Title Peter C. Farrell Professor of Sleep Medicine Institution Brigham and Women's Hospital Address Brigham and Womens Hospital Sleep Medicine - BLI 438 221 Longwood Ave Boston MA 02115
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Title
Professor in the Department of Epidemiology
Institution
Harvard T.H. Chan School of Public Health

Biography
Boston University, Boston | BA | 05/1979 | Six Year Medical Honors Program |
Boston University School of Medicine, Boston | MD | 05/1979 | Medicine |
Harvard School Of Public Health, Boston | MPH | 05/1986 | Respiratory Epidemiology |
2017
William C Dement Scientific Achievement Award
2012
Scientific Recognition Award
2008
Association of American Physicians
2008
Sleep In Infancy and Childhood Award
2007
Spotlight on Women's Scholarship

Overview
I direct the Program in Sleep Medicine Epidemiology at BWH. Our goals are to conduct rigorous and population-based research to: elucidate the role of genetics, early life developmental factors, and environmental exposures on sleep health; identify how social and environmental factors shape sleep health disparities which in turn drive chronic health disparities; and identify the role of sleep interventions in improving health, including cardiovascular, metabolic, and cognitive disorders.
Within the Program, we support the following Resources:
The BWH Sleep Reading Center (www.bostonsleep.org), an international core laboratory that provides leadership in the design and implementation of sleep data collection for numerous clinical trials and cohort studies. It spearheaded efforts at establishing rigorous quality control procedures for multi-site sleep research and for integrating advanced signal processing analytics into large scale-epidemiological datasets to provide quantitative biomarkers of sleep and sleep disorders.
The National Sleep Research Resource (NSRR; www.sleepdata.org), a NHLBI-data and tool repository and community engagement resource that shares large quantities of polysomnography, actigraphy and other data coupled with tools to structure, harmonize, visualize and analyze sleep data.
The Sleep Apnea Patient-Centered Outcomes Network (MyApnea; www.myapnea.org), a web-based portal to promote sleep apnea patient support and patient engagement in research.
I am the recipient of a NHLBI Outstanding Investigator Award (R35) that supports a research and training program, Phenotypic and Genomic Signatures For Sleep Apnea. This program brings together trainees and experts in epidemiology, genetic and sleep/respiratory physiology to identify biomarkers and molecular mechanisms for sleep apnea risk, models interactions between sleep disorders and genetic risk factors (G*E), and attempts to resolve the heterogeneity in sleep apnea that predicts differences in outcomes and treatment response.
I co-direct the following multi-center clinical trials:
Pediatric Adenotonsillectomy Trial (PATS; patstrial.org)
Impact of Low Flow Oxygen on Hospital Admissions and Mortality in Heart Failure and Central Sleep Apnea (LOFT-HF; lofthf.study).
I co-lead a cohort study examining the impact of the home environment on sleep disorders among children in low income urban neighborhoods. (Environmental Assessment of Sleep in Youth).

Research
The research activities and funding listed below are automatically derived from
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R01AG070867
(PURCELL, SHAUN M;REDLINE, SUSAN S.)
May 1, 2021 - Feb 28, 2025
Longitudinal Relationships Among Sleep, Cognition and Alzheimer's Disease Biomarkers: Discerning Causal Associations, Mediators and Susceptibility
Role: Principal Investigator
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U24HL140412
(REDLINE, SUSAN S.)
Aug 1, 2018 - Jul 31, 2024
Impact of Low Flow Nocturnal Oxygen Therapy On Hospital Admissions and Mortality in Patients with Heart Failure and Central Sleep Apnea - DCC
Role: Principal Investigator
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R35HL135818
(REDLINE, SUSAN S.)
Jan 1, 2017 - Dec 31, 2023
Phenotypic and Molecular Signatures for Sleep Apnea and Related Morbidities
Role: Principal Investigator
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R01HL131049
(KUNISAKI, KEN M.)
Apr 1, 2016 - Mar 31, 2021
Sleep, Aging, and HIV Infection Cohort Study
Role: Co-Principal Investigator
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R01DK107972
(TAVERAS BENAVIDEZ, ELSIE MIREYA)
Sep 30, 2015 - Jul 31, 2021
Infant Sleep Patterns and Accelerated Growth Trajectories from Birth to 24 months
Role: Co-Principal Investigator
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U01HL125307
(REDLINE, SUSAN S.)
Sep 4, 2015 - Jun 30, 2021
Impact of treatment of mild sleep-disordered breathing on children's health-DCC
Role: Principal Investigator
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R01HL125307
(REDLINE, SUSAN S.)
Sep 4, 2015 - Jun 30, 2020
Impact of treatment of mild sleep-disordered breathing on children's health-DCC
Role: Principal Investigator
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R34AT008923
(REDLINE, SUSAN S.)
Sep 1, 2015 - Jun 30, 2019
Adapting Sleep and Yoga Interventions for Maximal Effectiveness in Low Income Populations
Role: Principal Investigator
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R24HL114473
(REDLINE, SUSAN S.)
Sep 5, 2013 - Oct 31, 2019
National Sleep Research Resource (NSRR)
Role: Principal Investigator
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R01HL113338
(REDLINE, SUSAN S.)
Sep 25, 2012 - Mar 31, 2019
Leveraging Family Data to Identify Genetic Variants for Sleep Apnea
Role: Co-Principal Investigator
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R01HL110068
(WILSON, JAMES GRAHAM)
Jun 1, 2012 - May 31, 2017
Sleep-Disordered Breathing and Risk for CVD and Stroke in the Jackson Heart Study
Role: Principal Investigator
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U34HL105277
(REDLINE, SUSAN S.)
Sep 20, 2010 - May 31, 2014
A Planning Study: Sleep Apnea Intervention for Cardiovascular Disease Reduction
Role: Co-Principal Investigator
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R01HL098433
(REDLINE, SUSAN S.)
Jul 5, 2010 - Apr 30, 2016
ASSOCIATION OF SLEEP DISORDERS WITH CARDIOVASCULAR HEALTH ACROSS ETHNIC GROUPS
Role: Principal Investigator
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RC2HL101417
(REDLINE, SUSAN S.)
Sep 30, 2009 - Aug 31, 2012
PHASE II TRIAL OF SLEEP APNEA TREATMENT TO REDUCE CARDIOVASCULAR MORBIDITY
Role: Principal Investigator
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U01HL083075
(REDLINE, SUSAN S.)
Sep 25, 2006 - Jul 31, 2013
Randomized Controlled Study of Adenotonsillectomy for Childhood Sleep Apnea
Role: Principal Investigator
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T35HL082544
(TOOSSI, ZAHRA TOOSSI)
Jun 1, 2006 - May 31, 2013
Research Training in Heart, Lung, Blood &Sleep Diseases
Role: Co-Principal Investigator
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U54CA116867
(BERGER, NATHAN A.)
Sep 1, 2005 - Aug 31, 2012
CASE Center for Transdisciplinary Research on Energetics and Cancer
Role: Co-Principal Investigator
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R01HL075077
(REDLINE, SUSAN S)
Sep 30, 2003 - Jul 31, 2008
Effects of Sleep Apnea Treatment on Metabolic Syndrome
Role: Principal Investigator
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R01HL070839
(REDLINE, SUSAN S)
Sep 1, 2003 - Jun 30, 2009
Outcomes of Sleep Disorders in Older Men- Reading Center
Role: Principal Investigator
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R01HL070916
(REDLINE, SUSAN S)
Sep 1, 2002 - Jul 31, 2008
Outcomes of Sleep Disordered Breathing In Adolescents
Role: Principal Investigator
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U01HL063463
(REDLINE, SUSAN S)
Sep 30, 1999 - Aug 31, 2010
The Sleep Heart Health Study
Role: Principal Investigator
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R01HL060957
(REDLINE, SUSAN S)
Jul 10, 1998 - Jun 30, 2002
EPIDEMIOLOGY OF SLEEP DISORDERED BREATHING IN CHILDREN
Role: Principal Investigator
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P41EB001978
(D'ARGENIO, DAVID Z)
Sep 30, 1997 - Aug 31, 2018
Biomedical Simulations Resource (BMSR)
Role: Co-Principal Investigator
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R01HL046380
(REDLINE, SUSAN S)
Aug 1, 1990 - Mar 31, 2008
Familial Aggregation and Natural History of Sleep Apnea
Role: Principal Investigator
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P50HL042215
(REDLINE, SUSAN S)
Sep 30, 1988 - Aug 31, 1999
NEUROPSYCHOLOGICAL DEFICITS IN SLEEP APNEA
Role: Principal Investigator
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P41RR003655
(ELSTON, ROBERT C.)
Sep 30, 1987 - Jul 31, 2012
Human Genetic Analysis Resource
Role: Co-Principal Investigator
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M01RR000080
(DAVIS, PAMELA B)
Dec 1, 1978 - Mar 31, 2009
General Clinical Research Center
Role: Co-Principal Investigator

Bibliographic
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