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Simon Marc Helfgott, M.D.,C.M.

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Biography
2017
Distinguished Program Director Award

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sung YK, Yoshida K, Prince FHM, Frits ML, Cho SK, Choe JY, Lee HS, Lee J, Lee SS, Yoo DH, Helfgott SM, Shadick NA, Weinblatt ME, Solomon DH, Bae SC. Prevalence and predictors for sustained remission in rheumatoid arthritis. PLoS One. 2019; 14(4):e0214981. PMID: 31002669.
    Citations:    
  2. Fonseka CY, Rao DA, Teslovich NC, Korsunsky I, Hannes SK, Slowikowski K, Gurish MF, Donlin LT, Lederer JA, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Todd DJ, Bykerk VP, Karlson EW, Ermann J, Lee YC, Brenner MB, Raychaudhuri S. Mixed-effects association of single cells identifies an expanded effector CD4+ T cell subset in rheumatoid arthritis. Sci Transl Med. 2018 Oct 17; 10(463). PMID: 30333237.
    Citations:    Fields:    
  3. Tsui JL, Estrada OA, Deng Z, Wang KM, Law CS, Elicker BM, Jones KD, Dell SD, Gudmundsson G, Hansdottir S, Helfgott SM, Volpi S, Gattorno M, Waterfield MR, Chan AY, Chung SA, Ley B, Shum AK. Analysis of pulmonary features and treatment approaches in the COPA syndrome. ERJ Open Res. 2018 Apr; 4(2). PMID: 29977900.
    Citations:    
  4. Sparks JA, Iversen MD, Yu Z, Triedman NA, Prado MG, Miller Kroouze R, Kalia SS, Atkinson ML, Mody EA, Helfgott SM, Todd DJ, Dellaripa PF, Bermas BL, Costenbader KH, Deane KD, Lu B, Green RC, Karlson EW. Disclosure of Personalized Rheumatoid Arthritis Risk Using Genetics, Biomarkers, and Lifestyle Factors to Motivate Health Behavior Improvements: A Randomized Controlled Trial. Arthritis Care Res (Hoboken). 2018 Jun; 70(6):823-833. PMID: 29024454.
    Citations: 2     Fields:    
  5. Tedeschi SK, Stone RM, Helfgott SM. Calcium Pyrophosphate Crystal Inflammatory Arthritis (Pseudogout) with Myelodysplastic Syndrome: A New Paraneoplastic Syndrome? J Rheumatol. 2017 07; 44(7):1101-1102. PMID: 28668819.
    Citations:    Fields:    Translation:Humans
  6. Rao DA, Gurish MF, Marshall JL, Slowikowski K, Fonseka CY, Liu Y, Donlin LT, Henderson LA, Wei K, Mizoguchi F, Teslovich NC, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Lee YC, Todd DJ, Bykerk VP, Goodman SM, Pernis AB, Ivashkiv LB, Karlson EW, Nigrovic PA, Filer A, Buckley CD, Lederer JA, Raychaudhuri S, Brenner MB. Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis. Nature. 2017 02 01; 542(7639):110-114. PMID: 28150777.
    Citations: 38     Fields:    Translation:HumansCells
  7. Bhattacharyya S, Helfgott SM. Neurologic complications of systemic lupus erythematosus, sjögren syndrome, and rheumatoid arthritis. Semin Neurol. 2014 Sep; 34(4):425-36. PMID: 25369438.
    Citations: 4     Fields:    Translation:Humans
  8. Lichtman EI, Helfgott SM, Kriegel MA. Emerging therapies for systemic lupus erythematosus--focus on targeting interferon-alpha. Clin Immunol. 2012 Jun; 143(3):210-21. PMID: 22525889.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  9. Helfgott S. The research-based rheumatologist: strategies to remove the species from the endangered list. Arthritis Rheum. 2010 Dec; 62(12):3522-3. PMID: 20737469.
    Citations:    Fields:    Translation:Humans
  10. Lee YC, Chibnik LB, Lu B, Wasan AD, Edwards RR, Fossel AH, Helfgott SM, Solomon DH, Clauw DJ, Karlson EW. The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: a cross-sectional study. Arthritis Res Ther. 2009; 11(5):R160. PMID: 19874580.
    Citations: 42     Fields:    Translation:Humans
  11. Behar SM, Shin DS, Maier A, Coblyn J, Helfgott S, Weinblatt ME. Use of the T-SPOT.TB assay to detect latent tuberculosis infection among rheumatic disease patients on immunosuppressive therapy. J Rheumatol. 2009 Mar; 36(3):546-51. PMID: 19228655.
    Citations: 9     Fields:    Translation:Humans
  12. Schwarzberg AB, Alexander CB, DeAngelo DJ, Helfgott SM. Clinical problem-solving. A joint venture. N Engl J Med. 2008 Jun 05; 358(23):2496-501. PMID: 18525046.
    Citations:    Fields:    Translation:HumansCells
  13. Raychaudhuri S, Shmerling R, Ermann J, Helfgott S. Development of active tuberculosis following initiation of infliximab despite appropriate prophylaxis. Rheumatology (Oxford). 2007 May; 46(5):887-8. PMID: 17363399.
    Citations: 1     Fields:    Translation:Humans
  14. Todd DJ, Helfgott SM. Serum sickness following treatment with rituximab. J Rheumatol. 2007 Feb; 34(2):430-3. PMID: 17295433.
    Citations: 9     Fields:    Translation:Humans
  15. Johnsen AK, Schiff MH, Mease PJ, Moreland LW, Maier AL, Coblyn JS, Helfgott SM, Leff JA, Weinblatt ME. Comparison of 2 doses of etanercept (50 vs 100 mg) in active rheumatoid arthritis: a randomized double blind study. J Rheumatol. 2006 Apr; 33(4):659-64. PMID: 16482646.
    Citations: 11     Fields:    Translation:Humans
  16. Ang HT, Helfgott S. Do the clinical responses and complications following etanercept or infliximab therapy predict similar outcomes with the other tumor necrosis factor-alpha antagonists in patients with rheumatoid arthritis? J Rheumatol. 2003 Nov; 30(11):2315-8. PMID: 14677170.
    Citations: 13     Fields:    Translation:Humans
  17. Allsop SJ, Helfgott S. Whither the drug specialist? The work-force development needs of drug specialist staff and agencies. Drug Alcohol Rev. 2002 Sep; 21(3):215-22. PMID: 12270071.
    Citations:    Fields:    Translation:Humans
  18. Helfgott SM, Smith RN. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 21-2002. A 21-year-old man with arthritis during treatment for hyperthyroidism. N Engl J Med. 2002 Jul 11; 347(2):122-30. PMID: 12110741.
    Citations: 5     Fields:    Translation:Humans
  19. Coblyn JS, Shadick N, Helfgott S. Leflunomide-associated weight loss in rheumatoid arthritis. Arthritis Rheum. 2001 May; 44(5):1048-51. PMID: 11352235.
    Citations: 8     Fields:    Translation:HumansCells
  20. Helfgott SM. Sensible approach to low back pain. Bull Rheum Dis. 2001; 50(3):1-4. PMID: 12386944.
    Citations:    Fields:    Translation:Humans
  21. Solomon DH, Levin E, Helfgott SM. Patterns of medication use before and after bone densitometry: factors associated with appropriate treatment. J Rheumatol. 2000 Jun; 27(6):1496-500. PMID: 10852277.
    Citations: 11     Fields:    Translation:Humans
  22. Helfgott SM. Stiff-man syndrome: from the bedside to the bench. Arthritis Rheum. 1999 Jul; 42(7):1312-20. PMID: 10403257.
    Citations: 4     Fields:    Translation:Humans
  23. Weinblatt ME, Kremer JM, Coblyn JS, Maier AL, Helfgott SM, Morrell M, Byrne VM, Kaymakcian MV, Strand V. Pharmacokinetics, safety, and efficacy of combination treatment with methotrexate and leflunomide in patients with active rheumatoid arthritis. Arthritis Rheum. 1999 Jul; 42(7):1322-8. PMID: 10403258.
    Citations: 45     Fields:    Translation:HumansCTClinical Trials
  24. Helfgott SM. Unusual digital sparing in rheumatoid arthritis a case of neuropsychoimmunologic involvement. J Clin Rheumatol. 1997 Jun; 3(3):150-2. PMID: 19078174.
    Citations:    Fields:    
  25. Helfgott SM, Kieval RI. Polymyalgia rheumatica in patients with a normal erythrocyte sedimentation rate. Arthritis Rheum. 1996 Feb; 39(2):304-7. PMID: 8849384.
    Citations: 6     Fields:    Translation:Humans
  26. Gravallese EM, Winalski CS, Longtine J, Helfgott SM. Polyarthritis in a 78-year-old woman. Arthritis Rheum. 1994 Jul; 37(7):1087-95. PMID: 8024617.
    Citations:    Fields:    Translation:Humans
  27. Karlson EW, Sudarsky L, Ruderman E, Pierson S, Scott M, Helfgott SM. Treatment of stiff-man syndrome with intravenous immune globulin. Arthritis Rheum. 1994 Jun; 37(6):915-8. PMID: 8003064.
    Citations: 9     Fields:    Translation:Humans
  28. Helfgott SM. Nabumetone: a clinical appraisal. Semin Arthritis Rheum. 1994 Apr; 23(5):341-6. PMID: 8036523.
    Citations: 2     Fields:    Translation:Humans
  29. Helfgott SM, Picard DA, Cook JS. Herpes zoster radiculopathy. Spine (Phila Pa 1976). 1993 Dec; 18(16):2523-4. PMID: 8303458.
    Citations: 3     Fields:    Translation:Humans
  30. Helfgott SM, Karlson E, Beckman E. Misinterpretation of serum transaminase elevation in "occult" myositis. Am J Med. 1993 Oct; 95(4):447-9. PMID: 8213881.
    Citations: 3     Fields:    Translation:Humans
  31. Weinblatt ME, Kremer JM, Coblyn JS, Helfgott S, Maier AL, Petrillo G, Henson B, Rubin P, Sperling R. Zileuton, a 5-lipoxygenase inhibitor in rheumatoid arthritis. J Rheumatol. 1992 Oct; 19(10):1537-41. PMID: 1334515.
    Citations: 15     Fields:    Translation:HumansCTClinical Trials
  32. Helfgott SM, Skoff H. Scapholunate dissociation associated with crystal induced synovitis. J Rheumatol. 1992 Mar; 19(3):485-7. PMID: 1578468.
    Citations: 1     Fields:    Translation:HumansCells
  33. Weinblatt M, Helfgott S, Coblyn J, Spragg J, Uedelhoven WM, Tumeh S, Sperling R, Lorenz R, Maier A, Weber P. The effects of cyclosporin A on eicosanoid excretion in patients with rheumatoid arthritis. Arthritis Rheum. 1991 Apr; 34(4):481-5. PMID: 2012627.
    Citations: 1     Fields:    Translation:Humans
  34. Helfgott SM, Mosciscki RA, San Martin J, Lorenzo C, Kieval R, McKenna M, Nadol J, Trentham DE. Correlation between antibodies to type II collagen and treatment outcome in bilateral progressive sensorineural hearing loss. Lancet. 1991 Feb 16; 337(8738):387-9. PMID: 1671423.
    Citations: 6     Fields:    Translation:Humans
  35. Helfgott SM, Sandberg-Cook J, Zakim D, Nestler J. Diclofenac-associated hepatotoxicity. JAMA. 1990 Nov 28; 264(20):2660-2. PMID: 2232043.
    Citations: 13     Fields:    Translation:Humans
  36. Helfgott SM, Treseler PA. Cricoarytenoid synovitis in ankylosing spondylitis. Arthritis Rheum. 1990 Apr; 33(4):604-5. PMID: 2328038.
    Citations: 1     Fields:    Translation:Humans
  37. Helfgott SM. Total lymphoid irradiation. Rheum Dis Clin North Am. 1989 Aug; 15(3):577-82. PMID: 2672139.
    Citations:    Fields:    Translation:HumansAnimals
  38. Helfgott SM. Unusual features of iliopsoas bursitis. Arthritis Rheum. 1988 Oct; 31(10):1331-3. PMID: 3178913.
    Citations: 4     Fields:    Translation:Humans
  39. Helfgott SM, Lazarides G, Sandberg-Cook J. Cooccurrence of rheumatoid arthritis and ankylosing spondylitis. J Rheumatol. 1988 Sep; 15(9):1451-2. PMID: 3199405.
    Citations: 4     Fields:    Translation:Humans
  40. Caulfield JP, Hein A, Helfgott SM, Brahn E, Dynesius-Trentham RA, Trentham DE. Intraarticular injection of arthritogenic factor causes mast cell degranulation, inflammation, fat necrosis, and synovial hyperplasia. Lab Invest. 1988 Jul; 59(1):82-95. PMID: 3392961.
    Citations: 5     Fields:    Translation:AnimalsCells
  41. Helfgott SM, Kieval RI, Breedveld FC, Brahn E, Young CT, Dynesius-Trentham R, Trentham DE. Detection of arthritogenic factor in adjuvant arthritis. J Immunol. 1988 Mar 15; 140(6):1838-43. PMID: 3257989.
    Citations: 1     Fields:    Translation:AnimalsCells
  42. Helfgott SM, Bauer MR. Pedal gangrene caused by giant cell arteritis. Arthritis Rheum. 1987 Sep; 30(9):1078-9. PMID: 3663260.
    Citations: 3     Fields:    Translation:Humans
  43. Helfgott SM, Dynesius-Trentham R, Brahn E, Trentham DE. An arthritogenic lymphokine in the rat. J Exp Med. 1985 Nov 01; 162(5):1531-45. PMID: 3877139.
    Citations: 9     Fields:    Translation:AnimalsCells
  44. Helfgott SM, Bazin H, Dessein A, Trentham DE. Suppressive effects of anti-mu serum on the development of collagen arthritis in rats. Clin Immunol Immunopathol. 1984 Jun; 31(3):403-11. PMID: 6424991.
    Citations: 5     Fields:    Translation:AnimalsCells
  45. Brahn E, Helfgott SM, Belli JA, Anderson RJ, Reinherz EL, Schlossman SF, Austen KF, Trentham DE. Total lymphoid irradiation therapy in refractory rheumatoid arthritis. Fifteen- to forty-month followup. Arthritis Rheum. 1984 May; 27(5):481-8. PMID: 6609705.
    Citations: 5     Fields:    Translation:HumansCells
  46. Helfgott S, Rosenthall L, Esdaile J, Tannenbaum H. Generalized skeletal response to 99mtechnetium methylene diphosphonate in rheumatoid arthritis. J Rheumatol. 1982 Nov-Dec; 9(6):939-41. PMID: 6219221.
    Citations: 8     Fields:    Translation:Humans
  47. Helfgott S, Tannenbaum H, Rosenthall L. Radiophosphate imaging of regional migratory osteoporosis. Clin Nucl Med. 1979 Aug; 4(8):330-2. PMID: 466913.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.