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Babak Javid, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chen Y, Sun T, Bi Z, Ni JQ, Pastor-Pareja JC, Javid B. Premature termination codon readthrough in Drosophila varies in a developmental and tissue-specific manner. Sci Rep. 2020 May 22; 10(1):8485. PMID: 32444687.
    Citations:    
  2. Wang BW, Zhu JH, Javid B. Clinically relevant mutations in mycobacterial LepA cause rifampicin-specific phenotypic resistance. Sci Rep. 2020 May 21; 10(1):8402. PMID: 32439911.
    Citations:    
  3. Staples E, Simeoni I, Stephens JC, Allen HL, Wright P, Davies EG, Javid B, Gkrania-Klotsas E, Gattens M, Firth H, Shamardina O, Deevi SVV, Prapa M, Uttenthal B, Kumararatne D, Thaventhiran JED. ADA2 deficiency complicated by EBV-driven lymphoproliferative disease. Clin Immunol. 2020 Jun; 215:108443. PMID: 32353633.
    Citations:    
  4. Javid B, Weekes MP, Matheson NJ. Covid-19: should the public wear face masks? BMJ. 2020 04 09; 369:m1442. PMID: 32273278.
    Citations:    
  5. Zhang YW, Zhu JH, Wang ZQ, Wu Y, Meng X, Zheng X, Javid B. HspX promotes the polar localization of mycobacterial protein aggregates. Sci Rep. 2019 10 10; 9(1):14571. PMID: 31601950.
    Citations:    
  6. Wu J, Mu R, Sun M, Zhao N, Pan M, Li H, Dong Y, Sun Z, Bai J, Hu M, Nathan CF, Javid B, Liu G. Derivatives of Natural Product Agrimophol as Disruptors of Intrabacterial pH Homeostasis in Mycobacterium tuberculosis. ACS Infect Dis. 2019 07 12; 5(7):1087-1104. PMID: 31016962.
    Citations:    
  7. Chen YX, Pan M, Chen YM, Javid B. Measurement of Specific Mycobacterial Mistranslation Rates with Gain-of-function Reporter Systems. J Vis Exp. 2019 04 26; (146). PMID: 31081825.
    Citations:    
  8. Zhu JH, Wang BW, Pan M, Zeng YN, Rego H, Javid B. Rifampicin can induce antibiotic tolerance in mycobacteria via paradoxical changes in rpoB transcription. Nat Commun. 2018 10 11; 9(1):4218. PMID: 30310059.
    Citations:    Fields:    Translation:HumansCells
  9. Chen YX, Javid B. More than merely drug resistance. Nat Microbiol. 2018 10; 3(10):1078-1079. PMID: 30254331.
    Citations:    Fields:    
  10. Edwards D, Kent D, Lester C, Brown CS, Murphy ME, Brown NM, Sule O, Itani A, Chand M, Trindall A, Pearson C, Roddick I, Fry NK, Hoffmann J, Iyanger N, Kemp L, White J, Javid B, Ramsay ID, Zenner D, Ahmed A, Amirthalingam G, Salimee S, Litt D, Reacher M. Transmission of toxigenic Corynebacterium diphtheriae by a fully immunised resident returning from a visit to West Africa, United Kingdom, 2017. Euro Surveill. 2018 09; 23(39). PMID: 30280689.
    Citations:    Fields:    
  11. Li H, Javid B. Antibodies and tuberculosis: finally coming of age? Nat Rev Immunol. 2018 09; 18(9):591-596. PMID: 29872140.
    Citations: 1     Fields:    
  12. Chaudhuri S, Li L, Zimmerman M, Chen Y, Chen YX, Toosky MN, Gardner M, Pan M, Li YY, Kawaji Q, Zhu JH, Su HW, Martinot AJ, Rubin EJ, Dartois VA, Javid B. Kasugamycin potentiates rifampicin and limits emergence of resistance in Mycobacterium tuberculosis by specifically decreasing mycobacterial mistranslation. Elife. 2018 08 28; 7. PMID: 30152756.
    Citations:    Fields:    Translation:AnimalsCells
  13. Li H, Wang XX, Wang B, Fu L, Liu G, Lu Y, Cao M, Huang H, Javid B. Latently and uninfected healthcare workers exposed to TB make protective antibodies against Mycobacterium tuberculosis. Proc Natl Acad Sci U S A. 2017 05 09; 114(19):5023-5028. PMID: 28438994.
    Citations: 6     Fields:    Translation:HumansAnimalsCellsPHPublic HealthCTClinical Trials
  14. Li H, Wu M, Shi Y, Javid B. Over-Expression of the Mycobacterial Trehalose-Phosphate Phosphatase OtsB2 Results in a Defect in Macrophage Phagocytosis Associated with Increased Mycobacterial-Macrophage Adhesion. Front Microbiol. 2016; 7:1754. PMID: 27867377.
    Citations: 1     
  15. Su HW, Zhu JH, Li H, Cai RJ, Ealand C, Wang X, Chen YX, Kayani MU, Zhu TF, Moradigaravand D, Huang H, Kana BD, Javid B. The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity. Nat Microbiol. 2016 Aug 26; 1(11):16147. PMID: 27564922.
    Citations: 16     Fields:    Translation:Cells
  16. Long J, Basu Roy R, Zhang YJ, Antrobus R, Du Y, Smith DL, Weekes MP, Javid B. Plasma Membrane Profiling Reveals Upregulation of ABCA1 by Infected Macrophages Leading to Restriction of Mycobacterial Growth. Front Microbiol. 2016; 7:1086. PMID: 27462310.
    Citations: 3     
  17. Moradigaravand D, Grandjean L, Martinez E, Li H, Zheng J, Coronel J, Moore D, Török ME, Sintchenko V, Huang H, Javid B, Parkhill J, Peacock SJ, Köser CU. dfrA thyA Double Deletion in para-Aminosalicylic Acid-Resistant Mycobacterium tuberculosis Beijing Strains. Antimicrob Agents Chemother. 2016 06; 60(6):3864-7. PMID: 27021327.
    Citations: 3     Fields:    Translation:HumansCells
  18. Javid B, Török ME. Whole-genome sequencing for the diagnosis of drug-resistant tuberculosis. Lancet Infect Dis. 2016 Jan; 16(1):17. PMID: 26738825.
    Citations:    Fields:    Translation:HumansCells
  19. Leng T, Pan M, Xu X, Javid B. Translational misreading in Mycobacterium smegmatis increases in stationary phase. Tuberculosis (Edinb). 2015 Dec; 95(6):678-681. PMID: 26542220.
    Citations: 6     Fields:    Translation:Cells
  20. Liu C, Kong C, Wu G, Zhu J, Javid B, Qian F. Uniform and amorphous rifampicin microspheres obtained by freezing induced LLPS during lyophilization. Int J Pharm. 2015 Nov 10; 495(1):500-507. PMID: 26383842.
    Citations:    Fields:    Translation:HumansCells
  21. Li H, Kayani Mu, Gu Y, Wang X, Zhu T, Duan H, Ma Y, Huang H, Javid B. Transmitted Extended-Spectrum Extensively Drug-Resistant Tuberculosis in Beijing, China, with Discordant Whole-Genome Sequencing Analysis Results. J Clin Microbiol. 2015 Aug; 53(8):2781-4. PMID: 26063862.
    Citations: 3     Fields:    Translation:HumansCells
  22. Zhu JH, Javid B. Tuberculosis: hey there, lonely guy! Mol Cell. 2015 Mar 19; 57(6):951-952. PMID: 25794612.
    Citations:    Fields:    Translation:AnimalsCells
  23. Köser CU, Javid B, Liddell K, Ellington MJ, Feuerriegel S, Niemann S, Brown NM, Burman WJ, Abubakar I, Ismail NA, Moore D, Peacock SJ, Török ME. Drug-resistance mechanisms and tuberculosis drugs. Lancet. 2015 Jan 24; 385(9965):305-7. PMID: 25706840.
    Citations: 5     Fields:    Translation:Humans
  24. Ribas de Pouplana L, Santos MA, Zhu JH, Farabaugh PJ, Javid B. Protein mistranslation: friend or foe? Trends Biochem Sci. 2014 Aug; 39(8):355-62. PMID: 25023410.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  25. Wang X, Li H, Jiang G, Zhao L, Ma Y, Javid B, Huang H. Prevalence and drug resistance of nontuberculous mycobacteria, northern China, 2008-2011. Emerg Infect Dis. 2014 Jul; 20(7):1252-3. PMID: 24959839.
    Citations: 3     Fields:    Translation:HumansCells
  26. Toosky M, Javid B. Novel diagnostics and therapeutics for drug-resistant tuberculosis. Br Med Bull. 2014 Jun; 110(1):129-40. PMID: 24810849.
    Citations: 2     Fields:    Translation:HumansCells
  27. Javid B, Sorrentino F, Toosky M, Zheng W, Pinkham JT, Jain N, Pan M, Deighan P, Rubin EJ. Mycobacterial mistranslation is necessary and sufficient for rifampicin phenotypic resistance. Proc Natl Acad Sci U S A. 2014 Jan 21; 111(3):1132-7. PMID: 24395793.
    Citations: 36     Fields:    Translation:Cells
  28. Wong SY, Javid B, Addepalli B, Piszczek G, Strader MB, Limbach PA, Barry CE. Functional role of methylation of G518 of the 16S rRNA 530 loop by GidB in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2013 Dec; 57(12):6311-8. PMID: 24100503.
    Citations: 6     Fields:    Translation:Cells
  29. La Rosa V, Poce G, Canseco JO, Buroni S, Pasca MR, Biava M, Raju RM, Porretta GC, Alfonso S, Battilocchio C, Javid B, Sorrentino F, Ioerger TR, Sacchettini JC, Manetti F, Botta M, De Logu A, Rubin EJ, De Rossi E. MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212. Antimicrob Agents Chemother. 2012 Jan; 56(1):324-31. PMID: 22024828.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  30. Javid B, Derbyshire KM. Nanotubes: shaking hands, talking, or sharing? Front Microbiol. 2011; 2:95. PMID: 21833333.
    Citations:    
  31. Su Y, Blake-Palmer KG, Sorrell S, Javid B, Bowers K, Zhou A, Chang SH, Qamar S, Karet FE. Human H+ATPase a4 subunit mutations causing renal tubular acidosis reveal a role for interaction with phosphofructokinase-1. Am J Physiol Renal Physiol. 2008 Oct; 295(4):F950-8. PMID: 18632794.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  32. Daly ML, Cartwright DJ, Lehner PJ, Javid B. A 58-year-old woman with abdominal symptoms and elevated C-reactive protein. PLoS Med. 2008 Jul 01; 5(7):e149. PMID: 18597553.
    Citations:    Fields:    Translation:Humans
  33. Phuah CL, Javid B, Aliyu SH, Lever AM. A case of Mycoplasma hominis septic arthritis postpartum. J Infect. 2007 Nov; 55(5):e135-7. PMID: 17892899.
    Citations:    Fields:    Translation:HumansCells
  34. Javid B, MacAry PA, Lehner PJ. Structure and function: heat shock proteins and adaptive immunity. J Immunol. 2007 Aug 15; 179(4):2035-40. PMID: 17675458.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  35. Javid B, Aliyu SH, Save VE, Carmichael AJ, Lever AM. Schistosomal colonic polyposis in an HIV-positive man. AIDS. 2007 Jan 30; 21(3):386-8. PMID: 17255754.
    Citations: 2     Fields:    Translation:HumansCells
  36. Javid B, MacAry PA, Oehlmann W, Singh M, Lehner PJ. Peptides complexed with the protein HSP70 generate efficient human cytolytic T-lymphocyte responses. Biochem Soc Trans. 2004 Aug; 32(Pt 4):622-5. PMID: 15270691.
    Citations: 3     Fields:    Translation:HumansCells
  37. Watkins NA, Dafforn TR, Kuijpers M, Brown C, Javid B, Lehner PJ, Navarrete C, Ouwehand WH. Molecular studies of anti-HLA-A2 using light-chain shuffling: a structural model for HLA antibody binding. Tissue Antigens. 2004 Apr; 63(4):345-54. PMID: 15009806.
    Citations:    Fields:    Translation:HumansCells
  38. MacAry PA, Javid B, Floto RA, Smith KG, Oehlmann W, Singh M, Lehner PJ. HSP70 peptide binding mutants separate antigen delivery from dendritic cell stimulation. Immunity. 2004 Jan; 20(1):95-106. PMID: 14738768.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  39. Moore DA, Lightstone L, Javid B, Friedland JS. High rates of tuberculosis in end-stage renal failure: the impact of international migration. Emerg Infect Dis. 2002 Jan; 8(1):77-8. PMID: 11749753.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.