Jacob Joseph, M.B.,B.S., M.D.
Associate Professor of Medicine
Brigham and Women's Hospital
Brigham and Women
Cardiovascular Division , NRB 630
77 Avenue Louis Pasteur
Boston MA 02115
Available: 09/04/18, Expires: 06/30/20
Use the Million Veteran Program cohort to analyze the impact of genetic variants in the risk and prognosis of heart failure
Student can contribute to genetic analysis and presentation/publication
Work will be performed at Veterans Affairs Boston Healthcare System
The research activities and funding listed below are automatically derived from
NIH ExPORTER and other sources, which might result in incorrect or missing items.
to make corrections and additions.
(ALEXANDER, KAREN P)
Sep 30, 2019 - Aug 31, 2026
PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr Adults (PREVENTABLE)
Role Description: The goal of PREVENTABLE is to generate knowledge about the role of statins in older adults, a population in which risk/benefit for primary prevention has been under studied.
Role: Co-PI of Clinical Sites Core and PI of VA Network
Jul 1, 2019 - Jun 30, 2023
Pragmatic Approaches to Capture and Ascertainment of Clinical Trial Endpoints
Role Description: The aim of this project is to develop methods to capture clinical trial endpoints from electronic medical records( EMR) and compare EMR based capture to traditional methods of endpoint capture and ascertainment
Role: Principal Investigator
(PHILLIPS, LAWRENCE S)
Oct 1, 2018 - Sep 30, 2020
Diabetic Complications and Genetic Variants in the Million Veterans Program
Role Description: The project targets discovery of new genetic variants that should help to improve the healthcare of adults with diabetes. The effects of genetic variants on the risk of incident heart failure with preserved and reduced ejection fraction and on outcomes in heart failure will be examined in the context of diabetes as a risk factor.
Role: Co-Investigator and lead of Heart Failure Genomics
(SOLOMON, SCOTT DAVID)
Feb 15, 2016 - Jan 31, 2021
INfluenza Vaccine to Effectively Stop Cardio Thoracic Events and Decompensated heart failure (INVESTED)
Role Description: The goal of this study is to compare high dose influenza vaccine to standard dose vaccine in reducing the time to first composite of death or cardiopulmonary hospitalization. The aim of the national VA Consortium is to coordinate study participation of 34 VA sites. In this study, we will explore pragmatic approaches to clinical trial conduct such as enhancing site-based recruitment by providing lists of eligible subjects generated using the national VA database and centralized approaches to collection of clinical trial endpoints.
Role: Co-PI of VA Network
Apr 1, 2008 - Sep 30, 2011
Selenium, Glutathione Peroxidase-1, and Homocysteine-induced Cardiac Remodeling
Role: Principal Investigator
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