Harvard Catalyst Profiles

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Alkes Price, Ph.D.

Co-Author

This page shows the publications co-authored by Alkes Price and Steven Gazal.
Connection Strength

7.257
  1. Author Correction: Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection. Nat Genet. 2019 Aug; 51(8):1295.
    View in: PubMed
    Score: 0.873
  2. Reconciling S-LDSC and LDAK functional enrichment estimates. Nat Genet. 2019 08; 51(8):1202-1204.
    View in: PubMed
    Score: 0.873
  3. Functional architecture of low-frequency variants highlights strength of negative selection across coding and non-coding annotations. Nat Genet. 2018 11; 50(11):1600-1607.
    View in: PubMed
    Score: 0.825
  4. Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection. Nat Genet. 2017 Oct; 49(10):1421-1427.
    View in: PubMed
    Score: 0.766
  5. Population-specific causal disease effect sizes in functionally important regions impacted by selection. Nat Commun. 2021 02 17; 12(1):1098.
    View in: PubMed
    Score: 0.243
  6. Improving the informativeness of Mendelian disease-derived pathogenicity scores for common disease. Nat Commun. 2020 12 07; 11(1):6258.
    View in: PubMed
    Score: 0.240
  7. Functionally informed fine-mapping and polygenic localization of complex trait heritability. Nat Genet. 2020 12; 52(12):1355-1363.
    View in: PubMed
    Score: 0.239
  8. Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability. Hum Mol Genet. 2020 05 08; 29(7):1057-1067.
    View in: PubMed
    Score: 0.230
  9. Liability threshold modeling of case-control status and family history of disease increases association power. Nat Genet. 2020 05; 52(5):541-547.
    View in: PubMed
    Score: 0.229
  10. Genes with High Network Connectivity Are Enriched for Disease Heritability. Am J Hum Genet. 2019 Dec 05; 105(6):1302.
    View in: PubMed
    Score: 0.223
  11. Functional disease architectures reveal unique biological role of transposable elements. Nat Commun. 2019 09 06; 10(1):4054.
    View in: PubMed
    Score: 0.220
  12. Extreme Polygenicity of Complex Traits Is Explained by Negative Selection. Am J Hum Genet. 2019 09 05; 105(3):456-476.
    View in: PubMed
    Score: 0.218
  13. Genes with High Network Connectivity Are Enriched for Disease Heritability. Am J Hum Genet. 2019 05 02; 104(5):896-913.
    View in: PubMed
    Score: 0.214
  14. Disease Heritability Enrichment of Regulatory Elements Is Concentrated in Elements with Ancient Sequence Age and Conserved Function across Species. Am J Hum Genet. 2019 04 04; 104(4):611-624.
    View in: PubMed
    Score: 0.213
  15. Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection. Nat Commun. 2019 02 15; 10(1):790.
    View in: PubMed
    Score: 0.211
  16. Leveraging Polygenic Functional Enrichment to Improve GWAS Power. Am J Hum Genet. 2019 01 03; 104(1):65-75.
    View in: PubMed
    Score: 0.209
  17. Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk. Nat Genet. 2018 10; 50(10):1483-1493.
    View in: PubMed
    Score: 0.205
  18. Mixed-model association for biobank-scale datasets. Nat Genet. 2018 07; 50(7):906-908.
    View in: PubMed
    Score: 0.202
  19. Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits. Nat Genet. 2018 07; 50(7):1041-1047.
    View in: PubMed
    Score: 0.202
  20. Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. Nat Genet. 2018 04; 50(4):621-629.
    View in: PubMed
    Score: 0.199
  21. Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues. Am J Hum Genet. 2017 Apr 06; 100(4):605-616.
    View in: PubMed
    Score: 0.185
  22. Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations. Hum Mol Genet. 2021 May 13.
    View in: PubMed
    Score: 0.062
  23. COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets. Nature. 2021 07; 595(7865):107-113.
    View in: PubMed
    Score: 0.062
  24. A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2. bioRxiv. 2021 Feb 25.
    View in: PubMed
    Score: 0.061
  25. IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors. Am J Hum Genet. 2019 05 02; 104(5):879-895.
    View in: PubMed
    Score: 0.053
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.