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Jeffrey Joseph Fredberg, Ph.D.

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Biography
Tufts University, Medford, MassachusettsBSME1968
Massachusetts Institute of Technology, Cambridge, MassachusettsPhD1973

Overview
Our laboratory seeks to discover physical laws governing the abilities of the cytoskeleton to deform, contract, and remodel. These basic mechanical processes underlie a range of higher level phenomena in health and disease including many aspects of cancer, cardiovascular disease, malaria, and morphogenesis, but our major research emphasis is the role of these processes in airway narrowing in asthma. Trainees with backgrounds in engineering sciences, cell biology, or physics of soft condensed matter learn how to work side-by-side to pose new questions, invent new nanotechnologies, apply these technologies in novel experimental investigations, and analyze resulting data in terms of evolving mechanistic understanding of the physical properties of the living cell.

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL148152 (FREDBERG, JEFFREY J) Aug 15, 2019 - Apr 30, 2023
    NIH
    Physics of bronchial epithelial unjamming
    Role: Principal Investigator
  2. U01CA202123 (FREDBERG, JEFFREY J) Sep 23, 2015 - Aug 31, 2020
    NIH
    Epithelial layer jamming in breast cancer cell migration
    Role: Principal Investigator
  3. P01HL120839 (FREDBERG, JEFFREY J) Aug 1, 2014 - Dec 31, 2019
    NIH
    Physics of collective cellular migration in lung health and disease
    Role: Principal Investigator
  4. P50HL107171 (SOLWAY, JULIAN) May 1, 2011 - Apr 30, 2014
    NIH
    Therapeutic Potentiation of Bronchial Dilatation
    Role: Principal Investigator
  5. R01HL107561 (FREDBERG, JEFFREY J) Apr 6, 2011 - Mar 31, 2018
    NIH
    Mechanics of Monolayer Migration
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Fredberg JJ. On the origins of order. Soft Matter. 2022 Mar 23; 18(12):2346-2353. PMID: 35244652.
    Citations:    Fields:    
  2. Wu H, Shen Y, Sivagurunathan S, Weber MS, Adam SA, Shin JH, Fredberg JJ, Medalia O, Goldman R, Weitz DA. Vimentin intermediate filaments and filamentous actin form unexpected interpenetrating networks that redefine the cell cortex. Proc Natl Acad Sci U S A. 2022 03 08; 119(10):e2115217119. PMID: 35235449.
    Citations:    Fields:    
  3. Mwase C, Phung TN, O'Sullivan MJ, Mitchel JA, De Marzio M, Kiliç A, Weiss ST, Fredberg JJ, Park JA. Mechanical Compression of Human Airway Epithelial Cells Induces Release of Extracellular Vesicles Containing Tenascin C. Cells. 2022 01 13; 11(2). PMID: 35053372.
    Citations:    Fields:    Translation:HumansCells
  4. Kang W, Ferruzzi J, Spatarelu CP, Han YL, Sharma Y, Koehler SA, Mitchel JA, Khan A, Butler JP, Roblyer D, Zaman MH, Park JA, Guo M, Chen Z, Pegoraro AF, Fredberg JJ. A novel jamming phase diagram links tumor invasion to non-equilibrium phase separation. iScience. 2021 Nov 19; 24(11):103252. PMID: 34755092.
    Citations: 2     
  5. Mohammed D, Park CY, Fredberg JJ, Weitz DA. Tumorigenic mesenchymal clusters are less sensitive to moderate osmotic stresses due to low amounts of junctional E-cadherin. Sci Rep. 2021 08 11; 11(1):16279. PMID: 34381087.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  6. Atia L, Fredberg JJ, Gov NS, Pegoraro AF. Are cell jamming and unjamming essential in tissue development? Cells Dev. 2021 Aug 04; 203727. PMID: 34363993.
    Citations: 2     Fields:    
  7. De Marzio M, Kiliç A, Maiorino E, Mitchel JA, Mwase C, O'Sullivan MJ, McGill M, Chase R, Fredberg JJ, Park JA, Glass K, Weiss ST. Genomic signatures of the unjamming transition in compressed human bronchial epithelial cells. Sci Adv. 2021 07; 7(30). PMID: 34301595.
    Citations: 4     Fields:    
  8. Berger KI, Adam O, Dal Negro RW, Kaminsky DA, Shiner RJ, Burgos F, de Jongh FHC, Cohen I, Fredberg JJ. Validation of a Novel Compact System for the Measurement of Lung Volumes. Chest. 2021 06; 159(6):2356-2365. PMID: 33539839.
    Citations: 2     Fields:    Translation:Humans
  9. DeCamp SJ, Tsuda VMK, Ferruzzi J, Koehler SA, Giblin JT, Roblyer D, Zaman MH, Weiss ST, Kiliç A, De Marzio M, Park CY, Ogassavara NC, Mitchel JA, Butler JP, Fredberg JJ. Epithelial layer unjamming shifts energy metabolism toward glycolysis. Sci Rep. 2020 10 27; 10(1):18302. PMID: 33110128.
    Citations: 8     Fields:    Translation:AnimalsCells
  10. Mitchel JA, Das A, O'Sullivan MJ, Stancil IT, DeCamp SJ, Koehler S, Ocaña OH, Butler JP, Fredberg JJ, Nieto MA, Bi D, Park JA. In primary airway epithelial cells, the unjamming transition is distinct from the epithelial-to-mesenchymal transition. Nat Commun. 2020 10 07; 11(1):5053. PMID: 33028821.
    Citations: 24     Fields:    Translation:HumansCells
  11. Charrier EE, Pogoda K, Li R, Park CY, Fredberg JJ, Janmey PA. A novel method to make viscoelastic polyacrylamide gels for cell culture and traction force microscopy. APL Bioeng. 2020 Sep; 4(3):036104. PMID: 32666015.
    Citations: 5     
  12. Green Y, Fredberg JJ, Butler JP. Relationship between velocities, tractions, and intercellular stresses in the migrating epithelial monolayer. Phys Rev E. 2020 Jun; 101(6-1):062405. PMID: 32688543.
    Citations:    Fields:    Translation:Cells
  13. Kiliç A, Ameli A, Park JA, Kho AT, Tantisira K, Santolini M, Cheng F, Mitchel JA, McGill M, O'Sullivan MJ, De Marzio M, Sharma A, Randell SH, Drazen JM, Fredberg JJ, Weiss ST. Mechanical forces induce an asthma gene signature in healthy airway epithelial cells. Sci Rep. 2020 01 22; 10(1):966. PMID: 31969610.
    Citations: 15     Fields:    Translation:HumansCells
  14. He S, Green Y, Saeidi N, Li X, Fredberg JJ, Ji B, Pismen LM. A theoretical model of collective cell polarization and alignment. J Mech Phys Solids. 2020 Apr; 137. PMID: 33518805.
    Citations: 3     
  15. Gazzola M, Henry C, Lortie K, Khadangi F, Park CY, Fredberg JJ, Bossé Y. Airway smooth muscle tone increases actin filamentogenesis and contractile capacity. Am J Physiol Lung Cell Mol Physiol. 2020 02 01; 318(2):L442-L451. PMID: 31850799.
    Citations:    Fields:    Translation:HumansAnimalsCells
  16. Kim JH, Pegoraro AF, Das A, Koehler SA, Ujwary SA, Lan B, Mitchel JA, Atia L, He S, Wang K, Bi D, Zaman MH, Park JA, Butler JP, Lee KH, Starr JR, Fredberg JJ. Unjamming and collective migration in MCF10A breast cancer cell lines. Biochem Biophys Res Commun. 2020 01 15; 521(3):706-715. PMID: 31699371.
    Citations: 10     Fields:    Translation:HumansCells
  17. Han YL, Pegoraro AF, Li H, Li K, Yuan Y, Xu G, Gu Z, Sun J, Hao Y, Gupta SK, Li Y, Tang W, Tang X, Teng L, Fredberg JJ, Guo M. Cell swelling, softening and invasion in a three-dimensional breast cancer model. Nat Phys. 2020 Jan; 16(1):101-108. PMID: 32905405.
    Citations: 39     
  18. Jang H, Kim J, Shin JH, Fredberg JJ, Park CY, Park Y. Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration. J Vis Exp. 2019 10 13; (152). PMID: 31657799.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  19. Patel G, Xu N, Nguyen A, Alvarez DF, Fredberg JJ, Stevens T, Tambe DT. Mechanical signaling in a pulmonary microvascular endothelial cell monolayer. Biochem Biophys Res Commun. 2019 11 05; 519(2):337-343. PMID: 31514994.
    Citations: 2     Fields:    Translation:AnimalsCells
  20. Reed EB, Ard S, La J, Park CY, Culligan L, Fredberg JJ, Smolyaninova LV, Orlov SN, Chen B, Guzy R, Mutlu GM, Dulin NO. Anti-fibrotic effects of tannic acid through regulation of a sustained TGF-beta receptor signaling. Respir Res. 2019 Jul 29; 20(1):168. PMID: 31358001.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  21. Jang H, Kim J, Shin JH, Fredberg JJ, Park CY, Park Y. Traction microscopy with integrated microfluidics: responses of the multi-cellular island to gradients of HGF. Lab Chip. 2019 04 23; 19(9):1579-1588. PMID: 30924490.
    Citations: 4     Fields:    Translation:AnimalsCells
  22. Mandal K, Aroush DR, Graber ZT, Wu B, Park CY, Fredberg JJ, Guo W, Baumgart T, Janmey PA. Correction to Soft Hyaluronic Gels Promote Cell Spreading, Stress Fibers, Focal Adhesion, and Membrane Tension by Phosphoinositide Signaling, Not Traction Force. ACS Nano. 2019 Apr 23; 13(4):4854. PMID: 30883087.
    Citations:    Fields:    
  23. He S, Carman CV, Lee JH, Lan B, Koehler S, Atia L, Park CY, Kim JH, Mitchel JA, Park JA, Butler JP, Lu Q, Fredberg JJ. The tumor suppressor p53 can promote collective cellular migration. PLoS One. 2019; 14(2):e0202065. PMID: 30707705.
    Citations: 4     Fields:    Translation:HumansCells
  24. Vahabikashi A, Park CY, Perkumas K, Zhang Z, Deurloo EK, Wu H, Weitz DA, Stamer WD, Goldman RD, Fredberg JJ, Johnson M. Probe Sensitivity to Cortical versus Intracellular Cytoskeletal Network Stiffness. Biophys J. 2019 02 05; 116(3):518-529. PMID: 30685055.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  25. Mandal K, Raz-Ben Aroush D, Graber ZT, Wu B, Park CY, Fredberg JJ, Guo W, Baumgart T, Janmey PA. Soft Hyaluronic Gels Promote Cell Spreading, Stress Fibers, Focal Adhesion, and Membrane Tension by Phosphoinositide Signaling, Not Traction Force. ACS Nano. 2019 01 22; 13(1):203-214. PMID: 30500159.
    Citations: 17     Fields:    Translation:HumansCells
  26. Atia L, Bi D, Sharma Y, Mitchel JA, Gweon B, Koehler S, DeCamp SJ, Lan B, Kim JH, Hirsch R, Pegoraro AF, Lee KH, Starr JR, Weitz DA, Martin AC, Park JA, Butler JP, Fredberg JJ. Geometric constraints during epithelial jamming. Nat Phys. 2018 Jun; 14:613-620. PMID: 30151030.
    Citations: 43     
  27. Sharma Y, Atia L, Rhodes CS, DeCamp SJ, Mitchel J, Fredberg JJ. Scaling Physiologic Function from Cell to Tissue in Asthma, Cancer, and Development. Ann Am Thorac Soc. 2018 02; 15(Suppl 1):S35-S37. PMID: 29461895.
    Citations:    Fields:    Translation:Humans
  28. Lan B, Krishnan R, Park CY, Watanabe RA, Panganiban R, Butler JP, Lu Q, Cole WC, Fredberg JJ. Transient stretch induces cytoskeletal fluidization through the severing action of cofilin. Am J Physiol Lung Cell Mol Physiol. 2018 05 01; 314(5):L799-L807. PMID: 29345194.
    Citations: 10     Fields:    Translation:HumansCells
  29. Bhatawadekar SA, Keller G, Francisco CO, Inman MD, Fredberg JJ, Tarlo SM, Stanbrook M, Lyons OD, Yadollahi A. Reduced Baseline Airway Caliber Relates to Larger Airway Sensitivity to Rostral Fluid Shift in Asthma. Front Physiol. 2017; 8:1012. PMID: 29311954.
    Citations: 3     
  30. O'Sullivan MJ, Gabriel E, Panariti A, Park CY, Ijpma G, Fredberg JJ, Lauzon AM, Martin JG. Epithelial Cells Induce a Cyclo-Oxygenase-1-Dependent Endogenous Reduction in Airway Smooth Muscle Contractile Phenotype. Am J Respir Cell Mol Biol. 2017 12; 57(6):683-691. PMID: 28708434.
    Citations: 4     Fields:    Translation:HumansCells
  31. Hardin CC, Chattoraj J, Manomohan G, Colombo J, Nguyen T, Tambe D, Fredberg JJ, Birukov K, Butler JP, Del Gado E, Krishnan R. Long-range stress transmission guides endothelial gap formation. Biochem Biophys Res Commun. 2018 01 01; 495(1):749-754. PMID: 29137986.
    Citations: 8     Fields:    Translation:HumansCells
  32. Lee G, Atia L, Lan B, Sharma Y, Nissim L, Wu MR, Pery E, Lu TK, Park CY, Butler JP, Fredberg JJ. Contact guidance and collective migration in the advancing epithelial monolayer. Connect Tissue Res. 2018 07; 59(4):309-315. PMID: 28945485.
    Citations: 4     Fields:    Translation:AnimalsCells
  33. Guo M, Pegoraro AF, Mao A, Zhou EH, Arany PR, Han Y, Burnette DT, Jensen MH, Kasza KE, Moore JR, Mackintosh FC, Fredberg JJ, Mooney DJ, Lippincott-Schwartz J, Weitz DA. Cell volume change through water efflux impacts cell stiffness and stem cell fate. Proc Natl Acad Sci U S A. 2017 10 10; 114(41):E8618-E8627. PMID: 28973866.
    Citations: 113     Fields:    Translation:AnimalsCells
  34. Rodríguez-Franco P, Brugués A, Marín-Llauradó A, Conte V, Solanas G, Batlle E, Fredberg JJ, Roca-Cusachs P, Sunyer R, Trepat X. Long-lived force patterns and deformation waves at repulsive epithelial boundaries. Nat Mater. 2017 10; 16(10):1029-1037. PMID: 28892054.
    Citations: 16     Fields:    Translation:AnimalsCells
  35. Jang H, Notbohm J, Gweon B, Cho Y, Park CY, Kee SH, Fredberg JJ, Shin JH, Park Y. Homogenizing cellular tension by hepatocyte growth factor in expanding epithelial monolayer. Sci Rep. 2017 04 04; 8:45844. PMID: 28374776.
    Citations: 11     Fields:    Translation:AnimalsCells
  36. Rosner SR, Pascoe CD, Blankman E, Jensen CC, Krishnan R, James AL, Elliot JG, Green FH, Liu JC, Seow CY, Park JA, Beckerle MC, Paré PD, Fredberg JJ, Smith MA. The actin regulator zyxin reinforces airway smooth muscle and accumulates in airways of fatal asthmatics. PLoS One. 2017; 12(3):e0171728. PMID: 28278518.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  37. Hiorns JE, Bidan CM, Jensen OE, Gosens R, Kistemaker LE, Fredberg JJ, Butler JP, Krishnan R, Brook BS. Corrigendum: Airway and Parenchymal Strains during Bronchoconstriction in the Precision Cut Lung Slice. Front Physiol. 2017; 8:117. PMID: 28261114.
    Citations:    
  38. Bhatawadekar SA, Inman MD, Fredberg JJ, Tarlo SM, Lyons OD, Keller G, Yadollahi A. Contribution of rostral fluid shift to intrathoracic airway narrowing in asthma. J Appl Physiol (1985). 2017 Apr 01; 122(4):809-816. PMID: 28082337.
    Citations: 5     Fields:    Translation:Humans
  39. Alencar AM, Ferraz MS, Park CY, Millet E, Trepat X, Fredberg JJ, Butler JP. Non-equilibrium cytoquake dynamics in cytoskeletal remodeling and stabilization. Soft Matter. 2016 Oct 19; 12(41):8506-8511. PMID: 27722665.
    Citations: 4     Fields:    Translation:HumansCells
  40. Park JA, Atia L, Mitchel JA, Fredberg JJ, Butler JP. Collective migration and cell jamming in asthma, cancer and development. J Cell Sci. 2016 09 15; 129(18):3375-83. PMID: 27550520.
    Citations: 43     Fields:    Translation:HumansAnimals
  41. Hiorns JE, Bidan CM, Jensen OE, Gosens R, Kistemaker LE, Fredberg JJ, Butler JP, Krishnan R, Brook BS. Airway and Parenchymal Strains during Bronchoconstriction in the Precision Cut Lung Slice. Front Physiol. 2016; 7:309. PMID: 27559314.
    Citations: 11     
  42. Notbohm J, Banerjee S, Utuje KJC, Gweon B, Jang H, Park Y, Shin J, Butler JP, Fredberg JJ, Marchetti MC. Cellular Contraction and Polarization Drive Collective Cellular Motion. Biophys J. 2016 Jun 21; 110(12):2729-2738. PMID: 27332131.
    Citations: 36     Fields:    Translation:AnimalsCells
  43. Faiz A, Donovan C, Nieuwenhuis MA, van den Berge M, Postma DS, Yao S, Park CY, Hirsch R, Fredberg JJ, Tjin G, Halayko AJ, Rempel KL, Ward JP, Lee T, Bossé Y, Nickle DC, Obeidat M, Vonk JM, Black JL, Oliver BG, Krishnan R, McParland B, Bourke JE, Burgess JK. Latrophilin receptors: novel bronchodilator targets in asthma. Thorax. 2017 01; 72(1):74-82. PMID: 27325752.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  44. Gazzola M, Henry C, Couture C, Marsolais D, King GG, Fredberg JJ, Bossé Y. Smooth muscle in human bronchi is disposed to resist airway distension. Respir Physiol Neurobiol. 2016 07 15; 229:51-8. PMID: 27095271.
    Citations: 4     Fields:    Translation:Humans
  45. Park JA, Mitchel JA, Qazvini NT, Kim JH, Park CY, Butler JP, Israel E, Randell SH, Shore SA, Drazen JM, Fredberg JJ. Compressive Stress Causes an Unjamming Transition and an Epithelial-Mesenchymal Transition in the Airway Epithelium in Asthma. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S102. PMID: 27027941.
    Citations: 2     Fields:    
  46. Park JA, Fredberg JJ. Cell Jamming in the Airway Epithelium. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S64-7. PMID: 27027955.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  47. Wang K, Cai LH, Lan B, Fredberg JJ. Hidden in the mist no more: physical force in cell biology. Nat Methods. 2016 Feb; 13(2):124-5. PMID: 26820546.
    Citations: 8     Fields:    Translation:Humans
  48. Pegoraro AF, Fredberg JJ, Park JA. Problems in biology with many scales of length: Cell-cell adhesion and cell jamming in collective cellular migration. Exp Cell Res. 2016 04 10; 343(1):54-59. PMID: 26546401.
    Citations: 11     Fields:    Translation:HumansAnimals
  49. Fredberg J, Sedwick C. Jeffrey Fredberg: Flow under pressure. J Cell Biol. 2015 Sep 14; 210(6):868-9. PMID: 26370495.
    Citations:    Fields:    Translation:HumansAnimals
  50. Tambe DT, Fredberg JJ. And I hope you like jamming too. New J Phys. 2015 Sep; 17(9). PMID: 27594802.
    Citations: 5     
  51. Park JA, Kim JH, Bi D, Mitchel JA, Qazvini NT, Tantisira K, Park CY, McGill M, Kim SH, Gweon B, Notbohm J, Steward R, Burger S, Randell SH, Kho AT, Tambe DT, Hardin C, Shore SA, Israel E, Weitz DA, Tschumperlin DJ, Henske EP, Weiss ST, Manning ML, Butler JP, Drazen JM, Fredberg JJ. Unjamming and cell shape in the asthmatic airway epithelium. Nat Mater. 2015 Oct; 14(10):1040-8. PMID: 26237129.
    Citations: 128     Fields:    Translation:HumansCells
  52. Park JA, Fredberg JJ, Drazen JM. Putting the Squeeze on Airway Epithelia. Physiology (Bethesda). 2015 Jul; 30(4):293-303. PMID: 26136543.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  53. Park CY, Zhou EH, Tambe D, Chen B, Lavoie T, Dowell M, Simeonov A, Maloney DJ, Marinkovic A, Tschumperlin DJ, Burger S, Frykenberg M, Butler JP, Stamer WD, Johnson M, Solway J, Fredberg JJ, Krishnan R. High-throughput screening for modulators of cellular contractile force. Integr Biol (Camb). 2015 Oct; 7(10):1318-24. PMID: 25953078.
    Citations: 29     Fields:    Translation:HumansCells
  54. Steward R, Tambe D, Hardin CC, Krishnan R, Fredberg JJ. Fluid shear, intercellular stress, and endothelial cell alignment. Am J Physiol Cell Physiol. 2015 Apr 15; 308(8):C657-64. PMID: 25652451.
    Citations: 29     Fields:    Translation:HumansCells
  55. Chen C, Xie J, Rajappa R, Deng L, Fredberg J, Yang L. Interleukin-1ß and tumor necrosis factor-a increase stiffness and impair contractile function of articular chondrocytes. Acta Biochim Biophys Sin (Shanghai). 2015 Feb; 47(2):121-9. PMID: 25520178.
    Citations: 23     Fields:    Translation:AnimalsCells
  56. Zhou EH, Watson C, Pizzo R, Cohen J, Dang Q, Ferreira de Barros PM, Park CY, Chen C, Brain JD, Butler JP, Ruberti JW, Fredberg JJ, Demokritou P. Assessing the impact of engineered nanoparticles on wound healing using a novel in vitro bioassay. Nanomedicine (Lond). 2014 Dec; 9(18):2803-15. PMID: 24823434.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  57. Stamer WD, Braakman ST, Zhou EH, Ethier CR, Fredberg JJ, Overby DR, Johnson M. Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction. Prog Retin Eye Res. 2015 Jan; 44:86-98. PMID: 25223880.
    Citations: 61     Fields:    Translation:HumansCells
  58. Mathai JC, Zhou EH, Yu W, Kim JH, Zhou G, Liao Y, Sun TT, Fredberg JJ, Zeidel ML. Hypercompliant apical membranes of bladder umbrella cells. Biophys J. 2014 Sep 16; 107(6):1273-9. PMID: 25229135.
    Citations: 7     Fields:    Translation:AnimalsCells
  59. Overby DR, Zhou EH, Vargas-Pinto R, Pedrigi RM, Fuchshofer R, Braakman ST, Gupta R, Perkumas KM, Sherwood JM, Vahabikashi A, Dang Q, Kim JH, Ethier CR, Stamer WD, Fredberg JJ, Johnson M. Altered mechanobiology of Schlemm's canal endothelial cells in glaucoma. Proc Natl Acad Sci U S A. 2014 Sep 23; 111(38):13876-81. PMID: 25201985.
    Citations: 69     Fields:    Translation:HumansCells
  60. Tambe DT, Butler JP, Fredberg JJ. Comment on "Intracellular stresses in patterned cell assemblies" by M. Moussus et al., Soft Matter, 2014, 10, 2414. Soft Matter. 2014 Oct 21; 10(39):7681-2. PMID: 25186230.
    Citations: 1     Fields:    Translation:HumansCells
  61. Fredberg JJ. Power steering, power brakes, and jamming: evolution of collective cell-cell interactions. Physiology (Bethesda). 2014 Jul; 29(4):218-9. PMID: 24985324.
    Citations: 10     Fields:    Translation:AnimalsCells
  62. Rosner SR, Ram-Mohan S, Paez-Cortez JR, Lavoie TL, Dowell ML, Yuan L, Ai X, Fine A, Aird WC, Solway J, Fredberg JJ, Krishnan R. Airway contractility in the precision-cut lung slice after cryopreservation. Am J Respir Cell Mol Biol. 2014 May; 50(5):876-81. PMID: 24313705.
    Citations: 21     Fields:    Translation:AnimalsCells
  63. Sadati M, Nourhani A, Fredberg JJ, Taheri Qazvini N. Glass-like dynamics in the cell and in cellular collectives. Wiley Interdiscip Rev Syst Biol Med. 2014 Mar-Apr; 6(2):137-49. PMID: 24431332.
    Citations: 13     Fields:    Translation:HumansCells
  64. Coughlin MF, Fredberg JJ. Changes in cytoskeletal dynamics and nonlinear rheology with metastatic ability in cancer cell lines. Phys Biol. 2013 Dec; 10(6):065001. PMID: 24304722.
    Citations: 4     Fields:    Translation:HumansCells
  65. Sieck GC, Hunter P, Fredberg J, Notbohm J. Physiology's impact: Applying mathematics and advanced technologies. Physiology (Bethesda). 2013 Nov; 28(6):363-5. PMID: 24186929.
    Citations:    Fields:    Translation:HumansAnimalsCells
  66. Guo M, Ehrlicher AJ, Mahammad S, Fabich H, Jensen MH, Moore JR, Fredberg JJ, Goldman RD, Weitz DA. The role of vimentin intermediate filaments in cortical and cytoplasmic mechanics. Biophys J. 2013 Oct 01; 105(7):1562-8. PMID: 24094397.
    Citations: 106     Fields:    Translation:AnimalsCells
  67. Kim JH, Serra-Picamal X, Tambe DT, Zhou EH, Park CY, Sadati M, Park JA, Krishnan R, Gweon B, Millet E, Butler JP, Trepat X, Fredberg JJ. Propulsion and navigation within the advancing monolayer sheet. Nat Mater. 2013 Sep; 12(9):856-63. PMID: 23793160.
    Citations: 81     Fields:    Translation:AnimalsCells
  68. Sadati M, Taheri Qazvini N, Krishnan R, Park CY, Fredberg JJ. Collective migration and cell jamming. Differentiation. 2013 Oct; 86(3):121-5. PMID: 23791490.
    Citations: 73     Fields:    Translation:HumansAnimalsCells
  69. Hardin C, Rajendran K, Manomohan G, Tambe DT, Butler JP, Fredberg JJ, Martinelli R, Carman CV, Krishnan R. Glassy dynamics, cell mechanics, and endothelial permeability. J Phys Chem B. 2013 Oct 24; 117(42):12850-6. PMID: 23638866.
    Citations: 10     Fields:    Translation:HumansCells
  70. Steward RL, Rosner SR, Zhou EH, Fredberg JJ. Illuminating human health through cell mechanics. Swiss Med Wkly. 2013; 143:w13766. PMID: 23519500.
    Citations: 2     Fields:    Translation:Humans
  71. Zhou EH, Martinez FD, Fredberg JJ. Cell rheology: mush rather than machine. Nat Mater. 2013 Mar; 12(3):184-5. PMID: 23422717.
    Citations: 7     Fields:    Translation:Cells
  72. Tambe DT, Croutelle U, Trepat X, Park CY, Kim JH, Millet E, Butler JP, Fredberg JJ. Monolayer stress microscopy: limitations, artifacts, and accuracy of recovered intercellular stresses. PLoS One. 2013; 8(2):e55172. PMID: 23468843.
    Citations: 66     Fields: