Profiles Header - Harvard Catalyst Profiles Header – Harvard Catalyst

Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Choukri Mekkaoui, Ph.D.

Title
Institution
Department
Address

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL131635 (MEKKAOUI, CHOUKRI) Apr 1, 2016 - Mar 31, 2021
    NIH
    Free-Breathing Diffusion Tensor MRI in Patients Following Myocardial Infarction
    Role: Principal Investigator
  2. R56HL125590 (MEKKAOUI, CHOUKRI) Sep 4, 2015 - Aug 31, 2016
    NIH
    Tracking Cardiac Remodeling in Humans Using In Vivo Diffusion Tensor MRI
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Fan Q, Nummenmaa A, Wichtmann B, Witzel T, Mekkaoui C, Schneider W, Wald LL, Huang SY. A comprehensive diffusion MRI dataset acquired on the MGH Connectome scanner in a biomimetic brain phantom. Data Brief. 2018 Jun; 18:334-339. PMID: 29896520.
    View in: PubMed
  2. Mekkaoui C, Jackowski MP, Kostis WJ, Stoeck CT, Thiagalingam A, Reese TG, Reddy VY, Ruskin JN, Kozerke S, Sosnovik DE. Myocardial Scar Delineation Using Diffusion Tensor Magnetic Resonance Tractography. J Am Heart Assoc. 2018 Feb 02; 7(3). PMID: 29420216.
    View in: PubMed
  3. Fan Q, Nummenmaa A, Wichtmann B, Witzel T, Mekkaoui C, Schneider W, Wald LL, Huang SY. Validation of diffusion MRI estimates of compartment size and volume fraction in a biomimetic brain phantom using a human MRI scanner with 300?mT/m maximum gradient strength. Neuroimage. 2018 Nov 15; 182:469-478. PMID: 29337276.
    View in: PubMed
  4. Mekkaoui C, Reese TG, Jackowski MP, Cauley SF, Setsompop K, Bhat H, Sosnovik DE. Diffusion Tractography of the Entire Left Ventricle by Using Free-breathing Accelerated Simultaneous Multisection Imaging. Radiology. 2017 03; 282(3):850-856. PMID: 27681278.
    View in: PubMed
  5. Mekkaoui C, Metellus P, Kostis WJ, Martuzzi R, Pereira FR, Beregi JP, Reese TG, Constable TR, Jackowski MP. Diffusion Tensor Imaging in Patients with Glioblastoma Multiforme Using the Supertoroidal Model. PLoS One. 2016; 11(1):e0146693. PMID: 26761637; PMCID: PMC4711969.
  6. Mekkaoui C, Reese TG, Jackowski MP, Bhat H, Sosnovik DE. Diffusion MRI in the heart. NMR Biomed. 2017 Mar; 30(3). PMID: 26484848.
    View in: PubMed
  7. Greffier J, Macri F, Larbi A, Fernandez A, Pereira F, Mekkaoui C, Beregi JP. Dose reduction with iterative reconstruction in multi-detector CT: What is the impact on deformation of circular structures in phantom study? Diagn Interv Imaging. 2016 Feb; 97(2):187-96. PMID: 26298669.
    View in: PubMed
  8. Pereira FR, Macri F, Jackowski MP, Kostis WJ, Gris JC, Beregi JP, Mekkaoui C. Diffusion tensor imaging in patients with obstetric antiphospholipid syndrome without neuropsychiatric symptoms. Eur Radiol. 2016 Apr; 26(4):959-68. PMID: 26201292.
    View in: PubMed
  9. Greffier J, Macri F, Larbi A, Fernandez A, Khasanova E, Pereira F, Mekkaoui C, Beregi JP. Dose reduction with iterative reconstruction: Optimization of CT protocols in clinical practice. Diagn Interv Imaging. 2015 May; 96(5):477-86. PMID: 25797211.
    View in: PubMed
  10. Stoeck CT, Kalinowska A, von Deuster C, Harmer J, Chan RW, Niemann M, Manka R, Atkinson D, Sosnovik DE, Mekkaoui C, Kozerke S. Dual-phase cardiac diffusion tensor imaging with strain correction. PLoS One. 2014; 9(9):e107159. PMID: 25191900; PMCID: PMC4156436.
  11. Sosnovik DE, Mekkaoui C, Huang S, Chen HH, Dai G, Stoeck CT, Ngoy S, Guan J, Wang R, Kostis WJ, Jackowski MP, Wedeen VJ, Kozerke S, Liao R. Microstructural impact of ischemia and bone marrow-derived cell therapy revealed with diffusion tensor magnetic resonance imaging tractography of the heart in vivo. Circulation. 2014 Apr 29; 129(17):1731-41. PMID: 24619466.
    View in: PubMed
  12. Mekkaoui C, Porayette P, Jackowski MP, Kostis WJ, Dai G, Sanders S, Sosnovik DE. Diffusion MRI tractography of the developing human fetal heart. PLoS One. 2013; 8(8):e72795. PMID: 23991152; PMCID: PMC3753231.
  13. Chen HH, Mekkaoui C, Cho H, Ngoy S, Marinelli B, Waterman P, Nahrendorf M, Liao R, Josephson L, Sosnovik DE. Fluorescence tomography of rapamycin-induced autophagy and cardioprotection in vivo. Circ Cardiovasc Imaging. 2013 May 01; 6(3):441-7. PMID: 23537953; PMCID: PMC3805276.
  14. McGill LA, Ismail TF, Nielles-Vallespin S, Ferreira P, Scott AD, Roughton M, Kilner PJ, Ho SY, McCarthy KP, Gatehouse PD, de Silva R, Speier P, Feiweier T, Mekkaoui C, Sosnovik DE, Prasad SK, Firmin DN, Pennell DJ. Reproducibility of in-vivo diffusion tensor cardiovascular magnetic resonance in hypertrophic cardiomyopathy. J Cardiovasc Magn Reson. 2012 Dec 24; 14:86. PMID: 23259835; PMCID: PMC3551746.
  15. Mekkaoui C, Huang S, Chen HH, Dai G, Reese TG, Kostis WJ, Thiagalingam A, Maurovich-Horvat P, Ruskin JN, Hoffmann U, Jackowski MP, Sosnovik DE. Fiber architecture in remodeled myocardium revealed with a quantitative diffusion CMR tractography framework and histological validation. J Cardiovasc Magn Reson. 2012 Oct 12; 14:70. PMID: 23061749; PMCID: PMC3506570.
  16. Nielles-Vallespin S, Mekkaoui C, Gatehouse P, Reese TG, Keegan J, Ferreira PF, Collins S, Speier P, Feiweier T, de Silva R, Jackowski MP, Pennell DJ, Sosnovik DE, Firmin D. In vivo diffusion tensor MRI of the human heart: reproducibility of breath-hold and navigator-based approaches. Magn Reson Med. 2013 Aug; 70(2):454-65. PMID: 23001828; PMCID: PMC3864770.
  17. Huang S, Chen HH, Yuan H, Dai G, Schuhle DT, Mekkaoui C, Ngoy S, Liao R, Caravan P, Josephson L, Sosnovik DE. Molecular MRI of acute necrosis with a novel DNA-binding gadolinium chelate: kinetics of cell death and clearance in infarcted myocardium. Circ Cardiovasc Imaging. 2011 Nov; 4(6):729-37. PMID: 21836081; PMCID: PMC3370828.
  18. Kerbaul F, By Y, Gariboldi V, Mekkaoui C, Fesler P, Collart F, Brimioulle S, Jammes Y, Ruf J, Guieu R. Acute pulmonary embolism decreases adenosine plasma levels in anesthetized pigs. ISRN Cardiol. 2011; 2011:750301. PMID: 22347654; PMCID: PMC3262497.
  19. Liu YH, Sahul Z, Weyman CA, Dione DP, Dobrucki WL, Mekkaoui C, Brennan MP, Ryder WJ, Sinusas AJ. Accuracy and reproducibility of absolute quantification of myocardial focal tracer uptake from molecularly targeted SPECT/CT: a canine validation. J Nucl Med. 2011 Mar; 52(3):453-60. PMID: 21321271; PMCID: PMC3137905.
  20. Mekkaoui C, Jadbabaie F, Dione DP, Meoli DF, Purushothaman K, Belardinelli L, Sinusas AJ. Effects of adenosine and a selective A2A adenosine receptor agonist on hemodynamic and thallium-201 and technetium-99m-sestaMIBI biodistribution and kinetics. JACC Cardiovasc Imaging. 2009 Oct; 2(10):1198-208. PMID: 19833310.
    View in: PubMed
  21. Metellus P, Dutertre G, Mekkaoui C, Nanni I, Fuentes S, Ait-Ameur A, Chinot O, Dufour H, Figarella-Branger D, Cordoliani YS, Grisoli F. [Value of relative cerebral blood volume measurement using perfusion MRI in glioma management]. Neurochirurgie. 2008 Aug; 54(4):503-11. PMID: 18573509.
    View in: PubMed
  22. Donnet A, Metellus P, Levrier O, Mekkaoui C, Fuentes S, Dufour H, Conrath J, Grisoli F. Endovascular treatment of idiopathic intracranial hypertension: clinical and radiologic outcome of 10 consecutive patients. Neurology. 2008 Feb 19; 70(8):641-7. PMID: 18285539.
    View in: PubMed
  23. Fuchs AT, Kuehnl A, Pelisek J, Rolland PH, Mekkaoui C, Netz H, Nikol S. Meta-analysis shows similar risk of thrombosis after drug-eluting stent, bare-metal stent, or angioplasty. Endothelium. 2008 Jan-Feb; 15(1):93-100. PMID: 18568949.
    View in: PubMed
  24. Fuchs AT, Kuehnl A, Pelisek J, Rolland PH, Mekkaoui C, Netz H, Nikol S. Inhibition of restenosis formation without compromising reendothelialization as a potential solution to thrombosis following angioplasty? Endothelium. 2008 Jan-Feb; 15(1):85-92. PMID: 18568948.
    View in: PubMed
  25. Kerbaul F, Gariboldi V, Giorgi R, Mekkaoui C, Guieu R, Fesler P, Gouin F, Brimioulle S, Collart F. Effects of levosimendan on acute pulmonary embolism-induced right ventricular failure. Crit Care Med. 2007 Aug; 35(8):1948-54. PMID: 17568324.
    View in: PubMed
  26. Golda A, Pelisek J, Klocke R, Engelmann MG, Rolland PH, Mekkaoui C, Nikol S. Small poly-L-lysines improve cationic lipid-mediated gene transfer in vascular cells in vitro and in vivo. J Vasc Res. 2007; 44(4):273-82. PMID: 17406119.
    View in: PubMed
  27. Pelisek J, Fuchs AT, Kuehnl A, Tian W, Kuhlmann MT, Rolland PH, Mekkaoui C, Gaedtke L, Nikol S. C-type natriuretic peptide for reduction of restenosis: gene transfer is superior over single peptide administration. J Gene Med. 2006 Jul; 8(7):835-44. PMID: 16602133.
    View in: PubMed
  28. Kerbaul F, Bellezza M, Mekkaoui C, Feier H, Guidon C, Gouvernet J, Rolland PH, Gouin F, Mesana T, Collart F. Sevoflurane alters right ventricular performance but not pulmonary vascular resistance in acutely instrumented anesthetized pigs. J Cardiothorac Vasc Anesth. 2006 Apr; 20(2):209-16. PMID: 16616661.
    View in: PubMed
  29. Rolland PH, Vidal V, Mekkaoui C, Bertrand MF, Levrier O, Bartoli JM. Embolization-driven occlusion of the abdominal aortic aneurysmal sac as the basis of prevention of endoleaks in a new swine model. Eur J Vasc Endovasc Surg. 2006 Jan; 31(1):28-35. PMID: 16202632.
    View in: PubMed
  30. Kühnl A, Pelisek J, Tian W, Kuhlmann M, Rolland PH, Mekkaoui C, Fuchs A, Nikol S. C-type natriuretic peptide inhibits constrictive remodeling without compromising re-endothelialization in balloon-dilated renal arteries. J Endovasc Ther. 2005 Apr; 12(2):171-82. PMID: 15823063.
    View in: PubMed
  31. Rolland PH, Mekkaoui C, Vidal V, Berry JL, Moore JE, Moreno M, Amabile P, Bartoli JM. Compliance matching stent placement in the carotid artery of the swine promotes optimal blood flow and attenuates restenosis. Eur J Vasc Endovasc Surg. 2004 Oct; 28(4):431-8. PMID: 15350569.
    View in: PubMed
  32. Collart F, Kerbaul F, Mekkaoui C, Riberi A, Gariboldi V, Rolland PH, Métras D, Mesana TG. Balloon-pump-induced pulsatility improves coronary and carotid flows in an experimental model of BioMedicus left ventricular assistance. Artif Organs. 2004 Aug; 28(8):743-6. PMID: 15270957.
    View in: PubMed
  33. Pelisek J, Kuehnl A, Rolland PH, Mekkaoui C, Fuchs A, Walker GF, Ogris M, Wagner E, Nikol S. Functional analysis of genomic DNA, cDNA, and nucleotide sequence of the mature C-type natriuretic peptide gene in vascular cells. Arterioscler Thromb Vasc Biol. 2004 Sep; 24(9):1646-51. PMID: 15231517.
    View in: PubMed
  34. Engelmann MG, Shimizu M, Pelisek J, Fuchs A, Golda A, Mekkaoui C, Fraunberger P, Rolland PH, Nikol S. Comparison of surgical versus endovascular occlusion models in pig femoral arteries. J Endovasc Ther. 2004 Feb; 11(1):71-9. PMID: 14748626.
    View in: PubMed
  35. Mekkaoui C, Rolland PH, Friggi A, Rasigni M, Mesana TG. Pressure-flow loops and instantaneous input impedance in the thoracic aorta: another way to assess the effect of aortic bypass graft implantation on myocardial, brain, and subdiaphragmatic perfusion. J Thorac Cardiovasc Surg. 2003 Mar; 125(3):699-710. PMID: 12658214.
    View in: PubMed
  36. Levrier O, Mekkaoui C, Rolland PH, Murphy K, Cabrol P, Moulin G, Bartoli JM, Raybaud C. Efficacy and low vascular toxicity of embolization with radical versus anionic polymerization of n-butyl-2-cyanoacrylate (NBCA). An experimental study in the swine. J Neuroradiol. 2003 Mar; 30(2):95-102. PMID: 12717295.
    View in: PubMed
  37. Pelisek J, Fuchs A, Engelmann MG, Shimizu M, Golda A, Mekkaoui C, Rolland PH, Nikol S. Vascular endothelial growth factor response in porcine coronary and peripheral arteries using nonsurgical occlusion model, local delivery, and liposome-mediated gene transfer. Endothelium. 2003; 10(4-5):247-55. PMID: 14660085.
    View in: PubMed
  38. Rolland PH, Mekkaoui C, Palassi M, Friggi A, Moulin G, Piquet P, Bartoli JM. Efficacy of local molsidomine delivery from a hydrogel-coated angioplasty balloon catheter in the atherosclerotic porcine model. Cardiovasc Intervent Radiol. 2003 Jan-Feb; 26(1):65-72. PMID: 12491015.
    View in: PubMed
  39. Nikol S, Pelisek J, Engelmann MG, Shimizu M, Fuchs A, Golda A, Armeanu S, Mekkaoui C, Rolland PH. Vascular endothelial growth factor (VEGF165) and its influence on angiogenesis versus arteriogenesis in different vascular beds. J Endovasc Ther. 2002 Dec; 9(6):842-54. PMID: 12546587.
    View in: PubMed
  40. Feier H, Mekkaoui C, Drevet JB, Sérée Y, Richomme C, Rolland PH, Mesana TG. A novel, valveless ventricular assist device: the FishTail pump. First experimental in vivo studies. Artif Organs. 2002 Dec; 26(12):1026-31. PMID: 12460380.
    View in: PubMed
  41. Pelisek J, Engelmann MG, Golda A, Fuchs A, Armeanu S, Shimizu M, Mekkaoui C, Rolland PH, Nikol S. Optimization of nonviral transfection: variables influencing liposome-mediated gene transfer in proliferating vs. quiescent cells in culture and in vivo using a porcine restenosis model. J Mol Med (Berl). 2002 Nov; 80(11):724-36. PMID: 12436349.
    View in: PubMed
  42. Nikol S, Engelmann MG, Pelisek J, Fuchs A, Golda A, Shimizu M, Mekkaoui C, Rolland PH. Local perivascular application of low amounts of a plasmid encoding for vascular endothelial growth factor (VEGF165) is efficient for therapeutic angiogenesis in pigs. Acta Physiol Scand. 2002 Oct; 176(2):151-9. PMID: 12354175.
    View in: PubMed
  43. Rolland PH, Bartoli JM, Piquet P, Mekkaoui C, Nott SH, Moulin G, Amabile P, Mesana T. Local delivery of NO-donor molsidomine post-PTA improves haemodynamics, wall mechanics and histomorphometry in atherosclerotic porcine SFA. Eur J Vasc Endovasc Surg. 2002 Mar; 23(3):226-33. PMID: 11914009.
    View in: PubMed
  44. Berry JL, Manoach E, Mekkaoui C, Rolland PH, Moore JE, Rachev A. Hemodynamics and wall mechanics of a compliance matching stent: in vitro and in vivo analysis. J Vasc Interv Radiol. 2002 Jan; 13(1):97-105. PMID: 11788701.
    View in: PubMed
  45. Mekkaoui C, Friggi A, Rolland PH, Bodard H, Piquet P, Bartoli JM, Mesana T. Simultaneous measurements of arterial diameter and blood pressure to determine the arterial compliance, wall mechanics and stresses in vivo. Eur J Vasc Endovasc Surg. 2001 Mar; 21(3):208-13. PMID: 11352678.
    View in: PubMed
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Mekkaoui's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (277)
Explore
_
Co-Authors (18)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
Tool Page Footer - Harvard Catalyst Tool Page Footer – Harvard Catalyst
Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.