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Sandro Santagata, M.D., Ph.D.

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Overview
Sandro Santagata is an Associate Professor of Systems Biology at Harvard Medical School and an Associate Professor in the Department of Pathology at Brigham and Women’s Hospital where he is a neuropathologist. He is a member of the Ludwig Center at Harvard and the Harvard Program in Therapeutic Science, and is the Associate Director of the Laboratory of Systems Pharmacology (LSP) at Harvard Medical School (HMS). His research laboratory at BWH and the HMS LSP develops and implements methodologies to image tissues resected from cancer patients, extracting molecular information that sheds light on how cancers form and then develop their most aggressive features. With these technologies, his group investigates the biological properties of cancer tissues, the molecular systems tumor cells use to evade immune surveillance, and the ways that cancer and immune cells assemble into dynamic ecosystems with emergent properties. This rich imaging data is being made available in the form of interactive tumor atlases as part of the National Cancer Institute’s Human Tumor Atlas Network (HTAN), a consortium which is assembling 2D and 3D maps of human precancers and cancers which can be browsed and analyzed by users for research and clinical practice, to advance our understanding of cancer and to find new treatments.

Mentoring
The Role of the Ciliogenesis Gene Program in Gliomas
Summer, 02/01/15 - 09/04/15

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. U01CA284207 (PFISTER, HANSPETER) Sep 12, 2023 - Aug 31, 2026
    NIH
    Visual Analytics for Exploration and Hypothesis Generation Using Highly MultiplexedSpatial Data of Tissues and Tumors
    Role: Co-Principal Investigator
  2. R01CA279550 (TSVETKOV, PETER) Jul 8, 2023 - Jun 30, 2028
    NIH
    Mechanisms promoting copper dependent cell death in cancer
    Role: Co-Principal Investigator
  3. U2CCA233262 (SORGER, PETER KARL) Sep 30, 2018 - Jun 30, 2023
    NIH
    Pre-cancer atlases of cutaneous and hematologic origin (PATCH Center)
    Role: Co-Principal Investigator
  4. R01CA194005 (SANTAGATA, SANDRO) Aug 11, 2016 - Jul 31, 2021
    NIH
    Investigating the HSF1 Cancer Network
    Role: Principal Investigator
  5. K08NS064168 (SANTAGATA, SANDRO) Sep 1, 2008 - Oct 31, 2013
    NIH
    Heat Shock Directed Drug Discovery For The Treatment Of Gliomas
    Role: Principal Investigator

Bibliographic
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.