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Jeffrey Joseph Fredberg, Ph.D.

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Biography
education and training
Tufts University, Medford, MassachusettsBSME1968
Massachusetts Institute of Technology, Cambridge, MassachusettsPhD1973

Overview
overview
Our laboratory seeks to discover physical laws governing the abilities of the cytoskeleton to deform, contract, and remodel. These basic mechanical processes underlie a range of higher level phenomena in health and disease including many aspects of cancer, cardiovascular disease, malaria, and morphogenesis, but our major research emphasis is the role of these processes in airway narrowing in asthma. Trainees with backgrounds in engineering sciences, cell biology, or physics of soft condensed matter learn how to work side-by-side to pose new questions, invent new nanotechnologies, apply these technologies in novel experimental investigations, and analyze resulting data in terms of evolving mechanistic understanding of the physical properties of the living cell.
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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01HL148152 (FREDBERG, JEFFREY J ;PARK, JIN-AH) Aug 15, 2019 - Apr 30, 2024
    NIH
    Physics of bronchial epithelial unjamming
    Role: Principal Investigator
  2. U01CA202123 (FREDBERG, JEFFREY J) Sep 23, 2015 - Aug 31, 2020
    NIH
    Epithelial layer jamming in breast cancer cell migration
    Role: Principal Investigator
  3. P01HL120839 (FREDBERG, JEFFREY J) Aug 1, 2014 - Dec 31, 2019
    NIH
    Physics of collective cellular migration in lung health and disease
    Role: Principal Investigator
  4. P50HL107171 (SOLWAY, JULIAN) May 1, 2011 - Apr 30, 2014
    NIH
    Therapeutic Potentiation of Bronchial Dilatation
    Role: Principal Investigator
  5. R01HL107561 (FREDBERG, JEFFREY J) Apr 6, 2011 - Mar 31, 2018
    NIH
    Mechanics of Monolayer Migration
    Role: Principal Investigator

Bibliographic
selected publications
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© 2023 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.