Harvard Catalyst Profiles

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Norma Preckel Gerard, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI121386 (GERARD, NORMA P) Dec 1, 2015 - Nov 30, 2020
    Targeting Innate Immunity in Staphylococcal Infection
    Role: Principal Investigator
  2. P50HL067669 (KOUREMBANAS, STELLA) Sep 30, 2001 - Jul 31, 2007
    Injury, inflammation &repair: effect on developing lung
    Role: Co-Principal Investigator
  3. P01HL067669 (KOUREMBANAS, STELLA) Sep 30, 2001 - Jul 31, 2006
    Injury, inflammation &repair: effect on developing lung
    Role: Co-Principal Investigator
  4. R01HL041587 (GERARD, NORMA P) Dec 1, 1988 - Apr 30, 2006
    Role: Principal Investigator
  5. K04HL001777 (GERARD, NORMA P) Sep 1, 1985 - Aug 31, 1990
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zsengellér ZK, Gerard NP. The oxidation state of cysteine thiols on the ectodomain of TLR2 and TLR4 influences intracellular signaling. Immunobiology. 2020 03; 225(2):151895. PMID: 31843260.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  2. Cardet JC, Jiang X, Lu Q, Gerard N, McIntire K, Boushey HA, Castro M, Chinchilli VM, Codispoti CD, Dyer AM, Holguin F, Kraft M, Lazarus S, Lemanske RF, Lugogo N, Mauger D, Moore WC, Moy J, Ortega VE, Peters SP, Smith LJ, Solway J, Sorkness CA, Sumino K, Wechsler ME, Wenzel S, Israel E. Reply. J Allergy Clin Immunol. 2019 09; 144(3):873-874. PMID: 31300279.
    Citations:    Fields:    
  3. Polverino F, Lu B, Quintero JR, Vargas SO, Patel AS, Owen CA, Gerard NP, Gerard C, Cernadas M. CFTR regulates B cell activation and lymphoid follicle development. Respir Res. 2019 Jul 01; 20(1):133. PMID: 31262295; PMCID: PMC6604167.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  4. Wang W, Shen M, Fischer C, Basu R, Hazra S, Couvineau P, Paul M, Wang F, Toth S, Mix DS, Poglitsch M, Gerard NP, Bouvier M, Vederas JC, Penninger JM, Kassiri Z, Oudit GY. Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs. Proc Natl Acad Sci U S A. 2019 06 25; 116(26):13006-13015. PMID: 31189595; PMCID: PMC6600956.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  5. Cardet JC, Jiang X, Lu Q, Gerard N, McIntire K, Boushey HA, Castro M, Chinchilli VM, Codispoti CD, Dyer AM, Holguin F, Kraft M, Lazarus S, Lemanske RF, Lugogo N, Mauger D, Moore WC, Moy J, Ortega VE, Peters SP, Smith LJ, Solway J, Sorkness CA, Sumino K, Wechsler ME, Wenzel S, Israel E. Loss of bronchoprotection with ICS plus LABA treatment, ß-receptor dynamics, and the effect of alendronate. J Allergy Clin Immunol. 2019 08; 144(2):416-425.e7. PMID: 30872116; PMCID: PMC6950766.
    Citations: 1     Fields:    Translation:Humans
  6. Natarajan N, Abbas Y, Bryant DM, Gonzalez-Rosa JM, Sharpe M, Uygur A, Cocco-Delgado LH, Ho NN, Gerard NP, Gerard CJ, MacRae CA, Burns CE, Burns CG, Whited JL, Lee RT. Complement Receptor C5aR1 Plays an Evolutionarily Conserved Role in Successful Cardiac Regeneration. Circulation. 2018 05 15; 137(20):2152-2165. PMID: 29348261; PMCID: PMC5953786.
    Citations: 28     Fields:    Translation:AnimalsCells
  7. Agrawal PB, Wang R, Li HL, Schmitz-Abe K, Simone-Roach C, Chen J, Shi J, Louie T, Sheng S, Towne MC, Brainson CF, Matthay MA, Kim CF, Bamshad M, Emond MJ, Gerard NP, Kleyman TR, Gerard C. The Epithelial Sodium Channel Is a Modifier of the Long-Term Nonprogressive Phenotype Associated with F508del CFTR Mutations. Am J Respir Cell Mol Biol. 2017 12; 57(6):711-720. PMID: 28708422; PMCID: PMC5765421.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  8. Wang R, Lu B, Gerard C, Gerard NP. C5L2, the Second C5a Anaphylatoxin Receptor, Suppresses LPS-Induced Acute Lung Injury. Am J Respir Cell Mol Biol. 2016 11; 55(5):657-666. PMID: 27285858; PMCID: PMC5105183.
    Citations: 8     Fields:    Translation:AnimalsCells
  9. Gaddipati S, Rao P, Jerome AD, Burugula BB, Gerard NP, Suvas S. Loss of Neurokinin-1 Receptor Alters Ocular Surface Homeostasis and Promotes an Early Development of Herpes Stromal Keratitis. J Immunol. 2016 11 15; 197(10):4021-4033. PMID: 27798158; PMCID: PMC5113833.
    Citations: 15     Fields:    Translation:AnimalsCells
  10. Gerard NP, Gerard C. Cloning of the Human C5a Anaphylatoxin Receptor, and More. Front Immunol. 2015; 6:445. PMID: 26388870.
    Citations: 1     Fields:    
  11. Spaan AN, Schiepers A, de Haas CJ, van Hooijdonk DD, Badiou C, Contamin H, Vandenesch F, Lina G, Gerard NP, Gerard C, van Kessel KP, Henry T, van Strijp JA. Differential Interaction of the Staphylococcal Toxins Panton-Valentine Leukocidin and ?-Hemolysin CB with Human C5a Receptors. J Immunol. 2015 Aug 01; 195(3):1034-43. PMID: 26091719; PMCID: PMC4506853.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  12. Xiao H, Dairaghi DJ, Powers JP, Ertl LS, Baumgart T, Wang Y, Seitz LC, Penfold ME, Gan L, Hu P, Lu B, Gerard NP, Gerard C, Schall TJ, Jaen JC, Falk RJ, Jennette JC. C5a receptor (CD88) blockade protects against MPO-ANCA GN. J Am Soc Nephrol. 2014 Feb; 25(2):225-31. PMID: 24179165.
    Citations: 111     Fields:    Translation:HumansAnimalsCells
  13. Rajagopal S, Bassoni DL, Campbell JJ, Gerard NP, Gerard C, Wehrman TS. Biased agonism as a mechanism for differential signaling by chemokine receptors. J Biol Chem. 2013 Dec 06; 288(49):35039-48. PMID: 24145037.
    Citations: 53     Fields:    Translation:HumansCells
  14. Wang R, Lu B, Gerard C, Gerard NP. Disruption of the complement anaphylatoxin receptor C5L2 exacerbates inflammation in allergic contact dermatitis. J Immunol. 2013 Oct 15; 191(8):4001-9. PMID: 24043888; PMCID: PMC4551435.
    Citations: 17     Fields:    Translation:AnimalsCells
  15. Roy C, Gupta A, Fisette A, Lapointe M, Poursharifi P, Richard D, Lu H, Lu B, Gerard N, Gerard C, Cianflone K. C5a receptor deficiency alters energy utilization and fat storage. PLoS One. 2013; 8(5):e62531. PMID: 23667486.
    Citations: 9     Fields:    Translation:Animals
  16. Agnello D, Denimal D, Lavaux A, Blondeau-Germe L, Lu B, Gerard NP, Gerard C, Pothier P. Intrarectal immunization and IgA antibody-secreting cell homing to the small intestine. J Immunol. 2013 May 01; 190(9):4836-47. PMID: 23547118.
    Citations: 10     Fields:    Translation:AnimalsCellsPHPublic Health
  17. Berger A, Frelin C, Shah DK, Benveniste P, Herrington R, Gerard NP, Zúñiga-Pflücker JC, Iscove NN, Paige CJ. Neurokinin-1 receptor signalling impacts bone marrow repopulation efficiency. PLoS One. 2013; 8(3):e58787. PMID: 23516556.
    Citations: 2     Fields:    Translation:AnimalsCells
  18. Schäfer B, Piliponsky AM, Oka T, Song CH, Gerard NP, Gerard C, Tsai M, Kalesnikoff J, Galli SJ. Mast cell anaphylatoxin receptor expression can enhance IgE-dependent skin inflammation in mice. J Allergy Clin Immunol. 2013 Feb; 131(2):541-8.e1-9. PMID: 22728083; PMCID: PMC3597773.
    Citations: 46     Fields:    Translation:AnimalsCells
  19. Berger A, Tran AH, Dida J, Minkin S, Gerard NP, Yeomans J, Paige CJ. Diminished pheromone-induced sexual behavior in neurokinin-1 receptor deficient (TACR1(-/-)) mice. Genes Brain Behav. 2012 Jul; 11(5):568-76. PMID: 22471406.
    Citations: 7     Fields:    Translation:Animals
  20. Kan L, Lounev VY, Pignolo RJ, Duan L, Liu Y, Stock SR, McGuire TL, Lu B, Gerard NP, Shore EM, Kaplan FS, Kessler JA. Substance P signaling mediates BMP-dependent heterotopic ossification. J Cell Biochem. 2011 Oct; 112(10):2759-72. PMID: 21748788.
    Citations: 57     Fields:    Translation:HumansAnimalsCells
  21. Bera MM, Lu B, Martin TR, Cui S, Rhein LM, Gerard C, Gerard NP. Th17 cytokines are critical for respiratory syncytial virus-associated airway hyperreponsiveness through regulation by complement C3a and tachykinins. J Immunol. 2011 Oct 15; 187(8):4245-55. PMID: 21918196; PMCID: PMC3186836.
    Citations: 32     Fields:    Translation:AnimalsCells
  22. Karagiannides I, Stavrakis D, Bakirtzi K, Kokkotou E, Pirtskhalava T, Nayeb-Hashemi H, Bowe C, Bugni JM, Nuño M, Lu B, Gerard NP, Leeman SE, Kirkland JL, Pothoulakis C. Substance P (SP)-neurokinin-1 receptor (NK-1R) alters adipose tissue responses to high-fat diet and insulin action. Endocrinology. 2011 Jun; 152(6):2197-205. PMID: 21467195; PMCID: PMC3100617.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  23. Nigrovic PA, Malbec O, Lu B, Markiewski MM, Kepley C, Gerard N, Gerard C, Daëron M, Lee DM. C5a receptor enables participation of mast cells in immune complex arthritis independently of Fc? receptor modulation. Arthritis Rheum. 2010 Nov; 62(11):3322-33. PMID: 20662064; PMCID: PMC2970731.
    Citations: 17     Fields:    Translation:AnimalsCells
  24. Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, König P, Gerard NP, Gerard C, Wills-Karp M, Köhl J. A critical role for C5L2 in the pathogenesis of experimental allergic asthma. J Immunol. 2010 Dec 01; 185(11):6741-52. PMID: 20974988.
    Citations: 39     Fields:    Translation:AnimalsCells
  25. Koon HW, Shih D, Karagiannides I, Zhao D, Fazelbhoy Z, Hing T, Xu H, Lu B, Gerard N, Pothoulakis C. Substance P modulates colitis-associated fibrosis. Am J Pathol. 2010 Nov; 177(5):2300-9. PMID: 20889569; PMCID: PMC2966789.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  26. Bamberg CE, Mackay CR, Lee H, Zahra D, Jackson J, Lim YS, Whitfeld PL, Craig S, Corsini E, Lu B, Gerard C, Gerard NP. The C5a receptor (C5aR) C5L2 is a modulator of C5aR-mediated signal transduction. J Biol Chem. 2010 Mar 05; 285(10):7633-44. PMID: 20044484.
    Citations: 99     Fields:    Translation:HumansAnimalsCells
  27. Rajagopal S, Kim J, Ahn S, Craig S, Lam CM, Gerard NP, Gerard C, Lefkowitz RJ. Beta-arrestin- but not G protein-mediated signaling by the "decoy" receptor CXCR7. Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2):628-32. PMID: 20018651.
    Citations: 247     Fields:    Translation:HumansAnimalsCells
  28. Dib M, Zsengeller Z, Mitsialis A, Lu B, Craig S, Gerard C, Gerard NP. A paradoxical protective role for the proinflammatory peptide substance P receptor (NK1R) in acute hyperoxic lung injury. Am J Physiol Lung Cell Mol Physiol. 2009 Oct; 297(4):L687-97. PMID: 19633070.
    Citations: 8     Fields:    Translation:AnimalsCells
  29. Markiewski MM, DeAngelis RA, Strey CW, Foukas PG, Gerard C, Gerard N, Wetsel RA, Lambris JD. The regulation of liver cell survival by complement. J Immunol. 2009 May 01; 182(9):5412-8. PMID: 19380788; PMCID: PMC2732128.
    Citations: 46     Fields:    Translation:Animals
  30. Dempsey EC, Wick MJ, Karoor V, Barr EJ, Tallman DW, Wehling CA, Walchak SJ, Laudi S, Le M, Oka M, Majka S, Cool CD, Fagan KA, Klemm DJ, Hersh LB, Gerard NP, Gerard C, Miller YE. Neprilysin null mice develop exaggerated pulmonary vascular remodeling in response to chronic hypoxia. Am J Pathol. 2009 Mar; 174(3):782-96. PMID: 19234135; PMCID: PMC2665740.
    Citations: 31     Fields:    Translation:Animals
  31. Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Köhl J, Gerard C, Sarma JV, Ward PA. Functional roles for C5a receptors in sepsis. Nat Med. 2008 May; 14(5):551-7. PMID: 18454156.
    Citations: 186     Fields:    Translation:Animals
  32. Rhein LM, Perkins M, Gerard NP, Gerard C. FcgammaRIII is protective against Pseudomonas aeruginosa pneumonia. Am J Respir Cell Mol Biol. 2008 Apr; 38(4):401-6. PMID: 17975174.
    Citations: 10     Fields:    Translation:AnimalsCells
  33. Grasemann H, Gerard NP, De Sanctis GT. Ventilatory responses to acute hypoxia in neurokinin-1 receptor deficient mice. Respir Physiol Neurobiol. 2007 Nov 15; 159(2):227-31. PMID: 17869190.
    Citations:    Fields:    Translation:Animals
  34. Mukhopadhyay P, Bátkai S, Rajesh M, Czifra N, Harvey-White J, Haskó G, Zsengeller Z, Gerard NP, Liaudet L, Kunos G, Pacher P. Pharmacological inhibition of CB1 cannabinoid receptor protects against doxorubicin-induced cardiotoxicity. J Am Coll Cardiol. 2007 Aug 07; 50(6):528-36. PMID: 17678736; PMCID: PMC2239316.
    Citations: 101     Fields:    Translation:AnimalsCells
  35. Gazzieri D, Trevisani M, Springer J, Harrison S, Cottrell GS, Andre E, Nicoletti P, Massi D, Zecchi S, Nosi D, Santucci M, Gerard NP, Lucattelli M, Lungarella G, Fischer A, Grady EF, Bunnett NW, Geppetti P. Substance P released by TRPV1-expressing neurons produces reactive oxygen species that mediate ethanol-induced gastric injury. Free Radic Biol Med. 2007 Aug 15; 43(4):581-9. PMID: 17640568.
    Citations: 24     Fields:    Translation:AnimalsCells
  36. Makhortova NR, Askovich P, Patterson CE, Gechman LA, Gerard NP, Rall GF. Neurokinin-1 enables measles virus trans-synaptic spread in neurons. Virology. 2007 May 25; 362(1):235-44. PMID: 17434199.
    Citations: 47     Fields:    Translation:AnimalsCells
  37. Melendi GA, Hoffman SJ, Karron RA, Irusta PM, Laham FR, Humbles A, Schofield B, Pan CH, Rabold R, Thumar B, Thumar A, Gerard NP, Mitzner W, Barnum SR, Gerard C, Kleeberger SR, Polack FP. C5 modulates airway hyperreactivity and pulmonary eosinophilia during enhanced respiratory syncytial virus disease by decreasing C3a receptor expression. J Virol. 2007 Jan; 81(2):991-9. PMID: 17079327; PMCID: PMC1797434.
    Citations: 14     Fields:    Translation:AnimalsCells
  38. Lucattelli M, Fineschi S, Geppetti P, Gerard NP, Lungarella G. Neurokinin-1 receptor blockade and murine lung tumorigenesis. Am J Respir Crit Care Med. 2006 Sep 15; 174(6):674-83. PMID: 16799078.
    Citations: 6     Fields:    Translation:Animals
  39. Gerard NP, Lu B, Liu P, Craig S, Fujiwara Y, Okinaga S, Gerard C. An anti-inflammatory function for the complement anaphylatoxin C5a-binding protein, C5L2. J Biol Chem. 2005 Dec 02; 280(48):39677-80. PMID: 16204243.
    Citations: 86     Fields:    Translation:AnimalsCells
  40. Honczarenko M, Lu B, Nicholson-Weller A, Gerard NP, Silberstein LE, Gerard C. C5L2 receptor is not involved in C3a / C3a-desArg-mediated enhancement of bone marrow hematopoietic cell migration to CXCL12. Leukemia. 2005 Sep; 19(9):1682-3; author reply 1684-5. PMID: 15990859.
    Citations: 8     Fields:    Translation:AnimalsCells
  41. D'Andrea MR, Saban MR, Gerard NP, Wershil BK, Saban R. Lack of neurokinin-1 receptor expression affects tissue mast cell numbers but not their spatial relationship with nerves. Am J Physiol Regul Integr Comp Physiol. 2005 Feb; 288(2):R491-500. PMID: 15458971.
    Citations: 9     Fields:    Translation:AnimalsCells
  42. Humbles AA, Lloyd CM, McMillan SJ, Friend DS, Xanthou G, McKenna EE, Ghiran S, Gerard NP, Yu C, Orkin SH, Gerard C. A critical role for eosinophils in allergic airways remodeling. Science. 2004 Sep 17; 305(5691):1776-9. PMID: 15375268.
    Citations: 307     Fields:    Translation:AnimalsCells
  43. Iwata N, Mizukami H, Shirotani K, Takaki Y, Muramatsu S, Lu B, Gerard NP, Gerard C, Ozawa K, Saido TC. Presynaptic localization of neprilysin contributes to efficient clearance of amyloid-beta peptide in mouse brain. J Neurosci. 2004 Jan 28; 24(4):991-8. PMID: 14749444; PMCID: PMC6729819.
    Citations: 86     Fields:    Translation:HumansAnimalsCells
  44. Lever IJ, Grant AD, Pezet S, Gerard NP, Brain SD, Malcangio M. Basal and activity-induced release of substance P from primary afferent fibres in NK1 receptor knockout mice: evidence for negative feedback. Neuropharmacology. 2003 Dec; 45(8):1101-10. PMID: 14614953.
    Citations: 9     Fields:    Translation:Animals
  45. Barbara G, De Giorgio R, Stanghellini V, Corinaldesi R, Cremon C, Gerard N, Gerard C, Grady EF, Bunnett NW, Blennerhassett PA, Collins SM. Neutral endopeptidase (EC downregulates the onset of intestinal inflammation in the nematode infected mouse. Gut. 2003 Oct; 52(10):1457-64. PMID: 12970139; PMCID: PMC1773836.
    Citations: 13     Fields:    Translation:Animals
  46. Seiler P, Aichele P, Bandermann S, Hauser AE, Lu B, Gerard NP, Gerard C, Ehlers S, Mollenkopf HJ, Kaufmann SH. Early granuloma formation after aerosol Mycobacterium tuberculosis infection is regulated by neutrophils via CXCR3-signaling chemokines. Eur J Immunol. 2003 Oct; 33(10):2676-86. PMID: 14515251.
    Citations: 82     Fields:    Translation:AnimalsCells
  47. van der Kleij HP, Kraneveld AD, Redegeld FA, Gerard NP, Morteau O, Nijkamp FP. The tachykinin NK1 receptor is crucial for the development of non-atopic airway inflammation and hyperresponsiveness. Eur J Pharmacol. 2003 Aug 29; 476(3):249-55. PMID: 12969772.
    Citations: 4     Fields:    Translation:AnimalsCells
  48. Okinaga S, Slattery D, Humbles A, Zsengeller Z, Morteau O, Kinrade MB, Brodbeck RM, Krause JE, Choe HR, Gerard NP, Gerard C. C5L2, a nonsignaling C5A binding protein. Biochemistry. 2003 Aug 12; 42(31):9406-15. PMID: 12899627.
    Citations: 92     Fields:    Translation:HumansAnimalsCells
  49. Kandere-Grzybowska K, Gheorghe D, Priller J, Esposito P, Huang M, Gerard N, Theoharides TC. Stress-induced dura vascular permeability does not develop in mast cell-deficient and neurokinin-1 receptor knockout mice. Brain Res. 2003 Aug 08; 980(2):213-20. PMID: 12867261.
    Citations: 16     Fields:    Translation:AnimalsCells
  50. Gao J, Choe H, Bota D, Wright PL, Gerard C, Gerard NP. Sulfation of tyrosine 174 in the human C3a receptor is essential for binding of C3a anaphylatoxin. J Biol Chem. 2003 Sep 26; 278(39):37902-8. PMID: 12871936.
    Citations: 17     Fields:    Translation:HumansCells
  51. Dozmorov I, Saban MR, Gerard NP, Lu B, Nguyen NB, Centola M, Saban R. Neurokinin 1 receptors and neprilysin modulation of mouse bladder gene regulation. Physiol Genomics. 2003 Feb 06; 12(3):239-50. PMID: 12499446.
    Citations: 12     Fields:    Translation:Animals
  52. Gerard NP, Gerard C. Complement in allergy and asthma. Curr Opin Immunol. 2002 Dec; 14(6):705-8. PMID: 12413519.
    Citations: 21     Fields:    Translation:Animals
  53. Saban R, Gerard NP, Saban MR, Nguyen NB, DeBoer DJ, Wershil BK. Mast cells mediate substance P-induced bladder inflammation through an NK(1) receptor-independent mechanism. Am J Physiol Renal Physiol. 2002 Oct; 283(4):F616-29. PMID: 12217852.
    Citations: 26     Fields:    Translation:AnimalsCells
  54. Grant AD, Akhtar R, Gerard NP, Brain SD. Neurokinin B induces oedema formation in mouse lung via tachykinin receptor-independent mechanisms. J Physiol. 2002 Sep 15; 543(Pt 3):1007-14. PMID: 12231654; PMCID: PMC2290535.
    Citations: 7     Fields:    Translation:Animals
  55. Farzan M, Chung S, Li W, Vasilieva N, Wright PL, Schnitzler CE, Marchione RJ, Gerard C, Gerard NP, Sodroski J, Choe H. Tyrosine-sulfated peptides functionally reconstitute a CCR5 variant lacking a critical amino-terminal region. J Biol Chem. 2002 Oct 25; 277(43):40397-402. PMID: 12183462.
    Citations: 31     Fields:    Translation:Cells
  56. Fukami S, Watanabe K, Iwata N, Haraoka J, Lu B, Gerard NP, Gerard C, Fraser P, Westaway D, St George-Hyslop P, Saido TC. Abeta-degrading endopeptidase, neprilysin, in mouse brain: synaptic and axonal localization inversely correlating with Abeta pathology. Neurosci Res. 2002 May; 43(1):39-56. PMID: 12074840.
    Citations: 52     Fields:    Translation:AnimalsCells
  57. Castagliuolo I, Morteau O, Keates AC, Valenick L, Wang CC, Zacks J, Lu B, Gerard NP, Pothoulakis C. Protective effects of neurokinin-1 receptor during colitis in mice: role of the epidermal growth factor receptor. Br J Pharmacol. 2002 May; 136(2):271-9. PMID: 12010776; PMCID: PMC1573337.
    Citations: 30     Fields:    Translation:Animals
  58. Rappert A, Biber K, Nolte C, Lipp M, Schubel A, Lu B, Gerard NP, Gerard C, Boddeke HW, Kettenmann H. Secondary lymphoid tissue chemokine (CCL21) activates CXCR3 to trigger a Cl- current and chemotaxis in murine microglia. J Immunol. 2002 Apr 01; 168(7):3221-6. PMID: 11907075.
    Citations: 47     Fields:    Translation:AnimalsCells
  59. Morteau O, Castagliuolo I, Mykoniatis A, Zacks J, Wlk M, Lu B, Pothoulakis C, Gerard NP, Gerard C. Genetic deficiency in the chemokine receptor CCR1 protects against acute Clostridium difficile toxin A enteritis in mice. Gastroenterology. 2002 Mar; 122(3):725-33. PMID: 11875005.
    Citations: 13     Fields:    Translation:Animals
  60. Humbles AA, Lu B, Friend DS, Okinaga S, Lora J, Al-Garawi A, Martin TR, Gerard NP, Gerard C. The murine CCR3 receptor regulates both the role of eosinophils and mast cells in allergen-induced airway inflammation and hyperresponsiveness. Proc Natl Acad Sci U S A. 2002 Feb 05; 99(3):1479-84. PMID: 11830666; PMCID: PMC122216.
    Citations: 112     Fields:    Translation:AnimalsCells
  61. Grant AD, Gerard NP, Brain SD. Evidence of a role for NK1 and CGRP receptors in mediating neurogenic vasodilatation in the mouse ear. Br J Pharmacol. 2002 Jan; 135(2):356-62. PMID: 11815370; PMCID: PMC1573148.
    Citations: 19     Fields:    Translation:Animals
  62. Rawlingson A, Gerard NP, Brain SD. Interactive contribution of NK(1) and kinin receptors to the acute inflammatory oedema observed in response to noxious heat stimulation: studies in NK(1) receptor knockout mice. Br J Pharmacol. 2001 Dec; 134(8):1805-13. PMID: 11739258; PMCID: PMC1572912.
    Citations: 4     Fields:    Translation:AnimalsCells
  63. Morteau O, Lu B, Gerard C, Gerard NP. Hemokinin 1 is a full agonist at the substance P receptor. Nat Immunol. 2001 Dec; 2(12):1088. PMID: 11725292.
    Citations: 20     Fields:    Translation:AnimalsCells
  64. Kirkwood KS, Bunnett NW, Maa J, Castagliolo I, Liu B, Gerard N, Zacks J, Pothoulakis C, Grady EF. Deletion of neutral endopeptidase exacerbates intestinal inflammation induced by Clostridium difficile toxin A. Am J Physiol Gastrointest Liver Physiol. 2001 Aug; 281(2):G544-51. PMID: 11447035.
    Citations: 15     Fields:    Translation:AnimalsCells
  65. Vergnolle N, Bunnett NW, Sharkey KA, Brussee V, Compton SJ, Grady EF, Cirino G, Gerard N, Basbaum AI, Andrade-Gordon P, Hollenberg MD, Wallace JL. Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway. Nat Med. 2001 Jul; 7(7):821-6. PMID: 11433347.
    Citations: 152     Fields:    Translation:Animals
  66. Iwata N, Tsubuki S, Takaki Y, Shirotani K, Lu B, Gerard NP, Gerard C, Hama E, Lee HJ, Saido TC. Metabolic regulation of brain Abeta by neprilysin. Science. 2001 May 25; 292(5521):1550-2. PMID: 11375493.
    Citations: 325     Fields:    Translation:HumansAnimalsCells
  67. Farzan M, Schnitzler CE, Vasilieva N, Leung D, Kuhn J, Gerard C, Gerard NP, Choe H. Sulfated tyrosines contribute to the formation of the C5a docking site of the human C5a anaphylatoxin receptor. J Exp Med. 2001 May 07; 193(9):1059-66. PMID: 11342590; PMCID: PMC2193433.
    Citations: 26     Fields:    Translation:HumansCells
  68. Gerard C, Gerard NP. Chemokines: back to the future? Nat Cell Biol. 2001 Feb; 3(2):E53-4. PMID: 11175764.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  69. Scholzen TE, Steinhoff M, Bonaccorsi P, Klein R, Amadesi S, Geppetti P, Lu B, Gerard NP, Olerud JE, Luger TA, Bunnett NW, Grady EF, Armstrong CA, Ansel JC. Neutral endopeptidase terminates substance P-induced inflammation in allergic contact dermatitis. J Immunol. 2001 Jan 15; 166(2):1285-91. PMID: 11145711.
    Citations: 23     Fields:    Translation:Animals
  70. Cao T, Grant AD, Gerard NP, Brain SD. Lack of a significant effect of deletion of the tachykinin neurokinin-1 receptor on wound healing in mouse skin. Neuroscience. 2001; 108(4):695-700. PMID: 11738504.
    Citations: 4     Fields:    Translation:Animals
  71. Takaki Y, Iwata N, Tsubuki S, Taniguchi S, Toyoshima S, Lu B, Gerard NP, Gerard C, Lee HJ, Shirotani K, Saido TC. Biochemical identification of the neutral endopeptidase family member responsible for the catabolism of amyloid beta peptide in the brain. J Biochem. 2000 Dec; 128(6):897-902. PMID: 11098130.
    Citations: 26     Fields:    Translation:AnimalsCells
  72. Hancock WW, Lu B, Gao W, Csizmadia V, Faia K, King JA, Smiley ST, Ling M, Gerard NP, Gerard C. Requirement of the chemokine receptor CXCR3 for acute allograft rejection. J Exp Med. 2000 Nov 20; 192(10):1515-20. PMID: 11085753; PMCID: PMC2193193.
    Citations: 176     Fields:    Translation:AnimalsCells
  73. Farzan M, Vasilieva N, Schnitzler CE, Chung S, Robinson J, Gerard NP, Gerard C, Choe H, Sodroski J. A tyrosine-sulfated peptide based on the N terminus of CCR5 interacts with a CD4-enhanced epitope of the HIV-1 gp120 envelope glycoprotein and inhibits HIV-1 entry. J Biol Chem. 2000 Oct 27; 275(43):33516-21. PMID: 10938094.
    Citations: 66     Fields:    Translation:HumansAnimalsCells
  74. Humbles AA, Lu B, Nilsson CA, Lilly C, Israel E, Fujiwara Y, Gerard NP, Gerard C. A role for the C3a anaphylatoxin receptor in the effector phase of asthma. Nature. 2000 Aug 31; 406(6799):998-1001. PMID: 10984054.
    Citations: 112     Fields:    Translation:HumansAnimalsCTClinical Trials
  75. Grady EF, Yoshimi SK, Maa J, Valeroso D, Vartanian RK, Rahim S, Kim EH, Gerard C, Gerard N, Bunnett NW, Kirkwood KS. Substance P mediates inflammatory oedema in acute pancreatitis via activation of the neurokinin-1 receptor in rats and mice. Br J Pharmacol. 2000 Jun; 130(3):505-12. PMID: 10821777; PMCID: PMC1572103.
    Citations: 24     Fields:    Translation:Animals
  76. Cao T, Pintér E, Al-Rashed S, Gerard N, Hoult JR, Brain SD. Neurokinin-1 receptor agonists are involved in mediating neutrophil accumulation in the inflamed, but not normal, cutaneous microvasculature: an in vivo study using neurokinin-1 receptor knockout mice. J Immunol. 2000 May 15; 164(10):5424-9. PMID: 10799908.
    Citations: 25     Fields:    Translation:AnimalsCells
  77. Jarmin DI, Rits M, Bota D, Gerard NP, Graham GJ, Clark-Lewis I, Gerard C. Cutting edge: identification of the orphan receptor G-protein-coupled receptor 2 as CCR10, a specific receptor for the chemokine ESkine. J Immunol. 2000 Apr 01; 164(7):3460-4. PMID: 10725696.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  78. Saban R, Saban MR, Nguyen NB, Lu B, Gerard C, Gerard NP, Hammond TG. Neurokinin-1 (NK-1) receptor is required in antigen-induced cystitis. Am J Pathol. 2000 Mar; 156(3):775-80. PMID: 10702392; PMCID: PMC1876835.
    Citations: 21     Fields:    Translation:AnimalsCellsPHPublic Health
  79. Slattery DM, Gerard N, Gerard C. Gene targeting of chemokines and their receptors. Springer Semin Immunopathol. 2000; 22(4):417-32. PMID: 11155444.
    Citations: 1     Fields:    Translation:HumansAnimals
  80. Saban R, Nguyen N, Saban MR, Gerard NP, Pasricha PJ. Nerve-mediated motility of ileal segments isolated from NK(1) receptor knockout mice. Am J Physiol. 1999 12; 277(6):G1173-9. PMID: 10600814.
    Citations: 6     Fields:    Translation:AnimalsCells
  81. Lu B, Humbles A, Bota D, Gerard C, Moser B, Soler D, Luster AD, Gerard NP. Structure and function of the murine chemokine receptor CXCR3. Eur J Immunol. 1999 11; 29(11):3804-12. PMID: 10556837.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  82. Grasemann H, Lu B, Jiao A, Boudreau J, Gerard NP, De Sanctis GT. Targeted deletion of the neutral endopeptidase gene alters ventilatory responses to acute hypoxia in mice. J Appl Physiol (1985). 1999 Oct; 87(4):1266-71. PMID: 10517751.
    Citations: 1     Fields:    Translation:Animals
  83. Sturiale S, Barbara G, Qiu B, Figini M, Geppetti P, Gerard N, Gerard C, Grady EF, Bunnett NW, Collins SM. Neutral endopeptidase (EC terminates colitis by degrading substance P. Proc Natl Acad Sci U S A. 1999 Sep 28; 96(20):11653-8. PMID: 10500232; PMCID: PMC18089.
    Citations: 49     Fields:    Translation:HumansAnimals
  84. Cao T, Gerard NP, Brain SD. Use of NK(1) knockout mice to analyze substance P-induced edema formation. Am J Physiol. 1999 08; 277(2):R476-81. PMID: 10444554.
    Citations: 16     Fields:    Translation:Animals
  85. Jassim N, Al-Arrayed S, Gerard N, Al-Mukharraq H, Al-Ajami A, Ramasawmy R, Krishnamoorthy R. A mismatched-primer polymerase chain reaction-restriction fragment length polymorphism strategy for rapid screening of the polyadenylation signal mutation alpha(T-Saudi) (AATAAA-->AATAAG) in the alpha2-globin gene. Hemoglobin. 1999 Aug; 23(3):213-20. PMID: 10490133.
    Citations: 4     Fields:    Translation:Humans
  86. Schenten D, Marcon L, Karlsson GB, Parolin C, Kodama T, Gerard N, Sodroski J. Effects of soluble CD4 on simian immunodeficiency virus infection of CD4-positive and CD4-negative cells. J Virol. 1999 Jul; 73(7):5373-80. PMID: 10364284; PMCID: PMC112593.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  87. Blum AM, Metwali A, Kim-Miller M, Li J, Qadir K, Elliott DE, Lu B, Fabry Z, Gerard N, Weinstock JV. The substance P receptor is necessary for a normal granulomatous response in murine schistosomiasis mansoni. J Immunol. 1999 May 15; 162(10):6080-5. PMID: 10229849.
    Citations: 17     Fields:    Translation:AnimalsCells
  88. Farzan M, Mirzabekov T, Kolchinsky P, Wyatt R, Cayabyab M, Gerard NP, Gerard C, Sodroski J, Choe H. Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry. Cell. 1999 Mar 05; 96(5):667-76. PMID: 10089882.
    Citations: 267     Fields:    Translation:HumansAnimalsCells
  89. Sabroe I, Conroy DM, Gerard NP, Li Y, Collins PD, Post TW, Jose PJ, Williams TJ, Gerard CJ, Ponath PD. Cloning and characterization of the guinea pig eosinophil eotaxin receptor, C-C chemokine receptor-3: blockade using a monoclonal antibody in vivo. J Immunol. 1998 Dec 01; 161(11):6139-47. PMID: 9834099.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  90. Karlsson GB, Halloran M, Schenten D, Lee J, Racz P, Tenner-Racz K, Manola J, Gelman R, Etemad-Moghadam B, Desjardins E, Wyatt R, Gerard NP, Marcon L, Margolin D, Fanton J, Axthelm MK, Letvin NL, Sodroski J. The envelope glycoprotein ectodomains determine the efficiency of CD4+ T lymphocyte depletion in simian-human immunodeficiency virus-infected macaques. J Exp Med. 1998 Sep 21; 188(6):1159-71. PMID: 9743534; PMCID: PMC2212530.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  91. Choe H, Farzan M, Konkel M, Martin K, Sun Y, Marcon L, Cayabyab M, Berman M, Dorf ME, Gerard N, Gerard C, Sodroski J. The orphan seven-transmembrane receptor apj supports the entry of primary T-cell-line-tropic and dualtropic human immunodeficiency virus type 1. J Virol. 1998 Jul; 72(7):6113-8. PMID: 9621075; PMCID: PMC110417.
    Citations: 57     Fields:    Translation:HumansAnimalsCells
  92. Choe H, Martin KA, Farzan M, Sodroski J, Gerard NP, Gerard C. Structural interactions between chemokine receptors, gp120 Env and CD4. Semin Immunol. 1998 Jun; 10(3):249-57. PMID: 9653051.
    Citations: 15     Fields:    Translation:HumansCells
  93. Castagliuolo I, Riegler M, Pasha A, Nikulasson S, Lu B, Gerard C, Gerard NP, Pothoulakis C. Neurokinin-1 (NK-1) receptor is required in Clostridium difficile- induced enteritis. J Clin Invest. 1998 Apr 15; 101(8):1547-50. PMID: 9541482; PMCID: PMC508733.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  94. Bhatia M, Saluja AK, Hofbauer B, Frossard JL, Lee HS, Castagliuolo I, Wang CC, Gerard N, Pothoulakis C, Steer ML. Role of substance P and the neurokinin 1 receptor in acute pancreatitis and pancreatitis-associated lung injury. Proc Natl Acad Sci U S A. 1998 Apr 14; 95(8):4760-5. PMID: 9539812; PMCID: PMC22564.
    Citations: 82     Fields:    Translation:Animals
  95. Farzan M, Choe H, Vaca L, Martin K, Sun Y, Desjardins E, Ruffing N, Wu L, Wyatt R, Gerard N, Gerard C, Sodroski J. A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5. J Virol. 1998 Feb; 72(2):1160-4. PMID: 9445013; PMCID: PMC124591.
    Citations: 90     Fields:    Translation:HumansAnimalsCells
  96. Martin KA, Wyatt R, Farzan M, Choe H, Marcon L, Desjardins E, Robinson J, Sodroski J, Gerard C, Gerard NP. CD4-independent binding of SIV gp120 to rhesus CCR5. Science. 1997 Nov 21; 278(5342):1470-3. PMID: 9367961.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  97. Gerard C, Frossard JL, Bhatia M, Saluja A, Gerard NP, Lu B, Steer M. Targeted disruption of the beta-chemokine receptor CCR1 protects against pancreatitis-associated lung injury. J Clin Invest. 1997 Oct 15; 100(8):2022-7. PMID: 9329966; PMCID: PMC508392.
    Citations: 48     Fields:    Translation:Animals
  98. Höpken UE, Lu B, Gerard NP, Gerard C. Impaired inflammatory responses in the reverse arthus reaction through genetic deletion of the C5a receptor. J Exp Med. 1997 Aug 29; 186(5):749-56. PMID: 9271590; PMCID: PMC2199021.
    Citations: 49     Fields:    Translation:AnimalsCells
  99. Farzan M, Choe H, Martin K, Marcon L, Hofmann W, Karlsson G, Sun Y, Barrett P, Marchand N, Sullivan N, Gerard N, Gerard C, Sodroski J. Two orphan seven-transmembrane segment receptors which are expressed in CD4-positive cells support simian immunodeficiency virus infection. J Exp Med. 1997 Aug 04; 186(3):405-11. PMID: 9236192; PMCID: PMC2198994.
    Citations: 109     Fields:    Translation:HumansAnimalsCells
  100. Lu B, Figini M, Emanueli C, Geppetti P, Grady EF, Gerard NP, Ansell J, Payan DG, Gerard C, Bunnett N. The control of microvascular permeability and blood pressure by neutral endopeptidase. Nat Med. 1997 Aug; 3(8):904-7. PMID: 9256283.
    Citations: 48     Fields:    Translation:Animals
  101. Tanabe S, Heesen M, Yoshizawa I, Berman MA, Luo Y, Bleul CC, Springer TA, Okuda K, Gerard N, Dorf ME. Functional expression of the CXC-chemokine receptor-4/fusin on mouse microglial cells and astrocytes. J Immunol. 1997 Jul 15; 159(2):905-11. PMID: 9218610.
    Citations: 42     Fields:    Translation:AnimalsCells
  102. Heesen M, Berman MA, Höpken UE, Gerard NP, Dorf ME. Alternate splicing of mouse fusin/CXC chemokine receptor-4: stromal cell-derived factor-1alpha is a ligand for both CXC chemokine receptor-4 isoforms. J Immunol. 1997 Apr 15; 158(8):3561-4. PMID: 9103415.
    Citations: 9     Fields:    Translation:AnimalsCells
  103. Farzan M, Choe H, Martin KA, Sun Y, Sidelko M, Mackay CR, Gerard NP, Sodroski J, Gerard C. HIV-1 entry and macrophage inflammatory protein-1beta-mediated signaling are independent functions of the chemokine receptor CCR5. J Biol Chem. 1997 Mar 14; 272(11):6854-7. PMID: 9054370.
    Citations: 69     Fields:    Translation:HumansAnimalsCells
  104. Marcon L, Choe H, Martin KA, Farzan M, Ponath PD, Wu L, Newman W, Gerard N, Gerard C, Sodroski J. Utilization of C-C chemokine receptor 5 by the envelope glycoproteins of a pathogenic simian immunodeficiency virus, SIVmac239. J Virol. 1997 Mar; 71(3):2522-7. PMID: 9032394; PMCID: PMC191367.
    Citations: 61     Fields:    Translation:HumansAnimalsCells
  105. Wu L, Gerard NP, Wyatt R, Choe H, Parolin C, Ruffing N, Borsetti A, Cardoso AA, Desjardin E, Newman W, Gerard C, Sodroski J. CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5. Nature. 1996 Nov 14; 384(6605):179-83. PMID: 8906795.
    Citations: 508     Fields:    Translation:HumansAnimalsCells
  106. Bozic CR, Lu B, Höpken UE, Gerard C, Gerard NP. Neurogenic amplification of immune complex inflammation. Science. 1996 Sep 20; 273(5282):1722-5. PMID: 8781237.
    Citations: 78     Fields:    Translation:AnimalsCells
  107. Höpken UE, Lu B, Gerard NP, Gerard C. The C5a chemoattractant receptor mediates mucosal defence to infection. Nature. 1996 Sep 05; 383(6595):86-9. PMID: 8779720.
    Citations: 131     Fields:    Translation:AnimalsCells
  108. Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath PD, Wu L, Mackay CR, LaRosa G, Newman W, Gerard N, Gerard C, Sodroski J. The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell. 1996 Jun 28; 85(7):1135-48. PMID: 8674119.
    Citations: 806     Fields:    Translation:HumansAnimalsCells
  109. Ponath PD, Qin S, Post TW, Wang J, Wu L, Gerard NP, Newman W, Gerard C, Mackay CR. Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. J Exp Med. 1996 Jun 01; 183(6):2437-48. PMID: 8676064; PMCID: PMC2192612.
    Citations: 137     Fields:    Translation:HumansAnimalsCells
  110. Lu B, Gerard NP, Kolakowski LF, Finco O, Carroll MC, Gerard C. Neutral endopeptidase modulates septic shock. Ann N Y Acad Sci. 1996 Mar 22; 780:156-63. PMID: 8602728.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  111. Gerard N. Rigid fixation of the modified mandibular condylotomy. J Oral Maxillofac Surg. 1996 Mar; 54(3):371-2. PMID: 8600252.
    Citations:    Fields:    Translation:Humans
  112. Bozic CR, Gerard NP, Gerard C. Receptor binding specificity and pulmonary gene expression of the neutrophil-activating peptide ENA-78. Am J Respir Cell Mol Biol. 1996 Mar; 14(3):302-8. PMID: 8845182.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  113. Wang C, Gerard NP, Nicholson-Weller A. Signaling by hemolytically inactive C5b67, an agonist of polymorphonuclear leukocytes. J Immunol. 1996 Jan 15; 156(2):786-92. PMID: 8543834.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  114. Cundell DR, Gerard C, Idanpaan-Heikkila I, Tuomanen EI, Gerard NP. PAf receptor anchors Streptococcus pneumoniae to activated human endothelial cells. Adv Exp Med Biol. 1996; 416:89-94. PMID: 9131132.
    Citations: 18     Fields:    Translation:HumansCells
  115. Post TW, Bozic CR, Rothenberg ME, Luster AD, Gerard N, Gerard C. Molecular characterization of two murine eosinophil beta chemokine receptors. J Immunol. 1995 Dec 01; 155(11):5299-305. PMID: 7594543.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  116. Li C, Chen G, Gerard NP, Gerard C, Bozic CR, Hersh LB. Comparison of the structure and expression of the human and rat neprilysin (endopeptidase 24.11)-encoding genes. Gene. 1995 Oct 27; 164(2):363-6. PMID: 7590358.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  117. García Rodríguez C, Cundell DR, Tuomanen EI, Kolakowski LF, Gerard C, Gerard NP. The role of N-glycosylation for functional expression of the human platelet-activating factor receptor. Glycosylation is required for efficient membrane trafficking. J Biol Chem. 1995 Oct 20; 270(42):25178-84. PMID: 7559653.
    Citations: 12     Fields:    Translation:HumansCells
  118. Cundell DR, Gerard NP, Gerard C, Idanpaan-Heikkila I, Tuomanen EI. Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor. Nature. 1995 Oct 05; 377(6548):435-8. PMID: 7566121.
    Citations: 249     Fields:    Translation:HumansCells
  119. Kolakowski LF, Lu B, Gerard C, Gerard NP. Probing the "message:address" sites for chemoattractant binding to the C5a receptor. Mutagenesis of hydrophilic and proline residues within the transmembrane segments. J Biol Chem. 1995 Jul 28; 270(30):18077-82. PMID: 7629117.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  120. Lu B, Gerard NP, Kolakowski LF, Bozza M, Zurakowski D, Finco O, Carroll MC, Gerard C. Neutral endopeptidase modulation of septic shock. J Exp Med. 1995 Jun 01; 181(6):2271-5. PMID: 7760013; PMCID: PMC2192063.
    Citations: 56     Fields:    Translation:HumansAnimalsCells
  121. Bozic CR, Kolakowski LF, Gerard NP, Garcia-Rodriguez C, von Uexkull-Guldenband C, Conklyn MJ, Breslow R, Showell HJ, Gerard C. Expression and biologic characterization of the murine chemokine KC. J Immunol. 1995 Jun 01; 154(11):6048-57. PMID: 7751647.
    Citations: 108     Fields:    Translation:HumansAnimalsCells
  122. Gerard N, Hendler BH. Laser arthroscopy of the temporomandibular joint. Compend Contin Educ Dent. 1995 Apr; 16(4):350, 352-4; QUIZ 356. PMID: 8935004.
    Citations:    Fields:    Translation:Humans
  123. Bozic CR, Gerard NP, von Uexkull-Guldenband C, Kolakowski LF, Conklyn MJ, Breslow R, Showell HJ, Gerard C. The murine interleukin 8 type B receptor homologue and its ligands. Expression and biological characterization. J Biol Chem. 1994 Nov 25; 269(47):29355-8. PMID: 7961909.
    Citations: 77     Fields:    Translation:HumansAnimalsCells
  124. Gerard C, Gerard NP. The pro-inflammatory seven-transmembrane segment receptors of the leukocyte. Curr Opin Immunol. 1994 Feb; 6(1):140-5. PMID: 8172674.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  125. Jensen CJ, Gerard NP, Schwartz TW, Gether U. The species selectivity of chemically distinct tachykinin nonpeptide antagonists is dependent on common divergent residues of the rat and human neurokinin-1 receptors. Mol Pharmacol. 1994 Feb; 45(2):294-9. PMID: 7509441.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  126. Gerard NP, Gerard C. Receptor-dependent internalization of platelet-activating factor. J Immunol. 1994 Jan 15; 152(2):793-800. PMID: 8283052.
    Citations: 1     Fields:    Translation:HumansCells
  127. Gerard C, Gerard NP. C5A anaphylatoxin and its seven transmembrane-segment receptor. Annu Rev Immunol. 1994; 12:775-808. PMID: 8011297.
    Citations: 88     Fields:    Translation:HumansAnimalsCells
  128. Amatruda TT, Gerard NP, Gerard C, Simon MI. Specific interactions of chemoattractant factor receptors with G-proteins. J Biol Chem. 1993 May 15; 268(14):10139-44. PMID: 8486684.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  129. Gerard NP, Bao L, Xiao-Ping H, Eddy RL, Shows TB, Gerard C. Human chemotaxis receptor genes cluster at 19q13.3-13.4. Characterization of the human C5a receptor gene. Biochemistry. 1993 Feb 09; 32(5):1243-50. PMID: 8383526.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  130. Gerard NP, Bao L, Xiao-Ping H, Gerard C. Molecular aspects of the tachykinin receptors. Regul Pept. 1993 Jan 22; 43(1-2):21-35. PMID: 8381237.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  131. Gerard C, Bao L, Orozco O, Pearson M, Kunz D, Gerard NP. Structural diversity in the extracellular faces of peptidergic G-protein-coupled receptors. Molecular cloning of the mouse C5a anaphylatoxin receptor. J Immunol. 1992 Oct 15; 149(8):2600-6. PMID: 1401897.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  132. Iijima H, Gerard NP, Squassoni C, Ewig J, Face D, Drazen JM, Kim YA, Shriver B, Hersh LB, Gerard C. Exon 16 del: a novel form of human neutral endopeptidase (CALLA). Am J Physiol. 1992 Jun; 262(6 Pt 1):L725-9. PMID: 1535484.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  133. Bao L, Gerard NP, Eddy RL, Shows TB, Gerard C. Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19. Genomics. 1992 Jun; 13(2):437-40. PMID: 1612600.
    Citations: 39     Fields:    Translation:HumansCells
  134. Kunz D, Gerard NP, Gerard C. The human leukocyte platelet-activating factor receptor. cDNA cloning, cell surface expression, and construction of a novel epitope-bearing analog. J Biol Chem. 1992 May 05; 267(13):9101-6. PMID: 1374385.
    Citations: 25     Fields:    Translation:HumansCells
  135. Didsbury JR, Uhing RJ, Tomhave E, Gerard C, Gerard N, Snyderman R. Functional high efficiency expression of cloned leukocyte chemoattractant receptor cDNAs. FEBS Lett. 1992 Feb 10; 297(3):275-9. PMID: 1544408.
    Citations: 7     Fields:    Translation:HumansCells
  136. Didsbury JR, Uhing RJ, Tomhave E, Gerard C, Gerard N, Snyderman R. Receptor class desensitization of leukocyte chemoattractant receptors. Proc Natl Acad Sci U S A. 1991 Dec 15; 88(24):11564-8. PMID: 1763071; PMCID: PMC53176.
    Citations: 26     Fields:    Translation:HumansCells
  137. Gerard NP, Garraway LA, Eddy RL, Shows TB, Iijima H, Paquet JL, Gerard C. Human substance P receptor (NK-1): organization of the gene, chromosome localization, and functional expression of cDNA clones. Biochemistry. 1991 Nov 05; 30(44):10640-6. PMID: 1657150.
    Citations: 38     Fields:    Translation:HumansCells
  138. Himmelfarb J, Gerard NP, Hakim RM. Intradialytic modulation of granulocyte C5a receptors. J Am Soc Nephrol. 1991 Oct; 2(4):920-6. PMID: 1751793.
    Citations: 1     Fields:    Translation:HumansCells
  139. Beckmann MP, Munger WE, Kozlosky C, VandenBos T, Price V, Lyman S, Gerard NP, Gerard C, Cerretti DP. Molecular characterization of the interleukin-8 receptor. Biochem Biophys Res Commun. 1991 Sep 16; 179(2):784-9. PMID: 1898400.
    Citations: 6     Fields:    Translation:AnimalsCells
  140. Wetmore LA, Gerard NP, Herron DK, Bollinger NG, Baker SR, Feldman HA, Drazen JM. Leukotriene receptor on U-937 cells: discriminatory responses to leukotrienes C4 and D4. Am J Physiol. 1991 Aug; 261(2 Pt 1):L164-71. PMID: 1678589.
    Citations: 3     Fields:    Translation:HumansCells
  141. Gerard NP, Gerard C. The chemotactic receptor for human C5a anaphylatoxin. Nature. 1991 Feb 14; 349(6310):614-7. PMID: 1847994.
    Citations: 150     Fields:    Translation:HumansCells
  142. Gerard NP, Eddy RL, Shows TB, Gerard C. The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of the cDNA from tracheal and gastric tissues. J Biol Chem. 1991 Jan 15; 266(2):1354. PMID: 1845990.
    Citations: 4     Fields:    Translation:Cells
  143. Gerard NP, Gerard C. Molecular cloning of the human neurokinin-2 receptor cDNA by polymerase chain reaction and isolation of the gene. Ann N Y Acad Sci. 1991; 632:389-90. PMID: 1659296.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  144. Gerard NP, Eddy RL, Shows TB, Gerard C. The human neurokinin A (substance K) receptor. Molecular cloning of the gene, chromosome localization, and isolation of cDNA from tracheal and gastric tissues. J Biol Chem. 1990 Nov 25; 265(33):20455-62. PMID: 2173708.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  145. Gerard NP, Gerard C. Construction and expression of a novel recombinant anaphylatoxin, C5a-N19, as a probe for the human C5a receptor. Biochemistry. 1990 Oct 02; 29(39):9274-81. PMID: 2271595.
    Citations: 4     Fields:    Translation:HumansCells
  146. Cheng JB, Pillar JS, Conklyn MJ, Breslow R, Shirley JT, Gerard NP, Showell HJ. Antigen-dependent leukotriene synthesis and histamine release from IgG1 passively-sensitized guinea pig lungs ex vivo: relationship between serum levels of antigen-specific IgG1 and mediator synthesis/release. Pulm Pharmacol. 1990; 3(4):171-9. PMID: 1725604.
    Citations:    Fields:    Translation:Animals
  147. Martins MA, Shore SA, Gerard NP, Gerard C, Drazen JM. Peptidase modulation of the pulmonary effects of tachykinins in tracheal superfused guinea pig lungs. J Clin Invest. 1990 Jan; 85(1):170-6. PMID: 1688568; PMCID: PMC296402.
    Citations: 18     Fields:    Translation:Animals
  148. Coats SR, Gerard NP. Characterization of the substance P receptor in guinea pig lung tissues. Am J Respir Cell Mol Biol. 1989 Oct; 1(4):269-75. PMID: 2483120.
    Citations: 1     Fields:    Translation:AnimalsCells
  149. Cholin S, Gerard NP, Strang CJ, Davis AE. Biologic activity of a C2-derived peptide. Demonstration of a specific interaction with guinea pig lung tissues. J Immunol. 1989 Apr 01; 142(7):2401-4. PMID: 2926138.
    Citations: 1     Fields:    Translation:AnimalsCells
  150. Drazen JM, Shore SA, Gerard NP. Substance P-induced effects in guinea pig lungs: effects of thiorphan and captopril. J Appl Physiol (1985). 1989 Mar; 66(3):1364-72. PMID: 2468641.
    Citations: 2     Fields:    Translation:Animals
  151. Gerard NP, Hodges MK, Drazen JM, Weller PF, Gerard C. Characterization of a receptor for C5a anaphylatoxin on human eosinophils. J Biol Chem. 1989 Jan 25; 264(3):1760-6. PMID: 2912983.
    Citations: 36     Fields:    Translation:HumansCells
  152. Drazen JM, Shore SA, Gerard NP. Enzymatic degradation of neuropeptides: a possible mechanism of airway hyperresponsiveness. Prog Clin Biol Res. 1989; 297:45-55; discussion 55-6. PMID: 2479951.
    Citations: 1     Fields:    Translation:HumansAnimals
  153. Gerard C, Bhaskar KR, Gerard NP, Drazen JM, Reid L. Studies on the peptide core of human bronchial mucus glycoprotein. Symp Soc Exp Biol. 1989; 43:221-30. PMID: 2701478.
    Citations:    Fields:    Translation:HumansAnimalsCells
  154. Hodges MK, Weller PF, Gerard NP, Ackerman SJ, Drazen JM. Heterogeneity of leukotriene C4 production by eosinophils from asthmatic and from normal subjects. Am Rev Respir Dis. 1988 Oct; 138(4):799-804. PMID: 3144208.
    Citations: 7     Fields:    Translation:HumansCells
  155. Martin TR, Gerard NP, Galli SJ, Drazen JM. Pulmonary responses to bronchoconstrictor agonists in the mouse. J Appl Physiol (1985). 1988 Jun; 64(6):2318-23. PMID: 2457008.
    Citations: 78     Fields:    Translation:Animals
  156. Gerard NP, Lively MO, Gerard C. Amino acid sequence of guinea pig C3a anaphylatoxin. Protein Seq Data Anal. 1988; 1(6):473-8. PMID: 3064079.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  157. Gerard NP. Characterization of substance P contractile activity on isolated guinea pig lung tissues. J Pharmacol Exp Ther. 1987 Dec; 243(3):901-6. PMID: 2447271.
    Citations: 3     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.