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W. Allan Walker, M.D.

Concepts

This page shows the publications W. Walker has written about Humans.
Connection Strength

0.356
  1. The impact of indole-3-lactic acid on immature intestinal innate immunity and development: a transcriptomic analysis. Sci Rep. 2021 04 13; 11(1):8088.
    View in: PubMed
    Score: 0.010
  2. Short-chain fatty acid butyrate, a breast milk metabolite, enhances immature intestinal barrier function genes in response to inflammation in vitro and in vivo. Am J Physiol Gastrointest Liver Physiol. 2021 04 01; 320(4):G521-G530.
    View in: PubMed
    Score: 0.010
  3. Breast Milk and Microbiota in the Premature Gut: A Method of Preventing Necrotizing Enterocolitis. Nestle Nutr Inst Workshop Ser. 2020; 94:103-112.
    View in: PubMed
    Score: 0.009
  4. Summary on Microbiota of Milk and Lactation: Influence on Gut Colonization. Nestle Nutr Inst Workshop Ser. 2020; 94:113-114.
    View in: PubMed
    Score: 0.009
  5. Short chain fatty acids produced by colonizing intestinal commensal bacterial interaction with expressed breast milk are anti-inflammatory in human immature enterocytes. PLoS One. 2020; 15(2):e0229283.
    View in: PubMed
    Score: 0.009
  6. Indole-3-lactic acid, a metabolite of tryptophan, secreted by Bifidobacterium longum subspecies infantis is anti-inflammatory in the immature intestine. Pediatr Res. 2020 08; 88(2):209-217.
    View in: PubMed
    Score: 0.009
  7. The developmentally regulated fetal enterocyte gene, ZP4, mediates anti-inflammation by the symbiotic bacterial surface factor polysaccharide A on Bacteroides fragilis. Am J Physiol Gastrointest Liver Physiol. 2019 10 01; 317(4):G398-G407.
    View in: PubMed
    Score: 0.009
  8. The importance of appropriate initial bacterial colonization of the intestine in newborn, child, and adult health. Pediatr Res. 2017 Sep; 82(3):387-395.
    View in: PubMed
    Score: 0.008
  9. Bacterial Colonization of the Newborn Gut, Immune Development, and Prevention of Disease. Nestle Nutr Inst Workshop Ser. 2017; 88:23-33.
    View in: PubMed
    Score: 0.008
  10. Summary of Evolution of Human Microbiota. Nestle Nutr Inst Workshop Ser. 2017; 88:55-56.
    View in: PubMed
    Score: 0.008
  11. The symbiotic bacterial surface factor polysaccharide A on Bacteroides fragilis inhibits IL-1ß-induced inflammation in human fetal enterocytes via toll receptors 2 and 4. PLoS One. 2017; 12(3):e0172738.
    View in: PubMed
    Score: 0.008
  12. Influence of maternal breast milk ingestion on acquisition of the intestinal microbiome in preterm infants. Microbiome. 2016 12 30; 4(1):68.
    View in: PubMed
    Score: 0.008
  13. Anti-inflammatory effects of Bifidobacterium longum subsp infantis secretions on fetal human enterocytes are mediated by TLR-4 receptors. Am J Physiol Gastrointest Liver Physiol. 2016 10 01; 311(4):G744-G753.
    View in: PubMed
    Score: 0.007
  14. Differential Expression of the Activator Protein 1 Transcription Factor Regulates Interleukin-1ß Induction of Interleukin 6 in the Developing Enterocyte. PLoS One. 2016; 11(1):e0145184.
    View in: PubMed
    Score: 0.007
  15. From Birth to "Immunohealth," Allergies and Enterocolitis. J Clin Gastroenterol. 2015 Nov-Dec; 49 Suppl 1:S7-S12.
    View in: PubMed
    Score: 0.007
  16. Long-chain polyunsaturated fatty acids attenuate the IL-1ß-induced proinflammatory response in human fetal intestinal epithelial cells. Pediatr Res. 2015 Dec; 78(6):626-33.
    View in: PubMed
    Score: 0.007
  17. Why is initial bacterial colonization of the intestine important to infants' and children's health? J Pediatr Gastroenterol Nutr. 2015 Mar; 60(3):294-307.
    View in: PubMed
    Score: 0.007
  18. Toll-like receptor-4 in human and mouse colonic epithelium is developmentally regulated: a possible role in necrotizing enterocolitis. Pediatr Res. 2015 Mar; 77(3):416-24.
    View in: PubMed
    Score: 0.007
  19. Breast milk, microbiota, and intestinal immune homeostasis. Pediatr Res. 2015 Jan; 77(1-2):220-8.
    View in: PubMed
    Score: 0.006
  20. Conditioned medium from Bifidobacteria infantis protects against Cronobacter sakazakii-induced intestinal inflammation in newborn mice. Am J Physiol Gastrointest Liver Physiol. 2014 May 01; 306(9):G779-87.
    View in: PubMed
    Score: 0.006
  21. Initial intestinal colonization in the human infant and immune homeostasis. Ann Nutr Metab. 2013; 63 Suppl 2:8-15.
    View in: PubMed
    Score: 0.006
  22. Current opinion in gastroenterology. Curr Opin Gastroenterol. 2012 Nov; 28(6):547-50.
    View in: PubMed
    Score: 0.006
  23. Treatment of necrotizing enterocolitis with probiotics. Gastroenterol Clin North Am. 2012 Dec; 41(4):733-46.
    View in: PubMed
    Score: 0.006
  24. TGF-ß2 induces maturation of immature human intestinal epithelial cells and inhibits inflammatory cytokine responses induced via the NF-?B pathway. J Pediatr Gastroenterol Nutr. 2012 May; 54(5):630-8.
    View in: PubMed
    Score: 0.005
  25. Early gut colonization and subsequent obesity risk. Curr Opin Clin Nutr Metab Care. 2012 May; 15(3):278-84.
    View in: PubMed
    Score: 0.005
  26. Probiotics in the prevention of necrotizing enterocolitis. J Clin Gastroenterol. 2011 Nov; 45 Suppl:S133-8.
    View in: PubMed
    Score: 0.005
  27. The role of microbes in developmental immunologic programming. Pediatr Res. 2011 Jun; 69(6):465-72.
    View in: PubMed
    Score: 0.005
  28. The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: an immature innate immune response. PLoS One. 2011 Mar 21; 6(3):e17776.
    View in: PubMed
    Score: 0.005
  29. Hydrocortisone induces changes in gene expression and differentiation in immature human enterocytes. Am J Physiol Gastrointest Liver Physiol. 2011 Mar; 300(3):G425-32.
    View in: PubMed
    Score: 0.005
  30. Breast milk-transforming growth factor-ß2 specifically attenuates IL-1ß-induced inflammatory responses in the immature human intestine via an SMAD6- and ERK-dependent mechanism. Neonatology. 2011; 99(3):192-201.
    View in: PubMed
    Score: 0.005
  31. Mead Johnson Symposium: functional proteins in human milk: role in infant health and development. J Pediatr. 2010 Feb; 156(2 Suppl):S1-2.
    View in: PubMed
    Score: 0.005
  32. Breast milk as the gold standard for protective nutrients. J Pediatr. 2010 Feb; 156(2 Suppl):S3-7.
    View in: PubMed
    Score: 0.005
  33. State of research in pediatric gastroenterology, hepatology, and nutrition: 2010 and beyond. Gastroenterology. 2010 Feb; 138(2):411-6, 416.e1-2.
    View in: PubMed
    Score: 0.005
  34. Potential roles and clinical utility of prebiotics in newborns, infants, and children: proceedings from a global prebiotic summit meeting, New York City, June 27-28, 2008. J Pediatr. 2009 Nov; 155(5):S61-70.
    View in: PubMed
    Score: 0.005
  35. ADP-ribosylation factors regulate the development of CT signaling in immature human enterocytes. Am J Physiol Gastrointest Liver Physiol. 2009 Jun; 296(6):G1221-9.
    View in: PubMed
    Score: 0.004
  36. Academy of Breastfeeding Medicine founder's lecture 2008: breastfeeding--an extrauterine link between mother and child. Breastfeed Med. 2009 Mar; 4(1):3-10.
    View in: PubMed
    Score: 0.004
  37. Immunology section. Curr Opin Gastroenterol. 2008 Nov; 24(6):698-700.
    View in: PubMed
    Score: 0.004
  38. Probiotics: role in pathophysiology and prevention in necrotizing enterocolitis. Semin Perinatol. 2008 Apr; 32(2):127-37.
    View in: PubMed
    Score: 0.004
  39. Hydrocortisone modulates cholera toxin endocytosis by regulating immature enterocyte plasma membrane phospholipids. Gastroenterology. 2008 Jul; 135(1):185-193.e1.
    View in: PubMed
    Score: 0.004
  40. Mechanisms of action of probiotics. Clin Infect Dis. 2008 Feb 01; 46 Suppl 2:S87-91; discussion S144-51.
    View in: PubMed
    Score: 0.004
  41. Neonatal microbial flora and disease outcome. Nestle Nutr Workshop Ser Pediatr Program. 2008; 61:211-24.
    View in: PubMed
    Score: 0.004
  42. Intestinal immune health. Nestle Nutr Workshop Ser Pediatr Program. 2008; 62:111-21; discussion 121-5.
    View in: PubMed
    Score: 0.004
  43. Commensal bacteria and epithelial cross talk in the developing intestine. Curr Gastroenterol Rep. 2007 Oct; 9(5):385-92.
    View in: PubMed
    Score: 0.004
  44. Symposium introduction: metabolic syndrome and the onset of cancer. Am J Clin Nutr. 2007 09; 86(3):s817-9.
    View in: PubMed
    Score: 0.004
  45. Secreted probiotic factors ameliorate enteropathogenic infection in zinc-deficient human Caco-2 and T84 cell lines. Pediatr Res. 2007 Aug; 62(2):139-44.
    View in: PubMed
    Score: 0.004
  46. Protection of the neonate by the innate immune system of developing gut and of human milk. Pediatr Res. 2007 Jan; 61(1):2-8.
    View in: PubMed
    Score: 0.004
  47. State of pediatric gastroenterology, hepatology, and nutrition: 2006 and beyond. Gastroenterology. 2007 Jan; 132(1):434-6.
    View in: PubMed
    Score: 0.004
  48. Probiotics and chronic disease. J Clin Gastroenterol. 2006 Mar; 40(3):270-4.
    View in: PubMed
    Score: 0.004
  49. Probiotics as flourishing benefactors for the human body. Gastroenterol Nurs. 2006 Jan-Feb; 29(1):26-34.
    View in: PubMed
    Score: 0.004
  50. Lipopolysaccharide-induced human enterocyte tolerance to cytokine-mediated interleukin-8 production may occur independently of TLR-4/MD-2 signaling. Pediatr Res. 2006 Jan; 59(1):89-95.
    View in: PubMed
    Score: 0.003
  51. Worm therapy for ulcerative colitis: a possible link to regulatory T cells. J Pediatr Gastroenterol Nutr. 2005 Jul; 41(1):139-40.
    View in: PubMed
    Score: 0.003
  52. Science-based solutions to obesity: what are the roles of academia, government, industry, and health care? Am J Clin Nutr. 2005 07; 82(1 Suppl):207S-210S.
    View in: PubMed
    Score: 0.003
  53. Opportunities in pediatric IBD research. J Pediatr Gastroenterol Nutr. 2005 Apr; 40 Suppl 1:S4.
    View in: PubMed
    Score: 0.003
  54. Endocytosis of cholera toxin by human enterocytes is developmentally regulated. Am J Physiol Gastrointest Liver Physiol. 2005 Aug; 289(2):G332-41.
    View in: PubMed
    Score: 0.003
  55. Glucocorticoid responsiveness in developing human intestine: possible role in prevention of necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol. 2005 Jan; 288(1):G85-92.
    View in: PubMed
    Score: 0.003
  56. Symposium introduction: nutrition and gene regulation. J Nutr. 2004 Sep; 134(9):2434S-2436S.
    View in: PubMed
    Score: 0.003
  57. Innate immunity of the gut: mucosal defense in health and disease. J Pediatr Gastroenterol Nutr. 2004 May; 38(5):463-73.
    View in: PubMed
    Score: 0.003
  58. The dynamic effects of breastfeeding on intestinal development and host defense. Adv Exp Med Biol. 2004; 554:155-70.
    View in: PubMed
    Score: 0.003
  59. Development of microbial-human enterocyte interaction: cholera toxin. Pediatr Res. 2003 Aug; 54(2):212-8.
    View in: PubMed
    Score: 0.003
  60. Distribution of the IgG Fc receptor, FcRn, in the human fetal intestine. Pediatr Res. 2003 Feb; 53(2):295-301.
    View in: PubMed
    Score: 0.003
  61. Bacterial-enterocyte crosstalk: cellular mechanisms in health and disease. J Pediatr Gastroenterol Nutr. 2003 Feb; 36(2):175-85.
    View in: PubMed
    Score: 0.003
  62. Innovative teaching strategies for training physicians in clinical nutrition: an overview. J Nutr. 2003 Feb; 133(2):541S-3S.
    View in: PubMed
    Score: 0.003
  63. Normal and glucocorticoid-induced development of the human small intestinal xenograft. Am J Physiol Regul Integr Comp Physiol. 2003 Jul; 285(1):R162-70.
    View in: PubMed
    Score: 0.003
  64. Protective nutrients and functional foods for the gastrointestinal tract. Am J Clin Nutr. 2002 May; 75(5):789-808.
    View in: PubMed
    Score: 0.003
  65. Development of the intestinal mucosal barrier. J Pediatr Gastroenterol Nutr. 2002 May-Jun; 34 Suppl 1:S33-9.
    View in: PubMed
    Score: 0.003
  66. Nutritional impact of pre- and probiotics as protective gastrointestinal organisms. Annu Rev Nutr. 2002; 22:107-38.
    View in: PubMed
    Score: 0.003
  67. Hydrocortisone-induced anti-inflammatory effects in immature human enterocytes depend on the timing of exposure. Am J Physiol Gastrointest Liver Physiol. 2016 06 01; 310(11):G920-9.
    View in: PubMed
    Score: 0.002
  68. Recommendations for Probiotic Use--2015 Update: Proceedings and Consensus Opinion. J Clin Gastroenterol. 2015 Nov-Dec; 49 Suppl 1:S69-73.
    View in: PubMed
    Score: 0.002
  69. Secreted Metabolites of Bifidobacterium infantis and Lactobacillus acidophilus Protect Immature Human Enterocytes from IL-1ß-Induced Inflammation: A Transcription Profiling Analysis. PLoS One. 2015; 10(4):e0124549.
    View in: PubMed
    Score: 0.002
  70. Longitudinal analysis of the premature infant intestinal microbiome prior to necrotizing enterocolitis: a case-control study. PLoS One. 2015; 10(3):e0118632.
    View in: PubMed
    Score: 0.002
  71. Lactobacillus rhamnosus GG and its SpaC pilus adhesin modulate inflammatory responsiveness and TLR-related gene expression in the fetal human gut. Pediatr Res. 2015 Apr; 77(4):528-35.
    View in: PubMed
    Score: 0.002
  72. New insights into probiotic mechanisms: a harvest from functional and metagenomic studies. Gut Microbes. 2013 Mar-Apr; 4(2):94-100.
    View in: PubMed
    Score: 0.001
  73. Probiotics prevent necrotizing enterocolitis by modulating enterocyte genes that regulate innate immune-mediated inflammation. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 15; 304(2):G132-41.
    View in: PubMed
    Score: 0.001
  74. Butyrate regulates the expression of pathogen-triggered IL-8 in intestinal epithelia. Pediatr Res. 2007 Nov; 62(5):542-6.
    View in: PubMed
    Score: 0.001
  75. Cooperative interactions between flagellin and SopE2 in the epithelial interleukin-8 response to Salmonella enterica serovar typhimurium infection. Infect Immun. 2004 Sep; 72(9):5052-62.
    View in: PubMed
    Score: 0.001
  76. Developmentally regulated IkappaB expression in intestinal epithelium and susceptibility to flagellin-induced inflammation. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7404-8.
    View in: PubMed
    Score: 0.001
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.