Harvard Catalyst Profiles

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Matthew Langer Meyerson, M.D., Ph.D.

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Mentoring
current student opportunities
Available: 12/12/23, Expires: 12/31/40

Our laboratory offers a variety of potential M.D. student projects across our research portfolio in cancer genomics, cancer cell biology, the cancer microbiome, and cancer therapeutics. Our disease of emphasis is lung cancer but we also have research programs in colorectal cancer, glioblastoma, and pan-cancer. Potential projects include both experimental cell biology, biochemistry, genome engineering, and animal cancer models, as well as computational genomics on the somatic and germline genome and the microbiome. Each student will be paired with a senior PhD student, post-doctoral research fellow, or research scientist in our group, who will be your direct supervisor. Specific areas include: Cancer genomics: --Long-read sequencing of lung cancer genomes and transcriptomes --How does germline ancestry impact risk of lung cancer somatic mutations? Cancer cell biology: --Understanding the role of "mystery genes" mutated in lung cancer including NKX2-1, U2AF1 and CMTR2 --Studying somatic super-enhancer duplications in cancer Cancer microbiome: --Assessing the role of Fusobacterium infection in colon cancer pathogenesis Cancer therapeutics: --Targeting oncogenes: EGFR/ERBB2, telomerase, others --Targeting the cancer neo-genome with nucleic acid approaches

completed student projects
Examining associations between the expression of HLA class I molecules and the neoantigen burden
Summer, 05/29/14 - 08/31/14
Disruption of EGFR Dimerization
Summer, 06/01/06 - 08/31/06
Identifying the Inciting Pathogen in Multiple Sclerosis
Summer, 06/01/02 - 08/31/02

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R35CA197568 (MEYERSON, MATTHEW L.) Aug 1, 2015 - Jul 31, 2028
    NIH
    Lung Adenocarcinoma: From Genome Alterations to Therapeutic Discovery
    Role: Principal Investigator
  2. P01CA154303 (MEYERSON, MATTHEW L.) May 11, 2012 - Aug 31, 2022
    NIH
    Protein Kinase Therapeutic Targets for Non-Small Cell Lung Carcinoma
    Role: Principal Investigator
  3. RC2CA148317 (MEYERSON, MATTHEW L) Sep 30, 2009 - Aug 31, 2012
    NIH
    An infrastructure for cancer virus discovery from next-generation sequencing data
    Role: Principal Investigator
  4. U24CA143867 (MEYERSON, MATTHEW L.) Sep 29, 2009 - Jul 31, 2016
    NIH
    Genome Characterization Center (GCC)
    Role: Co-Principal Investigator
  5. U24CA126546 (MEYERSON, MATTHEW L) Sep 28, 2006 - Jul 31, 2011
    NIH
    Center for Cancer Genome Characterization
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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© 2024 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.