Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Kana Wu, Ph.D.


As a trained physician, nutrition and cancer epidemiologist, and a longtime research member of three large cohorts, the Nurses' Health Study, Nurses' Health Study 2, and the Health Professionals Follow-up Study, my research activities focus on studying the relationship between diet, lifestyle, and risk of cancers. To illuminate insight into the complex pathways driving carcinogenesis, I am leading multidisciplinary projects integrating diet, lifestyle, and genetic risk factors with plasma and tumor tissue biomarkers. In another line of research, I examine the contribution of early life exposures and genetic susceptibility to the etiology of early onset cancers.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21CA230873 (WU, KANA) Jul 3, 2018 - Jun 30, 2021
    Integrating diet, lifestyle and tumor tissue molecular subtyping to study the role of adolescent calcium intake on the risk of early onset colorectal neoplasia
    Role: Principal Investigator
  2. R21CA222940 (WU, KANA) Jan 1, 2018 - Dec 31, 2020
    Integrating diet and tissue whole exome sequencing data to study processed meat and colorectal cancer
    Role: Principal Investigator
  3. R03CA197879 (WU, KANA) Jul 1, 2015 - Jun 30, 2017
    Early life risk factors and risk of colorectal neoplasia
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lyu Z, Hang D, He X, Wu K, Cao Y, Rosner B, Chan AT, Ogino S, Li N, Dai M, Giovannucci EL, Song M. Simple Prediction Model for Colorectal Serrated Polyps: Development and External Validation Study in US Prospective Cohorts. Cancer Prev Res (Phila). 2023 Mar 01. PMID: 36857746.
    Citations:    Fields:    
  2. Kim H, Hur J, Wu K, Song M, Wang M, Smith-Warner SA, Zhang X, Giovannucci EL. Total calcium, dairy foods and risk of colorectal cancer: a prospective cohort study of younger US women. Int J Epidemiol. 2023 02 08; 52(1):87-95. PMID: 36315018; PMCID: PMC9908061.
    Citations: 1     Fields:    Translation:Humans
  3. Hang D, Wang L, Fang Z, Du M, Wang K, He X, Khandpur N, Rossato SL, Wu K, Hu Z, Shen H, Ogino S, Chan AT, Giovannucci EL, Zhang FF, Song M. Ultra-processed food consumption and risk of colorectal cancer precursors: results from 3 prospective cohorts. J Natl Cancer Inst. 2023 02 08; 115(2):155-164. PMID: 36477589; PMCID: PMC9905956.
    Citations: 2     Fields:    Translation:Humans
  4. Li X, Joh HK, Hur J, Song M, Zhang X, Cao Y, Wu K, Giovannucci EL. Fructose consumption from different food sources and cardiometabolic biomarkers: cross-sectional associations in US men and women. Am J Clin Nutr. 2023 Mar; 117(3):490-498. PMID: 36811469.
    Citations:    Fields:    Translation:Humans
  5. Zhang Y, Song M, Cao Y, Eliassen AH, Wolpin BM, Stampfer MJ, Willett WC, Wu K, Ng K, Hu FB, Giovannucci EL. Incident Early- and Later-Onset Type 2 Diabetes and Risk of Early- and Later-Onset Cancer: Prospective Cohort Study. Diabetes Care. 2023 01 01; 46(1):120-129. PMID: 36399782; PMCID: PMC9797652.
    Citations:    Fields:    Translation:Humans
  6. Zhang Y, Stopsack KH, Wu K, Song M, Mucci LA, Giovannucci E. Post-diagnostic Zinc Supplement Use and Prostate Cancer Survival Among Men With Nonmetastatic Prostate Cancer. J Urol. 2023 03; 209(3):549-556. PMID: 36453265.
    Citations:    Fields:    Translation:Humans
  7. Wang K, Ma W, Hu Y, Knudsen MD, Nguyen LH, Wu K, Ng K, Wang M, Ogino S, Sun Q, Giovannucci EL, Chan AT, Song M. Endoscopic Screening and Risk of Colorectal Cancer according to Type 2 Diabetes Status. Cancer Prev Res (Phila). 2022 12 01; 15(12):847-856. PMID: 36049216; PMCID: PMC9722520.
    Citations:    Fields:    Translation:HumansPHPublic Health
  8. Ugai T, Liu L, Tabung FK, Hamada T, Langworthy BW, Akimoto N, Haruki K, Takashima Y, Okadome K, Kawamura H, Zhao M, Kahaki SMM, Glickman JN, Lennerz JK, Zhang X, Chan AT, Fuchs CS, Song M, Wang M, Yu KH, Giannakis M, Nowak JA, Meyerhardt JA, Wu K, Ogino S, Giovannucci EL. Prognostic role of inflammatory diets in colorectal cancer overall and in strata of tumor-infiltrating lymphocyte levels. Clin Transl Med. 2022 11; 12(11):e1114. PMID: 36437503; PMCID: PMC9702366.
    Citations:    Fields:    Translation:HumansCells
  9. Lan T, Park Y, Colditz GA, Liu J, Wang M, Wu K, Giovannucci E, Sutcliffe S. Adolescent dietary patterns in relation to later prostate cancer risk and mortality in the NIH-AARP Diet and Health Study. Br J Cancer. 2023 01; 128(1):57-62. PMID: 36316560; PMCID: PMC9814153.
    Citations:    Fields:    Translation:HumansAnimals
  10. Wang F, Ugai T, Haruki K, Wan Y, Akimoto N, Arima K, Zhong R, Twombly TS, Wu K, Yin K, Chan AT, Giannakis M, Nowak JA, Meyerhardt JA, Liang L, Song M, Smith-Warner SA, Zhang X, Giovannucci EL, Willett WC, Ogino S. Healthy and unhealthy plant-based diets in relation to the incidence of colorectal cancer overall and by molecular subtypes. Clin Transl Med. 2022 08; 12(8):e893. PMID: 35998061; PMCID: PMC9398226.
    Citations: 2     Fields:    Translation:HumansCells
  11. Wang L, Knudsen MD, Lo CH, Wang K, He M, Polychronidis G, Hang D, He X, Zhong R, Wu K, Chan AT, Ogino S, Giovannucci EL, Song M. Adherence to a healthy lifestyle in relation to colorectal cancer incidence and all-cause mortality after endoscopic polypectomy: A prospective study in three U.S. cohorts. Int J Cancer. 2022 11 01; 151(9):1523-1534. PMID: 35716133; PMCID: PMC9474593.
    Citations: 1     Fields:    Translation:Humans
  12. Arima K, Zhong R, Ugai T, Zhao M, Haruki K, Akimoto N, Lau MC, Okadome K, Mehta RS, Väyrynen JP, Kishikawa J, Twombly TS, Shi S, Fujiyoshi K, Kosumi K, Ogata Y, Baba H, Wang F, Wu K, Song M, Zhang X, Fuchs CS, Sears CL, Willett WC, Giovannucci EL, Meyerhardt JA, Garrett WS, Huttenhower C, Chan AT, Nowak JA, Giannakis M, Ogino S. Western-Style Diet, pks Island-Carrying Escherichia coli, and Colorectal Cancer: Analyses From Two Large Prospective Cohort Studies. Gastroenterology. 2022 10; 163(4):862-874. PMID: 35760086; PMCID: PMC9509428.
    Citations: 7     Fields:    Translation:HumansCells
  13. Luo X, Yang W, Joshi AD, Wu K, Simon TG, Yuan C, Jin L, Long L, Kim MN, Lo CH, Liu X, Abrams TA, Wolpin BM, Chan AT, Giovannucci EL, Zhang X. Gallstones and risk of cancers of the liver, biliary tract and pancreas: a prospective study within two U.S. cohorts. Br J Cancer. 2022 10; 127(6):1069-1075. PMID: 35715632; PMCID: PMC9470543.
    Citations:    Fields:    Translation:Humans
  14. Yuan C, Joh HK, Wang QL, Zhang Y, Smith-Warner SA, Wang M, Song M, Cao Y, Zhang X, Zoltick ES, Hur J, Chan AT, Meyerhardt JA, Ogino S, Ng K, Giovannucci EL, Wu K. Sugar-sweetened beverage and sugar consumption and colorectal cancer incidence and mortality according to anatomic subsite. Am J Clin Nutr. 2022 06 07; 115(6):1481-1489. PMID: 35470384; PMCID: PMC9170474.
    Citations: 3     Fields:    Translation:Humans
  15. Akimoto N, Väyrynen JP, Zhao M, Ugai T, Fujiyoshi K, Borowsky J, Zhong R, Haruki K, Arima K, Lau MC, Kishikawa J, Twombly TS, Takashima Y, Song M, Zhang X, Wu K, Chan AT, Meyerhardt JA, Giannakis M, Nowak JA, Ogino S. Desmoplastic Reaction, Immune Cell Response, and Prognosis in Colorectal Cancer. Front Immunol. 2022; 13:840198. PMID: 35392092; PMCID: PMC8980356.
    Citations:    Fields:    Translation:Humans
  16. Wang F, Chandler PD, Zeleznik OA, Wu K, Wu Y, Yin K, Song R, Avila-Pacheco J, Clish CB, Meyerhardt JA, Zhang X, Song M, Ogino S, Lee IM, Eliassen AH, Liang L, Smith-Warner SA, Willett WC, Giovannucci EL. Plasma Metabolite Profiles of Red Meat, Poultry, and Fish Consumption, and Their Associations with Colorectal Cancer Risk. Nutrients. 2022 Feb 25; 14(5). PMID: 35267954; PMCID: PMC8912563.
    Citations: 2     Fields:    Translation:Animals
  17. Wan Y, Wu K, Wang L, Yin K, Song M, Giovannucci EL, Willett WC. Dietary fat and fatty acids in relation to risk of colorectal cancer. Eur J Nutr. 2022 Jun; 61(4):1863-1873. PMID: 35048194.
    Citations: 4     Fields:    Translation:HumansAnimals
  18. Hang D, Zeleznik OA, Lu J, Joshi AD, Wu K, Hu Z, Shen H, Clish CB, Liang L, Eliassen AH, Ogino S, Meyerhardt JA, Chan AT, Song M. Plasma metabolomic profiles for colorectal cancer precursors in women. Eur J Epidemiol. 2022 Apr; 37(4):413-422. PMID: 35032257; PMCID: PMC9189062.
    Citations: 1     Fields:    Translation:Humans
  19. Zhang Y, Wu K, Chan AT, Meyerhardt JA, Giovannucci EL. Long-Term Statin Use, Total Cholesterol Level, and Risk of Colorectal Cancer: A Prospective Cohort Study. Am J Gastroenterol. 2022 01 01; 117(1):158-166. PMID: 34730560; PMCID: PMC9200604.
    Citations: 3     Fields:    Translation:Humans
  20. Väyrynen JP, Haruki K, Lau MC, Väyrynen SA, Ugai T, Akimoto N, Zhong R, Zhao M, Dias Costa A, Borowsky J, Bell P, Takashima Y, Fujiyoshi K, Arima K, Kishikawa J, Shi SS, Twombly TS, Song M, Wu K, Chan AT, Zhang X, Fuchs CS, Meyerhardt JA, Giannakis M, Ogino S, Nowak JA. Spatial Organization and Prognostic Significance of NK and NKT-like Cells via Multimarker Analysis of the Colorectal Cancer Microenvironment. Cancer Immunol Res. 2022 02; 10(2):215-227. PMID: 34937729; PMCID: PMC8816895.
    Citations: 3     Fields:    Translation:HumansCells
  21. Polychronidis G, Wang K, Lo CH, Wang L, He M, Knudsen MD, Wu K, Joshi AD, Ogino S, Giovannucci EL, Chan AT, Song M. Gallstone Disease and Risk of Conventional Adenomas and Serrated Polyps: A Prospective Study. Cancer Epidemiol Biomarkers Prev. 2021 12; 30(12):2346-2349. PMID: 34620626; PMCID: PMC8643323.
    Citations: 1     Fields:    Translation:Humans
  22. Lan T, Park Y, Colditz GA, Liu J, Wang M, Wu K, Giovannucci E, Sutcliffe S. Adolescent Plant Product Intake in Relation to Later Prostate Cancer Risk and Mortality in the NIH-AARP Diet and Health Study. J Nutr. 2021 10 01; 151(10):3223-3231. PMID: 34383904.
    Citations: 2     Fields:    Translation:HumansAnimals
  23. Ugai T, Väyrynen JP, Lau MC, Borowsky J, Akimoto N, Väyrynen SA, Zhao M, Zhong R,