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Sandro Santagata, Ph.D., M.D.
Title
Associate Professor of Pathology
Institution
Brigham and Women's Hospital
Department
Pathology
Address
Brigham and Women's Hospital
HMS Department of Pathology, BTM 8002P
60 Fenwood Rd
Boston MA 02115
Phone
617/732-7510
vCard
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Other Positions
Title
Associate Professor of Systems Biology
Institution
Harvard Medical School
Department
Systems Biology
overview
|
webpage
|
completed student projects
|
research activities and funding
|
selected publications
|
Overview
overview
Sandro Santagata is an Associate Professor in the Department of Pathology at Brigham and Women’s Hospital and an Associate Professor of Systems Biology at Harvard Medical School. He practices neuropathology with a focus on the molecular pathology of brain tumors. He is a member of the Ludwig Center at Harvard, the Harvard Program in Therapeutic Science, and the HMS Laboratory of Systems Pharmacology. His research laboratory develops and implements methodologies to image tissues resected from cancer patients, extracting molecular information that sheds light on how cancers form and then develop their most aggressive features. With these tools, his group explores the tissue biology of cancer - the biological properties of cancer tissues, the molecular systems tumor cells use to evade immune surveillance, and the ways that cancer and immune cells assemble into dynamic ecosystems with emergent properties. This rich imaging data is being made available in the form of interactive tumor atlases as part of the National Cancer Institute’s Human Tumor Atlas Network (HTAN), a consortium which is assembling 2D and 3D maps of human precancers and cancers which can be browsed and analyzed by users in research and clinical practice to advance our understanding of cancer and to find new treatments.
webpage
Harvard Tissue Atlas
Mentoring
completed student projects
The Role of the Ciliogenesis Gene Program in Gliomas
Summer, 02/01/15 - 09/04/15
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
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U2CCA233262
(SORGER, PETER KARL)
Sep 30, 2018 - Jun 30, 2023
NIH
Pre-cancer atlases of cutaneous and hematologic origin (PATCH Center)
Role: Co-Principal Investigator
R01CA194005
(SANTAGATA, SANDRO)
Aug 11, 2016 - Jul 31, 2021
NIH
Investigating the HSF1 Cancer Network
Role: Principal Investigator
K08NS064168
(SANTAGATA, SANDRO)
Sep 1, 2008 - Oct 31, 2013
NIH
Heat Shock Directed Drug Discovery For The Treatment Of Gliomas
Role: Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Lin JR, Wang S,
Coy S
, Chen YA,
Yapp C
, Tyler M, Nariya MK, Heiser CN, Lau KS,
Santagata S
,
Sorger PK
. Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer. Cell. 2023 Jan 19; 186(2):363-381.e19.
PMID:
36669472
.
Citations:
Fields:
Cel
Cell Biology
Yapp C
, Novikov E, Jang WD,
Vallius T
, Chen YA, Cicconet M,
Maliga Z
, Jacobson CA, Wei D,
Santagata S
, Pfister H,
Sorger PK
. UnMICST: Deep learning with real augmentation for robust segmentation of highly multiplexed images of human tissues. Commun Biol. 2022 11 18; 5(1):1263.
PMID:
36400937
; PMCID:
PMC9674686
.
Citations:
Translation:
Humans
Animals
Cells
Lomakin A, Svedlund J, Strell C, Gataric M, Shmatko A, Rukhovich G, Park JS, Ju YS, Dentro S, Kleshchevnikov V, Vaskivskyi V, Li T, Bayraktar OA, Pinder S, Richardson AL,
Santagata S
, Campbell PJ, Russnes H, Gerstung M, Nilsson M, Yates LR. Spatial genomics maps the structure, nature and evolution of cancer clones. Nature. 2022 Nov; 611(7936):594-602.
PMID:
36352222
; PMCID:
PMC9668746
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Cells
Brastianos PK, Twohy EL,
Gerstner ER
, Kaufmann TJ,
Iafrate AJ
,
Lennerz J
, Jeyapalan S, Piccioni DE, Monga V, Fadul CE, Schiff D, Taylor JW, Chowdhary SA, Bettegowda C, Ansstas G, De La Fuente M, Anderson MD, Shonka N, Damek D, Carrillo J, Kunschner-Ronan LJ, Chaudhary R, Jaeckle KA, Senecal FM, Kaley T, Morrison T, Thomas AA, Welch MR, Iwamoto F, Cachia D, Cohen AL, Vora S, Knopp M, Dunn IF, Kumthekar P, Sarkaria J, Geyer S, Carrero XW, Martinez-Lage M,
Cahill DP
, Brown PD, Giannini C,
Santagata S
,
Barker FG
, Galanis E. Alliance A071401: Phase II Trial of Focal Adhesion Kinase Inhibition in Meningiomas With Somatic NF2 Mutations. J Clin Oncol. 2023 Jan 20; 41(3):618-628.
PMID:
36288512
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
CT
Clinical Trials
Choudhury A, Chen WC, Lucas CG, Bayley JC, Harmanci AS, Maas SLN,
Santagata S
, Klisch T, Perry A,
Bi WL
, Sahm F, Patel A, Magill ST, Raleigh DR. Hypermitotic meningiomas harbor DNA methylation subgroups with distinct biological and clinical features. Neuro Oncol. 2022 Oct 13.
PMID:
36227281
.
Citations:
Fields:
Neo
Neoplasms
Neu
Neurology
Muhlich JL
, Chen YA,
Yapp C
, Russell D,
Santagata S
,
Sorger PK
. Stitching and registering highly multiplexed whole-slide images of tissues and tumors using ASHLAR. Bioinformatics. 2022 09 30; 38(19):4613-4621.
PMID:
35972352
; PMCID:
PMC9525007
.
Citations:
5
Fields:
Com
Computational Biology
Translation:
Humans
Animals
Notarangelo G, Spinelli JB, Perez EM,
Baker GJ
,
Kurmi K
, Elia I,
Stopka SA
, Baquer G, Lin JR,
Golby AJ
, Joshi S, Baron HF,
Drijvers JM
,
Georgiev P
, Ringel AE, Zaganjor E, McBrayer SK,
Sorger PK
,
Sharpe AH
,
Wucherpfennig KW
,
Santagata S
, Agar NYR, Suvà ML,
Haigis MC
. Oncometabolite d-2HG alters T cell metabolism to impair CD8+ T cell function. Science. 2022 09 30; 377(6614):1519-1529.
PMID:
36173860
; PMCID:
PMC9629749
.
Citations:
1
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Warchol S, Krueger R,
Nirmal AJ
, Gaglia G, Jessup J, Ritch CC, Hoffer J,
Muhlich J
, Burger ML, Jacks T,
Santagata S
,
Sorger PK
, Pfister H. Visinity: Visual Spatial Neighborhood Analysis for Multiplexed Tissue Imaging Data. IEEE Trans Vis Comput Graph. 2022 Sep 28; PP.
PMID:
36170403
.
Citations:
Fields:
Med
Medical Informatics
Anderson AC
, Yanai I, Yates LR, Wang L, Swarbrick A,
Sorger P
,
Santagata S
, Fridman WH, Gao Q, Jerby L, Izar B, Shang L, Zhou X. Spatial transcriptomics. Cancer Cell. 2022 09 12; 40(9):895-900.
PMID:
36099884
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Woods JK
,
Lidov HG
,
Ligon KL
,
Santagata S
,
Chi SN
,
Yeo KK
,
Alexandrescu S
. PD-L1 and PD-1 expression in pediatric central nervous system germ cell tumors. Mod Pathol. 2022 12; 35(12):1770-1774.
PMID:
36057740
.
Citations:
Fields:
Pat
Pathology
Translation:
Humans
Coy S
, Wang S,
Stopka SA
, Lin JR,
Yapp C
, Ritch CC, Salhi L,
Baker GJ
, Rashid R, Baquer G, Regan M, Khadka P, Cole KA, Hwang J,
Wen PY
,
Bandopadhayay P
, Santi M, De Raedt T,
Ligon KL
, Agar NYR,
Sorger PK
,
Touat M
,
Santagata S
. Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma. Nat Commun. 2022 08 16; 13(1):4814.
PMID:
35973991
; PMCID:
PMC9381513
.
Citations:
2
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Lim-Fat MJ,
Youssef GC
,
Touat M
,
Iorgulescu JB
, Whorral S, Allen M,
Rahman R
,
Chukwueke U
, McFaline-Figueroa JR,
Nayak L
, Lee EQ,
Batchelor TT
,
Arnaout O
,
Peruzzi PP
,
Chiocca EA
,
Reardon DA
,
Meredith D
,
Santagata S
,
Beroukhim R
,
Bi WL
,
Ligon KL
,
Wen PY
. Clinical utility of targeted next-generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making. Neuro Oncol. 2022 07 01; 24(7):1140-1149.
PMID:
34878541
; PMCID:
PMC9248387
.
Citations:
4
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Nirmal AJ
,
Maliga Z
,
Vallius T
, Quattrochi B,
Chen AA
, Jacobson CA,
Pelletier RJ
,
Yapp C
, Arias-Camison R, Chen YA,
Lian CG
,
Murphy GF
,
Santagata S
,
Sorger PK
. The Spatial Landscape of Progression and Immunoediting in Primary Melanoma at Single-Cell Resolution. Cancer Discov. 2022 06 02; 12(6):1518-1541.
PMID:
35404441
; PMCID:
PMC9167783
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Gray GK,
Li CM
, Rosenbluth JM, Selfors LM,
Girnius N
, Lin JR, Schackmann RCJ, Goh WL, Moore K, Shapiro HK, Mei S, D'Andrea K, Nathanson KL,
Sorger PK
,
Santagata S
, Regev A,
Garber JE
,
Dillon DA
,
Brugge JS
. A human breast atlas integrating single-cell proteomics and transcriptomics. Dev Cell. 2022 06 06; 57(11):1400-1420.e7.
PMID:
35617956
; PMCID:
PMC9202341
.
Citations:
Fields:
Cel
Cell Biology
Emb
Embryology
Translation:
Humans
Animals
Cells
Driver J
, Hoffman SE, Tavakol S, Woodward E, Maury EA, Bhave V, Greenwald NF, Nassiri F, Aldape K, Zadeh G, Choudhury A, Vasudevan HN, Magill ST, Raleigh DR, Abedalthagafi M,
Aizer AA
, Alexander BM,
Ligon KL
,
Reardon DA
,
Wen PY
,
Al-Mefty O
,
Ligon AH
,
Dubuc AM
,
Beroukhim R
,
Claus EB
, Dunn IF,
Santagata S
, Linda Bi W. A molecularly integrated grade for meningioma. Neuro Oncol. 2022 05 04; 24(5):796-808.
PMID:
34508644
; PMCID:
PMC9071299
.
Citations:
7
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Tsvetkov P,
Coy S
,
Petrova B
, Dreishpoon M, Verma A, Abdusamad M, Rossen J, Joesch-Cohen L, Humeidi R, Spangler RD, Eaton JK, Frenkel E, Kocak M, Corsello SM, Lutsenko S,
Kanarek N
,
Santagata S
,
Golub TR
. Copper induces cell death by targeting lipoylated TCA cycle proteins. Science. 2022 03 18; 375(6586):1254-1261.
PMID:
35298263
; PMCID:
PMC9273333
.
Citations:
21
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Smith RS, Takagishi SR, Amici DR, Metz K, Gayatri S, Alasady MJ, Wu Y, Brockway S, Taiberg SL, Khalatyan N, Taipale M,
Santagata S
, Whitesell L, Lindquist S, Savas JN, Mendillo ML. HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state. Sci Adv. 2022 Mar 18; 8(11):eabj6526.
PMID:
35294249
; PMCID:
PMC8926329
.
Citations:
1
Fields:
Sci
Science
Gaglia G,
Kabraji S
, Rammos D, Dai Y, Verma A, Wang S,
Mills CE
, Chung M,
Bergholz JS
,
Coy S
, Lin JR,
Jeselsohn R
,
Metzger O
, Winer EP,
Dillon DA
,
Zhao JJ
,
Sorger PK
,
Santagata S
. Temporal and spatial topography of cell proliferation in cancer. Nat Cell Biol. 2022 03; 24(3):316-326.
PMID:
35292783
; PMCID:
PMC8959396
.
Citations:
Fields:
Cel
Cell Biology
Translation:
Humans
Brastianos PK, Kim AE, Giobbie-Hurder A,
Lee EQ
, Wang N,
Eichler AF
,
Chukwueke U
,
Forst DA
,
Arrillaga-Romany IC
,
Dietrich J
, Corbin Z, Moliterno J, Baehring J, White M, Lou KW, Larson J, de Sauvage MA, Evancic K, Mora J, Nayyar N,
Loeffler J
, Oh K,
Shih HA
,
Curry WT
,
Cahill DP
,
Barker FG
,
Gerstner ER
,
Santagata S
. Phase 2 study of pembrolizumab in patients with recurrent and residual high-grade meningiomas. Nat Commun. 2022 03 14; 13(1):1325.
PMID:
35289329
; PMCID:
PMC8921328
.
Citations:
3
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
CT
Clinical Trials
Schapiro D,
Yapp C
, Sokolov A, Reynolds SM, Chen YA, Sudar D, Xie Y,
Muhlich J
, Arias-Camison R, Arena S, Taylor AJ, Nikolov M, Tyler M, Lin JR, Burlingame EA, Chang YH, Farhi SL, Thorsson V, Venkatamohan N, Drewes JL, Pe'er D, Gutman DA, Herrmann MD,
Gehlenborg N
, Bankhead P, Roland JT, Herndon JM, Snyder MP, Angelo M, Nolan G, Swedlow JR, Schultz N, Merrick DT, Mazzili SA,
Cerami E
,
Rodig SJ
,
Santagata S
,
Sorger PK
. MITI minimum information guidelines for highly multiplexed tissue images. Nat Methods. 2022 03; 19(3):262-267.
PMID:
35277708
; PMCID:
PMC9009186
.
Citations:
6
Fields:
Cli
Clinical Laboratory Techniques
Launonen IM, Lyytikäinen N, Casado J, Anttila EA, Szabó A, Haltia UM, Jacobson CA, Lin JR,
Maliga Z
, Howitt BE, Strickland KC,
Santagata S
,
Elias K
,
D'Andrea AD
,
Konstantinopoulos PA
,
Sorger PK
, Färkkilä A. Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer. Nat Commun. 2022 02 11; 13(1):835.
PMID:
35149709
; PMCID:
PMC8837628
.
Citations:
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Bi WL
,
Nayak L
,
Meredith DM
,
Driver J
, Du Z, Hoffman S, Li Y,
Lee EQ
,
Beroukhim R
,
Rinne M
, McFaline-Figueroa R,
Chukwueke U
, McCluskey C, Gaffey S,
Cherniack AD
, Stefanik J, Doherty L, Taubert C, Cifrino M, LaFrankie D, Graillon T,
Wen PY
,
Ligon KL
,
Al-Mefty O
,
Huang RY
, Muzikansky A,
Chiocca EA
,
Santagata S
, Dunn IF,
Reardon DA
. Activity of PD-1 blockade with nivolumab among patients with recurrent atypical/anaplastic meningioma: phase II trial results. Neuro Oncol. 2022 01 05; 24(1):101-113.
PMID:
34015129
; PMCID:
PMC8730772
.
Citations:
7
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
CT
Clinical Trials
Lopez BGC, Kohale IN, Du Z,
Korsunsky I
, Abdelmoula WM, Dai Y,
Stopka SA
, Gaglia G, Randall EC, Regan MS, Basu SS, Clark AR, Marin BM, Mladek AC, Burgenske DM, Agar JN,
Supko JG
, Grossman SA, Nabors LB,
Raychaudhuri S
,
Ligon KL
,
Wen PY
, Alexander B,
Lee EQ
,
Santagata S
, Sarkaria J, White FM, Agar NYR. Multimodal platform for assessing drug distribution and response in clinical trials. Neuro Oncol. 2022 01 05; 24(1):64-77.
PMID:
34383057
; PMCID:
PMC8730776
.
Citations:
1
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Jessup J, Krueger R, Warchol S, Hoffer J,
Muhlich J
, Ritch CC, Gaglia G,
Coy S
, Chen YA, Lin JR,
Santagata S
,
Sorger PK
, Pfister H. Scope2Screen: Focus+Context Techniques for Pathology Tumor Assessment in Multivariate Image Data. IEEE Trans Vis Comput Graph. 2022 01; 28(1):259-269.
PMID:
34606456
; PMCID:
PMC8805697
.
Citations:
1
Fields:
Med
Medical Informatics
Translation:
Humans
Schapiro D, Sokolov A,
Yapp C
, Chen YA,
Muhlich JL
, Hess J, Creason AL,
Nirmal AJ
,
Baker GJ
, Nariya MK, Lin JR,
Maliga Z
, Jacobson CA, Hodgman MW, Ruokonen J, Farhi SL, Abbondanza D, McKinley ET, Persson D, Betts C, Sivagnanam S, Regev A, Goecks J, Coffey RJ, Coussens LM,
Santagata S
,
Sorger PK
. MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging. Nat Methods. 2022 03; 19(3):311-315.
PMID:
34824477
; PMCID:
PMC8916956
.
Citations:
11
Fields:
Cli
Clinical Laboratory Techniques
Translation:
Humans
Bi WL
,
Santagata S
. Skull Base Tumors: Neuropathology and Clinical Implications. Neurosurgery. 2022 03 01; 90(3):243-261.
PMID:
34164689
.
Citations:
Fields:
Neu
Neurosurgery
Translation:
Humans
Rashid R, Chen YA,
Hoffer J
,
Muhlich JL
, Lin JR, Krueger R, Pfister H,
Mitchell R
,
Santagata S
,
Sorger PK
. Narrative online guides for the interpretation of digital-pathology images and tissue-atlas data. Nat Biomed Eng. 2022 05; 6(5):515-526.
PMID:
34750536
; PMCID:
PMC9079188
.
Citations:
3
Fields:
Bio
Biomedical Engineering
Burger ML, Cruz AM, Crossland GE, Gaglia G, Ritch CC, Blatt SE, Bhutkar A, Canner D, Kienka T, Tavana SZ, Barandiaran AL, Garmilla A,
Schenkel JM
, Hillman M, de Los Rios Kobara I, Li A, Jaeger AM,
Hwang WL
, Westcott PMK, Manos MP, Holovatska MM,
Hodi FS
, Regev A,
Santagata S
, Jacks T. Antigen dominance hierarchies shape TCF1+ progenitor CD8 TÂ cell phenotypes in tumors. Cell. 2021 09 16; 184(19):4996-5014.e26.
PMID:
34534464
; PMCID:
PMC8522630
.
Citations:
9
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
PH
Public Health
Basu SS,
Stopka SA
, Abdelmoula WM, Randall EC, Gimenez-Cassina Lopez B, Regan MS, Calligaris D, Lu FF, Norton I, Mallory MA,
Santagata S
,
Dillon DA
, Golshan M, Agar NYR. Interim clinical trial analysis of intraoperative mass spectrometry for breast cancer surgery. NPJ Breast Cancer. 2021 Sep 09; 7(1):116.
PMID:
34504095
.
Citations:
Koikawa K, Kibe S, Suizu F, Sekino N, Kim N, Manz TD, Pinch BJ, Akshinthala D, Verma A, Gaglia G, Nezu Y,
Ke S
,
Qiu C
, Ohuchida K, Oda Y, Lee TH,
Wegiel B
,
Clohessy JG
, London N,
Santagata S
,
Wulf GM
, Hidalgo M, Muthuswamy SK, Nakamura M, Gray NS, Zhou XZ, Lu KP. Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy. Cell. 2021 09 02; 184(18):4753-4771.e27.
PMID:
34388391
; PMCID:
PMC8557351
.
Citations:
14
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Santagata S
,
Ligon KL
. Prognostication for meningiomas: H3K27me3 to the rescue? Neuro Oncol. 2021 08 02; 23(8):1218-1219.
PMID:
33822195
; PMCID:
PMC8328006
.
Citations:
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Brastianos PK, Kim AE, Wang N,
Lee EQ
,
Ligibel J
, Cohen JV,
Chukwueke UN
, Mahar M, Oh K, White MD,
Shih HA
,
Forst D
,
Gainor JF
,
Heist RS
,
Gerstner ER
,
Batchelor TT
, Lawrence D,
Ryan DP
,
Iafrate AJ
, Giobbie-Hurder A,
Santagata S
,
Carter SL
,
Cahill DP
, Sullivan RJ. Palbociclib demonstrates intracranial activity in progressive brain metastases harboring cyclin-dependent kinase pathway alterations. Nat Cancer. 2021 05; 2(5):498-502.
PMID:
35122016
.
Citations:
5
Translation:
Humans
Iida K, Abdelhamid Ahmed AH, Nagatsuma AK, Shibutani T, Yasuda S, Kitamura M, Hattori C, Abe M, Hasegawa J, Iguchi T, Karibe T, Nakada T, Inaki K, Kamei R, Abe Y, Nomura T, Andersen JL,
Santagata S
, Hemming ML,
George S
, Doi T, Ochiai A,
Demetri GD
, Agatsuma T. Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody-Drug Conjugate. Cancer Discov. 2021 06; 11(6):1508-1523.
PMID:
33579785
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
CT
Clinical Trials
Hemming ML,
Coy S
, Lin JR, Andersen JL, Przybyl J,
Mazzola E
, Abdelhamid Ahmed AH, van de Rijn M,
Sorger PK
,
Armstrong SA
,
Demetri GD
,
Santagata S
. HAND1 and BARX1 Act as Transcriptional and Anatomic Determinants of Malignancy in Gastrointestinal Stromal Tumor. Clin Cancer Res. 2021 03 15; 27(6):1706-1719.
PMID:
33451979
; PMCID:
PMC7956056
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Juratli TA, Prilop I, Saalfeld FC, Herold S, Meinhardt M, Wenzel C, Zeugner S, Aust DE,
Barker FG
,
Cahill DP
, Brastianos PK,
Santagata S
, Schackert G, Pinzer T. Sporadic multiple meningiomas harbor distinct driver mutations. Acta Neuropathol Commun. 2021 01 06; 9(1):8.
PMID:
33407897
.
Citations:
3
Fields:
Neu
Neurology
Translation:
Humans
Mehta AK
, Cheney EM, Hartl CA, Pantelidou C, Oliwa M, Castrillon JA, Lin JR, Hurst KE, de Oliveira Taveira M, Johnson NT,
Oldham WM
, Kalocsay M, Berberich MJ, Boswell SA, Kothari A, Johnson S,
Dillon DA
, Lipschitz M,
Rodig S
,
Santagata S
,
Garber JE
,
Tung N
, Yélamos J, Thaxton JE,
Mittendorf EA
,
Sorger PK
,
Shapiro GI
,
Guerriero JL
. Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer. Nat Cancer. 2021 01; 2(1):66-82.
PMID:
33738458
; PMCID:
PMC7963404
.
Citations:
33
Translation:
Humans
Cells
Williams EA,
Santagata S
,
Wakimoto H
, Shankar GM,
Barker FG
, Sharaf R, Reddy A, Spear P, Alexander BM, Ross JS, Brastianos PK,
Cahill DP
, Ramkissoon SH, Juratli TA. Distinct genomic subclasses of high-grade/progressive meningiomas: NF2-associated, NF2-exclusive, and NF2-agnostic. Acta Neuropathol Commun. 2020 10 21; 8(1):171.
PMID:
33087175
.
Citations:
14
Fields:
Neu
Neurology
Translation:
Humans
Cells
Hoffer J
, Rashid R,
Muhlich JL
, Chen YA, Russell DPW, Ruokonen J, Krueger R, Pfister H,
Santagata S
,
Sorger PK
. Minerva: a light-weight, narrative image browser for multiplexed tissue images. J Open Source Softw. 2020; 5(54).
PMID:
33768192
.
Citations:
5
Baker GJ
,
Muhlich JL
, Palaniappan SK, Moore JK, Davis SH,
Santagata S
,
Sorger PK
. SYLARAS: A Platform for the Statistical Analysis and Visual Display of Systemic Immunoprofiling Data and Its Application to Glioblastoma. Cell Syst. 2020 09 23; 11(3):272-285.e9.
PMID:
32898474
.
Citations:
3
Fields:
Cel
Cell Biology
Com
Computational Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Färkkilä A,
Gulhan DC
, Casado J, Jacobson CA, Nguyen H, Kochupurakkal B,
Maliga Z
,
Yapp C
, Chen YA, Schapiro D, Zhou Y, Graham JR, Dezube BJ, Munster P,
Santagata S
, Garcia E,
Rodig S
, Lako A,
Chowdhury D
,
Shapiro GI
,
Matulonis UA
,
Park PJ
, Hautaniemi S,
Sorger PK
, Swisher EM,
D'Andrea AD
,
Konstantinopoulos PA
. Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer. Nat Commun. 2020 05 18; 11(1):2543.
PMID:
32424117
.
Citations:
3
Fields:
Bio
Biology
Sci
Science
Williams EA,
Wakimoto H
, Shankar GM,
Barker FG
, Brastianos PK,
Santagata S
, Sokol ES, Pavlick DC, Shah N, Reddy A, Venstrom JM, Alexander BM, Ross JS,
Cahill DP
, Ramkissoon SH, Juratli TA. Frequent inactivating mutations of the PBAF complex gene PBRM1 in meningioma with papillary features. Acta Neuropathol. 2020 07; 140(1):89-93.
PMID:
32405805
.
Citations:
7
Fields:
Neu
Neurology
Translation:
Humans
Rozenblatt-Rosen O, Regev A, Oberdoerffer P, Nawy T, Hupalowska A, Rood JE, Ashenberg O,
Cerami E
, Coffey RJ, Demir E, Ding L, Esplin ED, Ford JM, Goecks J, Ghosh S, Gray JW, Guinney J, Hanlon SE, Hughes SK, Hwang ES, Iacobuzio-Donahue CA, Jané-Valbuena J,
Johnson BE
, Lau KS, Lively T, Mazzilli SA, Pe'er D,
Santagata S
,
Shalek AK
, Schapiro D, Snyder MP,
Sorger PK
, Spira AE, Srivastava S, Tan K, West RB, Williams EH. The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution. Cell. 2020 04 16; 181(2):236-249.
PMID:
32302568
; PMCID:
PMC7376497
.
Citations:
96
Fields:
Cel
Cell Biology
Translation:
Humans
Touat M
,
Li YY
, Boynton AN, Spurr LF,
Iorgulescu JB
,
Bohrson CL
, Cortes-Ciriano I, Birzu C, Geduldig JE, Pelton K, Lim-Fat MJ,
Pal S
, Ferrer-Luna R, Ramkissoon SH, Dubois F, Bellamy C, Currimjee N, Bonardi J, Qian K, Ho P, Malinowski S, Taquet L, Jones RE, Shetty A, Chow KH, Sharaf R, Pavlick D, Albacker LA, Younan N, Baldini C, Verreault M, Giry M, Guillerm E, Ammari S, Beuvon F, Mokhtari K, Alentorn A, Dehais C, Houillier C, Laigle-Donadey F, Psimaras D,
Lee EQ
,
Nayak L
, McFaline-Figueroa JR, Carpentier A, Cornu P, Capelle L, Mathon B, Barnholtz-Sloan JS, Chakravarti A,
Bi WL
,
Chiocca EA
,
Fehnel KP
,
Alexandrescu S
,
Chi SN
,
Haas-Kogan D
,
Batchelor TT
, Frampton GM, Alexander BM,
Huang RY
,
Ligon AH
, Coulet F, Delattre JY, Hoang-Xuan K,
Meredith DM
,
Santagata S
, Duval A, Sanson M,
Cherniack AD
,
Wen PY
,
Reardon DA
, Marabelle A,
Park PJ
, Idbaih A,
Beroukhim R
,
Bandopadhayay P
, Bielle F,
Ligon KL
. Mechanisms and therapeutic implications of hypermutation in gliomas. Nature. 2020 04; 580(7804):517-523.
PMID:
32322066
; PMCID:
PMC8235024
.
Citations:
130
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Guerra SL, Maertens O, Kuzmickas R, De Raedt T,
Adeyemi RO
, Guild CJ, Guillemette S, Redig AJ, Chambers ES, Xu M, Tiv H,
Santagata S
, Jänne PA,
Elledge SJ
,
Cichowski K
. A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers. Cancer Cell. 2020 05 11; 37(5):705-719.e6.
PMID:
32243838
.
Citations:
17
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Coy S
, Rashid R,
Stemmer-Rachamimov A
,
Santagata S
. Correction to: An update on the CNS manifestations of neurofibromatosis type 2. Acta Neuropathol. 2020 Apr; 139(4):667.
PMID:
31432207
; PMCID:
PMC7096359
.
Citations:
Fields:
Neu
Neurology
Shih DJH, Nayyar N, Bihun I,
Dagogo-Jack I
, Gill CM,
Aquilanti E
, Bertalan M, Kaplan A, D'Andrea MR,
Chukwueke U
, Ippen FM, Alvarez-Breckenridge C, Camarda ND, Lastrapes M, McCabe D, Kuter B, Kaufman B,
Strickland MR
, Martinez-Gutierrez JC, Nagabhushan D, De Sauvage M, White MD, Castro BA, Hoang K, Kaneb A, Batchelor ED, Paek SH, Park SH, Martinez-Lage M, Berghoff AS,
Merrill P
,
Gerstner ER
,
Batchelor TT
,
Frosch MP
, Frazier RP, Borger DR,
Iafrate AJ
,
Johnson BE
,
Santagata S
, Preusser M,
Cahill DP
,
Carter SL
, Brastianos PK. Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma. Nat Genet. 2020 04; 52(4):371-377.
PMID:
32203465
; PMCID:
PMC7136154
.
Citations:
55
Fields:
Gen
Genetics
Translation:
Humans
Animals
Cells
Färkkilä A,
Gulhan DC
, Casado J, Jacobson CA, Nguyen H, Kochupurakkal B,
Maliga Z
,
Yapp C
, Chen YA, Schapiro D, Zhou Y, Graham JR, Dezube BJ, Munster P,
Santagata S
, Garcia E,
Rodig S
, Lako A,
Chowdhury D
,
Shapiro GI
,
Matulonis UA
,
Park PJ
, Hautaniemi S,
Sorger PK
, Swisher EM,
D'Andrea AD
,
Konstantinopoulos PA
. Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer. Nat Commun. 2020 03 19; 11(1):1459.
PMID:
32193378
.
Citations:
69
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
CT
Clinical Trials
Heaphy CM,
Bi WL
,
Coy S
, Davis C, Gallia GL,
Santagata S
, Rodriguez FJ. Telomere length alterations and ATRX/DAXX loss in pituitary adenomas. Mod Pathol. 2020 08; 33(8):1475-1481.
PMID:
32203094
; PMCID:
PMC8867890
.
Citations:
3
Fields:
Pat
Pathology
Translation:
Humans
Cells
Hemming ML, Nathenson MJ, Lin JR, Mei S, Du Z, Malik K, Marino-Enriquez A, Jagannathan JP,
Sorger PK
, Bertagnolli M,
Sicinska E
,
Demetri GD
,
Santagata S
. Response and mechanisms of resistance to larotrectinib and selitrectinib in metastatic undifferentiated sarcoma harboring oncogenic fusion of NTRK1. JCO Precis Oncol. 2020; 4:79-90.
PMID:
32133433
; PMCID:
PMC7055910
.
Citations:
6
Fields:
Neo
Neoplasms
Gaglia G, Rashid R,
Yapp C
, Joshi GN, Li CG, Lindquist SL,
Sarosiek KA
, Whitesell L,
Sorger PK
,
Santagata S
. HSF1 phase transition mediates stress adaptation and cell fate decisions. Nat Cell Biol. 2020 02; 22(2):151-158.
PMID:
32015439
.
Citations:
26
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Rashid R, Gaglia G, Chen YA, Lin JR, Du Z,
Maliga Z
, Schapiro D,
Yapp C
,
Muhlich J
, Sokolov A,
Sorger P
,
Santagata S
. Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer. Sci Data. 2019 12 17; 6(1):323.
PMID:
31848351
.
Citations:
18
Fields:
Sci
Science
Translation:
Humans
Randall EC, Lopez BGC, Peng S, Regan MS, Abdelmoula WM, Basu SS,
Santagata S
, Yoon H,
Haigis MC
, Agar JN, Tran NL, Elmquist WF, White FM, Sarkaria JN, Agar NYR. Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma. Cancer Res. 2020 03 15; 80(6):1258-1267.
PMID:
31767628
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Du Z, Lin JR, Rashid R,
Maliga Z
, Wang S, Aster JC, Izar B,
Sorger PK
,
Santagata S
. Qualifying antibodies for image-based immune profiling and multiplexed tissue imaging. Nat Protoc. 2019 10; 14(10):2900-2930.
PMID:
31534232
; PMCID:
PMC6959005
.
Citations:
27
Fields:
Cli
Clinical Laboratory Techniques
Sci
Science
Translation:
Humans
Animals
Freedman RA
,
Gelman RS
, Agar NYR,
Santagata S
, Randall EC, Gimenez-Cassina Lopez B, Connolly RM, Dunn IF, Van Poznak CH, Anders CK, Melisko ME, Silvestri K, Cotter CM, Componeschi KP, Marte JM,
Moy B
, Blackwell KL, Puhalla SL, Ibrahim N, Moynihan TJ, Nangia J,
Tung N
, Burns R, Rimawi MF, Krop IE, Wolff AC,
Winer EP
,
Lin NU
. Pre- and Postoperative Neratinib for HER2-Positive Breast Cancer Brain Metastases: Translational Breast Cancer Research Consortium 022. Clin Breast Cancer. 2020 04; 20(2):145-151.e2.
PMID:
31558424
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Juratli TA,
Jones PS
, Wang N, Subramanian M, Aylwin SJB, Odia Y, Rostami E, Gudjonsson O, Shaw BL,
Cahill DP
, Galanis E,
Barker FG
,
Santagata S
, Brastianos PK. Targeted treatment of papillary craniopharyngiomas harboring BRAF V600E mutations. Cancer. 2019 09 01; 125(17):2910-2914.
PMID:
31314136
; PMCID:
PMC7032527
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Basu SS, Regan MS, Randall EC, Abdelmoula WM,
Clark AR
, Gimenez-Cassina Lopez B, Cornett DS, Haase A,
Santagata S
, Agar NYR. Rapid MALDI mass spectrometry imaging for surgical pathology. NPJ Precis Oncol. 2019; 3:17.
PMID:
31286061
; PMCID:
PMC6609678
.
Citations:
18
Tsvetkov P, Detappe A, Cai K, Keys HR, Brune Z, Ying W, Thiru P, Reidy M, Kugener G, Rossen J, Kocak M,
Kory N
, Tsherniak A,
Santagata S
, Whitesell L,
Ghobrial IM
, Markley JL, Lindquist S,
Golub TR
. Author Correction: Mitochondrial metabolism promotes adaptation to proteotoxic stress. Nat Chem Biol. 2019 Jul; 15(7):757.
PMID:
31164776
; PMCID:
PMC8189136
.
Citations:
1
Fields:
Bio
Biology
Che
Chemistry
Jaeger AM, Stopfer L, Lee S, Gaglia G, Sandel D,
Santagata S
,
Lin NU
, Trepel JB, White F, Jacks T, Lindquist S, Whitesell L. Rebalancing Protein Homeostasis Enhances Tumor Antigen Presentation. Clin Cancer Res. 2019 11 01; 25(21):6392-6405.
PMID:
31213460
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Coy S
, Rashid R,
Stemmer-Rachamimov A
,
Santagata S
. An update on the CNS manifestations of neurofibromatosis type 2. Acta Neuropathol. 2020 04; 139(4):643-665.
PMID:
31161239
.
Citations:
21
Fields:
Neu
Neurology
Translation:
Humans
Bandopadhayay P
, Piccioni F, O'Rourke R, Ho P, Gonzalez EM, Buchan G, Qian K, Gionet G, Girard E, Coxon M, Rees MG, Brenan L, Dubois F, Shapira O, Greenwald NF,
Pages M
, Balboni Iniguez A, Paolella BR, Meng A, Sinai C, Roti G, Dharia NV, Creech A, Tanenbaum B, Khadka P, Tracy A, Tiv HL, Hong AL,
Coy S
, Rashid R, Lin JR, Cowley GS, Lam FC, Goodale A, Lee Y, Schoolcraft K, Vazquez F,
Hahn WC
, Tsherniak A, Bradner JE,
Yaffe MB
, Milde T, Pfister SM, Qi J, Schenone M, Carr SA,
Ligon KL
, Kieran MW,
Santagata S
, Olson JM, Gokhale PC, Jaffe JD, Root DE,
Stegmaier K
, Johannessen CM,
Beroukhim R
. Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma. Nat Commun. 2019 06 03; 10(1):2400.
PMID:
31160565
.
Citations:
16
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Cells
Tsvetkov P, Detappe A, Cai K, Keys HR, Brune Z, Ying W, Thiru P, Reidy M, Kugener G, Rossen J, Kocak M,
Kory N
, Tsherniak A,
Santagata S
, Whitesell L,
Ghobrial IM
, Markley JL, Lindquist S,
Golub TR
. Mitochondrial metabolism promotes adaptation to proteotoxic stress. Nat Chem Biol. 2019 07; 15(7):681-689.
PMID:
31133756
.
Citations:
37
Fields:
Bio
Biology
Che
Chemistry
Translation:
Humans
Animals
Cells
Alexander BM,
Trippa L
, Gaffey S,
Arrillaga-Romany IC
,
Lee EQ
,
Rinne ML
, Ahluwalia MS, Colman H, Fell G, Galanis E, de Groot J, Drappatz J, Lassman AB,
Meredith DM
, Nabors LB,
Santagata S
, Schiff D, Welch MR,
Ligon KL
,
Wen PY
. Individualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT): A Bayesian Adaptive Platform Trial to Develop Precision Medicines for Patients With Glioblastoma. JCO Precis Oncol. 2019; 3.
PMID:
32914038
; PMCID:
PMC7448806
.
Citations:
19
Fields:
Neo
Neoplasms
Fritchie K, Jensch K, Moskalev EA, Caron A, Jenkins S, Link M, Brown PD, Rodriguez FJ, Guajardo A, Brat D, Velázquez Vega JE, Perry A, Wu A, Raleigh DR,
Santagata S
,
Louis DN
, Brastianos PK, Kaplan A, Alexander BM, Rossi S, Ferrarese F, Haller F, Giannini C. The impact of histopathology and NAB2-STAT6 fusion subtype in classification and grading of meningeal solitary fibrous tumor/hemangiopericytoma. Acta Neuropathol. 2019 02; 137(2):307-319.
PMID:
30584643
; PMCID:
PMC6513906
.
Citations:
16
Fields:
Neu
Neurology
Translation:
Humans
Walpole S, Pritchard AL, Cebulla CM, Pilarski R, Stautberg M, Davidorf FH, de la Fouchardière A, Cabaret O, Golmard L, Stoppa-Lyonnet D, Garfield E, Njauw CN, Cheung M, Turunen JA, Repo P, Järvinen RS, van Doorn R, Jager MJ, Luyten GPM, Marinkovic M, Chau C, Potrony M, Höiom V, Helgadottir H, Pastorino L, Bruno W, Andreotti V, Dalmasso B, Ciccarese G, Queirolo P, Mastracci L, Wadt K, Kiilgaard JF, Speicher MR, van Poppelen N, Kilic E, Al-Jamal RT, Dianzani I, Betti M, Bergmann C,
Santagata S
, Dahiya S, Taibjee S, Burke J, Poplawski N, O'Shea SJ, Newton-Bishop J, Adlard J, Adams DJ,
Lane AM
, Kim I, Klebe S, Racher H, Harbour JW, Nickerson ML, Murali R, Palmer JM, Howlie M, Symmons J, Hamilton H, Warrier S, Glasson W, Johansson P, Robles-Espinoza CD, Ossio R, de Klein A, Puig S, Ghiorzo P, Nielsen M, Kivelä TT,
Tsao H
, Testa JR, Gerami P, Stern MH, Paillerets BB, Abdel-Rahman MH, Hayward NK. Comprehensive Study of the Clinical Phenotype of Germline BAP1 Variant-Carrying Families Worldwide. J Natl Cancer Inst. 2018 12 01; 110(12):1328-1341.
PMID:
30517737
.
Citations:
59
Fields:
Neo
Neoplasms
Translation:
Humans
Venur VA,
Santagata S
, Galanis E, Brastianos PK. New molecular targets in meningiomas: the present and the future. Curr Opin Neurol. 2018 12; 31(6):740-746.
PMID:
30379704
.
Citations:
7
Fields:
Neu
Neurology
Translation:
Humans
Animals
Dunn IF, Du Z,
Touat M
, Sisti MB,
Wen PY
,
Umeton R
,
Dubuc AM
, Ducar M, Canoll PD, Severson E, Elvin JA, Ramkissoon SH, Lin JR, Cabrera L, Acevedo B,
Sorger PK
,
Ligon KL
,
Santagata S
,
Reardon DA
. Mismatch repair deficiency in high-grade meningioma: a rare but recurrent event associated with dramatic immune activation and clinical response to PD-1 blockade. JCO Precis Oncol. 2018; 2018.
PMID:
30801050
; PMCID:
PMC6383717
.
Citations:
18
Fields:
Neo
Neoplasms
Aquilanti E
, Miller J,
Santagata S
,
Cahill DP
, Brastianos PK. Updates in prognostic markers for gliomas. Neuro Oncol. 2018 11 09; 20(suppl_7):vii17-vii26.
PMID:
30412261
; PMCID:
PMC6225747
.
Citations:
39
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Cells
Torre M
,
Solomon IH
, Sutherland CL,
Nikiforow S
,
DeAngelo DJ
,
Stone RM
, Vaitkevicius H, Galinsky IA,
Padera RF
, Trede N,
Santagata S
. Neuropathology of a Case With Fatal CAR T-Cell-Associated Cerebral Edema. J Neuropathol Exp Neurol. 2018 10 01; 77(10):877-882.
PMID:
30060228
.
Citations:
23
Fields:
Neu
Neurology
Pat
Pathology
Translation:
Humans
Cells
Du Z,
Brewster R
,
Merrill PH
, Chmielecki J, Francis J,
Aizer A
, Abedalthagafi M,
Sholl LM
, Geffers L, Alexander B,
Santagata S
. Meningioma transcription factors link cell lineage with systemic metabolic cues. Neuro Oncol. 2018 09 03; 20(10):1331-1343.
PMID:
29660031
.
Citations:
3
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Animals
Cells
Clark AR
, Calligaris D, Regan MS, Pomeranz Krummel D, Agar JN, Kallay L, MacDonald T, Schniederjan M,
Santagata S
,
Pomeroy SL
, Agar NYR, Sengupta S. Rapid discrimination of pediatric brain tumors by mass spectrometry imaging. J Neurooncol. 2018 Nov; 140(2):269-279.
PMID:
30128689
; PMCID:
PMC6244779
.
Citations:
18
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Juratli TA, McCabe D, Nayyar N, Williams EA, Silverman IM, Tummala SS, Fink AL, Baig A, Martinez-Lage M, Selig MK, Bihun IV,
Shankar GM
, Penson T, Lastrapes M, Daubner D, Meinhardt M, Hennig S, Kaplan AB, Fujio S, Kuter BM, Bertalan MS,
Miller JJ
, Batten JM, Ely HA, Christiansen J, Baretton GB,
Stemmer-Rachamimov AO
,
Santagata S
,
Rivera MN
,
Barker FG
, Schackert G,
Wakimoto H
,
Iafrate AJ
,
Carter SL
,
Cahill DP
,
Brastianos PK
. DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome. Acta Neuropathol. 2018 11; 136(5):779-792.
PMID:
30123936
.
Citations:
28
Fields:
Neu
Neurology
Translation:
Humans
Cells
Lin JR, Izar B, Wang S,
Yapp C
, Mei S, Shah PM,
Santagata S
,
Sorger PK
. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. Elife. 2018 07 11; 7.
PMID:
29993362
; PMCID:
PMC6075866
.
Citations:
154
Fields:
Bio
Biology
Translation:
Humans
Cells
Coy S
, Rashid R, Lin JR, Du Z, Donson AM, Hankinson TC, Foreman NK, Manley PE, Kieran MW,
Reardon DA
,
Sorger PK
,
Santagata S
. Multiplexed immunofluorescence reveals potential PD-1/PD-L1 pathway vulnerabilities in craniopharyngioma. Neuro Oncol. 2018 07 05; 20(8):1101-1112.
PMID:
29509940
; PMCID:
PMC6280314
.
Citations:
19
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Cells
Galanis E, Nassiri F,
Coy S
, Nejad R, Zadeh G,
Santagata S
. Integrating Genomics Into Neuro-Oncology Clinical Trials and Practice. Am Soc Clin Oncol Educ Book. 2018 May 23; 38:148-157.
PMID:
30231374
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Du Z,
Santagata S
. Uncovering the links between systemic hormones and oncogenic signaling in the pathogenesis of meningioma. Ann Oncol. 2018 03 01; 29(3):537-540.
PMID:
29346520
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Mobark NA, Al-Harbi M, Mosleh O,
Santagata S
, Snuderl M, Abedalthagafi M. A case of molecularly profiled extraneural medulloblastoma metastases in a child. BMC Med Genet. 2018 01 17; 19(1):10.
PMID:
29343221
; PMCID:
PMC5772742
.
Citations:
Fields:
Gen
Genetics
Translation:
Humans
Rasool N,
Lefebvre DR
,
Latina MA
, Dunn IF,
Santagata S
,
Freitag SK
,
Cestari DM
. Orbital leiomyosarcoma metastasis presenting prior to diagnosis of the primary tumor. Digit J Ophthalmol. 2017; 23(4):22-26.
PMID:
29403338
.
Citations:
Fields:
Oph
Ophthalmology
Translation:
Humans
Coroller TP,
Bi WL
, Huynh E, Abedalthagafi M,
Aizer AA
, Greenwald NF, Parmar C, Narayan V, Wu WW, Miranda de Moura S,
Gupta S
,
Beroukhim R
,
Wen PY
,
Al-Mefty O
, Dunn IF,
Santagata S
,
Alexander BM
,
Huang RY
,
Aerts HJWL
. Radiographic prediction of meningioma grade by semantic and radiomic features. PLoS One. 2017; 12(11):e0187908.
PMID:
29145421
.
Citations:
36
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Shankar GM
,
Santagata S
. BAP1 mutations in high-grade meningioma: implications for patient care. Neuro Oncol. 2017 Oct 19; 19(11):1447-1456.
PMID:
28482042
; PMCID:
PMC5737364
.
Citations:
26
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Coy S
,
Dubuc AM
, Dahiya S,
Ligon KL
, Vasiljevic A,
Santagata S
. Nuclear CRX and FOXJ1 Expression Differentiates Non-Germ Cell Pineal Region Tumors and Supports the Ependymal Differentiation of Papillary Tumor of the Pineal Region. Am J Surg Pathol. 2017 Oct; 41(10):1410-1421.
PMID:
28719464
.
Citations:
2
Fields:
Gen
General Surgery
Pat
Pathology
Translation:
Humans
Cells
Mei Y
, Du Z, Hu C, Greenwald NF, Abedalthagafi M, Agar NYR,
Dunn GP
,
Bi WL
,
Santagata S
, Dunn IF. Osteoglycin promotes meningioma development through downregulation of NF2 and activation of mTOR signaling. Cell Commun Signal. 2017 09 18; 15(1):34.
PMID:
28923059
; PMCID:
PMC5604305
.
Citations:
9
Fields:
Bio
Biochemistry
Cel
Cell Biology
Translation:
Humans
Cells
Bi WL
, Greenwald NF, Abedalthagafi M, Wala J, Gibson WJ, Agarwalla PK, Horowitz P, Schumacher SE, Esaulova E, Mei Y, Chevalier A, A Ducar M, Thorner AR, van Hummelen P, O Stemmer-Rachamimov A, Artyomov M,
Al-Mefty O
,
Dunn GP
,
Santagata S
, Dunn IF,
Beroukhim R
. Erratum: Genomic landscape of high-grade meningiomas. NPJ Genom Med. 2017; 2:26.
PMID:
29263836
; PMCID:
PMC5677977
.
Citations:
6
Bi WL
, Greenwald NF, Ramkissoon SH, Abedalthagafi M,
Coy SM
,
Ligon KL
,
Mei Y
,
MacConaill L
, Ducar M,
Min L
,
Santagata S
,
Kaiser UB
,
Beroukhim R
,
Laws ER
, Dunn IF. Clinical Identification of Oncogenic Drivers and Copy-Number Alterations in Pituitary Tumors. Endocrinology. 2017 07 01; 158(7):2284-2291.
PMID:
28486603
; PMCID:
PMC5505210
.
Citations:
26
Fields:
End
Endocrinology
Translation:
Humans
Cells
Ramkissoon SH,
Bandopadhayay P
, Hwang J, Ramkissoon LA, Greenwald NF, Schumacher SE, O'Rourke R, Pinches N, Ho P, Malkin H, Sinai C,
Filbin M
, Plant A,
Bi WL
,
Chang MS
,
Yang E
,
Wright KD
, Manley PE, Ducar M,
Alexandrescu S
,
Lidov H
, Delalle I, Goumnerova LC,
Church AJ
,
Janeway KA
,
Harris MH
,
MacConaill LE
, Folkerth RD,
Lindeman NI
,
Stiles CD
, Kieran MW,
Ligon AH
,
Santagata S
,
Dubuc AM
,
Chi SN
,
Beroukhim R
,
Ligon KL
. Clinical targeted exome-based sequencing in combination with genome-wide copy number profiling: precision medicine analysis of 203 pediatric brain tumors. Neuro Oncol. 2017 Jul 01; 19(7):986-996.
PMID:
28104717
; PMCID:
PMC5570190
.
Citations:
36
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Bi WL
, Greenwald NF, Abedalthagafi M,
Wala J
, Gibson WJ, Agarwalla PK, Horowitz P, Schumacher SE, Esaulova E,
Mei Y
, Chevalier A, Ducar M, Thorner AR, van Hummelen P,
Stemmer-Rachamimov A
, Artyomov M,
Al-Mefty O
,
Dunn GP
,
Santagata S
, Dunn IF,
Beroukhim R
. Genomic landscape of high-grade meningiomas. NPJ Genom Med. 2017; 2.
PMID:
28713588
; PMCID:
PMC5506858
.
Citations:
46
Shankar GM
, Abedalthagafi M, Vaubel RA,
Merrill PH
, Nayyar N, Gill CM,
Brewster R
,
Bi WL
, Agarwalla PK, Thorner AR,
Reardon DA
,
Al-Mefty O
,
Wen PY
,
Alexander BM
, van Hummelen P,
Batchelor TT
,
Ligon KL
,
Ligon AH
,
Meyerson M
, Dunn IF,
Beroukhim R
,
Louis DN
, Perry A,
Carter SL
, Giannini C,
Curry WT
,
Cahill DP
,
Barker FG
,
Brastianos PK
,
Santagata S
. Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas. Neuro Oncol. 2017 04 01; 19(4):535-545.
PMID:
28170043
; PMCID:
PMC5464371
.
Citations:
55
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Alvarez-Breckenridge C,
Miller JJ
, Nayyar N, Gill CM, Kaneb A, D'Andrea M,
Le LP
, Lee J, Cheng J, Zheng Z,
Butler WE
, Multani P, Chow Maneval E, Ha Paek S, Toyota BD,
Dias-Santagata D
,
Santagata S
,
Romero J
,
Shaw AT
, Farago AF, Yip S,
Cahill DP
,
Batchelor TT
,
Iafrate AJ
,
Brastianos PK
. Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor. NPJ Precis Oncol. 2017; 1(1):5.
PMID:
29872694
; PMCID:
PMC5871889
.
Citations:
22
Solomon IH
, Ciarlini PDSC,
Santagata S
, Ahmed AA,
De Girolami U
, Prasad S,
Mukerji SS
. Fatal Eastern Equine Encephalitis in a Patient on Maintenance Rituximab: A Case Report. Open Forum Infect Dis. 2017; 4(1):ofx021.
PMID:
28480291
; PMCID:
PMC5414020
.
Citations:
10
Huang KT, Ludy S, Calligaris D, Dunn IF,
Laws E
,
Santagata S
, Agar NY. Rapid Mass Spectrometry Imaging to Assess the Biochemical Profile of Pituitary Tissue for Potential Intraoperative Usage. Adv Cancer Res. 2017; 134:257-282.
PMID:
28110653
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Tsvetkov P, Sokol E, Jin D, Brune Z, Thiru P, Ghandi M, Garraway LA, Gupta PB,
Santagata S
, Whitesell L, Lindquist S. Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers. Proc Natl Acad Sci U S A. 2017 01 10; 114(2):382-387.
PMID:
28028240
; PMCID:
PMC5240730
.
Citations:
23
Fields:
Sci
Science
Translation:
Humans
Cells
Robinson LC,
Santagata S
, Hankinson TC. Potential evolution of neurosurgical treatment paradigms for craniopharyngioma based on genomic and transcriptomic characteristics. Neurosurg Focus. 2016 Dec; 41(6):E3.
PMID:
27903126
.
Citations:
6
Fields:
Neu
Neurosurgery
Translation:
Humans
Cells
Martinez-Gutierrez JC, D'Andrea MR,
Cahill DP
,
Santagata S
,
Barker FG
, Brastianos PK. Diagnosis and management of craniopharyngiomas in the era of genomics and targeted therapy. Neurosurg Focus. 2016 Dec; 41(6):E2.
PMID:
27903124
.
Citations:
8
Fields:
Neu
Neurosurgery
Translation:
Humans
Whitesell L,
Santagata S
. Susan Lindquist (1949-2016). Science. 2016 Nov 25; 354(6315):974.
PMID:
27884995
.
Citations:
1
Fields:
Sci
Science
Translation:
Humans
Strickland MR
, Gill CM, Nayyar N, D'Andrea MR, Thiede C, Juratli TA, Schackert G, Borger DR,
Santagata S
,
Frosch MP
,
Cahill DP
, Brastianos PK,
Barker FG
. Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas. J Neurosurg. 2017 08; 127(2):438-444.
PMID:
27885953
.
Citations:
19
Fields:
Neu
Neurosurgery
Translation:
Humans
Mei Y
,
Bi WL
, Greenwald NF, Du Z, Agar NY,
Kaiser UB
, Woodmansee WW,
Reardon DA
,
Freeman GJ
, Fecci PE,
Laws ER
,
Santagata S
,
Dunn GP
, Dunn IF. Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors. Oncotarget. 2016 Nov 22; 7(47):76565-76576.
PMID:
27655724
.
Citations:
44
Fields:
Neo
Neoplasms
Translation:
Humans
Dagogo-Jack I
, Gill CM,
Cahill DP
,
Santagata S
,
Brastianos PK
. Treatment of brain metastases in the modern genomic era. Pharmacol Ther. 2017 02; 170:64-72.
PMID:
27773784
.
Citations:
22
Fields:
Dru
Drug Therapy
Pha
Pharmacology
The
Therapeutics
Translation:
Humans
Bi WL
, Horowitz P, Greenwald NF, Abedalthagafi M, Agarwalla PK, Gibson WJ,
Mei Y
, Schumacher SE, Ben-David U, Chevalier A,
Carter S
, Tiao G,
Brastianos PK
,
Ligon AH
, Ducar M,
MacConaill L
,
Laws ER
,
Santagata S
,
Beroukhim R
, Dunn IF. Landscape of Genomic Alterations in Pituitary Adenomas. Clin Cancer Res. 2017 Apr 01; 23(7):1841-1851.
PMID:
27707790
; PMCID:
PMC5380512
.
Citations:
38
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Coy S
, Du Z, Sheu SH, Woo T, Rodriguez FJ, Kieran MW,
Santagata S
. Distinct patterns of primary and motile cilia in Rathke's cleft cysts and craniopharyngioma subtypes. Mod Pathol. 2016 12; 29(12):1446-1459.
PMID:
27562488
; PMCID:
PMC5442446
.
Citations:
5
Fields:
Pat
Pathology
Translation:
Humans
Cells
Coroller T, Bi W, Abedalthagafi M,
Aizer A
, Wu W, Greenwald N, Beroukhim R,
Al-Mefty O
,
Santagata S
, Dunn I, Alexander B, Huang R,
Aerts H
. SU-D-207B-02: Early Grade Classification in Meningioma Patients Combining Radiomics and Semantics Data. Med Phys. 2016 Jun; 43(6):3348-3349.
PMID:
28048264
.
Citations:
Bi WL
, Wu WW,
Santagata S
,
Reardon DA
, Dunn IF. Checkpoint inhibition in meningiomas. Immunotherapy. 2016 06; 8(6):721-31.
PMID:
27197540
.
Citations:
7
Fields:
All
Allergy and Immunology
The
Therapeutics
Translation:
Humans
Animals
Lu FK, Calligaris D, Olubiyi OI, Norton I, Yang W,
Santagata S
, Xie XS,
Golby AJ
, Agar NY. Label-Free Neurosurgical Pathology with Stimulated Raman Imaging. Cancer Res. 2016 06 15; 76(12):3451-62.
PMID:
27197198
; PMCID:
PMC4911248
.
Citations:
42
Fields:
Neo
Neoplasms
Translation:
Humans
Abedalthagafi MS,
Wu MP
,
Merrill PH
, Du Z, Woo T, Sheu SH,
Hurwitz S
,
Ligon KL
,
Santagata S
. Decreased FOXJ1 expression and its ciliogenesis programme in aggressive ependymoma and choroid plexus tumours. J Pathol. 2016 Mar; 238(4):584-97.
PMID:
26690880
; PMCID:
PMC5364032
.
Citations:
15
Fields:
Pat
Pathology
Translation:
Humans
Bandopadhayay P
, Ramkissoon LA, Jain P, Bergthold G,
Wala J
, Zeid R, Schumacher SE, Urbanski L, O'Rourke R, Gibson WJ, Pelton K, Ramkissoon SH,
Han HJ
, Zhu Y, Choudhari N, Silva A, Boucher K, Henn RE, Kang YJ, Knoff D, Paolella BR, Gladden-Young A, Varlet P,
Pages M
, Horowitz PM, Federation A, Malkin H, Tracy AA, Seepo S, Ducar M, Van Hummelen P, Santi M, Buccoliero AM, Scagnet M, Bowers DC, Giannini C, Puget S, Hawkins C, Tabori U, Klekner A, Bognar L, Burger PC, Eberhart C, Rodriguez FJ, Hill DA, Mueller S,
Haas-Kogan DA
, Phillips JJ,
Santagata S
,
Stiles CD
, Bradner JE, Jabado N, Goren A, Grill J,
Ligon AH
, Goumnerova L, Waanders AJ, Storm PB, Kieran MW,
Ligon KL
,
Beroukhim R
, Resnick AC. MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. Nat Genet. 2016 Mar; 48(3):273-82.
PMID:
26829751
; PMCID:
PMC4767685
.
Citations:
97
Fields:
Gen
Genetics
Translation:
Humans
Cells
Abedalthagafi M,
Bi WL
,
Aizer AA
,
Merrill PH
,
Brewster R
, Agarwalla PK, Listewnik ML,
Dias-Santagata D
, Thorner AR, Van Hummelen P,
Brastianos PK
,
Reardon DA
,
Wen PY
,
Al-Mefty O
, Ramkissoon SH, Folkerth RD,
Ligon KL
,
Ligon AH
,
Alexander BM
, Dunn IF,
Beroukhim R
,
Santagata S
. Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma. Neuro Oncol. 2016 05; 18(5):649-55.
PMID:
26826201
; PMCID:
PMC4827048
.
Citations:
95
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Bi WL
, Abedalthagafi M, Horowitz P, Agarwalla PK,
Mei Y
,
Aizer AA
,
Brewster R
, Dunn GP,
Al-Mefty O
, Alexander BM,
Santagata S
,
Beroukhim R
, Dunn IF. Genomic landscape of intracranial meningiomas. J Neurosurg. 2016 09; 125(3):525-35.
PMID:
26771848
.
Citations:
31
Fields:
Neu
Neurosurgery
Translation:
Humans
Fogh SE, Johnson DR,
Barker FG
, Brastianos PK, Clarke JL, Kaufmann TJ, Oberndorfer S, Preusser M, Raghunathan A,
Santagata S
, Theodosopoulos PV. Case-Based Review: meningioma. Neurooncol Pract. 2016 Jun; 3(2):120-134.
PMID:
31386096
; PMCID:
PMC6668267
.
Citations:
3
Brastianos PK
,
Santagata S
. ENDOCRINE TUMORS: BRAF V600E mutations in papillary craniopharyngioma. Eur J Endocrinol. 2016 Apr; 174(4):R139-44.
PMID:
26563980
; PMCID:
PMC4876601
.
Citations:
20
Fields:
End
Endocrinology
Translation:
Humans
Cells
Brastianos PK
,
Shankar GM
, Gill CM, Taylor-Weiner A, Nayyar N, Panka DJ, Sullivan RJ, Frederick DT, Abedalthagafi M,
Jones PS
, Dunn IF,
Nahed BV
,
Romero JM
,
Louis DN
,
Getz G
,
Cahill DP
,
Santagata S
,
Curry WT
,
Barker FG
. Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy. J Natl Cancer Inst. 2016 Feb; 108(2).
PMID:
26498373
; PMCID:
PMC4862417
.
Citations:
65
Fields:
Neo
Neoplasms
Translation:
Humans
Brastianos PK
,
Carter SL
,
Santagata S
,
Cahill DP
, Taylor-Weiner A, Jones RT,
Van Allen EM
,
Lawrence MS
, Horowitz PM, Cibulskis K,
Ligon KL
, Tabernero J, Seoane J, Martinez-Saez E,
Curry WT
, Dunn IF, Paek SH, Park SH, McKenna A, Chevalier A, Rosenberg M,
Barker FG
, Gill CM, Van Hummelen P, Thorner AR,
Johnson BE
,
Hoang MP
,
Choueiri TK
,
Signoretti S
, Sougnez C, Rabin MS,
Lin NU
,
Winer EP
,
Stemmer-Rachamimov A
,
Meyerson M
, Garraway L, Gabriel S,
Lander ES
,
Beroukhim R
,
Batchelor TT
, Baselga J,
Louis DN
,
Getz G
,
Hahn WC
. Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. Cancer Discov. 2015 Nov; 5(11):1164-1177.
PMID:
26410082
.
Citations:
366
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Tsvetkov P, Mendillo ML, Zhao J, Carette JE,
Merrill PH
, Cikes D, Varadarajan M, van Diemen FR, Penninger JM,
Goldberg AL
, Brummelkamp TR,
Santagata S
, Lindquist S. Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome. Elife. 2015 Sep 01; 4.
PMID:
26327695
.
Citations:
35
Fields:
Bio
Biology
Translation:
Humans
Cells
Aizer AA
, Abedalthagafi M,
Bi WL
, Horvath MC, Arvold ND,
Al-Mefty O
,
Lee EQ
,
Nayak L
,
Rinne ML
, Norden AD,
Reardon DA
,
Wen PY
,
Ligon KL
,
Ligon AH
,
Beroukhim R
, Dunn IF,
Santagata S
,
Alexander BM
. A prognostic cytogenetic scoring system to guide the adjuvant management of patients with atypical meningioma. Neuro Oncol. 2016 Feb; 18(2):269-74.
PMID:
26323607
; PMCID:
PMC4724184
.
Citations:
30
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Calligaris D, Feldman DR, Norton I, Olubiyi O, Changelian AN, Machaidze R, Vestal ML,
Laws ER
, Dunn IF,
Santagata S
, Agar NY. MALDI mass spectrometry imaging analysis of pituitary adenomas for near-real-time tumor delineation. Proc Natl Acad Sci U S A. 2015 Aug 11; 112(32):9978-83.
PMID:
26216958
; PMCID:
PMC4538649
.
Citations:
23
Fields:
Sci
Science
Translation:
Humans
Kertesz V, Calligaris D, Feldman DR, Changelian A,
Laws ER
,
Santagata S
, Agar NY, Van Berkel GJ. Profiling of adrenocorticotropic hormone and arginine vasopressin in human pituitary gland and tumor thin tissue sections using droplet-based liquid-microjunction surface-sampling-HPLC-ESI-MS-MS. Anal Bioanal Chem. 2015 Aug; 407(20):5989-98.
PMID:
26084546
.
Citations:
7
Fields:
Che
Chemistry Techniques
Translation:
Humans
Cells
Olubiyi OI, Ozdemir A, Incekara F,
Tie Y
, Dolati P,
Hsu L
,
Santagata S
, Chen Z, Rigolo L,
Golby AJ
. Intraoperative Magnetic Resonance Imaging in Intracranial Glioma Resection: A Single-Center, Retrospective Blinded Volumetric Study. World Neurosurg. 2015 Aug; 84(2):528-36.
PMID:
25937354
.
Citations:
9
Fields:
Neu
Neurosurgery
Translation:
Humans
Bergthold G,
Bandopadhayay P
, Hoshida Y, Ramkissoon S, Ramkissoon L, Rich B, Maire CL, Paolella BR, Schumacher SE, Tabak B, Ferrer-Luna R, Ozek M, Sav A,
Santagata S
,
Wen PY
, Goumnerova LC,
Ligon AH
,
Stiles C
,
Segal R
,
Golub T
, Grill J,
Ligon KL
,
Chan JA
, Kieran MW,
Beroukhim R
. Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype. Neuro Oncol. 2015 Nov; 17(11):1486-96.
PMID:
25825052
; PMCID:
PMC4648300
.
Citations:
17
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Cells
Abedalthagafi MS,
Bi WL
,
Merrill PH
, Gibson WJ,
Rose MF
, Du Z, Francis JM,
Du R
, Dunn IF,
Ligon AH
,
Beroukhim R
,
Santagata S
. ARID1A and TERT promoter mutations in dedifferentiated meningioma. Cancer Genet. 2015 Jun; 208(6):345-50.
PMID:
25963524
; PMCID:
PMC4882906
.
Citations:
35
Fields:
Gen
Genetics
Neo
Neoplasms
Translation:
Humans
Cells
Du Z, Abedalthagafi M,
Aizer AA
, McHenry AR, Sun HH, Bray MA, Viramontes O, Machaidze R,
Brastianos PK
,
Reardon DA
, Dunn IF,
Freeman GJ
,
Ligon KL
, Carpenter AE,
Alexander BM
, Agar NY,
Rodig SJ
, Bradshaw EM,
Santagata S
. Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma. Oncotarget. 2015 Mar 10; 6(7):4704-16.
PMID:
25609200
; PMCID:
PMC4467109
.
Citations:
54
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ramkissoon SH,
Bi WL
, Schumacher SE, Ramkissoon LA, Haidar S, Knoff D,
Dubuc A
, Brown L, Burns M, Cryan JB, Abedalthagafi M, Kang YJ, Schultz N,
Reardon DA
,
Lee EQ
,
Rinne ML
, Norden AD,
Nayak L
, Ruland S, Doherty LM, LaFrankie DC, Horvath M,
Aizer AA
,
Russo A
, Arvold ND,
Claus EB
,
Al-Mefty O
, Johnson MD,
Golby AJ
, Dunn IF,
Chiocca EA
,
Trippa L
,
Santagata S
, Folkerth RD,
Kantoff P
,
Rollins BJ
,
Lindeman NI
,
Wen PY
,
Ligon AH
,
Beroukhim R
,
Alexander BM
,
Ligon KL
. Clinical implementation of integrated whole-genome copy number and mutation profiling for glioblastoma. Neuro Oncol. 2015 Oct; 17(10):1344-55.
PMID:
25754088
; PMCID:
PMC4578577
.
Citations:
24
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Calligaris D, Feldman DR, Norton I,
Brastianos PK
, Dunn IF,
Santagata S
, Agar NY. Molecular typing of Meningiomas by Desorption Electrospray Ionization Mass Spectrometry Imaging for Surgical Decision-Making. Int J Mass Spectrom. 2015 Feb 01; 377:690-698.
PMID:
25844057
; PMCID:
PMC4379512
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Citations:
16
Shankar GM
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Curry WT
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Nahed BV
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Shin JH
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Stemmer-Rachamimov AO
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PMID:
25589003
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Citations:
25
Fields:
Neu
Neurology
Translation:
Humans
Cells
Whitesell L,
Santagata S
, Mendillo ML,
Lin NU
, Proia DA, Lindquist S. HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):18297-302.
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25489079
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PMC4280614
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