Harvard Catalyst Profiles

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Stephen Buratowski, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01CA246500 (BURATOWSKI, STEPHEN) Feb 7, 2020 - Jan 31, 2024
    Single-molecule analysis of eukaryotic transcription activation
    Role: Principal Investigator
  2. R01GM056663 (BURATOWSKI, STEPHEN) Jul 1, 1999 - Jun 30, 2019
    mRNA Capping Enzyme
    Role: Principal Investigator
  3. R01GM046498 (BURATOWSKI, STEPHEN) Jul 6, 1991 - Mar 31, 2021
    The RNA polymerase II transcription complex
    Role: Principal Investigator
  4. R29GM046498 (BURATOWSKI, STEPHEN) Jul 6, 1991 - Jun 30, 1996
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Bae HJ, Dubarry M, Jeon J, Soares LM, Dargemont C, Kim J, Geli V, Buratowski S. The Set1 N-terminal domain and Swd2 interact with RNA polymerase II CTD to recruit COMPASS. Nat Commun. 2020 May 01; 11(1):2181. PMID: 32358498.
  2. Chun Y, Joo YJ, Suh H, Batot G, Hill CP, Formosa T, Buratowski S. Selective Kinase Inhibition Shows That Bur1 (Cdk9) Phosphorylates the Rpb1 Linker In Vivo. Mol Cell Biol. 2019 08 01; 39(15). PMID: 31085683.
  3. Zhang Y, Chun Y, Buratowski S, Tong L. Identification of Three Sequence Motifs in the Transcription Termination Factor Sen1 that Mediate Direct Interactions with Nrd1. Structure. 2019 07 02; 27(7):1156-1161.e4. PMID: 31104813.
  4. Joo YJ, Ficarro SB, Chun Y, Marto JA, Buratowski S. In vitro analysis of RNA polymerase II elongation complex dynamics. Genes Dev. 2019 05 01; 33(9-10):578-589. PMID: 30846429.
  5. Joo YJ, Ficarro SB, Marto JA, Buratowski S. In vitro assembly and proteomic analysis of RNA polymerase II complexes. Methods. 2019 04 15; 159-160:96-104. PMID: 30844430.
  6. Neurohr GE, Terry RL, Lengefeld J, Bonney M, Brittingham GP, Moretto F, Miettinen TP, Vaites LP, Soares LM, Paulo JA, Harper JW, Buratowski S, Manalis S, van Werven FJ, Holt LJ, Amon A. Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence. Cell. 2019 02 21; 176(5):1083-1097.e18. PMID: 30739799.
  7. Oliete-Calvo P, Serrano-Quílez J, Nuño-Cabanes C, Pérez-Martínez ME, Soares LM, Dichtl B, Buratowski S, Pérez-Ortín JE, Rodríguez-Navarro S. A role for Mog1 in H2Bub1 and H3K4me3 regulation affecting RNAPII transcription and mRNA export. EMBO Rep. 2018 11; 19(11). PMID: 30249596.
    Citations:    Fields:    
  8. Lee BB, Choi A, Kim JH, Jun Y, Woo H, Ha SD, Yoon CY, Hwang JT, Steinmetz L, Buratowski S, Lee S, Kim HY, Kim T. Rpd3L HDAC links H3K4me3 to transcriptional repression memory. Nucleic Acids Res. 2018 09 19; 46(16):8261-8274. PMID: 29982589.
    Citations:    Fields:    
  9. Mischo HE, Chun Y, Harlen KM, Smalec BM, Dhir S, Churchman LS, Buratowski S. Cell-Cycle Modulation of Transcription Termination Factor Sen1. Mol Cell. 2018 04 19; 70(2):312-326.e7. PMID: 29656924.
    Citations:    Fields:    
  10. du Mee DJM, Ivanov M, Parker JP, Buratowski S, Marquardt S. Efficient termination of nuclear lncRNA transcription promotes mitochondrial genome maintenance. Elife. 2018 03 05; 7. PMID: 29504936.
    Citations:    Fields:    
  11. Kim JH, Lee BB, Oh YM, Zhu C, Steinmetz LM, Lee Y, Kim WK, Lee SB, Buratowski S, Kim T. Erratum: Modulation of mRNA and lncRNA expression dynamics by the Set2-Rpd3S pathway. Nat Commun. 2017 11 29; 8:16122. PMID: 29184145.
    Citations: 1     Fields:    
  12. Soares LM, He PC, Chun Y, Suh H, Kim T, Buratowski S. Determinants of Histone H3K4 Methylation Patterns. Mol Cell. 2017 Nov 16; 68(4):773-785.e6. PMID: 29129639.
    Citations: 3     Fields:    Translation:AnimalsCells
  13. Joo YJ, Ficarro SB, Soares LM, Chun Y, Marto JA, Buratowski S. Downstream promoter interactions of TFIID TAFs facilitate transcription reinitiation. Genes Dev. 2017 11 01; 31(21):2162-2174. PMID: 29203645.
    Citations:    Fields:    Translation:AnimalsCells
  14. Church VA, Pressman S, Isaji M, Truscott M, Cizmecioglu NT, Buratowski S, Frolov MV, Carthew RW. Microprocessor Recruitment to Elongating RNA Polymerase II Is Required for Differential Expression of MicroRNAs. Cell Rep. 2017 Sep 26; 20(13):3123-3134. PMID: 28954229.
    Citations: 3     Fields:    Translation:Humans
  15. Woo H, Dam Ha S, Lee SB, Buratowski S, Kim T. Modulation of gene expression dynamics by co-transcriptional histone methylations. Exp Mol Med. 2017 04 28; 49(4):e326. PMID: 28450734.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  16. Kim JH, Lee BB, Oh YM, Zhu C, Steinmetz LM, Lee Y, Kim WK, Lee SB, Buratowski S, Kim T. Modulation of mRNA and lncRNA expression dynamics by the Set2-Rpd3S pathway. Nat Commun. 2016 11 28; 7:13534. PMID: 27892458.
    Citations: 17     Fields:    Translation:AnimalsCells
  17. Hahn S, Buratowski S. Structural biology: Snapshots of transcription initiation. Nature. 2016 05 19; 533(7603):331-2. PMID: 27193677.
    Citations: 2     Fields:    Translation:HumansCells
  18. Suh H, Ficarro SB, Kang UB, Chun Y, Marto JA, Buratowski S. Direct Analysis of Phosphorylation Sites on the Rpb1 C-Terminal Domain of RNA Polymerase II. Mol Cell. 2016 Jan 21; 61(2):297-304. PMID: 26799764.
    Citations: 25     Fields:    Translation:AnimalsCells
  19. Marquardt S, Escalante-Chong R, Pho N, Wang J, Churchman LS, Springer M, Buratowski S. A Chromatin-Based Mechanism for Limiting Divergent Noncoding Transcription. Cell. 2014 Jul 17; 158(2):462. PMID: 28915368.
    Citations:    Fields:    
  20. Marquardt S, Escalante-Chong R, Pho N, Wang J, Churchman LS, Springer M, Buratowski S. A chromatin-based mechanism for limiting divergent noncoding transcription. Cell. 2014 Jun 19; 157(7):1712-23. PMID: 24949978.
    Citations: 37     Fields:    Translation:AnimalsCells
  21. Soares LM, Radman-Livaja M, Lin SG, Rando OJ, Buratowski S. Feedback control of Set1 protein levels is important for proper H3K4 methylation patterns. Cell Rep. 2014 Mar 27; 6(6):961-972. PMID: 24613354.
    Citations: 14     Fields:    Translation:AnimalsCells
  22. Heo DH, Yoo I, Kong J, Lidschreiber M, Mayer A, Choi BY, Hahn Y, Cramer P, Buratowski S, Kim M. The RNA polymerase II C-terminal domain-interacting domain of yeast Nrd1 contributes to the choice of termination pathway and couples to RNA processing by the nuclear exosome. J Biol Chem. 2013 Dec 20; 288(51):36676-90. PMID: 24196955.
    Citations: 7     Fields:    Translation:AnimalsCells
  23. Suh H, Hazelbaker DZ, Soares LM, Buratowski S. The C-terminal domain of Rpb1 functions on other RNA polymerase II subunits. Mol Cell. 2013 Sep 26; 51(6):850-8. PMID: 24035501.
    Citations: 6     Fields:    Translation:AnimalsCells
  24. Soares LM, Buratowski S. Histone Crosstalk: H2Bub and H3K4 Methylation. Mol Cell. 2013 Mar 28; 49(6):1019-20. PMID: 23541037.
    Citations: 9     Fields:    
  25. Fowler T, Suh H, Buratowski S, Roy AL. Regulation of primary response genes in B cells. J Biol Chem. 2013 May 24; 288(21):14906-16. PMID: 23536186.
    Citations: 3     Fields:    Translation:AnimalsCells
  26. Hazelbaker DZ, Marquardt S, Wlotzka W, Buratowski S. Kinetic competition between RNA Polymerase II and Sen1-dependent transcription termination. Mol Cell. 2013 Jan 10; 49(1):55-66. PMID: 23177741.
    Citations: 42     Fields:    Translation:AnimalsCells
  27. Hazelbaker DZ, Buratowski S. Transcription: base J blocks the way. Curr Biol. 2012 Nov 20; 22(22):R960-2. PMID: 23174300.
    Citations:    Fields:    Translation:AnimalsCells
  28. van Werven FJ, Neuert G, Hendrick N, Lardenois A, Buratowski S, van Oudenaarden A, Primig M, Amon A. Transcription of two long noncoding RNAs mediates mating-type control of gametogenesis in budding yeast. Cell. 2012 Sep 14; 150(6):1170-81. PMID: 22959267.
    Citations: 82     Fields:    Translation:AnimalsCells
  29. Kim T, Xu Z, Clauder-Münster S, Steinmetz LM, Buratowski S. Set3 HDAC mediates effects of overlapping noncoding transcription on gene induction kinetics. Cell. 2012 Sep 14; 150(6):1158-69. PMID: 22959268.
    Citations: 73     Fields:    Translation:AnimalsCells
  30. Sikorski TW, Joo YJ, Ficarro SB, Askenazi M, Buratowski S, Marto JA. Proteomic analysis demonstrates activator- and chromatin-specific recruitment to promoters. J Biol Chem. 2012 Oct 12; 287(42):35397-408. PMID: 22902623.
    Citations: 9     Fields:    Translation:AnimalsCells
  31. Weiner A, Chen HV, Liu CL, Rahat A, Klien A, Soares L, Gudipati M, Pfeffner J, Regev A, Buratowski S, Pleiss JA, Friedman N, Rando OJ. Systematic dissection of roles for chromatin regulators in a yeast stress response. PLoS Biol. 2012; 10(7):e1001369. PMID: 22912562.
    Citations: 61     Fields:    Translation:AnimalsCells
  32. Radman-Livaja M, Quan TK, Valenzuela L, Armstrong JA, van Welsem T, Kim T, Lee LJ, Buratowski S, van Leeuwen F, Rando OJ, Hartzog GA. A key role for Chd1 in histone H3 dynamics at the 3' ends of long genes in yeast. PLoS Genet. 2012; 8(7):e1002811. PMID: 22807688.
    Citations: 30     Fields:    Translation:AnimalsCells
  33. Soares LM, Buratowski S. Yeast Swd2 is essential because of antagonism between Set1 histone methyltransferase complex and APT (associated with Pta1) termination factor. J Biol Chem. 2012 May 04; 287(19):15219-31. PMID: 22431730.
    Citations: 19     Fields:    Translation:AnimalsCells
  34. Buratowski S. Gene expression: transcription initiation unwrapped. Nature. 2012 Mar 14; 483(7389):286-7. PMID: 22422261.
    Citations: 1     Fields:    Translation:AnimalsCells
  35. Sikorski TW, Ficarro SB, Holik J, Kim T, Rando OJ, Marto JA, Buratowski S. Sub1 and RPA associate with RNA polymerase II at different stages of transcription. Mol Cell. 2011 Nov 04; 44(3):397-409. PMID: 22055186.
    Citations: 32     Fields:    Translation:AnimalsCells
  36. Terzi N, Churchman LS, Vasiljeva L, Weissman J, Buratowski S. H3K4 trimethylation by Set1 promotes efficient termination by the Nrd1-Nab3-Sen1 pathway. Mol Cell Biol. 2011 Sep; 31(17):3569-83. PMID: 21709022.
    Citations: 30     Fields:    Translation:Cells
  37. Lenstra TL, Benschop JJ, Kim T, Schulze JM, Brabers NA, Margaritis T, van de Pasch LA, van Heesch SA, Brok MO, Groot Koerkamp MJ, Ko CW, van Leenen D, Sameith K, van Hooff SR, Lijnzaad P, Kemmeren P, Hentrich T, Kobor MS, Buratowski S, Holstege FC. The specificity and topology of chromatin interaction pathways in yeast. Mol Cell. 2011 May 20; 42(4):536-49. PMID: 21596317.
    Citations: 92     Fields:    Translation:AnimalsCells
  38. Marquardt S, Hazelbaker DZ, Buratowski S. Distinct RNA degradation pathways and 3' extensions of yeast non-coding RNA species. Transcription. 2011 May; 2(3):145-154. PMID: 21826286.
    Citations: 35     Fields:    
  39. Buratowski S, Kim T. The role of cotranscriptional histone methylations. Cold Spring Harb Symp Quant Biol. 2010; 75:95-102. PMID: 21447819.
    Citations: 25     Fields:    Translation:AnimalsCells
  40. Lunde BM, Reichow SL, Kim M, Suh H, Leeper TC, Yang F, Mutschler H, Buratowski S, Meinhart A, Varani G. Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain. Nat Struct Mol Biol. 2010 Oct; 17(10):1195-201. PMID: 20818393.
    Citations: 51     Fields:    Translation:HumansCells
  41. Dermody JL, Buratowski S. Leo1 subunit of the yeast paf1 complex binds RNA and contributes to complex recruitment. J Biol Chem. 2010 Oct 29; 285(44):33671-9. PMID: 20732871.
    Citations: 20     Fields:    Translation:AnimalsCells
  42. Kim TS, Liu CL, Yassour M, Holik J, Friedman N, Buratowski S, Rando OJ. RNA polymerase mapping during stress responses reveals widespread nonproductive transcription in yeast. Genome Biol. 2010; 11(7):R75. PMID: 20637075.
    Citations: 26     Fields:    Translation:AnimalsCells
  43. Buratowski S. Progression through the RNA polymerase II CTD cycle. Mol Cell. 2009 Nov 25; 36(4):541-6. PMID: 19941815.
    Citations: 307     Fields:    Translation:HumansAnimalsCells
  44. Johnson A, Li G, Sikorski TW, Buratowski S, Woodcock CL, Moazed D. Reconstitution of heterochromatin-dependent transcriptional gene silencing. Mol Cell. 2009 Sep 24; 35(6):769-81. PMID: 19782027.
    Citations: 40     Fields:    Translation:AnimalsCells
  45. Kim M, Suh H, Cho EJ, Buratowski S. Phosphorylation of the yeast Rpb1 C-terminal domain at serines 2, 5, and 7. J Biol Chem. 2009 Sep 25; 284(39):26421-6. PMID: 19679665.
    Citations: 63     Fields:    Translation:AnimalsCells
  46. Sikorski TW, Buratowski S. The basal initiation machinery: beyond the general transcription factors. Curr Opin Cell Biol. 2009 Jun; 21(3):344-51. PMID: 19411170.
    Citations: 75     Fields:    Translation:HumansCells
  47. Kim T, Buratowski S. Dimethylation of H3K4 by Set1 recruits the Set3 histone deacetylase complex to 5' transcribed regions. Cell. 2009 Apr 17; 137(2):259-72. PMID: 19379692.
    Citations: 127     Fields:    Translation:AnimalsCells
  48. Ahn SH, Keogh MC, Buratowski S. Ctk1 promotes dissociation of basal transcription factors from elongating RNA polymerase II. EMBO J. 2009 Feb 04; 28(3):205-12. PMID: 19131970.
    Citations: 24     Fields:    Translation:AnimalsCells
  49. Buratowski S. Transcription. Gene expression--where to start? Science. 2008 Dec 19; 322(5909):1804-5. PMID: 19095933.
    Citations: 26     Fields:    Translation:Cells
  50. Dermody JL, Dreyfuss JM, Villén J, Ogundipe B, Gygi SP, Park PJ, Ponticelli AS, Moore CL, Buratowski S, Bucheli ME. Unphosphorylated SR-like protein Npl3 stimulates RNA polymerase II elongation. PLoS One. 2008 Sep 26; 3(9):e3273. PMID: 18818768.
    Citations: 33     Fields:    Translation:AnimalsCells
  51. Vasiljeva L, Kim M, Mutschler H, Buratowski S, Meinhart A. The Nrd1-Nab3-Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain. Nat Struct Mol Biol. 2008 Aug; 15(8):795-804. PMID: 18660819.
    Citations: 128     Fields:    Translation:AnimalsCells
  52. Vasiljeva L, Kim M, Terzi N, Soares LM, Buratowski S. Transcription termination and RNA degradation contribute to silencing of RNA polymerase II transcription within heterochromatin. Mol Cell. 2008 Feb 15; 29(3):313-23. PMID: 18280237.
    Citations: 65     Fields:    Translation:AnimalsCells
  53. Runner VM, Podolny V, Buratowski S. The Rpb4 subunit of RNA polymerase II contributes to cotranscriptional recruitment of 3' processing factors. Mol Cell Biol. 2008 Mar; 28(6):1883-91. PMID: 18195044.
    Citations: 35     Fields:    Translation:Cells
  54. Deka P, Bucheli ME, Moore C, Buratowski S, Varani G. Structure of the yeast SR protein Npl3 and Interaction with mRNA 3'-end processing signals. J Mol Biol. 2008 Jan 04; 375(1):136-50. PMID: 18022637.
    Citations: 14     Fields:    Translation:AnimalsCells
  55. Bucheli ME, He X, Kaplan CD, Moore CL, Buratowski S. Polyadenylation site choice in yeast is affected by competition between Npl3 and polyadenylation factor CFI. RNA. 2007 Oct; 13(10):1756-64. PMID: 17684230.
    Citations: 31     Fields:    Translation:AnimalsCells
  56. Huarte M, Lan F, Kim T, Vaughn MW, Zaratiegui M, Martienssen RA, Buratowski S, Shi Y. The fission yeast Jmj2 reverses histone H3 Lysine 4 trimethylation. J Biol Chem. 2007 Jul 27; 282(30):21662-70. PMID: 17550896.
    Citations: 15     Fields:    Translation:AnimalsCells
  57. Kim T, Buratowski S. Two Saccharomyces cerevisiae JmjC domain proteins demethylate histone H3 Lys36 in transcribed regions to promote elongation. J Biol Chem. 2007 Jul 20; 282(29):20827-35. PMID: 17525156.
    Citations: 29     Fields:    Translation:AnimalsCells
  58. Dion MF, Kaplan T, Kim M, Buratowski S, Friedman N, Rando OJ. Dynamics of replication-independent histone turnover in budding yeast. Science. 2007 Mar 09; 315(5817):1405-8. PMID: 17347438.
    Citations: 266     Fields:    Translation:AnimalsCells
  59. Kim M, Vasiljeva L, Rando OJ, Zhelkovsky A, Moore C, Buratowski S. Distinct pathways for snoRNA and mRNA termination. Mol Cell. 2006 Dec 08; 24(5):723-734. PMID: 17157255.
    Citations: 92     Fields:    Translation:AnimalsCells
  60. Voynov V, Verstrepen KJ, Jansen A, Runner VM, Buratowski S, Fink GR. Genes with internal repeats require the THO complex for transcription. Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39):14423-8. PMID: 16983072.
    Citations: 26     Fields:    Translation:AnimalsCells
  61. Keogh MC, Mennella TA, Sawa C, Berthelet S, Krogan NJ, Wolek A, Podolny V, Carpenter LR, Greenblatt JF, Baetz K, Buratowski S. The Saccharomyces cerevisiae histone H2A variant Htz1 is acetylated by NuA4. Genes Dev. 2006 Mar 15; 20(6):660-5. PMID: 16543219.
    Citations: 104     Fields:    Translation:AnimalsCells
  62. Vasiljeva L, Buratowski S. Nrd1 interacts with the nuclear exosome for 3' processing of RNA polymerase II transcripts. Mol Cell. 2006 Jan 20; 21(2):239-48. PMID: 16427013.
    Citations: 120     Fields:    Translation:AnimalsCells
  63. Chowdhury D, Keogh MC, Ishii H, Peterson CL, Buratowski S, Lieberman J. gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair. Mol Cell. 2005 Dec 09; 20(5):801-9. PMID: 16310392.
    Citations: 159     Fields:    Translation:HumansAnimalsCells
  64. Keogh MC, Kim JA, Downey M, Fillingham J, Chowdhury D, Harrison JC, Onishi M, Datta N, Galicia S, Emili A, Lieberman J, Shen X, Buratowski S, Haber JE, Durocher D, Greenblatt JF, Krogan NJ. A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recovery. Nature. 2006 Jan 26; 439(7075):497-501. PMID: 16299494.
    Citations: 179     Fields:    Translation:AnimalsCells
  65. Keogh MC, Kurdistani SK, Morris SA, Ahn SH, Podolny V, Collins SR, Schuldiner M, Chin K, Punna T, Thompson NJ, Boone C, Emili A, Weissman JS, Hughes TR, Strahl BD, Grunstein M, Greenblatt JF, Buratowski S, Krogan NJ. Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex. Cell. 2005 Nov 18; 123(4):593-605. PMID: 16286008.
    Citations: 355     Fields:    Translation:AnimalsCells
  66. Liu CL, Kaplan T, Kim M, Buratowski S, Schreiber SL, Friedman N, Rando OJ. Single-nucleosome mapping of histone modifications in S. cerevisiae. PLoS Biol. 2005 Oct; 3(10):e328. PMID: 16122352.
    Citations: 235     Fields:    Translation:AnimalsCells
  67. Buratowski S, Moazed D. Gene regulation: expression and silencing coupled. Nature. 2005 Jun 30; 435(7046):1174-5. PMID: 15988510.
    Citations: 2     Fields:    Translation:AnimalsCells
  68. Buratowski S. Connections between mRNA 3' end processing and transcription termination. Curr Opin Cell Biol. 2005 Jun; 17(3):257-61. PMID: 15901494.
    Citations: 88     Fields:    Translation:HumansAnimalsCells
  69. Bucheli ME, Buratowski S. Npl3 is an antagonist of mRNA 3' end formation by RNA polymerase II. EMBO J. 2005 Jun 15; 24(12):2150-60. PMID: 15902270.
    Citations: 41     Fields:    Translation:AnimalsCells
  70. Krogan NJ, Lam MH, Fillingham J, Keogh MC, Gebbia M, Li J, Datta N, Cagney G, Buratowski S, Emili A, Greenblatt JF. Proteasome involvement in the repair of DNA double-strand breaks. Mol Cell. 2004 Dec 22; 16(6):1027-34. PMID: 15610744.
    Citations: 82     Fields:    Translation:AnimalsCells
  71. Kim M, Krogan NJ, Vasiljeva L, Rando OJ, Nedea E, Greenblatt JF, Buratowski S. The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II. Nature. 2004 Nov 25; 432(7016):517-22. PMID: 15565157.
    Citations: 188     Fields:    Translation:AnimalsCells
  72. Auty R, Steen H, Myers LC, Persinger J, Bartholomew B, Gygi SP, Buratowski S. Purification of active TFIID from Saccharomyces cerevisiae. Extensive promoter contacts and co-activator function. J Biol Chem. 2004 Nov 26; 279(48):49973-81. PMID: 15448131.
    Citations: 16     Fields:    Translation:AnimalsCells
  73. Krogan NJ, Baetz K, Keogh MC, Datta N, Sawa C, Kwok TC, Thompson NJ, Davey MG, Pootoolal J, Hughes TR, Emili A, Buratowski S, Hieter P, Greenblatt JF. Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4. Proc Natl Acad Sci U S A. 2004 Sep 14; 101(37):13513-8. PMID: 15353583.
    Citations: 102     Fields:    Translation:AnimalsCells
  74. Sawa C, Nedea E, Krogan N, Wada T, Handa H, Greenblatt J, Buratowski S. Bromodomain factor 1 (Bdf1) is phosphorylated by protein kinase CK2. Mol Cell Biol. 2004 Jun; 24(11):4734-42. PMID: 15143168.
    Citations: 16     Fields:    Translation:AnimalsCells
  75. Kim M, Ahn SH, Krogan NJ, Greenblatt JF, Buratowski S. Transitions in RNA polymerase II elongation complexes at the 3' ends of genes. EMBO J. 2004 Jan 28; 23(2):354-64. PMID: 14739930.
    Citations: 152     Fields:    Translation:Cells
  76. Ahn SH, Kim M, Buratowski S. Phosphorylation of serine 2 within the RNA polymerase II C-terminal domain couples transcription and 3' end processing. Mol Cell. 2004 Jan 16; 13(1):67-76. PMID: 14731395.
    Citations: 214     Fields:    Translation:AnimalsCells
  77. Keogh MC, Buratowski S. Using chromatin immunoprecipitation to map cotranscriptional mRNA processing in Saccharomyces cerevisiae. Methods Mol Biol. 2004; 257:1-16. PMID: 14769992.
    Citations: 27     Fields:    Translation:AnimalsCells
  78. Matangkasombut O, Auty R, Buratowski S. Structure and function of the TFIID complex. Adv Protein Chem. 2004; 67:67-92. PMID: 14969724.
    Citations: 25     Fields:    Translation:HumansCells
  79. Krogan NJ, Keogh MC, Datta N, Sawa C, Ryan OW, Ding H, Haw RA, Pootoolal J, Tong A, Canadien V, Richards DP, Wu X, Emili A, Hughes TR, Buratowski S, Greenblatt JF. A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell. 2003 Dec; 12(6):1565-76. PMID: 14690608.
    Citations: 231     Fields:    Translation:HumansAnimalsCells
  80. Keogh MC, Podolny V, Buratowski S. Bur1 kinase is required for efficient transcription elongation by RNA polymerase II. Mol Cell Biol. 2003 Oct; 23(19):7005-18. PMID: 12972617.
    Citations: 74     Fields:    Translation:Cells
  81. Buratowski S. The CTD code. Nat Struct Biol. 2003 Sep; 10(9):679-80. PMID: 12942140.
    Citations: 123     Fields:    Translation:AnimalsCells
  82. Nedea E, He X, Kim M, Pootoolal J, Zhong G, Canadien V, Hughes T, Buratowski S, Moore CL, Greenblatt J. Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends. J Biol Chem. 2003 Aug 29; 278(35):33000-10. PMID: 12819204.
    Citations: 83     Fields:    Translation:AnimalsCells
  83. Krogan NJ, Kim M, Tong A, Golshani A, Cagney G, Canadien V, Richards DP, Beattie BK, Emili A, Boone C, Shilatifard A, Buratowski S, Greenblatt J. Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II. Mol Cell Biol. 2003 Jun; 23(12):4207-18. PMID: 12773564.
    Citations: 272     Fields:    Translation:AnimalsCells
  84. Takagi T, Walker AK, Sawa C, Diehn F, Takase Y, Blackwell TK, Buratowski S. The Caenorhabditis elegans mRNA 5'-capping enzyme. In vitro and in vivo characterization. J Biol Chem. 2003 Apr 18; 278(16):14174-84. PMID: 12576476.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  85. Matangkasombut O, Buratowski S. Different sensitivities of bromodomain factors 1 and 2 to histone H4 acetylation. Mol Cell. 2003 Feb; 11(2):353-63. PMID: 12620224.
    Citations: 75     Fields:    Translation:AnimalsCells
  86. Buratowski RM, Downs J, Buratowski S. Interdependent interactions between TFIIB, TATA binding protein, and DNA. Mol Cell Biol. 2002 Dec; 22(24):8735-43. PMID: 12446790.
    Citations: 7     Fields:    Translation:AnimalsCells
  87. Krogan NJ, Kim M, Ahn SH, Zhong G, Kobor MS, Cagney G, Emili A, Shilatifard A, Buratowski S, Greenblatt JF. RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach. Mol Cell Biol. 2002 Oct; 22(20):6979-92. PMID: 12242279.
    Citations: 215     Fields:    Translation:AnimalsCells
  88. Takagi T, Cho EJ, Janoo RT, Polodny V, Takase Y, Keogh MC, Woo SA, Fresco-Cohen LD, Hoffman CS, Buratowski S. Divergent subunit interactions among fungal mRNA 5'-capping machineries. Eukaryot Cell. 2002 Jun; 1(3):448-57. PMID: 12455993.
    Citations: 6     Fields:    Translation:AnimalsCells
  89. Keogh MC, Cho EJ, Podolny V, Buratowski S. Kin28 is found within TFIIH and a Kin28-Ccl1-Tfb3 trimer complex with differential sensitivities to T-loop phosphorylation. Mol Cell Biol. 2002 Mar; 22(5):1288-97. PMID: 11839796.
    Citations: 31     Fields:    Translation:AnimalsCells
  90. Cho EJ, Kobor MS, Kim M, Greenblatt J, Buratowski S. Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain. Genes Dev. 2001 Dec 15; 15(24):3319-29. PMID: 11751637.
    Citations: 172     Fields:    Translation:AnimalsCells
  91. Selleck W, Howley R, Fang Q, Podolny V, Fried MG, Buratowski S, Tan S. A histone fold TAF octamer within the yeast TFIID transcriptional coactivator. Nat Struct Biol. 2001 Aug; 8(8):695-700. PMID: 11473260.
    Citations: 28     Fields:    Translation:AnimalsCells
  92. Buratowski S, Chodosh LA. Mobility shift DNA-binding assay using gel electrophoresis. Curr Protoc Pharmacol. 2001 Aug; Chapter 6:Unit6.8. PMID: 21959763.
    Citations: 1     Fields:    Translation:Cells
  93. Buratowski S, Chodosh LA. Mobility shift DNA-binding assay using gel electrophoresis. Curr Protoc Mol Biol. 2001 May; Chapter 12:Unit 12.2. PMID: 18265085.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  94. Chodosh LA, Buratowski S. Purification of DNA-binding proteins using biotin/streptavidin affinity systems. Curr Protoc Protein Sci. 2001 May; Chapter 9:Unit 9.7. PMID: 18429216.
    Citations:    Fields:    Translation:Cells
  95. Takagi T, Buratowski S. A Plasmodium falciparum protein related to fungal RNA 5'-triphosphatases. Mol Biochem Parasitol. 2001 May; 114(2):239-44. PMID: 11378203.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  96. Takase Y, Takagi T, Komarnitsky PB, Buratowski S. The essential interaction between yeast mRNA capping enzyme subunits is not required for triphosphatase function in vivo. Mol Cell Biol. 2000 Dec; 20(24):9307-16. PMID: 11094081.
    Citations: 9     Fields:    Translation:AnimalsCells
  97. Komarnitsky P, Cho EJ, Buratowski S. Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription. Genes Dev. 2000 Oct 01; 14(19):2452-60. PMID: 11018013.
    Citations: 448     Fields:    Translation:AnimalsCells
  98. Buratowski S. Snapshots of RNA polymerase II transcription initiation. Curr Opin Cell Biol. 2000 Jun; 12(3):320-5. PMID: 10801469.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  99. Matangkasombut O, Buratowski RM, Swilling NW, Buratowski S. Bromodomain factor 1 corresponds to a missing piece of yeast TFIID. Genes Dev. 2000 Apr 15; 14(8):951-62. PMID: 10783167.
    Citations: 75     Fields:    Translation:AnimalsCells
  100. Rodriguez CR, Cho EJ, Keogh MC, Moore CL, Greenleaf AL, Buratowski S. Kin28, the TFIIH-associated carboxy-terminal domain kinase, facilitates the recruitment of mRNA processing machinery to RNA polymerase II. Mol Cell Biol. 2000 Jan; 20(1):104-12. PMID: 10594013.
    Citations: 82     Fields:    Translation:AnimalsCells
  101. Morehouse H, Buratowski RM, Silver PA, Buratowski S. The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12542-7. PMID: 10535958.
    Citations: 20     Fields:    Translation:Cells
  102. Komarnitsky PB, Michel B, Buratowski S. TFIID-specific yeast TAF40 is essential for the majority of RNA polymerase II-mediated transcription in vivo. Genes Dev. 1999 Oct 01; 13(19):2484-9. PMID: 10521393.
    Citations: 25     Fields:    Translation:AnimalsCells
  103. Cho EJ, Buratowski S. Evidence that transcription factor IIB is required for a post-assembly step in transcription initiation. J Biol Chem. 1999 Sep 03; 274(36):25807-13. PMID: 10464320.
    Citations: 32     Fields:    Translation:AnimalsCells
  104. Deshpande T, Takagi T, Hao L, Buratowski S, Charbonneau H. Human PIR1 of the protein-tyrosine phosphatase superfamily has RNA 5'-triphosphatase and diphosphatase activities. J Biol Chem. 1999 Jun 04; 274(23):16590-4. PMID: 10347225.
    Citations: 11     Fields:    Translation:HumansCells
  105. Rodriguez CR, Takagi T, Cho EJ, Buratowski S. A Saccharomyces cerevisiae RNA 5'-triphosphatase related to mRNA capping enzyme. Nucleic Acids Res. 1999 May 15; 27(10):2181-8. PMID: 10219091.
    Citations: 17     Fields:    Translation:AnimalsCells
  106. Cho EJ, Rodriguez CR, Takagi T, Buratowski S. Allosteric interactions between capping enzyme subunits and the RNA polymerase II carboxy-terminal domain. Genes Dev. 1998 Nov 15; 12(22):3482-7. PMID: 9832501.
    Citations: 37     Fields:    Translation:AnimalsCells
  107. Michel B, Komarnitsky P, Buratowski S. Histone-like TAFs are essential for transcription in vivo. Mol Cell. 1998 Nov; 2(5):663-73. PMID: 9844638.
    Citations: 39     Fields:    Translation:AnimalsCells
  108. Takagi T, Taylor GS, Kusakabe T, Charbonneau H, Buratowski S. A protein tyrosine phosphatase-like protein from baculovirus has RNA 5'-triphosphatase and diphosphatase activities. Proc Natl Acad Sci U S A. 1998 Aug 18; 95(17):9808-12. PMID: 9707557.
    Citations: 10     Fields:    Translation:AnimalsCells
  109. Wada T, Takagi T, Yamaguchi Y, Ferdous A, Imai T, Hirose S, Sugimoto S, Yano K, Hartzog GA, Winston F, Buratowski S, Handa H. DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs. Genes Dev. 1998 Feb 01; 12(3):343-56. PMID: 9450929.
    Citations: 282     Fields:    Translation:HumansAnimalsCells
  110. Cho EJ, Takagi T, Moore CR, Buratowski S. mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain. Genes Dev. 1997 Dec 15; 11(24):3319-26. PMID: 9407025.
    Citations: 189     Fields:    Translation:Cells
  111. Buratowski S. Multiple TATA-binding factors come back into style. Cell. 1997 Oct 03; 91(1):13-5. PMID: 9335330.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  112. Kuldell NH, Buratowski S. Genetic analysis of the large subunit of yeast transcription factor IIE reveals two regions with distinct functions. Mol Cell Biol. 1997 Sep; 17(9):5288-98. PMID: 9271406.
    Citations: 21     Fields:    Translation:AnimalsCells
  113. Takagi T, Moore CR, Diehn F, Buratowski S. An RNA 5'-triphosphatase related to the protein tyrosine phosphatases. Cell. 1997 Jun 13; 89(6):867-73. PMID: 9200605.
    Citations: 41     Fields:    Translation:AnimalsCells
  114. Sachs AB, Buratowski S. Common themes in translational and transcriptional regulation. Trends Biochem Sci. 1997 Jun; 22(6):189-92. PMID: 9204702.
    Citations: 8     Fields:    Translation:Cells
  115. Moqtaderi Z, Yale JD, Struhl K, Buratowski S. Yeast homologues of higher eukaryotic TFIID subunits. Proc Natl Acad Sci U S A. 1996 Dec 10; 93(25):14654-8. PMID: 8962109.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  116. Fresco LD, Buratowski S. Conditional mutants of the yeast mRNA capping enzyme show that the cap enhances, but is not required for, mRNA splicing. RNA. 1996 Jun; 2(6):584-96. PMID: 8718687.
    Citations: 32     Fields:    Translation:AnimalsCells
  117. Buratowski S. Mechanisms of gene activation. Science. 1995 Dec 15; 270(5243):1773-4. PMID: 8525364.
    Citations: 4     Fields:    Translation:Cells
  118. Wang Z, Buratowski S, Svejstrup JQ, Feaver WJ, Wu X, Kornberg RD, Donahue TF, Friedberg EC. The yeast TFB1 and SSL1 genes, which encode subunits of transcription factor IIH, are required for nucleotide excision repair and RNA polymerase II transcription. Mol Cell Biol. 1995 Apr; 15(4):2288-93. PMID: 7891722.
    Citations: 28     Fields:    Translation:AnimalsCells
  119. Matsui P, DePaulo J, Buratowski S. An interaction between the Tfb1 and Ssl1 subunits of yeast TFIIH correlates with DNA repair activity. Nucleic Acids Res. 1995 Mar 11; 23(5):767-72. PMID: 7708491.
    Citations: 11     Fields:    Translation:AnimalsCells
  120. Fresco LD, Buratowski S. Active site of the mRNA-capping enzyme guanylyltransferase from Saccharomyces cerevisiae: similarity to the nucleotidyl attachment motif of DNA and RNA ligases. Proc Natl Acad Sci U S A. 1994 Jul 05; 91(14):6624-8. PMID: 8022828.
    Citations: 31     Fields:    Translation:AnimalsCells
  121. Buratowski S. The basics of basal transcription by RNA polymerase II. Cell. 1994 Apr 08; 77(1):1-3. PMID: 8156586.
    Citations: 112     Fields:    Translation:AnimalsCells
  122. Buratowski S. RNA polymerase III transcription in the yeast Saccharomyces cerevisiae. Genet Eng (N Y). 1994; 16:1-9. PMID: 7765192.
    Citations: 1     Fields:    Translation:AnimalsCells
  123. Feaver WJ, Svejstrup JQ, Bardwell L, Bardwell AJ, Buratowski S, Gulyas KD, Donahue TF, Friedberg EC, Kornberg RD. Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair. Cell. 1993 Dec 31; 75(7):1379-87. PMID: 8269516.
    Citations: 100     Fields:    Translation:AnimalsCells
  124. Buratowski S, Zhou H. Functional domains of transcription factor TFIIB. Proc Natl Acad Sci U S A. 1993 Jun 15; 90(12):5633-7. PMID: 8516312.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  125. Buratowski S. DNA repair and transcription: the helicase connection. Science. 1993 Apr 02; 260(5104):37-8. PMID: 8465198.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  126. Buratowski S, Zhou H. A suppressor of TBP mutations encodes an RNA polymerase III transcription factor with homology to TFIIB. Cell. 1992 Oct 16; 71(2):221-30. PMID: 1423590.
    Citations: 66     Fields:    Translation:HumansAnimalsCells
  127. Koleske AJ, Buratowski S, Nonet M, Young RA. A novel transcription factor reveals a functional link between the RNA polymerase II CTD and TFIID. Cell. 1992 May 29; 69(5):883-94. PMID: 1591782.
    Citations: 60     Fields:    Translation:AnimalsCells
  128. Buratowski S, Zhou H. Transcription factor IID mutants defective for interaction with transcription factor IIA. Science. 1992 Feb 28; 255(5048):1130-2. PMID: 1546314.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  129. Buratowski S, Sopta M, Greenblatt J, Sharp PA. RNA polymerase II-associated proteins are required for a DNA conformation change in the transcription initiation complex. Proc Natl Acad Sci U S A. 1991 Sep 01; 88(17):7509-13. PMID: 1881889.
    Citations: 27     Fields:    Translation:HumansCells
  130. Buratowski S, Sharp PA. Transcription initiation complexes and upstream activation with RNA polymerase II lacking the C-terminal domain of the largest subunit. Mol Cell Biol. 1990 Oct; 10(10):5562-4. PMID: 2398901.
    Citations: 23     Fields:    Translation:Cells
  131. Hahn S, Buratowski S, Sharp PA, Guarente L. Identification of a yeast protein homologous in function to the mammalian general transcription factor, TFIIA. EMBO J. 1989 Nov; 8(11):3379-82. PMID: 2684641.
    Citations: 24     Fields:    Translation:AnimalsCells
  132. Hahn S, Buratowski S, Sharp PA, Guarente L. Isolation of the gene encoding the yeast TATA binding protein TFIID: a gene identical to the SPT15 suppressor of Ty element insertions. Cell. 1989 Sep 22; 58(6):1173-81. PMID: 2550146.
    Citations: 94     Fields:    Translation:Cells
  133. Hahn S, Buratowski S, Sharp PA, Guarente L. Yeast TATA-binding protein TFIID binds to TATA elements with both consensus and nonconsensus DNA sequences. Proc Natl Acad Sci U S A. 1989 Aug; 86(15):5718-22. PMID: 2569738.
    Citations: 111     Fields:    Translation:AnimalsCells
  134. Buratowski S, Hahn S, Guarente L, Sharp PA. Five intermediate complexes in transcription initiation by RNA polymerase II. Cell. 1989 Feb 24; 56(4):549-61. PMID: 2917366.
    Citations: 375     Fields:    Translation:AnimalsCells
  135. Chodosh LA, Buratowski S, Sharp PA. A yeast protein possesses the DNA-binding properties of the adenovirus major late transcription factor. Mol Cell Biol. 1989 Feb; 9(2):820-2. PMID: 2651905.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  136. Buratowski S, Hahn S, Sharp PA, Guarente L. Function of a yeast TATA element-binding protein in a mammalian transcription system. Nature. 1988 Jul 07; 334(6177):37-42. PMID: 3290687.
    Citations: 125     Fields:    Translation:HumansAnimalsCells
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