Harvard Catalyst Profiles

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Mei X. Wu, Ph.D., Ph.D., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI153528 (WU, MEI X) May 24, 2021 - Apr 30, 2026
    NIH
    A new mucosal adjuvant for augmenting influenza vaccines in elderly
    Role: Principal Investigator
  2. R01AI146588 (WU, MEI X) Aug 7, 2020 - Jul 31, 2024
    NIH
    Biomimetic nanoparticles to enhance the breadth of influenza vaccines
    Role: Principal Investigator
  3. R21AI149012 (WU, MEI X) Feb 1, 2020 - Jan 31, 2022
    NIH
    Delivery of Powdered Vaccines for Improving Newborn Vaccination
    Role: Principal Investigator
  4. R56AI141717 (WU, MEI X) Aug 6, 2019 - Jul 31, 2021
    NIH
    Biomimetic nanoparticles for augmenting influenza vaccines in elderly
    Role: Principal Investigator
  5. R21HL141016 (WU, MEI X) Apr 15, 2018 - Mar 31, 2021
    NIH
    Potentials of a Newly Engineered Device for Treatment of Neonatal Thrombocytopenia
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX. Stress-induced hematopoietic failure in the absence of immediate early response gene X-1 (IEX-1, IER3). Haematologica. 2014 Feb; 99(2):282-91. PMID: 24056813.
    Citations: 11     Fields:    Translation:AnimalsCells
  2. Wu MX, Ustyugova IV, Han L, Akilov OE. Immediate early response gene X-1, a potential prognostic biomarker in cancers. Expert Opin Ther Targets. 2013 May; 17(5):593-606. PMID: 23379921.
    Citations: 10     Fields:    Translation:HumansAnimals
  3. Yu B, Shahid M, Egorina EM, Sovershaev MA, Raher MJ, Lei C, Wu MX, Bloch KD, Zapol WM. Endothelial dysfunction enhances vasoconstriction due to scavenging of nitric oxide by a hemoglobin-based oxygen carrier. Anesthesiology. 2010 Mar; 112(3):586-94. PMID: 20179495.
    Citations: 25     Fields:    Translation:Animals
  4. Akilov OE, Ustyugova IV, Zhi L, Hasan T, Wu MX. Enhanced susceptibility to Leishmania infection in resistant mice in the absence of immediate early response gene X-1. J Immunol. 2009 Dec 15; 183(12):7994-8003. PMID: 19923449.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  5. Jin YZ, Thompson BD, Zhou ZY, Fu Y, Birnbaumer L, Wu MX. Reciprocal function of Galphai2 and Galphai3 in graft-versus-host disease. Eur J Immunol. 2008 Jul; 38(7):1988-98. PMID: 18521956.
    Citations: 3     Fields:    Translation:AnimalsCells
  6. Jin Y, Wu MX. Requirement of Galphai in thymic homing and early T cell development. Mol Immunol. 2008 Jul; 45(12):3401-10. PMID: 18501427.
    Citations: 6     Fields:    Translation:AnimalsCells
  7. Sabatakos G, Rowe GC, Kveiborg M, Wu M, Neff L, Chiusaroli R, Philbrick WM, Baron R. Doubly truncated FosB isoform (Delta2DeltaFosB) induces osteosclerosis in transgenic mice and modulates expression and phosphorylation of Smads in osteoblasts independent of intrinsic AP-1 activity. J Bone Miner Res. 2008 May; 23(5):584-95. PMID: 18433296.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  8. Castano AP, Mroz P, Wu MX, Hamblin MR. Photodynamic therapy plus low-dose cyclophosphamide generates antitumor immunity in a mouse model. Proc Natl Acad Sci U S A. 2008 Apr 08; 105(14):5495-500. PMID: 18378905.
    Citations: 60     Fields:    Translation:AnimalsCells
  9. Thompson BD, Jin Y, Wu KH, Colvin RA, Luster AD, Birnbaumer L, Wu MX. Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling. J Biol Chem. 2007 Mar 30; 282(13):9547-9555. PMID: 17289675.
    Citations: 25     Fields:    Translation:AnimalsCells
  10. Shen L, Guo J, Santos-Berrios C, Wu MX. Distinct domains for anti- and pro-apoptotic activities of IEX-1. J Biol Chem. 2006 Jun 02; 281(22):15304-11. PMID: 16567805.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  11. Wu JY, Jin Y, Edwards RA, Zhang Y, Finegold MJ, Wu MX. Impaired TGF-beta responses in peripheral T cells of G alpha i2-/- mice. J Immunol. 2005 May 15; 174(10):6122-8. PMID: 15879107.
    Citations: 9     Fields:    Translation:AnimalsCells
  12. Kveiborg M, Sabatakos G, Chiusaroli R, Wu M, Philbrick WM, Horne WC, Baron R. DeltaFosB induces osteosclerosis and decreases adipogenesis by two independent cell-autonomous mechanisms. Mol Cell Biol. 2004 Apr; 24(7):2820-30. PMID: 15024071.
    Citations: 33     Fields:    Translation:AnimalsCells
  13. Greenspan SL, Emkey RD, Bone HG, Weiss SR, Bell NH, Downs RW, McKeever C, Miller SS, Davidson M, Bolognese MA, Mulloy AL, Heyden N, Wu M, Kaur A, Lombardi A. Significant differential effects of alendronate, estrogen, or combination therapy on the rate of bone loss after discontinuation of treatment of postmenopausal osteoporosis. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2002 Dec 03; 137(11):875-83. PMID: 12458987.
    Citations: 46     Fields:    Translation:HumansCTClinical Trials
  14. Xue L, Chu F, Cheng Y, Sun X, Borthakur A, Ramarao M, Pandey P, Wu M, Schlossman SF, Prasad KV. Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosis. Proc Natl Acad Sci U S A. 2002 May 14; 99(10):6925-30. PMID: 12011449.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  15. Zhang Y, Schlossman SF, Edwards RA, Ou CN, Gu J, Wu MX. Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice. Proc Natl Acad Sci U S A. 2002 Jan 22; 99(2):878-83. PMID: 11782530.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.