Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Christine Edry Seidman, M.D.

Co-Author

This page shows the publications co-authored by Christine Seidman and Hiroko Wakimoto.
Connection Strength

3.141
  1. LAMP2 Cardiomyopathy: Consequences of Impaired Autophagy in the Heart. J Am Heart Assoc. 2021 09 07; 10(17):e018829.
    View in: PubMed
    Score: 0.239
  2. Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy. Circulation. 2020 03 10; 141(10):828-842.
    View in: PubMed
    Score: 0.214
  3. Genetic Variants Associated With Cancer Therapy-Induced Cardiomyopathy. Circulation. 2019 07 02; 140(1):31-41.
    View in: PubMed
    Score: 0.203
  4. Hypertrophic cardiomyopathy mutations in MYBPC3 dysregulate myosin. Sci Transl Med. 2019 01 23; 11(476).
    View in: PubMed
    Score: 0.200
  5. Cardiovascular homeostasis dependence on MICU2, a regulatory subunit of the mitochondrial calcium uniporter. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):E9096-E9104.
    View in: PubMed
    Score: 0.182
  6. Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. Cell Rep. 2017 06 13; 19(11):2410.
    View in: PubMed
    Score: 0.178
  7. Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis. Cell Rep. 2016 12 20; 17(12):3292-3304.
    View in: PubMed
    Score: 0.173
  8. Single-Cell Resolution of Temporal Gene Expression during Heart Development. Dev Cell. 2016 11 21; 39(4):480-490.
    View in: PubMed
    Score: 0.171
  9. Molecular profiling of dilated cardiomyopathy that progresses to heart failure. JCI Insight. 2016 May 05; 1(6).
    View in: PubMed
    Score: 0.165
  10. A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice. Science. 2016 Feb 05; 351(6273):617-21.
    View in: PubMed
    Score: 0.162
  11. Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis. Proc Natl Acad Sci U S A. 2015 Jul 21; 112(29):9046-51.
    View in: PubMed
    Score: 0.156
  12. Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy. Science. 2013 Oct 04; 342(6154):111-4.
    View in: PubMed
    Score: 0.138
  13. Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):18097-102.
    View in: PubMed
    Score: 0.112
  14. Cardiomyocyte Proliferative Capacity Is Restricted in Mice With Lmna Mutation. Front Cardiovasc Med. 2021; 8:639148.
    View in: PubMed
    Score: 0.059
  15. Isolation of Nuclei from Mammalian Cells and Tissues for Single-Nucleus Molecular Profiling. Curr Protoc. 2021 May; 1(5):e132.
    View in: PubMed
    Score: 0.058
  16. Cells of the adult human heart. Nature. 2020 12; 588(7838):466-472.
    View in: PubMed
    Score: 0.056
  17. BET bromodomain proteins regulate transcriptional reprogramming in genetic dilated cardiomyopathy. JCI Insight. 2020 08 06; 5(15).
    View in: PubMed
    Score: 0.055
  18. Yin Yang 1 Suppresses Dilated Cardiomyopathy and Cardiac Fibrosis Through Regulation of Bmp7 and Ctgf. Circ Res. 2019 10 11; 125(9):834-846.
    View in: PubMed
    Score: 0.052
  19. IL-11 is a crucial determinant of cardiovascular fibrosis. Nature. 2017 12 07; 552(7683):110-115.
    View in: PubMed
    Score: 0.046
  20. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 2017 04 20; 169(3):510-522.e20.
    View in: PubMed
    Score: 0.044
  21. Loss of RNA expression and allele-specific expression associated with congenital heart disease. Nat Commun. 2016 09 27; 7:12824.
    View in: PubMed
    Score: 0.042
  22. De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies. Science. 2015 Dec 04; 350(6265):1262-6.
    View in: PubMed
    Score: 0.040
  23. Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis. J Clin Invest. 2015 Nov 02; 125(11):4122-34.
    View in: PubMed
    Score: 0.040
  24. 5'RNA-Seq identifies Fhl1 as a genetic modifier in cardiomyopathy. J Clin Invest. 2014 Mar; 124(3):1364-70.
    View in: PubMed
    Score: 0.035
  25. De novo mutations in histone-modifying genes in congenital heart disease. Nature. 2013 Jun 13; 498(7453):220-3.
    View in: PubMed
    Score: 0.034
  26. Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14035-40.
    View in: PubMed
    Score: 0.032
  27. Activation of multiple signaling pathways causes developmental defects in mice with a Noonan syndrome–associated Sos1 mutation. J Clin Invest. 2010 Dec; 120(12):4353-65.
    View in: PubMed
    Score: 0.028
  28. Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-ß. J Clin Invest. 2010 Oct; 120(10):3520-9.
    View in: PubMed
    Score: 0.028
  29. Prevention of ventricular arrhythmia and calcium dysregulation in a catecholaminergic polymorphic ventricular tachycardia mouse model carrying calsequestrin-2 mutation. J Cardiovasc Electrophysiol. 2011 Mar; 22(3):316-24.
    View in: PubMed
    Score: 0.028
  30. Dissecting spatio-temporal protein networks driving human heart development and related disorders. Mol Syst Biol. 2010 Jun 22; 6:381.
    View in: PubMed
    Score: 0.028
  31. Dissection of chromosome 18 blood pressure and salt-sensitivity quantitative trait loci in the spontaneously hypertensive rat. Hypertension. 2009 Sep; 54(3):639-45.
    View in: PubMed
    Score: 0.026
  32. Pheochromocytoma-induced cardiomyopathy is modulated by the synergistic effects of cell-secreted factors. Circ Heart Fail. 2009 Mar; 2(2):121-8.
    View in: PubMed
    Score: 0.025
  33. Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease. J Mol Cell Cardiol. 2008 Feb; 44(2):293-303.
    View in: PubMed
    Score: 0.023
  34. Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage. J Clin Invest. 2007 May; 117(5):1432-9.
    View in: PubMed
    Score: 0.022
  35. A mouse model of congenital heart disease: cardiac arrhythmias and atrial septal defect caused by haploinsufficiency of the cardiac transcription factor Csx/Nkx2.5. Cold Spring Harb Symp Quant Biol. 2002; 67:317-25.
    View in: PubMed
    Score: 0.015
  36. Ventricular arrhythmia vulnerability in cardiomyopathic mice with homozygous mutant Myosin-binding protein C gene. Circulation. 2001 Nov 27; 104(22):2734-9.
    View in: PubMed
    Score: 0.015
  37. Comparison of two murine models of familial hypertrophic cardiomyopathy. Circ Res. 2001 Mar 02; 88(4):383-9.
    View in: PubMed
    Score: 0.014
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.