Harvard Catalyst Profiles

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Dana Gabuzda, M.D.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R56MH115853 (GABUZDA, DANA H.) Sep 23, 2019 - Sep 22, 2021
    CNS Viral Escape in HIV-infected Adults
    Role: Principal Investigator
  2. R01DA046203 (GABUZDA, DANA H.) Apr 1, 2018 - Feb 28, 2023
    Effects of marijuana use on inflammation and vascular injury in adults with HIV infection
    Role: Principal Investigator
  3. R01MH110259 (GABUZDA, DANA H.) Mar 18, 2016 - Jan 31, 2022
    Neuroimmune mechanisms of depression in adults with HIV infection
    Role: Principal Investigator
  4. R01DA040391 (GABUZDA, DANA H.) May 1, 2015 - Feb 28, 2021
    Stress response networks in HIV infection
    Role: Principal Investigator
  5. R01MH097659 (GABUZDA, DANA H.) Aug 1, 2012 - Jul 31, 2019
    Systems Biology of Cognitive Decline in Older Adults with HIV Infection
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Spatola M, Loos C, Cizmeci D, Webb N, Gorman MJ, Rossignol E, Shin S, Yuan D, Fontana L, Mukerji SS, Lauffenburger DA, Gabuzda D, Alter G. Functional Compartmentalization of Antibodies in the Central Nervous System During Chronic HIV Infection. J Infect Dis. 2022 09 04; 226(4):738-750. PMID: 35417540; PMCID: PMC9441210.
    Citations:    Fields:    
  2. Lorenz DR, Mukerji SS, Misra V, Uno H, Gelman BB, Moore DJ, Singer EJ, Morgello S, Gabuzda D. Predictors of Transition to Frailty in Middle-Aged and Older People With HIV: A Prospective Cohort Study. J Acquir Immune Defic Syndr. 2021 12 15; 88(5):518-527. PMID: 34757975; PMCID: PMC8589117.
    Citations: 1     Fields:    Translation:Humans
  3. Lorenz DR, Mukerji SS, Misra V, Uno H, Gelman BB, Moore DJ, Singer EJ, Morgello S, Gabuzda D. Multimorbidity networks associated with frailty among middle-aged and older people with HIV. AIDS. 2021 12 01; 35(15):2451-2461. PMID: 34324449; PMCID: PMC8649075.
    Citations:    Fields:    Translation:Humans
  4. Mukerji SS, Misra V, Lorenz DR, Chettimada S, Keller K, Letendre S, Ellis RJ, Morgello S, Parker RA, Gabuzda D. Low Neuroactive Steroids Identifies a Biological Subtype of Depression in Adults with Human Immunodeficiency Virus on Suppressive Antiretroviral Therapy. J Infect Dis. 2021 05 20; 223(9):1601-1611. PMID: 32157292; PMCID: PMC8136979.
    Citations: 6     Fields:    Translation:Humans
  5. Aldersley J, Lorenz DR, Mouw KW, D'Andrea AD, Gabuzda D. Genomic Landscape of Primary and Recurrent Anal Squamous Cell Carcinomas in Relation to HPV Integration, Copy-Number Variation, and DNA Damage Response Genes. Mol Cancer Res. 2021 08; 19(8):1308-1321. PMID: 33883185; PMCID: PMC8349846.
    Citations: 2     Fields:    Translation:HumansCells
  6. Zhang S, Nguyen HT, Ding H, Wang J, Zou S, Liu L, Guha D, Gabuzda D, Ho DD, Kappes JC, Sodroski J. Dual Pathways of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Trafficking Modulate the Selective Exclusion of Uncleaved Oligomers from Virions. J Virol. 2021 01 13; 95(3). PMID: 33148792.
    Citations: 11     Fields:    Translation:HumansCells
  7. Lorenz DR, Misra V, Chettimada S, Uno H, Wang L, Blount BC, De Jesús VR, Gelman BB, Morgello S, Wolinsky SM, Gabuzda D. Acrolein and other toxicant exposures in relation to cardiovascular disease among marijuana and tobacco smokers in a longitudinal cohort of HIV-positive and negative adults. EClinicalMedicine. 2021 Jan; 31:100697. PMID: 33554087; PMCID: PMC7846668.
    Citations: 3     
  8. Pahwa S, Deeks S, Zou S, Tomitch N, Miller-Novak L, Caler E, Justice A, Sacktor N, Gabuzda D, Hunt PW, Brown T, Kurth A, Baral S, Mugavero M, Mayer KH, Mendenhall E, Detels R, Mutabazi V. NIH Workshop on HIV-Associated Comorbidities, Coinfections, and Complications: Summary and Recommendation for Future Research. J Acquir Immune Defic Syndr. 2021 01 01; 86(1):11-18. PMID: 33306561; PMCID: PMC7982002.
    Citations: 1     Fields:    Translation:Humans
  9. Chettimada S, Lorenz DR, Misra V, Wolinsky SM, Gabuzda D. Small RNA sequencing of extracellular vesicles identifies circulating miRNAs related to inflammation and oxidative stress in HIV patients. BMC Immunol. 2020 11 11; 21(1):57. PMID: 33176710; PMCID: PMC7656686.
    Citations: 11     Fields:    Translation:HumansCells
  10. Gabuzda D, McArthur JC, Letendre SL. Efficacy and safety of two-drug regimens for treatment of HIV in the central nervous system. AIDS. 2020 11 01; 34(13):1975-1977. PMID: 33009012; PMCID: PMC7536841.
    Citations:    Fields:    Translation:HumansCells
  11. Gabuzda D, Jamieson BD, Collman RG, Lederman MM, Burdo TH, Deeks SG, Dittmer DP, Fox HS, Funderburg NT, Pahwa SG, Pandrea I, Wilson CC, Hunt PW. Pathogenesis of Aging and Age-related Comorbidities in People with HIV: Highlights from the HIV ACTION Workshop. Pathog Immun. 2020; 5(1):143-174. PMID: 32856008.
    Citations: 7     
  12. Guha D, Lorenz DR, Misra V, Chettimada S, Morgello S, Gabuzda D. Proteomic analysis of cerebrospinal fluid extracellular vesicles reveals synaptic injury, inflammation, and stress response markers in HIV patients with cognitive impairment. J Neuroinflammation. 2019 Dec 05; 16(1):254. PMID: 31805958; PMCID: PMC6896665.
    Citations: 31     Fields:    Translation:HumansCells
  13. Lorenz DR, Misra V, Gabuzda D. Transcriptomic analysis of monocytes from HIV-positive men on antiretroviral therapy reveals effects of tobacco smoking on interferon and stress response systems associated with depressive symptoms. Hum Genomics. 2019 11 28; 13(1):59. PMID: 31779701; PMCID: PMC6883692.
    Citations: 2     Fields:    Translation:HumansCells
  14. Solomon IH, Chettimada S, Misra V, Lorenz DR, Gorelick RJ, Gelman BB, Morgello S, Gabuzda D. White Matter Abnormalities Linked to Interferon, Stress Response, and Energy Metabolism Gene Expression Changes in Older HIV-Positive Patients on Antiretroviral Therapy. Mol Neurobiol. 2020 Feb; 57(2):1115-1130. PMID: 31691183.
    Citations: 5     Fields:    Translation:HumansCells
  15. Guha D, Mukerji SS, Chettimada S, Misra V, Lorenz DR, Morgello S, Gabuzda D. Cerebrospinal fluid extracellular vesicles and neurofilament light protein as biomarkers of central nervous system injury in HIV-infected patients on antiretroviral therapy. AIDS. 2019 03 15; 33(4):615-625. PMID: 30557159; PMCID: PMC6399073.
    Citations: 19     Fields:    Translation:HumansCells
  16. Aldersley J, Lorenz DR, Misra V, Uno H, Gabuzda D. Increased risk of anal squamous cell carcinoma in HIV-positive men with prior hepatitis B virus infection. AIDS. 2019 01 27; 33(1):145-152. PMID: 30325778; PMCID: PMC6279494.
    Citations: 6     Fields:    Translation:Humans
  17. Lorenz DR, Uno H, Wolinsky SM, Gabuzda D. Effect of marijuana smoking on pulmonary disease in HIV-infected and uninfected men: a longitudinal cohort study. EClinicalMedicine. 2019 Jan; 7:55-64. PMID: 30854514; PMCID: PMC6402353.
    Citations: 9     
  18. Lorenz DR, Uno H, Wolinsky SM, Gabuzda D. Effect of marijuana smoking on pulmonary disease in HIV-infected and uninfected men: a longitudinal cohort study. EClinicalMedicine. 2019; Jan 24. View Publication.
  19. Dutta A, Uno H, Lorenz DR, Wolinsky SM, Gabuzda D. Low T-cell subsets prior to development of virus-associated cancer in HIV-seronegative men who have sex with men. Cancer Causes Control. 2018 Nov; 29(11):1131-1142. PMID: 30315476; PMCID: PMC6245112.
    Citations: 3     Fields:    Translation:HumansCells
  20. Mukerji SS, Misra V, Lorenz DR, Uno H, Morgello S, Franklin D, Ellis RJ, Letendre S, Gabuzda D. Impact of Antiretroviral Regimens on Cerebrospinal Fluid Viral Escape in a Prospective Multicohort Study of Antiretroviral Therapy-Experienced Human Immunodeficiency Virus-1-Infected Adults in the United States. Clin Infect Dis. 2018 09 28; 67(8):1182-1190. PMID: 29617912; PMCID: PMC6160603.
    Citations: 17     Fields:    Translation:HumansCells
  21. Chettimada S, Lorenz DR, Misra V, Dillon ST, Reeves RK, Manickam C, Morgello S, Kirk GD, Mehta SH, Gabuzda D. Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy. Sci Rep. 2018 05 08; 8(1):7227. PMID: 29740045.
    Citations: 69     Fields:    Translation:HumansCells
  22. Gumber S, Amancha PK, Yen PJ, Villinger F, Gabuzda D, Byrareddy SN. In vivo characterization of macrophage-tropic simian immunodeficiency virus molecular clones in rhesus macaques. J Neurovirol. 2018 08; 24(4):411-419. PMID: 29594984; PMCID: PMC6105460.
    Citations:    Fields:    Translation:AnimalsCells
  23. Lorenz DR, Dutta A, Mukerji SS, Holman A, Uno H, Gabuzda D. Marijuana Use Impacts Midlife Cardiovascular Events in HIV-Infected Men. Clin Infect Dis. 2017 Aug 15; 65(4):626-635. PMID: 28449059; PMCID: PMC5850013.
    Citations: 14     Fields:    Translation:Humans
  24. Mukerji S, Haghighat R, Misra V, Lorenz DR, Holman A, Dutta A, Gabuzda D. Longitudinal Modeling of Depressive Trajectories Among HIV-Infected Men Using Cocaine. AIDS Behav. 2017 Jul; 21(7):1985-1995. PMID: 28550378.
    Citations: 5     Fields:    Translation:Humans
  25. Mukerji SS, Misra V, Lorenz D, Cervantes-Arslanian AM, Lyons J, Chalkias S, Wurcel A, Burke D, Venna N, Morgello S, Koralnik IJ, Gabuzda D. Temporal Patterns and Drug Resistance in CSF Viral Escape Among ART-Experienced HIV-1 Infected Adults. J Acquir Immune Defic Syndr. 2017 06 01; 75(2):246-255. PMID: 28328546; PMCID: PMC5452976.
    Citations: 19     Fields:    Translation:HumansCells
  26. Dutta A, Uno H, Holman A, Lorenz DR, Wolinsky SM, Gabuzda D. Long-term nitrite inhalant exposure and cancer risk in MSM. AIDS. 2017 05 15; 31(8):1169-1180. PMID: 28441176; PMCID: PMC5414542.
    Citations: 2     Fields:    Translation:Humans
  27. Dutta A, Uno H, Holman A, Lorenz DR, Gabuzda D. Racial differences in prostate cancer risk in young HIV-positive and HIV-negative men: a prospective cohort study. Cancer Causes Control. 2017 Jul; 28(7):767-777. PMID: 28451806; PMCID: PMC5557016.
    Citations: 3     Fields:    Translation:Humans
  28. Solomon IH, De Girolami U, Chettimada S, Misra V, Singer EJ, Gabuzda D. Brain and liver pathology, amyloid deposition, and interferon responses among older HIV-positive patients in the late HAART era. BMC Infect Dis. 2017 02 17; 17(1):151. PMID: 28212619; PMCID: PMC5316187.
    Citations: 15     Fields:    Translation:HumansCells
  29. Joseph J, Cinque P, Colosi D, Dravid A, Ene L, Fox H, Gabuzda D, Gisslen M, Beth Joseph S, Letendre S, Mukerji SS, Nath A, Perez-Valero I, Persaud D, Price RW, Rao VR, Sacktor N, Swanstrom R, Winston A, Wojna V, Wright E, Spudich S. Highlights of the Global HIV-1 CSF Escape Consortium Meeting, 9 June 2016, Bethesda, MD, USA. J Virus Erad. 2016 Oct 05; 2(4):243-250. PMID: 27781109; PMCID: PMC5075354.
    Citations: 16     
  30. Mukerji SS, Locascio JJ, Misra V, Lorenz DR, Holman A, Dutta A, Penugonda S, Wolinsky SM, Gabuzda D. Lipid Profiles and APOE4 Allele Impact Midlife Cognitive Decline in HIV-Infected Men on Antiretroviral Therapy. Clin Infect Dis. 2016 10 15; 63(8):1130-1139. PMID: 27448678; PMCID: PMC5036920.
    Citations: 15     Fields:    Translation:Humans
  31. Pery E, Sheehy A, Miranda Nebane N, Misra V, Mankowski MK, Rasmussen L, Lucile White E, Ptak RG, Gabuzda D. Redoxal, an inhibitor of de novo pyrimidine biosynthesis, augments APOBEC3G antiviral activity against human immunodeficiency virus type 1. Virology. 2015 Oct; 484:276-287. PMID: 26141568.
    Citations: 4     Fields:    Translation:HumansCells
  32. Cassol E, Misra V, Morgello S, Kirk GD, Mehta SH, Gabuzda D. Altered Monoamine and Acylcarnitine Metabolites in HIV-Positive and HIV-Negative Subjects With Depression. J Acquir Immune Defic Syndr. 2015 May 01; 69(1):18-28. PMID: 25942456; PMCID: PMC4562456.
    Citations: 20     Fields:    Translation:Humans
  33. Mefford ME, Kunstman K, Wolinsky SM, Gabuzda D. Bioinformatic analysis of neurotropic HIV envelope sequences identifies polymorphisms in the gp120 bridging sheet that increase macrophage-tropism through enhanced interactions with CCR5. Virology. 2015 Jul; 481:210-22. PMID: 25797607.
    Citations: 9     Fields:    Translation:HumansCells
  34. Pery E, Sheehy A, Nebane NM, Brazier AJ, Misra V, Rajendran KS, Buhrlage SJ, Mankowski MK, Rasmussen L, White EL, Ptak RG, Gabuzda D. Identification of a novel HIV-1 inhibitor targeting Vif-dependent degradation of human APOBEC3G protein. J Biol Chem. 2015 Apr 17; 290(16):10504-17. PMID: 25724652.
    Citations: 16     Fields:    Translation:HumansCells
  35. Cassol E, Misra V, Dutta A, Morgello S, Gabuzda D. Cerebrospinal fluid metabolomics reveals altered waste clearance and accelerated aging in HIV patients with neurocognitive impairment. AIDS. 2014 Jul 17; 28(11):1579-91. PMID: 24752083; PMCID: PMC4086755.
    Citations: 69     Fields:    Translation:Humans
  36. Yen PJ, Mefford ME, Hoxie JA, Williams KC, Desrosiers RC, Gabuzda D. Identification and characterization of a macrophage-tropic SIV envelope glycoprotein variant in blood from early infection in SIVmac251-infected macaques. Virology. 2014 Jun; 458-459:53-68. PMID: 24928039.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  37. Yen PJ, Herschhorn A, Haim H, Salas I, Gu C, Sodroski J, Gabuzda D. Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission. J Virol. 2014 May; 88(9):5014-28. PMID: 24554659.
    Citations: 10     Fields:    Translation:AnimalsCells
  38. Cassol E, Misra V, Morgello S, Gabuzda D. Applications and limitations of inflammatory biomarkers for studies on neurocognitive impairment in HIV infection. J Neuroimmune Pharmacol. 2013 Dec; 8(5):1087-97. PMID: 24259252.
    Citations: 25     Fields:    Translation:Humans
  39. Cassol E, Misra V, Holman A, Kamat A, Morgello S, Gabuzda D. Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors. BMC Infect Dis. 2013 May 04; 13:203. PMID: 23641933.
    Citations: 61     Fields:    Translation:Humans
  40. Gabuzda D, Yankner BA. Physiology: Inflammation links ageing to the brain. Nature. 2013 May 09; 497(7448):197-8. PMID: 23636321.
    Citations: 27     Fields:    Translation:Animals
  41. Cassol E, Cassetta L, Rizzi C, Gabuzda D, Alfano M, Poli G. Dendritic cell-specific intercellular adhesion molecule-3 grabbing nonintegrin mediates HIV-1 infection of and transmission by M2a-polarized macrophages in vitro. AIDS. 2013 Mar 13; 27(5):707-16. PMID: 23211775; PMCID: PMC5520963.
    Citations: 12     Fields:    Translation:HumansCells
  42. Holman AG, Gabuzda D. A machine learning approach for identifying amino acid signatures in the HIV env gene predictive of dementia. PLoS One. 2012; 7(11):e49538. PMID: 23166702.
    Citations: 11     Fields:    Translation:HumansCells
  43. Kamat A, Lyons JL, Misra V, Uno H, Morgello S, Singer EJ, Gabuzda D. Monocyte activation markers in cerebrospinal fluid associated with impaired neurocognitive testing in advanced HIV infection. J Acquir Immune Defic Syndr. 2012 Jul 01; 60(3):234-43. PMID: 22569268; PMCID: PMC3383928.
    Citations: 114     Fields:    Translation:HumansCells
  44. Mukerji J, Olivieri KC, Misra V, Agopian KA, Gabuzda D. Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation. Retrovirology. 2012 Jun 22; 9:33. PMID: 22534017.
    Citations: 49     Fields:    Translation:HumansCells
  45. Yan Z, Shah PK, Amin SB, Samur MK, Huang N, Wang X, Misra V, Ji H, Gabuzda D, Li C. Integrative analysis of gene and miRNA expression profiles with transcription factor-miRNA feed-forward loops identifies regulators in human cancers. Nucleic Acids Res. 2012 Sep 01; 40(17):e135. PMID: 22645320.
    Citations: 50     Fields:    Translation:HumansCells
  46. Kamat A, Misra V, Cassol E, Ancuta P, Yan Z, Li C, Morgello S, Gabuzda D. A plasma biomarker signature of immune activation in HIV patients on antiretroviral therapy. PLoS One. 2012; 7(2):e30881. PMID: 22363505.
    Citations: 68     Fields:    Translation:Humans
  47. Lyons JL, Uno H, Ancuta P, Kamat A, Moore DJ, Singer EJ, Morgello S, Gabuzda D. Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection. J Acquir Immune Defic Syndr. 2011 Aug 15; 57(5):371-9. PMID: 21646912; PMCID: PMC3159710.
    Citations: 105     Fields:    Translation:Humans
  48. Olivieri KC, Mukerji J, Gabuzda D. Nef-mediated enhancement of cellular activation and human immunodeficiency virus type 1 replication in primary T cells is dependent on association with p21-activated kinase 2. Retrovirology. 2011 Aug 05; 8:64. PMID: 21819585.
    Citations: 12     Fields:    Translation:HumansCells
  49. Holman AG, Mefford ME, O'Connor N, Gabuzda D. HIVBrainSeqDB: a database of annotated HIV envelope sequences from brain and other anatomical sites. AIDS Res Ther. 2010 Dec 14; 7:43. PMID: 21156070.
    Citations: 18     Fields:    
  50. Gray LR, Gabuzda D, Cowley D, Ellett A, Chiavaroli L, Wesselingh SL, Churchill MJ, Gorry PR. CD4 and MHC class 1 down-modulation activities of nef alleles from brain- and lymphoid tissue-derived primary HIV-1 isolates. J Neurovirol. 2011 Feb; 17(1):82-91. PMID: 21165790.
    Citations: 22     Fields:    Translation:HumansCells
  51. Kamat A, Ancuta P, Blumberg RS, Gabuzda D. Serological markers for inflammatory bowel disease in AIDS patients with evidence of microbial translocation. PLoS One. 2010 Nov 15; 5(11):e15533. PMID: 21125014.
    Citations: 15     Fields:    Translation:HumansAnimals
  52. Olivieri KC, Agopian KA, Mukerji J, Gabuzda D. Evidence for adaptive evolution at the divergence between lymphoid and brain HIV-1 nef genes. AIDS Res Hum Retroviruses. 2010 Apr; 26(4):495-500. PMID: 20377428; PMCID: PMC2933169.
    Citations: 15     Fields:    Translation:HumansCells
  53. Ancuta P, Liu KY, Misra V, Wacleche VS, Gosselin A, Zhou X, Gabuzda D. Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets. BMC Genomics. 2009 Aug 27; 10:403. PMID: 19712453.
    Citations: 110     Fields:    Translation:HumansCells
  54. Dunfee RL, Thomas ER, Gabuzda D. Enhanced macrophage tropism of HIV in brain and lymphoid tissues is associated with sensitivity to the broadly neutralizing CD4 binding site antibody b12. Retrovirology. 2009 Jul 20; 6:69. PMID: 19619305.
    Citations: 31     Fields:    Translation:HumansCells
  55. Joseph J, Clifford D, Douglas SD, Fox H, Gendelman HE, Gonzalez-Scarano F, Grant I, Major E, McArthur J. Planning Future Strategies for Domestic and International NeuroAIDS Research, July 24-25, 2008. J Neuroimmune Pharmacol. 2009 Sep; 4(3):283-97. PMID: 19455426; PMCID: PMC2719735.
    Citations: 3     Fields:    Translation:HumansCells
  56. Haim H, Si Z, Madani N, Wang L, Courter JR, Princiotto A, Kassa A, DeGrace M, McGee-Estrada K, Mefford M, Gabuzda D, Smith AB, Sodroski J. Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state. PLoS Pathog. 2009 Apr; 5(4):e1000360. PMID: 19343205.
    Citations: 109     Fields:    Translation:HumansAnimalsCells
  57. Gray L, Roche M, Churchill MJ, Sterjovski J, Ellett A, Poumbourios P, Sherieff S, Sheffief S, Wang B, Saksena N, Purcell DF, Wesselingh S, Cunningham AL, Brew BJ, Gabuzda D, Gorry PR. Tissue-specific sequence alterations in the human immunodeficiency virus type 1 envelope favoring CCR5 usage contribute to persistence of dual-tropic virus in the brain. J Virol. 2009 Jun; 83(11):5430-41. PMID: 19321618.
    Citations: 38     Fields:    Translation:HumansCells
  58. Pery E, Rajendran KS, Brazier AJ, Gabuzda D. Regulation of APOBEC3 proteins by a novel YXXL motif in human immunodeficiency virus type 1 Vif and simian immunodeficiency virus SIVagm Vif. J Virol. 2009 Mar; 83(5):2374-81. PMID: 19109396.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  59. Loerch PM, Lu T, Dakin KA, Vann JM, Isaacs A, Geula C, Wang J, Pan Y, Gabuzda DH, Li C, Prolla TA, Yankner BA. Evolution of the aging brain transcriptome and synaptic regulation. PLoS One. 2008 Oct 02; 3(10):e3329. PMID: 18830410; PMCID: PMC2553198.
    Citations: 147     Fields:    Translation:HumansAnimalsCells
  60. Mefford ME, Gorry PR, Kunstman K, Wolinsky SM, Gabuzda D. Bioinformatic prediction programs underestimate the frequency of CXCR4 usage by R5X4 HIV type 1 in brain and other tissues. AIDS Res Hum Retroviruses. 2008 Sep; 24(9):1215-20. PMID: 18788913; PMCID: PMC2801411.
    Citations: 20     Fields:    Translation:HumansCells
  61. Ancuta P, Kamat A, Kunstman KJ, Kim EY, Autissier P, Wurcel A, Zaman T, Stone D, Mefford M, Morgello S, Singer EJ, Wolinsky SM, Gabuzda D. Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. PLoS One. 2008 Jun 25; 3(6):e2516. PMID: 18575590.
    Citations: 276     Fields:    Translation:HumansCells
  62. Wang J, Shackelford JM, Selliah N, Shivers DK, O'Neill E, Garcia JV, Muthumani K, Weiner D, Yu XF, Gabuzda D, Finkel TH. The HIV-1 Vif protein mediates degradation of Vpr and reduces Vpr-induced cell cycle arrest. DNA Cell Biol. 2008 May; 27(5):267-77. PMID: 18462066.
    Citations: 14     Fields:    Translation:HumansCells
  63. Sterjovski J, Churchill MJ, Ellett A, Gray LR, Roche MJ, Dunfee RL, Purcell DF, Saksena N, Wang B, Sonza S, Wesselingh SL, Karlsson I, Fenyo EM, Gabuzda D, Cunningham AL, Gorry PR. Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS. Retrovirology. 2007 Dec 12; 4:89. PMID: 18076768.
    Citations: 59     Fields:    Translation:HumansCells
  64. Mehle A, Wilson H, Zhang C, Brazier AJ, McPike M, Pery E, Gabuzda D. Identification of an APOBEC3G binding site in human immunodeficiency virus type 1 Vif and inhibitors of Vif-APOBEC3G binding. J Virol. 2007 Dec; 81(23):13235-41. PMID: 17898068; PMCID: PMC2169136.
    Citations: 58     Fields:    Translation:HumansCells
  65. Gorry PR, McPhee DA, Verity E, Dyer WB, Wesselingh SL, Learmont J, Sullivan JS, Roche M, Zaunders JJ, Gabuzda D, Crowe SM, Mills J, Lewin SR, Brew BJ, Cunningham AL, Churchill MJ. Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo. Retrovirology. 2007 Sep 23; 4:66. PMID: 17888184.
    Citations: 42     Fields:    Translation:HumansCells
  66. Gray L, Churchill MJ, Sterjovski J, Witlox K, Learmont JC, Sullivan JS, Wesselingh SL, Gabuzda D, Cunningham AL, McPhee DA, Gorry PR. Phenotype and envelope gene diversity of nef-deleted HIV-1 isolated from long-term survivors infected from a single source. Virol J. 2007 Jul 16; 4:75. PMID: 17634131; PMCID: PMC1939844.
    Citations: 12     Fields:    Translation:HumansCells
  67. Dunfee RL, Thomas ER, Wang J, Kunstman K, Wolinsky SM, Gabuzda D. Loss of the N-linked glycosylation site at position 386 in the HIV envelope V4 region enhances macrophage tropism and is associated with dementia. Virology. 2007 Oct 10; 367(1):222-34. PMID: 17599380.
    Citations: 62     Fields:    Translation:HumansAnimalsCells
  68. Verity EE, Zotos D, Wilson K, Chatfield C, Lawson VA, Dwyer DE, Cunningham A, Learmont J, Dyer W, Sullivan J, Churchill M, Wesselingh SL, Gabuzda D, Gorry PR, McPhee DA. Viral phenotypes and antibody responses in long-term survivors infected with attenuated human immunodeficiency virus type 1 containing deletions in the nef and long terminal repeat regions. J Virol. 2007 Sep; 81(17):9268-78. PMID: 17567690; PMCID: PMC1951448.
    Citations: 12     Fields:    Translation:HumansCells
  69. Thomas ER, Dunfee RL, Stanton J, Bogdan D, Kunstman K, Wolinsky SM, Gabuzda D. High frequency of defective vpu compared with tat and rev genes in brain from patients with HIV type 1-associated dementia. AIDS Res Hum Retroviruses. 2007 Apr; 23(4):575-80. PMID: 17451348.
    Citations: 14     Fields:    Translation:HumansCells
  70. Gorry PR, Dunfee RL, Mefford ME, Kunstman K, Morgan T, Moore JP, Mascola JR, Agopian K, Holm GH, Mehle A, Taylor J, Farzan M, Wang H, Ellery P, Willey SJ, Clapham PR, Wolinsky SM, Crowe SM, Gabuzda D. Changes in the V3 region of gp120 contribute to unusually broad coreceptor usage of an HIV-1 isolate from a CCR5 Delta32 heterozygote. Virology. 2007 May 25; 362(1):163-78. PMID: 17239419.
    Citations: 28     Fields:    Translation:HumansCells
  71. Wang J, Gabuzda D. Reconstitution of human immunodeficiency virus-induced neurodegeneration using isolated populations of human neurons, astrocytes, and microglia and neuroprotection mediated by insulin-like growth factors. J Neurovirol. 2006 Dec; 12(6):472-91. PMID: 17162663.
    Citations: 11     Fields:    Translation:HumansCells
  72. Thomas ER, Dunfee RL, Stanton J, Bogdan D, Taylor J, Kunstman K, Bell JE, Wolinsky SM, Gabuzda D. Macrophage entry mediated by HIV Envs from brain and lymphoid tissues is determined by the capacity to use low CD4 levels and overall efficiency of fusion. Virology. 2007 Mar 30; 360(1):105-19. PMID: 17084877; PMCID: PMC1890014.
    Citations: 83     Fields:    Translation:HumansAnimalsCells
  73. Ancuta P, Wang J, Gabuzda D. CD16+ monocytes produce IL-6, CCL2, and matrix metalloproteinase-9 upon interaction with CX3CL1-expressing endothelial cells. J Leukoc Biol. 2006 Nov; 80(5):1156-64. PMID: 17056766.
    Citations: 71     Fields:    Translation:HumansCells
  74. Dunfee RL, Thomas ER, Gorry PR, Wang J, Taylor J, Kunstman K, Wolinsky SM, Gabuzda D. The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia. Proc Natl Acad Sci U S A. 2006 Oct 10; 103(41):15160-5. PMID: 17015824; PMCID: PMC1586182.
    Citations: 111     Fields:    Translation:HumansCells
  75. Agopian K, Wei BL, Garcia JV, Gabuzda D. CD4 and MHC-I downregulation are conserved in primary HIV-1 Nef alleles from brain and lymphoid tissues, but Pak2 activation is highly variable. Virology. 2007 Feb 05; 358(1):119-35. PMID: 16979207; PMCID: PMC1995023.
    Citations: 16     Fields:    Translation:HumansCells
  76. Dunfee R, Thomas ER, Gorry PR, Wang J, Ancuta P, Gabuzda D. Mechanisms of HIV-1 neurotropism. Curr HIV Res. 2006 Jul; 4(3):267-78. PMID: 16842080.
    Citations: 55     Fields:    Translation:HumansAnimalsCells
  77. Reche PA, Keskin DB, Hussey RE, Ancuta P, Gabuzda D, Reinherz EL. Elicitation from virus-naive individuals of cytotoxic T lymphocytes directed against conserved HIV-1 epitopes. Med Immunol. 2006 May 18; 5:1. PMID: 16674822.
    Citations: 24     
  78. Ancuta P, Autissier P, Wurcel A, Zaman T, Stone D, Gabuzda D. CD16+ monocyte-derived macrophages activate resting T cells for HIV infection by producing CCR3 and CCR4 ligands. J Immunol. 2006 May 15; 176(10):5760-71. PMID: 16670281.
    Citations: 30     Fields:    Translation:HumansCells
  79. Mehle A, Thomas ER, Rajendran KS, Gabuzda D. A zinc-binding region in Vif binds Cul5 and determines cullin selection. J Biol Chem. 2006 Jun 23; 281(25):17259-17265. PMID: 16636053.
    Citations: 109     Fields:    Translation:HumansCells
  80. Gray L, Churchill MJ, Keane N, Sterjovski J, Ellett AM, Purcell DF, Poumbourios P, Kol C, Wang B, Saksena NK, Wesselingh SL, Price P, French M, Gabuzda D, Gorry PR. Genetic and functional analysis of R5X4 human immunodeficiency virus type 1 envelope glycoproteins derived from two individuals homozygous for the CCR5delta32 allele. J Virol. 2006 Apr; 80(7):3684-91. PMID: 16537640; PMCID: PMC1440368.
    Citations: 30     Fields:    Translation:HumansCells
  81. Churchill MJ, Gorry PR, Cowley D, Lal L, Sonza S, Purcell DF, Thompson KA, Gabuzda D, McArthur JC, Pardo CA, Wesselingh SL. Use of laser capture microdissection to detect integrated HIV-1 DNA in macrophages and astrocytes from autopsy brain tissues. J Neurovirol. 2006 Apr; 12(2):146-52. PMID: 16798676.
    Citations: 113     Fields:    Translation:HumansCells
  82. Agopian K, Wei BL, Garcia JV, Gabuzda D. A hydrophobic binding surface on the human immunodeficiency virus type 1 Nef core is critical for association with p21-activated kinase 2. J Virol. 2006 Mar; 80(6):3050-61. PMID: 16501114; PMCID: PMC1395437.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  83. Ancuta P, Kunstman KJ, Autissier P, Zaman T, Stone D, Wolinsky SM, Gabuzda D. CD16+ monocytes exposed to HIV promote highly efficient viral replication upon differentiation into macrophages and interaction with T cells. Virology. 2006 Jan 20; 344(2):267-76. PMID: 16305804.
    Citations: 46     Fields:    Translation:HumansCells
  84. Louder MK, Sambor A, Chertova E, Hunte T, Barrett S, Ojong F, Sanders-Buell E, Zolla-Pazner S, McCutchan FE, Roser JD, Gabuzda D, Lifson JD, Mascola JR. HIV-1 envelope pseudotyped viral vectors and infectious molecular clones expressing the same envelope glycoprotein have a similar neutralization phenotype, but culture in peripheral blood mononuclear cells is associated with decreased neutralization sensitivity. Virology. 2005 Sep 01; 339(2):226-38. PMID: 16005039.
    Citations: 59     Fields:    Translation:HumansCells
  85. Farrow MA, Somasundaran M, Zhang C, Gabuzda D, Sullivan JL, Greenough TC. Nuclear localization of HIV type 1 Vif isolated from a long-term asymptomatic individual and potential role in virus attenuation. AIDS Res Hum Retroviruses. 2005 Jun; 21(6):565-74. PMID: 15989462.
    Citations: 12     Fields:    Translation:HumansCells
  86. Holm GH, Gabuzda D. Distinct mechanisms of CD4+ and CD8+ T-cell activation and bystander apoptosis induced by human immunodeficiency virus type 1 virions. J Virol. 2005 May; 79(10):6299-311. PMID: 15858014; PMCID: PMC1091688.
    Citations: 36     Fields:    Translation:HumansCells
  87. Gorry PR, Churchill M, Crowe SM, Cunningham AL, Gabuzda D. Pathogenesis of macrophage tropic HIV-1. Curr HIV Res. 2005 Jan; 3(1):53-60. PMID: 15638723.
    Citations: 55     Fields:    Translation:HumansCells
  88. Mehle A, Goncalves J, Santa-Marta M, McPike M, Gabuzda D. Phosphorylation of a novel SOCS-box regulates assembly of the HIV-1 Vif-Cul5 complex that promotes APOBEC3G degradation. Genes Dev. 2004 Dec 01; 18(23):2861-6. PMID: 15574592; PMCID: PMC534646.
    Citations: 172     Fields:    Translation:HumansCells
  89. Aires da Silva F, Santa-Marta M, Freitas-Vieira A, Mascarenhas P, Barahona I, Moniz-Pereira J, Gabuzda D, Goncalves J. Camelized rabbit-derived VH single-domain intrabodies against Vif strongly neutralize HIV-1 infectivity. J Mol Biol. 2004 Jul 09; 340(3):525-42. PMID: 15210352.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  90. Wang J, Babcock GJ, Choe H, Farzan M, Sodroski J, Gabuzda D. N-linked glycosylation in the CXCR4 N-terminus inhibits binding to HIV-1 envelope glycoproteins. Virology. 2004 Jun 20; 324(1):140-50. PMID: 15183061.
    Citations: 15     Fields:    Translation:HumansCells
  91. Bobardt MD, Salmon P, Wang L, Esko JD, Gabuzda D, Fiala M, Trono D, Van der Schueren B, David G, Gallay PA. Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion. J Virol. 2004 Jun; 78(12):6567-84. PMID: 15163749; PMCID: PMC416544.
    Citations: 54     Fields:    Translation:HumansCells
  92. Holm GH, Zhang C, Gorry PR, Peden K, Schols D, De Clercq E, Gabuzda D. Apoptosis of bystander T cells induced by human immunodeficiency virus type 1 with increased envelope/receptor affinity and coreceptor binding site exposure. J Virol. 2004 May; 78(9):4541-51. PMID: 15078935; PMCID: PMC387714.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  93. Ancuta P, Moses A, Gabuzda D. Transendothelial migration of CD16+ monocytes in response to fractalkine under constitutive and inflammatory conditions. Immunobiology. 2004; 209(1-2):11-20. PMID: 15481136.
    Citations: 42     Fields:    Translation:HumansCells
  94. Mehle A, Strack B, Ancuta P, Zhang C, McPike M, Gabuzda D. Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway. J Biol Chem. 2004 Feb 27; 279(9):7792-8. PMID: 14672928.
    Citations: 265     Fields:    Translation:HumansCells
  95. Ohagen A, Devitt A, Kunstman KJ, Gorry PR, Rose PP, Korber B, Taylor J, Levy R, Murphy RL, Wolinsky SM, Gabuzda D. Genetic and functional analysis of full-length human immunodeficiency virus type 1 env genes derived from brain and blood of patients with AIDS. J Virol. 2003 Nov; 77(22):12336-45. PMID: 14581570; PMCID: PMC254258.
    Citations: 93     Fields:    Translation:HumansCells
  96. Ancuta P, Rao R, Moses A, Mehle A, Shaw SK, Luscinskas FW, Gabuzda D. Fractalkine preferentially mediates arrest and migration of CD16+ monocytes. J Exp Med. 2003 Jun 16; 197(12):1701-7. PMID: 12810688; PMCID: PMC2193954.
    Citations: 196     Fields:    Translation:HumansCells
  97. Crawford K, Stark A, Kitchens B, Sternheim K, Pantazopoulos V, Triantafellow E, Wang Z, Vasir B, Larsen CE, Gabuzda D, Reinherz E, Alper CA. CD2 engagement induces dendritic cell activation: implications for immune surveillance and T-cell activation. Blood. 2003 Sep 01; 102(5):1745-52. PMID: 12714509.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  98. Gorry PR, Taylor J, Holm GH, Mehle A, Morgan T, Cayabyab M, Farzan M, Wang H, Bell JE, Kunstman K, Moore JP, Wolinsky SM, Gabuzda D. Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate. J Virol. 2002 Jun; 76(12):6277-92. PMID: 12021361; PMCID: PMC136234.
    Citations: 131     Fields:    Translation:HumansCells
  99. Goncalves J, Silva F, Freitas-Vieira A, Santa-Marta M, Malhó R, Yang X, Gabuzda D, Barbas C. Functional neutralization of HIV-1 Vif protein by intracellular immunization inhibits reverse transcription and viral replication. J Biol Chem. 2002 Aug 30; 277(35):32036-45. PMID: 12039955.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  100. Gorry PR, Zhang C, Wu S, Kunstman K, Trachtenberg E, Phair J, Wolinsky S, Gabuzda D. Persistence of dual-tropic HIV-1 in an individual homozygous for the CCR5 Delta 32 allele. Lancet. 2002 May 25; 359(9320):1832-4. PMID: 12044382.
    Citations: 29     Fields:    Translation:HumansCells
  101. Mascola JR, Louder MK, Winter C, Prabhakara R, De Rosa SC, Douek DC, Hill BJ, Gabuzda D, Roederer M. Human immunodeficiency virus type 1 neutralization measured by flow cytometric quantitation of single-round infection of primary human T cells. J Virol. 2002 May; 76(10):4810-21. PMID: 11967298; PMCID: PMC136170.
    Citations: 59     Fields:    Translation:HumansCells
  102. Wang J, Crawford K, Yuan M, Wang H, Gorry PR, Gabuzda D. Regulation of CC chemokine receptor 5 and CD4 expression and human immunodeficiency virus type 1 replication in human macrophages and microglia by T helper type 2 cytokines. J Infect Dis. 2002 Apr 01; 185(7):885-97. PMID: 11920312.
    Citations: 34     Fields:    Translation:HumansCells
  103. Gorry PR, Bristol G, Zack JA, Ritola K, Swanstrom R, Birch CJ, Bell JE, Bannert N, Crawford K, Wang H, Schols D, De Clercq E, Kunstman K, Wolinsky SM, Gabuzda D. Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity. J Virol. 2001 Nov; 75(21):10073-89. PMID: 11581376; PMCID: PMC114582.
    Citations: 161     Fields:    Translation:HumansCells
  104. Ancuta P, Bakri Y, Chomont N, Hocini H, Gabuzda D, Haeffner-Cavaillon N. Opposite effects of IL-10 on the ability of dendritic cells and macrophages to replicate primary CXCR4-dependent HIV-1 strains. J Immunol. 2001 Mar 15; 166(6):4244-53. PMID: 11238678.
    Citations: 12     Fields:    Translation:HumansCells
  105. Ohagen A, Gabuzda D. Role of Vif in stability of the human immunodeficiency virus type 1 core. J Virol. 2000 Dec; 74(23):11055-66. PMID: 11070000; PMCID: PMC113185.
    Citations: 32     Fields:    Translation:HumansCells
  106. Gabuzda D, Wang J. Chemokine receptors and mechanisms of cell death in HIV neuropathogenesis. J Neurovirol. 2000 May; 6 Suppl 1:S24-32. PMID: 10871762.
    Citations: 34     Fields:    Translation:HumansCells
  107. Ohagen A, Li L, Rosenzweig A, Gabuzda D. Cell-dependent mechanisms restrict the HIV type 1 coreceptor activity of US28, a chemokine receptor homolog encoded by human cytomegalovirus. AIDS Res Hum Retroviruses. 2000 Jan 01; 16(1):27-35. PMID: 10628814.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  108. Crawford K, Gabuzda D, Pantazopoulos V, Xu J, Clement C, Reinherz E, Alper CA. Circulating CD2+ monocytes are dendritic cells. J Immunol. 1999 Dec 01; 163(11):5920-8. PMID: 10570278.
    Citations: 21     Fields:    Translation:HumansCells
  109. Gabuzda D, Wang J. Chemokine receptors and virus entry in the central nervous system. J Neurovirol. 1999 Dec; 5(6):643-58. PMID: 10602405.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  110. Yang X, Chen Y, Gabuzda D. ERK MAP kinase links cytokine signals to activation of latent HIV-1 infection by stimulating a cooperative interaction of AP-1 and NF-kappaB. J Biol Chem. 1999 Sep 24; 274(39):27981-8. PMID: 10488148.
    Citations: 78     Fields:    Translation:HumansCells
  111. Yang X, Gabuzda D. Regulation of human immunodeficiency virus type 1 infectivity by the ERK mitogen-activated protein kinase signaling pathway. J Virol. 1999 Apr; 73(4):3460-6. PMID: 10074203; PMCID: PMC104113.
    Citations: 70     Fields:    Translation:HumansCells
  112. Ohagen A, Ghosh S, He J, Huang K, Chen Y, Yuan M, Osathanondh R, Gartner S, Shi B, Shaw G, Gabuzda D. Apoptosis induced by infection of primary brain cultures with diverse human immunodeficiency virus type 1 isolates: evidence for a role of the envelope. J Virol. 1999 Feb; 73(2):897-906. PMID: 9882290; PMCID: PMC103909.
    Citations: 80     Fields:    Translation:HumansAnimalsCells
  113. Luo Y, Kim R, Gabuzda D, Mi S, Collins-Racie LA, Lu Z, Jacobs KA, Dorf ME. The CXC-chemokine, H174: expression in the central nervous system. J Neurovirol. 1998 Dec; 4(6):575-85. PMID: 10065899.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  114. Yang X, Gabuzda D. Mitogen-activated protein kinase phosphorylates and regulates the HIV-1 Vif protein. J Biol Chem. 1998 Nov 06; 273(45):29879-87. PMID: 9792705.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  115. Gabuzda D, He J, Ohagen A, Vallat AV. Chemokine receptors in HIV-1 infection of the central nervous system. Semin Immunol. 1998 Jun; 10(3):203-13. PMID: 9653047.
    Citations: 29     Fields:    Translation:HumansCells
  116. Shi B, Raina J, Lorenzo A, Busciglio J, Gabuzda D. Neuronal apoptosis induced by HIV-1 Tat protein and TNF-alpha: potentiation of neurotoxicity mediated by oxidative stress and implications for HIV-1 dementia. J Neurovirol. 1998 Jun; 4(3):281-90. PMID: 9639071.
    Citations: 62     Fields:    Translation:HumansCells
  117. Vallat AV, De Girolami U, He J, Mhashilkar A, Marasco W, Shi B, Gray F, Bell J, Keohane C, Smith TW, Gabuzda D. Localization of HIV-1 co-receptors CCR5 and CXCR4 in the brain of children with AIDS. Am J Pathol. 1998 Jan; 152(1):167-78. PMID: 9422534; PMCID: PMC1858124.
    Citations: 53     Fields:    Translation:HumansCells
  118. Bouyac M, Courcoul M, Bertoia G, Baudat Y, Gabuzda D, Blanc D, Chazal N, Boulanger P, Sire J, Vigne R, Spire B. Human immunodeficiency virus type 1 Vif protein binds to the Pr55Gag precursor. J Virol. 1997 Dec; 71(12):9358-65. PMID: 9371595; PMCID: PMC230239.
    Citations: 48     Fields:    Translation:HumansCells
  119. Höglund S, Ohagen A, Goncalves J, Panganiban AT, Gabuzda D. Ultrastructure of HIV-1 genomic RNA. Virology. 1997 Jul 07; 233(2):271-9. PMID: 9217051.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  120. He J, deCastro CM, Vandenbark GR, Busciglio J, Gabuzda D. Astrocyte apoptosis induced by HIV-1 transactivation of the c-kit protooncogene. Proc Natl Acad Sci U S A. 1997 Apr 15; 94(8):3954-9. PMID: 9108086; PMCID: PMC20549.
    Citations: 10     Fields:    Translation:HumansCells
  121. He J, Chen Y, Farzan M, Choe H, Ohagen A, Gartner S, Busciglio J, Yang X, Hofmann W, Newman W, Mackay CR, Sodroski J, Gabuzda D. CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia. Nature. 1997 Feb 13; 385(6617):645-9. PMID: 9024664.
    Citations: 328     Fields:    Translation:HumansCells
  122. Goncalves J, Korin Y, Zack J, Gabuzda D. Role of Vif in human immunodeficiency virus type 1 reverse transcription. J Virol. 1996 Dec; 70(12):8701-9. PMID: 8970997; PMCID: PMC190965.
    Citations: 62     Fields:    Translation:HumansCells
  123. Shi B, De Girolami U, He J, Wang S, Lorenzo A, Busciglio J, Gabuzda D. Apoptosis induced by HIV-1 infection of the central nervous system. J Clin Invest. 1996 Nov 01; 98(9):1979-90. PMID: 8903316; PMCID: PMC507641.
    Citations: 74     Fields:    Translation:HumansCells
  124. Yang X, Goncalves J, Gabuzda D. Phosphorylation of Vif and its role in HIV-1 replication. J Biol Chem. 1996 Apr 26; 271(17):10121-9. PMID: 8626571.
    Citations: 41     Fields:    Translation:HumansCells
  125. Goncalves J, Shi B, Yang X, Gabuzda D. Biological activity of human immunodeficiency virus type 1 Vif requires membrane targeting by C-terminal basic domains. J Virol. 1995 Nov; 69(11):7196-204. PMID: 7474141; PMCID: PMC189641.
    Citations: 33     Fields:    Translation:HumansCells
  126. Gabuzda DH, Li H, Lawrence K, Vasir BS, Crawford K, Langhoff E. Essential role of vif in establishing productive HIV-1 infection in peripheral blood T lymphocytes and monocyte/macrophages. J Acquir Immune Defic Syndr (1988). 1994 Sep; 7(9):908-15. PMID: 7519673.
    Citations: 39     Fields:    Translation:HumansCells
  127. Lodge R, Göttlinger H, Gabuzda D, Cohen EA, Lemay G. The intracytoplasmic domain of gp41 mediates polarized budding of human immunodeficiency virus type 1 in MDCK cells. J Virol. 1994 Aug; 68(8):4857-61. PMID: 8035484; PMCID: PMC236425.
    Citations: 87     Fields:    Translation:AnimalsCells
  128. Höglund S, Ohagen A, Lawrence K, Gabuzda D. Role of vif during packing of the core of HIV-1. Virology. 1994 Jun; 201(2):349-55. PMID: 8184544.
    Citations: 51     Fields:    Translation:HumansCells
  129. Gabuzda D, Busciglio J, Chen LB, Matsudaira P, Yankner BA. Inhibition of energy metabolism alters the processing of amyloid precursor protein and induces a potentially amyloidogenic derivative. J Biol Chem. 1994 May 06; 269(18):13623-8. PMID: 8175797.
    Citations: 104     Fields:    Translation:HumansCells
  130. Goncalves J, Jallepalli P, Gabuzda DH. Subcellular localization of the Vif protein of human immunodeficiency virus type 1. J Virol. 1994 Feb; 68(2):704-12. PMID: 8289374; PMCID: PMC236506.
    Citations: 66     Fields:    Translation:AnimalsCells
  131. Clements JE, Zink MC, Narayan O, Gabuzda DH. Lentivirus infection of macrophages. Immunol Ser. 1994; 60:589-600. PMID: 8251596.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  132. Gabuzda D, Busciglio J, Yankner BA. Inhibition of beta-amyloid production by activation of protein kinase C. J Neurochem. 1993 Dec; 61(6):2326-9. PMID: 8245986.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  133. Busciglio J, Gabuzda DH, Matsudaira P, Yankner BA. Generation of beta-amyloid in the secretory pathway in neuronal and nonneuronal cells. Proc Natl Acad Sci U S A. 1993 Mar 01; 90(5):2092-6. PMID: 8446635; PMCID: PMC46027.
    Citations: 121     Fields:    Translation:AnimalsCells
  134. Gabuzda DH, Lawrence K, Langhoff E, Terwilliger E, Dorfman T, Haseltine WA, Sodroski J. Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes. J Virol. 1992 Nov; 66(11):6489-95. PMID: 1357189; PMCID: PMC240141.
    Citations: 200     Fields:    Translation:HumansCells
  135. Repke H, Gabuzda D, Palù G, Emmrich F, Sodroski J. Effects of CD4 synthetic peptides on HIV type I envelope glycoprotein function. J Immunol. 1992 Sep 01; 149(5):1809-16. PMID: 1354681.
    Citations: 11     Fields:    Translation:HumansCells
  136. Gabuzda DH, Lever A, Terwilliger E, Sodroski J. Effects of deletions in the cytoplasmic domain on biological functions of human immunodeficiency virus type 1 envelope glycoproteins. J Virol. 1992 Jun; 66(6):3306-15. PMID: 1583717; PMCID: PMC241108.
    Citations: 115     Fields:    Translation:Cells
  137. Terwilliger EF, Langhoff E, Gabuzda D, Zazopoulos E, Haseltine WA. Allelic variation in the effects of the nef gene on replication of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A. 1991 Dec 01; 88(23):10971-5. PMID: 1720558; PMCID: PMC53054.
    Citations: 37     Fields:    Translation:HumansCells
  138. Thali M, Olshevsky U, Furman C, Gabuzda D, Posner M, Sodroski J. Characterization of a discontinuous human immunodeficiency virus type 1 gp120 epitope recognized by a broadly reactive neutralizing human monoclonal antibody. J Virol. 1991 Nov; 65(11):6188-93. PMID: 1717717; PMCID: PMC250310.
    Citations: 113     Fields:    Translation:AnimalsCells
  139. Thali M, Olshevsky U, Furman C, Gabuzda D, Li J, Sodroski J. Effects of changes in gp120-CD4 binding affinity on human immunodeficiency virus type 1 envelope glycoprotein function and soluble CD4 sensitivity. J Virol. 1991 Sep; 65(9):5007-12. PMID: 1870209; PMCID: PMC248964.
    Citations: 67     Fields:    Translation:AnimalsCells
  140. Gabuzda D, Olshevsky U, Bertani P, Haseltine WA, Sodroski J. Identification of membrane anchorage domains of the HIV-1 gp160 envelope glycoprotein precursor. J Acquir Immune Defic Syndr (1988). 1991; 4(1):34-40. PMID: 1984054.
    Citations: 23     Fields:    Translation:HumansCells
  141. Helseth E, Olshevsky U, Gabuzda D, Ardman B, Haseltine W, Sodroski J. Changes in the transmembrane region of the human immunodeficiency virus type 1 gp41 envelope glycoprotein affect membrane fusion. J Virol. 1990 Dec; 64(12):6314-8. PMID: 2243396; PMCID: PMC248812.
    Citations: 83     Fields:    Translation:AnimalsCells
  142. Gabuzda DH. Neurologic disorders associated with HIV infections. J Am Acad Dermatol. 1990 Jun; 22(6 Pt 2):1232-6. PMID: 2193951.
    Citations: 6     Fields:    Translation:Humans
  143. Clements JE, Gabuzda DH, Gdovin SL. Cell type specific and viral regulation of visna virus gene expression. Virus Res. 1990 Jun; 16(2):175-83. PMID: 2166980.
    Citations: 4     Fields:    Translation:HumansCells
  144. Helseth E, Kowalski M, Gabuzda D, Olshevsky U, Haseltine W, Sodroski J. Rapid complementation assays measuring replicative potential of human immunodeficiency virus type 1 envelope glycoprotein mutants. J Virol. 1990 May; 64(5):2416-20. PMID: 2325207; PMCID: PMC249407.
    Citations: 149     Fields:    Translation:HumansAnimalsCells
  145. Clements JE, Gabuzda D. Cellular regulation of visna virus gene expression and its role in pathogenesis. Dev Biol Stand. 1990; 72:207-12. PMID: 2178118.
    Citations:    Fields:    Translation:AnimalsCells
  146. Gabuzda DH, Hess JL, Small JA, Clements JE. Regulation of the visna virus long terminal repeat in macrophages involves cellular factors that bind sequences containing AP-1 sites. Mol Cell Biol. 1989 Jun; 9(6):2728-33. PMID: 2548087.
    Citations: 25     Fields:    Translation:HumansCells
  147. de la Monte SM, Gabuzda DH, Ho DD, Brown RH, Hedley-Whyte ET, Schooley RT, Hirsch MS, Bhan AK. Peripheral neuropathy in the acquired immunodeficiency syndrome. Ann Neurol. 1988 May; 23(5):485-92. PMID: 2839106.
    Citations: 34     Fields:    Translation:HumansCells
  148. Gabuzda DH, Levy SR, Chiappa KH. Electroencephalography in AIDS and AIDS-related complex. Clin Electroencephalogr. 1988 Jan; 19(1):1-6. PMID: 3396199.
    Citations: 5     Fields:    Translation:Humans
  149. Gabuzda DH, Sobel RA. HIV antigen in brains of patients with AIDS. Ann Neurol. 1987 Nov; 22(5):668. PMID: 3480698.
    Citations: 3     Fields:    Translation:HumansCells
  150. Gabuzda DH, Hirsch MS. Neurologic manifestations of infection with human immunodeficiency virus. Clinical features and pathogenesis. Ann Intern Med. 1987 Sep; 107(3):383-91. PMID: 3039890.
    Citations: 36     Fields:    Translation:HumansAnimals
  151. Gabuzda DH, Frankenburg FR. Fever caused by lithium in a patient with neuroleptic malignant syndrome. J Clin Psychopharmacol. 1987 Aug; 7(4):283-4. PMID: 3624519.
    Citations: 1     Fields:    Translation:Humans
  152. Gabuzda DH, Ho DD, de la Monte SM, Hirsch MS, Rota TR, Sobel RA. Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS. Ann Neurol. 1986 Sep; 20(3):289-95. PMID: 3532930.
    Citations: 93     Fields:    Translation:HumansCells
  153. Yankner BA, Skolnik PR, Shoukimas GM, Gabuzda DH, Sobel RA, Ho DD. Cerebral granulomatous angiitis associated with isolation of human T-lymphotropic virus type III from the central nervous system. Ann Neurol. 1986 Sep; 20(3):362-4. PMID: 3639720.
    Citations: 15     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.