Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Omid Cameron Farokhzad, M.D.

Title
Institution
Department
Address
Phone
Fax

Mentoring
completed student projects
Development of Targeted Nanoparticle to Facilitate Drug Delivery for Treating Atherosclerois
Summer, 06/25/07 - 08/17/07

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01HL127464 (TABAS, IRA A) Jan 1, 2016 - Dec 31, 2020
    NIH
    Enhancing Inflammation Resolution in Atherosclerosis via Targeted Nanoparticle-Mediated Delivery of Biologics
    Role: Principal Investigator
  2. R01EB015419 (FAROKHZAD, OMID C) Apr 15, 2012 - Mar 31, 2017
    NIH
    Development of FcRn-Targeted Nanoparticles for Efficient Oral Delivery of Insulin
    Role: Principal Investigator
  3. K08EB003647 (FAROKHZAD, OMID C) Mar 1, 2005 - Mar 30, 2011
    NIH
    Development of Disease-Specific Drug Delivery Vehicles
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lin YX, Wang Y, Ding J, Jiang A, Wang J, Yu M, Blake S, Liu S, Bieberich CJ, Farokhzad OC, Mei L, Wang H, Shi J. Reactivation of the tumor suppressor PTEN by mRNA nanoparticles enhances antitumor immunity in preclinical models. Sci Transl Med. 2021 06 23; 13(599). PMID: 34162754.
    Citations: 1     Fields:    Translation:HumansCells
  2. Molinaro R, Yu M, Sausen G, Bichsel CA, Corbo C, Folco EJ, Lee GY, Liu Y, Tesmenitsky Y, Shvartz E, Sukhova GK, Kloss F, Croce KJ, Farokhzad OC, Shi J, Libby P. Targeted delivery of Protein Arginine Deiminase-4 inhibitors to limit arterial intimal NETosis and preserve endothelial integrity. Cardiovasc Res. 2021 Mar 05. PMID: 33751034.
    Citations: 3     Fields:    
  3. Chen W, Liu C, Ji X, Joseph J, Tang Z, Ouyang J, Xiao Y, Kong N, Joshi N, Farokhzad OC, Tao W, Xie T. Stanene-Based Nanosheets for ß-Elemene Delivery and Ultrasound-Mediated Combination Cancer Therapy. Angew Chem Int Ed Engl. 2021 03 22; 60(13):7155-7164. PMID: 33434327.
    Citations: 5     Fields:    Translation:HumansCells
  4. Liu Y, Wang J, Xiong Q, Hornburg D, Tao W, Farokhzad OC. Nano-Bio Interactions in Cancer: From Therapeutics Delivery to Early Detection. Acc Chem Res. 2021 01 19; 54(2):291-301. PMID: 33180454.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  5. Corbo C, Li AA, Poustchi H, Lee GY, Stacks S, Molinaro R, Ma P, Platt T, Behzadi S, Langer R, Farias V, Farokhzad OC. Analysis of the Human Plasma Proteome Using Multi-Nanoparticle Protein Corona for Detection of Alzheimer's Disease. Adv Healthc Mater. 2021 01; 10(2):e2000948. PMID: 33169521.
    Citations:    Fields:    Translation:Humans
  6. Tang Z, Kong N, Zhang X, Liu Y, Hu P, Mou S, Liljeström P, Shi J, Tan W, Kim JS, Cao Y, Langer R, Leong KW, Farokhzad OC, Tao W. A materials-science perspective on tackling COVID-19. Nat Rev Mater. 2020 Oct 14; 1-14. PMID: 33078077.
    Citations: 21     
  7. Islam MA, Rice J, Reesor E, Zope H, Tao W, Lim M, Ding J, Chen Y, Aduluso D, Zetter BR, Farokhzad OC, Shi J. Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice. Biomaterials. 2021 01; 266:120431. PMID: 33099060.
    Citations: 7     Fields:    Translation:AnimalsCells
  8. Xiao Y, Tang Z, Wang J, Liu C, Kong N, Farokhzad OC, Tao W. Oral Insulin Delivery Platforms: Strategies To Address the Biological Barriers. Angew Chem Int Ed Engl. 2020 11 02; 59(45):19787-19795. PMID: 32705745.
    Citations: 2     Fields:    Translation:Humans
  9. Blume JE, Manning WC, Troiano G, Hornburg D, Figa M, Hesterberg L, Platt TL, Zhao X, Cuaresma RA, Everley PA, Ko M, Liou H, Mahoney M, Ferdosi S, Elgierari EM, Stolarczyk C, Tangeysh B, Xia H, Benz R, Siddiqui A, Carr SA, Ma P, Langer R, Farias V, Farokhzad OC. Rapid, deep and precise profiling of the plasma proteome with multi-nanoparticle protein corona. Nat Commun. 2020 07 22; 11(1):3662. PMID: 32699280.
    Citations: 11     Fields:    Translation:Humans
  10. Tao W, Yurdagul A, Kong N, Li W, Wang X, Doran AC, Feng C, Wang J, Islam MA, Farokhzad OC, Tabas I, Shi J. siRNA nanoparticles targeting CaMKII? in lesional macrophages improve atherosclerotic plaque stability in mice. Sci Transl Med. 2020 07 22; 12(553). PMID: 32718990.
    Citations: 11     Fields:    Translation:AnimalsCells
  11. Li Y, Ding J, Xu X, Shi R, Saw PE, Wang J, Chung S, Li W, Aljaeid BM, Lee RJ, Tao W, Teng L, Farokhzad OC, Shi J. Dual Hypoxia-Targeting RNAi Nanomedicine for Precision Cancer Therapy. Nano Lett. 2020 07 08; 20(7):4857-4863. PMID: 32479088.
    Citations: 4     Fields:    Translation:HumansCells
  12. Hu K, Xie L, Zhang Y, Hanyu M, Yang Z, Nagatsu K, Suzuki H, Ouyang J, Ji X, Wei J, Xu H, Farokhzad OC, Liang SH, Wang L, Tao W, Zhang MR. Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy. Nat Commun. 2020 06 08; 11(1):2778. PMID: 32513979.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  13. Kong N, Ji X, Wang J, Sun X, Chen G, Fan T, Liang W, Zhang H, Xie A, Farokhzad OC, Tao W. ROS-Mediated Selective Killing Effect of Black Phosphorus: Mechanistic Understanding and Its Guidance for Safe Biomedical Applications. Nano Lett. 2020 05 13; 20(5):3943-3955. PMID: 32243175.
    Citations: 21     Fields:    Translation:HumansCells
  14. Saw PE, Xu X, Zhang M, Cao S, Farokhzad OC, Wu J. Nanostructure Engineering by Simple Tuning of Lipid Combinations. Angew Chem Int Ed Engl. 2020 04 06; 59(15):6249-6252. PMID: 32017368.
    Citations: 1     Fields:    Translation:AnimalsCells
  15. Son S, Nam J, Zenkov I, Ochyl LJ, Xu Y, Scheetz L, Shi J, Farokhzad OC, Moon JJ. Sugar-Nanocapsules Imprinted with Microbial Molecular Patterns for mRNA Vaccination. Nano Lett. 2020 03 11; 20(3):1499-1509. PMID: 32023415.
    Citations: 9     Fields:    Translation:AnimalsCellsPHPublic Health
  16. Liu Y, Zou Y, Feng C, Lee A, Yin J, Chung R, Park JB, Rizos H, Tao W, Zheng M, Farokhzad OC, Shi B. Charge Conversional Biomimetic Nanocomplexes as a Multifunctional Platform for Boosting Orthotopic Glioblastoma RNAi Therapy. Nano Lett. 2020 03 11; 20(3):1637-1646. PMID: 32013452.
    Citations: 8     Fields:    Translation:AnimalsCells
  17. Li S, Saw PE, Lin C, Nie Y, Tao W, Farokhzad OC, Zhang L, Xu X. Redox-responsive polyprodrug nanoparticles for targeted siRNA delivery and synergistic liver cancer therapy. Biomaterials. 2020 03; 234:119760. PMID: 31945619.
    Citations: 9     Fields:    Translation:HumansCells
  18. Kong N, Tao W, Ling X, Wang J, Xiao Y, Shi S, Ji X, Shajii A, Gan ST, Kim NY, Duda DG, Xie T, Farokhzad OC, Shi J. Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition. Sci Transl Med. 2019 12 18; 11(523). PMID: 31852795.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  19. Ji X, Kang Y, Ouyang J, Chen Y, Artzi D, Zeng X, Xiao Y, Feng C, Qi B, Kim NY, Saw PE, Kong N, Farokhzad OC, Tao W. Synthesis of Ultrathin Biotite Nanosheets as an Intelligent Theranostic Platform for Combination Cancer Therapy. Adv Sci (Weinh). 2019 Oct 02; 6(19):1901211. PMID: 31592423.
    Citations: 16     
  20. Ouyang J, Feng C, Ji X, Li L, Gutti HK, Kim NY, Artzi D, Xie A, Kong N, Liu YN, Tearney GJ, Sui X, Tao W, Farokhzad OC. 2D Monoelemental Germanene Quantum Dots: Synthesis as Robust Photothermal Agents for Photonic Cancer Nanomedicine. Angew Chem Int Ed Engl. 2019 09 16; 58(38):13405-13410. PMID: 31365775.
    Citations: 13     Fields:    Translation:Humans
  21. Saw PE, Yao H, Lin C, Tao W, Farokhzad OC, Xu X. Stimuli-Responsive Polymer-Prodrug Hybrid Nanoplatform for Multistage siRNA Delivery and Combination Cancer Therapy. . 2019 09 11; 19(9):5967-5974. PMID: 31381852.
    Citations: 9     Translation:HumansCells
  22. Tao W, Kong N, Ji X, Zhang Y, Sharma A, Ouyang J, Qi B, Wang J, Xie N, Kang C, Zhang H, Farokhzad OC, Kim JS. Emerging two-dimensional monoelemental materials (Xenes) for biomedical applications. Chem Soc Rev. 2019 Jun 04; 48(11):2891-2912. PMID: 31120049.
    Citations: 39     Fields:    Translation:HumansAnimals
  23. Tao W, Wang J, Parak WJ, Farokhzad OC, Shi J. Nanobuffering of pH-Responsive Polymers: A Known but Sometimes Overlooked Phenomenon and Its Biological Applications. ACS Nano. 2019 05 28; 13(5):4876-4882. PMID: 30985108.
    Citations: 7     Fields:    
  24. Shi S, Kong N, Feng C, Shajii A, Bejgrowicz C, Tao W, Farokhzad OC. Drug Delivery Strategies for the Treatment of Metabolic Diseases. Adv Healthc Mater. 2019 06; 8(12):e1801655. PMID: 30957991.
    Citations: 6     Fields:    Translation:HumansAnimals
  25. Ling X, Tu J, Wang J, Shajii A, Kong N, Feng C, Zhang Y, Yu M, Xie T, Bharwani Z, Aljaeid BM, Shi B, Tao W, Farokhzad OC. Glutathione-Responsive Prodrug Nanoparticles for Effective Drug Delivery and Cancer Therapy. ACS Nano. 2019 01 22; 13(1):357-370. PMID: 30485068.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  26. Islam MA, Xu Y, Tao W, Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, Kantoff PW, Farokhzad OC, Zetter BR, Shi J. Author Correction: Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA. Nat Biomed Eng. 2018 Dec; 2(12):968. PMID: 31015729.
    Citations: 2     Fields:    
  27. Yu M, Ortega CA, Si K, Molinaro R, Schoen FJ, Leitao RFC, Xu X, Mahmoudi M, Ahn S, Liu J, Saw PE, Lee IH, Brayner MMB, Lotfi A, Shi J, Libby P, Jon S, Farokhzad OC. Nanoparticles targeting extra domain B of fibronectin-specific to the atherosclerotic lesion types III, IV, and V-enhance plaque detection and cargo delivery. Theranostics. 2018; 8(21):6008-6024. PMID: 30613278.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  28. Lim JM, Cai T, Mandaric S, Chopra S, Han H, Jang S, Il Choi W, Langer R, Farokhzad OC, Karnik R. Drug loading augmentation in polymeric nanoparticles using a coaxial turbulent jet mixer: Yong investigator perspective. J Colloid Interface Sci. 2019 Mar 07; 538:45-50. PMID: 30500466.
    Citations:    Fields:    
  29. Xu X, Wu J, Liu S, Saw PE, Tao W, Li Y, Krygsman L, Yegnasubramanian S, De Marzo AM, Shi J, Bieberich CJ, Farokhzad OC. Redox-Responsive Nanoparticle-Mediated Systemic RNAi for Effective Cancer Therapy. Small. 2018 10; 14(41):e1802565. PMID: 30230235.
    Citations: 12     Fields:    Translation:HumansCells
  30. Islam MA, Xu Y, Tao W, Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, Kantoff PW, Farokhzad OC, Zetter BR, Shi J. Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA. Nat Biomed Eng. 2018 11; 2(11):850-864. PMID: 31015614.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  31. Tao W, Ji X, Zhu X, Li L, Wang J, Zhang Y, Saw PE, Li W, Kong N, Islam MA, Gan T, Zeng X, Zhang H, Mahmoudi M, Tearney GJ, Farokhzad OC. Two-Dimensional Antimonene-Based Photonic Nanomedicine for Cancer Theranostics. . 2018 Sep; 30(38):e1802061. PMID: 30043416.
    Citations: 39     Translation:Humans
  32. Ling X, Chen X, Riddell IA, Tao W, Wang J, Hollett G, Lippard SJ, Farokhzad OC, Shi J, Wu J. Glutathione-Scavenging Poly(disulfide amide) Nanoparticles for the Effective Delivery of Pt(IV) Prodrugs and Reversal of Cisplatin Resistance. . 2018 07 11; 18(7):4618-4625. PMID: 29902013.
    Citations: 14     Translation:HumansAnimalsCells
  33. Parak WJ, Chan WWC, Chhowalla M, Farokhzad O, Glotzer S, Gogotsi Y, Hammond PT, Hersam MC, Javey A, Kagan CR, Kataoka K, Khademhosseini A, Kotov NA, Lee ST, Lee YH, Li Y, Millstone J, Mulvaney PA, Nel AE, Nordlander PJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee ATS, Willson CG, Weiss PS. Helmuth Möhwald (1946-2018). ACS Nano. 2018 Apr 24; 12(4):3053-3055. PMID: 29676563.
    Citations:    Fields:    
  34. Zhu X, Ji X, Kong N, Chen Y, Mahmoudi M, Xu X, Ding L, Tao W, Cai T, Li Y, Gan T, Barrett A, Bharwani Z, Chen H, Farokhzad OC. Intracellular Mechanistic Understanding of 2D MoS2 Nanosheets for Anti-Exocytosis-Enhanced Synergistic Cancer Therapy. ACS Nano. 2018 03 27; 12(3):2922-2938. PMID: 29406760.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  35. Zheng M, Tao W, Zou Y, Farokhzad OC, Shi B. Nanotechnology-Based Strategies for siRNA Brain Delivery for Disease Therapy. Trends Biotechnol. 2018 05; 36(5):562-575. PMID: 29422412.
    Citations: 25     Fields:    Translation:HumansAnimals
  36. Chan WWC, Chhowalla M, Farokhzad O, Glotzer S, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kataoka K, Khademhosseini A, Kotov NA, Lee ST, Li Y, Millstone J, Möhwald H, Mulvaney PC, Nel AE, Nordlander PJ, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee ATS, Willson CG, Fernandez LE, Weiss PS. A Big Year Ahead for Nano in 2018. ACS Nano. 2017 12 26; 11(12):11755-11757. PMID: 29294604.
    Citations:    Fields:    
  37. Bertrand N, Grenier P, Mahmoudi M, Lima EM, Appel EA, Dormont F, Lim JM, Karnik R, Langer R, Farokhzad OC. Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics. Nat Commun. 2017 10 03; 8(1):777. PMID: 28974673.
    Citations: 89     Fields:    Translation:AnimalsCells
  38. Mahmoudi M, Yu M, Serpooshan V, Wu JC, Langer R, Lee RT, Karp JM, Farokhzad OC. Multiscale technologies for treatment of ischemic cardiomyopathy. Nat Nanotechnol. 2017 09 06; 12(9):845-855. PMID: 28875984.
    Citations: 26     Fields:    Translation:HumansAnimals
  39. Wang J, Tao W, Chen X, Farokhzad OC, Liu G. Emerging Advances in Nanotheranostics with Intelligent Bioresponsive Systems. Theranostics. 2017; 7(16):3915-3919. PMID: 29109787.
    Citations: 11     Fields:    Translation:Humans
  40. Behzadi S, Luther GA, Harris MB, Farokhzad OC, Mahmoudi M. Nanomedicine for safe healing of bone trauma: Opportunities and challenges. Biomaterials. 2017 Nov; 146:168-182. PMID: 28918266.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  41. Kakkar A, Traverso G, Farokhzad OC, Weissleder R, Langer R. Evolution of macromolecular complexity in drug delivery systems. Nat Rev Chem. 2017 Aug; 1(8). PMID: 31286060.
    Citations: 31     
  42. Yu M, Amengual J, Menon A, Kamaly N, Zhou F, Xu X, Saw PE, Lee SJ, Si K, Ortega CA, Choi WI, Lee IH, Bdour Y, Shi J, Mahmoudi M, Jon S, Fisher EA, Farokhzad OC. Targeted Nanotherapeutics Encapsulating Liver X Receptor Agonist GW3965 Enhance Antiatherogenic Effects without Adverse Effects on Hepatic Lipid Metabolism in Ldlr-/- Mice. Adv Healthc Mater. 2017 Oct; 6(20). PMID: 28730752.
    Citations: 13     Fields:    Translation:AnimalsCells
  43. Behzadi S, Serpooshan V, Tao W, Hamaly MA, Alkawareek MY, Dreaden EC, Brown D, Alkilany AM, Farokhzad OC, Mahmoudi M. Cellular uptake of nanoparticles: journey inside the cell. Chem Soc Rev. 2017 Jul 17; 46(14):4218-4244. PMID: 28585944.
    Citations: 230     Fields:    Translation:HumansCells
  44. Tao W, Ji X, Xu X, Islam MA, Li Z, Chen S, Saw PE, Zhang H, Bharwani Z, Guo Z, Shi J, Farokhzad OC. Antimonene Quantum Dots: Synthesis and Application as Near-Infrared Photothermal Agents for Effective Cancer Therapy. Angew Chem Int Ed Engl. 2017 09 18; 56(39):11896-11900. PMID: 28640986.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  45. Shi B, Zheng M, Tao W, Chung R, Jin D, Ghaffari D, Farokhzad OC. Challenges in DNA Delivery and Recent Advances in Multifunctional Polymeric DNA Delivery Systems. Biomacromolecules. 2017 Aug 14; 18(8):2231-2246. PMID: 28661127.
    Citations: 25     Fields:    Translation:HumansAnimals
  46. Xu X, Saw PE, Tao W, Li Y, Ji X, Bhasin S, Liu Y, Ayyash D, Rasmussen J, Huo M, Shi J, Farokhzad OC. ROS-Responsive Polyprodrug Nanoparticles for Triggered Drug Delivery and Effective Cancer Therapy. . 2017 Sep; 29(33). PMID: 28681981.
    Citations: 30     Translation:Humans
  47. Xu X, Saw PE, Tao W, Li Y, Ji X, Yu M, Mahmoudi M, Rasmussen J, Ayyash D, Zhou Y, Farokhzad OC, Shi J. Tumor Microenvironment-Responsive Multistaged Nanoplatform for Systemic RNAi and Cancer Therapy. . 2017 07 12; 17(7):4427-4435. PMID: 28636389.
    Citations: 29     Translation:HumansAnimalsCells
  48. Zhu X, Tao W, Liu D, Wu J, Guo Z, Ji X, Bharwani Z, Zhao L, Zhao X, Farokhzad OC, Shi J. Surface De-PEGylation Controls Nanoparticle-Mediated siRNA Delivery In Vitro and In Vivo. Theranostics. 2017; 7(7):1990-2002. PMID: 28638484.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  49. Chopra S, Bertrand N, Lim JM, Wang A, Farokhzad OC, Karnik R. Design of Insulin-Loaded Nanoparticles Enabled by Multistep Control of Nanoprecipitation and Zinc Chelation. ACS Appl Mater Interfaces. 2017 Apr 05; 9(13):11440-11450. PMID: 28323414.
    Citations: 3     Fields:    
  50. Xu X, Wu J, Liu Y, Saw PE, Tao W, Yu M, Zope H, Si M, Victorious A, Rasmussen J, Ayyash D, Farokhzad OC, Shi J. Multifunctional Envelope-Type siRNA Delivery Nanoparticle Platform for Prostate Cancer Therapy. ACS Nano. 2017 03 28; 11(3):2618-2627. PMID: 28240870.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  51. Corbo C, Molinaro R, Tabatabaei M, Farokhzad OC, Mahmoudi M. Personalized protein corona on nanoparticles and its clinical implications. Biomater Sci. 2017 Feb 28; 5(3):378-387. PMID: 28133653.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  52. Khademhosseini A, Chan WW, Chhowalla M, Glotzer SC, Gogotsi Y, Hafner JH, Hammond PT, Hersam MC, Javey A, Kagan CR, Kotov NA, Lee ST, Li Y, Möhwald H, Mulvaney PA, Nel AE, Parak WJ, Penner RM, Rogach AL, Schaak RE, Stevens MM, Wee AT, Brinker J, Chen X, Chi L, Crommie M, Dekker C, Farokhzad O, Gerber C, Ginger DS, Irvine DJ, Kiessling LL, Kostarelos K, Landes C, Lee T, Leggett GJ, Liang XJ, Liz-Marzán L, Millstone J, Odom TW, Ozcan A, Prato M, Rao CN, Sailor MJ, Weiss E, Weiss PS. Nanoscience and Nanotechnology Cross Borders. ACS Nano. 2017 02 28; 11(2):1123-1126. PMID: 28199099.
    Citations:    Fields:    
  53. Saw PE, Yu M, Choi M, Lee E, Jon S, Farokhzad OC. Hyper-cell-permeable micelles as a drug delivery carrier for effective cancer therapy. Biomaterials. 2017 04; 123:118-126. PMID: 28167390.
    Citations: 5     Fields:    Translation:AnimalsCells
  54. Shi J, Kantoff PW, Wooster R, Farokhzad OC. Cancer nanomedicine: progress, challenges and opportunities. Nat Rev Cancer. 2017 01; 17(1):20-37. PMID: 27834398.
    Citations: 667     Fields:    Translation:Humans
  55. Kamaly N, He JC, Ausiello DA, Farokhzad OC. Nanomedicines for renal disease: current status and future applications. Nat Rev Nephrol. 2016 Dec; 12(12):738-753. PMID: 27795549.
    Citations: 33     Fields:    Translation:Humans
  56. Saw PE, Park J, Jon S, Farokhzad OC. A drug-delivery strategy for overcoming drug resistance in breast cancer through targeting of oncofetal fibronectin. Nanomedicine. 2017 02; 13(2):713-722. PMID: 27769887.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  57. Caracciolo G, Farokhzad OC, Mahmoudi M. Biological Identity of Nanoparticles In Vivo: Clinical Implications of the Protein Corona. Trends Biotechnol. 2017 03; 35(3):257-264. PMID: 27663778.
    Citations: 54     Fields:    Translation:HumansAnimals
  58. Cisterna BA, Kamaly N, Choi WI, Tavakkoli A, Farokhzad OC, Vilos C. Targeted nanoparticles for colorectal cancer. Nanomedicine (Lond). 2016 Sep; 11(18):2443-56. PMID: 27529192.
    Citations: 21     Fields:    Translation:Humans
  59. Liu Y, Gunda V, Zhu X, Xu X, Wu J, Askhatova D, Farokhzad OC, Parangi S, Shi J. Theranostic near-infrared fluorescent nanoplatform for imaging and systemic siRNA delivery to metastatic anaplastic thyroid cancer. Proc Natl Acad Sci U S A. 2016 07 12; 113(28):7750-5. PMID: 27342857.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  60. Xu X, Wu J, Liu Y, Yu M, Zhao L, Zhu X, Bhasin S, Li Q, Ha E, Shi J, Farokhzad OC. Ultra-pH-Responsive and Tumor-Penetrating Nanoplatform for Targeted siRNA Delivery with Robust Anti-Cancer Efficacy. Angew Chem Int Ed Engl. 2016 06 13; 55(25):7091-7094. PMID: 27140428.
    Citations: 37     Fields:    Translation:HumansCells
  61. Xue Y, Xu X, Zhang XQ, Farokhzad OC, Langer R. Preventing diet-induced obesity in mice by adipose tissue transformation and angiogenesis using targeted nanoparticles. Proc Natl Acad Sci U S A. 2016 May 17; 113(20):5552-7. PMID: 27140638.
    Citations: 37     Fields:    Translation:AnimalsCells
  62. Kamaly N, Fredman G, Fojas JJ, Subramanian M, Choi WI, Zepeda K, Vilos C, Yu M, Gadde S, Wu J, Milton J, Carvalho Leitao R, Rosa Fernandes L, Hasan M, Gao H, Nguyen V, Harris J, Tabas I, Farokhzad OC. Targeted Interleukin-10 Nanotherapeutics Developed with a Microfluidic Chip Enhance Resolution of Inflammation in Advanced Atherosclerosis. ACS Nano. 2016 05 24; 10(5):5280-92. PMID: 27100066.
    Citations: 33     Fields:    Translation:Animals
  63. Kamaly N, Yameen B, Wu J, Farokhzad OC. Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release. Chem Rev. 2016 Feb 24; 116(4):2602-63. PMID: 26854975.
    Citations: 261     Fields:    Translation:Cells
  64. Zhu X, Wu J, Shan W, Tao W, Zhao L, Lim JM, D'Ortenzio M, Karnik R, Huang Y, Shi J, Farokhzad OC. Polymeric Nanoparticles Amenable to Simultaneous Installation of Exterior Targeting and Interior Therapeutic Proteins. Angew Chem Int Ed Engl. 2016 Mar 01; 55(10):3309-12. PMID: 26846161.
    Citations: 13     Fields:    Translation:HumansCells
  65. Chung BL, Toth MJ, Kamaly N, Sei YJ, Becraft J, Mulder WJ, Fayad ZA, Farokhzad OC, Kim Y, Langer R. Nanomedicines for Endothelial Disorders. Nano Today. 2015 Dec 01; 10(6):759-776. PMID: 26955397.
    Citations: 6     
  66. Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamaly N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R. Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle. Sci Transl Med. 2015 Nov 18; 7(314):314ra183. PMID: 26582898.
    Citations: 92     Fields:    Translation:HumansAnimalsCells
  67. Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R. Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug. Nat Commun. 2015 Oct 27; 6:8692. PMID: 26503691.
    Citations: 113     Fields:    Translation:HumansAnimalsCells
  68. Yu M, Wu J, Shi J, Farokhzad OC. Nanotechnology for protein delivery: Overview and perspectives. J Control Release. 2016 10 28; 240:24-37. PMID: 26458789.
    Citations: 41     Fields:    Translation:HumansAnimals
  69. Farokhzad OC. Nanotechnology: Platelet mimicry. Nature. 2015 Oct 01; 526(7571):47-8. PMID: 26375011.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  70. Yameen B, Vilos C, Choi WI, Whyte A, Huang J, Pollit L, Farokhzad OC. Drug Delivery Nanocarriers from a Fully Degradable PEG-Conjugated Polyester with a Reduction-Responsive Backbone. Chemistry. 2015 Aug 03; 21(32):11325-9. PMID: 26177931.
    Citations: 5     Fields:    Translation:Humans
  71. Wu J, Zhao L, Xu X, Bertrand N, Choi WI, Yameen B, Shi J, Shah V, Mulvale M, MacLean JL, Farokhzad OC. Hydrophobic Cysteine Poly(disulfide)-based Redox-Hypersensitive Nanoparticle Platform for Cancer Theranostics. Angew Chem Int Ed Engl. 2015 Aug 03; 54(32):9218-23. PMID: 26119453.
    Citations: 15     Fields:    Translation:HumansCells
  72. Stary G, Olive A, Radovic-Moreno AF, Gondek D, Alvarez D, Basto PA, Perro M, Vrbanac VD, Tager AM, Shi J, Yethon JA, Farokhzad OC, Langer R, Starnbach MN, von Andrian UH. VACCINES. A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells. Science. 2015 Jun 19; 348(6241):aaa8205. PMID: 26089520.
    Citations: 144     Fields:    Translation:AnimalsCellsPHPublic Health
  73. Zhu X, Xu Y, Solis LM, Tao W, Wang L, Behrens C, Xu X, Zhao L, Liu D, Wu J, Zhang N, Wistuba II, Farokhzad OC, Zetter BR, Shi J. Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment. Proc Natl Acad Sci U S A. 2015 Jun 23; 112(25):7779-84. PMID: 26056316.
    Citations: 39     Fields:    Translation:Humans
  74. Saw PE, Park J, Lee E, Ahn S, Lee J, Kim H, Kim J, Choi M, Farokhzad OC, Jon S. Effect of PEG pairing on the efficiency of cancer-targeting liposomes. Theranostics. 2015; 5(7):746-54. PMID: 25897339.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  75. Pridgen EM, Alexis F, Farokhzad OC. Polymeric nanoparticle drug delivery technologies for oral delivery applications. Expert Opin Drug Deliv. 2015; 12(9):1459-73. PMID: 25813361.
    Citations: 34     Fields:    Translation:HumansAnimals
  76. Fredman G, Kamaly N, Spolitu S, Milton J, Ghorpade D, Chiasson R, Kuriakose G, Perretti M, Farokzhad O, Tabas I. Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice. Sci Transl Med. 2015 Feb 18; 7(275):275ra20. PMID: 25695999.
    Citations: 101     Fields:    Translation:Animals
  77. Leoni G, Neumann PA, Kamaly N, Quiros M, Nishio H, Jones HR, Sumagin R, Hilgarth RS, Alam A, Fredman G, Argyris I, Rijcken E, Kusters D, Reutelingsperger C, Perretti M, Parkos CA, Farokhzad OC, Neish AS, Nusrat A. Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair. J Clin Invest. 2015 Mar 02; 125(3):1215-27. PMID: 25664854.
    Citations: 105     Fields:    Translation:HumansAnimalsCells
  78. Xu X, Ho W, Zhang X, Bertrand N, Farokhzad O. Cancer nanomedicine: from targeted delivery to combination therapy. Trends Mol Med. 2015 Apr; 21(4):223-32. PMID: 25656384.
    Citations: 110     Fields:    Translation:HumansAnimalsCells
  79. Maldonado RA, LaMothe RA, Ferrari JD, Zhang AH, Rossi RJ, Kolte PN, Griset AP, O'Neil C, Altreuter DH, Browning E, Johnston L, Farokhzad OC, Langer R, Scott DW, von Andrian UH, Kishimoto TK. Polymeric synthetic nanoparticles for the induction of antigen-specific immunological tolerance. Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):E156-65. PMID: 25548186.
    Citations: 144     Fields:    Translation:HumansAnimalsCells
  80. Choi WI, Kamaly N, Riol-Blanco L, Lee IH, Wu J, Swami A, Vilos C, Yameen B, Yu M, Shi J, Tabas I, von Andrian UH, Jon S, Farokhzad OC. A solvent-free thermosponge nanoparticle platform for efficient delivery of labile proteins. Nano Lett. 2014 Nov 12; 14(11):6449-55. PMID: 25333768.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  81. Zhang XQ, Even-Or O, Xu X, van Rosmalen M, Lim L, Gadde S, Farokhzad OC, Fisher EA. Nanoparticles containing a liver X receptor agonist inhibit inflammation and atherosclerosis. Adv Healthc Mater. 2015 Jan 28; 4(2):228-36. PMID: 25156796.
    Citations: 28     Fields:    Translation:AnimalsCells
  82. Wu J, Kamaly N, Shi J, Zhao L, Xiao Z, Hollett G, John R, Ray S, Xu X, Zhang X, Kantoff PW, Farokhzad OC. Development of multinuclear polymeric nanoparticles as robust protein nanocarriers. Angew Chem Int Ed Engl. 2014 Aug 18; 53(34):8975-9. PMID: 24990548.
    Citations: 28     Fields:    
  83. Swami A, Reagan MR, Basto P, Mishima Y, Kamaly N, Glavey S, Zhang S, Moschetta M, Seevaratnam D, Zhang Y, Liu J, Memarzadeh M, Wu J, Manier S, Shi J, Bertrand N, Lu ZN, Nagano K, Baron R, Sacco A, Roccaro AM, Farokhzad OC, Ghobrial IM. Engineered nanomedicine for myeloma and bone microenvironment targeting. Proc Natl Acad Sci U S A. 2014 Jul 15; 111(28):10287-92. PMID: 24982170.
    Citations: 79     Fields:    Translation:HumansAnimalsCells
  84. Yameen B, Choi WI, Vilos C, Swami A, Shi J, Farokhzad OC. Insight into nanoparticle cellular uptake and intracellular targeting. J Control Release. 2014 Sep 28; 190:485-99. PMID: 24984011.
    Citations: 135     Fields:    Translation:HumansCells
  85. Pridgen EM, Alexis F, Farokhzad OC. Polymeric nanoparticle technologies for oral drug delivery. Clin Gastroenterol Hepatol. 2014 Oct; 12(10):1605-10. PMID: 24981782.
    Citations: 22     Fields:    Translation:Humans
  86. Lim JM, Swami A, Gilson LM, Chopra S, Choi S, Wu J, Langer R, Karnik R, Farokhzad OC. Ultra-high throughput synthesis of nanoparticles with homogeneous size distribution using a coaxial turbulent jet mixer. ACS Nano. 2014 Jun 24; 8(6):6056-65. PMID: 24824296.
    Citations: 25     Fields:    Translation:HumansCells
  87. Gadde S, Even-Or O, Kamaly N, Hasija A, Gagnon PG, Adusumilli KH, Erakovic A, Pal AK, Zhang XQ, Kolishetti N, Shi J, Fisher EA, Farokhzad OC. Development of therapeutic polymeric nanoparticles for the resolution of inflammation. Adv Healthc Mater. 2014 Sep; 3(9):1448-1456. PMID: 24659608.
    Citations: 10     Fields:    Translation:Animals
  88. Shi J, Xu Y, Xu X, Zhu X, Pridgen E, Wu J, Votruba AR, Swami A, Zetter BR, Farokhzad OC. Hybrid lipid-polymer nanoparticles for sustained siRNA delivery and gene silencing. Nanomedicine. 2014 Jul; 10(5):897-900. PMID: 24650883.
    Citations: 13     Fields:    Translation:HumansCells
  89. Gendelman HE, Balogh LP, Bawa R, Bradbury M, Chang EH, Chiu W, Farokhzad O, Foldvari M, Lanza G, Wang K. The 4th Annual Meeting of the American Society for Nanomedicine. J Neuroimmune Pharmacol. 2014 Mar; 9 Suppl 1:S1-3. PMID: 24550132.
    Citations:    Fields:    Translation:Humans
  90. Ilyinskii PO, Roy CJ, O'Neil CP, Browning EA, Pittet LA, Altreuter DH, Alexis F, Tonti E, Shi J, Basto PA, Iannacone M, Radovic-Moreno AF, Langer RS, Farokhzad OC, von Andrian UH, Johnston LP, Kishimoto TK. Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine release. Vaccine. 2014 May 19; 32(24):2882-95. PMID: 24593999.
    Citations: 49     Fields:    Translation:AnimalsCells
  91. Wang AZ, Farokhzad OC. Current progress of aptamer-based molecular imaging. J Nucl Med. 2014 Mar; 55(3):353-6. PMID: 24525205.
    Citations: 24     Fields:    Translation:Humans
  92. Kim Y, Lobatto ME, Kawahara T, Lee Chung B, Mieszawska AJ, Sanchez-Gaytan BL, Fay F, Senders ML, Calcagno C, Becraft J, Tun Saung M, Gordon RE, Stroes ES, Ma M, Farokhzad OC, Fayad ZA, Mulder WJ, Langer R. Probing nanoparticle translocation across the permeable endothelium in experimental atherosclerosis. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):1078-83. PMID: 24395808.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  93. Pridgen EM, Alexis F, Kuo TT, Levy-Nissenbaum E, Karnik R, Blumberg RS, Langer R, Farokhzad OC. Transepithelial transport of Fc-targeted nanoparticles by the neonatal fc receptor for oral delivery. Sci Transl Med. 2013 Nov 27; 5(213):213ra167. PMID: 24285486.
    Citations: 87     Fields:    Translation:Animals
  94. Bertrand N, Wu J, Xu X, Kamaly N, Farokhzad OC. Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. Adv Drug Deliv Rev. 2014 Feb; 66:2-25. PMID: 24270007.
    Citations: 460     Fields:    Translation:HumansAnimals
  95. Valencia PM, Pridgen EM, Rhee M, Langer R, Farokhzad OC, Karnik R. Microfluidic platform for combinatorial synthesis and optimization of targeted nanoparticles for cancer therapy. ACS Nano. 2013 Dec 23; 7(12):10671-80. PMID: 24215426.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  96. Xu X, Xie K, Zhang XQ, Pridgen EM, Park GY, Cui DS, Shi J, Wu J, Kantoff PW, Lippard SJ, Langer R, Walker GC, Farokhzad OC. Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):18638-43. PMID: 24167294.
    Citations: 82     Fields:    Translation:HumansCells
  97. Gianella A, Mieszawska AJ, Hoeben FJ, Janssen HM, Jarzyna PA, Cormode DP, Costa KD, Rao S, Farokhzad OC, Langer R, Fayad ZA, Mulder WJ. Synthesis and in vitro evaluation of a multifunctional and surface-switchable nanoemulsion platform. Chem Commun (Camb). 2013 Oct 21; 49(82):9392-4. PMID: 23877789.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  98. Kim Y, Fay F, Cormode DP, Sanchez-Gaytan BL, Tang J, Hennessy EJ, Ma M, Moore K, Farokhzad OC, Fisher EA, Mulder WJ, Langer R, Fayad ZA. Single step reconstitution of multifunctional high-density lipoprotein-derived nanomaterials using microfluidics. ACS Nano. 2013 Nov 26; 7(11):9975-83. PMID: 24079940.
    Citations: 29     Fields:    Translation:AnimalsCells
  99. Kim Y, Lee Chung B, Ma M, Mulder WJ, Fayad ZA, Farokhzad OC, Langer R. Correction to Mass Production and Size Control of Lipid-Polymer Hybrid Nanoparticles through Controlled Microvortices. Nano Lett. 2013 Oct 9; 13(10):4997. PMID: 24041197.
    Citations:    
  100. Mieszawska AJ, Kim Y, Gianella A, van Rooy I, Priem B, Labarre MP, Ozcan C, Cormode DP, Petrov A, Langer R, Farokhzad OC, Fayad ZA, Mulder WJ. Synthesis of polymer-lipid nanoparticles for image-guided delivery of dual modality therapy. Bioconjug Chem. 2013 Sep 18; 24(9):1429-34. PMID: 23957728.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  101. Lim JM, Bertrand N, Valencia PM, Rhee M, Langer R, Jon S, Farokhzad OC, Karnik R. Parallel microfluidic synthesis of size-tunable polymeric nanoparticles using 3D flow focusing towards in vivo study. Nanomedicine. 2014 Feb; 10(2):401-9. PMID: 23969105.
    Citations: 18     Fields:    Translation:HumansAnimals
  102. Park J, Park S, Kim S, Lee IH, Saw PE, Lee K, Kim YC, Kim YJ, Farokhzad OC, Jeong YY, Jon S. HER2-specific aptide conjugated magneto-nanoclusters for potential breast cancer imaging and therapy. J Mater Chem B. 2013 Sep 28; 1(36):4576-4583. PMID: 32261200.
    Citations: 1     Fields:    
  103. Johnstone TC, Kulak N, Pridgen EM, Farokhzad OC, Langer R, Lippard SJ. Nanoparticle encapsulation of mitaplatin and the effect thereof on in vivo properties. ACS Nano. 2013 Jul 23; 7(7):5675-83. PMID: 23697579.
    Citations: 20     Fields:    Translation:AnimalsCells
  104. Kamaly N, Fredman G, Subramanian M, Gadde S, Pesic A, Cheung L, Fayad ZA, Langer R, Tabas I, Farokhzad OC. Development and in vivo efficacy of targeted polymeric inflammation-resolving nanoparticles. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6506-11. PMID: 23533277.
    Citations: 67     Fields:    Translation:AnimalsCells
  105. Prabhakar U, Maeda H, Jain RK, Sevick-Muraca EM, Zamboni W, Farokhzad OC, Barry ST, Gabizon A, Grodzinski P, Blakey DC. Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology. Cancer Res. 2013 Apr 15; 73(8):2412-7. PMID: 23423979.
    Citations: 358     Fields:    Translation:HumansAnimals
  106. Zhao W, Cui CH, Bose S, Guo D, Shen C, Wong WP, Halvorsen K, Farokhzad OC, Teo GS, Phillips JA, Dorfman DM, Karnik R, Karp JM. Bioinspired multivalent DNA network for capture and release of cells. Proc Natl Acad Sci U S A. 2012 Nov 27; 109(48):19626-31. PMID: 23150586.
    Citations: 46     Fields:    Translation:HumansCells
  107. Salvador-Morales C, Valencia PM, Gao W, Karnik R, Farokhzad OC. Spontaneous formation of heterogeneous patches on polymer-lipid core-shell particle surfaces during self-assembly. Small. 2013 Feb 25; 9(4):511-7. PMID: 23109494.
    Citations: 5     Fields:    
  108. Xiao Z, Ji C, Shi J, Pridgen EM, Frieder J, Wu J, Farokhzad OC. DNA self-assembly of targeted near-infrared-responsive gold nanoparticles for cancer thermo-chemotherapy. Angew Chem Int Ed Engl. 2012 Nov 19; 51(47):11853-7. PMID: 23081716.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  109. Valencia PM, Pridgen EM, Perea B, Gadde S, Sweeney C, Kantoff PW, Bander NH, Lippard SJ, Langer R, Karnik R, Farokhzad OC. Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles. Nanomedicine (Lond). 2013 May; 8(5):687-98. PMID: 23075285.
    Citations: 24     Fields:    Translation:HumansCells
  110. Valencia PM, Farokhzad OC, Karnik R, Langer R. Microfluidic technologies for accelerating the clinical translation of nanoparticles. Nat Nanotechnol. 2012 Oct; 7(10):623-9. PMID: 23042546.
    Citations: 102     Fields:    Translation:Humans
  111. Zhang XQ, Xu X, Bertrand N, Pridgen E, Swami A, Farokhzad OC. Interactions of nanomaterials and biological systems: Implications to personalized nanomedicine. Adv Drug Deliv Rev. 2012 Oct; 64(13):1363-84. PMID: 22917779.
    Citations: 57     Fields:    Translation:HumansAnimalsCells
  112. Farokhzad OC. Using ligands to target cancer cells. Clin Adv Hematol Oncol. 2012 Aug; 10(8):543-4. PMID: 23073055.
    Citations: 3     Fields:    Translation:HumansCells
  113. Kim Y, Lee Chung B, Ma M, Mulder WJ, Fayad ZA, Farokhzad OC, Langer R. Mass production and size control of lipid-polymer hybrid nanoparticles through controlled microvortices. Nano Lett. 2012 Jul 11; 12(7):3587-91. PMID: 22716029.
    Citations: 41     Fields:    
  114. Graf N, Bielenberg DR, Kolishetti N, Muus C, Banyard J, Farokhzad OC, Lippard SJ. a(V)ß(3) integrin-targeted PLGA-PEG nanoparticles for enhanced anti-tumor efficacy of a Pt(IV) prodrug. ACS Nano. 2012 May 22; 6(5):4530-9. PMID: 22584163.
    Citations: 49     Fields:    Translation:HumansCells
  115. Xiao Z, Farokhzad OC. Aptamer-functionalized nanoparticles for medical applications: challenges and opportunities. ACS Nano. 2012 May 22; 6(5):3670-6. PMID: 22574989.
    Citations: 28     Fields:    Translation:Humans
  116. Mieszawska AJ, Gianella A, Cormode DP, Zhao Y, Meijerink A, Langer R, Farokhzad OC, Fayad ZA, Mulder WJ. Engineering of lipid-coated PLGA nanoparticles with a tunable payload of diagnostically active nanocrystals for medical imaging. Chem Commun (Camb). 2012 Jun 14; 48(47):5835-7. PMID: 22555311.
    Citations: 19     Fields:    
  117. Radovic-Moreno AF, Lu TK, Puscasu VA, Yoon CJ, Langer R, Farokhzad OC. Surface charge-switching polymeric nanoparticles for bacterial cell wall-targeted delivery of antibiotics. ACS Nano. 2012 May 22; 6(5):4279-87. PMID: 22471841.
    Citations: 70     Fields:    Translation:Cells
  118. Hrkach J, Von Hoff D, Mukkaram Ali M, Andrianova E, Auer J, Campbell T, De Witt D, Figa M, Figueiredo M, Horhota A, Low S, McDonnell K, Peeke E, Retnarajan B, Sabnis A, Schnipper E, Song JJ, Song YH, Summa J, Tompsett D, Troiano G, Van Geen Hoven T, Wright J, LoRusso P, Kantoff PW, Bander NH, Sweeney C, Farokhzad OC, Langer R, Zale S. Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile. Sci Transl Med. 2012 Apr 04; 4(128):128ra39. PMID: 22491949.
    Citations: 311     Fields:    Translation:HumansAnimalsCells
  119. Kamaly N, Xiao Z, Valencia PM, Radovic-Moreno AF, Farokhzad OC. Targeted polymeric therapeutic nanoparticles: design, development and clinical translation. Chem Soc Rev. 2012 Apr 07; 41(7):2971-3010. PMID: 22388185.
    Citations: 305     Fields:    Translation:Humans
  120. Xiao Z, Levy-Nissenbaum E, Alexis F, Lupták A, Teply BA, Chan JM, Shi J, Digga E, Cheng J, Langer R, Farokhzad OC. Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection. ACS Nano. 2012 Jan 24; 6(1):696-704. PMID: 22214176.
    Citations: 45     Fields:    Translation:HumansCells
  121. Chan JM, Rhee JW, Drum CL, Bronson RT, Golomb G, Langer R, Farokhzad OC. In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid-polymeric nanoparticles. Proc Natl Acad Sci U S A. 2011 Nov 29; 108(48):19347-52. PMID: 22087004.
    Citations: 38     Fields:    Translation:Animals
  122. Wang AZ, Langer R, Farokhzad OC. Nanoparticle delivery of cancer drugs. Annu Rev Med. 2012; 63:185-98. PMID: 21888516.
    Citations: 359     Fields:    Translation:Humans
  123. Gao W, Farokhzad OC. Self-propelled microrockets to capture and isolate circulating tumor cells. Angew Chem Int Ed Engl. 2011 Aug 01; 50(32):7220-1. PMID: 21728224.
    Citations: 1     Fields:    Translation:HumansCells
  124. Shi J, Xiao Z, Votruba AR, Vilos C, Farokhzad OC. Differentially charged hollow core/shell lipid-polymer-lipid hybrid nanoparticles for small interfering RNA delivery. Angew Chem Int Ed Engl. 2011 Jul 25; 50(31):7027-31. PMID: 21698724.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  125. Shi J, Xiao Z, Kamaly N, Farokhzad OC. Self-assembled targeted nanoparticles: evolution of technologies and bench to bedside translation. Acc Chem Res. 2011 Oct 18; 44(10):1123-34. PMID: 21692448.
    Citations: 104     Fields:    Translation:HumansAnimals
  126. Valencia PM, Hanewich-Hollatz MH, Gao W, Karim F, Langer R, Karnik R, Farokhzad OC. Effects of ligands with different water solubilities on self-assembly and properties of targeted nanoparticles. Biomaterials. 2011 Sep; 32(26):6226-33. PMID: 21658757.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  127. Rhee M, Valencia PM, Rodriguez MI, Langer R, Farokhzad OC, Karnik R. Synthesis of size-tunable polymeric nanoparticles enabled by 3D hydrodynamic flow focusing in single-layer microchannels. Adv Mater. 2011 Mar 25; 23(12):H79-83. PMID: 21433105.
    Citations: 38     Fields:    
  128. Dhar S, Kolishetti N, Lippard SJ, Farokhzad OC. Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo. Proc Natl Acad Sci U S A. 2011 Feb 01; 108(5):1850-5. PMID: 21233423.
    Citations: 146     Fields:    Translation:HumansAnimals
  129. Burgess P, Hutt PB, Farokhzad OC, Langer R, Minick S, Zale S. On firm ground: IP protection of therapeutic nanoparticles. Nat Biotechnol. 2010 Dec; 28(12):1267-70. PMID: 21139609.
    Citations: 19     Fields:    
  130. Gao W, Chan JM, Farokhzad OC. pH-Responsive nanoparticles for drug delivery. Mol Pharm. 2010 Dec 06; 7(6):1913-20. PMID: 20836539.
    Citations: 106     Fields:    
  131. Kolishetti N, Dhar S, Valencia PM, Lin LQ, Karnik R, Lippard SJ, Langer R, Farokhzad OC. Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):17939-44. PMID: 20921363.
    Citations: 122     Fields:    Translation:Humans
  132. Shi J, Votruba AR, Farokhzad OC, Langer R. Nanotechnology in drug delivery and tissue engineering: from discovery to applications. Nano Lett. 2010 Sep 08; 10(9):3223-30. PMID: 20726522.
    Citations: 233     Fields:    
  133. Gao W, Langer R, Farokhzad OC. Poly(ethylene glycol) with observable shedding. Angew Chem Int Ed Engl. 2010 Sep 03; 49(37):6567-71. PMID: 20677297.
    Citations: 11     Fields:    Translation:Cells
  134. Shi J, Votruba AR, Farokhzad OC, Langer R. Nanotechnology in Drug Delivery and Tissue Engineering: From Discovery to Applications. Nano Letters. 2010; Epub ahead of print.
  135. Gao W, Langer R, Farokhzad OC. Poly(ethylene glycol) with Observable Shedding. Angew Chem Int Ed Engl. 2010; Epub ahead of print.
  136. Ludwig FN, Hossainy SF, Svensson B, Sharkawy A, Cima M, Farokhzad OC, Magana J, Von Oepen R, Chow M, Webler WE, Yribarren TR, Ehrenreich KJ. Magnetically sensitive drug carriers and delivery devices. 2010.
  137. Farokhzad OC, Levy-Nissenbaum E, Langer RS, Alexis F. Oligonucleotide systems for targeted intracellular delivery. 2010.
  138. Farokhzad OC, Jon SY, Langer RS. Controlled release nanoparticle having bound oligonucleotide for targeted delivery. 2010.
  139. Shi J, Alexis F, Iannacone M, Moseman A, Basto P, Langer R, Farokhzad OC, von Andrian U. Targeting of antigen presenting cells with immunonanotherapeutics. 2010.
  140. Alexis F, Shi J, Iannacone M, Moseman A, Basto P, Langer R, Farokhzad OC, von Andrian U. Adjuvant incorporation in immunonanotherapeutics. 2010.
  141. Lippard SJ, Dhar S, Farokhzad OC, Kolishetti N, Gu FX. Nanostructures for drug delivery. 2010.
  142. Shi J, Alexis F, Iannacone M, Moseman A, Basto P, Langer R, Farokhzad OC, von Andrian U, Tonti E. Targeting of antigen presenting cells with immunonanotherapeutics. 2010.
  143. Iannacone M, von Andrian U, Farokhzad OC, Alexis F, Basto P, Shi J, Moseman A, Langer R, Tonti E. Nicotine immunonanotherapeutics. 2010.
  144. Farokhzad OC, Salvador-Morales C, Gao W, Zhang L, Chen JM, Langer RS. Particles with multiple functionalized surface domains. 2010.
  145. Iannacone M, Alexis F, Basto P, Moseman A, Shi J, Langer R, Farokhzad OC, von Andrian U, Tonti E. Immunonanotherapeutics that provide IgG humoral response without T-cell antigen. 2010.
  146. Alexis F, Iannacone M, Shi J, Basto P, Moseman A, von Andrian U, Langer R, Farokhzad OC, Tonti E. Adjuvant incorporation in immunonanotherapeutics. 2010.
  147. von Andrian U, Farokhzad OC, Alexis F, Iannacone M, Basto P, Shi J, Moseman A, Langer R. Nicotine immunonanotherapeutics. 2010.
  148. Von Andrian UH, Farokhzad OC, Langer RS, Junt T, Moseman A, Zhang L, Basto P, Iannacone M, Alexis F. Vaccine nanotechnology. 2010.
  149. Wang AZ, Yuet K, Zhang L, Gu FX, Huynh-Le M, Radovic-Moreno AF, Kantoff PW, Bander NH, Langer R, Farokhzad OC. ChemoRad nanoparticles: a novel multifunctional nanoparticle platform for targeted delivery of concurrent chemoradiation. Nanomedicine (Lond). 2010 Apr; 5(3):361-8. PMID: 20394530.
    Citations: 20     Fields:    Translation:HumansCells
  150. Valencia PM, Basto PA, Zhang L, Rhee M, Langer R, Farokhzad OC, Karnik R. Single-step assembly of homogenous lipid-polymeric and lipid-quantum dot nanoparticles enabled by microfluidic rapid mixing. ACS Nano. 2010 Mar 23; 4(3):1671-9. PMID: 20166699.
    Citations: 54     Fields:    Translation:Cells
  151. Mamo T, Moseman EA, Kolishetti N, Salvador-Morales C, Shi J, Kuritzkes DR, Langer R, von Andrian U, Farokhzad OC. Emerging nanotechnology approaches for HIV/AIDS treatment and prevention. Nanomed. 2010; 5(2):269-85.
  152. Mamo T, Moseman EA, Kolishetti N, Salvador-Morales C, Shi J, Kuritzkes DR, Langer R, von Andrian U, Farokhzad OC. Emerging nanotechnology approaches for HIV/AIDS treatment and prevention. Nanomedicine (Lond). 2010 Feb; 5(2):269-85. PMID: 20148638.
    Citations: 51     Fields:    Translation:HumansAnimalsPHPublic Health
  153. Karnik R, Gu FX, Basto P, Cannizzaro C, Khademhosseini A, Langer RS, Farokhzad OC. Microfluidic synthesis of organic nanoparticles. 2010.
  154. Alexis F, Zhang L, Radovic-Moreno AF, Gu FX, Basto P, Levy-Nissenbaum E, Chan J, Langer RS, Farokhzad OC. Poly (amino acid) targeting moieties. 2010.
  155. Chan JM, Zhang L, Tong R, Ghosh D, Gao W, Liao G, Yuet KP, Gray D, Rhee JW, Cheng J, Golomb G, Libby P, Langer R, Farokhzad OC. Spatiotemporal controlled delivery of nanoparticles to injured vasculature. Proc Natl Acad Sci U S A. 2010 Feb 02; 107(5):2213-8. PMID: 20133865.
    Citations: 67     Fields:    Translation:HumansAnimalsCells
  156. Gao W, Xiao Z, Radovic-Moreno A, Shi J, Langer R, Farokhzad OC. Progress in siRNA delivery using multifunctional nanoparticles. Methods Mol Biol. 2010; 629:53-67. PMID: 20387142.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  157. Alexis F, Pridgen EM, Langer R, Farokhzad OC. Nanoparticle technologies for cancer therapy. Handb Exp Pharmacol. 2010; (197):55-86. PMID: 20217526.
    Citations: 65     Fields:    Translation:HumansAnimals
  158. Chan JM, Valencia PM, Zhang L, Langer R, Farokhzad OC. Polymeric nanoparticles for drug delivery. Methods Mol Biol. 2010; 624:163-75. PMID: 20217595.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  159. Langer RS, Farokhzad OC, Chan JM. Endothelial basement membrane targeting peptide ligands. 2009.
  160. Radovic-Moreno AF, Zhang L, Langer RS, Farokhzad OC. Polymer-encapsulated reverse micelles. 2009.
  161. Zhang L, Radovic-Moreno AF, Gu FX, Alexis F, Langer RS, Farokhzad OC. Amphiphilic compound assisted nanoparticles for targeted delivery. 2009.
  162. Wang AZ, Farokhzad OC, Zhang L, Radovic-Moreno A, Gu FX, Langer RS. Drug delivery system for pharmaceuticals and radiation. 2009.
  163. Farokhzad OC, Jon S, Langer RS. Controlled release polymer nanoparticles containing bound nucleic acid ligand for targeting. 2009.
  164. Farokhzad OC, Alexis F, Kuo T, Pridgen E, Radovic-Moreno AF, Langer RS. Drug delivery system using FC fragments. 2009.
  165. von Andrian UH, Farokhzad OC, Langer RS, Junt T, Moseman A, Zhang L, Basto P, Iannacone M, Alexis F. Vaccine nanotechnology. 2009.
  166. Radovic-Moreno AF, Langer RS, Golomb G, Gao W, Farokhzad OC. PH sensitive biodegradable polymeric particles for drug delivery. 2009.
  167. Bassett EK, Slocum AH, Masiakos PT, Pryor HI, Farokhzad OC, Karp JM. Design of a mechanical clutch-based needle-insertion device. Proc Natl Acad Sci U S A. 2009 Apr 07; 106(14):5540-5. PMID: 19307560.
    Citations: 5     Fields:    Translation:Animals
  168. Alexis F, Zhang L, Radovic-Moreno AF, Gu FX, Basto P, Levy-Nissenbaum E, Chan J, Langer RS, Farokhzad OC. Poly(amino acid) targeting moieties. 2009.
  169. Salvador-Morales C, Gao W, Ghatalia P, Murshed F, Aizu W, Langer R, Farokhzad OC. Multifunctional nanoparticles for prostate cancer therapy. Expert Rev Anticancer Ther. 2009 Feb; 9(2):211-21. PMID: 19192959.
    Citations: 7     Fields:    Translation:HumansAnimals
  170. Farokhzad OC, Langer R. Impact of nanotechnology on drug delivery. ACS Nano. 2009 Jan 27; 3(1):16-20. PMID: 19206243.
    Citations: 497     Fields:    Translation:Humans
  171. Salvador-Morales C, Zhang L, Langer R, Farokhzad OC. Immunocompatibility properties of lipid-polymer hybrid nanoparticles with heterogeneous surface functional groups. Biomaterials. 2009 Apr; 30(12):2231-40. PMID: 19167749.
    Citations: 59     Fields:    Translation:HumansCells
  172. Gu F, Langer R, Farokhzad OC. Formulation/preparation of functionalized nanoparticles for in vivo targeted drug delivery. Methods Mol Biol. 2009; 544:589-98. PMID: 19488725.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  173. Chan JM, Zhang L, Yuet KP, Liao G, Rhee JW, Langer R, Farokhzad OC. PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery. Biomaterials. 2009 Mar; 30(8):1627-34. PMID: 19111339.
    Citations: 135     Fields:    Translation:HumansCells
  174. Farokhzad OC, Alexis F, Kuo TT, Pridgen E, Radovic-Moreno AF, Langer RS. Drug delivery systems using FC fragments. 2008.
  175. Alexis F, Basto P, Levy-Nissenbaum E, Radovic-Moreno AF, Zhang L, Pridgen E, Wang AZ, Marein SL, Westerhof K, Molnar LK, Farokhzad OC. HER-2-targe