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Vidal, Marc
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Marc Vidal, Ph.D.
Title
Professor of Genetics
Institution
Dana-Farber Cancer Institute
Department
Genetics
Address
Dana-Farber Cancer Institute
Smith Bldg 858
44 Binney St
Boston MA 02115
Phone
617/632-5180
Fax
617/632-5739
vCard
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research activities and funding
|
selected publications
|
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
UM1HG011989
(VIDAL, MARC)
Aug 23, 2021 - May 31, 2026
NIH
Molecular phenotyping of ~100,000 coding variants across Mendelian disease genes
Role: Principal Investigator
R01GM133185
(VIDAL, MARC)
Sep 10, 2019 - Aug 31, 2023
NIH
Incomplete Penetrance via Edgetic Suppression
Role: Principal Investigator
R01GM130885
(VIDAL, MARC)
Apr 20, 2019 - Feb 28, 2023
NIH
Interface-resolution domain-domain interactome map of the yeast complexome
Role: Principal Investigator
U01CA232161
(VIDAL, MARC)
Sep 17, 2018 - Aug 31, 2023
NIH
Rewiring of regulatory networks in breast cancer by transcription factor isoforms
Role: Principal Investigator
R01HG006061
(VIDAL, MARC)
Feb 17, 2011 - Nov 30, 2015
NIH
A S. cerevisiae high-coverage high-quality protein-protein binary interactome map
Role: Co-Principal Investigator
RC4HG006066
(VIDAL, MARC)
Sep 27, 2010 - Sep 30, 2013
NIH
Generation and validation of a comprehensive human disease mutant ORF resource
Role: Co-Principal Investigator
R33CA132073
(VIDAL, MARC)
Jun 5, 2008 - May 31, 2012
NIH
Application of Technologies for Interactome Network Analyses of Cancer Mutations
Role: Principal Investigator
R01ES015728
(VIDAL, MARC)
Sep 10, 2007 - Mar 31, 2012
NIH
Rewiring Pathways and Networks by Environmental Perturbations
Role: Principal Investigator
P50HG004233
(VIDAL, MARC)
Jun 20, 2007 - Aug 31, 2019
NIH
Genomic Analysis of Network Perturbations in Human Disease
Role: Principal Investigator
R13GM073377
(VIDAL, MARC)
Feb 1, 2005 - Jan 31, 2006
NIH
Conference on Systems &Biology
Role: Principal Investigator
R33CA105405
(VIDAL, MARC)
Apr 1, 2004 - Mar 31, 2008
NIH
Integrated interactome mapping
Role: Principal Investigator
R33CA097516
(VIDAL, MARC)
Sep 4, 2002 - Jul 31, 2007
NIH
A C. elegans localization-of-expression mapping project
Role: Principal Investigator
R21CA097516
(VIDAL, MARC)
Sep 4, 2002 - Jul 31, 2003
NIH
A C. elegans localization-of-expression mapping project
Role: Principal Investigator
R33CA081658
(VIDAL, MARC)
May 1, 1999 - Apr 30, 2003
NIH
NEW TECHNOLOGIES FOR PROTEIN INTERACTION MAPPING
Role: Principal Investigator
R21CA081658
(VIDAL, MARC)
May 1, 1999 - Feb 29, 2000
NIH
NEW TECHNOLOGIES FOR PROTEIN INTERACTION MAPPING
Role: Principal Investigator
P01CA080111
(WEINBERG, ROBERT A)
Mar 18, 1999 - Jan 31, 2019
NIH/NCI
Mechanisms of Breast Development and Carcinogenesis
Role: Co-Principal Investigator
U41HG001715
(VIDAL, MARC)
Jul 1, 1998 - Aug 31, 2019
NIH
A human binary interactome reference map by 2020
Role: Co-Principal Investigator
U01HG001715
(VIDAL, MARC)
Jul 1, 1998 - Sep 23, 2015
NIH
Mapping the first half of the REFERENCE human binary protein interactome
Role: Co-Principal Investigator
R01HG001715
(VIDAL, MARC)
Jul 1, 1998 - Jul 31, 2012
NIH
Mapping the Human Binary Interactome Network
Role: Co-Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Kim DK, Weller B, Lin CW, Sheykhkarimli D, Knapp JJ, Dugied G, Zanzoni A, Pons C, Tofaute MJ, Maseko SB, Spirohn K,
Laval F
, Lambourne L, Kishore N, Rayhan A, Sauer M, Young V, Halder H, la Rosa NM, Pogoutse O, Strobel A, Schwehn P, Li R, Rothballer ST, Altmann M, Cassonnet P, Coté AG, Vergara LE, Hazelwood I, Liu BB, Nguyen M, Pandiarajan R, Dohai B, Coloma PAR, Poirson J, Giuliana P, Willems L, Taipale M, Jacob Y, Hao T,
Hill DE
, Brun C, Twizere JC, Krappmann D, Heinig M, Falter C, Aloy P, Demeret C,
Vidal M
, Calderwood MA, Roth FP, Falter-Braun P. A proteome-scale map of the SARS-CoV-2-human contactome. Nat Biotechnol. 2023 01; 41(1):140-149.
PMID:
36217029
; PMCID:
PMC9849141
.
Citations:
4
Fields:
Bio
Biotechnology
Translation:
Humans
Cells
Kerselidou D, Dohai BS, Nelson DR, Daakour S, De Cock N, Hassoun ZAO, Kim DK, Olivet J, El Assal DC, Jaiswal A, Alzahmi A, Saha D, Pain C, Matthijssens F, Lemaitre P, Herfs M, Chapuis J, Ghesquiere B, Vertommen D, Kriechbaumer V, Knoops K, Lopez-Iglesias C, van Zandvoort M, Lambert JC, Hanson J, Desmet C, Thiry M, Lauersen KJ,
Vidal M
, Van Vlierberghe P, Dequiedt F, Salehi-Ashtiani K, Twizere JC. Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells. Sci Adv. 2021 05; 7(19).
PMID:
33962942
; PMCID:
PMC8104865
.
Citations:
3
Fields:
Sci
Science
Translation:
Animals
Cells
Cheng F, Zhao J, Wang Y, Lu W, Liu Z, Zhou Y, Martin WR,
Wang R
, Huang J, Hao T, Yue H, Ma J, Hou Y, Castrillon JA, Fang J, Lathia JD, Keri RA, Lightstone FC,
Antman EM
, Rabadan R,
Hill DE
, Eng C,
Vidal M
,
Loscalzo J
. Comprehensive characterization of protein-protein interactions perturbed by disease mutations. Nat Genet. 2021 03; 53(3):342-353.
PMID:
33558758
; PMCID:
PMC8237108
.
Citations:
38
Fields:
Gen
Genetics
Translation:
Humans
Ng AHM, Khoshakhlagh P, Rojo Arias JE, Pasquini G, Wang K, Swiersy A, Shipman SL,
Appleton E
, Kiaee K, Kohman RE, Vernet A, Dysart M, Leeper K, Saylor W, Huang JY, Graveline A, Taipale J,
Hill DE
,
Vidal M
,
Melero-Martin JM
, Busskamp V, Church GM. A comprehensive library of human transcription factors for cell fate engineering. Nat Biotechnol. 2021 04; 39(4):510-519.
PMID:
33257861
; PMCID:
PMC7610615
.
Citations:
37
Fields:
Bio
Biotechnology
Translation:
Humans
Cells
Kim JH, Seo Y, Jo M, Jeon H, Kim YS, Kim EJ, Seo D, Lee WH, Kim SR, Yachie N, Zhong Q,
Vidal M
, Roth FP, Suk K. Interrogation of kinase genetic interactions provides a global view of PAK1-mediated signal transduction pathways. J Biol Chem. 2020 12 11; 295(50):16906-16919.
PMID:
33060198
; PMCID:
PMC7863907
.
Citations:
1
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Wierbowski SD, Vo TV, Falter-Braun P, Jobe TO, Kruse LH, Wei X, Liang J, Meyer MJ, Akturk N, Rivera-Erick CA, Cordero NA, Paramo MI, Shayhidin EE, Bertolotti M, Tippens ND, Akther K, Sharma R, Katayose Y, Salehi-Ashtiani K, Hao T, Ronald PC, Ecker JR, Schweitzer PA, Kikuchi S, Mizuno H,
Hill DE
,
Vidal M
, Moghe GD, McCouch SR, Yu H. A massively parallel barcoded sequencing pipeline enables generation of the first ORFeome and interactome map for rice. Proc Natl Acad Sci U S A. 2020 05 26; 117(21):11836-11842.
PMID:
32398372
.
Citations:
8
Fields:
Sci
Science
Translation:
Animals
Sheynkman GM, Tuttle KS,
Laval F
, Tseng E, Underwood JG, Yu L, Dong D, Smith ML, Sebra R, Willems L, Hao T, Calderwood MA,
Hill DE
,
Vidal M
. ORF Capture-Seq as a versatile method for targeted identification of full-length isoforms. Nat Commun. 2020 05 11; 11(1):2326.
PMID:
32393825
.
Citations:
9
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Kim JH, Seo Y, Jo M, Jeon H, Lee WH, Yachie N, Zhong Q,
Vidal M
, Roth FP, Suk K. Yeast-Based Genetic Interaction Analysis of Human Kinome. Cells. 2020 05 07; 9(5).
PMID:
32392905
; PMCID:
PMC7291280
.
Citations:
4
Fields:
Bio
Biophysics
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Luck K, Kim DK,
Lambourne L
, Spirohn K, Begg BE, Bian W, Brignall R, Cafarelli T, Campos-Laborie FJ, Charloteaux B, Choi D, Coté AG, Daley M, Deimling S, Desbuleux A, Dricot A, Gebbia M, Hardy MF, Kishore N, Knapp JJ, Kovács IA, Lemmens I, Mee MW, Mellor JC, Pollis C, Pons C, Richardson AD, Schlabach S, Teeking B, Yadav A, Babor M, Balcha D, Basha O, Bowman-Colin C, Chin SF, Choi SG, Colabella C, Coppin G, D'Amata C, De Ridder D, De Rouck S, Duran-Frigola M, Ennajdaoui H, Goebels F, Goehring L, Gopal A, Haddad G,
Hatchi E
, Helmy M, Jacob Y, Kassa Y, Landini S, Li R, van Lieshout N, MacWilliams A, Markey D, Paulson JN, Rangarajan S, Rasla J, Rayhan A, Rolland T, San-Miguel A, Shen Y, Sheykhkarimli D, Sheynkman GM, Simonovsky E, Tasan M, Tejeda A, Tropepe V, Twizere JC, Wang Y, Weatheritt RJ, Weile J, Xia Y, Yang X, Yeger-Lotem E, Zhong Q, Aloy P, Bader GD, De Las Rivas J, Gaudet S, Hao T, Rak J, Tavernier J,
Hill DE
,
Vidal M
, Roth FP, Calderwood MA. A reference map of the human binary protein interactome. Nature. 2020 04; 580(7803):402-408.
PMID:
32296183
.
Citations:
267
Fields:
Sci
Science
Translation:
Humans
Cells
Yadav A,
Vidal M
, Luck K. Precision medicine - networks to the rescue. Curr Opin Biotechnol. 2020 06; 63:177-189.
PMID:
32199228
.
Citations:
10
Fields:
Bio
Biotechnology
Translation:
Humans
Sun S, Weile J, Verby M, Wu Y, Wang Y, Cote AG, Fotiadou I, Kitaygorodsky J,
Vidal M
, Rine J, Ješina P, Kožich V, Roth FP. A proactive genotype-to-patient-phenotype map for cystathionine beta-synthase. Genome Med. 2020 01 30; 12(1):13.
PMID:
32000841
.
Citations:
14
Fields:
Gen
Genetics
Translation:
Humans
Animals
Choi SG, Olivet J, Cassonnet P, Vidalain PO, Luck K,
Lambourne L
, Spirohn K, Lemmens I, Dos Santos M, Demeret C, Jones L, Rangarajan S, Bian W, Coutant EP, Janin YL, van der Werf S, Trepte P, Wanker EE, De Las Rivas J, Tavernier J, Twizere JC, Hao T,
Hill DE
,
Vidal M
, Calderwood MA, Jacob Y. Maximizing binary interactome mapping with a minimal number of assays. Nat Commun. 2019 08 29; 10(1):3907.
PMID:
31467278
.
Citations:
19
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Cheng F, Lu W, Liu C, Fang J, Hou Y,
Handy DE
,
Wang R
, Zhao Y, Yang Y, Huang J,
Hill DE
,
Vidal M
, Eng C,
Loscalzo J
. A genome-wide positioning systems network algorithm for in silico drug repurposing. Nat Commun. 2019 08 02; 10(1):3476.
PMID:
31375661
.
Citations:
73
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Lee EJ, Kim N, Park JW, Kang KH, Kim WI, Sim NS, Jeong CS, Blackshaw S,
Vidal M
, Huh SO, Kim D, Lee JH, Kim JW. Global Analysis of Intercellular Homeodomain Protein Transfer. Cell Rep. 2019 07 16; 28(3):712-722.e3.
PMID:
31315049
; PMCID:
PMC9472292
.
Citations:
10
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Kovács IA, Luck K, Spirohn K, Wang Y, Pollis C, Schlabach S, Bian W, Kim DK, Kishore N, Hao T, Calderwood MA,
Vidal M
, Barabási AL. Network-based prediction of protein interactions. Nat Commun. 2019 03 18; 10(1):1240.
PMID:
30886144
.
Citations:
60
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Alonso-López D, Campos-Laborie FJ, Gutiérrez MA,
Lambourne L
, Calderwood MA,
Vidal M
, De Las Rivas J. APID database: redefining protein-protein interaction experimental evidences and binary interactomes. Database (Oxford). 2019 01 01; 2019.
PMID:
30715274
; PMCID:
PMC6354026
.
Citations:
43
Fields:
Com
Computational Biology
Translation:
Humans
Animals
Sharma A,
Halu A
,
Decano JL
, Padi M, Liu YY, Prasad RB, Fadista J, Santolini M, Menche J,
Weiss ST
,
Vidal M
,
Silverman EK
,
Aikawa M
, Barabási AL, Groop L,
Loscalzo J
. Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes. NPJ Syst Biol Appl. 2018; 4:25.
PMID:
29977601
.
Citations:
10
Fields:
Com
Computational Biology
Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, Ivanov AR, Jensen ON, Jewett MC, Kelleher NL, Kiessling LL, Krogan NJ, Larsen MR, Loo JA, Ogorzalek Loo RR, Lundberg E, MacCoss MJ, Mallick P,
Mootha VK
, Mrksich M, Muir TW, Patrie SM, Pesavento JJ, Pitteri SJ, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff SA, Smith LM, Snyder MP, Thomas PM, Uhlén M, Van Eyk JE,
Vidal M
,
Walt DR
, White FM, Williams ER, Wohlschlager T, Wysocki VH, Yates NA, Young NL, Zhang B. How many human proteoforms are there? Nat Chem Biol. 2018 02 14; 14(3):206-214.
PMID:
29443976
; PMCID:
PMC5837046
.
Citations:
215
Fields:
Bio
Biology
Che
Chemistry
Translation:
Humans
Cells
Martínez-Noël G, Luck K, Kühnle S,
Desbuleux A
,
Szajner P
, Galligan JT, Rodriguez D, Zheng L, Boyland K, Leclere F, Zhong Q,
Hill DE
,
Vidal M
,
Howley PM
. Network Analysis of UBE3A/E6AP-Associated Proteins Provides Connections to Several Distinct Cellular Processes. J Mol Biol. 2018 03 30; 430(7):1024-1050.
PMID:
29426014
; PMCID:
PMC5866790
.
Citations:
16
Fields:
Mol
Molecular Biology
Translation:
Humans
Cells
Choi SG, Richardson A,
Lambourne L
,
Hill DE
,
Vidal M
. Protein Interactomics by Two-Hybrid Methods. Methods Mol Biol. 2018; 1794:1-14.
PMID:
29855947
; PMCID:
PMC6948107
.
Citations:
3
Fields:
Mol
Molecular Biology
Translation:
Humans
Weile J, Sun S, Cote AG, Knapp J, Verby M, Mellor JC, Wu Y, Pons C, Wong C, van Lieshout N, Yang F, Tasan M, Tan G, Yang S, Fowler DM, Nussbaum R, Bloom JD,
Vidal M
,
Hill DE
, Aloy P, Roth FP. A framework for exhaustively mapping functional missense variants. Mol Syst Biol. 2017 12 21; 13(12):957.
PMID:
29269382
.
Citations:
57
Fields:
Com
Computational Biology
Mol
Molecular Biology
Translation:
Humans
Carter AC
, Chang HY, Church G, Dombkowski A, Ecker JR, Gil E, Giresi PG, Greely H, Greenleaf WJ,
Hacohen N
, He C,
Hill D
, Ko J,
Kohane I
, Kundaje A, Palmer M, Snyder MP, Tung J, Urban A,
Vidal M
, Wong W. Challenges and recommendations for epigenomics in precision health. Nat Biotechnol. 2017 12 08; 35(12):1128-1132.
PMID:
29220033
; PMCID:
PMC5821229
.
Citations:
12
Fields:
Bio
Biotechnology
Translation:
Humans
Ghadie MA,
Lambourne L
,
Vidal M
, Xia Y. Domain-based prediction of the human isoform interactome provides insights into the functional impact of alternative splicing. PLoS Comput Biol. 2017 Aug; 13(8):e1005717.
PMID:
28846689
.
Citations:
15
Fields:
Com
Computational Biology
Translation:
Humans
Cells
Jo M, Chung AY, Yachie N, Seo M, Jeon H, Nam Y, Seo Y, Kim E, Zhong Q,
Vidal M
, Park HC, Roth FP, Suk K. Yeast genetic interaction screen of human genes associated with amyotrophic lateral sclerosis: identification of MAP2K5 kinase as a potential drug target. Genome Res. 2017 09; 27(9):1487-1500.
PMID:
28596290
; PMCID:
PMC5580709
.
Citations:
9
Fields:
Gen
Genetics
Translation:
Humans
Animals
Yao C, Joehanes R, Johnson AD, Huan T, Liu C, Freedman JE, Munson PJ,
Hill DE
,
Vidal M
, Levy D. Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits. Am J Hum Genet. 2017 06 01; 100(6):985-986.
PMID:
28575653
; PMCID:
PMC5883609
.
Citations:
9
Fields:
Gen
Genetics
Yang F, Sun S, Tan G, Costanzo M,
Hill DE
,
Vidal M
, Andrews BJ, Boone C, Roth FP. Identifying pathogenicity of human variants via paralog-based yeast complementation. PLoS Genet. 2017 May; 13(5):e1006779.
PMID:
28542158
; PMCID:
PMC5466341
.
Citations:
16
Fields:
Gen
Genetics
Translation:
Humans
Animals
Yao C, Joehanes R, Johnson AD, Huan T, Liu C, Freedman JE, Munson PJ,
Hill DE
,
Vidal M
, Levy D. Dynamic Role of trans Regulation of Gene Expression in Relation to Complex Traits. Am J Hum Genet. 2017 Apr 06; 100(4):571-580.
PMID:
28285768
; PMCID:
PMC5384035
.
Citations:
38
Fields:
Gen
Genetics
Translation:
Humans
Luck K, Sheynkman GM, Zhang I,
Vidal M
. Proteome-Scale Human Interactomics. Trends Biochem Sci. 2017 05; 42(5):342-354.
PMID:
28284537
; PMCID:
PMC5409865
.
Citations:
55
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Karras GI, Yi S, Sahni N, Fischer M, Xie J,
Vidal M
,
D'Andrea AD
, Whitesell L, Lindquist S. HSP90 Shapes the Consequences of Human Genetic Variation. Cell. 2017 Feb 23; 168(5):856-866.e12.
PMID:
28215707
.
Citations:
46
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Chung CY,
Khurana V
, Yi S, Sahni N, Loh KH, Auluck PK, Baru V, Udeshi ND, Freyzon Y, Carr SA,
Hill DE
,
Vidal M
, Ting AY, Lindquist S. In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons. Cell Syst. 2017 02 22; 4(2):242-250.e4.
PMID:
28131823
.
Citations:
46
Fields:
Cel
Cell Biology
Com
Computational Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Khurana V
, Peng J, Chung CY, Auluck PK,
Fanning S
, Tardiff DF, Bartels T, Koeva M, Eichhorn SW, Benyamini H, Lou Y, Nutter-Upham A, Baru V, Freyzon Y, Tuncbag N, Costanzo M, San Luis BJ, Schöndorf DC, Barrasa MI, Ehsani S, Sanjana N, Zhong Q, Gasser T, Bartel DP,
Vidal M
, Deleidi M, Boone C, Fraenkel E, Berger B, Lindquist S. Genome-Scale Networks Link Neurodegenerative Disease Genes to a-Synuclein through Specific Molecular Pathways. Cell Syst. 2017 02 22; 4(2):157-170.e14.
PMID:
28131822
.
Citations:
55
Fields:
Cel
Cell Biology
Com
Computational Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Lievens S, Van der Heyden J, Masschaele D, De Ceuninck L, Petta I, Gupta S, De Puysseleyr V, Vauthier V, Lemmens I, De Clercq DJ, Defever D, Vanderroost N, De Smet AS, Eyckerman S, Van Calenbergh S, Martens L, De Bosscher K, Libert C,
Hill DE
,
Vidal M
, Tavernier J. Proteome-scale Binary Interactomics in Human Cells. Mol Cell Proteomics. 2016 Dec; 15(12):3624-3639.
PMID:
27803151
; PMCID:
PMC5141276
.
Citations:
9
Fields:
Bio
Biochemistry
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Vidal M
. Playing Hide-and-Seek with Yeast. Cell. 2016 Aug 25; 166(5):1069-1073.
PMID:
27565335
.
Citations:
Fields:
Cel
Cell Biology
Translation:
Animals
Yazaki J, Galli M, Kim AY, Nito K, Aleman F, Chang KN, Carvunis AR, Quan R, Nguyen H, Song L, Alvarez JM, Huang SS, Chen H, Ramachandran N, Altmann S, Gutiérrez RA,
Hill DE
, Schroeder JI, Chory J, LaBaer J,
Vidal M
, Braun P, Ecker JR. Mapping transcription factor interactome networks using HaloTag protein arrays. Proc Natl Acad Sci U S A. 2016 07 19; 113(29):E4238-47.
PMID:
27357687
; PMCID:
PMC4961138
.
Citations:
25
Fields:
Sci
Science
Translation:
Animals
Rambout X, Detiffe C, Bruyr J, Mariavelle E, Cherkaoui M, Brohée S, Demoitié P, Lebrun M, Soin R, Lesage B, Guedri K, Beullens M, Bollen M, Farazi TA, Kettmann R, Struman I,
Hill DE
,
Vidal M
, Kruys V, Simonis N, Twizere JC, Dequiedt F. The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression. Nat Struct Mol Biol. 2016 07; 23(7):663-72.
PMID:
27273514
.
Citations:
21
Fields:
Mol
Molecular Biology
Translation:
Humans
Cells
Vidal M
. How much of the human protein interactome remains to be mapped? Sci Signal. 2016 05 10; 9(427):eg7.
PMID:
27165778
.
Citations:
4
Fields:
Cel
Cell Biology
Phy
Physiology
Sci
Science
Translation:
Humans
Animals
Cells
Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, Yi S, Tyagi T, Sheykhkarimli D, Roth JF, Wong C, Musa L, Snider J, Liu YC, Yu H, Braun P, Stagljar I, Hao T, Calderwood MA, Pelletier L, Aloy P,
Hill DE
,
Vidal M
, Roth FP. Pooled-matrix protein interaction screens using Barcode Fusion Genetics. Mol Syst Biol. 2016 Apr 22; 12(4):863.
PMID:
27107012
.
Citations:
55
Fields:
Com
Computational Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Tasan M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barabási AL,
Hill DE
, Aloy P, Cusick ME, Xia Y, Roth FP,
Vidal M
. An inter-species protein-protein interaction network across vast evolutionary distance. Mol Syst Biol. 2016 Apr 22; 12(4):865.
PMID:
27107014
.
Citations:
18
Fields:
Com
Computational Biology
Mol
Molecular Biology
Translation:
Humans
Barrera LA, Vedenko A, Kurland JV,
Rogers JM
, Gisselbrecht SS,
Rossin EJ
, Woodard J,
Mariani L
, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M,
Daly MJ
,
Vidal M
,
Hill DE
,
Bulyk ML
. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science. 2016 Mar 25; 351(6280):1450-1454.
PMID:
27013732
.
Citations:
66
Fields:
Sci
Science
Translation:
Humans
Cells
Sun S, Yang F, Tan G, Costanzo M, Oughtred R, Hirschman J, Theesfeld CL, Bansal P, Sahni N, Yi S, Yu A, Tyagi T, Tie C,
Hill DE
,
Vidal M
, Andrews BJ, Boone C, Dolinski K, Roth FP. An extended set of yeast-based functional assays accurately identifies human disease mutations. Genome Res. 2016 05; 26(5):670-80.
PMID:
26975778
; PMCID:
PMC4864455
.
Citations:
55
Fields:
Gen
Genetics
Translation:
Humans
Animals
Cells
Chiu CN, Rihel J, Lee DA, Singh C, Mosser EA, Chen S, Sapin V, Pham U, Engle J, Niles BJ, Montz CJ, Chakravarthy S, Zimmerman S, Salehi-Ashtiani K,
Vidal M
, Schier AF, Prober DA. A Zebrafish Genetic Screen Identifies Neuromedin U as a Regulator of Sleep/Wake States. Neuron. 2016 Feb 17; 89(4):842-56.
PMID:
26889812
.
Citations:
45
Fields:
Neu
Neurology
Translation:
Humans
Animals
Cells
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Wanamaker SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B,
Chen AA
, Calderwood MA, Aloy P, Roth FP,
Hill DE
, Iakoucheva LM, Xia Y,
Vidal M
. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell. 2016 02 11; 164(4):805-17.
PMID:
26871637
; PMCID:
PMC4882190
.
Citations:
225
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Guney E, Menche J,
Vidal M
, Barábasi AL. Network-based in silico drug efficacy screening. Nat Commun. 2016 Feb 01; 7:10331.
PMID:
26831545
.
Citations:
182
Fields:
Bio
Biology
Sci
Science
Translation:
Cells
Neupane M, Clark AP, Landini S, Birkbak NJ, Eklund AC, Lim E, Culhane AC, Barry WT, Schumacher SE,
Beroukhim R
,
Szallasi Z
,
Vidal M
,
Hill DE
, Silver DP. MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy. Cancer Discov. 2016 Jan; 6(1):45-58.
PMID:
26546296
.
Citations:
28
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Wang Y, Sahni N,
Vidal M
. Global Edgetic Rewiring in Cancer Networks. Cell Syst. 2015 Oct 28; 1(4):251-3.
PMID:
27136053
.
Citations:
5
Fields:
Cel
Cell Biology
Com
Computational Biology
Mol
Molecular Biology
Fuxman Bass JI, Sahni N, Shrestha S, Garcia-Gonzalez A, Mori A, Bhat N, Yi S,
Hill DE
,
Vidal M
, Walhout AJM. Human gene-centered transcription factor networks for enhancers and disease variants. Cell. 2015 Apr 23; 161(3):661-673.
PMID:
25910213
.
Citations:
58
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G,
Khurana V
, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova AK, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ,
Sunyaev S
, Berger B, Barabási AL, Charloteaux B,
Hill DE
, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S,
Vidal M
. Widespread macromolecular interaction perturbations in human genetic disorders. Cell. 2015 Apr 23; 161(3):647-660.
PMID:
25910212
.
Citations:
222
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Yang F, Petsalaki E, Rolland T,
Hill DE
,
Vidal M
, Roth FP. Protein domain-level landscape of cancer-type-specific somatic mutations. PLoS Comput Biol. 2015 Mar; 11(3):e1004147.
PMID:
25794154
.
Citations:
33
Fields:
Com
Computational Biology
Translation:
Humans
Cells
Menche J, Sharma A, Kitsak M, Ghiassian SD,
Vidal M
,
Loscalzo J
, Barabási AL. Disease networks. Uncovering disease-disease relationships through the incomplete interactome. Science. 2015 Feb 20; 347(6224):1257601.
PMID:
25700523
.
Citations:
535
Fields:
Sci
Science
Translation:
Humans
Sharma A, Menche J, Huang CC, Ort T,
Zhou X
, Kitsak M, Sahni N, Thibault D, Voung L, Guo F, Ghiassian SD, Gulbahce N, Baribaud F, Tocker J, Dobrin R, Barnathan E, Liu H, Panettieri RA, Tantisira KG, Qiu W,
Raby BA
,
Silverman EK
,
Vidal M
,
Weiss ST
, Barabási AL. A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma. Hum Mol Genet. 2015 Jun 01; 24(11):3005-20.
PMID:
25586491
; PMCID:
PMC4447811
.
Citations:
81
Fields:
Gen
Genetics
Mol
Molecular Biology
Translation:
Humans
Cells
Tasan M, Musso G, Hao T,
Vidal M
,
MacRae CA
, Roth FP. Selecting causal genes from genome-wide association studies via functionally coherent subnetworks. Nat Methods. 2015 Feb; 12(2):154-9.
PMID:
25532137
; PMCID:
PMC4480866
.
Citations:
38
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Humans
Animals
Vidal M
, Fields S. The yeast two-hybrid assay: still finding connections after 25 years. Nat Methods. 2014 Dec; 11(12):1203-6.
PMID:
25584376
.
Citations:
28
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Humans
Animals
Rolland T, Tasan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, Yi S, Lemmens I, Fontanillo C, Mosca R, Kamburov A, Ghiassian SD, Yang X, Ghamsari L, Balcha D, Begg BE, Braun P, Brehme M, Broly MP, Carvunis AR, Convery-Zupan D, Corominas R, Coulombe-Huntington J, Dann E, Dreze M, Dricot A, Fan C,
Franzosa E
, Gebreab F, Gutierrez BJ, Hardy MF, Jin M, Kang S, Kiros R, Lin GN, Luck K, MacWilliams A, Menche J, Murray RR, Palagi A, Poulin MM, Rambout X, Rasla J, Reichert P, Romero V, Ruyssinck E, Sahalie JM, Scholz A, Shah AA, Sharma A, Shen Y, Spirohn K, Tam S, Tejeda AO, Wanamaker SA, Twizere JC, Vega K, Walsh J, Cusick ME, Xia Y, Barabási AL, Iakoucheva LM, Aloy P, De Las Rivas J, Tavernier J, Calderwood MA,
Hill DE
, Hao T, Roth FP,
Vidal M
. A proteome-scale map of the human interactome network. Cell. 2014 11 20; 159(5):1212-1226.
PMID:
25416956
; PMCID:
PMC4266588
.
Citations:
586
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Brehme M, Voisine C, Rolland T, Wachi S, Soper JH, Zhu Y, Orton K, Villella A, Garza D,
Vidal M
, Ge H, Morimoto RI. A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease. Cell Rep. 2014 Nov 06; 9(3):1135-50.
PMID:
25437566
.
Citations:
223
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Gu L, Li C, Aach J,
Hill DE
,
Vidal M
,
Church GM
. Multiplex single-molecule interaction profiling of DNA-barcoded proteins. Nature. 2014 Nov 27; 515(7528):554-7.
PMID:
25252978
.
Citations:
36
Fields:
Sci
Science
Translation:
Cells
Weßling R, Epple P, Altmann S, He Y, Yang L, Henz SR, McDonald N, Wiley K, Bader KC, Gläßer C, Mukhtar MS, Haigis S, Ghamsari L, Stephens AE, Ecker JR,
Vidal M
, Jones JD, Mayer KF, Ver Loren van Themaat E, Weigel D, Schulze-Lefert P, Dangl JL, Panstruga R, Braun P. Convergent targeting of a common host protein-network by pathogen effectors from three kingdoms of life. Cell Host Microbe. 2014 Sep 10; 16(3):364-75.
PMID:
25211078
; PMCID:
PMC4191710
.
Citations:
141
Fields:
Mic
Microbiology
Translation:
Animals
Cells
Hill SJ
, Rolland T,
Adelmant G
, Xia X, Owen MS, Dricot A, Zack TI, Sahni N, Jacob Y, Hao T, McKinney KM, Clark AP, Reyon D, Tsai SQ,
Joung JK
,
Beroukhim R
,
Marto JA
,
Vidal M
, Gaudet S,
Hill DE
, Livingston DM. Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage. Genes Dev. 2014 Sep 01; 28(17):1957-75.
PMID:
25184681
.
Citations:
59
Fields:
Mol
Molecular Biology
Translation:
Humans
Cells
Corominas R, Yang X, Lin GN, Kang S, Shen Y, Ghamsari L, Broly M, Rodriguez M, Tam S, Trigg SA, Fan C, Yi S, Tasan M, Lemmens I, Kuang X, Zhao N, Malhotra D, Michaelson JJ, Vacic V, Calderwood MA, Roth FP, Tavernier J, Horvath S, Salehi-Ashtiani K, Korkin D, Sebat J,
Hill DE
, Hao T,
Vidal M
, Iakoucheva LM. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism. Nat Commun. 2014 Apr 11; 5:3650.
PMID:
24722188
; PMCID:
PMC3996537
.
Citations:
68
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Dittmer TA, Sahni N, Kubben N,
Hill DE
,
Vidal M
, Burgess RC, Roukos V, Misteli T. Systematic identification of pathological lamin A interactors. Mol Biol Cell. 2014 May; 25(9):1493-510.
PMID:
24623722
.
Citations:
39
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Sahni N, Yi S, Zhong Q, Jailkhani N, Charloteaux B, Cusick ME,
Vidal M
. Edgotype: a fundamental link between genotype and phenotype. Curr Opin Genet Dev. 2013 Dec; 23(6):649-57.
PMID:
24287335
.
Citations:
69
Fields:
Gen
Genetics
Translation:
Humans
Cells
Mehra A, Zahra A, Thompson V, Sirisaengtaksin N, Wells A, Porto M, Köster S, Penberthy K, Kubota Y, Dricot A, Rogan D,
Vidal M
,
Hill DE
, Bean AJ, Philips JA. Mycobacterium tuberculosis type VII secreted effector EsxH targets host ESCRT to impair trafficking. PLoS Pathog. 2013 Oct; 9(10):e1003734.
PMID:
24204276
.
Citations:
83
Fields:
Mic
Microbiology
Translation:
Humans
Animals
Cells
Lambert JP, Ivosev G, Couzens AL, Larsen B, Taipale M, Lin ZY, Zhong Q, Lindquist S,
Vidal M
, Aebersold R, Pawson T, Bonner R, Tate S, Gingras AC. Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition. Nat Methods. 2013 Dec; 10(12):1239-45.
PMID:
24162924
; PMCID:
PMC3882083
.
Citations:
122
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Humans
Xin X, Gfeller D, Cheng J, Tonikian R, Sun L, Guo A, Lopez L, Pavlenco A, Akintobi A, Zhang Y, Rual JF, Currell B, Seshagiri S, Hao T, Yang X, Shen YA, Salehi-Ashtiani K, Li J, Cheng AT, Bouamalay D, Lugari A,
Hill DE
, Grimes ML, Drubin DG, Grant BD,
Vidal M
, Boone C, Sidhu SS, Bader GD. SH3 interactome conserves general function over specific form. Mol Syst Biol. 2013; 9:652.
PMID:
23549480
; PMCID:
PMC3658277
.
Citations:
34
Fields:
Com
Computational Biology
Mol
Molecular Biology
Translation:
Animals
Cells
Lambert B, Vandeputte J, Remacle S, Bergiers I, Simonis N, Twizere JC,
Vidal M
, Rezsohazy R. Protein interactions of the transcription factor Hoxa1. BMC Dev Biol. 2012 Oct 22; 12:29.
PMID:
23088713
.
Citations:
20
Fields:
Emb
Embryology
Translation:
Humans
Animals
Cells
Fine DA, Rozenblatt-Rosen O, Padi M, Korkhin A, James RL,
Adelmant G
, Yoon R, Guo L, Berrios C, Zhang Y, Calderwood MA, Velmurgan S, Cheng J,
Marto JA
,
Hill DE
, Cusick ME,
Vidal M
, Florens L, Washburn MP, Litovchick L,
DeCaprio JA
. Identification of FAM111A as an SV40 host range restriction and adenovirus helper factor. PLoS Pathog. 2012; 8(10):e1002949.
PMID:
23093934
.
Citations:
33
Fields:
Mic
Microbiology
Translation:
Humans
Animals
Cells
Neveu G, Cassonnet P, Vidalain PO, Rolloy C, Mendoza J, Jones L, Tangy F, Muller M, Demeret C, Tafforeau L, Lotteau V, Rabourdin-Combe C, Travé G, Dricot A,
Hill DE
,
Vidal M
, Favre M, Jacob Y. Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase. Methods. 2012 Dec; 58(4):349-59.
PMID:
22898364
.
Citations:
27
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Rozenblatt-Rosen O,
Deo RC
, Padi M,
Adelmant G
, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR,
Chen AA
, Cheng J, Correll M, Duarte M, Fan C, Feltkamp MC,
Ficarro SB
, Franchi R, Garg BK, Gulbahce N, Hao T, Holthaus AM, James R, Korkhin A, Litovchick L, Mar JC,
Pak TR
, Rabello S, Rubio R, Shen Y, Singh S, Spangle JM, Tasan M, Wanamaker S, Webber JT, Roecklein-Canfield J, Johannsen E, Barabási AL,
Beroukhim R
,
Kieff E
, Cusick ME,
Hill DE
, Münger K,
Marto JA
,
Quackenbush J
, Roth FP,
DeCaprio JA
,
Vidal M
. Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins. Nature. 2012 Jul 26; 487(7408):491-5.
PMID:
22810586
.
Citations:
227
Fields:
Sci
Science
Translation:
Humans
Cells
Carvunis AR, Rolland T, Wapinski I, Calderwood MA, Yildirim MA, Simonis N, Charloteaux B, Hidalgo CA, Barbette J, Santhanam B, Brar GA, Weissman JS, Regev A, Thierry-Mieg N, Cusick ME,
Vidal M
. Proto-genes and de novo gene birth. Nature. 2012 Jul 19; 487(7407):370-4.
PMID:
22722833
.
Citations:
275
Fields:
Sci
Science
Translation:
Animals
Cells
Vidal M
, Chan DW, Gerstein M, Mann M, Omenn GS, Tagle D, Sechi S. The human proteome - a scientific opportunity for transforming diagnostics, therapeutics, and healthcare. Clin Proteomics. 2012 Jul 03; 9(1):6.
PMID:
22583803
.
Citations:
12
Gulbahce N, Yan H, Dricot A, Padi M, Byrdsong D, Franchi R, Lee DS, Rozenblatt-Rosen O, Mar JC, Calderwood MA, Baldwin A,
Zhao B
, Santhanam B, Braun P, Simonis N, Huh KW, Hellner K, Grace M, Chen A, Rubio R,
Marto JA
, Christakis NA, Kieff E, Roth FP, Roecklein-Canfield J,
Decaprio JA
, Cusick ME,
Quackenbush J
,
Hill DE
, Münger K,
Vidal M
, Barabási AL. Viral perturbations of host networks reflect disease etiology. PLoS Comput Biol. 2012; 8(6):e1002531.
PMID:
22761553
.
Citations:
73
Fields:
Com
Computational Biology
Translation:
Humans
Cells
Baas D, Caussanel-Boude S, Guiraud A, Calhabeu F, Delaune E, Pilot F, Chopin E, Machuca-Gayet I, Vernay A, Bertrand S, Rual JF, Jurdic P,
Hill DE
,
Vidal M
, Schaeffer L, Goillot E. CKIP-1 regulates mammalian and zebrafish myoblast fusion. J Cell Sci. 2012 Aug 15; 125(Pt 16):3790-800.
PMID:
22553210
.
Citations:
10
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Simonis N, Rual JF, Lemmens I, Boxus M, Hirozane-Kishikawa T, Gatot JS, Dricot A, Hao T, Vertommen D, Legros S, Daakour S, Klitgord N, Martin M, Willaert JF, Dequiedt F, Navratil V, Cusick ME, Burny A, Van Lint C,
Hill DE
, Tavernier J, Kettmann R,
Vidal M
, Twizere JC. Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses. Retrovirology. 2012 Mar 29; 9:26.
PMID:
22458338
.
Citations:
46
Fields:
Vir
Virology
Translation:
Humans
Cells
Djebali S, Lagarde J, Kapranov P, Lacroix V, Borel C, Mudge JM, Howald C, Foissac S, Ucla C, Chrast J, Ribeca P, Martin D, Murray RR, Yang X, Ghamsari L, Lin C, Bell I, Dumais E, Drenkow J, Tress ML, Gelpí JL, Orozco M, Valencia A, van Berkum NL, Lajoie BR,
Vidal M
, Stamatoyannopoulos J, Batut P, Dobin A, Harrow J, Hubbard T, Dekker J, Frankish A, Salehi-Ashtiani K, Reymond A, Antonarakis SE, Guigó R, Gingeras TR. Evidence for transcript networks composed of chimeric RNAs in human cells. PLoS One. 2012; 7(1):e28213.
PMID:
22238572
.
Citations:
40
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Maxwell CA, Benítez J, Gómez-Baldó L, Osorio A, Bonifaci N, Fernández-Ramires R, Costes SV, Guinó E, Chen H, Evans GJ, Mohan P, Català I, Petit A, Aguilar H, Villanueva A, Aytes A, Serra-Musach J, Rennert G, Lejbkowicz F, Peterlongo P, Manoukian S, Peissel B, Ripamonti CB, Bonanni B, Viel A, Allavena A, Bernard L, Radice P, Friedman E, Kaufman B, Laitman Y, Dubrovsky M, Milgrom R, Jakubowska A, Cybulski C, Gorski B, Jaworska K, Durda K, Sukiennicki G, Lubinski J, Shugart YY, Domchek SM, Letrero R, Weber BL, Hogervorst FB, Rookus MA, Collee JM, Devilee P, Ligtenberg MJ, Luijt RB, Aalfs CM, Waisfisz Q, Wijnen J, Roozendaal CE, Easton DF, Peock S, Cook M, Oliver C, Frost D, Harrington P, Evans DG, Lalloo F, Eeles R, Izatt L, Chu C, Eccles D, Douglas F, Brewer C, Nevanlinna H, Heikkinen T, Couch FJ, Lindor NM, Wang X, Godwin AK, Caligo MA, Lombardi G, Loman N, Karlsson P, Ehrencrona H, Wachenfeldt Av, Barkardottir RB, Hamann U, Rashid MU, Lasa A, Caldés T, Andrés R, Schmitt M, Assmann V, Stevens K, Offit K, Curado J, Tilgner H, Guigó R, Aiza G, Brunet J, Castellsagué J, Martrat G, Urruticoechea A, Blanco I, Tihomirova L, Goldgar DE, Buys S, John EM, Miron A, Southey M, Daly MB, Schmutzler RK, Wappenschmidt B, Meindl A, Arnold N, Deissler H, Varon-Mateeva R, Sutter C, Niederacher D, Imyamitov E, Sinilnikova OM, Stoppa-Lyonne D, Mazoyer S, Verny-Pierre C, Castera L, de Pauw A, Bignon YJ, Uhrhammer N, Peyrat JP, Vennin P, Fert Ferrer S, Collonge-Rame MA, Mortemousque I, Spurdle AB, Beesley J, Chen X, Healey S, Barcellos-Hoff MH,
Vidal M
, Gruber SB, Lázaro C, Capellá G, McGuffog L, Nathanson KL, Antoniou AC, Chenevix-Trench G, Fleisch MC, Moreno V, Pujana MA. Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. PLoS Biol. 2011 Nov; 9(11):e1001199.
PMID:
22110403
; PMCID:
PMC3217025
.
Citations:
53
Fields:
Bio
Biology
Translation:
Humans
Cells
Anders L, Ke N, Hydbring P, Choi YJ,
Widlund HR
, Chick JM, Zhai H,
Vidal M
, Gygi SP, Braun P, Sicinski P. A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells. Cancer Cell. 2011 Nov 15; 20(5):620-34.
PMID:
22094256
.
Citations:
266
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Schild-Prüfert K, Saito TT, Smolikov S, Gu Y, Hincapie M,
Hill DE
,
Vidal M
, McDonald K, Colaiácovo MP. Organization of the synaptonemal complex during meiosis in Caenorhabditis elegans. Genetics. 2011 Oct; 189(2):411-21.
PMID:
21840865
.
Citations:
49
Fields:
Gen
Genetics
Translation:
Animals
Cells
Evidence for network evolution in an Arabidopsis interactome map. Science. 2011 Jul 29; 333(6042):601-7.
PMID:
21798944
.
Citations:
392
Fields:
Sci
Science
Translation:
Animals
Cells
Yang X, Boehm JS, Yang X, Salehi-Ashtiani K, Hao T, Shen Y, Lubonja R, Thomas SR, Alkan O, Bhimdi T, Green TM, Johannessen CM, Silver SJ, Nguyen C, Murray RR, Hieronymus H, Balcha D, Fan C, Lin C, Ghamsari L,
Vidal M
,
Hahn WC
,
Hill DE
, Root DE. A public genome-scale lentiviral expression library of human ORFs. Nat Methods. 2011 Jun 26; 8(8):659-61.
PMID:
21706014
; PMCID:
PMC3234135
.
Citations:
284
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Humans
Cells
Yu H, Tardivo L, Tam S, Weiner E, Gebreab F, Fan C, Svrzikapa N, Hirozane-Kishikawa T, Rietman E, Yang X, Sahalie J, Salehi-Ashtiani K, Hao T, Cusick ME,
Hill DE
, Roth FP, Braun P,
Vidal M
. Next-generation sequencing to generate interactome datasets. Nat Methods. 2011 Jun; 8(6):478-80.
PMID:
21516116
.
Citations:
131
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Humans
Vidal M
, Cusick ME, Barabási AL. Interactome networks and human disease. Cell. 2011 Mar 18; 144(6):986-98.
PMID:
21414488
.
Citations:
686
Fields:
Cel
Cell Biology
Translation:
Humans
Suzuki Y, St Onge RP, Mani R, King OD, Heilbut A, Labunskyy VM, Chen W, Pham L, Zhang LV, Tong AH, Nislow C, Giaever G,
Gladyshev VN
,
Vidal M
, Schow P, Lehár J, Roth FP. Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection. Nat Methods. 2011 Feb; 8(2):159-64.
PMID:
21217751
.
Citations:
38
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Animals
Charloteaux B, Zhong Q, Dreze M, Cusick ME,
Hill DE
,
Vidal M
. Protein-protein interactions and networks: forward and reverse edgetics. Methods Mol Biol. 2011; 759:197-213.
PMID:
21863489
.
Citations:
14
Fields:
Mol
Molecular Biology
Brehme M,
Vidal M
. A global protein-lipid interactome map. Mol Syst Biol. 2010 Nov 30; 6:443.
PMID:
21119635
.
Citations:
4
Fields:
Com
Computational Biology
Mol
Molecular Biology
Translation:
Animals
Cells
Johannessen CM, Boehm JS, Kim SY, Thomas SR, Wardwell L, Johnson LA, Emery CM, Stransky N, Cogdill AP, Barretina J, Caponigro G, Hieronymus H, Murray RR, Salehi-Ashtiani K,
Hill DE
,
Vidal M
,
Zhao JJ
, Yang X, Alkan O, Kim S, Harris JL, Wilson CJ, Myer VE, Finan PM, Root DE,
Roberts TM
,
Golub T
,
Flaherty KT
, Dummer R, Weber BL,
Sellers WR
, Schlegel R, Wargo JA,
Hahn WC
, Garraway LA. COT drives resistance to RAF inhibition through MAP kinase pathway reactivation. Nature. 2010 Dec 16; 468(7326):968-72.
PMID:
21107320
; PMCID:
PMC3058384
.
Citations:
710
Fields:
Sci
Science
Translation:
Humans
Cells
Giordano-Santini R, Milstein S, Svrzikapa N, Tu D, Johnsen R, Baillie D,
Vidal M
, Dupuy D. An antibiotic selection marker for nematode transgenesis. Nat Methods. 2010 Sep; 7(9):721-3.
PMID:
20729841
.
Citations:
42
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Animals
Yan H, Venkatesan K, Beaver JE, Klitgord N, Yildirim MA, Hao T,
Hill DE
, Cusick ME,
Perrimon N
, Roth FP,
Vidal M
. A genome-wide gene function prediction resource for Drosophila melanogaster. PLoS One. 2010 Aug 12; 5(8):e12139.
PMID:
20711346
.
Citations:
12
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Animals
Wang J, Robida-Stubbs S, Tullet JM, Rual JF,
Vidal M
,
Blackwell TK
. RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition. PLoS Genet. 2010 Aug 05; 6(8).
PMID:
20700440
.
Citations:
95
Fields:
Gen
Genetics
Translation:
Animals
Cells
Mangone M, Manoharan AP, Thierry-Mieg D, Thierry-Mieg J, Han T, Mackowiak SD, Mis E, Zegar C, Gutwein MR, Khivansara V, Attie O, Chen K, Salehi-Ashtiani K,
Vidal M
, Harkins TT, Bouffard P, Suzuki Y, Sugano S, Kohara Y, Rajewsky N, Piano F, Gunsalus KC, Kim JK. The landscape of C. elegans 3'UTRs. Science. 2010 Jul 23; 329(5990):432-5.
PMID:
20522740
.
Citations:
166
Fields:
Sci
Science
Translation:
Animals
Cells
Pilot-Storck F, Chopin E, Rual JF, Baudot A, Dobrokhotov P, Robinson-Rechavi M, Brun C, Cusick ME,
Hill DE
, Schaeffer L,
Vidal M
, Goillot E. Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor. Mol Cell Proteomics. 2010 Jul; 9(7):1578-93.
PMID:
20368287
; PMCID:
PMC2938100
.
Citations:
29
Fields:
Bio
Biochemistry
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Gómez-Baldó L, Schmidt S, Maxwell CA, Bonifaci N, Gabaldón T, Vidalain PO, Senapedis W, Kletke A, Rosing M, Barnekow A, Rottapel R, Capellá G,
Vidal M
, Astrinidis A, Piekorz RP, Pujana MA. TACC3-TSC2 maintains nuclear envelope structure and controls cell division. Cell Cycle. 2010 Mar 15; 9(6):1143-55.
PMID:
20237422
.
Citations:
16
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Dreze M, Monachello D, Lurin C, Cusick ME,
Hill DE
,
Vidal M
, Braun P. High-quality binary interactome mapping. Methods Enzymol. 2010; 470:281-315.
PMID:
20946815
.
Citations:
71
Fields:
Bio
Biochemistry
Translation:
Animals
Cells
Yadav VK, Balaji S, Suresh PS, Liu XS, Lu X, Li Z, Guo XE, Mann JJ, Balapure AK, Gershon MD, Medhamurthy R,
Vidal M
, Karsenty G, Ducy P. Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis. Nat Med. 2010 Mar; 16(3):308-12.
PMID:
20139991
.
Citations:
126
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Animals
Vidal M
. A unifying view of 21st century systems biology. FEBS Lett. 2009 Dec 17; 583(24):3891-4.
PMID:
19913537
.
Citations:
43
Fields:
Bio
Biochemistry
Zhong Q, Simonis N, Li QR, Charloteaux B, Heuze F, Klitgord N, Tam S, Yu H, Venkatesan K,
Mou D
, Swearingen V, Yildirim MA, Yan H, Dricot A, Szeto D, Lin C, Hao T, Fan C, Milstein S, Dupuy D, Brasseur R,
Hill DE
, Cusick ME,
Vidal M
. Edgetic perturbation models of human inherited disorders. Mol Syst Biol. 2009; 5:321.
PMID:
19888216
.
Citations:
193
Fields:
Com
Computational Biology
Mol
Molecular Biology
Translation:
Humans
Dreze M, Charloteaux B, Milstein S, Vidalain PO, Yildirim MA, Zhong Q, Svrzikapa N, Romero V, Laloux G, Brasseur R, Vandenhaute J, Boxem M, Cusick ME,
Hill DE
,
Vidal M
. 'Edgetic' perturbation of a C. elegans BCL2 ortholog. Nat Methods. 2009 Nov; 6(11):843-9.
PMID:
19855391
; PMCID:
PMC2865203
.
Citations:
36
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Animals
Cells
Joubert PE, Meiffren G, Grégoire IP, Pontini G, Richetta C, Flacher M, Azocar O, Vidalain PO,
Vidal M
, Lotteau V, Codogno P, Rabourdin-Combe C, Faure M. Autophagy induction by the pathogen receptor CD46. Cell Host Microbe. 2009 Oct 22; 6(4):354-66.
PMID:
19837375
.
Citations:
129
Fields:
Mic
Microbiology
Translation:
Humans
Cells
Tonikian R, Xin X, Toret CP, Gfeller D, Landgraf C, Panni S, Paoluzi S, Castagnoli L, Currell B, Seshagiri S, Yu H, Winsor B,
Vidal M
, Gerstein MB, Bader GD, Volkmer R, Cesareni G, Drubin DG, Kim PM, Sidhu SS, Boone C. Bayesian modeling of the yeast SH3 domain interactome predicts spatiotemporal dynamics of endocytosis proteins. PLoS Biol. 2009 Oct; 7(10):e1000218.
PMID:
19841731
.
Citations:
93
Fields:
Bio
Biology
Translation:
Animals