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Herbert Ben Hechtman, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P50GM052585 (MOORE, FRANCIS D) Apr 1, 1995 - Sep 29, 2003
    NIH/NIGMS
    Augmented Injury due to Autologous Inflammatory Attack
    Role: Co-Principal Investigator
  2. R01GM035141 (HECHTMAN, HERBERT B.) Jul 1, 1985 - Mar 31, 2000
    NIH/NIGMS
    LOCAL AND SYSTEMIC CONSEQUENCES OF ISCHEMIA
    Role: Principal Investigator
  3. R01GM024891 (HECHTMAN, HERBERT B.) Jul 1, 1977 - Mar 31, 2001
    NIH/NIGMS
    CARDIOPULMONARY FAILURE FOLLOWING SHOCK AND TRAUMA
    Role: Principal Investigator
  4. T32GM007560 (MOORE, FRANCIS D) Jul 1, 1977 - Jun 30, 2000
    NIH/NIGMS
    TRAUMA AND BURN RESEARCH
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Hechtman HB. Clinical activity and mode of action of poly-N-acetyl glucosamine fiber materials: hemostasis and wound healing. Foreword. J Trauma. 2011 Aug; 71(2 Suppl 1):S161. PMID: 21814111.
    Citations:    Fields:    Translation:HumansAnimals
  2. Scherer SS, Pietramaggiori G, Matthews J, Perry S, Assmann A, Carothers A, Demcheva M, Muise-Helmericks RC, Seth A, Vournakis JN, Valeri RC, Fischer TH, Hechtman HB, Orgill DP. Poly-N-acetyl glucosamine nanofibers: a new bioactive material to enhance diabetic wound healing by cell migration and angiogenesis. Ann Surg. 2009 Aug; 250(2):322-30. PMID: 19638916.
    Citations: 13     Fields:    Translation:AnimalsCells
  3. Pietramaggiori G, Yang HJ, Scherer SS, Kaipainen A, Chan RK, Alperovich M, Newalder J, Demcheva M, Vournakis JN, Valeri CR, Hechtman HB, Orgill DP. Effects of poly-N-acetyl glucosamine (pGlcNAc) patch on wound healing in db/db mouse. J Trauma. 2008 Mar; 64(3):803-8. PMID: 18332827.
    Citations: 9     Fields:    Translation:Animals
  4. Chan RK, Liu PH, Pietramaggiori G, Ibrahim SI, Hechtman HB, Orgill DP. Effect of recombinant platelet-derived growth factor (Regranex) on wound closure in genetically diabetic mice. J Burn Care Res. 2006 Mar-Apr; 27(2):202-5. PMID: 16566566.
    Citations: 19     Fields:    Translation:Animals
  5. Chan RK, Liu P, Lew DH, Ibrahim SI, Srey R, Valeri CR, Hechtman HB, Orgill DP. Expired liquid preserved platelet releasates retain proliferative activity. J Surg Res. 2005 Jun 01; 126(1):55-8. PMID: 15916975.
    Citations: 1     Fields:    Translation:HumansCells
  6. Chan RK, Ding G, Verna N, Ibrahim S, Oakes S, Austen WG, Hechtman HB, Moore FD. IgM binding to injured tissue precedes complement activation during skeletal muscle ischemia-reperfusion. J Surg Res. 2004 Nov; 122(1):29-35. PMID: 15522311.
    Citations: 7     Fields:    Translation:Animals
  7. Chan RK, Austen WG, Ibrahim S, Ding GY, Verna N, Hechtman HB, Moore FD. Reperfusion injury to skeletal muscle affects primarily type II muscle fibers. J Surg Res. 2004 Nov; 122(1):54-60. PMID: 15522315.
    Citations: 12     Fields:    Translation:AnimalsCells
  8. Austen WG, Zhang M, Chan R, Friend D, Hechtman HB, Carroll MC, Moore FD. Murine hindlimb reperfusion injury can be initiated by a self-reactive monoclonal IgM. Surgery. 2004 Aug; 136(2):401-6. PMID: 15300207.
    Citations: 24     Fields:    Translation:Animals
  9. Favuzza J, Hechtman HB. Hemostasis in the absence of clotting factors. J Trauma. 2004 Jul; 57(1 Suppl):S42-4. PMID: 15280751.
    Citations: 1     Fields:    Translation:Animals
  10. Zhang M, Austen WG, Chiu I, Alicot EM, Hung R, Ma M, Verna N, Xu M, Hechtman HB, Moore FD, Carroll MC. Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury. Proc Natl Acad Sci U S A. 2004 Mar 16; 101(11):3886-91. PMID: 14999103.
    Citations: 88     Fields:    Translation:AnimalsCells
  11. Chan RK, Ibrahim SI, Verna N, Carroll M, Moore FD, Hechtman HB. Ischaemia-reperfusion is an event triggered by immune complexes and complement. Br J Surg. 2003 Dec; 90(12):1470-8. PMID: 14648724.
    Citations: 20     Fields:    Translation:HumansCells
  12. Austen WG, Kobzik L, Carroll MC, Hechtman HB, Moore FD. The role of complement and natural antibody in intestinal ischemia-reperfusion injury. Int J Immunopathol Pharmacol. 2003 Jan-Apr; 16(1):1-8. PMID: 12578725.
    Citations: 9     Fields:    Translation:HumansAnimals
  13. Reid RR, Woodcock S, Shimabukuro-Vornhagen A, Austen WG, Kobzik L, Zhang M, Hechtman HB, Moore FD, Carroll MC. Functional activity of natural antibody is altered in Cr2-deficient mice. J Immunol. 2002 Nov 15; 169(10):5433-40. PMID: 12421918.
    Citations: 28     Fields:    Translation:AnimalsCells
  14. Lieberthal W, Fuhro R, Alam H, Rhee P, Szebeni J, Hechtman HB, Favuzza J, Veech RL, Valeri CR. Comparison of the effects of a 50% exchange-transfusion with albumin, hetastarch, and modified hemoglobin solutions. Shock. 2002 Jan; 17(1):61-9. PMID: 11795671.
    Citations: 3     Fields:    Translation:HumansAnimals
  15. Kyriakides C, Wang Y, Austen WG, Favuzza J, Kobzik L, Moore FD, Hechtman HB. Sialyl Lewis(x) hybridized complement receptor type 1 moderates acid aspiration injury. Am J Physiol Lung Cell Mol Physiol. 2001 Dec; 281(6):L1494-9. PMID: 11704546.
    Citations: 1     Fields:    Translation:AnimalsCells
  16. Valeri CR, Dennis RC, Ragno G, Pivacek LE, Hechtman HB, Khuri SF. Survival, function, and hemolysis of shed red blood cells processed as nonwashed blood and washed red blood cells. Ann Thorac Surg. 2001 Nov; 72(5):1598-602. PMID: 11722051.
    Citations: 1     Fields:    Translation:AnimalsCells
  17. Valeri CR, Ragno G, Pivacek LE, Dennis RC, Hechtman HB, Khuri SF. Survival and function of baboon RBCs released from clotted blood and washed before autologous transfusion. Transfusion. 2001 Nov; 41(11):1384-9. PMID: 11724982.
    Citations:    Fields:    Translation:AnimalsCells
  18. Lim MJ, Chiang ET, Hechtman HB, Shepro D. Inflammation-induced subcellular redistribution of VE-cadherin, actin, and gamma-catenin in cultured human lung microvessel endothelial cells. Microvasc Res. 2001 Nov; 62(3):366-82. PMID: 11678639.
    Citations: 8     Fields:    Translation:HumansCells
  19. Mukundan C, Gurish MF, Austen KF, Hechtman HB, Friend DS. Mast cell mediation of muscle and pulmonary injury following hindlimb ischemia-reperfusion. J Histochem Cytochem. 2001 Aug; 49(8):1055-6. PMID: 11457933.
    Citations: 7     Fields:    Translation:AnimalsCells
  20. Kyriakides C, Austen WG, Wang Y, Favuzza J, Kobzik L, Moore FD, Hechtman HB. Mast cells mediate complement activation after acid aspiration. Shock. 2001 Jul; 16(1):21-4. PMID: 11442310.
    Citations: 1     Fields:    Translation:AnimalsCells
  21. Kyriakides C, Wang Y, Austen WG, Favuzza J, Kobzik L, Moore FD, Hechtman HB. Moderation of skeletal muscle reperfusion injury by a sLe(x)-glycosylated complement inhibitory protein. Am J Physiol Cell Physiol. 2001 Jul; 281(1):C224-30. PMID: 11401845.
    Citations: 4     Fields:    Translation:AnimalsCells
  22. Mukundan C, Gurish MF, Austen KF, Hechtman HB, Friend DS. The presence of v-abl-transformed V3 mast cells in the lungs augments pulmonary vascular permeability to acid aspiration. J Histochem Cytochem. 2001 Jun; 49(6):793-4. PMID: 11373327.
    Citations:    Fields:    Translation:AnimalsCells
  23. Kyriakides C, Favuzza J, Wang Y, Austen WG, Moore FD, Hechtman HB. Recombinant soluble P-selectin glycoprotein ligand 1 moderates local and remote injuries following experimental lower-torso ischaemia. Br J Surg. 2001 Jun; 88(6):825-30. PMID: 11412252.
    Citations: 3     Fields:    Translation:Animals
  24. Kyriakides C, Jasleen J, Wang Y, Moore FD, Ashley SW, Hechtman HB. Neutrophils, not complement, mediate the mortality of experimental hemorrhagic pancreatitis. Pancreas. 2001 Jan; 22(1):40-6. PMID: 11138969.
    Citations: 7     Fields:    Translation:AnimalsCells
  25. Woodcock SA, Kyriakides C, Wang Y, Austen WG, Moore FD, Valeri R, Hartwell D, Hechtman HB. Soluble P-selectin moderates complement dependent injury. Shock. 2000 Dec; 14(6):610-5. PMID: 11131910.
    Citations: 3     Fields:    Translation:AnimalsCells
  26. Kyriakides C, Austen W, Wang Y, Favuzza J, Moore FD, Hechtman HB. Endothelial selectin blockade attenuates lung permeability of experimental acid aspiration. Surgery. 2000 Aug; 128(2):327-31. PMID: 10923012.
    Citations: 8     Fields:    Translation:AnimalsCells
  27. Kyriakides C, Woodcock SA, Wang Y, Favuzza J, Austen WG, Kobzik L, Moore FD, Valeri RC, Shepro D, Hechtman HB. Soluble P-selectin moderates complement-dependent reperfusion injury of ischemic skeletal muscle. Am J Physiol Cell Physiol. 2000 Aug; 279(2):C520-8. PMID: 10913019.
    Citations: 3     Fields:    Translation:HumansAnimals
  28. Kyriakides C, Austen WG, Wang Y, Favuzza J, Moore FD, Hechtman HB. Neutrophil mediated remote organ injury after lower torso ischemia and reperfusion is selectin and complement dependent. J Trauma. 2000 Jan; 48(1):32-8. PMID: 10647562.
    Citations: 13     Fields:    Translation:AnimalsCells
  29. Reid RR, Woodcock S, Prodeus AP, Austen J, Kobzik L, Hechtman H, Moore FD, Carroll MC. The role of complement receptors CD21/CD35 in positive selection of B-1 cells. Curr Top Microbiol Immunol. 2000; 252:57-65. PMID: 11187085.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  30. Kyriakides C, Austen W, Wang Y, Favuzza J, Kobzik L, Moore FD, Hechtman HB. Skeletal muscle reperfusion injury is mediated by neutrophils and the complement membrane attack complex. Am J Physiol. 1999 12; 277(6):C1263-8. PMID: 10600778.
    Citations: 17     Fields:    Translation:AnimalsCells
  31. Kyriakides C, Austen W, Wang Y, Favuzza J, Kobzik L, Moore FD, Hechtman HB. Membrane attack complex of complement and neutrophils mediate the injury of acid aspiration. J Appl Physiol (1985). 1999 Dec; 87(6):2357-61. PMID: 10601189.
    Citations: 4     Fields:    Translation:AnimalsCells
  32. Shojaee N, Patton WF, Hechtman HB, Shepro D. Myosin translocation in retinal pericytes during free-radical induced apoptosis. J Cell Biochem. 1999 Oct 01; 75(1):118-29. PMID: 10462710.
    Citations: 10     Fields:    Translation:AnimalsCells
  33. Austen WG, Kyriakides C, Favuzza J, Wang Y, Kobzik L, Moore FD, Hechtman HB. Intestinal ischemia-reperfusion injury is mediated by the membrane attack complex. Surgery. 1999 Aug; 126(2):343-8. PMID: 10455904.
    Citations: 13     Fields:    Translation:AnimalsCells
  34. Barnard MR, MacGregor H, Mercier R, Ragno G, Pivacek LE, Hechtman HB, Michelson AD, Valeri CR. Platelet surface p-selectin, platelet-granulocyte heterotypic aggregates, and plasma-soluble p-selectin during plateletpheresis. Transfusion. 1999 Jul; 39(7):735-41. PMID: 10413281.
    Citations: 1     Fields:    Translation:HumansCells
  35. Williams JP, Pechet TT, Weiser MR, Reid R, Kobzik L, Moore FD, Carroll MC, Hechtman HB. Intestinal reperfusion injury is mediated by IgM and complement. J Appl Physiol (1985). 1999 Mar; 86(3):938-42. PMID: 10066708.
    Citations: 70     Fields:    Translation:Animals
  36. Peyton BD, Rohrer MJ, Furman MI, Barnard MR, Rodino LJ, Benoit SE, Hechtman HB, Valeri CR, Michelson AD. Patients with venous stasis ulceration have increased monocyte-platelet aggregation. J Vasc Surg. 1998 Jun; 27(6):1109-15; discussion 1115-6. PMID: 9652473.
    Citations: 1     Fields:    Translation:HumansCells
  37. Hastie LE, Patton WF, Hechtman HB, Shepro D. Metabolites of the phospholipase D pathway regulate H2O2-induced filamin redistribution in endothelial cells. J Cell Biochem. 1998 Mar 15; 68(4):511-24. PMID: 9493913.
    Citations: 5     Fields:    Translation:HumansCells
  38. Shojaee N, Patton WF, Chung-Welch N, Su Q, Hechtman HB, Shepro D. Expression and subcellular distribution of filamin isotypes in endothelial cells and pericytes. Electrophoresis. 1998 Feb; 19(2):323-32. PMID: 9548299.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  39. Furman MI, Benoit SE, Barnard MR, Valeri CR, Borbone ML, Becker RC, Hechtman HB, Michelson AD. Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. J Am Coll Cardiol. 1998 Feb; 31(2):352-8. PMID: 9462579.
    Citations: 80     Fields:    Translation:HumansCells
  40. Wang Q, Patton WF, Hechtman HB, Shepro D. Activation of endothelial cell kinin receptors leads to intracellular calcium increases and filamin translocation: regulation by protein kinase C. Cell Signal. 1997 Dec; 9(8):595-602. PMID: 9429763.
    Citations: 2     Fields:    Translation:AnimalsCells
  41. Williams JP, Weiser MR, Pechet TT, Kobzik L, Moore FD, Hechtman HB. alpha 1-Acid glycoprotein reduces local and remote injuries after intestinal ischemia in the rat. Am J Physiol. 1997 11; 273(5):G1031-5. PMID: 9374699.
    Citations: 12     Fields:    Translation:HumansAnimals
  42. Weiser MR, Pechet TT, Williams JP, Ma M, Frenette PS, Moore FD, Kobzik L, Hines RO, Wagner DD, Carroll MC, Hechtman HB. Experimental murine acid aspiration injury is mediated by neutrophils and the alternative complement pathway. J Appl Physiol (1985). 1997 Oct; 83(4):1090-5. PMID: 9338415.
    Citations: 6     Fields:    Translation:AnimalsCells
  43. Hastie LE, Patton WF, Hechtman HB, Shepro D. H2O2-induced filamin redistribution in endothelial cells is modulated by the cyclic AMP-dependent protein kinase pathway. J Cell Physiol. 1997 Sep; 172(3):373-81. PMID: 9284957.
    Citations: 15     Fields:    Translation:HumansCells
  44. Wang Q, Patton WF, Hechtman HB, Shepro D. A novel anti-inflammatory peptide inhibits endothelial cell cytoskeletal rearrangement, nitric oxide synthase translocation, and paracellular permeability increases. J Cell Physiol. 1997 Aug; 172(2):171-82. PMID: 9258338.
    Citations: 9     Fields:    Translation:AnimalsCells
  45. Morel NM, Xu CB, Hechtman HB, Shepro D. Microvessel mural cell secretions modulate endothelial monolayer permeability. Microvasc Res. 1997 Mar; 53(2):197-200. PMID: 9143555.
    Citations: 1     Fields:    Translation:AnimalsCells
  46. Hastie LE, Patton WF, Hechtman HB, Shepro D. Filamin redistribution in an endothelial cell reoxygenation injury model. Free Radic Biol Med. 1997; 22(6):955-66. PMID: 9034234.
    Citations: 7     Fields:    Translation:HumansCells
  47. Patton WF, Wang Q, Chiang ET, Hechtman HB, Shepro D. Antamanide Prevents Bradykinin-lnduced Filamin Translocation by Inhibiting Extracellular Calcium Influx. Drug Deliv. 1997; 4(4):247-54. PMID: 26582443.
    Citations:    Fields:    
  48. Michelson AD, Barnard MR, Hechtman HB, MacGregor H, Connolly RJ, Loscalzo J, Valeri CR. In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11877-82. PMID: 8876231.
    Citations: 65     Fields:    Translation:AnimalsCells
  49. Wang Q, Patton WF, Chiang ET, Hechtman HB, Shepro D. Filamin translocation is an early endothelial cell inflammatory response to bradykinin: regulation by calcium, protein kinases, and protein phosphatases. J Cell Biochem. 1996 Sep 01; 62(3):383-96. PMID: 8872609.
    Citations: 9     Fields:    Translation:AnimalsCells
  50. Hechtman HB, Barlow C. Moderation of anal sphincter tone with nitric oxide agonists and antagonists. Arch Surg. 1996 Jul; 131(7):775-84. PMID: 8678781.
    Citations: 1     Fields:    Translation:Animals
  51. Gibbs SA, Weiser MR, Kobzik L, Valeri CR, Shepro D, Hechtman HB. P-selectin mediates intestinal ischemic injury by enhancing complement deposition. Surgery. 1996 Jun; 119(6):652-6. PMID: 8650605.
    Citations: 2     Fields:    Translation:AnimalsCells
  52. Weiser MR, Gibbs SA, Valeri CR, Shepro D, Hechtman HB. Anti-selectin therapy modifies skeletal muscle ischemia and reperfusion injury. Shock. 1996 Jun; 5(6):402-7. PMID: 8799951.
    Citations: 2     Fields:    Translation:Animals
  53. Weiser MR, Williams JP, Moore FD, Kobzik L, Ma M, Hechtman HB, Carroll MC. Reperfusion injury of ischemic skeletal muscle is mediated by natural antibody and complement. J Exp Med. 1996 May 01; 183(5):2343-8. PMID: 8642343.
    Citations: 96     Fields:    Translation:Animals
  54. Weiser MR, Gibbs SA, Moore FD, Hechtman HB. Complement inhibition by soluble complement receptor type 1 fails to moderate cerulein-induced pancreatitis in the rat. Int J Pancreatol. 1996 Apr; 19(2):129-34. PMID: 8723555.
    Citations: 2     Fields:    Translation:Animals
  55. Goldman G, Welbourn R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Neutrophil adhesion receptor CD18 mediates remote but not localized acid aspiration injury. Surgery. 1995 Jan; 117(1):83-9. PMID: 7809841.
    Citations: 3     Fields:    Translation:AnimalsCells
  56. Klausner JM, Abu-Abid S, Alexander JS, Hanshke-Mineau R, Goldman G, Morel N, Valeri CR, Shepro D, Hechtman HB. Thromboxane modulates endothelial permeability. Mediators Inflamm. 1994; 3(2):149-53. PMID: 18472934.
    Citations: 3     Fields:    
  57. Simpson R, Hechtman HB. Pulmonary injury following sepsis. Prog Clin Biol Res. 1994; 388:265-75. PMID: 7530367.
    Citations:    Fields:    Translation:HumansAnimalsCells
  58. Simpson R, Alon R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Neutrophil and nonneutrophil-mediated injury in intestinal ischemia-reperfusion. Ann Surg. 1993 Oct; 218(4):444-53; discussion 453-4. PMID: 8215636.
    Citations: 31     Fields:    Translation:AnimalsCells
  59. Simpson R, Alon R, Valeri CR, Shepro D, Hechtman HB. Integrin dependent neutrophil adhesion following gut ischemia and reperfusion. Behring Inst Mitt. 1993 Aug; (92):210-7. PMID: 7902703.
    Citations:    Fields:    Translation:HumansAnimalsCells
  60. Goldman G, Welbourn R, Klausner JM, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Leukocytes mediate acid aspiration-induced multiorgan edema. Surgery. 1993 Jul; 114(1):13-20. PMID: 8395089.
    Citations: 8     Fields:    Translation:AnimalsCells
  61. Wiles ME, Hechtman HB, Morel NM, Shepro D. Hypoxia reoxygenation-induced injury of cultured pulmonary microvessel endothelial cells. J Leukoc Biol. 1993 May; 53(5):490-7. PMID: 8388909.
    Citations: 5     Fields:    Translation:AnimalsCells
  62. Goldman G, Welbourn R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Lavage with leukotriene B4 induces lung generation of tumor necrosis factor-alpha that in turn mediates neutrophil diapedesis. Surgery. 1993 Mar; 113(3):297-303. PMID: 8382842.
    Citations: 7     Fields:    Translation:AnimalsCells
  63. Mineau-Hanschke R, Patton WF, Hechtman HB, Shepro D. Immunolocalization of cytokeratin 19 in bovine and human pulmonary microvascular endothelial cells in situ. Comp Biochem Physiol Comp Physiol. 1993 Feb; 104(2):313-9. PMID: 7680974.
    Citations: 1     Fields:    Translation:HumansAnimals
  64. Hill J, Lindsay T, Valeri CR, Shepro D, Hechtman HB. A CD18 antibody prevents lung injury but not hypotension after intestinal ischemia-reperfusion. J Appl Physiol (1985). 1993 Feb; 74(2):659-64. PMID: 8096207.
    Citations: 3     Fields:    Translation:AnimalsCells
  65. Lindsay TF, Hill J, Ortiz F, Rudolph A, Valeri CR, Hechtman HB, Moore FD. Blockade of complement activation prevents local and pulmonary albumin leak after lower torso ischemia-reperfusion. Ann Surg. 1992 Dec; 216(6):677-83. PMID: 1334645.
    Citations: 13     Fields:    Translation:Animals
  66. Hill J, Lindsay TF, Ortiz F, Yeh CG, Hechtman HB, Moore FD. Soluble complement receptor type 1 ameliorates the local and remote organ injury after intestinal ischemia-reperfusion in the rat. J Immunol. 1992 Sep 01; 149(5):1723-8. PMID: 1387151.
    Citations: 53     Fields:    Translation:AnimalsCells
  67. Goldman G, Welbourn R, Klausner JM, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Mast cells and leukotrienes mediate neutrophil sequestration and lung edema after remote ischemia in rodents. Surgery. 1992 Sep; 112(3):578-86. PMID: 1325674.
    Citations: 7     Fields:    Translation:AnimalsCells
  68. Goldman G, Welbourn R, Rothlein R, Wiles M, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Adherent neutrophils mediate permeability after atelectasis. Ann Surg. 1992 Sep; 216(3):372-8; discussion 378-80. PMID: 1417186.
    Citations: 1     Fields:    Translation:AnimalsCells
  69. Hill J, Lindsay T, Rusche J, Valeri CR, Shepro D, Hechtman HB. A Mac-1 antibody reduces liver and lung injury but not neutrophil sequestration after intestinal ischemia-reperfusion. Surgery. 1992 Aug; 112(2):166-72. PMID: 1353637.
    Citations: 13     Fields:    Translation:AnimalsCells
  70. Goldman G, Welbourn R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Reactive oxygen species and elastase mediate lung permeability after acid aspiration. J Appl Physiol (1985). 1992 Aug; 73(2):571-5. PMID: 1399982.
    Citations: 13     Fields:    Translation:AnimalsCells
  71. Welbourn R, Goldman G, Kobzik L, Paterson IS, Valeri CR, Shepro D, Hechtman HB. Role of neutrophil adherence receptors (CD 18) in lung permeability following lower torso ischemia. Circ Res. 1992 Jul; 71(1):82-6. PMID: 1351425.
    Citations: 8     Fields:    Translation:AnimalsCells
  72. Goldman G, Welbourn R, Klausner JM, Valeri CR, Shepro D, Hechtman HB. Oxygen free radicals are required for ischemia-induced leukotriene B4 synthesis and diapedesis. Surgery. 1992 Mar; 111(3):287-93. PMID: 1311874.
    Citations: 3     Fields:    Translation:AnimalsCells
  73. Goldman G, Welbourn R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Synergism between leukotriene B4 and thromboxane A2 in mediating acid-aspiration injury. Surgery. 1992 Jan; 111(1):55-61. PMID: 1309402.
    Citations: 6     Fields:    Translation:AnimalsCells
  74. Welbourn R, Goldman G, Kobzik L, Paterson I, Shepro D, Hechtman HB. Interleukin-2 induces early multisystem organ edema mediated by neutrophils. Ann Surg. 1991 Aug; 214(2):181-6. PMID: 1867524.
    Citations: 6     Fields:    Translation:AnimalsCells
  75. Patton WF, Alexander JS, Dodge AB, Patton RJ, Hechtman HB, Shepro D. Mercury-arc photolysis: a method for examining second messenger regulation of endothelial cell monolayer integrity. Anal Biochem. 1991 Jul; 196(1):31-8. PMID: 1653549.
    Citations: 1     Fields:    Translation:AnimalsCells
  76. Welbourn CR, Goldman G, Paterson IS, Valeri CR, Shepro D, Hechtman HB. Pathophysiology of ischaemia reperfusion injury: central role of the neutrophil. Br J Surg. 1991 Jun; 78(6):651-5. PMID: 2070226.
    Citations: 58     Fields:    Translation:HumansCells
  77. Wiles ME, Welbourn R, Goldman G, Hechtman HB, Shepro D. Thromboxane-induced neutrophil adhesion to pulmonary microvascular and aortic endothelium is regulated by CD18. Inflammation. 1991 Jun; 15(3):181-99. PMID: 1682250.
    Citations: 6     Fields:    Translation:AnimalsCells
  78. Welbourn R, Goldman G, O'Riordain M, Lindsay TF, Paterson IS, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Role for tumor necrosis factor as mediator of lung injury following lower torso ischemia. J Appl Physiol (1985). 1991 Jun; 70(6):2645-9. PMID: 1885460.
    Citations: 19     Fields:    Translation:AnimalsCells
  79. Welbourn CR, Goldman G, Paterson IS, Valeri CR, Shepro D, Hechtman HB. Neutrophil elastase and oxygen radicals: synergism in lung injury after hindlimb ischemia. Am J Physiol. 1991 Jun; 260(6 Pt 2):H1852-6. PMID: 2058722.
    Citations: 13     Fields:    Translation:AnimalsCells
  80. Goldman G, Welbourn R, Valeri CR, Shepro D, Hechtman HB. Thromboxane A2 induces leukotriene B4 synthesis that in turn mediates neutrophil diapedesis via CD 18 activation. Microvasc Res. 1991 May; 41(3):367-75. PMID: 1677155.
    Citations: 4     Fields:    Translation:AnimalsCells
  81. Goldman G, Welbourn R, Klausner JM, Valeri CR, Shepro D, Hechtman HB. Thromboxane mediates diapedesis after ischemia by activation of neutrophil adhesion receptors interacting with basally expressed intercellular adhesion molecule-1. Circ Res. 1991 Apr; 68(4):1013-9. PMID: 1672629.
    Citations: 5     Fields:    Translation:AnimalsCells
  82. Goldman G, Welbourn R, Alexander S, Klausner JM, Wiles M, Valeri CR, Shepro D, Hechtman HB. Modulation of pulmonary permeability in vivo with agents that affect the cytoskeleton. Surgery. 1991 Apr; 109(4):533-8. PMID: 1848951.
    Citations: 2     Fields:    Translation:AnimalsCells
  83. Goldman G, Welbourn R, Klausner JM, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Neutrophil accumulations due to pulmonary thromboxane synthesis mediate acid aspiration injury. J Appl Physiol (1985). 1991 Apr; 70(4):1511-7. PMID: 2055829.
    Citations: 7     Fields:    Translation:AnimalsCells
  84. Welbourn R, Goldman G, Kobzik L, Valeri CR, Hechtman HB, Shepro D. Attenuation of IL-2-induced multisystem organ edema by phalloidin and antamanide. J Appl Physiol (1985). 1991 Mar; 70(3):1364-8. PMID: 2033005.
    Citations: 3     Fields:    Translation:Animals
  85. Goldman G, Welbourn R, Klausner JM, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Intravascular chemoattractants inhibit diapedesis by selective receptor occupancy. Am J Physiol. 1991 Feb; 260(2 Pt 2):H465-72. PMID: 1847598.
    Citations: 1     Fields:    Translation:AnimalsCells
  86. Klausner JM, Paterson IS, Goldman G, Kobzik L, Lelcuk S, Skornick Y, Eberlein T, Valeri CR, Shepro D, Hechtman HB. Interleukin-2-induced lung injury is mediated by oxygen free radicals. Surgery. 1991 Feb; 109(2):169-75. PMID: 1899491.
    Citations: 1     Fields:    Translation:Animals
  87. Dodge AB, Patton WF, Yoon MU, Hechtman HB, Shepro D. Organ and species specific differences in cytoskeletal protein profiles of cultured microvascular endothelial cells. Comp Biochem Physiol B. 1991; 98(4):461-70. PMID: 1714365.
    Citations: 1     Fields:    Translation:AnimalsCells
  88. Dodge AB, Hechtman HB, Shepro D. Microvascular endothelial-derived autacoids regulate pericyte contractility. Cell Motil Cytoskeleton. 1991; 18(3):180-8. PMID: 2060030.
    Citations: 12     Fields:    Translation:AnimalsCells
  89. Klausner JM, Goldman G, Skornick Y, Valeri R, Inbar M, Shepro D, Hechtman HB. Interleukin-2-induced lung permeability is mediated by leukotriene B4. Cancer. 1990 Dec 01; 66(11):2357-64. PMID: 2173970.
    Citations: 3     Fields:    Translation:Animals
  90. Welbourn R, Goldman G, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Involvement of thromboxane and neutrophils in multiple-system organ edema with interleukin-2. Ann Surg. 1990 Dec; 212(6):728-33. PMID: 2256765.
    Citations: 3     Fields:    Translation:AnimalsCells
  91. Goldman G, Welbourn R, Klausner JM, Alexander S, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Attenuation of acid aspiration edema with phalloidin. Am J Physiol. 1990 Dec; 259(6 Pt 1):L378-83. PMID: 2260672.
    Citations: 2     Fields:    Translation:AnimalsCells
  92. Morel NM, Petruzzo PP, Hechtman HB, Shepro D. Inflammatory agonists that increase microvascular permeability in vivo stimulate cultured pulmonary microvessel endothelial cell contraction. Inflammation. 1990 Oct; 14(5):571-83. PMID: 2174409.
    Citations: 19     Fields:    Translation:AnimalsCells
  93. Goldman G, Welbourn R, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Tumor necrosis factor-alpha mediates acid aspiration-induced systemic organ injury. Ann Surg. 1990 Oct; 212(4):513-9; discussion 519-20. PMID: 2222016.
    Citations: 12     Fields:    Translation:AnimalsCells
  94. Welbourn R, Goldman G, Kobzik L, Paterson I, Valeri CR, Shepro D, Hechtman HB. Neutrophil adherence receptors (CD 18) in ischemia. Dissociation between quantitative cell surface expression and diapedesis mediated by leukotriene B4. J Immunol. 1990 Sep 15; 145(6):1906-11. PMID: 1975261.
    Citations: 10     Fields:    Translation:AnimalsCells
  95. Patton WF, Yoon MU, Alexander JS, Chung-Welch N, Hechtman HB, Shepro D. Expression of simple epithelial cytokeratins in bovine pulmonary microvascular endothelial cells. J Cell Physiol. 1990 Apr; 143(1):140-9. PMID: 1690741.
    Citations: 9     Fields:    Translation:Animals
  96. Goldman G, Welbourn R, Paterson IS, Klausner JM, Kobzik L, Valeri CR, Shepro D, Hechtman HB. Ischemia-induced neutrophil activation and diapedesis is lipoxygenase dependent. Surgery. 1990 Apr; 107(4):428-33. PMID: 2157300.
    Citations: 5     Fields:    Translation:AnimalsCells
  97. Mineau-Hanschke R, Wiles ME, Morel N, Hechtman HB, Shepro D. Modulation of cultured pulmonary microvessel and arterial endothelial cell barrier structure and function by serotonin. Microvasc Res. 1990 Mar; 39(2):140-55. PMID: 2352486.
    Citations: