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Nira Pollock, M.D., Ph.D.

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Biography
Yale UniversityBA06/1993Biology
University of California San FranciscoPhD12/1999Biochemistry
University of California San FranciscoMD12/2001
Brigham and Women's HospitalResidency12/2003Internal Medicine
Beth Israel Deaconess Medical CenterFellowship12/2007Infectious Diseases
Harvard/MIT06/2008Clinical Investigator Training Program
Harvard Medical School/MITMMSc06/2008Clinical Research
Beth Israel Deaconess Medical CenterFellowship12/2010CPEP Medical Microbiology Fellowship
Beth Israel Deaconess Medical CenterD(ABMM)08/2011Medical Microbiology

Overview

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AI137229 (CABODI, MARIO) Aug 20, 2018 - Jul 31, 2020
    NIH/NIAID
    A paperfluidic molecular diagnostic for Trichomonas vaginalis
    Role: Co-Principal Investigator
  2. R01AI116596 (POLLOCK, NIRA) Apr 1, 2016 - Mar 31, 2021
    NIH/NIAID
    Ultrasensitive C.difficile toxin measurement for diagnosis and outcome prediction
    Role: Principal Investigator
  3. R21AI119457 (POLLOCK, NIRA) Apr 20, 2015 - Mar 31, 2017
    NIH/NIAID
    Borrelia antigen detection assay for urine-based diagnosis of early Lyme disease
    Role: Principal Investigator
  4. Innovation Grant (Pollock, Nira) Mar 1, 2015 - Dec 31, 2017
    Center for Integration of Medicine and Innovative Technology
    Fingerstick blood collection and dispensation device to enable point-of-care diagnostics
    Role: Principal Investigator
  5. Merieux Research Grant (Pollock, Nira) Jan 1, 2015 - May 14, 2018
    Institut Merieux
    Quantification of C. difficile toxins A and B in the stool of asymptomatic carriers of toxinogenic C. difficile
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Flores JA, Calderón R, Mesman AW, Soto M, Coit J, Aliaga J, Mendoza M, Leon SR, Konda K, Mestanza FM, Mendoza CJ, Lecca L, Murray MB, Holmberg RC, Pollock NR, Franke MF. DETECTION OF MYCOBACTERIUM TUBERCULOSIS DNA IN BUCCAL SWAB SAMPLES FROM CHILDREN IN LIMA, PERU. Pediatr Infect Dis J. 2020 Jul 14. PMID: 32675773.
    Citations:    
  2. Branda JA, Lemieux JE, Blair L, Ahmed AA, Hong DK, Bercovici S, Blauwkamp TA, Hollemon D, Ho C, Strle K, Damle NS, Lepore TJ, Pollock NR. Detection of Borrelia burgdorferi Cell-free DNA in Human Plasma Samples for Improved Diagnosis of Early Lyme Borreliosis. Clin Infect Dis. 2020 Jun 25. PMID: 32584965.
    Citations:    
  3. Lee RA, Al Dhaheri F, Pollock NR, Sharma TS. Assessment of the Clinical Utility of Plasma Metagenomic Next-Generation Sequencing in a Pediatric Hospital Population. J Clin Microbiol. 2020 Jun 24; 58(7). PMID: 32376666.
    Citations:    
  4. Lin Q, Pollock NR, Banz A, Lantz A, Xu H, Gu L, Gerding DN, Garey KW, Gonzales-Luna AJ, Zhao M, Song L, Duffy DC, Kelly CP, Chen X. Toxin A-Predominant Pathogenic Clostridioides difficile: A Novel Clinical Phenotype. Clin Infect Dis. 2020 Jun 10; 70(12):2628-2633. PMID: 31400280.
    Citations:    
  5. Kelly CP, Chen X, Williams D, Xu H, Cuddemi CA, Daugherty K, Barrett C, Miller M, Foussadier A, Lantz A, Banz A, Pollock NR. Host Immune Markers Distinguish Clostridioides difficile Infection From Asymptomatic Carriage and Non-C. difficile Diarrhea. Clin Infect Dis. 2020 Mar 03; 70(6):1083-1093. PMID: 31211839.
    Citations:    
  6. Bulterys MA, Wagner B, Redard-Jacot M, Suresh A, Pollock NR, Moreau E, Denkinger CM, Drain PK, Broger T. Point-Of-Care Urine LAM Tests for Tuberculosis Diagnosis: A Status Update. J Clin Med. 2019 Dec 31; 9(1). PMID: 31906163.
    Citations:    
  7. Brock M, Hanlon D, Zhao M, Pollock NR. Detection of mycobacterial lipoarabinomannan in serum for diagnosis of active tuberculosis. Diagn Microbiol Infect Dis. 2020 Feb; 96(2):114937. PMID: 31785971.
    Citations:    
  8. Mesman AW, Soto M, Coit J, Calderon R, Aliaga J, Pollock NR, Mendoza M, Mestanza FM, Mendoza CJ, Murray MB, Lecca L, Holmberg R, Franke MF. Correction to: Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology. BMC Infect Dis. 2019 10 16; 19(1):856. PMID: 31619179.
    Citations:    
  9. White NC, Mendo-Lopez R, Papamichael K, Cuddemi CA, Barrett C, Daugherty K, Pollock N, Kelly CP, Alonso CD. Laxative use does not preclude diagnosis or reduce disease severity in Clostridiodes difficile infection. Clin Infect Dis. 2019 Oct 04. PMID: 31584632.
    Citations:    
  10. Mesman AW, Soto M, Coit J, Calderon R, Aliaga J, Pollock NR, Mendoza M, Mestanza FM, Mendoza CJ, Murray MB, Lecca L, Holmberg R, Franke MF. Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology. BMC Infect Dis. 2019 Jun 27; 19(1):563. PMID: 31248383.
    Citations:    
  11. Pollock NR, Banz A, Chen X, Williams D, Xu H, Cuddemi CA, Cui AX, Perrotta M, Alhassan E, Riou B, Lantz A, Miller MA, Kelly CP. Comparison of Clostridioides difficile Stool Toxin Concentrations in Adults With Symptomatic Infection and Asymptomatic Carriage Using an Ultrasensitive Quantitative Immunoassay. Clin Infect Dis. 2019 01 01; 68(1):78-86. PMID: 29788296.
    Citations: 1     Fields:    
  12. Roldan GA, Cui AX, Pollock NR. Assessing the Burden of Clostridium difficile Infection in Low- and Middle-Income Countries. J Clin Microbiol. 2018 03; 56(3). PMID: 29305541.
    Citations:    Fields:    
  13. Pollock N, Dhiman R, Daifalla N, Farhat M, Campos-Neto A. Discovery of a unique Mycobacterium tuberculosis protein through proteomic analysis of urine from patients with active tuberculosis. Microbes Infect. 2018 04; 20(4):228-235. PMID: 29306028.
    Citations:    Fields:    
  14. Rajasingham R, Pollock NR, Linas BP. The Cost-effectiveness of a Point-of-Care Paper Transaminase Test for Monitoring Treatment of HIV/TB Co-Infected Persons. Open Forum Infect Dis. 2017; 4(4):ofx194. PMID: 30364559.
    Citations:    
  15. Sauer-Budge AF, Brookfield SJ, Janzen R, McGray S, Boardman A, Wirz H, Pollock NR. A novel device for collecting and dispensing fingerstick blood for point of care testing. PLoS One. 2017; 12(8):e0183625. PMID: 28837616.
    Citations:    Fields:    Translation:Humans
  16. Alawdah LS, Campbell JN, Pollock N, Watnick PI. Erysipelothrix rhusiopathiae Suppurative Arthritis in a 12-year-old Boy After an Unusual Fresh Water Exposure. Pediatr Infect Dis J. 2017 04; 36(4):431-433. PMID: 27977547.
    Citations:    Fields:    Translation:HumansAnimals
  17. Pollock NR, Wonderly B. Evaluating Novel Diagnostics in an Outbreak Setting: Lessons Learned from Ebola. J Clin Microbiol. 2017 05; 55(5):1255-1261. PMID: 28250002.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  18. Broadhurst MJ, Brooks TJ, Pollock NR. Diagnosis of Ebola Virus Disease: Past, Present, and Future. Clin Microbiol Rev. 2016 Oct; 29(4):773-93. PMID: 27413095.
    Citations: 12     Fields:    Translation:Humans
  19. Semper AE, Broadhurst MJ, Richards J, Foster GM, Simpson AJ, Logue CH, Kelly JD, Miller A, Brooks TJ, Murray M, Pollock NR. Performance of the GeneXpert Ebola Assay for Diagnosis of Ebola Virus Disease in Sierra Leone: A Field Evaluation Study. PLoS Med. 2016 Mar; 13(3):e1001980. PMID: 27023868.
    Citations: 12     Fields:    Translation:HumansCells
  20. Semper A, Broadhurst MJ, Richards J, Foster GM, Simpson A, Groppelli E, Johnson J, Kelly JD, Brooks T, Logue CH, Miller A, Murray M, Pollock NR. Field Laboratory Evaluation of the GeneXpert Ebola Assay for Diagnosis of Ebola Virus Disease in Sierra Leone. Open Forum Infect Dis. 2015 Dec; 2(Suppl 1). PMID: 27437423.
    Citations:    
  21. Pollock NR. Ultrasensitive Detection and Quantification of Toxins for Optimized Diagnosis of Clostridium difficile Infection. J Clin Microbiol. 2016 Feb; 54(2):259-64. PMID: 26659205.
    Citations: 4     Fields:    Translation:HumansCells
  22. Broadhurst MJ, Semper A, Bailey D, Pollock NR. ReEBOV Antigen Rapid Test kit for Ebola - Authors' reply. Lancet. 2015 Dec 05; 386(10010):2255-6. PMID: 26681290.
    Citations: 1     Fields:    Translation:HumansCells
  23. Lipsett SC, Pollock NR, Branda JA, Gordon CD, Gordon CR, Lantos PM, Nigrovic LE. The Positive Predictive Value of Lyme Elisa for the Diagnosis of Lyme Disease in Children. Pediatr Infect Dis J. 2015 Nov; 34(11):1260-2. PMID: 26222064.
    Citations: 1     Fields:    Translation:Humans
  24. Song L, Zhao M, Duffy DC, Hansen J, Shields K, Wungjiranirun M, Chen X, Xu H, Leffler DA, Sambol SP, Gerding DN, Kelly CP, Pollock NR. Development and Validation of Digital Enzyme-Linked Immunosorbent Assays for Ultrasensitive Detection and Quantification of Clostridium difficile Toxins in Stool. J Clin Microbiol. 2015 Oct; 53(10):3204-12. PMID: 26202120.
    Citations: 9     Fields:    Translation:Humans
  25. Rodriguez NM, Linnes JC, Fan A, Ellenson CK, Pollock NR, Klapperich CM. Paper-Based RNA Extraction, in Situ Isothermal Amplification, and Lateral Flow Detection for Low-Cost, Rapid Diagnosis of Influenza A (H1N1) from Clinical Specimens. Anal Chem. 2015 Aug 04; 87(15):7872-9. PMID: 26125635.
    Citations: 11     Fields:    Translation:HumansCells
  26. Broadhurst MJ, Kelly JD, Miller A, Semper A, Bailey D, Groppelli E, Simpson A, Brooks T, Hula S, Nyoni W, Sankoh AB, Kanu S, Jalloh A, Ton Q, Sarchet N, George P, Perkins MD, Wonderly B, Murray M, Pollock NR. ReEBOV Antigen Rapid Test kit for point-of-care and laboratory-based testing for Ebola virus disease: a field validation study. Lancet. 2015 Aug 29; 386(9996):867-74. PMID: 26119838.
    Citations: 38     Fields:    Translation:HumansCells
  27. Jain S, Rajasingham R, Noubary F, Coonahan E, Schoeplein R, Baden R, Curry M, Afdhal N, Kumar S, Pollock NR. Performance of an Optimized Paper-Based Test for Rapid Visual Measurement of Alanine Aminotransferase (ALT) in Fingerstick and Venipuncture Samples. PLoS One. 2015; 10(5):e0128118. PMID: 26020244.
    Citations: 4     Fields:    Translation:HumansCTClinical Trials
  28. Pollock NR, Song L, Zhao M, Duffy DC, Chen X, Sambol SP, Gerding DN, Kelly CP. Differential immunodetection of toxin B from highly virulent Clostridium difficile BI/NAP-1/027. J Clin Microbiol. 2015 May; 53(5):1705-8. PMID: 25716449.
    Citations: 4     Fields:    Translation:HumansCells
  29. Denkinger CM, Kalantri Y, Schumacher SG, Michael JS, Shankar D, Saxena A, Sriram N, Balamugesh T, Luo R, Pollock NR, Pai M, Christopher DJ. Challenges in the development of an immunochromatographic interferon-gamma test for diagnosis of pleural tuberculosis. PLoS One. 2013; 8(12):e85447. PMID: 24376880.
    Citations: 1     Fields:    Translation:Humans
  30. Pollock NR, McAdam AJ, Pai M, Nardell EA, Bernardo J, Banaei N, Mobo J. Interferon ?-release assays for diagnosis of latent tuberculosis in healthcare workers in low-incidence settings: pros and cons. Clin Chem. 2014 May; 60(5):714-8. PMID: 24100806.
    Citations: 1     Fields:    Translation:HumansCells
  31. Pollock NR, McGray S, Colby DJ, Noubary F, Nguyen H, Nguyen TA, Khormaee S, Jain S, Hawkins K, Kumar S, Rolland JP, Beattie PD, Chau NV, Quang VM, Barfield C, Tietje K, Steele M, Weigl BH. Field evaluation of a prototype paper-based point-of-care fingerstick transaminase test. PLoS One. 2013; 8(9):e75616. PMID: 24098705.
    Citations: 10     Fields:    Translation:Humans
  32. Christopher DJ, Schumacher SG, Michael JS, Luo R, Balamugesh T, Duraikannan P, Pollock NR, Pai M, Denkinger CM. Performance of Xpert MTB/RIF on pleural tissue for the diagnosis of pleural tuberculosis. Eur Respir J. 2013 Nov; 42(5):1427-9. PMID: 23900990.
    Citations: 10     Fields:    Translation:Humans
  33. Pollock NR, Colby D, Rolland JP. A point-of-care paper-based fingerstick transaminase test: toward low-cost "lab-on-a-chip" technology for the developing world. Clin Gastroenterol Hepatol. 2013 May; 11(5):478-82. PMID: 23466712.
    Citations: 4     Fields:    Translation:Humans
  34. Zhang JY, Mahalanabis M, Liu L, Chang J, Pollock NR, Klapperich CM. A Disposable Microfluidic Virus Concentration Device Based on Evaporation and Interfacial Tension. Diagnostics (Basel). 2013 Mar; 3(1):155-69. PMID: 26617991.
    Citations: 3     
  35. Pollock NR, Macovei L, Kanunfre K, Dhiman R, Restrepo BI, Zarate I, Pino PA, Mora-Guzman F, Fujiwara RT, Michel G, Kashino SS, Campos-Neto A. Validation of Mycobacterium tuberculosis Rv1681 protein as a diagnostic marker of active pulmonary tuberculosis. J Clin Microbiol. 2013 May; 51(5):1367-73. PMID: 23390284.
    Citations: 10     Fields:    Translation:HumansCells
  36. Pollock NR, Colby D, Rolland JP. A point-of-care paper-based fingerstick transaminase test: toward low-cost "lab-on-a-chip" technology for the developing world. Clin Gastroenterol Hepatol. 2013; 5(11):478-82.
  37. Pollock NR, Macovei L, Kanunfre K, Dhiman R, Restrepo BI, Zarate I, Pino PA, Mora-Guzman F, Fujiwara RT, Michel G, Kashino SS, Campos-Neto A. Validation of Mycobacterium tuberculosis Rv1681 protein as a diagnostic marker of active pulmonary tuberculosis. J Clin Microbiol. 2013; 5(51):1367-73.
  38. Pollock NR, Rolland JP, Kumar S, Beattie PD, Jain S, Noubary F, Wong VL, Pohlmann RA, Ryan US, Whitesides GM. A paper-based multiplexed transaminase test for low-cost, point-of-care liver function testing. Sci Transl Med. 2012 Sep 19; 4(152):152ra129. PMID: 22993296.
    Citations: 44     Fields:    Translation:Humans
  39. Cao Q, Mahalanabis M, Chang J, Carey B, Hsieh C, Stanley A, Odell CA, Mitchell P, Feldman J, Pollock NR, Klapperich CM. Microfluidic chip for molecular amplification of influenza A RNA in human respiratory specimens. PLoS One. 2012; 7(3):e33176. PMID: 22457740.
    Citations: 13     Fields:    Translation:HumansCells
  40. Cao Q, Mahalanabis M, Chang J, Carey B, Hsieh C, Stanley A, Odell CA, Mitchell P, Feldman J, Pollock NR, Klapperich CM. Microfluidic chip for molecular amplification of influenza A RNA in human respiratory specimens. PLoS One. 2012; 3(7):e33176.
  41. Eisenberg RL, Pollock NR. Low yield of chest radiography in a large tuberculosis screening program. Radiology. 2010 Sep; 256(3):998-1004. PMID: 20720079.
    Citations: 8     Fields:    Translation:Humans
  42. Pollock NR, Duong S, Cheng A, Han LL, Smole S, Kirby JE. Ruling out novel H1N1 influenza virus infection with direct fluorescent antigen testing. Clin Infect Dis. 2009 Sep 15; 49(6):e66-8. PMID: 19681710.
    Citations: 19     Fields:    Translation:HumansCells
  43. Pollock NR, Kashino SS, Napolitano DR, Sloutsky A, Joshi S, Guillet J, Wong M, Nardell E, Campos-Neto A. Evaluation of the effect of treatment of latent tuberculosis infection on QuantiFERON-TB gold assay results. Infect Control Hosp Epidemiol. 2009 Apr; 30(4):392-5. PMID: 19236281.
    Citations: 7     Fields:    Translation:HumansCells
  44. Pollock NR, Campos-Neto A, Kashino S, Napolitano D, Behar SM, Shin D, Sloutsky A, Joshi S, Guillet J, Wong M, Nardell E. Discordant QuantiFERON-TB Gold test results among US healthcare workers with increased risk of latent tuberculosis infection: a problem or solution? Infect Control Hosp Epidemiol. 2008 Sep; 29(9):878-86. PMID: 18713053.
    Citations: 13     Fields:    Translation:HumansCells
  45. Pollock, Nira, M.D., Ph.D.; Kashino, Suely, Ph.D.; Campos-Neto, Antonio, M.D., Ph.D. . Development of a Novel Urine Antigen Detection Test for Active Tuberculosis. 43rd Joint Tuberculosis/Leprosy Conference and Diagnostics Workshop . 2008.
  46. Kashino SS, Pollock N, Napolitano DR, Rodrigues V, Campos-Neto A. Identification and characterization of Mycobacterium tuberculosis antigens in urine of patients with active pulmonary tuberculosis: an innovative and alternative approach of antigen discovery of useful microbial molecules. Clin Exp Immunol. 2008 Jul; 153(1):56-62. PMID: 18460016.
    Citations: 20     Fields:    Translation:HumansCells
  47. Napolitano DR, Pollock N, Kashino SS, Rodrigues V, Campos-Neto A. Identification of Mycobacterium tuberculosis ornithine carboamyltransferase in urine as a possible molecular marker of active pulmonary tuberculosis. Clin Vaccine Immunol. 2008 Apr; 15(4):638-43. PMID: 18305107.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  48. N. Pollock, A. Sloutsky, S. Joshi, M. Wong, and E. Nardell. Screening Health Care Workers (HCW) with Quantiferon-Gold: Possible False Negative Results in HCW with High Pre-Test Probability of Latent Tuberculosis Infection. Presented at the International Union Against Tuberculosis and Lung Disease (IUATLD) Conference and Global Symposium on Interferon-gamma Assays, Vancouver, Canada, February 2007. 2007.
  49. Pollock N, Westerling J, Sloutsky A. Specimen dilution increases the diagnostic utility of the gen-probe mycobacterium tuberculosis direct test. Am J Clin Pathol. 2006 Jul; 126(1):142-7. PMID: 16753601.
    Citations: 5     Fields:    Translation:Cells
  50. Pollock N, de Hostos EL, Turck CW, Vale RD. Reconstitution of membrane transport powered by a novel dimeric kinesin motor of the Unc104/KIF1A family purified from Dictyostelium. J Cell Biol. 1999 Nov 01; 147(3):493-506. PMID: 10545495.
    Citations: 14     Fields:    Translation:AnimalsCells
  51. Pollock N. Reconstitution of Microtubule-based Organelle Transport Using Factors Purified from Dictyostelium. 1999.
  52. Pollock N, Koonce MP, de Hostos EL, Vale RD. In vitro microtubule-based organelle transport in wild-type Dictyostelium and cells overexpressing a truncated dynein heavy chain. Cell Motil Cytoskeleton. 1998; 40(3):304-14. PMID: 9678672.
    Citations: 17     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.