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profileSandra McAllister, PH.D.

TitleAssistant Professor of Medicine
InstitutionBrigham and Women's Hospital
DepartmentMedicine
AddressChildren's Hospital
Karp Building - 5
1 Blackfan Circle
Boston MA 02115
Phone617/355-9060
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Collapse Research 
Collapse research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R21CA182614     (MCALLISTER, SANDRA)Sep 1, 2014 - Aug 31, 2016
NIH/NCI
Understanding how the aging hematopoietic system affects cancer progression
Role: Principal Investigator

R01CA166284     (MCALLISTER, SANDRA S)Sep 18, 2012 - Dec 31, 2018
NIH/NCI
Understanding How Breast Cancers Activate and Respond to the Systemic Environment
Role: Principal Investigator

Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Goel S, DeCristo MJ, Watt AC, BrinJones H, Sceneay J, Li BB, Khan N, Ubellacker JM, Xie S, Metzger-Filho O, Hoog J, Ellis MJ, Ma CX, Ramm S, Krop IE, Winer EP, Roberts TM, Kim HJ, McAllister SS, Zhao JJ. CDK4/6 inhibition triggers anti-tumour immunity. Nature. 2017 Aug 24; 548(7668):471-475. PMID: 28813415.
    View in: PubMed
  2. Sceneay J, McAllister SS. The skinny on obesity and cancer. Nat Cell Biol. 2017 Jul 28; 19(8):887-888. PMID: 28752848.
    View in: PubMed
  3. Ubellacker JM, Haider MT, DeCristo MJ, Allocca G, Brown NJ, Silver DP, Holen I, McAllister SS. Zoledronic acid alters hematopoiesis and generates breast tumor-suppressive bone marrow cells. Breast Cancer Res. 2017 Mar 06; 19(1):23. PMID: 28264701.
    View in: PubMed
  4. Olsen SN, Wronski A, Castaño Z, Dake B, Malone C, De Raedt T, Enos M, DeRose YS, Zhou W, Guerra S, Loda M, Welm A, Partridge AH, McAllister SS, Kuperwasser C, Cichowski K. Loss of RasGAP Tumor Suppressors Underlies the Aggressive Nature of Luminal B Breast Cancers. Cancer Discov. 2017 Feb; 7(2):202-217. PMID: 27974415.
    View in: PubMed
  5. Henry WS, Laszewski T, Tsang T, Beca F, Beck AH, McAllister SS, Toker A. Aspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling. Cancer Res. 2017 Feb 01; 77(3):790-801. PMID: 27940576.
    View in: PubMed
  6. Ubellacker JM, McAllister SS. The unresolved role of systemic factors in bone metastasis. J Bone Oncol. 2016 Sep; 5(3):96-99. PMID: 27761365.
    View in: PubMed
  7. Marsh T, Wong I, Sceneay J, Barakat A, Qin Y, Sjödin A, Alspach E, Nilsson B, Stewart SA, McAllister SS. Hematopoietic Age at Onset of Triple-Negative Breast Cancer Dictates Disease Aggressiveness and Progression. Cancer Res. 2016 May 15; 76(10):2932-43. PMID: 27197230.
    View in: PubMed
  8. McAllister SS, Weinberg RA. The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis. Nat Cell Biol. 2014 Aug; 16(8):717-27. PMID: 25082194.
    View in: PubMed
  9. Qin Y, McAllister SS. SPSB1 may have MET its match during breast cancer recurrence. Cancer Discov. 2014 Jul; 4(7):760-1. PMID: 25002612; PMCID: PMC4090600.
  10. Alspach E, Flanagan KC, Luo X, Ruhland MK, Huang H, Pazolli E, Donlin MJ, Marsh T, Piwnica-Worms D, Monahan J, Novack DV, McAllister SS, Stewart SA. p38MAPK plays a crucial role in stromal-mediated tumorigenesis. Cancer Discov. 2014 Jun; 4(6):716-29. PMID: 24670723; PMCID: PMC4049323.
  11. Shaked Y, McAllister S, Fainaru O, Almog N. Tumor dormancy and the angiogenic switch: possible implications of bone marrow- derived cells. Curr Pharm Des. 2014; 20(30):4920-33. PMID: 24283950.
    View in: PubMed
  12. Redig AJ, McAllister SS. Breast cancer as a systemic disease: a view of metastasis. J Intern Med. 2013 Aug; 274(2):113-26. PMID: 23844915; PMCID: PMC3711134.
  13. Castaño Z, Marsh T, Tadipatri R, Kuznetsov HS, Al-Shahrour F, Paktinat M, Greene-Colozzi A, Nilsson B, Richardson AL, McAllister SS. Stromal EGF and igf-I together modulate plasticity of disseminated triple-negative breast tumors. Cancer Discov. 2013 Aug; 3(8):922-35. PMID: 23689072; PMCID: PMC3740018.
  14. Marsh T, Pietras K, McAllister SS. Fibroblasts as architects of cancer pathogenesis. Biochim Biophys Acta. 2013 Jul; 1832(7):1070-8. PMID: 23123598; PMCID: PMC3775582.
  15. Kuznetsov HS, Marsh T, Markens BA, Castaño Z, Greene-Colozzi A, Hay SA, Brown VE, Richardson AL, Signoretti S, Battinelli EM, McAllister SS. Identification of luminal breast cancers that establish a tumor-supportive macroenvironment defined by proangiogenic platelets and bone marrow-derived cells. Cancer Discov. 2012 Dec; 2(12):1150-65. PMID: 22896036; PMCID: PMC3517696.
  16. McAllister SS. Got a light? Illuminating lung cancer. Sci Transl Med. 2012 Jul 11; 4(142):142fs22. PMID: 22786678.
    View in: PubMed
  17. Castaño Z, Fillmore CM, Kim CF, McAllister SS. The bed and the bugs: interactions between the tumor microenvironment and cancer stem cells. Semin Cancer Biol. 2012 Oct; 22(5-6):462-70. PMID: 22548722; PMCID: PMC3445659.
  18. Elkabets M, Gifford AM, Scheel C, Nilsson B, Reinhardt F, Bray MA, Carpenter AE, Jirström K, Magnusson K, Ebert BL, Pontén F, Weinberg RA, McAllister SS. Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice. J Clin Invest. 2011 Feb; 121(2):784-99. PMID: 21266779; PMCID: PMC3026724.
  19. Castaño Z, Tracy K, McAllister SS. The tumor macroenvironment and systemic regulation of breast cancer progression. Int J Dev Biol. 2011; 55(7-9):889-97. PMID: 22161844.
    View in: PubMed
  20. McAllister SS, Weinberg RA. Tumor-host interactions: a far-reaching relationship. J Clin Oncol. 2010 Sep 10; 28(26):4022-8. PMID: 20644094.
    View in: PubMed
  21. Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, Liu A, Miu K, Watnick RS, Reinhardt F, McAllister SS, Jacks T, Weinberg RA. Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 2008 Jul 11; 134(1):62-73. PMID: 18614011; PMCID: PMC3222460.
  22. McAllister SS, Gifford AM, Greiner AL, Kelleher SP, Saelzler MP, Ince TA, Reinhardt F, Harris LN, Hylander BL, Repasky EA, Weinberg RA. Systemic endocrine instigation of indolent tumor growth requires osteopontin. Cell. 2008 Jun 13; 133(6):994-1005. PMID: 18555776; PMCID: PMC4121664.
  23. Becker-Hapak M, McAllister SS, Dowdy SF. TAT-mediated protein transduction into mammalian cells. Methods. 2001 Jul; 24(3):247-56. PMID: 11403574.
    View in: PubMed
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