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Brenner, Michael
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Michael Barry Brenner, M.D.
Title
Elizabeth Fay Brigham Professor Professor of Medicine
Institution
Brigham and Women's Hospital
Department
Medicine
Address
Hale Building for Transformative Medicine
6th Floor, Room 6002Q
60 Fenwood Road
Boston MA 02115
Phone
617/525-1000
Fax
617/525-1010
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research activities and funding
|
selected publications
|
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
P01AI148102
(BRENNER, MICHAEL B.)
Jun 15, 2021 - Mar 31, 2026
NIH
Differentiation of immune cells and fibrobalsts in inflamed tissue in RA and SLE
Role: Principal Investigator
R01AR073833
(BRENNER, MICHAEL B.)
Aug 1, 2019 - Jul 31, 2024
NIH
Deciphering Pathways Driving Inflammatory Fibroblast Effector Functions in RA
Role: Principal Investigator
R21AI144139
(BRENNER, MICHAEL B.)
Feb 20, 2019 - Jan 31, 2021
NIH
iNKT cells hyperactivate DCs
Role: Principal Investigator
R01AR073290
(BRENNER, MICHAEL B.)
Sep 13, 2018 - Jun 30, 2023
NIH
Newly Identified T Peripheral Helper (Tph) Cells in Rheumatoid Arthritis
Role: Principal Investigator
R01AR063709
(BRENNER, MICHAEL B.)
Feb 1, 2015 - Aug 31, 2026
NIH
Cadherin 11 Regulates Synovial Inflammation in Arthritis
Role: Principal Investigator
UH2AR067677
(RAYCHAUDHURI, SOUMYA)
Sep 24, 2014 - May 31, 2021
NIH
RA-SLE Molecular Deconstruction Leadership Center
Role: Principal Investigator
UH2AR067694
(GREGERSEN, PETER K.)
Sep 24, 2014 - May 31, 2021
NIH
Molecular and Cellular Dissection of Early Rheumatoid Arthritis
Role: Co-Principal Investigator
R01AI113046
(BRENNER, MICHAEL B.)
Aug 15, 2014 - May 31, 2024
NIH
Regulatory iNKT Cells Suppress Inflammation and Drive Thermogenesis
Role: Principal Investigator
U01GM092691
(RAYCHAUDHURI, SOUMYA)
Jul 1, 2010 - Jun 30, 2017
NIH
Genetic predictors of response to anti-TNF therapy in rheumatoid arthritis
Role: Principal Investigator
R01AR057382
(BRENNER, MICHAEL B.)
Apr 15, 2010 - Mar 31, 2015
NIH
Regulation of synovial fibroblast function via Cadherin-11 cleavage
Role: Principal Investigator
R01AR056768
(BRENNER, MICHAEL B)
May 15, 2009 - Apr 30, 2014
NIH
Dissection of two rheumatoid arthritis risk loci from genome-wide studies
Role: Principal Investigator
P01AI065858
(ANDERSON, PAUL J.)
Sep 1, 2006 - Aug 31, 2012
NIH
Cellular and Molecular Effectors of Synovitis
Role: Co-Principal Investigator
R01AI063428
(BRENNER, MICHAEL B.)
Dec 1, 2004 - Feb 29, 2016
NIH
CD1d and NKT Cell Activation and Function in Infection
Role: Principal Investigator
R56AI063428
(BRENNER, MICHAEL B)
Dec 1, 2004 - Jul 31, 2011
NIH
CD1d and NKT Cell Activation and Function in Infection
Role: Principal Investigator
R01AR048114
(BRENNER, MICHAEL B)
Jul 1, 2002 - Jun 30, 2013
NIH
Synovial Cadherin in Rheumatoid Arthritis
Role: Principal Investigator
R01AI048932
(BRENNER, MICHAEL B)
May 1, 2000 - Apr 30, 2005
NIH
CD1 IMMUNE RESPONSES AND VACCINES IN ANIMAL MODELS OF TB
Role: Principal Investigator
R13AR045568
(BRENNER, MICHAEL B)
Sep 15, 1998 - Sep 14, 1999
NIH
ANTIGEN PRESENTATION AND AUTOIMMUNE DISEASE MEETING
Role: Principal Investigator
P41RR010888
(COSTELLO, CATHERINE E.)
Jul 1, 1996 - Aug 9, 2012
NIH/NCRR
MASS SPECTROMETRY RESOURCE FOR BIOLOGY AND MEDICINE
Role: Co-Principal Investigator
R01AI038578
(BRENNER, MICHAEL B)
Jun 1, 1995 - Feb 28, 2006
NIH
ROLE OF INTEGRIN ALPHA E BETA 7 IN IMMUNE RESPONSES
Role: Principal Investigator
R01AR043662
(BRENNER, MICHAEL B)
May 6, 1995 - Jun 30, 1999
NIH
ROLE OF A CHAPERONE IN MHC CLASS I ASSEMBLY
Role: Principal Investigator
R01AI028973
(BRENNER, MICHAEL B.)
Dec 1, 1989 - Jun 30, 2015
NIH
Pathways of Antigen Presentation by CD1
Role: Principal Investigator
R37AI028973
(BRENNER, MICHAEL B)
Dec 1, 1989 - Apr 30, 2005
NIH
T LYMPHOCYTE RECOGNITION
Role: Principal Investigator
R01AR039582
(BRENNER, MICHAEL B)
Jul 1, 1988 - Jun 30, 1996
NIH
T-CELLS AND DISEASES
Role: Principal Investigator
R01CA047724
(BRENNER, MICHAEL B)
May 1, 1988 - May 31, 2003
NIH
T CELL RECEPTOR GAMMA/DELTA
Role: Principal Investigator
K08AR001598
(BRENNER, MICHAEL B)
Jul 1, 1986 - Jun 30, 1991
NIH
T CELL RECEPTOR--SPATIAL ARRANGING &ANTIGENIC EPITOPES
Role: Principal Investigator
T32AR007530
(GRAVALLESE, ELLEN M)
Jul 1, 1985 - Apr 30, 2025
NIH
Immunologic Mechanisms and Rheumatic Diseases
Role: Principal Investigator
P60AR036308
(LIANG, MATTHEW H.)
Apr 1, 1985 - Mar 31, 2001
NIH
MULTIPURPOSE ARTHRITIS &MUSCULOSKELETAL DISEASES CENTER
Role: Co-Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Kane H, LaMarche NM, Ní Scannail Á, Garza AE,
Koay HF
, Azad AI,
Kunkemoeller B
, Stevens B,
Brenner MB
,
Lynch L
. Longitudinal analysis of invariant natural killer T cell activation reveals a cMAF-associated transcriptional state of NKT10 cells. Elife. 2022 12 02; 11.
PMID:
36458691
; PMCID:
PMC9831610
.
Citations:
Fields:
Bio
Biology
Translation:
Humans
Animals
Cells
Jonsson AH
, Zhang F, Dunlap G, Gomez-Rivas E, Watts GFM, Faust HJ, Rupani KV, Mears JR, Meednu N, Wang R, Keras G,
Coblyn JS
,
Massarotti EM
,
Todd DJ
, Anolik JH, McDavid A,
Wei K
,
Rao DA
,
Raychaudhuri S
,
Brenner MB
. Granzyme K+ CD8 T cells form a core population in inflamed human tissue. Sci Transl Med. 2022 06 15; 14(649):eabo0686.
PMID:
35704599
; PMCID:
PMC9972878
.
Citations:
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Cells
Korsunsky I
,
Wei K
, Pohin M,
Kim EY
, Barone F, Major T, Taylor E, Ravindran R, Kemble S, Watts GFM,
Jonsson AH
,
Jeong Y
, Athar H, Windell D, Kang JB, Friedrich M, Turner J, Nayar S, Fisher BA, Raza K, Marshall JL, Croft AP,
Tamura T
,
Sholl LM
,
Vivero M
, Rosas IO, Bowman SJ, Coles M, Frei AP, Lassen K, Filer A, Powrie F, Buckley CD,
Brenner MB
,
Raychaudhuri S
. Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases. Med (N Y). 2022 07 08; 3(7):481-518.e14.
PMID:
35649411
; PMCID:
PMC9271637
.
Citations:
1
Translation:
Animals
Cells
Simmons DP
, Nguyen HN, Gomez-Rivas E,
Jeong Y
,
Jonsson AH
,
Chen AF
,
Lange JK
,
Dyer GS
,
Blazar P
,
Earp BE
,
Coblyn JS
,
Massarotti EM
,
Sparks JA
,
Todd DJ
,
Rao DA
,
Kim EY
,
Brenner MB
. SLAMF7 engagement superactivates macrophages in acute and chronic inflammation. Sci Immunol. 2022 02 11; 7(68):eabf2846.
PMID:
35148199
; PMCID:
PMC8991457
.
Citations:
1
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Wei K
, Nguyen HN,
Brenner MB
. Fibroblast pathology in inflammatory diseases. J Clin Invest. 2021 10 15; 131(20).
PMID:
34651581
; PMCID:
PMC8516469
.
Citations:
5
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Svensson MND, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody KM,
Slowikowski K
, Mizoguchi F, Humby F, Hands R, Santelli E, Sacchetti C, Wakabayashi K, Wu DJ, Barback C, Ai R, Wang W, Sims GP, Mydel P, Kasama T, Boyle DL, Galimi F, Vera D, Tremblay ML,
Raychaudhuri S
,
Brenner MB
, Firestein GS, Pitzalis C, Ekwall AH, Stanford SM, Bottini N. Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal. Sci Adv. 2020 06; 6(26):eaba4353.
PMID:
32637608
; PMCID:
PMC7319753
.
Citations:
8
Fields:
Sci
Science
Translation:
Animals
Cells
LaMarche NM, Kane H, Kohlgruber AC, Dong H,
Lynch L
,
Brenner MB
. Distinct iNKT Cell Populations Use IFN? or ER Stress-Induced IL-10 to Control Adipose Tissue Homeostasis. Cell Metab. 2020 08 04; 32(2):243-258.e6.
PMID:
32516575
.
Citations:
18
Fields:
Cel
Cell Biology
Met
Metabolism
Translation:
Animals
Cells
Kim EY
, Ner-Gaon H, Varon J, Cullen AM, Guo J, Choi J, Barragan-Bradford D, Higuera A, Pinilla-Vera M, Short SA, Arciniegas-Rubio A,
Tamura T
,
Leaf DE
,
Baron RM
, Shay T,
Brenner MB
. Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-? in NK cells. J Clin Invest. 2020 06 01; 130(6):3238-3252.
PMID:
32154791
; PMCID:
PMC7260006
.
Citations:
12
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Wei K
,
Korsunsky I
, Marshall JL, Gao A,
Watts GFM
, Major T, Croft AP, Watts J,
Blazar PE
,
Lange JK
,
Thornhill TS
, Filer A, Raza K, Donlin LT, Siebel CW, Buckley CD,