Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Jonathan A. Fletcher, M.D.

Co-Author

This page shows the publications co-authored by Jonathan Fletcher and Wenbin Ou.
Connection Strength

5.207
  1. Cyclin D1 is a mediator of gastrointestinal stromal tumor KIT-independence. Oncogene. 2019 09; 38(39):6615-6629.
    View in: PubMed
    Score: 0.871
  2. Co-targeting of FAK and MDM2 triggers additive anti-proliferative effects in mesothelioma via a coordinated reactivation of p53. Br J Cancer. 2016 Nov 08; 115(10):1253-1263.
    View in: PubMed
    Score: 0.718
  3. HDACi inhibits liposarcoma via targeting of the MDM2-p53 signaling axis and PTEN, irrespective of p53 mutational status. Oncotarget. 2015 Apr 30; 6(12):10510-20.
    View in: PubMed
    Score: 0.649
  4. Targeted inhibition of multiple receptor tyrosine kinases in mesothelioma. Neoplasia. 2011 Jan; 13(1):12-22.
    View in: PubMed
    Score: 0.481
  5. AXL regulates mesothelioma proliferation and invasiveness. Oncogene. 2011 Apr 07; 30(14):1643-52.
    View in: PubMed
    Score: 0.478
  6. Protein kinase C-theta regulates KIT expression and proliferation in gastrointestinal stromal tumors. Oncogene. 2008 Sep 18; 27(42):5624-34.
    View in: PubMed
    Score: 0.402
  7. Coordinated targeting of CK2 and KIT in gastrointestinal stromal tumours. Br J Cancer. 2020 02; 122(3):372-381.
    View in: PubMed
    Score: 0.223
  8. Dual Targeting of Insulin Receptor and KIT in Imatinib-Resistant Gastrointestinal Stromal Tumors. Cancer Res. 2017 09 15; 77(18):5107-5117.
    View in: PubMed
    Score: 0.190
  9. ALK oncoproteins in atypical inflammatory myofibroblastic tumours: novel RRBP1-ALK fusions in epithelioid inflammatory myofibroblastic sarcoma. J Pathol. 2017 Feb; 241(3):316-323.
    View in: PubMed
    Score: 0.182
  10. Downregulation of cyclin D1 sensitizes cancer cells to MDM2 antagonist Nutlin-3. Oncotarget. 2016 May 31; 7(22):32652-63.
    View in: PubMed
    Score: 0.175
  11. Multipoint targeting of the PI3K/mTOR pathway in mesothelioma. Br J Cancer. 2014 May 13; 110(10):2479-88.
    View in: PubMed
    Score: 0.151
  12. Genome-wide functional screening identifies CDC37 as a crucial HSP90-cofactor for KIT oncogenic expression in gastrointestinal stromal tumors. Oncogene. 2014 Apr 03; 33(14):1872-6.
    View in: PubMed
    Score: 0.141
  13. 14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma. Proc Natl Acad Sci U S A. 2012 Jan 17; 109(3):929-34.
    View in: PubMed
    Score: 0.129
  14. KIT oncoprotein interactions in gastrointestinal stromal tumors: therapeutic relevance. Oncogene. 2007 Sep 27; 26(44):6386-95.
    View in: PubMed
    Score: 0.093
  15. Molecular correlates of imatinib resistance in gastrointestinal stromal tumors. J Clin Oncol. 2006 Oct 10; 24(29):4764-74.
    View in: PubMed
    Score: 0.089
  16. Targeting SALL4 by entinostat in lung cancer. Oncotarget. 2016 Nov 15; 7(46):75425-75440.
    View in: PubMed
    Score: 0.045
  17. The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor. Am J Surg Pathol. 2012 May; 36(5):641-53.
    View in: PubMed
    Score: 0.033
  18. Aberrant AKT activation drives well-differentiated liposarcoma. Proc Natl Acad Sci U S A. 2011 Sep 27; 108(39):16386-91.
    View in: PubMed
    Score: 0.032
  19. ALK rearrangement in sickle cell trait-associated renal medullary carcinoma. Genes Chromosomes Cancer. 2011 Mar; 50(3):146-53.
    View in: PubMed
    Score: 0.030
  20. Carbonic anhydrase II. A novel biomarker for gastrointestinal stromal tumors. Mod Pathol. 2010 May; 23(5):743-50.
    View in: PubMed
    Score: 0.028
  21. Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor. J Clin Oncol. 2008 Nov 20; 26(33):5352-9.
    View in: PubMed
    Score: 0.026
  22. Gastrointestinal stromal tumours overexpress fatty acid synthase. J Pathol. 2006 Jul; 209(3):369-75.
    View in: PubMed
    Score: 0.022
  23. Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profiles. Oncogene. 2004 Oct 14; 23(47):7780-90.
    View in: PubMed
    Score: 0.020
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.