Harvard Catalyst Profiles

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Denise L. Jacobson, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Margossian R, Williams PL, Yu W, Jacobson DL, Geffner ME, DiMeglio LA, Van Dyke RB, Spector SA, Schuster GU, Stephensen CB, Miller TL, Lipshultz SE. Markers of Bone Mineral Metabolism and Cardiac Structure and Function in Perinatally HIV-Infected and HIV-Exposed but Uninfected Children and Adolescents. J Acquir Immune Defic Syndr. 2019 Jun 01; 81(2):238-246. PMID: 30865170.
    Citations:    
  2. Sudfeld CR, Jacobson DL, Rueda NM, Neri D, Mendez AJ, Butler L, Siminski S, Hendricks KM, Mellins CA, Duggan CP, Miller TL. Third trimester vitamin D status is associated with birth outcomes and linear growth of HIV-exposed uninfected infants in the United States. J Acquir Immune Defic Syndr. 2019 Apr 01. PMID: 31021992.
    Citations:    
  3. Jao J, Jacobson DL, Yu W, Borkowsky W, Geffner ME, McFarland EJ, Patel K, Williams PL, Miller T. A comparison of metabolic outcomes between obese HIV-exposed uninfected youth from the PHACS SMARTT Study and HIV-unexposed youth from the NHANES Study in the U.S. J Acquir Immune Defic Syndr. 2019 Feb 27. PMID: 30844997.
    Citations:    
  4. Moscicki AB, Karalius B, Tassiopoulos K, Yao TJ, Jacobson DL, Patel K, Purswani M, Seage GR. Human Papillomavirus Antibody Levels and Quadrivalent Vaccine Clinical Effectiveness in Perinatally Human Immunodeficiency Virus-infected and Exposed, Uninfected Youth. Clin Infect Dis. 2019 Feb 21. PMID: 30927547.
    Citations:    
  5. Zash R, Rough K, Jacobson DL, Diseko M, Mayondi G, Mmalane M, Essex M, Petlo C, Lockman S, Makhema J, Shapiro RL. Effect of Gestational Age at Tenofovir-Emtricitabine-Efavirenz Initiation on Adverse Birth Outcomes in Botswana. J Pediatric Infect Dis Soc. 2018 Aug 17; 7(3):e148-e151. PMID: 29688554.
    Citations:    Fields:    Translation:Humans
  6. Zash R, Jacobson DL, Diseko M, Mayondi G, Mmalane M, Essex M, Gaolethe T, Petlo C, Lockman S, Holmes LB, Makhema J, Shapiro RL. Comparative safety of dolutegravir-based or efavirenz-based antiretroviral treatment started during pregnancy in Botswana: an observational study. Lancet Glob Health. 2018 07; 6(7):e804-e810. PMID: 29880310.
    Citations: 1     Fields:    
  7. Geffner ME, Patel K, Jacobson DL, Wu J, Miller TL, Hazra R, Gerschenson M, Sharma T, Silio M, Jao J, Takemoto JK, Van Dyke RB, DiMeglio LA. Changes in insulin sensitivity over time and associated factors in HIV-infected adolescents. AIDS. 2018 03 13; 32(5):613-622. PMID: 29280758.
    Citations:    Fields:    
  8. Caniglia EC, Zash R, Jacobson DL, Diseko M, Mayondi G, Lockman S, Chen JY, Mmalane M, Makhema J, Hernán MA, Shapiro RL. Emulating a target trial of antiretroviral therapy regimens started before conception and risk of adverse birth outcomes. AIDS. 2018 Jan 02; 32(1):113-120. PMID: 29112066.
    Citations:    Fields:    Translation:Humans
  9. Jacobson DL, Lindsey JC, Coull BA, Mulligan K, Bhagwat P, Aldrovandi GM. The Association of Fat and Lean Tissue With Whole Body and Spine Bone Mineral Density Is Modified by HIV Status and Sex in Children and Youth. Pediatr Infect Dis J. 2018 Jan; 37(1):71-77. PMID: 28817419.
    Citations:    Fields:    Translation:Humans
  10. Zash R, Jacobson DL, Diseko M, Mayondi G, Mmalane M, Essex M, Petlo C, Lockman S, Makhema J, Shapiro RL. Comparative Safety of Antiretroviral Treatment Regimens in Pregnancy. JAMA Pediatr. 2017 10 02; 171(10):e172222. PMID: 28783807.
    Citations: 8     Fields:    Translation:Humans
  11. Jacobson DL, Stephensen CB, Miller TL, Patel K, Chen JS, Van Dyke RB, Mirza A, Schuster GU, Hazra R, Ellis A, Brummel SS, Geffner ME, Silio M, Spector SA, DiMeglio LA. Associations of Low Vitamin D and Elevated Parathyroid Hormone Concentrations With Bone Mineral Density in Perinatally HIV-Infected Children. J Acquir Immune Defic Syndr. 2017 09 01; 76(1):33-42. PMID: 28797019.
    Citations: 1     Fields:    Translation:Humans
  12. Bellavia A, Williams PL, DiMeglio LA, Hazra R, Abzug MJ, Patel K, Jacobson DL, Van Dyke RB, Geffner ME. Delay in sexual maturation in perinatally HIV-infected youths is mediated by poor growth. AIDS. 2017 06 01; 31(9):1333-1341. PMID: 28358737.
    Citations: 1     Fields:    Translation:Humans
  13. Shearer WT, Jacobson DL, Yu W, Siberry GK, Purswani M, Siminski S, Butler L, Leister E, Scott G, Van Dyke RB, Yogev R, Paul ME, Puga A, Colin AA, Kattan M. Long-term pulmonary complications in perinatally HIV-infected youth. J Allergy Clin Immunol. 2017 Oct; 140(4):1101-1111.e7. PMID: 28279683.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  14. Jacobson DL, Patel K, Williams PL, Geffner ME, Siberry GK, DiMeglio LA, Crain MJ, Mirza A, Chen JS, McFarland E, Kacanek D, Silio M, Rich K, Borkowsky W, Van Dyke RB, Miller TL. Growth at 2 Years of Age in HIV-exposed Uninfected Children in the United States by Trimester of Maternal Antiretroviral Initiation. Pediatr Infect Dis J. 2017 02; 36(2):189-197. PMID: 27798548.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  15. Takemoto JK, Miller TL, Wang J, Jacobson DL, Geffner ME, Van Dyke RB, Gerschenson M. Insulin resistance in HIV-infected youth is associated with decreased mitochondrial respiration. AIDS. 2017 01 02; 31(1):15-23. PMID: 27755108.
    Citations: 6     Fields:    Translation:HumansCells
  16. Miller TL, Jacobson DL, Somarriba G, Neri D, Kurtz-Vraney J, Graham P, Gillman MW, Landy DC, Siminski S, Butler L, Rich KC, Hendricks K, Ludwig DA. A multicenter study of diet quality on birth weight and gestational age in infants of HIV-infected women. Matern Child Nutr. 2017 10; 13(4). PMID: 27863014.
    Citations:    Fields:    Translation:Humans
  17. Caniglia EC, Patel K, Huo Y, Williams PL, Kapetanovic S, Rich KC, Sirois PA, Jacobson DL, Hernandez-Diaz S, Hernán MA, Seage GR. Atazanavir exposure in utero and neurodevelopment in infants: a comparative safety study. AIDS. 2016 05 15; 30(8):1267-78. PMID: 26867136.
    Citations: 5     Fields:    Translation:Humans
  18. Siberry GK, Jacobson DL. Reply to Koo et al. Clin Infect Dis. 2016 05 15; 62(10):1324-5. PMID: 26936672.
    Citations:    Fields:    
  19. Himes SK, Wu JW, Jacobson DL, Tassiopoulos K, Hazra R, Kacanek D, Van Dyke RB, Rich KC, Siberry GK, Huestis MA. Meconium Tenofovir Concentrations and Growth and Bone Outcomes in Prenatally Tenofovir Exposed HIV-Uninfected Children. Pediatr Infect Dis J. 2015 Aug; 34(8):851-7. PMID: 25961889.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  20. Siberry GK, Jacobson DL, Kalkwarf HJ, Wu JW, DiMeglio LA, Yogev R, Knapp KM, Wheeler JJ, Butler L, Hazra R, Miller TL, Seage GR, Van Dyke RB, Barr E, Davtyan M, Mofenson LM, Rich KC. Lower Newborn Bone Mineral Content Associated With Maternal Use of Tenofovir Disoproxil Fumarate During Pregnancy. Clin Infect Dis. 2015 Sep 15; 61(6):996-1003. PMID: 26060285.
    Citations: 29     Fields:    Translation:HumansPHPublic Health
  21. Krishnan S, Schouten JT, Atkinson B, Brown TT, Wohl DA, McComsey GA, Glesby MJ, Shikuma C, Haubrich R, Jacobson DL. Changes in metabolic syndrome status after initiation of antiretroviral therapy. J Acquir Immune Defic Syndr. 2015 Jan 01; 68(1):73-80. PMID: 25321179.
    Citations: 5     Fields:    Translation:Humans
  22. Patel K, Wang J, Jacobson DL, Lipshultz SE, Landy DC, Geffner ME, Dimeglio LA, Seage GR, Williams PL, Van Dyke RB, Siberry GK, Shearer WT, Young L, Scott GB, Wilkinson JD, Fisher SD, Starc TJ, Miller TL. Aggregate risk of cardiovascular disease among adolescents perinatally infected with the human immunodeficiency virus. Circulation. 2014 Mar 18; 129(11):1204-12. PMID: 24366631.
    Citations: 14     Fields:    Translation:Humans
  23. Sharma TS, Jacobson DL, Anderson L, Gerschenson M, Van Dyke RB, McFarland EJ, Miller TL. Short communication: The relationship between mitochondrial dysfunction and insulin resistance in HIV-infected children receiving antiretroviral therapy. AIDS Res Hum Retroviruses. 2013 Sep; 29(9):1211-7. PMID: 23742635.
    Citations: 5     Fields:    Translation:HumansCells
  24. Williams PL, Abzug MJ, Jacobson DL, Wang J, Van Dyke RB, Hazra R, Patel K, Dimeglio LA, McFarland EJ, Silio M, Borkowsky W, Seage GR, Oleske JM, Geffner ME. Pubertal onset in children with perinatal HIV infection in the era of combination antiretroviral treatment. AIDS. 2013 Jul 31; 27(12):1959-70. PMID: 24145244.
    Citations: 15     Fields:    Translation:HumansCells
  25. Lipshultz SE, Williams PL, Wilkinson JD, Leister EC, Van Dyke RB, Shearer WT, Rich KC, Hazra R, Kaltman JR, Jacobson DL, Dooley LB, Scott GB, Rabideau N, Colan SD. Cardiac status of children infected with human immunodeficiency virus who are receiving long-term combination antiretroviral therapy: results from the Adolescent Master Protocol of the Multicenter Pediatric HIV/AIDS Cohort Study. JAMA Pediatr. 2013 Jun; 167(6):520-7. PMID: 23608879.
    Citations: 18     Fields:    Translation:HumansCTClinical Trials
  26. Jacobson DL, Bousvaros A, Ashworth L, Carey R, Shrier LA, Burchett SK, Renna H, Lu Y. Immunogenicity and tolerability to human papillomavirus-like particle vaccine in girls and young women with inflammatory bowel disease. Inflamm Bowel Dis. 2013 Jun; 19(7):1441-9. PMID: 23567780.
    Citations: 11     Fields:    Translation:HumansCells
  27. DiMeglio LA, Wang J, Siberry GK, Miller TL, Geffner ME, Hazra R, Borkowsky W, Chen JS, Dooley L, Patel K, van Dyke RB, Fielding RA, Gurmu Y, Jacobson DL. Bone mineral density in children and adolescents with perinatal HIV infection. AIDS. 2013 Jan 14; 27(2):211-20. PMID: 23032412.
    Citations: 22     Fields:    Translation:Humans
  28. Krishnan S, Schouten JT, Atkinson B, Brown T, Wohl D, McComsey GA, Glesby MJ, Shikuma C, Haubrich R, Tebas P, Campbell TB, Jacobson DL. Metabolic syndrome before and after initiation of antiretroviral therapy in treatment-naive HIV-infected individuals. J Acquir Immune Defic Syndr. 2012 Nov 01; 61(3):381-9. PMID: 22828718.
    Citations: 22     Fields:    Translation:Humans
  29. Siberry GK, Williams PL, Mendez H, Seage GR, Jacobson DL, Hazra R, Rich KC, Griner R, Tassiopoulos K, Kacanek D, Mofenson LM, Miller T, DiMeglio LA, Watts DH. Safety of tenofovir use during pregnancy: early growth outcomes in HIV-exposed uninfected infants. AIDS. 2012 Jun 01; 26(9):1151-9. PMID: 22382151.
    Citations: 41     Fields:    Translation:Humans
  30. Williams PL, Seage GR, Van Dyke RB, Siberry GK, Griner R, Tassiopoulos K, Yildirim C, Read JS, Huo Y, Hazra R, Jacobson DL, Mofenson LM, Rich K. A trigger-based design for evaluating the safety of in utero antiretroviral exposure in uninfected children of human immunodeficiency virus-infected mothers. Am J Epidemiol. 2012 May 01; 175(9):950-61. PMID: 22491086.
    Citations: 21     Fields:    Translation:HumansPHPublic Health
  31. Lindsey JC, Jacobson DL, Li H, Houseman EA, Aldrovandi GM, Mulligan K. Using cluster heat maps to investigate relationships between body composition and laboratory measurements in HIV-infected and HIV-uninfected children and young adults. J Acquir Immune Defic Syndr. 2012 Mar 01; 59(3):325-8. PMID: 22083069.
    Citations: 2     Fields:    Translation:HumansCells
  32. Jacobson DL, Patel K, Siberry GK, Van Dyke RB, DiMeglio LA, Geffner ME, Chen JS, McFarland EJ, Borkowsky W, Silio M, Fielding RA, Siminski S, Miller TL. Body fat distribution in perinatally HIV-infected and HIV-exposed but uninfected children in the era of highly active antiretroviral therapy: outcomes from the Pediatric HIV/AIDS Cohort Study. Am J Clin Nutr. 2011 Dec; 94(6):1485-95. PMID: 22049166.
    Citations: 18     Fields:    Translation:Humans
  33. Siberry GK, Leister E, Jacobson DL, Foster SB, Seage GR, Lipshultz SE, Paul ME, Purswani M, Colin AA, Scott G, Shearer WT. Increased risk of asthma and atopic dermatitis in perinatally HIV-infected children and adolescents. Clin Immunol. 2012 Feb; 142(2):201-8. PMID: 22094294.
    Citations: 14     Fields:    Translation:Humans
  34. Geffner ME, Patel K, Miller TL, Hazra R, Silio M, Van Dyke RB, Borkowsky W, Worrell C, DiMeglio LA, Jacobson DL. Factors associated with insulin resistance among children and adolescents perinatally infected with HIV-1 in the pediatric HIV/AIDS cohort study. Horm Res Paediatr. 2011; 76(6):386-91. PMID: 22042056.
    Citations: 22     Fields:    Translation:HumansCells
  35. Jacobson DL, Williams P, Tassiopoulos K, Melvin A, Hazra R, Farley J. Clinical management and follow-up of hypercholesterolemia among perinatally HIV-infected children enrolled in the PACTG 219C study. J Acquir Immune Defic Syndr. 2011 Aug 15; 57(5):413-20. PMID: 21602698.
    Citations: 7     Fields:    Translation:Humans
  36. Siberry GK, Li H, Jacobson D. Fracture risk by HIV infection status in perinatally HIV-exposed children. AIDS Res Hum Retroviruses. 2012 Mar; 28(3):247-50. PMID: 22471877.
    Citations: 8     Fields:    Translation:Humans
  37. Krishnan S, Schouten JT, Jacobson DL, Benson CA, Collier AC, Koletar SL, Santana J, Sattler FR, Mitsuyasu R. Incidence of non-AIDS-defining cancer in antiretroviral treatment-naïve subjects after antiretroviral treatment initiation: an ACTG longitudinal linked randomized trials analysis. Oncology. 2011; 80(1-2):42-9. PMID: 21606663.
    Citations: 15     Fields:    Translation:HumansCells
  38. Jacobson DL, Lindsey JC, Gordon CM, Moye J, Hardin DS, Mulligan K, Aldrovandi GM. Total body and spinal bone mineral density across Tanner stage in perinatally HIV-infected and uninfected children and youth in PACTG 1045. AIDS. 2010 Mar 13; 24(5):687-96. PMID: 20168204.
    Citations: 24     Fields:    Translation:Humans
  39. Kacanek D, Jacobson DL, Spiegelman D, Wanke C, Isaac R, Wilson IB. Incident depression symptoms are associated with poorer HAART adherence: a longitudinal analysis from the Nutrition for Healthy Living study. J Acquir Immune Defic Syndr. 2010 Feb; 53(2):266-72. PMID: 20104122.
    Citations: 32     Fields:    Translation:Humans
  40. Lu Y, Jacobson D, Bousvaros A. Immunizations in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2009 Sep; 15(9):1417-23. PMID: 19408335.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  41. Aldrovandi GM, Lindsey JC, Jacobson DL, Zadzilka A, Sheeran E, Moye J, Borum P, Meyer WA, Hardin DS, Mulligan K. Morphologic and metabolic abnormalities in vertically HIV-infected children and youth. AIDS. 2009 Mar 27; 23(6):661-72. PMID: 19279441.
    Citations: 45     Fields:    Translation:HumansCells
  42. Lu Y, Jacobson DL, Ashworth LA, Grand RJ, Meyer AL, McNeal MM, Gregas MC, Burchett SK, Bousvaros A. Immune response to influenza vaccine in children with inflammatory bowel disease. Am J Gastroenterol. 2009 Feb; 104(2):444-53. PMID: 19174786.
    Citations: 33     Fields:    Translation:HumansCellsCTClinical Trials
  43. Jacobson DL, Spiegelman D, Knox TK, Wilson IB. Evolution and predictors of change in total bone mineral density over time in HIV-infected men and women in the nutrition for healthy living study. J Acquir Immune Defic Syndr. 2008 Nov 01; 49(3):298-308. PMID: 18845956.
    Citations: 26     Fields:    Translation:Humans
  44. Isaac R, Jacobson D, Wanke C, Hendricks K, Knox TA, Wilson IB. Declines in dietary macronutrient intake in persons with HIV infection who develop depression. Public Health Nutr. 2008 Feb; 11(2):124-31. PMID: 17582240.
    Citations: 6     Fields:    Translation:Humans
  45. Mangili A, Jacobson DL, Gerrior J, Polak JF, Gorbach SL, Wanke CA. Metabolic syndrome and subclinical atherosclerosis in patients infected with HIV. Clin Infect Dis. 2007 May 15; 44(10):1368-74. PMID: 17443477.
    Citations: 31     Fields:    Translation:HumansCells
  46. Jacobson DL, Tang AM, Spiegelman D, Thomas AM, Skinner S, Gorbach SL, Wanke C. Incidence of metabolic syndrome in a cohort of HIV-infected adults and prevalence relative to the US population (National Health and Nutrition Examination Survey). J Acquir Immune Defic Syndr. 2006 Dec 01; 43(4):458-66. PMID: 16980905.
    Citations: 37     Fields:    Translation:HumansCells
  47. Wilson IB, Jacobson D. Regarding: "Antidepressant treatment improves adherence to antiretroviral therapy among depressed HIV-infected patients". J Acquir Immune Defic Syndr. 2006 Feb 01; 41(2):254-5; author reply 255. PMID: 16394863.
    Citations: 2     Fields:    Translation:Humans
  48. Jones CY, Wilson IB, Greenberg AS, Shevitz A, Knox TA, Gorbach SL, Spiegelman D, Jacobson DL, Wanke C. Insulin resistance in HIV-infected men and women in the nutrition for healthy living cohort. J Acquir Immune Defic Syndr. 2005 Oct 01; 40(2):202-11. PMID: 16186739.
    Citations: 9     Fields:    Translation:Humans
  49. Tang AM, Jacobson DL, Spiegelman D, Knox TA, Wanke C. Increasing risk of 5% or greater unintentional weight loss in a cohort of HIV-infected patients, 1995 to 2003. J Acquir Immune Defic Syndr. 2005 Sep 01; 40(1):70-6. PMID: 16123685.
    Citations: 19     Fields:    Translation:Humans
  50. Jacobson DL, Spiegelman D, Duggan C, Weinberg GA, Bechard L, Furuta L, Nicchitta J, Gorbach SL, Miller TL. Predictors of bone mineral density in human immunodeficiency virus-1 infected children. J Pediatr Gastroenterol Nutr. 2005 Sep; 41(3):339-46. PMID: 16131991.
    Citations: 20     Fields:    Translation:HumansCells
  51. Jacobson DL, Knox T, Spiegelman D, Skinner S, Gorbach S, Wanke C. Prevalence of, evolution of, and risk factors for fat atrophy and fat deposition in a cohort of HIV-infected men and women. Clin Infect Dis. 2005 Jun 15; 40(12):1837-45. PMID: 15909274.
    Citations: 35     Fields:    Translation:Humans
  52. Mwamburi DM, Wilson IB, Jacobson DL, Spiegelman D, Gorbach SL, Knox TA, Wanke CA. Understanding the role of HIV load in determining weight change in the era of highly active antiretroviral therapy. Clin Infect Dis. 2005 Jan 01; 40(1):167-73. PMID: 15614708.
    Citations: 9     Fields:    Translation:HumansCells
  53. Jacobson DL, Bica I, Knox TA, Wanke C, Tchetgen E, Spiegelman D, Silva M, Gorbach S, Wilson IB. Difficulty swallowing and lack of receipt of highly active antiretroviral therapy predict acute weight loss in human immunodeficiency virus disease. Clin Infect Dis. 2003 Nov 15; 37(10):1349-56. PMID: 14583869.
    Citations: 2     Fields:    Translation:Humans
  54. Jacobson DL, Wu AW, Feinberg J. Health-related quality of life predicts survival, cytomegalovirus disease, and study retention in clinical trial participants with advanced HIV disease. J Clin Epidemiol. 2003 Sep; 56(9):874-9. PMID: 14505773.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  55. Gill CJ, Griffith JL, Jacobson D, Skinner S, Gorbach SL, Wilson IB. Relationship of HIV viral loads, CD4 counts, and HAART use to health-related quality of life. J Acquir Immune Defic Syndr. 2002 Aug 15; 30(5):485-92. PMID: 12154339.
    Citations: 38     Fields:    Translation:HumansCells
  56. Mandelblatt JS, Lawrence WF, Womack SM, Jacobson D, Yi B, Hwang YT, Gold K, Barter J, Shah K. Benefits and costs of using HPV testing to screen for cervical cancer. JAMA. 2002 May 08; 287(18):2372-81. PMID: 11988058.
    Citations: 45     Fields:    Translation:HumansCellsPHPublic Health
  57. Baigis J, Korniewicz DM, Chase G, Butz A, Jacobson D, Wu AW. Effectiveness of a home-based exercise intervention for HIV-infected adults: a randomized trial. J Assoc Nurses AIDS Care. 2002 Mar-Apr; 13(2):33-45. PMID: 11936063.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.