: 15     Fields:    Translation:AnimalsCells
  109. MacGowan GA, Du C, Cowan DB, Stamm C, McGowan FX, Solaro RJ, Koretsky AP, Del Nido PJ. Ischemic dysfunction in transgenic mice expressing troponin I lacking protein kinase C phosphorylation sites. . 2001 Feb; 280(2):H835-43. PMID: 11158984.
    Citations: 17     Translation:AnimalsCells
  110. Luppi P, Licata A, Haluszczak C, Rudert WA, Trucco G, McGowan FX, Finegold D, Boyle GJ, Trucco M. Analysis of TCR Vbeta repertoire and cytokine gene expression in patients with idiopathic dilated cardiomyopathy. J Autoimmun. 2001 Feb; 16(1):3-13. PMID: 11221991.
    Citations: 3     Fields:    Translation:HumansCells
  111. Laussen PC, Murphy JA, Zurakowski D, Sullivan LJ, McGowan FX, Demaso DR. Bispectral index monitoring in children undergoing mild hypothermic cardiopulmonary bypass. Paediatr Anaesth. 2001; 11(5):567-73. PMID: 11696121.
    Citations: 2     Fields:    Translation:Humans
  112. Takeuchi K, McGowan FX, Moran AM, Zurakowski D, Mayer JE, Jonas RA, del Nido PJ. Surgical outcome of double-outlet right ventricle with subpulmonary VSD. Ann Thorac Surg. 2001 Jan; 71(1):49-52; discussion 52-3. PMID: 11216809.
    Citations: 3     Fields:    Translation:Humans
  113. Takeuchi K, del Nido PJ, Poutias DN, Cowan DB, Munakata M, McGowan FX. Vesnarinone restores contractility and calcium handling in early endotoxemia. Circulation. 2000 Nov 07; 102(19 Suppl 3):III365-9. PMID: 11082415.
    Citations: 2     Fields:    Translation:AnimalsCells
  114. Sethna NF, Sullivan L, Retik A, McGowan FX, Zurakowski D. Efficacy of simulated epinephrine-containing epidural test dose after intravenous atropine during isoflurane anesthesia in children. Reg Anesth Pain Med. 2000 Nov-Dec; 25(6):566-72. PMID: 11097662.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  115. Baker CM, McGowan FX, Keane JF, Lock JE. Pulmonary artery trauma due to balloon dilation: recognition, avoidance and management. J Am Coll Cardiol. 2000 Nov 01; 36(5):1684-90. PMID: 11079677.
    Citations: 2     Fields:    Translation:Humans
  116. Odegard KC, Kirse DJ, del Nido PJ, Laussen PC, Casta A, Booke J, Kenna MA, McGowan FX. Intraoperative recurrent laryngeal nerve monitoring during video-assisted throracoscopic surgery for patent ductus arteriosus. J Cardiothorac Vasc Anesth. 2000 Oct; 14(5):562-4. PMID: 11052439.
    Citations: 2     Fields:    Translation:Humans
  117. Casta A, Gruber EM, Laussen PC, McGowan FX, Odegard KC, Zurakowski D, Hansen DD. Parameters associated with perioperative baffle fenestration closure in the Fontan operation. J Cardiothorac Vasc Anesth. 2000 Oct; 14(5):553-6. PMID: 11052437.
    Citations: 1     Fields:    Translation:Humans
  118. Satou GM, McGowan FX, Colan SD. Left atrial compression from severe aortic root dilation and scoliosis. Heart Dis. 2000 Sep-Oct; 2(5):340-1. PMID: 11728279.
    Citations:    Fields:    Translation:Humans
  119. Cowan DB, Poutias DN, Del Nido PJ, McGowan FX. CD14-independent activation of cardiomyocyte signal transduction by bacterial endotoxin. . 2000 Aug; 279(2):H619-29. PMID: 10924061.
    Citations: 9     Translation:AnimalsCells
  120. Steven JM, McGowan FX. Neuraxial blockade for pediatric cardiac surgery: lessons yet to be learned. Anesth Analg. 2000 May; 90(5):1011-3. PMID: 10781444.
    Citations: 1     Fields:    Translation:Humans
  121. Laussen PC, Bichell DP, McGowan FX, Zurakowski D, DeMaso DR, del Nido PJ. Postoperative recovery in children after minimum versus full-length sternotomy. Ann Thorac Surg. 2000 Feb; 69(2):591-6. PMID: 10735704.
    Citations: 3     Fields:    Translation:Humans
  122. Friehs I, Moran AM, Stamm C, Colan SD, Takeuchi K, Cao-Danh H, Rader CM, McGowan FX, del Nido PJ. Impaired glucose transporter activity in pressure-overload hypertrophy is an early indicator of progression to failure. Circulation. 1999 Nov 09; 100(19 Suppl):II187-93. PMID: 10567302.
    Citations: 17     Fields:    Translation:Animals
  123. McGowan FX, Laussen PC. Con: transesophageal echocardiography should not be used routinely for pediatric open cardiac surgery. J Cardiothorac Vasc Anesth. 1999 Oct; 13(5):632-4. PMID: 10527238.
    Citations:    Fields:    Translation:Humans
  124. Takeuchi K, Cao-Danh H, Kawai A, Ohkado A, Konishi H, McGowan FX, del Nido PJ. Prolonged preservation of the blood-perfused canine heart with glycolysis-promoting solution. Ann Thorac Surg. 1999 Sep; 68(3):903-7. PMID: 10509981.
    Citations: 2     Fields:    Translation:AnimalsCells
  125. Takeuchi K, del Nido PJ, Ibrahim AE, Poutias DN, Glynn P, Cao-Danh H, Cowan DB, McGowan FX. Increased myocardial calcium cycling and reduced myofilament calcium sensitivity in early endotoxemia. Surgery. 1999 Aug; 126(2):231-8. PMID: 10455889.
    Citations: 4     Fields:    Translation:AnimalsCells
  126. Takeuchi K, del Nido PJ, Ibrahim AE, Cao-Danh H, Friehs I, Glynn P, Poutias D, Cowan DB, McGowan FX. Vesnarinone and amrinone reduce the systemic inflammatory response syndrome. J Thorac Cardiovasc Surg. 1999 Feb; 117(2):375-82. PMID: 9918980.
    Citations: 3     Fields:    Translation:AnimalsCells
  127. Takeuchi K, McGowan FX, Glynn P, Moran AM, Rader CM, Cao-Danh H, del Nido PJ. Glucose transporter upregulation improves ischemic tolerance in hypertrophied failing heart. Circulation. 1998 Nov 10; 98(19 Suppl):II234-9; discussion II240-1. PMID: 9852908.
    Citations: 9     Fields:    Translation:Animals
  128. Luppi P, Rudert WA, Zanone MM, Stassi G, Trucco G, Finegold D, Boyle GJ, Del Nido P, McGowan FX, Trucco M. Idiopathic dilated cardiomyopathy: a superantigen-driven autoimmune disease. Circulation. 1998 Aug 25; 98(8):777-85. PMID: 9727548.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  129. Takeuchi K, Cao-Danh H, Friehs I, Glynn P, D'Agostino D, Simplaceanu E, McGowan FX, del Nido PJ. Administration of fructose 1,6-diphosphate during early reperfusion significantly improves recovery of contractile function in the postischemic heart. J Thorac Cardiovasc Surg. 1998 Aug; 116(2):335-43. PMID: 9699588.
    Citations: 12     Fields:    Translation:Animals
  130. Montenegro LM, Ward A, McGowan FX, Davis PJ. New directions in perioperative management for pediatric solid organ transplantation. J Cardiothorac Vasc Anesth. 1998 Aug; 12(4):457-72. PMID: 9713740.
    Citations:    Fields:    Translation:Humans
  131. Friehs I, Cao-Danh H, Takahashi S, Buenaventura P, Glynn P, McGowan FX, del Nido PJ. Adenosine prevents protein kinase C activation during hypothermic ischemia. Circulation. 1997 Nov 04; 96(9 Suppl):II-221-5; discussion II-225-6. PMID: 9386102.
    Citations: 2     Fields:    Translation:AnimalsCells
  132. Zünd G, Uezono S, Stahl GL, Dzus AL, McGowan FX, Hickey PR, Colgan SP. Hypoxia enhances induction of endothelial ICAM-1: role for metabolic acidosis and proteasomes. Am J Physiol. 1997 11; 273(5):C1571-80. PMID: 9374642.
    Citations: 28     Fields:    Translation:HumansCells
  133. Patel RI, Davis PJ, Orr RJ, Ferrari LR, Rimar S, Hannallah RS, Cohen IT, Colingo K, Donlon JV, Haberkern CM, McGowan FX, Prillaman BA, Parasuraman TV, Creed MR. Single-dose ondansetron prevents postoperative vomiting in pediatric outpatients. Anesth Analg. 1997 Sep; 85(3):538-45. PMID: 9296406.
    Citations: 7     Fields:    Translation:HumansCTClinical Trials
  134. Davis PJ, Lerman J, Suresh S, McGowan FX, Coté CJ, Landsman I, Henson LG. A randomized multicenter study of remifentanil compared with alfentanil, isoflurane, or propofol in anesthetized pediatric patients undergoing elective strabismus surgery. Anesth Analg. 1997 May; 84(5):982-9. PMID: 9141919.
    Citations: 13     Fields:    Translation:HumansCTClinical Trials
  135. Luss H, Li RK, Shapiro RA, Tzeng E, McGowan FX, Yoneyama T, Hatakeyama K, Geller DA, Mickle DA, Simmons RL, Billiar TR. Dedifferentiated human ventricular cardiac myocytes express inducible nitric oxide synthase mRNA but not protein in response to IL-1, TNF, IFNgamma, and LPS. J Mol Cell Cardiol. 1997 Apr; 29(4):1153-65. PMID: 9160867.
    Citations: 3     Fields:    Translation:HumansCells
  136. Wilson AS, Stiller RL, Davis PJ, Fedel G, Chakravorti S, Israel BA, McGowan FX. Fentanyl and alfentanil plasma protein binding in preterm and term neonates. Anesth Analg. 1997 Feb; 84(2):315-8. PMID: 9024020.
    Citations: 10     Fields:    Translation:HumansCells
  137. Ter-Akopian GM, Hamilton JH, Oganessian YT, Daniel AV, Kormicki J, Ramayya AV, Popeko GS, Babu BR, Lu Q, Butler-Moore K, Ma W, Cwiok S, Nazarewicz W, Deng JK, Shi D, Kliman J, Morhac M, Cole JD, Aryaeinejad R, Johnson NR, Lee IY, McGowan FK, Saladin JX. New Spontaneous Fission Mode for 252Cf: Indication of Hyperdeformed 144,145,146Ba at Scission. Phys Rev Lett. 1996 Jul 01; 77(1):32-35. PMID: 10061764.
    Citations:    Fields:    
  138. Bindra KS, Hua PF, Babu BR, Baktash C, Barreto J, Cullen DM, Davids CN, Deng JK, Garrett JD, Halbert ML, Hamilton JH, Johnson NR, Kirov A, Kormicki J, Lee IY, Ma WC, McGowan FK, Ramayya AV, Sarantites DG, Soramel F, Winchell D. Reply to "Comment on 'Prolate-oblate band mixing and new bands in 182Hg' " Phys Rev C Nucl Phys. 1996 Jun; 53(6):3165. PMID: 9971308.
    Citations:    
  139. Jin H, Riedinger LL, Bingham CR, Carpenter MP, Janzen VP, Yu C, Zhou L, Semmes PB, Zhang J, Riley MA, Baktash C, Halbert ML, Johnson NR, Lee IY, McGowan FK. Effects of intruder states in 179Ir. Phys Rev C Nucl Phys. 1996 May; 53(5):2106-2125. PMID: 9971186.
    Citations:    
  140. Petrovici A, Schmid KW, Faessler A, Pantelica D, Negoita F, Babu BR, Ramayya AV, Hamilton JH, Kormicki J, Chaturvedi L, Ma WC, Zhu SJ, Johnson NR, Lee IY, Baktash C, McGowan FK, Halbert ML, Riley M, Cole JD. High spin states in 68As: Experiment and theory. Phys Rev C Nucl Phys. 1996 May; 53(5):2134-2141. PMID: 9971188.
    Citations:    
  141. Johnson NR, McGowan FK, Winchell DF, Baktash C, Garrett JD, Lee IY, Wells JC, Chaturvedi L, Gao WB, Ma WC, Pilotte S, Yu C. Evolution of collectivity to very high spins in 160Yb. Phys Rev C Nucl Phys. 1996 Feb; 53(2):671-678. PMID: 9970985.
    Citations:    
  142. Bellamy R, Safar P, Tisherman SA, Basford R, Bruttig SP, Capone A, Dubick MA, Ernster L, Hattler BG, Hochachka P, Klain M, Kochanek PM, Kofke WA, Lancaster JR, McGowan FX, Oeltgen PR, Severinghaus JW, Taylor MJ, Zar H. Suspended animation for delayed resuscitation. Crit Care Med. 1996 Feb; 24(2 Suppl):S24-47. PMID: 8608704.
    Citations: 16     Fields:    Translation:HumansAnimals
  143. Hickey PR, McGowan FX. Adhesion molecules and inflammation: the next targets for perioperative organ protection? Anesth Analg. 1995 Dec; 81(6):1123-4. PMID: 7486091.
    Citations:    Fields:    Translation:HumansAnimals
  144. Buenaventura P, Cao-Danh H, Glynn P, Takeuchi K, Takahashi S, Simplaceanu E, McGowan FX, del Nido PJ. Protein kinase C activation in the heart: effects on calcium and contractile proteins. Ann Thorac Surg. 1995 Dec; 60(6 Suppl):S505-8. PMID: 8604920.
    Citations: 2     Fields:    Translation:AnimalsCells
  145. Davis PJ, McGowan FX, Landsman I, Maloney K, Hoffmann P. Effect of antiemetic therapy on recovery and hospital discharge time. A double-blind assessment of ondansetron, droperidol, and placebo in pediatric patients undergoing ambulatory surgery. Anesthesiology. 1995 Nov; 83(5):956-60. PMID: 7486180.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  146. Takeuchi K, Buenaventura P, Cao-Danh H, Glynn P, Simplaceanu E, McGowan FX, del Nido PJ. Improved protection of the hypertrophied left ventricle by histidine-containing cardioplegia. Circulation. 1995 Nov 01; 92(9 Suppl):II395-9. PMID: 7586444.
    Citations: 3     Fields:    Translation:AnimalsCells
  147. Luss H, Watkins SC, Freeswick PD, Imro AK, Nussler AK, Billiar TR, Simmons RL, del Nido PJ, McGowan FX. Characterization of inducible nitric oxide synthase expression in endotoxemic rat cardiac myocytes in vivo and following cytokine exposure in vitro. J Mol Cell Cardiol. 1995 Sep; 27(9):2015-29. PMID: 8523461.
    Citations: 14     Fields:    Translation:AnimalsCells
  148. Lu QH, Butler-Moore K, Zhu SJ, Hamilton JH, Ramayya AV, Oberacker VE, Ma WC, Babu BR, Deng JK, Kormicki J, Cole JD, Aryaeinejad R, Dardenne YX, Drigert M, Peker LK, Rasmussen JO, Stoyer MA, Chu SY, Gregorich KE, Lee IY, Mohar MF, Nitschke JM, Johnson NR, McGowan FK, Ter-Akopian GM, Oganessian YT, Gupta JB. Structure of 108,110,112Ru: Identical bands in 108,110Ru. Phys Rev C Nucl Phys. 1995 Sep; 52(3):1348-1354. PMID: 9970639.
    Citations:    
  149. Takeuchi K, McGowan FX, Danh HC, Glynn P, Simplaceanu E, del Nido PJ. Direct detrimental effects of L-arginine upon ischemia--reperfusion injury to myocardium. J Mol Cell Cardiol. 1995 Jul; 27(7):1405-14. PMID: 7473786.
    Citations: 4     Fields:    Translation:AnimalsCells
  150. Winchell DF, Lee IY, Baktash C, Garrett JD, Halbert ML, Johnson NR, McGowan FK, Yu CH. Search for two-phonon gamma vibrational states in 164Dy. Phys Rev C Nucl Phys. 1995 Jun; 51(6):2952-2958. PMID: 9970396.
    Citations:    
  151. Riley MA, Brown TB, Johnson NR, Akovali YA, Baktash C, Halbert ML, Hensley DC, Lee IY, McGowan FK, Virtanen A, Whitley ME, Simpson J, Chaturvedi L, Courtney LH, Janzen VP, Riedinger LL, Bengtsson T. Alignments, shape changes, and band terminations in 157Tm. Phys Rev C Nucl Phys. 1995 Mar; 51(3):1234-1246. PMID: 9970172.
    Citations:    
  152. McGowan FX, Davis PJ, Siewers RD, del Nido PJ. Coronary vasoconstriction mediated by endothelin-1 in neonates. Reversal by nitroglycerin. J Thorac Cardiovasc Surg. 1995 Jan; 109(1):88-97; discussion 97-8. PMID: 7815811.
    Citations: 1     Fields:    Translation:HumansAnimals
  153. Davis PJ, Tome JA, McGowan FX, Cohen IT, Latta K, Felder H. Preanesthetic medication with intranasal midazolam for brief pediatric surgical procedures. Effect on recovery and hospital discharge times. Anesthesiology. 1995 Jan; 82(1):2-5. PMID: 7832301.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  154. Bindra KS, Hua PF, Babu BR, Baktash C, Barreto J, Cullen DM, Davids CN, Deng JK, Garrett JD, Halbert ML, Hamilton JH, Johnson NR, Kirov A, Kormicki J, Lee IY, Ma WC, McGowan FK, Ramayya AV, Sarantites DG, Soramel F, Winchell D. Prolate-oblate band mixing and new bands in 182Hg. Phys Rev C Nucl Phys. 1995 Jan; 51(1):401-404. PMID: 9970075.
    Citations:    
  155. McGowan FX, Davis PJ, del Nido PJ, Sobek M, Allen JW, Downing SE. Endothelium-dependent regulation of coronary tone in the neonatal pig. Anesth Analg. 1994 Dec; 79(6):1094-101. PMID: 7978431.
    Citations: 2     Fields:    Translation:Animals
  156. Lee IY, Baktash C, Cullen DM, Garrett JD, Johnson NR, McGowan FK, Winchell DF, Yu CH. Lifetimes of low-spin states in the superdeformed band of 192Hg. Phys Rev C Nucl Phys. 1994 Nov; 50(5):2602-2605. PMID: 9969949.
    Citations:    
  157. McGowan FX, Cao-Danh H, Takeuchi K, Davis PJ, del Nido PJ. Prolonged neonatal myocardial preservation with a highly buffered low-calcium solution. J Thorac Cardiovasc Surg. 1994 Oct; 108(4):772-9. PMID: 7934115.
    Citations: 2     Fields:    Translation:AnimalsCells
  158. Ter-Akopian GM, Hamilton JH, Oganessian YT, Kormicki J, Popeko GS, Daniel AV, Ramayya AV, Lu Q, Butler-Moore K, Ma W, Deng JK, Shi D, Kliman J, Polhorshy V, Morhac M, Greiner W, Sandelescu A, Cole JD, Aryaeinejad R, Johnson NR, Lee IY, McGowan FK. Neutron multiplicities and yields of correlated Zr-Ce and Mo-Ba fragment pairs in spontaneous fission of 252Cf. Phys Rev Lett. 1994 Sep 12; 73(11):1477-1480. PMID: 10056803.
    Citations:    Fields:    
  159. Baktash C, Abenante V, Griffin HC, Halbert ML, Hensley DC, Johnson NR, Lee IY, McGowan FK, Riley MA, Sarantites DG, Semkow TM, Stracener DW, Virtanen A. High spin states of 84Sr. Phys Rev C Nucl Phys. 1994 Jun; 49(6):3309-3311. PMID: 9969613.
    Citations: 1     
  160. Davis PJ, Cohen IT, McGowan FX, Latta K. Recovery characteristics of desflurane versus halothane for maintenance of anesthesia in pediatric ambulatory patients. Anesthesiology. 1994 Feb; 80(2):298-302. PMID: 8311312.
    Citations: 17     Fields:    Translation:HumansCTClinical Trials
  161. Pilotte S, Yu C, Jin HQ, Lewis JM, Riedinger LL, Liang Y, Janssens RV, Carpenter MP, Khoo TL, Lauritsen T, Soramel F, Bearden IG, Baktash C, Garrett JD, Johnson NR, Lee IY, McGowan FK. Superdeformed bands in 191Tl. Phys Rev C Nucl Phys. 1994 Feb; 49(2):718-724. PMID: 9969277.
    Citations:    
  162. McGowan FX, Takeuchi K, del Nido PJ, Davis PJ, Lancaster JR, Hattler BG. Myocardial effects of interleukin-2. Transplant Proc. 1994 Feb; 26(1):209-10. PMID: 7509092.
    Citations: 2     Fields:    Translation:Animals
  163. McGowan FX, Ikegami M, del Nido PJ, Motoyama EK, Kurland G, Davis PJ, Siewers RD. Cardiopulmonary bypass significantly reduces surfactant activity in children. J Thorac Cardiovasc Surg. 1993 Dec; 106(6):968-77. PMID: 8246579.
    Citations: 6     Fields:    Translation:HumansCells
  164. Woelfel SK, Brandom BW, McGowan FX, Cook DR. Clinical pharmacology of mivacurium in pediatric patients less than off years old during nitrous oxide-halothane anesthesia. Anesth Analg. 1993 Oct; 77(4):713-20. PMID: 8214654.
    Citations: 2     Fields:    Translation:HumansCells
  165. Aryaeinejad R, Cole JD, Greenwood RC, Harrill SS, Lohstreter NP, Butler-Moore K, Zhu S, Hamilton JH, Ramayya AV, Zhao X, Ma WC, Kormicki J, Deng JK, Gao WB, Lee IY, Johnson NR, McGowan FK, Ter-Akopian G, Oganessian Y. Band crossing observed in neutron-rich Pd isotopes via spontaneous fission of 252Cf. Phys Rev C Nucl Phys. 1993 Aug; 48(2):566-573. PMID: 9968863.
    Citations:    
  166. Cullen DM, Lee IY, Baktash C, Garrett JD, Johnson NR, McGowan FK, Winchell DF. X-ray yields of superdeformed states in 193Hg. Phys Rev C Nucl Phys. 1993 Mar; 47(3):1298-1301. PMID: 9968564.
    Citations:    
  167. Ma WC, Hamilton JH, Ramayya AV, Chaturvedi L, Deng JK, Gao WB, Jiang YR, Kormicki J, Zhao XW, Johnson NR, Garrett JD, Lee IY, Baktash C, McGowan FK, Nazarewicz W, Wyss R. First evidence for states in Hg nuclei with deformations between normal and super deformation. Phys Rev C Nucl Phys. 1993 Jan; 47(1):R5-R8. PMID: 9968457.
    Citations:    
  168. McGowan FX, Kenna MA, Fleming JA, O'Connor T. Adenotonsillectomy for upper airway obstruction carries increased risk in children with a history of prematurity. Pediatr Pulmonol. 1992 Aug; 13(4):222-6. PMID: 1523032.
    Citations: 4     Fields:    Translation:Humans
  169. McGowan FX, Lee FA, Chen V, Downing SE. Oxidative metabolism and mechanical function in reperfused neonatal pig heart. J Mol Cell Cardiol. 1992 Aug; 24(8):831-40. PMID: 1433313.
    Citations: 1     Fields:    Translation:AnimalsCells
  170. Lee IY, Baktash C, Beene JR, Halbert ML, Hensley DC, Johnson NR, McGowan FK, Riley MA, Sarantites DG. Quantitative studies of continuum gamma-ray correlations in 170Hf. Phys Rev C Nucl Phys. 1992 Aug; 46(2):597-603. PMID: 9968155.
    Citations:    
  171. McGowan FX. Cardiovascular and airway interactions. Int Anesthesiol Clin. 1992; 30(4):21-44. PMID: 1468806.
    Citations: 2     Fields:    Translation:Humans
  172. Gao WB, Lee IY, Baktash C, Wyss R, Hamilton JH, Steele CM, Yu CH, Johnson NR, McGowan FK. High spin spectroscopy and lifetime measurements in 169Hf. Phys Rev C Nucl Phys. 1991 Oct; 44(4):1380-1396. PMID: 9967542.
    Citations:    
  173. Chaturvedi L, Zhao X, Ramayya AV, Hamilton JH, Kormicki J, Zhu S, Girit C, Xie H, Gao W, Jiang Y, Petrovici A, Schmid KW, Faessler A, Johnson NR, Baktash C, Lee IY, McGowan FK, Halbert ML, Riley MA, McNeill JH, Kortelahti MO, Cole JD, Piercey RB, Jin HQ. Tests of microscopic calculations of multiple band structures and large deformations in 68Ge and 72Se. Phys Rev C Nucl Phys. 1991 Jun; 43(6):2541-2545. PMID: 9967313.
    Citations:    
  174. Hansen DD, Haberkern CM, Jonas RA, Davis PJ, McGowan FX. Case 1--1991. Tracheal stenosis in an infant with Down's syndrome and complex congenital heart defect. J Cardiothorac Vasc Anesth. 1991 Feb; 5(1):81-5. PMID: 1831054.
    Citations:    Fields:    Translation:Humans
  175. Hellenbrand WE, Fahey JT, McGowan FX, Weltin GG, Kleinman CS. Transesophageal echocardiographic guidance of transcatheter closure of atrial septal defect. Am J Cardiol. 1990 Jul 15; 66(2):207-13. PMID: 2371953.
    Citations: 20     Fields:    Translation:Humans
  176. Sarantites DG, Baktash C, Nicolis NG, Garcia-Bermudez G, Abenante V, Beene JR, Johnson NR, Halbert ML, Hensley DC, McGowan FK, Griffin HC, Lee IY, Majka Z, Riley MA, Semkow TM, Stracener DW, Virtanen A. Nuclear-structure effects in proton evaporation spectra. Phys Rev Lett. 1990 Apr 30; 64(18):2129-2132. PMID: 10041591.
    Citations:    Fields:    
  177. Wells JC, Johnson NR, Baktash C, Lee IY, McGowan FK, Riley MA, Virtanen A, Dudek J. High-spin studies of 172,173Os: Complex alignment mechanism. Phys Rev C Nucl Phys. 1989 Aug; 40(2):725-741. PMID: 9966037.
    Citations:    
  178. Riley MA, Akovali YA, Baktash C, Halbert ML, Hensley DC, Johnson NR, Lee IY, McGowan FK, Virtanen A, Courtney LH, Janzen VP, Riedinger LL, Chaturvedi L, Simpson J. Irregularities at high spin in the odd-odd nucleus 158Tm. Phys Rev C Nucl Phys. 1989 Jan; 39(1):291-294. PMID: 9955199.
    Citations: