Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Nancy L. Kedersha, PH.D.

Title
Institution
Department
Address
Phone
Fax

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Panas MD, Kedersha N, Schulte T, Branca RM, Ivanov P, Anderson P. Phosphorylation of G3BP1-S149 does not influence stress granule assembly. J Cell Biol. 2019 Jun 06. PMID: 31171631.
    Citations:    
  2. Ivanov P, Kedersha N, Anderson P. Stress Granules and Processing Bodies in Translational Control. Cold Spring Harb Perspect Biol. 2019 May 01; 11(5). PMID: 30082464.
    Citations:    Fields:    
  3. Rayman JB, Hijazi J, Li X, Kedersha N, Anderson PJ, Kandel ER. Genetic Perturbation of TIA1 Reveals a Physiological Role in Fear Memory. Cell Rep. 2019 Mar 12; 26(11):2970-2983.e4. PMID: 30865887.
    Citations:    
  4. Aulas A, Fay MM, Szaflarski W, Kedersha N, Anderson P, Ivanov P. Methods to Classify Cytoplasmic Foci as Mammalian Stress Granules. J Vis Exp. 2017 05 12; (123). PMID: 28570526.
    Citations: 3     Fields:    Translation:HumansCells
  5. Boeynaems S, Bogaert E, Kovacs D, Konijnenberg A, Timmerman E, Volkov A, Guharoy M, De Decker M, Jaspers T, Ryan VH, Janke AM, Baatsen P, Vercruysse T, Kolaitis RM, Daelemans D, Taylor JP, Kedersha N, Anderson P, Impens F, Sobott F, Schymkowitz J, Rousseau F, Fawzi NL, Robberecht W, Van Damme P, Tompa P, Van Den Bosch L. Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics. Mol Cell. 2017 Mar 16; 65(6):1044-1055.e5. PMID: 28306503.
    Citations: 27     Fields:    Translation:HumansCells
  6. Aulas A, Fay MM, Lyons SM, Achorn CA, Kedersha N, Anderson P, Ivanov P. Stress-specific differences in assembly and composition of stress granules and related foci. J Cell Sci. 2017 03 01; 130(5):927-937. PMID: 28096475.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  7. Nelson EV, Schmidt KM, Deflubé LR, Doganay S, Banadyga L, Olejnik J, Hume AJ, Ryabchikova E, Ebihara H, Kedersha N, Ha T, Mühlberger E. Ebola Virus Does Not Induce Stress Granule Formation during Infection and Sequesters Stress Granule Proteins within Viral Inclusions. J Virol. 2016 08 15; 90(16):7268-7284. PMID: 27252530.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  8. Lastres-Becker I, Nonis D, Eich F, Klinkenberg M, Gorospe M, Kötter P, Klein FA, Kedersha N, Auburger G. Mammalian ataxin-2 modulates translation control at the pre-initiation complex via PI3K/mTOR and is induced by starvation. Biochim Biophys Acta. 2016 09; 1862(9):1558-69. PMID: 27240544.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  9. Szaflarski W, Fay MM, Kedersha N, Zabel M, Anderson P, Ivanov P. Vinca alkaloid drugs promote stress-induced translational repression and stress granule formation. Oncotarget. 2016 May 24; 7(21):30307-22. PMID: 27083003.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  10. Lyons SM, Achorn C, Kedersha NL, Anderson PJ, Ivanov P. YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression. Nucleic Acids Res. 2016 08 19; 44(14):6949-60. PMID: 27174937.
    Citations: 17     Fields:    Translation:HumansCells
  11. Kedersha N, Panas MD, Achorn CA, Lyons S, Tisdale S, Hickman T, Thomas M, Lieberman J, McInerney GM, Ivanov P, Anderson P. G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits. J Cell Biol. 2016 Mar 28; 212(7):845-60. PMID: 27022092.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  12. Panas MD, Kedersha N, McInerney GM. Methods for the characterization of stress granules in virus infected cells. Methods. 2015 Nov 15; 90:57-64. PMID: 25896634.
    Citations: 11     Fields:    
  13. Reineke LC, Kedersha N, Langereis MA, van Kuppeveld FJ, Lloyd RE. Stress granules regulate double-stranded RNA-dependent protein kinase activation through a complex containing G3BP1 and Caprin1. MBio. 2015 Mar 17; 6(2):e02486. PMID: 25784705.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  14. Panas MD, Schulte T, Thaa B, Sandalova T, Kedersha N, Achour A, McInerney GM. Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation. PLoS Pathog. 2015 Feb; 11(2):e1004659. PMID: 25658430.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  15. Anderson P, Kedersha N, Ivanov P. Stress granules, P-bodies and cancer. Biochim Biophys Acta. 2015 Jul; 1849(7):861-70. PMID: 25482014.
    Citations: 56     Fields:    Translation:HumansAnimalsCells
  16. Heck MV, Azizov M, Stehning T, Walter M, Kedersha N, Auburger G. Dysregulated expression of lipid storage and membrane dynamics factors in Tia1 knockout mouse nervous tissue. Neurogenetics. 2014 May; 15(2):135-44. PMID: 24659297.
    Citations: 13     Fields:    Translation:AnimalsCells
  17. Rozelle DK, Filone CM, Kedersha N, Connor JH. Activation of stress response pathways promotes formation of antiviral granules and restricts virus replication. Mol Cell Biol. 2014 Jun; 34(11):2003-16. PMID: 24662051.
    Citations: 8     Fields:    Translation:HumansCells
  18. Kedersha N, Ivanov P, Anderson P. Stress granules and cell signaling: more than just a passing phase? Trends Biochem Sci. 2013 Oct; 38(10):494-506. PMID: 24029419.
    Citations: 120     Fields:    Translation:HumansAnimalsCells
  19. Stoecklin G, Kedersha N. Relationship of GW/P-bodies with stress granules. Adv Exp Med Biol. 2013; 768:197-211. PMID: 23224972.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  20. Ivanov P, Kedersha N, Anderson P. Stress puts TIA on TOP. Genes Dev. 2011 Oct 15; 25(20):2119-24. PMID: 22012617.
    Citations: 16     Fields:    Translation:HumansCells
  21. Shih JD, Waks Z, Kedersha N, Silver PA. Visualization of single mRNAs reveals temporal association of proteins with microRNA-regulated mRNA. Nucleic Acids Res. 2011 Sep 01; 39(17):7740-9. PMID: 21653551.
    Citations: 11     Fields:    Translation:HumansCells
  22. Simpson-Holley M, Kedersha N, Dower K, Rubins KH, Anderson P, Hensley LE, Connor JH. Formation of antiviral cytoplasmic granules during orthopoxvirus infection. J Virol. 2011 Feb; 85(4):1581-93. PMID: 21147913.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  23. Simarro M, Gimenez-Cassina A, Kedersha N, Lazaro JB, Adelmant GO, Marto JA, Rhee K, Tisdale S, Danial N, Benarafa C, Orduña A, Anderson P. Fast kinase domain-containing protein 3 is a mitochondrial protein essential for cellular respiration. Biochem Biophys Res Commun. 2010 Oct 22; 401(3):440-6. PMID: 20869947.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  24. Emara MM, Ivanov P, Hickman T, Dawra N, Tisdale S, Kedersha N, Hu GF, Anderson P. Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly. J Biol Chem. 2010 Apr 02; 285(14):10959-68. PMID: 20129916.
    Citations: 139     Fields:    Translation:HumansCells
  25. Kedersha N, Anderson P. Regulation of translation by stress granules and processing bodies. Prog Mol Biol Transl Sci. 2009; 90:155-85. PMID: 20374741.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  26. Farny NG, Kedersha NL, Silver PA. Metazoan stress granule assembly is mediated by P-eIF2alpha-dependent and -independent mechanisms. RNA. 2009 Oct; 15(10):1814-21. PMID: 19661161.
    Citations: 33     Fields:    Translation:AnimalsCells
  27. Anderson P, Kedersha N. RNA granules: post-transcriptional and epigenetic modulators of gene expression. Nat Rev Mol Cell Biol. 2009 Jun; 10(6):430-6. PMID: 19461665.
    Citations: 265     Fields:    Translation:AnimalsCells
  28. Anderson P, Kedersha N. Stress granules. Curr Biol. 2009 May 26; 19(10):R397-8. PMID: 19467203.
    Citations: 83     Fields:    Translation:HumansAnimalsCells
  29. Otsuka Y, Kedersha NL, Schoenberg DR. Identification of a cytoplasmic complex that adds a cap onto 5'-monophosphate RNA. Mol Cell Biol. 2009 Apr; 29(8):2155-67. PMID: 19223470.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  30. Ohn T, Kedersha N, Hickman T, Tisdale S, Anderson P. A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly. Nat Cell Biol. 2008 Oct; 10(10):1224-31. PMID: 18794846.
    Citations: 133     Fields:    Translation:HumansAnimalsCells
  31. Jimenez-Boj E, Kedersha N, Tohidast-Akrad M, Karlhofer FM, Stummvoll G, Zimmermann C, Ulrich W, Guiducci S, Hoefler E, Aringer M, Schett G, Matucci-Cerinic M, Smolen JS, Steiner G. Autoantibodies to the translational suppressors T cell intracytoplasmic antigen 1 and T cell intracytoplasmic antigen 1-related protein in patients with rheumatic diseases: increased prevalence in systemic lupus erythematosus and systemic sclerosis and correlation with clinical features. Arthritis Rheum. 2008 May; 58(5):1226-36. PMID: 18438838.
    Citations: 2     Fields:    Translation:Humans
  32. Anderson P, Kedersha N. Stress granules: the Tao of RNA triage. Trends Biochem Sci. 2008 Mar; 33(3):141-50. PMID: 18291657.
    Citations: 390     Fields:    Translation:HumansAnimalsCells
  33. Kedersha N, Tisdale S, Hickman T, Anderson P. Real-time and quantitative imaging of mammalian stress granules and processing bodies. Methods Enzymol. 2008; 448:521-52. PMID: 19111193.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  34. Yamasaki S, Stoecklin G, Kedersha N, Simarro M, Anderson P. T-cell intracellular antigen-1 (TIA-1)-induced translational silencing promotes the decay of selected mRNAs. J Biol Chem. 2007 Oct 12; 282(41):30070-7. PMID: 17711853.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  35. Kim HS, Kuwano Y, Zhan M, Pullmann R, Mazan-Mamczarz K, Li H, Kedersha N, Anderson P, Wilce MC, Gorospe M, Wilce JA. Elucidation of a C-rich signature motif in target mRNAs of RNA-binding protein TIAR. Mol Cell Biol. 2007 Oct; 27(19):6806-17. PMID: 17682065.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  36. Sivan G, Kedersha N, Elroy-Stein O. Ribosomal slowdown mediates translational arrest during cellular division. Mol Cell Biol. 2007 Oct; 27(19):6639-46. PMID: 17664278.
    Citations: 51     Fields:    Translation:HumansAnimalsCells
  37. Simarro M, Mauger D, Rhee K, Pujana MA, Kedersha NL, Yamasaki S, Cusick ME, Vidal M, Garcia-Blanco MA, Anderson P. Fas-activated serine/threonine phosphoprotein (FAST) is a regulator of alternative splicing. Proc Natl Acad Sci U S A. 2007 Jul 03; 104(27):11370-5. PMID: 17592127.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  38. Anderson P, Kedersha N. On again, off again: the SRC-3 transcriptional coactivator moonlights as a translational corepressor. Mol Cell. 2007 Mar 23; 25(6):796-7. PMID: 17386257.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  39. Kedersha N, Anderson P. Mammalian stress granules and processing bodies. Methods Enzymol. 2007; 431:61-81. PMID: 17923231.
    Citations: 233     Fields:    Translation:HumansAnimalsCells
  40. Yang F, Peng Y, Murray EL, Otsuka Y, Kedersha N, Schoenberg DR. Polysome-bound endonuclease PMR1 is targeted to stress granules via stress-specific binding to TIA-1. Mol Cell Biol. 2006 Dec; 26(23):8803-13. PMID: 16982678.
    Citations: 18     Fields:    Translation:AnimalsCells
  41. Dang Y, Kedersha N, Low WK, Romo D, Gorospe M, Kaufman R, Anderson P, Liu JO. Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A. J Biol Chem. 2006 Oct 27; 281(43):32870-8. PMID: 16951406.
    Citations: 106     Fields:    Translation:HumansAnimalsCells
  42. Anderson P, Kedersha N. RNA granules. J Cell Biol. 2006 Mar 13; 172(6):803-8. PMID: 16520386.
    Citations: 364     Fields:    Translation:HumansAnimalsCells
  43. Kedersha N, Stoecklin G, Ayodele M, Yacono P, Lykke-Andersen J, Fritzler MJ, Scheuner D, Kaufman RJ, Golan DE, Anderson P. Stress granules and processing bodies are dynamically linked sites of mRNP remodeling. J Cell Biol. 2005 Jun 20; 169(6):871-84. PMID: 15967811.
    Citations: 465     Fields:    Translation:HumansAnimalsCells
  44. McInerney GM, Kedersha NL, Kaufman RJ, Anderson P, Liljeström P. Importance of eIF2alpha phosphorylation and stress granule assembly in alphavirus translation regulation. Mol Biol Cell. 2005 Aug; 16(8):3753-63. PMID: 15930128.
    Citations: 94     Fields:    Translation:AnimalsCells
  45. McEwen E, Kedersha N, Song B, Scheuner D, Gilks N, Han A, Chen JJ, Anderson P, Kaufman RJ. Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates survival upon arsenite exposure. J Biol Chem. 2005 Apr 29; 280(17):16925-33. PMID: 15684421.
    Citations: 125     Fields:    Translation:AnimalsCells
  46. Loughran G, Healy NC, Kiely PA, Huigsloot M, Kedersha NL, O'Connor R. Mystique is a new insulin-like growth factor-I-regulated PDZ-LIM domain protein that promotes cell attachment and migration and suppresses Anchorage-independent growth. Mol Biol Cell. 2005 Apr; 16(4):1811-22. PMID: 15659642.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  47. Li W, Simarro M, Kedersha N, Anderson P. FAST is a survival protein that senses mitochondrial stress and modulates TIA-1-regulated changes in protein expression. Mol Cell Biol. 2004 Dec; 24(24):10718-32. PMID: 15572676.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  48. Gilks N, Kedersha N, Ayodele M, Shen L, Stoecklin G, Dember LM, Anderson P. Stress granule assembly is mediated by prion-like aggregation of TIA-1. Mol Biol Cell. 2004 Dec; 15(12):5383-98. PMID: 15371533.
    Citations: 314     Fields:    Translation:HumansAnimalsCells
  49. Li W, Kedersha N, Chen S, Gilks N, Lee G, Anderson P. FAST is a BCL-X(L)-associated mitochondrial protein. Biochem Biophys Res Commun. 2004 May 21; 318(1):95-102. PMID: 15110758.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  50. Anderson P, Phillips K, Stoecklin G, Kedersha N. Post-transcriptional regulation of proinflammatory proteins. J Leukoc Biol. 2004 Jul; 76(1):42-7. PMID: 15075353.
    Citations: 45     Fields:    Translation:HumansAnimalsCells
  51. Stoecklin G, Stubbs T, Kedersha N, Wax S, Rigby WF, Blackwell TK, Anderson P. MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay. EMBO J. 2004 Mar 24; 23(6):1313-24. PMID: 15014438.
    Citations: 206     Fields:    Translation:HumansAnimalsCells
  52. Phillips K, Kedersha N, Shen L, Blackshear PJ, Anderson P. Arthritis suppressor genes TIA-1 and TTP dampen the expression of tumor necrosis factor alpha, cyclooxygenase 2, and inflammatory arthritis. Proc Natl Acad Sci U S A. 2004 Feb 17; 101(7):2011-6. PMID: 14769925.
    Citations: 67     Fields:    Translation:AnimalsCells
  53. Eichenmüller B, Kedersha N, Solovyeva E, Everley P, Lang J, Himes RH, Suprenant KA. Vaults bind directly to microtubules via their caps and not their barrels. Cell Motil Cytoskeleton. 2003 Dec; 56(4):225-36. PMID: 14584025.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  54. Ida H, Nakashima T, Kedersha NL, Yamasaki S, Huang M, Izumi Y, Miyashita T, Origuchi T, Kawakami A, Migita K, Bird PI, Anderson P, Eguchi K. Granzyme B leakage-induced cell death: a new type of activation-induced natural killer cell death. Eur J Immunol. 2003 Dec; 33(12):3284-92. PMID: 14635036.
    Citations: 16     Fields:    Translation:HumansCells
  55. Zhu H, Hasman RA, Young KM, Kedersha NL, Lou H. U1 snRNP-dependent function of TIAR in the regulation of alternative RNA processing of the human calcitonin/CGRP pre-mRNA. Mol Cell Biol. 2003 Sep; 23(17):5959-71. PMID: 12917321.
    Citations: 32     Fields:    Translation:HumansCells
  56. Dixon DA, Balch GC, Kedersha N, Anderson P, Zimmerman GA, Beauchamp RD, Prescott SM. Regulation of cyclooxygenase-2 expression by the translational silencer TIA-1. J Exp Med. 2003 Aug 04; 198(3):475-81. PMID: 12885872.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  57. Li W, Li Y, Kedersha N, Anderson P, Emara M, Swiderek KM, Moreno GT, Brinton MA. Cell proteins TIA-1 and TIAR interact with the 3' stem-loop of the West Nile virus complementary minus-strand RNA and facilitate virus replication. J Virol. 2002 Dec; 76(23):11989-2000. PMID: 12414941.
    Citations: 78     Fields:    Translation:AnimalsCells
  58. Kedersha N, Anderson P. Stress granules: sites of mRNA triage that regulate mRNA stability and translatability. Biochem Soc Trans. 2002 Nov; 30(Pt 6):963-9. PMID: 12440955.
    Citations: 239     Fields:    Translation:HumansAnimalsCells
  59. Iseni F, Garcin D, Nishio M, Kedersha N, Anderson P, Kolakofsky D. Sendai virus trailer RNA binds TIAR, a cellular protein involved in virus-induced apoptosis. EMBO J. 2002 Oct 01; 21(19):5141-50. PMID: 12356730.
    Citations: 45     Fields:    Translation:HumansCells
  60. Anderson P, Kedersha N. Stressful initiations. J Cell Sci. 2002 Aug 15; 115(Pt 16):3227-34. PMID: 12140254.
    Citations: 130     Fields:    Translation:Cells
  61. Anderson P, Kedersha N. Visibly stressed: the role of eIF2, TIA-1, and stress granules in protein translation. Cell Stress Chaperones. 2002 Apr; 7(2):213-21. PMID: 12380690.
    Citations: 103     Fields:    Translation:HumansCells
  62. Kedersha N, Chen S, Gilks N, Li W, Miller IJ, Stahl J, Anderson P. Evidence that ternary complex (eIF2-GTP-tRNA(i)(Met))-deficient preinitiation complexes are core constituents of mammalian stress granules. Mol Biol Cell. 2002 Jan; 13(1):195-210. PMID: 11809833.
    Citations: 184     Fields:    Translation:HumansAnimalsCells
  63. Hayajneh WA, Colberg-Poley AM, Skaletskaya A, Bartle LM, Lesperance MM, Contopoulos-Ioannidis DG, Kedersha NL, Goldmacher VS. The sequence and antiapoptotic functional domains of the human cytomegalovirus UL37 exon 1 immediate early protein are conserved in multiple primary strains. Virology. 2001 Jan 05; 279(1):233-40. PMID: 11145905.
    Citations: 32     Fields:    Translation:HumansCells
  64. Kedersha N, Cho MR, Li W, Yacono PW, Chen S, Gilks N, Golan DE, Anderson P. Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules. J Cell Biol. 2000 Dec 11; 151(6):1257-68. PMID: 11121440.
    Citations: 253     Fields:    Translation:AnimalsCells
  65. Förch P, Puig O, Kedersha N, Martínez C, Granneman S, Séraphin B, Anderson P, Valcárcel J. The apoptosis-promoting factor TIA-1 is a regulator of alternative pre-mRNA splicing. Mol Cell. 2000 Nov; 6(5):1089-98. PMID: 11106748.
    Citations: 109     Fields:    Translation:HumansAnimalsCells
  66. Piecyk M, Wax S, Beck AR, Kedersha N, Gupta M, Maritim B, Chen S, Gueydan C, Kruys V, Streuli M, Anderson P. TIA-1 is a translational silencer that selectively regulates the expression of TNF-alpha. EMBO J. 2000 Aug 01; 19(15):4154-63. PMID: 10921895.
    Citations: 180     Fields:    Translation:AnimalsCells
  67. Kleijnen MF, Shih AH, Zhou P, Kumar S, Soccio RE, Kedersha NL, Gill G, Howley PM. The hPLIC proteins may provide a link between the ubiquitination machinery and the proteasome. Mol Cell. 2000 Aug; 6(2):409-19. PMID: 10983987.
    Citations: 133     Fields:    Translation:HumansAnimalsCells
  68. Kedersha NL, Gupta M, Li W, Miller I, Anderson P. RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules. J Cell Biol. 1999 Dec 27; 147(7):1431-42. PMID: 10613902.
    Citations: 371     Fields:    Translation:HumansAnimalsCells
  69. Goldmacher VS, Bartle LM, Skaletskaya A, Dionne CA, Kedersha NL, Vater CA, Han JW, Lutz RJ, Watanabe S, Cahir McFarland ED, Kieff ED, Mocarski ES, Chittenden T. A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12536-41. PMID: 10535957.
    Citations: 151     Fields:    Translation:HumansCells
  70. Kickhoefer VA, Siva AC, Kedersha NL, Inman EM, Ruland C, Streuli M, Rome LH. The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase. J Cell Biol. 1999 Sep 06; 146(5):917-28. PMID: 10477748.
    Citations: 75     Fields:    Translation:HumansAnimalsCells
  71. Seipel K, Medley QG, Kedersha NL, Zhang XA, O'Brien SP, Serra-Pages C, Hemler ME, Streuli M. Trio amino-terminal guanine nucleotide exchange factor domain expression promotes actin cytoskeleton reorganization, cell migration and anchorage-independent cell growth. J Cell Sci. 1999 Jun; 112 ( Pt 12):1825-34. PMID: 10341202.
    Citations: 21     Fields:    Translation:AnimalsCells
  72. Calautti E, Cabodi S, Stein PL, Hatzfeld M, Kedersha N, Paolo Dotto G. Tyrosine phosphorylation and src family kinases control keratinocyte cell-cell adhesion. J Cell Biol. 1998 Jun 15; 141(6):1449-65. PMID: 9628900.
    Citations: 65     Fields:    Translation:AnimalsCells
  73. Ladino CA, Chari RV, Bourret LA, Kedersha NL, Goldmacher VS. Folate-maytansinoids: target-selective drugs of low molecular weight. Int J Cancer. 1997 Dec 10; 73(6):859-64. PMID: 9399666.
    Citations: 10     Fields:    Translation:HumansCells
  74. Han JW, Dionne CA, Kedersha NL, Goldmacher VS. p53 status affects the rate of the onset but not the overall extent of doxorubicin-induced cell death in rat-1 fibroblasts constitutively expressing c-Myc. Cancer Res. 1997 Jan 01; 57(1):176-82. PMID: 8988061.
    Citations: 9     Fields:    Translation:AnimalsCells
  75. Liu C, Tadayoni BM, Bourret LA, Mattocks KM, Derr SM, Widdison WC, Kedersha NL, Ariniello PD, Goldmacher VS, Lambert JM, Blättler WA, Chari RV. Eradication of large colon tumor xenografts by targeted delivery of maytansinoids. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8618-23. PMID: 8710920.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  76. Martersteck CM, Kedersha NL, Drapp DA, Tsui TG, Colley KJ. Unique alpha 2, 8-polysialylated glycoproteins in breast cancer and leukemia cells. Glycobiology. 1996 Apr; 6(3):289-301. PMID: 8724137.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  77. Medley QG, Kedersha N, O'Brien S, Tian Q, Schlossman SF, Streuli M, Anderson P. Characterization of GMP-17, a granule membrane protein that moves to the plasma membrane of natural killer cells following target cell recognition. Proc Natl Acad Sci U S A. 1996 Jan 23; 93(2):685-9. PMID: 8570616.
    Citations: 19     Fields:    Translation:AnimalsCells
  78. Serra-Pagès C, Kedersha NL, Fazikas L, Medley Q, Debant A, Streuli M. The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions. EMBO J. 1995 Jun 15; 14(12):2827-38. PMID: 7796809.
    Citations: 77     Fields:    Translation:HumansCells
  79. Taupin JL, Tian Q, Kedersha N, Robertson M, Anderson P. The RNA-binding protein TIAR is translocated from the nucleus to the cytoplasm during Fas-mediated apoptotic cell death. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1629-33. PMID: 7533298.
    Citations: 40     Fields:    Translation:HumansCells
  80. Chugani DC, Rome LH, Kedersha NL. Evidence that vault ribonucleoprotein particles localize to the nuclear pore complex. J Cell Sci. 1993 Sep; 106 ( Pt 1):23-9. PMID: 8270627.
    Citations: 39     Fields:    Translation:AnimalsCells
  81. Vasu SK, Kedersha NL, Rome LH. cDNA cloning and disruption of the major vault protein alpha gene (mvpA) in Dictyostelium discoideum. J Biol Chem. 1993 Jul 25; 268(21):15356-60. PMID: 8340365.
    Citations: 9     Fields:    Translation:AnimalsCells
  82. Goguen B, Kedersha N. Clonogenic cytotoxicity testing by microdrop encapsulation. Nature. 1993 May 13; 363(6425):189-90. PMID: 8483506.
    Citations: 1     Fields:    Translation:Cells
  83. Kickhoefer VA, Searles RP, Kedersha NL, Garber ME, Johnson DL, Rome LH. Vault ribonucleoprotein particles from rat and bullfrog contain a related small RNA that is transcribed by RNA polymerase III. J Biol Chem. 1993 Apr 15; 268(11):7868-73. PMID: 7681830.
    Citations: 27     Fields:    Translation:AnimalsCells
  84. Rome L, Kedersha N, Chugani D. Unlocking vaults: organelles in search of a function. Trends Cell Biol. 1991 Aug; 1(2-3):47-50. PMID: 14731565.
    Citations: 19     Fields:    
  85. Chugani DC, Kedersha NL, Rome LH. Vault immunofluorescence in the brain: new insights regarding the origin of microglia. J Neurosci. 1991 Jan; 11(1):256-68. PMID: 1986066.
    Citations: 13     Fields:    Translation:AnimalsCells
  86. Kedersha NL, Heuser JE, Chugani DC, Rome LH. Vaults. III. Vault ribonucleoprotein particles open into flower-like structures with octagonal symmetry. J Cell Biol. 1991 Jan; 112(2):225-35. PMID: 1988458.
    Citations: 51     Fields:    Translation:Animals
  87. Kedersha NL, Miquel MC, Bittner D, Rome LH. Vaults. II. Ribonucleoprotein structures are highly conserved among higher and lower eukaryotes. J Cell Biol. 1990 Apr; 110(4):895-901. PMID: 1691193.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  88. Kedersha NL, Rome LH. Vaults: large cytoplasmic RNP's that associate with cytoskeletal elements. Mol Biol Rep. 1990; 14(2-3):121-2. PMID: 1694556.
    Citations: 7     Fields:    Translation:AnimalsCells
  89. Bassuk JA, Kao WW, Herzer P, Kedersha NL, Seyer J, DeMartino JA, Daugherty BL, Mark GE, Berg RA. Prolyl 4-hydroxylase: molecular cloning and the primary structure of the alpha subunit from chicken embryo. Proc Natl Acad Sci U S A. 1989 Oct; 86(19):7382-6. PMID: 2552442.
    Citations: 14     Fields:    Translation:AnimalsCells
  90. Lemansky P, Hasilik A, von Figura K, Helmy S, Fishman J, Fine RE, Kedersha NL, Rome LH. Lysosomal enzyme precursors in coated vesicles derived from the exocytic and endocytic pathways. J Cell Biol. 1987 Jun; 104(6):1743-8. PMID: 2884223.
    Citations: 15     Fields:    Translation:AnimalsCells
  91. Kedersha NL, Rome LH. Isolation and characterization of a novel ribonucleoprotein particle: large structures contain a single species of small RNA. J Cell Biol. 1986 Sep; 103(3):699-709. PMID: 2943744.
    Citations: 67     Fields:    Translation:AnimalsCells
  92. Kedersha NL, Broek D, Berg RA. A novel isoform of cytoplasmic actin that binds poly-L-proline. Biochem J. 1986 Sep 01; 238(2):561-70. PMID: 3541913.
    Citations: 1     Fields:    Translation:AnimalsCells
  93. Kedersha NL, Hill DF, Kronquist KE, Rome LH. Subpopulations of liver coated vesicles resolved by preparative agarose gel electrophoresis. J Cell Biol. 1986 Jul; 103(1):287-97. PMID: 2941442.
    Citations: 5     Fields:    Translation:AnimalsCells
  94. Kedersha NL, Rome LH. Preparative agarose gel electrophoresis for the purification of small organelles and particles. Anal Biochem. 1986 Jul; 156(1):161-70. PMID: 2426986.
    Citations: 8     Fields:    Translation:Animals
  95. Kedersha NL, Tkacz JS, Berg RA. Biosynthesis of prolyl hydroxylase: evidence for two separate dolichol-media pathways of glycosylation. Biochemistry. 1985 Oct 08; 24(21):5960-7. PMID: 3002430.
    Citations: 4     Fields:    Translation:Animals
  96. Kedersha NL, Tkacz JS, Berg RA. Characterization of the oligosaccharides of prolyl hydroxylase, a microsomal glycoprotein. Biochemistry. 1985 Oct 08; 24(21):5952-60. PMID: 3002429.
    Citations: 7     Fields:    Translation:AnimalsCells
  97. Kedersha NL, Berg RA. An improved method for the purification of vertebrate prolyl hydroxylase by affinity chromatography. Coll Relat Res. 1981 Jul; 1(4):345-53. PMID: 6286234.
    Citations: 13     Fields:    Translation:Animals
  98. Berg RA, Kao WW, Kedersha NL. The assembly of tetrameric prolyl hydroxylase in tendon fibroblasts from newly synthesized alpha-subunits and from preformed cross-reacting protein. Biochem J. 1980 Sep 01; 189(3):491-9. PMID: 6260081.
    Citations: 7     Fields:    Translation:AnimalsCells
  99. Berg RA, Kedersha NL, Guzman NA. Purification and partial characterization of the two nonidentical subunits of prolyl hydroxylase. J Biol Chem. 1979 Apr 25; 254(8):3111-8. PMID: 218963.
    Citations: 8     Fields:    Translation:Animals
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Kedersha's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (489)
Explore
_
Co-Authors (18)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.