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Richard Leon Sidman, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01NS036041 (SIDMAN, RICHARD L) Jul 1, 1997 - Apr 30, 2000
    NIH/NINDS
    HIGH RES BRAIN ATLAS--DATA ACQUISITION AND USER ACCESS
    Role: Principal Investigator
  2. R01EY006859 (SIDMAN, RICHARD L) Jun 1, 1990 - Nov 30, 1996
    NIH/NEI
    INBREEDING AND DISSEMINATION OF RETINAL MUTANTS
    Role: Principal Investigator
  3. U01EY006859 (SIDMAN, RICHARD L) Sep 30, 1986 - May 31, 1993
    NIH/NEI
    INHERITED RETINAL DEGENERATIONS IN MUTANTS
    Role: Principal Investigator
  4. R01EY006631 (SIDMAN, RICHARD L) Jul 1, 1986 - Mar 31, 1996
    NIH/NEI
    NEW INHERITED PROGRESSIVE RETINAL DEGENERATIONS
    Role: Principal Investigator
  5. R55EY006631 (SIDMAN, RICHARD L) Jul 1, 1986 - Mar 31, 1992
    NIH/NEI
    NEW INHERITED PROGRESSIVE RETINAL DEGENERATIONS IN MICE
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Staquicini FI, Smith TL, Tang FHF, Gelovani JG, Giordano RJ, Libutti SK, Sidman RL, Cavenee WK, Arap W, Pasqualini R. Targeted AAVP-based therapy in a mouse model of human glioblastoma: a comparison of cytotoxic versus suicide gene delivery strategies. Cancer Gene Ther. 2019 May 27. PMID: 31130731.
    Citations:    
  2. Tang FHF, Staquicini FI, Teixeira AAR, Michaloski JS, Namiyama GM, Taniwaki NN, Setubal JC, da Silva AM, Sidman RL, Pasqualini R, Arap W, Giordano RJ. A ligand motif enables differential vascular targeting of endothelial junctions between brain and retina. Proc Natl Acad Sci U S A. 2019 02 05; 116(6):2300-2305. PMID: 30670660.
    Citations:    Fields:    
  3. Chohan MO, Marchiò S, Morrison LA, Sidman RL, Cavenee WK, Dejana E, Yonas H, Pasqualini R, Arap W. Emerging Pharmacologic Targets in Cerebral Cavernous Malformation and Potential Strategies to Alter the Natural History of a Difficult Disease: A Review. JAMA Neurol. 2018 Nov 26. PMID: 30476961.
    Citations:    Fields:    
  4. D'Angelo S, Staquicini FI, Ferrara F, Staquicini DI, Sharma G, Tarleton CA, Nguyen H, Naranjo LA, Sidman RL, Arap W, Bradbury AR, Pasqualini R. Selection of phage-displayed accessible recombinant targeted antibodies (SPARTA): methodology and applications. JCI Insight. 2018 05 03; 3(9). PMID: 29720567.
    Citations:    Fields:    
  5. Brammer DW, Gillespie PJ, Tian M, Young D, Raveendran M, Williams LE, Gagea M, Benavides FJ, Perez CJ, Broaddus RR, Bernacky BJ, Barnhart KF, Alauddin MM, Bhutani MS, Gibbs RA, Sidman RL, Pasqualini R, Arap W, Rogers J, Abee CR, Gelovani JG. MLH1-rheMac hereditary nonpolyposis colorectal cancer syndrome in rhesus macaques. Proc Natl Acad Sci U S A. 2018 03 13; 115(11):2806-2811. PMID: 29490919.
    Citations: 1     Fields:    Translation:Animals
  6. Pernia CD, Nathan NH, Tobe BTD, Winquist AM, Sidman RL, Goshima Y, Snyder EY. Modeling Complex Neurological Diseases with Stem Cells: A Study of Bipolar Disorder. Results Probl Cell Differ. 2018; 66:265-282. PMID: 30209664.
    Citations:    Fields:    
  7. Staquicini DI, D'Angelo S, Ferrara F, Karjalainen K, Sharma G, Smith TL, Tarleton CA, Jaalouk DE, Kuniyasu A, Baze WB, Chaffee BK, Hanley PW, Barnhart KF, Koivunen E, Marchiò S, Sidman RL, Cortes JE, Kantarjian HM, Arap W, Pasqualini R. Therapeutic targeting of membrane-associated GRP78 in leukemia and lymphoma: preclinical efficacy in vitro and formal toxicity study of BMTP-78 in rodents and primates. Pharmacogenomics J. 2018 05 22; 18(3):436-443. PMID: 29205207.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  8. Teixeira AA, Marchiò S, Dias-Neto E, Nunes DN, da Silva IT, Chackerian B, Barry M, Lauer RC, Giordano RJ, Sidman RL, Wheeler CM, Cavenee WK, Pasqualini R, Arap W. Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses. EMBO Mol Med. 2017 10; 9(10):1327-1330. PMID: 28751581.
    Citations:    Fields:    Translation:HumansAnimalsCells
  9. Lewis VO, Devarajan E, Cardó-Vila M, Thomas DG, Kleinerman ES, Marchiò S, Sidman RL, Pasqualini R, Arap W. BMTP-11 is active in preclinical models of human osteosarcoma and a candidate targeted drug for clinical translation. Proc Natl Acad Sci U S A. 2017 07 25; 114(30):8065-8070. PMID: 28698375.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  10. Staquicini DI, Rangel R, Guzman-Rojas L, Staquicini FI, Dobroff AS, Tarleton CA, Ozbun MA, Kolonin MG, Gelovani JG, Marchiò S, Sidman RL, Hajjar KA, Arap W, Pasqualini R. Intracellular targeting of annexin A2 inhibits tumor cell adhesion, migration, and in vivo grafting. Sci Rep. 2017 06 26; 7(1):4243. PMID: 28652618.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  11. Kanamaru Y, Li J, Stewart N, Sidman RL, Takahashi E. Cerebellar Pathways in Mouse Model of Purkinje Cell Degeneration Detected by High-Angular Resolution Diffusion Imaging Tractography. Cerebellum. 2017 06; 16(3):648-655. PMID: 28102462.
    Citations:    Fields:    Translation:AnimalsCells
  12. Smith TL, Souza GR, Sidman RL, Arap W, Pasqualini R. An AAVP-based solid-phase transducing matrix for transgene delivery: potential for translational applications. Cancer Gene Ther. 2017 Aug; 24(8):358-360. PMID: 28548103.
    Citations:    Fields:    Translation:HumansCells
  13. Tobe BTD, Crain AM, Winquist AM, Calabrese B, Makihara H, Zhao WN, Lalonde J, Nakamura H, Konopaske G, Sidor M, Pernia CD, Yamashita N, Wada M, Inoue Y, Nakamura F, Sheridan SD, Logan RW, Brandel M, Wu D, Hunsberger J, Dorsett L, Duerr C, Basa RCB, McCarthy MJ, Udeshi ND, Mertins P, Carr SA, Rouleau GA, Mastrangelo L, Li J, Gutierrez GJ, Brill LM, Venizelos N, Chen G, Nye JS, Manji H, Price JH, McClung CA, Akiskal HS, Alda M, Chuang DM, Coyle JT, Liu Y, Teng YD, Ohshima T, Mikoshiba K, Sidman RL, Halpain S, Haggarty SJ, Goshima Y, Snyder EY. Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis. Proc Natl Acad Sci U S A. 2017 05 30; 114(22):E4462-E4471. PMID: 28500272.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  14. Kolonin MG, Sergeeva A, Staquicini DI, Smith TL, Tarleton CA, Molldrem JJ, Sidman RL, Marchiò S, Pasqualini R, Arap W. Interaction between Tumor Cell Surface Receptor RAGE and Proteinase 3 Mediates Prostate Cancer Metastasis to Bone. Cancer Res. 2017 06 15; 77(12):3144-3150. PMID: 28428279.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  15. Sardi SP, Viel C, Clarke J, Treleaven CM, Richards AM, Park H, Olszewski MA, Dodge JC, Marshall J, Makino E, Wang B, Sidman RL, Cheng SH, Shihabuddin LS. Glucosylceramide synthase inhibition alleviates aberrations in synucleinopathy models. Proc Natl Acad Sci U S A. 2017 03 07; 114(10):2699-2704. PMID: 28223512.
    Citations: 5     Fields:    Translation:HumansAnimals
  16. Ropper AE, Thakor DK, Han I, Yu D, Zeng X, Anderson JE, Aljuboori Z, Kim SW, Wang H, Sidman RL, Zafonte RD, Teng YD. Defining recovery neurobiology of injured spinal cord by synthetic matrix-assisted hMSC implantation. Proc Natl Acad Sci U S A. 2017 01 31; 114(5):E820-E829. PMID: 28096400.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  17. Ferrara F, Staquicini DI, Driessen WHP, D'Angelo S, Dobroff AS, Barry M, Lomo LC, Staquicini FI, Cardó-Vila M, Soghomonyan S, Alauddin MM, Flores LG, Arap MA, Lauer RC, Mathew P, Efstathiou E, Aparicio AM, Troncoso P, Navone NM, Logothetis CJ, Marchiò S, Gelovani JG, Sidman RL, Pasqualini R, Arap W. Targeted molecular-genetic imaging and ligand-directed therapy in aggressive variant prostate cancer. Proc Natl Acad Sci U S A. 2016 Nov 08; 113(45):12786-12791. PMID: 27791181.
    Citations: 4     Fields:    
  18. Dobroff AS, D'Angelo S, Eckhardt BL, Ferrara F, Staquicini DI, Cardó-Vila M, Staquicini FI, Nunes DN, Kim K, Driessen WHP, Hajitou A, Lomo LC, Barry M, Krishnamurthy S, Sahin A, Woodward WA, Prossnitz ER, Anderson RL, Dias-Neto E, Brown-Glaberman UA, Royce ME, Ueno NT, Cristofanilli M, Hortobagyi GN, Marchiò S, Gelovani JG, Sidman RL, Arap W, Pasqualini R. Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes. Proc Natl Acad Sci U S A. 2016 Nov 08; 113(45):12780-12785. PMID: 27791177.
    Citations: 4     Fields:    
  19. Ropper AE, Zeng X, Haragopal H, Anderson JE, Aljuboori Z, Han I, Abd-El-Barr M, Lee HJ, Sidman RL, Snyder EY, Viapiano MS, Kim SU, Chi JH, Teng YD. Targeted Treatment of Experimental Spinal Cord Glioma With Dual Gene-Engineered Human Neural Stem Cells. Neurosurgery. 2016 Sep; 79(3):481-91. PMID: 26671631.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  20. Cardó-Vila M, Marchiò S, Sato M, Staquicini FI, Smith TL, Bronk JK, Yin G, Zurita AJ, Sun M, Behrens C, Sidman RL, Lee JJ, Hong WK, Wistuba II, Arap W, Pasqualini R. Interleukin-11 Receptor Is a Candidate Target for Ligand-Directed Therapy in Lung Cancer: Analysis of Clinical Samples and BMTP-11 Preclinical Activity. Am J Pathol. 2016 08; 186(8):2162-2170. PMID: 27317903.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  21. Marchiò S, Sidman RL, Arap W, Pasqualini R. Brain endothelial cell-targeted gene therapy of neurovascular disorders. EMBO Mol Med. 2016 06; 8(6):592-4. PMID: 27189170.
    Citations: 1     Fields:    Translation:HumansCells
  22. Abelin JG, Patel J, Lu X, Feeney CM, Fagbami L, Creech AL, Hu R, Lam D, Davison D, Pino L, Qiao JW, Kuhn E, Officer A, Li J, Abbatiello S, Subramanian A, Sidman R, Snyder E, Carr SA, Jaffe JD. Reduced-representation Phosphosignatures Measured by Quantitative Targeted MS Capture Cellular States and Enable Large-scale Comparison of Drug-induced Phenotypes. Mol Cell Proteomics. 2016 05; 15(5):1622-41. PMID: 26912667.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  23. Smith TL, Yuan Z, Cardó-Vila M, Sanchez Claros C, Adem A, Cui MH, Branch CA, Gelovani JG, Libutti SK, Sidman RL, Pasqualini R, Arap W. AAVP displaying octreotide for ligand-directed therapeutic transgene delivery in neuroendocrine tumors of the pancreas. Proc Natl Acad Sci U S A. 2016 Mar 01; 113(9):2466-71. PMID: 26884209.
    Citations: 4     Fields:    Translation:AnimalsCells
  24. Dondossola E, Dobroff AS, Marchiò S, Cardó-Vila M, Hosoya H, Libutti SK, Corti A, Sidman RL, Arap W, Pasqualini R. Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors. Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8):2223-8. PMID: 26858439.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  25. Hosoya H, Dobroff AS, Driessen WH, Cristini V, Brinker LM, Staquicini FI, Cardó-Vila M, D'Angelo S, Ferrara F, Proneth B, Lin YS, Dunphy DR, Dogra P, Melancon MP, Stafford RJ, Miyazono K, Gelovani JG, Kataoka K, Brinker CJ, Sidman RL, Arap W, Pasqualini R. Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release. Proc Natl Acad Sci U S A. 2016 Feb 16; 113(7):1877-82. PMID: 26839407.
    Citations: 8     Fields:    Translation:Animals
  26. Yao VJ, D'Angelo S, Butler KS, Theron C, Smith TL, Marchiò S, Gelovani JG, Sidman RL, Dobroff AS, Brinker CJ, Bradbury ARM, Arap W, Pasqualini R. Ligand-targeted theranostic nanomedicines against cancer. J Control Release. 2016 10 28; 240:267-286. PMID: 26772878.
    Citations: 10     Fields:    Translation:Humans
  27. Sidman RL, Li J, Lawrence M, Hu W, Musso GF, Giordano RJ, Cardó-Vila M, Pasqualini R, Arap W. The peptidomimetic Vasotide targets two retinal VEGF receptors and reduces pathological angiogenesis in murine and nonhuman primate models of retinal disease. Sci Transl Med. 2015 Oct 14; 7(309):309ra165. PMID: 26468327.
    Citations: 8     Fields:    Translation:HumansAnimals
  28. Salameh A, Lee AK, Cardó-Vila M, Nunes DN, Efstathiou E, Staquicini FI, Dobroff AS, Marchiò S, Navone NM, Hosoya H, Lauer RC, Wen S, Salmeron CC, Hoang A, Newsham I, Lima LA, Carraro DM, Oliviero S, Kolonin MG, Sidman RL, Do KA, Troncoso P, Logothetis CJ, Brentani RR, Calin GA, Cavenee WK, Dias-Neto E, Pasqualini R, Arap W. PRUNE2 is a human prostate cancer suppressor regulated by the intronic long noncoding RNA PCA3. Proc Natl Acad Sci U S A. 2015 Jul 07; 112(27):8403-8. PMID: 26080435.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  29. Dodge JC, Treleaven CM, Pacheco J, Cooper S, Bao C, Abraham M, Cromwell M, Sardi SP, Chuang WL, Sidman RL, Cheng SH, Shihabuddin LS. Glycosphingolipids are modulators of disease pathogenesis in amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 2015 Jun 30; 112(26):8100-5. PMID: 26056266.
    Citations: 7     Fields:    Translation:HumansAnimals
  30. Mandelin J, Cardó-Vila M, Driessen WH, Mathew P, Navone NM, Lin SH, Logothetis CJ, Rietz AC, Dobroff AS, Proneth B, Sidman RL, Pasqualini R, Arap W. Selection and identification of ligand peptides targeting a model of castrate-resistant osteogenic prostate cancer and their receptors. Proc Natl Acad Sci U S A. 2015 Mar 24; 112(12):3776-81. PMID: 25762070.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  31. Nunes DN, Dias-Neto E, Cardó-Vila M, Edwards JK, Dobroff AS, Giordano RJ, Mandelin J, Brentani HP, Hasselgren C, Yao VJ, Marchiò S, Pereira CA, Passetti F, Calin GA, Sidman RL, Arap W, Pasqualini R. Synchronous down-modulation of miR-17 family members is an early causative event in the retinal angiogenic switch. Proc Natl Acad Sci U S A. 2015 Mar 24; 112(12):3770-5. PMID: 25775553.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  32. Mintz PJ, Rietz AC, Cardó-Vila M, Ozawa MG, Dondossola E, Do KA, Kim J, Troncoso P, Logothetis CJ, Sidman RL, Pasqualini R, Arap W. Discovery and horizontal follow-up of an autoantibody signature in human prostate cancer. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2515-20. PMID: 25675522.
    Citations: 14     Fields:    Translation:HumansCells
  33. Christianson DR, Dobroff AS, Proneth B, Zurita AJ, Salameh A, Dondossola E, Makino J, Bologa CG, Smith TL, Yao VJ, Calderone TL, O'Connell DJ, Oprea TI, Kataoka K, Cahill DJ, Gershenwald JE, Sidman RL, Arap W, Pasqualini R. Ligand-directed targeting of lymphatic vessels uncovers mechanistic insights in melanoma metastasis. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2521-6. PMID: 25659743.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  34. Dobroff AS, Rangel R, Guzman-Roja L, Salmeron CC, Gelovani JG, Sidman RL, Bologa CG, Oprea TI, Brinker CJ, Pasqualini R, Arap W. Ligand-directed profiling of organelles with internalizing phage libraries. Curr Protoc Protein Sci. 2015 Feb 02; 79:30.4.1-30. PMID: 25640897.
    Citations: 1     Fields:    Translation:HumansCells
  35. Staquicini FI, Qian MD, Salameh A, Dobroff AS, Edwards JK, Cimino DF, Moeller BJ, Kelly P, Nunez MI, Tang X, Liu DD, Lee JJ, Hong WK, Ferrara F, Bradbury AR, Lobb RR, Edelman MJ, Sidman RL, Wistuba II, Arap W, Pasqualini R. Receptor tyrosine kinase EphA5 is a functional molecular target in human lung cancer. J Biol Chem. 2015 Mar 20; 290(12):7345-59. PMID: 25623065.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  36. Dondossola E, Corti A, Sidman RL, Arap W, Pasqualini R. Bone marrow-derived CD13+ cells sustain tumor progression: A potential non-malignant target for anticancer therapy. Oncoimmunology. 2014; 3:e27716. PMID: 25339996.
    Citations: 2     
  37. Dondossola E, Rangel R, Guzman-Rojas L, Barbu EM, Hosoya H, St John LS, Molldrem JJ, Corti A, Sidman RL, Arap W, Pasqualini R. CD13-positive bone marrow-derived myeloid cells promote angiogenesis, tumor growth, and metastasis. Proc Natl Acad Sci U S A. 2013 Dec 17; 110(51):20717-22. PMID: 24297924.
    Citations: 10     Fields:    Translation:AnimalsCells
  38. Karjalainen K, Pasqualini R, Cortes JE, Kornblau SM, Lichtiger B, O'Brien S, Kantarjian HM, Sidman RL, Arap W, Koivunen E. Design, development, and validation of a high-throughput drug-screening assay for targeting of human leukemia. Cancer. 2014 Feb 15; 120(4):589-602. PMID: 24496871.
    Citations:    Fields:    Translation:Humans
  39. Barbu EM, Shirazi F, McGrath DM, Albert N, Sidman RL, Pasqualini R, Arap W, Kontoyiannis DP. An antimicrobial peptidomimetic induces Mucorales cell death through mitochondria-mediated apoptosis. PLoS One. 2013; 8(10):e76981. PMID: 24098573.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  40. Rangel R, Dobroff AS, Guzman-Rojas L, Salmeron CC, Gelovani JG, Sidman RL, Pasqualini R, Arap W. Targeting mammalian organelles with internalizing phage (iPhage) libraries. Nat Protoc. 2013 Oct; 8(10):1916-39. PMID: 24030441.
    Citations: 3     Fields:    Translation:AnimalsCells
  41. Dodge JC, Treleaven CM, Fidler JA, Tamsett TJ, Bao C, Searles M, Taksir TV, Misra K, Sidman RL, Cheng SH, Shihabuddin LS. Metabolic signatures of amyotrophic lateral sclerosis reveal insights into disease pathogenesis. Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26):10812-7. PMID: 23754387.
    Citations: 23     Fields:    Translation:HumansAnimals
  42. Li J, Yu L, Gu X, Ma Y, Pasqualini R, Arap W, Snyder EY, Sidman RL. Tissue plasminogen activator regulates Purkinje neuron development and survival. Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26):E2410-9. PMID: 23674688.
    Citations: 11     Fields:    Translation:AnimalsCells
  43. Yu D, Thakor DK, Han I, Ropper AE, Haragopal H, Sidman RL, Zafonte R, Schachter SC, Teng YD. Alleviation of chronic pain following rat spinal cord compression injury with multimodal actions of huperzine A. Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8):E746-55. PMID: 23386718.
    Citations: 11     Fields:    Translation:Animals
  44. McGrath DM, Barbu EM, Driessen WH, Lasco TM, Tarrand JJ, Okhuysen PC, Kontoyiannis DP, Sidman RL, Pasqualini R, Arap W. Mechanism of action and initial evaluation of a membrane active all-D-enantiomer antimicrobial peptidomimetic. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3477-82. PMID: 23345420.
    Citations: 10     Fields:    Translation:Cells
  45. Sardi SP, Clarke J, Viel C, Chan M, Tamsett TJ, Treleaven CM, Bu J, Sweet L, Passini MA, Dodge JC, Yu WH, Sidman RL, Cheng SH, Shihabuddin LS. Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3537-42. PMID: 23297226.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  46. Teng YD, Benn SC, Kalkanis SN, Shefner JM, Onario RC, Cheng B, Lachyankar MB, Marconi M, Li J, Yu D, Han I, Maragakis NJ, Lládo J, Erkmen K, Redmond DE, Sidman RL, Przedborski S, Rothstein JD, Brown RH, Snyder EY. Multimodal actions of neural stem cells in a mouse model of ALS: a meta-analysis. Sci Transl Med. 2012 Dec 19; 4(165):165ra164. PMID: 23253611.
    Citations: 27     Fields:    Translation:AnimalsCells
  47. Rangel R, Guzman-Rojas L, le Roux LG, Staquicini FI, Hosoya H, Barbu EM, Ozawa MG, Nie J, Dunner K, Langley RR, Sage EH, Koivunen E, Gelovani JG, Lobb RR, Sidman RL, Pasqualini R, Arap W. Combinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells. Nat Commun. 2012 Apr 17; 3:788. PMID: 22510693.
    Citations: 13     Fields:    Translation:HumansCells
  48. Guzman-Rojas L, Rangel R, Salameh A, Edwards JK, Dondossola E, Kim YG, Saghatelian A, Giordano RJ, Kolonin MG, Staquicini FI, Koivunen E, Sidman RL, Arap W, Pasqualini R. Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):1637-42. PMID: 22307623.
    Citations: 20     Fields:    Translation:AnimalsCells
  49. Teng YD, Yu D, Ropper AE, Li J, Kabatas S, Wakeman DR, Wang J, Sullivan MP, Redmond DE, Langer R, Snyder EY, Sidman RL. Functional multipotency of stem cells: a conceptual review of neurotrophic factor-based evidence and its role in translational research. Curr Neuropharmacol. 2011 Dec; 9(4):574-85. PMID: 22654717.
    Citations: 11     Fields:    
  50. Staquicini FI, Cardó-Vila M, Kolonin MG, Trepel M, Edwards JK, Nunes DN, Sergeeva A, Efstathiou E, Sun J, Almeida NF, Tu SM, Botz GH, Wallace MJ, O'Connell DJ, Krajewski S, Gershenwald JE, Molldrem JJ, Flamm AL, Koivunen E, Pentz RD, Dias-Neto E, Setubal JC, Cahill DJ, Troncoso P, Do KA, Logothetis CJ, Sidman RL, Pasqualini R, Arap W. Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):18637-42. PMID: 22049339.
    Citations: 20     Fields:    Translation:HumansCells
  51. Sardi SP, Clarke J, Kinnecom C, Tamsett TJ, Li L, Stanek LM, Passini MA, Grabowski GA, Schlossmacher MG, Sidman RL, Cheng SH, Shihabuddin LS. CNS expression of glucocerebrosidase corrects alpha-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):12101-6. PMID: 21730160.
    Citations: 77     Fields:    Translation:AnimalsCells
  52. Kim KS, Lee HJ, Jeong HS, Li J, Teng YD, Sidman RL, Snyder EY, Kim SU. Self-renewal induced efficiently, safely, and effective therapeutically with one regulatable gene in a human somatic progenitor cell. Proc Natl Acad Sci U S A. 2011 Mar 22; 108(12):4876-81. PMID: 21378266.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  53. Moeller BJ, Sidman RL, Pasqualini R, Arap W. Discovery of DNA repair inhibitors by combinatorial library profiling. Cancer Res. 2011 Mar 01; 71(5):1816-24. PMID: 21343400.
    Citations: 2     Fields:    Translation:HumansCells
  54. Imitola J, Côté D, Rasmussen S, Xie XS, Liu Y, Chitnis T, Sidman RL, Lin CP, Khoury SJ. Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice. J Biomed Opt. 2011 Feb; 16(2):021109. PMID: 21361672.
    Citations: 19     Fields:    Translation:AnimalsCells
  55. Staquicini FI, Ozawa MG, Moya CA, Driessen WH, Barbu EM, Nishimori H, Soghomonyan S, Flores LG, Liang X, Paolillo V, Alauddin MM, Basilion JP, Furnari FB, Bogler O, Lang FF, Aldape KD, Fuller GN, Höök M, Gelovani JG, Sidman RL, Cavenee WK, Pasqualini R, Arap W. Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. J Clin Invest. 2011 Jan; 121(1):161-73. PMID: 21183793.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  56. Yang WW, Sidman RL, Taksir TV, Treleaven CM, Fidler JA, Cheng SH, Dodge JC, Shihabuddin LS. Relationship between neuropathology and disease progression in the SOD1(G93A) ALS mouse. Exp Neurol. 2011 Feb; 227(2):287-95. PMID: 21145892.
    Citations: 13     Fields:    Translation:HumansAnimals
  57. Li J, Gu X, Ma Y, Calicchio ML, Kong D, Teng YD, Yu L, Crain AM, Vartanian TK, Pasqualini R, Arap W, Libermann TA, Snyder EY, Sidman RL. Nna1 mediates Purkinje cell dendritic development via lysyl oxidase propeptide and NF-?B signaling. Neuron. 2010 Oct 06; 68(1):45-60. PMID: 20920790.
    Citations: 32     Fields:    Translation:AnimalsCells
  58. Staquicini FI, Sidman RL, Arap W, Pasqualini R. Phage display technology for stem cell delivery and systemic therapy. Adv Drug Deliv Rev. 2010 Sep 30; 62(12):1213-6. PMID: 20932865.
    Citations: 7     Fields:    Translation:HumansCells
  59. Chuang N, Mori S, Yamamoto A, Jiang H, Ye X, Xu X, Richards LJ, Nathans J, Miller MI, Toga AW, Sidman RL, Zhang J. An MRI-based atlas and database of the developing mouse brain. Neuroimage. 2011 Jan 01; 54(1):80-9. PMID: 20656042.
    Citations: 44     Fields:    Translation:AnimalsCells
  60. Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE, Wu C, Wunsch C, Zoback ML. Climate change and the integrity of science. Science. 2010 May 07; 328(5979):689-90. PMID: 20448167.
    Citations: 6     Fields:    Translation:Humans
  61. Giordano RJ, Cardó-Vila M, Salameh A, Anobom CD, Zeitlin BD, Hawke DH, Valente AP, Almeida FC, Nör JE, Sidman RL, Pasqualini R, Arap W. From combinatorial peptide selection to drug prototype (I): targeting the vascular endothelial growth factor receptor pathway. Proc Natl Acad Sci U S A. 2010 Mar 16; 107(11):5112-7. PMID: 20190181.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  62. Cardó-Vila M, Giordano RJ, Sidman RL, Bronk LF, Fan Z, Mendelsohn J, Arap W, Pasqualini R. From combinatorial peptide selection to drug prototype (II): targeting the epidermal growth factor receptor pathway. Proc Natl Acad Sci U S A. 2010 Mar 16; 107(11):5118-23. PMID: 20190183.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  63. Jäderstad J, Jäderstad LM, Li J, Chintawar S, Salto C, Pandolfo M, Ourednik V, Teng YD, Sidman RL, Arenas E, Snyder EY, Herlenius E. Communication via gap junctions underlies early functional and beneficial interactions between grafted neural stem cells and the host. Proc Natl Acad Sci U S A. 2010 Mar 16; 107(11):5184-9. PMID: 20147621.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  64. Aggarwal M, Zhang J, Miller MI, Sidman RL, Mori S. Magnetic resonance imaging and micro-computed tomography combined atlas of developing and adult mouse brains for stereotaxic surgery. Neuroscience. 2009 Sep 15; 162(4):1339-50. PMID: 19490934.
    Citations: 32     Fields:    Translation:Animals
  65. Staquicini FI, Dias-Neto E, Li J, Snyder EY, Sidman RL, Pasqualini R, Arap W. Discovery of a functional protein complex of netrin-4, laminin gamma1 chain, and integrin alpha6beta1 in mouse neural stem cells. Proc Natl Acad Sci U S A. 2009 Feb 24; 106(8):2903-8. PMID: 19193855.
    Citations: 37     Fields:    Translation:AnimalsCells
  66. Khakoo AY, Sidman RL, Pasqualini R, Arap W. Does the renin-angiotensin system participate in regulation of human vasculogenesis and angiogenesis? Cancer Res. 2008 Nov 15; 68(22):9112-5. PMID: 19010879.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  67. Macauley SL, Sidman RL, Schuchman EH, Taksir T, Stewart GR. Neuropathology of the acid sphingomyelinase knockout mouse model of Niemann-Pick A disease including structure-function studies associated with cerebellar Purkinje cell degeneration. Exp Neurol. 2008 Dec; 214(2):181-92. PMID: 18778708.
    Citations: 15     Fields:    Translation:AnimalsCells
  68. Sidman RL, Taksir T, Fidler J, Zhao M, Dodge JC, Passini MA, Raben N, Thurberg BL, Cheng SH, Shihabuddin LS. Temporal neuropathologic and behavioral phenotype of 6neo/6neo Pompe disease mice. J Neuropathol Exp Neurol. 2008 Aug; 67(8):803-18. PMID: 18648322.
    Citations: 28     Fields:    Translation:Animals
  69. Ozawa MG, Zurita AJ, Dias-Neto E, Nunes DN, Sidman RL, Gelovani JG, Arap W, Pasqualini R. Beyond receptor expression levels: the relevance of target accessibility in ligand-directed pharmacodelivery systems. Trends Cardiovasc Med. 2008 May; 18(4):126-32. PMID: 18555185.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  70. Cameron JS, Alexopoulou L, Sloane JA, DiBernardo AB, Ma Y, Kosaras B, Flavell R, Strittmatter SM, Volpe J, Sidman R, Vartanian T. Toll-like receptor 3 is a potent negative regulator of axonal growth in mammals. J Neurosci. 2007 Nov 21; 27(47):13033-41. PMID: 18032677.
    Citations: 66     Fields:    Translation:AnimalsCells
  71. Noebels JL, Sidman RL. Persistent hypersynchronization of neocortical neurons in the mocha mutant of mouse. J Neurogenet. 2007 Oct-Dec; 21(4):253-6. PMID: 18161587.
    Citations:    Fields:    
  72. Ma Y, Haynes RL, Sidman RL, Vartanian T. TLR8: an innate immune receptor in brain, neurons and axons. Cell Cycle. 2007 Dec 01; 6(23):2859-68. PMID: 18000403.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  73. Li J, Cui Z, Zhao S, Sidman RL. Unique glycerophospholipid signature in retinal stem cells correlates with enzymatic functions of diverse long-chain acyl-CoA synthetases. Stem Cells. 2007 Nov; 25(11):2864-73. PMID: 17690180.
    Citations: 3     Fields:    Translation:AnimalsCells
  74. Redmond DE, Bjugstad KB, Teng YD, Ourednik V, Ourednik J, Wakeman DR, Parsons XH, Gonzalez R, Blanchard BC, Kim SU, Gu Z, Lipton SA, Markakis EA, Roth RH, Elsworth JD, Sladek JR, Sidman RL, Snyder EY. Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells. Proc Natl Acad Sci U S A. 2007 Jul 17; 104(29):12175-80. PMID: 17586681.
    Citations: 112     Fields:    Translation:HumansAnimalsCells
  75. Lahdenranta J, Sidman RL, Pasqualini R, Arap W. Treatment of hypoxia-induced retinopathy with targeted proapoptotic peptidomimetic in a mouse model of disease. FASEB J. 2007 Oct; 21(12):3272-8. PMID: 17513561.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  76. CHUANG N, ZHANG J, LI J, XU B, SENFT S, SIDMAN RL AND MORI S. Three dimensional atlas of developing mouse brains based on diffusion tensor imaging. Internat. Soc. Magnetic Resonance in Medicine, Berlin. 2007.
  77. Rangel R, Sun Y, Guzman-Rojas L, Ozawa MG, Sun J, Giordano RJ, Van Pelt CS, Tinkey PT, Behringer RR, Sidman RL, Arap W, Pasqualini R. Impaired angiogenesis in aminopeptidase N-null mice. Proc Natl Acad Sci U S A. 2007 Mar 13; 104(11):4588-93. PMID: 17360568.
    Citations: 36     Fields:    Translation:Animals
  78. Sidman RL, Li J, Stewart GR, Clarke J, Yang W, Snyder EY, Shihabuddin LS. Injection of mouse and human neural stem cells into neonatal Niemann-Pick A model mice. Brain Res. 2007 Apr 06; 1140:195-204. PMID: 17289003.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  79. Teng YD, Liao WL, Choi H, Konya D, Sabharwal S, Langer R, Sidman RL, Snyder EY, Frontera WR. Physical activity-mediated functional recovery after spinal cord injury: potential roles of neural stem cells. Regen Med. 2006 Nov; 1(6):763-76. PMID: 17465758.
    Citations: 10     Fields:    Translation:HumansCells
  80. Ma Y, Li J, Chiu I, Wang Y, Sloane JA, Lü J, Kosaras B, Sidman RL, Volpe JJ, Vartanian T. Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis. J Cell Biol. 2006 Oct 23; 175(2):209-15. PMID: 17060494.
    Citations: 89     Fields:    Translation:AnimalsCells
  81. Li J, Imitola J, Snyder EY, Sidman RL. Neural stem cells rescue nervous purkinje neurons by restoring molecular homeostasis of tissue plasminogen activator and downstream targets. J Neurosci. 2006 Jul 26; 26(30):7839-48. PMID: 16870729. </