Harvard Catalyst Profiles

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Robert John D'Amato, Ph.D., M.D.


Mapping Quantitative Trait Loci for Angiogenic Susceptibility in Mice
Summer, 06/04/07 - 07/27/07

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01EY012726 (D'AMATO, ROBERT J) Aug 1, 1999 - Jul 31, 2017
    Identification of Common Polymorphisms Affecting Angiogenesis
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Fu H, Siggs OM, Knight LS, Staffieri SE, Ruddle JB, Birsner AE, Collantes ER, Craig JE, Wiggs JL, D'Amato RJ. Thrombospondin 1 missense alleles induce extracellular matrix protein aggregation and TM dysfunction in congenital glaucoma. J Clin Invest. 2022 12 01; 132(23). PMID: 36453543; PMCID: PMC9711877.
    Citations:    Fields:    Translation:Animals
  2. Peng DW, Lan CL, Dong LQ, Jiang MX, Xiao H, D'Amato RJ, Chi ZL. Anti-angiogenic properties of microRNA-29a in preclinical ocular models. Proc Natl Acad Sci U S A. 2022 11 08; 119(45):e2204795119. PMID: 36322719; PMCID: PMC9659377.
    Citations: 1     Fields:    Translation:Animals
  3. Adini A, Adini I, Grad E, Tal Y, Danenberg HD, Kang PM, Matthews BD, D'Amato RJ. The Prominin-1-Derived Peptide Improves Cardiac Function Following Ischemia. Int J Mol Sci. 2021 May 13; 22(10). PMID: 34068392.
    Citations:    Fields:    Translation:AnimalsCells
  4. Khajavi M, Zhou Y, Schiffer AJ, Bazinet L, Birsner AE, Zon L, D'Amato RJ. Identification of Basp1 as a novel angiogenesis-regulating gene by multi-model system studies. FASEB J. 2021 05; 35(5):e21404. PMID: 33899275; PMCID: PMC8218237.
    Citations:    Fields:    Translation:HumansAnimalsCells
  5. Steinberg E, Fluksman A, Zemmour C, Tischenko K, Karsch-Bluman A, Brill-Karniely Y, Birsner AE, D'Amato RJ, Benny O. Low dose amiodarone reduces tumor growth and angiogenesis. Sci Rep. 2020 10 22; 10(1):18034. PMID: 33093573.
    Citations:    Fields:    Translation:HumansAnimalsCells
  6. Bai J, Khajavi M, Sui L, Fu H, Tarakkad Krishnaji S, Birsner AE, Bazinet L, Kamm RD, D'Amato RJ. Angiogenic responses in a 3D micro-engineered environment of primary endothelial cells and pericytes. Angiogenesis. 2021 02; 24(1):111-127. PMID: 32955682.
    Citations: 14     Fields:    Translation:AnimalsCells
  7. Bai J, Fu H, Bazinet L, Birsner AE, D'Amato RJ. A Method for Developing Novel 3D Cornea-on-a-Chip Using Primary Murine Corneal Epithelial and Endothelial Cells. Front Pharmacol. 2020; 11:453. PMID: 32410987; PMCID: PMC7198819.
    Citations: 3     
  8. Guan JT, Li XX, Peng DW, Zhang WM, Qu J, Lu F, D'Amato RJ, Chi ZL. MicroRNA-18a-5p Administration Suppresses Retinal Neovascularization by Targeting FGF1 and HIF1A. Front Pharmacol. 2020; 11:276. PMID: 32210827; PMCID: PMC7076186.
    Citations: 4     
  9. Chi ZL, Adini A, Birsner AE, Bazinet L, Akula JD, D'Amato RJ. PR1P ameliorates neurodegeneration through activation of VEGF signaling pathway and remodeling of the extracellular environment. Neuropharmacology. 2019 04; 148:96-106. PMID: 30594697.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  10. Wu H, Rahman HNA, Dong Y, Liu X, Lee Y, Wen A, To KH, Xiao L, Birsner AE, Bazinet L, Wong S, Song K, Brophy ML, Mahamud MR, Chang B, Cai X, Pasula S, Kwak S, Yang W, Bischoff J, Xu J, Bielenberg DR, Dixon JB, D'Amato RJ, Srinivasan RS, Chen H. Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes. J Clin Invest. 2018 08 31; 128(9):4025-4043. PMID: 30102256; PMCID: PMC6118634.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  11. Khajavi M, Zhou Y, Birsner AE, Bazinet L, Rosa Di Sant A, Schiffer AJ, Rogers MS, Krishnaji ST, Hu B, Nguyen V, Zon L, D'Amato RJ. Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice. PLoS Genet. 2017 Jun; 13(6):e1006848. PMID: 28617813; PMCID: PMC5491319.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  12. Adini A, Adini I, Chi ZL, Derda R, Birsner AE, Matthews BD, D'Amato RJ. A novel strategy to enhance angiogenesis in vivo using the small VEGF-binding peptide PR1P. Angiogenesis. 2017 Aug; 20(3):399-408. PMID: 28397127.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  13. Abramov E, Cassiola F, Schwob O, Karsh-Bluman A, Shapero M, Ellis J, Luyindula D, Adini I, D'Amato RJ, Benny O. Cellular mechanism of oral absorption of solidified polymer micelles. Nanomedicine. 2015 Nov; 11(8):1993-2002. PMID: 26247432.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  14. Adini I, Adini A, Bazinet L, Watnick RS, Bielenberg DR, D'Amato RJ. Melanocyte pigmentation inversely correlates with MCP-1 production and angiogenesis-inducing potential. FASEB J. 2015 Feb; 29(2):662-70. PMID: 25406462; PMCID: PMC4314224.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  15. Hasegawa E, Sweigard H, Husain D, Olivares AM, Chang B, Smith KE, Birsner AE, D'Amato RJ, Michaud NA, Han Y, Vavvas DG, Miller JW, Haider NB, Connor KM. Characterization of a spontaneous retinal neovascular mouse model. PLoS One. 2014; 9(9):e106507. PMID: 25188381.
    Citations: 20     Fields:    Translation:Animals
  16. Birsner AE, Benny O, D'Amato RJ. The corneal micropocket assay: a model of angiogenesis in the mouse eye. J Vis Exp. 2014 Aug 16; (90). PMID: 25177860.
    Citations: 12     Fields:    Translation:Animals
  17. Adini I, Ghosh K, Adini A, Chi ZL, Yoshimura T, Benny O, Connor KM, Rogers MS, Bazinet L, Birsner AE, Bielenberg DR, D'Amato RJ. Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment. J Clin Invest. 2014 Jan; 124(1):425-36. PMID: 24355922; PMCID: PMC3871226.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  18. D'Amato RJ, Lentzsch S, Rogers MS. Pomalidomide is strongly antiangiogenic and teratogenic in relevant animal models. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):E4818. PMID: 24302770.
    Citations: 3     Fields:    Translation:AnimalsCells
  19. Yoshimura T, Benny O, Bazinet L, D'Amato RJ. Suppression of autoimmune retinal inflammation by an antiangiogenic drug. PLoS One. 2013; 8(6):e66219. PMID: 23785488.
    Citations: 3     Fields:    Translation:AnimalsCells
  20. Rogers MS, Adini I, McBride AF, Birsner AE, D'Amato RJ. The albino mutation of tyrosinase alters ocular angiogenic responsiveness. Angiogenesis. 2013 Jul; 16(3):639-46. PMID: 23423728.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  21. Xu H, Zhang T, Man GC, May KE, Becker CM, Davis TN, Kung AL, Birsner AE, D'Amato RJ, Wong AW, Wang CC. Vascular endothelial growth factor C is increased in endometrium and promotes endothelial functions, vascular permeability and angiogenesis and growth of endometriosis. Angiogenesis. 2013 Jul; 16(3):541-51. PMID: 23334337.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  22. Adini A, Adini I, Ghosh K, Benny O, Pravda E, Hu R, Luyindula D, D'Amato RJ. The stem cell marker prominin-1/CD133 interacts with vascular endothelial growth factor and potentiates its action. Angiogenesis. 2013 Apr; 16(2):405-16. PMID: 23150059.
    Citations: 19     Fields:    Translation:HumansCells
  23. Rogers MS, D'Amato RJ. Common polymorphisms in angiogenesis. Cold Spring Harb Perspect Med. 2012 Nov 01; 2(11). PMID: 23125197.
    Citations: 7     Fields:    Translation:HumansAnimals
  24. Rogers MS, Boyartchuk V, Rohan RM, Birsner AE, Dietrich WF, D'Amato RJ. The classical pink-eyed dilution mutation affects angiogenic responsiveness. PLoS One. 2012; 7(5):e35237. PMID: 22615734.
    Citations: 5     Fields:    Translation:Animals
  25. Peterson JE, Zurakowski D, Italiano JE, Michel LV, Connors S, Oenick M, D'Amato RJ, Klement GL, Folkman J. VEGF, PF4 and PDGF are elevated in platelets of colorectal cancer patients. Angiogenesis. 2012 Jun; 15(2):265-73. PMID: 22402885.
    Citations: 90     Fields:    Translation:HumansCTClinical Trials
  26. Cao Y, Arbiser J, D'Amato RJ, D'Amore PA, Ingber DE, Kerbel R, Klagsbrun M, Lim S, Moses MA, Zetter B, Dvorak H, Langer R. Forty-year journey of angiogenesis translational research. Sci Transl Med. 2011 Dec 21; 3(114):114rv3. PMID: 22190240.
    Citations: 94     Fields:    Translation:Humans
  27. Jakobiec FA, Zakka FR, D'Amato R, Deangelis MM, Walton DS, Rao RC. Unilateral sporadic retinal dysplasia: results of histopathologic, immunohistochemical, chromosomal, genetic, and VEGF-A analyses. J AAPOS. 2011 Dec; 15(6):579-86. PMID: 22153404.
    Citations: 1     Fields:    Translation:Humans
  28. Erba P, Miele LF, Adini A, Ackermann M, Lamarche JM, Orgill BD, D'Amato RJ, Konerding MA, Mentzer SJ, Orgill DP. A morphometric study of mechanotransductively induced dermal neovascularization. Plast Reconstr Surg. 2011 Oct; 128(4):288e-299e. PMID: 21921741; PMCID: PMC3350091.
    Citations: 7     Fields:    Translation:AnimalsCells
  29. Xu H, Becker CM, Lui WT, Chu CY, Davis TN, Kung AL, Birsner AE, D'Amato RJ, Wai Man GC, Wang CC. Green tea epigallocatechin-3-gallate inhibits angiogenesis and suppresses vascular endothelial growth factor C/vascular endothelial growth factor receptor 2 expression and signaling in experimental endometriosis in vivo. Fertil Steril. 2011 Oct; 96(4):1021-8. PMID: 21821246.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  30. Becker CM, Beaudry P, Funakoshi T, Benny O, Zaslavsky A, Zurakowski D, Folkman J, D'Amato RJ, Ryeom S. Circulating endothelial progenitor cells are up-regulated in a mouse model of endometriosis. Am J Pathol. 2011 Apr; 178(4):1782-91. PMID: 21435458; PMCID: PMC3070089.
    Citations: 27     Fields:    Translation:AnimalsCells
  31. Erba P, Ogawa R, Ackermann M, Adini A, Miele LF, Dastouri P, Helm D, Mentzer SJ, D'Amato RJ, Murphy GF, Konerding MA, Orgill DP. Angiogenesis in wounds treated by microdeformational wound therapy. Ann Surg. 2011 Feb; 253(2):402-9. PMID: 21217515; PMCID: PMC3403722.
    Citations: 56     Fields:    Translation:Animals
  32. Benny O, Nakai K, Yoshimura T, Bazinet L, Akula JD, Nakao S, Hafezi-Moghadam A, Panigrahy D, Pakneshan P, D'Amato RJ. Broad spectrum antiangiogenic treatment for ocular neovascular diseases. PLoS One. 2010 Sep 01; 5(9). PMID: 20824139.
    Citations: 10     Fields:    Translation:HumansAnimals
  33. Fainaru O, Almog N, Yung CW, Nakai K, Montoya-Zavala M, Abdollahi A, D'Amato R, Ingber DE. Tumor growth and angiogenesis are dependent on the presence of immature dendritic cells. FASEB J. 2010 May; 24(5):1411-8. PMID: 20008545.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  34. Nakai K, Rogers MS, Baba T, Funakoshi T, Birsner AE, Luyindula DS, D'Amato RJ. Genetic loci that control the size of laser-induced choroidal neovascularization. FASEB J. 2009 Jul; 23(7):2235-43. PMID: 19237505.
    Citations: 11     Fields:    Translation:AnimalsCells
  35. Adini A, Fainaru O, Udagawa T, Connor KM, Folkman J, D'Amato RJ. Matrigel cytometry: a novel method for quantifying angiogenesis in vivo. J Immunol Methods. 2009 Mar 15; 342(1-2):78-81. PMID: 19109967.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  36. Fainaru O, Adini I, Benny O, Bazinet L, Pravda E, D'Amato R, Folkman J. Doxycycline induces membrane expression of VE-cadherin on endothelial cells and prevents vascular hyperpermeability. FASEB J. 2008 Oct; 22(10):3728-35. PMID: 18606869.
    Citations: 31     Fields:    Translation:AnimalsCells
  37. Benny O, Fainaru O, Adini A, Cassiola F, Bazinet L, Adini I, Pravda E, Nahmias Y, Koirala S, Corfas G, D'Amato RJ, Folkman J. An orally delivered small-molecule formulation with antiangiogenic and anticancer activity. Nat Biotechnol. 2008 Jul; 26(7):799-807. PMID: 18587385.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  38. Pakneshan P, Birsner AE, Adini I, Becker CM, D'Amato RJ. Differential suppression of vascular permeability and corneal angiogenesis by nonsteroidal anti-inflammatory drugs. Invest Ophthalmol Vis Sci. 2008 Sep; 49(9):3909-13. PMID: 18487370.
    Citations: 20     Fields:    Translation:Animals
  39. Nakai K, Fainaru O, Bazinet L, Pakneshan P, Benny O, Pravda E, Folkman J, D'Amato RJ. Dendritic cells augment choroidal neovascularization. Invest Ophthalmol Vis Sci. 2008 Aug; 49(8):3666-70. PMID: 18408184.
    Citations: 14     Fields:    Translation:AnimalsCells
  40. Becker CM, Rohwer N, Funakoshi T, Cramer T, Bernhardt W, Birsner A, Folkman J, D'Amato RJ. 2-methoxyestradiol inhibits hypoxia-inducible factor-1{alpha} and suppresses growth of lesions in a mouse model of endometriosis. Am J Pathol. 2008 Feb; 172(2):534-44. PMID: 18202195; PMCID: PMC2312351.
    Citations: 44     Fields:    Translation:Animals
  41. Rogers MS, Christensen KA, Birsner AE, Short SM, Wigelsworth DJ, Collier RJ, D'Amato RJ. Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth. Cancer Res. 2007 Oct 15; 67(20):9980-5. PMID: 17942931.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  42. Fainaru O, Adini A, Benny O, Adini I, Short S, Bazinet L, Nakai K, Pravda E, Hornstein MD, D'Amato RJ, Folkman J. Dendritic cells support angiogenesis and promote lesion growth in a murine model of endometriosis. FASEB J. 2008 Feb; 22(2):522-9. PMID: 17873101.
    Citations: 35     Fields:    Translation:AnimalsCells
  43. Becker CM, D'Amato RJ. Angiogenesis and antiangiogenic therapy in endometriosis. Microvasc Res. 2007 Sep-Nov; 74(2-3):121-30. PMID: 17574280.
    Citations: 36     Fields:    Translation:HumansAnimals
  44. Udagawa T, Birsner AE, Wood M, D'Amato RJ. Chronic suppression of angiogenesis following radiation exposure is independent of hematopoietic reconstitution. Cancer Res. 2007 Mar 01; 67(5):2040-5. PMID: 17332332.
    Citations: 16     Fields:    Translation:AnimalsCells
  45. Rogers MS, Birsner AE, D'Amato RJ. The mouse cornea micropocket angiogenesis assay. Nat Protoc. 2007; 2(10):2545-50. PMID: 17947997.
    Citations: 63     Fields:    Translation:Animals
  46. Funakoshi T, Birsner AE, D'Amato RJ. Antiangiogenic effect of oral 2-methoxyestradiol on choroidal neovascularization in mice. Exp Eye Res. 2006 Nov; 83(5):1102-7. PMID: 16828472.
    Citations: 9     Fields:    Translation:Animals
  47. Becker CM, Wright RD, Satchi-Fainaro R, Funakoshi T, Folkman J, Kung AL, D'Amato RJ. A novel noninvasive model of endometriosis for monitoring the efficacy of antiangiogenic therapy. Am J Pathol. 2006 Jun; 168(6):2074-84. PMID: 16723720; PMCID: PMC1606629.
    Citations: 24     Fields:    Translation:HumansAnimals
  48. Rogers MS, D'Amato RJ. The effect of genetic diversity on angiogenesis. Exp Cell Res. 2006 Mar 10; 312(5):561-74. PMID: 16321383.
    Citations: 20     Fields:    Translation:HumansAnimals
  49. Becker CM, Sampson DA, Short SM, Javaherian K, Folkman J, D'Amato RJ. Short synthetic endostatin peptides inhibit endothelial migration in vitro and endometriosis in a mouse model. Fertil Steril. 2006 Jan; 85(1):71-7. PMID: 16412733.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  50. Udagawa T, Puder M, Wood M, Schaefer BC, D'Amato RJ. Analysis of tumor-associated stromal cells using SCID GFP transgenic mice: contribution of local and bone marrow-derived host cells. FASEB J. 2006 Jan; 20(1):95-102. PMID: 16394272.
    Citations: 38     Fields:    Translation:AnimalsCells
  51. Becker CM, Sampson DA, Rupnick MA, Rohan RM, Efstathiou JA, Short SM, Taylor GA, Folkman J, D'Amato RJ. Endostatin inhibits the growth of endometriotic lesions but does not affect fertility. Fertil Steril. 2005 Oct; 84 Suppl 2:1144-55. PMID: 16210006.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  52. Wood M, Udagawa T, Hida Y, D'Amato RJ. X-linked dominant growth suppression of transplanted tumors in C57BL/6J-scid mice. Cancer Res. 2005 Jul 01; 65(13):5690-5. PMID: 15994943.
    Citations:    Fields:    Translation:HumansAnimalsCells
  53. Shaked Y, Bertolini F, Man S, Rogers MS, Cervi D, Foutz T, Rawn K, Voskas D, Dumont DJ, Ben-David Y, Lawler J, Henkin J, Huber J, Hicklin DJ, D'Amato RJ, Kerbel RS. Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; Implications for cellular surrogate marker analysis of antiangiogenesis. Cancer Cell. 2005 Jan; 7(1):101-11. PMID: 15652753.
    Citations: 106     Fields:    Translation:HumansAnimalsCells
  54. Efstathiou JA, Sampson DA, Levine Z, Rohan RM, Zurakowski D, Folkman J, D'Amato RJ, Rupnick MA. Nonsteroidal antiinflammatory drugs differentially suppress endometriosis in a murine model. Fertil Steril. 2005 Jan; 83(1):171-81. PMID: 15652904.
    Citations: 20     Fields:    Translation:HumansAnimals
  55. Yen L, Svendsen J, Lee JS, Gray JT, Magnier M, Baba T, D'Amato RJ, Mulligan RC. Exogenous control of mammalian gene expression through modulation of RNA self-cleavage. Nature. 2004 Sep 23; 431(7007):471-6. PMID: 15386015.
    Citations: 73     Fields:    Translation:HumansAnimalsCells
  56. Rogers MS, Rohan RM, Birsner AE, D'Amato RJ. Genetic loci that control the angiogenic response to basic fibroblast growth factor. FASEB J. 2004 Jul; 18(10):1050-9. PMID: 15226265.
    Citations: 16     Fields:    Translation:Animals
  57. Rogers MS, Rohan RM, Birsner AE, D'Amato RJ. Genetic loci that control vascular endothelial growth factor-induced angiogenesis. FASEB J. 2003 Nov; 17(14):2112-4. PMID: 12958152.
    Citations: 20     Fields:    Translation:Animals
  58. Kisker O, Onizuka S, Becker CM, Fannon M, Flynn E, D'Amato R, Zetter B, Folkman J, Ray R, Swamy N, Pirie-Shepherd S. Vitamin D binding protein-macrophage activating factor (DBP-maf) inhibits angiogenesis and tumor growth in mice. Neoplasia. 2003 Jan-Feb; 5(1):32-40. PMID: 12659668.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  59. Udagawa T, Fernandez A, Achilles EG, Folkman J, D'Amato RJ. Persistence of microscopic human cancers in mice: alterations in the angiogenic balance accompanies loss of tumor dormancy. FASEB J. 2002 Sep; 16(11):1361-70. PMID: 12205027.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  60. Lentzsch S, Rogers MS, LeBlanc R, Birsner AE, Shah JH, Treston AM, Anderson KC, D'Amato RJ. S-3-Amino-phthalimido-glutarimide inhibits angiogenesis and growth of B-cell neoplasias in mice. Cancer Res. 2002 Apr 15; 62(8):2300-5. PMID: 11956087.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  61. Hazzard TM, Rohan RM, Molskness TA, Fanton JW, D'Amato RJ, Stouffer RL. Injection of antiangiogenic agents into the macaque preovulatory follicle: disruption of corpus luteum development and function. Endocrine. 2002 Apr; 17(3):199-206. PMID: 12108520.
    Citations: 14     Fields:    Translation:Animals
  62. D'Amato RJ, Lentzsch S, Anderson KC, Rogers MS. Mechanism of action of thalidomide and 3-aminothalidomide in multiple myeloma. Semin Oncol. 2001 Dec; 28(6):597-601. PMID: 11740816.
    Citations: 9     Fields:    Translation:Humans
  63. Kisker O, Becker CM, Prox D, Fannon M, D'Amato R, Flynn E, Fogler WE, Sim BK, Allred EN, Pirie-Shepherd SR, Folkman J. Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model. Cancer Res. 2001 Oct 15; 61(20):7669-74. PMID: 11606410.
    Citations: 59     Fields:    Translation:HumansAnimals
  64. Stechschulte SU, Joussen AM, von Recum HA, Poulaki V, Moromizato Y, Yuan J, D'Amato RJ, Kuo C, Adamis AP. Rapid ocular angiogenic control via naked DNA delivery to cornea. Invest Ophthalmol Vis Sci. 2001 Aug; 42(9):1975-9. PMID: 11481260.
    Citations: 27     Fields:    Translation:Animals
  65. Gupta AR, Dejneka NS, D'Amato RJ, Yang Z, Syed N, Maguire AM, Bennett J. Strain-dependent anterior segment neovascularization following intravitreal gene transfer of basic fibroblast growth factor (bFGF). J Gene Med. 2001 May-Jun; 3(3):252-9. PMID: 11437330.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  66. Kuo CJ, Farnebo F, Yu EY, Christofferson R, Swearingen RA, Carter R, von Recum HA, Yuan J, Kamihara J, Flynn E, D'Amato R, Folkman J, Mulligan RC. Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer. Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4605-10. PMID: 11274374; PMCID: PMC31881.
    Citations: 79     Fields:    Translation:HumansAnimalsCells
  67. Schwesinger C, Yee C, Rohan RM, Joussen AM, Fernandez A, Meyer TN, Poulaki V, Ma JJ, Redmond TM, Liu S, Adamis AP, D'Amato RJ. Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epithelium. Am J Pathol. 2001 Mar; 158(3):1161-72. PMID: 11238064; PMCID: PMC1850362.
    Citations: 65     Fields:    Translation:AnimalsCells
  68. Fernandez A, Udagawa T, Schwesinger C, Beecken W, Achilles-Gerte E, McDonnell T, D'Amato R. Angiogenic potential of prostate carcinoma cells overexpressing bcl-2. J Natl Cancer Inst. 2001 Feb 07; 93(3):208-13. PMID: 11158189.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  69. Udagawa T, Yuan J, Panigrahy D, Chang YH, Shah J, D'Amato RJ. Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. J Pharmacol Exp Ther. 2000 Aug; 294(2):421-7. PMID: 10900214.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  70. Rohan RM, Fernandez A, Udagawa T, Yuan J, D'Amato RJ. Genetic heterogeneity of angiogenesis in mice. FASEB J. 2000 May; 14(7):871-6. PMID: 10783140.
    Citations: 67     Fields:    Translation:Animals
  71. Verheul HM, Panigrahy D, Flynn E, Pinedo HM, D'Amato RJ. Treatment of the Kasabach-Merritt syndrome with pegylated recombinant human megakaryocyte growth and development factor in mice: elevated platelet counts, prolonged survival, and tumor growth inhibition. Pediatr Res. 1999 Nov; 46(5):562-5. PMID: 10541319.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  72. Arbiser JL, Panigrathy D, Klauber N, Rupnick M, Flynn E, Udagawa T, D'Amato RJ. The antiangiogenic agents TNP-470 and 2-methoxyestradiol inhibit the growth of angiosarcoma in mice. J Am Acad Dermatol. 1999 Jun; 40(6 Pt 1):925-9. PMID: 10365923.
    Citations: 9     Fields:    Translation:Animals
  73. Verheul HM, Panigrahy D, Yuan J, D'Amato RJ. Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits. Br J Cancer. 1999 Jan; 79(1):114-8. PMID: 10408702; PMCID: PMC2362163.
    Citations: 19     Fields:    Translation:Animals
  74. Pinedo HM, Verheul HM, D'Amato RJ, Folkman J. Involvement of platelets in tumour angiogenesis? Lancet. 1998 Nov 28; 352(9142):1775-7. PMID: 9848370.
    Citations: 91     Fields:    Translation:HumansAnimalsCells
  75. Punglia RS, Lu M, Hsu J, Kuroki M, Tolentino MJ, Keough K, Levy AP, Levy NS, Goldberg MA, D'Amato RJ, Adamis AP. Regulation of vascular endothelial growth factor expression by insulin-like growth factor I. Diabetes. 1997 Oct; 46(10):1619-26. PMID: 9313759.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  76. Kenyon BM, Browne F, D'Amato RJ. Effects of thalidomide and related metabolites in a mouse corneal model of neovascularization. Exp Eye Res. 1997 Jun; 64(6):971-8. PMID: 9301478.
    Citations: 82     Fields:    Translation:Animals
  77. Klauber N, Rohan RM, Flynn E, D'Amato RJ. Critical components of the female reproductive pathway are suppressed by the angiogenesis inhibitor AGM-1470. Nat Med. 1997 Apr; 3(4):443-6. PMID: 9095179.
    Citations: 40     Fields:    Translation:Animals
  78. Klauber N, Parangi S, Flynn E, Hamel E, D'Amato RJ. Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol. Cancer Res. 1997 Jan 01; 57(1):81-6. PMID: 8988045.
    Citations: 96     Fields:    Translation:HumansAnimals
  79. Klauber N, Browne F, Anand-Apte B, D'Amato RJ. New activity of spironolactone. Inhibition of angiogenesis in vitro and in vivo. Circulation. 1996 Nov 15; 94(10):2566-71. PMID: 8921802.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  80. Loughman MS, Chatzistefanou K, Gonzalez EM, Flynn E, Adamis AP, Shing Y, D'Amato RJ, Folkman J. Experimental corneal neovascularisation using sucralfate and basic fibroblast growth factor. Aust N Z J Ophthalmol. 1996 Aug; 24(3):289-95. PMID: 8913136.
    Citations: 6     Fields:    Translation:Animals
  81. Kenyon BM, Voest EE, Chen CC, Flynn E, Folkman J, D'Amato RJ. A model of angiogenesis in the mouse cornea. Invest Ophthalmol Vis Sci. 1996 Jul; 37(8):1625-32. PMID: 8675406.
    Citations: 126     Fields:    Translation:Animals
  82. Hamel E, Lin CM, Flynn E, D'Amato RJ. Interactions of 2-methoxyestradiol, an endogenous mammalian metabolite, with unpolymerized tubulin and with tubulin polymers. Biochemistry. 1996 Jan 30; 35(4):1304-10. PMID: 8573587.
    Citations: 15     Fields:    Translation:Cells
  83. D'Amato RJ, Adamis AP. Angiogenesis inhibition in age-related macular degeneration. Ophthalmology. 1995 Sep; 102(9):1261-2. PMID: 9097761.
    Citations: 10     Fields:    Translation:HumansAnimals
  84. Adamis AP, D'Amato RJ. Shedding light on diabetic retinopathy. Ophthalmology. 1995 Aug; 102(8):1127-8. PMID: 9097736.
    Citations: 2     Fields:    Translation:HumansAnimals
  85. Voest EE, Kenyon BM, O'Reilly MS, Truitt G, D'Amato RJ, Folkman J. Inhibition of angiogenesis in vivo by interleukin 12. J Natl Cancer Inst. 1995 Apr 19; 87(8):581-6. PMID: 7538593.
    Citations: 148     Fields:    Translation:AnimalsCells
  86. D'Amato RJ, Lin CM, Flynn E, Folkman J, Hamel E. 2-Methoxyestradiol, an endogenous mammalian metabolite, inhibits tubulin polymerization by interacting at the colchicine site. Proc Natl Acad Sci U S A. 1994 Apr 26; 91(9):3964-8. PMID: 8171020; PMCID: PMC43703.
    Citations: 67     Fields:    Translation:AnimalsCells
  87. D'Amato RJ, Loughnan MS, Flynn E, Folkman J. Thalidomide is an inhibitor of angiogenesis. Proc Natl Acad Sci U S A. 1994 Apr 26; 91(9):4082-5. PMID: 7513432; PMCID: PMC43727.
    Citations: 485     Fields:    Translation:Animals
  88. Smith LE, Wesolowski E, McLellan A, Kostyk SK, D'Amato R, Sullivan R, D'Amore PA. Oxygen-induced retinopathy in the mouse. Invest Ophthalmol Vis Sci. 1994 Jan; 35(1):101-11. PMID: 7507904.
    Citations: 708     Fields:    Translation:HumansAnimals
  89. D'Amato R, Wesolowski E, Smith LE. Microscopic visualization of the retina by angiography with high-molecular-weight fluorescein-labeled dextrans in the mouse. Microvasc Res. 1993 Sep; 46(2):135-42. PMID: 7504160.
    Citations: 34     Fields:    Translation:Animals
  90. D'Amato RJ, Miller NR, Fine SL, Enger C, Quinlan P, Elman MJ. The effect of age and initial visual acuity on the systemic and visual prognosis of central retinal vein occlusion. Aust N Z J Ophthalmol. 1991 May; 19(2):118-22. PMID: 1930994.
    Citations: 2     Fields:    Translation:Humans
  91. D'Amato RJ, Largent BL, Snowman AM, Snyder SH. Selective labeling of serotonin uptake sites in rat brain by [3H]citalopram contrasted to labeling of multiple sites by [3H]imipramine. J Pharmacol Exp Ther. 1987 Jul; 242(1):364-71. PMID: 3475452.
    Citations: 45     Fields:    Translation:AnimalsCells
  92. D'Amato RJ, Alexander GM, Schwartzman RJ, Kitt CA, Price DL, Snyder SH. Evidence for neuromelanin involvement in MPTP-induced neurotoxicity. Nature. 1987 May 28-Jun 3; 327(6120):324-6. PMID: 2884568.
    Citations: 13     Fields:    Translation:AnimalsCells
  93. Snyder SH, D'Amato RJ. Predicting Parkinson's disease. Nature. 1985 Sep 19-25; 317(6034):198-9. PMID: 3876509.
    Citations: 13     Fields:    Translation:HumansAnimalsCellsPHPublic Health
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.