Harvard Catalyst Profiles

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Pierre Regent Leblanc, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Cha Y, Park TY, Leblanc P, Kim KS. Current Status and Future Perspectives on Stem Cell-Based Therapies for Parkinson's Disease. J Mov Disord. 2023 Jan; 16(1):22-41. PMID: 36628428; PMCID: PMC9978267.
  2. Song B, Feldmann JW, Cao S, Feitosa M, Kong Y, Kim W, Schweitzer A, Leblanc P, Schweitzer JS, Kim KS. A Pitx3-deficient developmental mouse model for fine motor, olfactory, and gastrointestinal symptoms of Parkinson's disease. Neurobiol Dis. 2022 08; 170:105777. PMID: 35636646; PMCID: PMC9425627.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Cha Y, Leblanc P, Hong YJ, Kim KS. Integrative analysis of mitochondrial metabolic dynamics in reprogramming human fibroblast cells. STAR Protoc. 2022 06 17; 3(2):101401. PMID: 35600932; PMCID: PMC9115322.
    Citations:    Fields:    Translation:HumansCells
  4. Kim J, Jeon J, Song B, Lee N, Ko S, Cha Y, Leblanc P, Seo H, Kim KS. Spotting-based differentiation of functional dopaminergic progenitors from human pluripotent stem cells. Nat Protoc. 2022 03; 17(3):890-909. PMID: 35140411; PMCID: PMC9511827.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  5. Cha Y, Kim T, Jeon J, Jang Y, Kim PB, Lopes C, Leblanc P, Cohen BM, Kim KS. SIRT2 regulates mitochondrial dynamics and reprogramming via MEK1-ERK-DRP1 and AKT1-DRP1 axes. Cell Rep. 2021 12 28; 37(13):110155. PMID: 34965411; PMCID: PMC8780843.
    Citations: 2     Fields:    Translation:HumansCells
  6. Schweitzer JS, Song B, Herrington TM, Park TY, Lee N, Ko S, Jeon J, Cha Y, Kim K, Li Q, Henchcliffe C, Kaplitt M, Neff C, Rapalino O, Seo H, Lee IH, Kim J, Kim T, Petsko GA, Ritz J, Cohen BM, Kong SW, Leblanc P, Carter BS, Kim KS. Personalized iPSC-Derived Dopamine Progenitor Cells for Parkinson's Disease. N Engl J Med. 2020 05 14; 382(20):1926-1932. PMID: 32402162; PMCID: PMC7288982.
    Citations: 87     Fields:    Translation:HumansAnimalsCells
  7. Schweitzer JS, Song B, Leblanc PR, Feitosa M, Carter BS, Kim KS. Columnar Injection for Intracerebral Cell Therapy. Oper Neurosurg (Hagerstown). 2020 03 01; 18(3):321-328. PMID: 31214702.
    Citations: 2     Fields:    Translation:HumansAnimals
  8. Park TY, Jang Y, Kim W, Shin J, Toh HT, Kim CH, Yoon HS, Leblanc P, Kim KS. Chloroquine modulates inflammatory autoimmune responses through Nurr1 in autoimmune diseases. Sci Rep. 2019 10 29; 9(1):15559. PMID: 31664129.
    Citations: 11     Fields:    Translation:HumansCells
  9. Sonntag KC, Song B, Lee N, Jung JH, Cha Y, Leblanc P, Neff C, Kong SW, Carter BS, Schweitzer J, Kim KS. Pluripotent stem cell-based therapy for Parkinson's disease: Current status and future prospects. Prog Neurobiol. 2018 09; 168:1-20. PMID: 29653250.
    Citations: 29     Fields:    Translation:HumansCells
  10. Li B, Zeng Y, Reeves PM, Ran C, Liu Q, Qu X, Liang Y, Liu Z, Yuan J, Leblanc PR, Ye Z, Sluder AE, Gelfand JA, Brauns TA, Chen H, Poznansky MC. AMD3100 Augments the Efficacy of Mesothelin-Targeted, Immune-Activating VIC-008 in Mesothelioma by Modulating Intratumoral Immunosuppression. Cancer Immunol Res. 2018 05; 6(5):539-551. PMID: 29511032.
    Citations: 17     Fields:    Translation:AnimalsCells
  11. Kimizuka Y, Callahan JJ, Huang Z, Morse K, Katagiri W, Shigeta A, Bronson R, Takeuchi S, Shimaoka Y, Chan MPK, Zeng Y, Li B, Chen H, Tan RYY, Dwyer C, Mulley T, Leblanc P, Goudie C, Gelfand J, Tsukada K, Brauns T, Poznansky MC, Bean D, Kashiwagi S. Semiconductor diode laser device adjuvanting intradermal vaccine. Vaccine. 2017 04 25; 35(18):2404-2412. PMID: 28365253.
    Citations: 9     Fields:    Translation:AnimalsPHPublic Health
  12. Kim CH, Leblanc P, Kim KS. 4-amino-7-chloroquinoline derivatives for treating Parkinson's disease: implications for drug discovery. Expert Opin Drug Discov. 2016; 11(4):337-41. PMID: 26924734.
    Citations: 8     Fields:    Translation:Humans
  13. Leblanc P, Moon M, Kim W, Jeong I, Kim CH, Kim KS. Production of Nurr-1 Specific Polyclonal Antibodies Free of Cross-reactivity Against Its Close Homologs, Nor1 and Nur77. J Vis Exp. 2015 Aug 17; (102):e52963. PMID: 26325389.
    Citations: 1     Fields:    
  14. Brauns T, Leblanc P, Gelfand JA, Poznanski M. Could mycobacterial Hsp70-containing fusion protein lead the way to an affordable therapeutic cancer vaccine? Expert Rev Vaccines. 2015 Mar; 14(3):435-46. PMID: 25496347.
    Citations: 3     Fields:    Translation:HumansCells
  15. Moon M, Jeong I, Kim CH, Kim J, Lee PK, Mook-Jung I, Leblanc P, Kim KS. Correlation between orphan nuclear receptor Nurr1 expression and amyloid deposition in 5XFAD mice, an animal model of Alzheimer's disease. J Neurochem. 2015 Jan; 132(2):254-62. PMID: 25156412.
    Citations: 19     Fields:    Translation:AnimalsCells
  16. Leblanc P, Moise L, Luza C, Chantaralawan K, Lezeau L, Yuan J, Field M, Richer D, Boyle C, Martin WD, Fishman JB, Berg EA, Baker D, Zeigler B, Mais DE, Taylor W, Coleman R, Warren HS, Gelfand JA, De Groot AS, Brauns T, Poznansky MC. VaxCelerate II: rapid development of a self-assembling vaccine for Lassa fever. Hum Vaccin Immunother. 2014; 10(10):3022-38. PMID: 25483693.
    Citations: 13     Fields:    Translation:AnimalsCells
  17. Kashiwagi S, Yuan J, Forbes B, Hibert ML, Lee EL, Whicher L, Goudie C, Yang Y, Chen T, Edelblute B, Collette B, Edington L, Trussler J, Nezivar J, Leblanc P, Bronson R, Tsukada K, Suematsu M, Dover J, Brauns T, Gelfand J, Poznansky MC. Near-infrared laser adjuvant for influenza vaccine. PLoS One. 2013; 8(12):e82899. PMID: 24349390.
    Citations: 15     Fields:    Translation:AnimalsCellsPHPublic Health
  18. Huang Y, Yuan J, Righi E, Kamoun WS, Ancukiewicz M, Nezivar J, Santosuosso M, Martin JD, Martin MR, Vianello F, Leblanc P, Munn LL, Huang P, Duda DG, Fukumura D, Jain RK, Poznansky MC. Vascular normalizing doses of antiangiogenic treatment reprogram the immunosuppressive tumor microenvironment and enhance immunotherapy. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17561-6. PMID: 23045683.
    Citations: 381     Fields:    Translation:HumansAnimals
  19. Leblanc PR, Yuan J, Brauns T, Gelfand JA, Poznansky MC. Accelerated vaccine development against emerging infectious diseases. Hum Vaccin Immunother. 2012 Jul; 8(7):1010-2. PMID: 22777091.
    Citations: 2     Fields:    Translation:Humans
  20. Righi E, Kashiwagi S, Yuan J, Santosuosso M, Leblanc P, Ingraham R, Forbes B, Edelblute B, Collette B, Xing D, Kowalski M, Mingari MC, Vianello F, Birrer M, Orsulic S, Dranoff G, Poznansky MC. CXCL12/CXCR4 blockade induces multimodal antitumor effects that prolong survival in an immunocompetent mouse model of ovarian cancer. Cancer Res. 2011 Aug 15; 71(16):5522-5534. PMID: 21742774.
    Citations: 106     Fields:    Translation:Animals
  21. Santosuosso M, Righi E, Hill ED, Leblanc PR, Kodish B, Mylvaganam HN, Siddappa NB, Stevceva L, Hu SL, Ghebremichael M, Chenine AL, Hovav AH, Ruprecht RM, Poznansky MC. R5-SHIV induces multiple defects in T cell function during early infection of rhesus macaques including accumulation of T reg cells in lymph nodes. PLoS One. 2011 Apr 05; 6(4):e18465. PMID: 21483689.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  22. Kim CH, Leung A, Huh YH, Yang E, Kim DJ, Leblanc P, Ryu H, Kim K, Kim DW, Garland EM, Raj SR, Biaggioni I, Robertson D, Kim KS. Norepinephrine deficiency is caused by combined abnormal mRNA processing and defective protein trafficking of dopamine beta-hydroxylase. J Biol Chem. 2011 Mar 18; 286(11):9196-204. PMID: 21209083; PMCID: PMC3059068.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  23. Santosuosso M, Righi E, Lindstrom V, Leblanc PR, Poznansky MC. HIV-1 envelope protein gp120 is present at high concentrations in secondary lymphoid organs of individuals with chronic HIV-1 infection. J Infect Dis. 2009 Oct 01; 200(7):1050-3. PMID: 19698075.
    Citations: 44     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.