Harvard Catalyst Profiles
Contact, publication, and social network information about Harvard faculty and fellows.
Home
About
Overview
Open Source Software
Help
History (1)
Kieff, Elliott
See All Pages
Find People
Find Everything
Login
to
edit your profile
(add a photo, education, awards, etc.), search
student opportunities
, and
create reports
.
Edit My Profile
My Person List (
0
)
Opportunity Search
Return to Top
Elliott D. Kieff, Ph.D., M.D.
Title
Harriet Ryan Albee Professor of Medicine, Emeritus
Institution
Brigham and Women's Hospital
Department
Emeritus
Address
Channing Laboratory
8th FL, Medicine/Micro and Mol Genetics
181 Longwood Ave
Boston MA 02115
Phone
617/525-4252
vCard
Download vCard
(
login for email
)
research activities and funding
|
selected publications
|
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
R01AI123420
(ZHAO, BO)
Mar 1, 2016 - Mar 31, 2026
NIH
Targeting Epstein-Barr Virus Super-Enhancer
Role: Principal Investigator
R01CA170023
(ZHAO, BO)
Mar 15, 2013 - Feb 28, 2018
NIH
Roles of Epstein-Barr virus nuclear antigens 2 and LP in B cell proliferation
Role: Principal Investigator
R01CA131354
(KIEFF, ELLIOTT D)
Dec 10, 2008 - Nov 30, 2013
NIH
Inhibitors of Epstein-Barr Virus Nuclear Protein 1 Mediated Latent Infection
Role: Principal Investigator
R03NS050788
(KIEFF, ELLIOTT D)
Sep 30, 2004 - Sep 29, 2005
NIH
Screening of Epstein Barr Virus Replication (RMI)
Role: Principal Investigator
R01CA085180
(KIEFF, ELLIOTT D)
Sep 20, 2000 - Nov 30, 2016
NIH
Epstein-Barr Virus LMP1-Mediated Oncogenecity
Role: Principal Investigator
R13CA062927
(KIEFF, ELLIOTT D)
Feb 1, 1994 - Jan 31, 1995
NIH
CONFERENCE ON HUMAN TUMOR VIRUSES
Role: Principal Investigator
R01CA047006
(ZHAO, BO)
Jun 1, 1987 - Jul 31, 2022
NIH
Epstein-Barr Virus Nuclear Protein B Cell Growth Transformation
Role: Principal Investigator
R35CA047006
(KIEFF, ELLIOTT D)
Jun 1, 1987 - Mar 31, 2002
NIH
MOLECULAR BIOLOGY OF EPSTEIN-BARR VIRUS INFECTION
Role: Principal Investigator
R37CA044165
(KIEFF, ELLIOTT D)
Jan 1, 1987 - May 31, 1987
NIH
EBV MEMBRANE PROTEIN: TRANSFORMATION AND LATENCY
Role: Principal Investigator
T32CA009031
(KIEFF, ELLIOTT D)
Jul 1, 1980 - May 31, 2011
NIH
VIRUS-HOST INTERACTIONS IN CANCER
Role: Principal Investigator
R01CA017281
(KIEFF, ELLIOTT D)
Jun 1, 1978 - May 31, 1988
NIH
EBV INTERACTION WITH LYMPHOBLASTS IN VITRO AND IN VIVO
Role: Principal Investigator
T32AI007099
(R0IZMAN, BERNARD)
Jul 1, 1977 - Aug 31, 1989
NIH
INFECTIOUS DISEASES
Role: Co-Principal Investigator
P01CA019264
(ULTMANN, JOHN E)
Jun 30, 1976 - Jun 30, 1990
NIH/NCI
CORE--VIRAL ONCOLOGY
Role: Co-Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Zhang H, Li Y, Wang HB, Zhang A, Chen ML, Fang ZX, Dong XD, Li SB, Du Y, Xiong D, He JY, Li MZ, Liu YM, Zhou AJ, Zhong Q, Zeng YX,
Kieff E
, Zhang Z,
Gewurz BE
, Zhao B, Zeng MS. Author Correction: Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry. Nat Microbiol. 2018 Sep; 3(9):1075.
PMID:
29679064
.
Citations:
4
Fields:
Mic
Microbiology
Par
Parasitology
Vir
Virology
Zhang H, Li Y, Wang HB, Zhang A, Chen ML, Fang ZX, Dong XD, Li SB, Du Y, Xiong D, He JY, Li MZ, Liu YM, Zhou AJ, Zhong Q, Zeng YX,
Kieff E
, Zhang Z,
Gewurz BE
,
Zhao B
, Zeng MS. Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry. Nat Microbiol. 2018 02; 3(2):1-8.
PMID:
29292383
.
Citations:
90
Fields:
Mic
Microbiology
Par
Parasitology
Vir
Virology
Translation:
Humans
Animals
Cells
Jiang S
, Zhou H, Liang J, Gerdt C, Wang C, Ke L, Schmidt SCS, Narita Y, Ma Y, Wang S, Colson T,
Gewurz B
, Li G,
Kieff E
,
Zhao B
. The Epstein-Barr Virus Regulome in Lymphoblastoid Cells. Cell Host Microbe. 2017 Oct 11; 22(4):561-573.e4.
PMID:
29024646
; PMCID:
PMC5662195
.
Citations:
47
Fields:
Mic
Microbiology
Translation:
Humans
Cells
Ersing I, Nobre L, Wang LW, Soday L, Ma Y,
Paulo JA
, Narita Y, Ashbaugh CW, Jiang C, Grayson NE,
Kieff E
,
Gygi SP
, Weekes MP,
Gewurz BE
. A Temporal Proteomic Map of Epstein-Barr Virus Lytic Replication in B Cells. Cell Rep. 2017 05 16; 19(7):1479-1493.
PMID:
28514666
.
Citations:
37
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Minamitani T, Ma Y, Zhou H, Kida H, Tsai CY, Obana M, Okuzaki D, Fujio Y, Kumanogoh A,
Zhao B
, Kikutani H,
Kieff E
,
Gewurz BE
, Yasui T. Mouse model of Epstein-Barr virus LMP1- and LMP2A-driven germinal center B-cell lymphoproliferative disease. Proc Natl Acad Sci U S A. 2017 05 02; 114(18):4751-4756.
PMID:
28351978
; PMCID:
PMC5422827
.
Citations:
22
Fields:
Sci
Science
Translation:
Animals
Cells
Liang J, Zhou H, Gerdt C, Tan M, Colson T,
Kaye KM
,
Kieff E
,
Zhao B
. Epstein-Barr virus super-enhancer eRNAs are essential for MYC oncogene expression and lymphoblast proliferation. Proc Natl Acad Sci U S A. 2016 12 06; 113(49):14121-14126.
PMID:
27864512
; PMCID:
PMC5150416
.
Citations:
45
Fields:
Sci
Science
Translation:
Humans
Cells
Shen CL, Liu CD, You RI, Ching YH, Liang J, Ke L, Chen YL, Chen HC, Hsu HJ, Liou JW,
Kieff E
, Peng CW. Ribosome Protein L4 is essential for Epstein-Barr Virus Nuclear Antigen 1 function. Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8):2229-34.
PMID:
26858444
; PMCID:
PMC4776490
.
Citations:
13
Fields:
Sci
Science
Translation:
Humans
Cells
Minamitani T, Yasui T, Ma Y,
Zhou H
, Okuzaki D, Tsai CY, Sakakibara S,
Gewurz BE
,
Kieff E
, Kikutani H. Evasion of affinity-based selection in germinal centers by Epstein-Barr virus LMP2A. Proc Natl Acad Sci U S A. 2015 Sep 15; 112(37):11612-7.
PMID:
26305967
; PMCID:
PMC4577157
.
Citations:
22
Fields:
Sci
Science
Translation:
Animals
Cells
Xiong D, Du Y, Wang HB,
Zhao B
, Zhang H, Li Y, Hu LJ, Cao JY, Zhong Q, Liu WL, Li MZ, Zhu XF, Tsao SW, Hutt-Fletcher LM, Song E, Zeng YX,
Kieff E
, Zeng MS. Nonmuscle myosin heavy chain IIA mediates Epstein-Barr virus infection of nasopharyngeal epithelial cells. Proc Natl Acad Sci U S A. 2015 Sep 01; 112(35):11036-41.
PMID:
26290577
; PMCID:
PMC4568263
.
Citations:
40
Fields:
Sci
Science
Translation:
Humans
Cells
Zhou H
, Schmidt SC,
Jiang S
, Willox B, Bernhardt K, Liang J, Johannsen EC,
Kharchenko P
,
Gewurz BE
,
Kieff E
,
Zhao B
. Epstein-Barr virus oncoprotein super-enhancers control B cell growth. Cell Host Microbe. 2015 Feb 11; 17(2):205-16.
PMID:
25639793
; PMCID:
PMC4539236
.
Citations:
83
Fields:
Mic
Microbiology
Translation:
Cells
Kang MS,
Kieff E
. Epstein-Barr virus latent genes. Exp Mol Med. 2015 Jan 23; 47:e131.
PMID:
25613728
; PMCID:
PMC4314583
.
Citations:
129
Fields:
Bio
Biochemistry
Mol
Molecular Biology
Translation:
Humans
Cells
Schmidt SC,
Jiang S
,
Zhou H
, Willox B, Holthaus AM,
Kharchenko PV
, Johannsen EC,
Kieff E
,
Zhao B
. Epstein-Barr virus nuclear antigen 3A partially coincides with EBNA3C genome-wide and is tethered to DNA through BATF complexes. Proc Natl Acad Sci U S A. 2015 Jan 13; 112(2):554-9.
PMID:
25540416
; PMCID:
PMC4299249
.
Citations:
30
Fields:
Sci
Science
Translation:
Humans
Cells
Zhao B
, Barrera LA, Ersing I, Willox B, Schmidt SC, Greenfeld H,
Zhou H
, Mollo SB, Shi TT, Takasaki K,
Jiang S
, Cahir-McFarland E, Kellis M,
Bulyk ML
,
Kieff E
,
Gewurz BE
. The NF-?B genomic landscape in lymphoblastoid B cells. Cell Rep. 2014 Sep 11; 8(5):1595-606.
PMID:
25159142
.
Citations:
87
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Cells
Hadweh P, Habelhah H,
Kieff E
, Mosialos G, Hatzivassiliou E. The PP4R1 subunit of protein phosphatase PP4 targets TRAF2 and TRAF6 to mediate inhibition of NF-?B activation. Cell Signal. 2014 Dec; 26(12):2730-7.
PMID:
25134449
.
Citations:
12
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Lee EK, Kim SY, Noh KW, Joo EH,
Zhao B
,
Kieff E
, Kang MS. Small molecule inhibition of Epstein-Barr virus nuclear antigen-1 DNA binding activity interferes with replication and persistence of the viral genome. Antiviral Res. 2014 Apr; 104:73-83.
PMID:
24486954
.
Citations:
10
Fields:
Ant
Anti-Infective Agents
Vir
Virology
Translation:
Humans
Cells
Jiang S
, Willox B,
Zhou H
, Holthaus AM, Wang A, Shi TT, Maruo S,
Kharchenko PV
, Johannsen EC,
Kieff E
,
Zhao B
. Epstein-Barr virus nuclear antigen 3C binds to BATF/IRF4 or SPI1/IRF4 composite sites and recruits Sin3A to repress CDKN2A. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):421-6.
PMID:
24344258
.
Citations:
51
Fields:
Sci
Science
Translation:
Humans
Cells
Chen YL, Liu CD, Cheng CP,
Zhao B
, Hsu HJ, Shen CL, Chiu SJ,
Kieff E
, Peng CW. Nucleolin is important for Epstein-Barr virus nuclear antigen 1-mediated episome binding, maintenance, and transcription. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):243-8.
PMID:
24344309
.
Citations:
19
Fields:
Sci
Science
Translation:
Humans
Cells
Kim JE, Kim SY, Lim SY,
Kieff E
, Song YJ. Role of Ca2+/calmodulin-dependent kinase II-IRAK1 interaction in LMP1-induced NF-?B activation. Mol Cell Biol. 2014 Feb; 34(3):325-34.
PMID:
24248603
.
Citations:
14
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Portal D,
Zhou H
,
Zhao B
,
Kharchenko PV
, Lowry E, Wong L,
Quackenbush J
, Holloway D,
Jiang S
, Lu Y,
Kieff E
. Epstein-Barr virus nuclear antigen leader protein localizes to promoters and enhancers with cell transcription factors and EBNA2. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):18537-42.
PMID:
24167291
.
Citations:
31
Fields:
Sci
Science
Translation:
Animals
Cells
Zhou X,
Gewurz BE
, Ritchie JM, Takasaki K, Greenfeld H,
Kieff E
, Davis BM,
Waldor MK
. A Vibrio parahaemolyticus T3SS effector mediates pathogenesis by independently enabling intestinal colonization and inhibiting TAK1 activation. Cell Rep. 2013 May 30; 3(5):1690-702.
PMID:
23623501
.
Citations:
37
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Liu CD, Cheng CP, Fang JS, Chen LC,
Zhao B
,
Kieff E
, Peng CW. Modulation of Epstein-Barr virus nuclear antigen 2-dependent transcription by protein arginine methyltransferase 5. Biochem Biophys Res Commun. 2013 Jan 18; 430(3):1097-102.
PMID:
23261437
.
Citations:
8
Fields:
Bio
Biochemistry
Bio
Biophysics
Translation:
Humans
Cells
Liu CD, Chen YL, Min YL,
Zhao B
, Cheng CP, Kang MS, Chiu SJ,
Kieff E
, Peng CW. The nuclear chaperone nucleophosmin escorts an Epstein-Barr Virus nuclear antigen to establish transcriptional cascades for latent infection in human B cells. PLoS Pathog. 2012; 8(12):e1003084.
PMID:
23271972
; PMCID:
PMC3521654
.
Citations:
16
Fields:
Mic
Microbiology
Translation:
Humans
Cells
Rozenblatt-Rosen O,
Deo RC
, Padi M,
Adelmant G
, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR,
Chen AA
, Cheng J, Correll M, Duarte M, Fan C, Feltkamp MC,
Ficarro SB
, Franchi R, Garg BK, Gulbahce N, Hao T, Holthaus AM, James R, Korkhin A, Litovchick L, Mar JC,
Pak TR
, Rabello S, Rubio R, Shen Y, Singh S, Spangle JM, Tasan M, Wanamaker S, Webber JT, Roecklein-Canfield J, Johannsen E, Barabási AL,
Beroukhim R
,
Kieff E
, Cusick ME,
Hill DE
, Münger K,
Marto JA
,
Quackenbush J
, Roth FP,
DeCaprio JA
,
Vidal M
. Interpre