Harvard Catalyst Profiles

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Robert C. Flaumenhaft, M.D., Ph.D.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. U01HL143365 (ZWICKER, JEFFREY) Aug 1, 2018 - Jul 31, 2023
    NIH
    Biomarkers and mechanisms in cancer associated thrombosis
    Role: Co-Principal Investigator
  2. R13HL142275 (FLAUMENHAFT, ROBERT C) Jun 1, 2018 - May 31, 2019
    NIH
    FASEB SRC on Functional Disulfide Bonds in Health and Disease
    Role: Principal Investigator
  3. R35HL135775 (FLAUMENHAFT, ROBERT C) Feb 1, 2017 - Jan 31, 2024
    NIH
    Thiol Isomerases in Hemostasis and Thrombosis
    Role: Principal Investigator
  4. R01HL125275 (FLAUMENHAFT, ROBERT C) Sep 15, 2014 - May 31, 2020
    NIH
    Targeting the Endothelium in Sepsis
    Role: Principal Investigator
  5. R01HL112809 (FLAUMENHAFT, ROBERT C) Feb 1, 2013 - Jan 31, 2017
    NIH
    Platelet granule exocytosis and thrombus formation
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Roka-Moiia Y, Ammann K, Miller-Gutierrez S, Sheriff J, Bluestein D, Italiano JE, Flaumenhaft RC, Slepian MJ. Shear-Mediated Platelet Microparticles Demonstrate Phenotypic Heterogeneity as to Morphology, Receptor Distribution, and Hemostatic Function. bioRxiv. 2023 Feb 08. PMID: 36798322; PMCID: PMC9934663.
    Citations:    
  2. Flaumenhaft R. Platelets: out of shape and misbehaving. Blood. 2022 11 24; 140(21):2188-2190. PMID: 36422862.
    Citations:    Fields:    Translation:AnimalsCells
  3. Schwake C, McKay L, Griffiths A, Scartelli C, Flaumenhaft R, Chishti AH. BDA-410 inhibits SARS-CoV-2 main protease activity and viral replication in mammalian cells. J Cell Mol Med. 2022 10; 26(19):5095-5098. PMID: 36082511; PMCID: PMC9537889.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  4. Shieh M, Ni X, Xu S, Lindahl SP, Yang M, Matsunaga T, Flaumenhaft R, Akaike T, Xian M. Shining a light on SSP4: A comprehensive analysis and biological applications for the detection of sulfane sulfurs. Redox Biol. 2022 10; 56:102433. PMID: 35987086; PMCID: PMC9411671.
    Citations: 2     Fields:    Translation:Humans
  5. Flaumenhaft R, Enjyoji K, Schmaier AA. Vasculopathy in COVID-19. Blood. 2022 07 21; 140(3):222-235. PMID: 34986238; PMCID: PMC8736280.
    Citations: 4     Fields:    Translation:HumansCells
  6. Chinnaraj M, Flaumenhaft R, Pozzi N. Reduction of protein disulfide isomerase results in open conformations and stimulates dynamic exchange between structural ensembles. J Biol Chem. 2022 08; 298(8):102217. PMID: 35780832; PMCID: PMC9352907.
    Citations:    Fields:    
  7. Liao X, Zhuang X, Liang C, Li J, Flaumenhaft R, Yuan C, Huang M. Flavonoids as Protein Disulfide Isomerase Inhibitors: Key Molecular and Structural Features for the Interaction. J Agric Food Chem. 2022 Apr 13; 70(14):4475-4483. PMID: 35377153.
    Citations: 1     Fields:    Translation:AnimalsCells
  8. Mithila F, Schwake C, Fang C, Merrill-Skoloff G, Covic L, Fritz DI, Hanada T, Flaumenhaft R, Chishti AH. Calpain-1 inhibition attenuates in vivo thrombosis in a humanized model of sickle cell disease. Thromb Res. 2022 03; 211:123-126. PMID: 35149397; PMCID: PMC9207783.
    Citations:    Fields:    Translation:HumansCells
  9. Revollo L, Merrill-Skoloff G, De Ceunynck K, Dilks JR, Guo S, Bordoli MR, Peters CG, Noetzli L, Ionescu A, Rosen V, Italiano JE, Whitman M, Flaumenhaft R. The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation. Blood. 2022 01 06; 139(1):104-117. PMID: 34329392; PMCID: PMC8718620.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  10. Zhu W, Guo S, Homilius M, Nsubuga C, Wright SH, Quan D, Kc A, Eddy SS, Victorio RA, Beerens M, Flaumenhaft R, Deo RC, MacRae CA. PIEZO1 mediates a mechanothrombotic pathway in diabetes. Sci Transl Med. 2022 01 05; 14(626):eabk1707. PMID: 34985971.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  11. Italiano JE, Bender M, Merrill-Skoloff G, Ghevaert C, Nieswandt B, Flaumenhaft R. Microvesicles, but not platelets, bud off from mouse bone marrow megakaryocytes. Blood. 2021 11 18; 138(20):1998-2001. PMID: 34324659; PMCID: PMC8602935.
    Citations: 2     Fields:    Translation:AnimalsCells
  12. Gromotowicz-Poplawska A, Flaumenhaft R, Gholami SK, Merrill-Skoloff G, Chabielska E, Williams GH, Romero JR. Enhanced Thrombotic Responses Are Associated With Striatin Deficiency and Aldosterone. J Am Heart Assoc. 2021 11 16; 10(22):e022975. PMID: 34729990; PMCID: PMC8751928.
    Citations:    Fields:    Translation:Animals
  13. Liang C, Flaumenhaft R, Yuan C, Huang M. Vascular thiol isomerases: Structures, regulatory mechanisms, and inhibitor development. Drug Discov Today. 2022 02; 27(2):626-635. PMID: 34757205.
    Citations: 1     Fields:    Translation:HumansCells
  14. Schmaier AA, Pajares Hurtado GM, Manickas-Hill ZJ, Sack KD, Chen SM, Bhambhani V, Quadir J, Nath AK, Collier AY, Ngo D, Barouch DH, Shapiro NI, Gerszten RE, Yu XG, Peters KG, Flaumenhaft R, Parikh SM. Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19. JCI Insight. 2021 10 22; 6(20). PMID: 34506304; PMCID: PMC8564889.
    Citations: 10     Fields:    Translation:HumansCells
  15. Yang M, Flaumenhaft R. Oxidative Cysteine Modification of Thiol Isomerases in Thrombotic Disease: A Hypothesis. Antioxid Redox Signal. 2021 11 01; 35(13):1134-1155. PMID: 34121445; PMCID: PMC8817710.
    Citations:    Fields:    Translation:HumansAnimalsCells
  16. Sharda AV, Bogue T, Barr A, Mendez LM, Flaumenhaft R, Zwicker JI. Circulating Protein Disulfide Isomerase Is Associated with Increased Risk of Thrombosis in JAK2-Mutated Myeloproliferative Neoplasms. Clin Cancer Res. 2021 10 15; 27(20):5708-5717. PMID: 34400417; PMCID: PMC9170286.
    Citations: 1     Fields:    Translation:Humans
  17. Schmaier AA, Hurtado GP, Manickas-Hill ZJ, Sack KD, Chen SM, Bhambhani V, Quadir J, Nath AK, Collier AY, Ngo D, Barouch DH, Gerszten RE, Yu XG, Peters K, Flaumenhaft R, Parikh SM. Tie2 activation protects against prothrombotic endothelial dysfunction in COVID-19. medRxiv. 2021 May 17. PMID: 34031665.
    Citations:    
  18. Sharda AV, Barr AM, Harrison JA, Wilkie AR, Fang C, Mendez LM, Ghiran IC, Italiano JE, Flaumenhaft R. VWF maturation and release are controlled by 2 regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2. Blood. 2020 12 10; 136(24):2824-2837. PMID: 32614949; PMCID: PMC7731791.
    Citations: 5     Fields:    Translation:HumansCells
  19. Grover SP, Bendapudi PK, Yang M, Merrill-Skoloff G, Govindarajan V, Mitrophanov AY, Flaumenhaft R. Injury measurements improve interpretation of thrombus formation data in the cremaster arteriole laser-induced injury model of thrombosis. J Thromb Haemost. 2020 11; 18(11):3078-3085. PMID: 33456401.
    Citations: 4     Fields:    Translation:AnimalsCells
  20. Schulman S, El-Darzi E, Florido MH, Friesen M, Merrill-Skoloff G, Brake MA, Schuster CR, Lin L, Westrick RJ, Cowan CA, Flaumenhaft R, Ouwehand WH, Peerlinck K, Freson K, Turro E, Furie B. A coagulation defect arising from heterozygous premature termination of tissue factor. J Clin Invest. 2020 10 01; 130(10):5302-5312. PMID: 32663190; PMCID: PMC7524505.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  21. Chinnaraj M, Barrios DA, Frieden C, Heyduk T, Flaumenhaft R, Pozzi N. Bioorthogonal Chemistry Enables Single-Molecule FRET Measurements of Catalytically Active Protein Disulfide Isomerase. Chembiochem. 2021 01 05; 22(1):134-138. PMID: 32857455.
    Citations: 3     Fields:    Translation:HumansCells
  22. Yang M, Li W, Harberg C, Chen W, Yue H, Ferreira RB, Wynia-Smith SL, Carroll KS, Zielonka J, Flaumenhaft R, Silverstein RL, Smith BC. Cysteine sulfenylation by CD36 signaling promotes arterial thrombosis in dyslipidemia. Blood Adv. 2020 09 22; 4(18):4494-4507. PMID: 32946569; PMCID: PMC7509873.
    Citations: 4     Fields:    Translation:Animals
  23. Matsuura S, Thompson CR, Belghasem ME, Bekendam RH, Piasecki A, Leiva O, Ray A, Italiano J, Yang M, Merill-Skoloff G, Chitalia VC, Flaumenhaft R, Ravid K. Platelet Dysfunction and Thrombosis in JAK2V617F-Mutated Primary Myelofibrotic Mice. Arterioscler Thromb Vasc Biol. 2020 10; 40(10):e262-e272. PMID: 32814440.
    Citations: 12     Fields:    Translation:AnimalsCells
  24. Greve E, Lindeman SV, Scartelli C, Lin L, Flaumenhaft R, Dockendorff C. Route exploration and synthesis of the reported pyridone-based PDI inhibitor STK076545. Org Biomol Chem. 2020 09 14; 18(34):6665-6681. PMID: 32812971; PMCID: PMC7899705.
    Citations: 2     Fields:    
  25. Gao Y, Sarode A, Kokoroskos N, Ukidve A, Zhao Z, Guo S, Flaumenhaft R, Gupta AS, Saillant N, Mitragotri S. A polymer-based systemic hemostatic agent. Sci Adv. 2020 07; 6(31):eaba0588. PMID: 32775633; PMCID: PMC7394519.
    Citations: 10     Fields:    Translation:AnimalsCells
  26. Chaudhry SA, Serrata M, Tomczak L, Higgins S, Ryu J, Laprise D, Enjyoji K, Bekendam R, Kaushik V, Flaumenhaft R, Bendapudi PK. Cationic zinc is required for factor XII recruitment and activation by stimulated platelets and for thrombus formation in vivo. J Thromb Haemost. 2020 09; 18(9):2318-2328. PMID: 32542960.
    Citations: 3     Fields:    Translation:AnimalsCells
  27. Mitrophanov AY, Merrill-Skoloff G, Grover SP, Govindarajan V, Kolanjiyil A, Hariprasad DS, Unnikrishnan G, Flaumenhaft R, Reifman J. Injury Length and Arteriole Constriction Shape Clot Growth and Blood-Flow Acceleration in a Mouse Model of Thrombosis. Arterioscler Thromb Vasc Biol. 2020 09; 40(9):2114-2126. PMID: 32640902.
    Citations:    Fields:    Translation:AnimalsCells
  28. Sharda AV, Harrison J, Wilkie AR, Fang C, Mendez LM, Italiano JE, Flaumenhaft RC. VWF Exocytosis and Biogenesis of Weibel Palade Bodies in Endothelial Cells Are Differentially Controlled By Interactions between Bloc-2 and the Exocyst Complex. Blood. 2019 Nov 13; 134(Supplement_1):8. PMID: 31724014.
    Citations:    
  29. Battinelli EM, Thon JN, Okazaki R, Peters CG, Vijey P, Wilkie AR, Noetzli LJ, Flaumenhaft R, Italiano JE. Megakaryocytes package contents into separate a-granules that are differentially distributed in platelets. Blood Adv. 2019 10 22; 3(20):3092-3098. PMID: 31648331; PMCID: PMC6849942.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  30. Pettinato G, Lehoux S, Ramanathan R, Salem MM, He LX, Muse O, Flaumenhaft R, Thompson MT, Rouse EA, Cummings RD, Wen X, Fisher RA. Generation of fully functional hepatocyte-like organoids from human induced pluripotent stem cells mixed with Endothelial Cells. Sci Rep. 2019 06 20; 9(1):8920. PMID: 31222080; PMCID: PMC6586904.
    Citations: 43     Fields:    Translation:HumansCells
  31. Göös H, Fogarty CL, Sahu B, Plagnol V, Rajamäki K, Nurmi K, Liu X, Einarsdottir E, Jouppila A, Pettersson T, Vihinen H, Krjutskov K, Saavalainen P, Järvinen A, Muurinen M, Greco D, Scala G, Curtis J, Nordström D, Flaumenhaft R, Vaarala O, Kovanen PE, Keskitalo S, Ranki A, Kere J, Lehto M, Notarangelo LD, Nejentsev S, Eklund KK, Varjosalo M, Taipale J, Seppänen MRJ. Gain-of-function CEBPE mutation causes noncanonical autoinflammatory inflammasomopathy. J Allergy Clin Immunol. 2019 11; 144(5):1364-1376. PMID: 31201888.
    Citations: 13     Fields:    Translation:HumansCells
  32. Flaumenhaft R. Does GPIba prove the allosteric disulfide bond hypothesis? J Thromb Haemost. 2019 Jun; 17(6):849-851. PMID: 31152503.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  33. Zwicker JI, Schlechter BL, Stopa JD, Liebman HA, Aggarwal A, Puligandla M, Caughey T, Bauer KA, Kuemmerle N, Wong E, Wun T, McLaughlin M, Hidalgo M, Neuberg D, Furie B, Flaumenhaft R. Targeting protein disulfide isomerase with the flavonoid isoquercetin to improve hypercoagulability in advanced cancer. JCI Insight. 2019 02 21; 4(4). PMID: 30652973; PMCID: PMC6478409.
    Citations: 36     Fields:    Translation:HumansCTClinical Trials
  34. Eriksson O, Chiu J, Hogg PJ, Atkinson JP, Liszewski MK, Flaumenhaft R, Furie B. Thiol isomerase ERp57 targets and modulates the lectin pathway of complement activation. J Biol Chem. 2019 03 29; 294(13):4878-4888. PMID: 30670593; PMCID: PMC6442054.
    Citations: 6     Fields:    Translation:HumansCells
  35. Bekendam RH, Flaumenhaft R. Assays of Thiol Isomerase Enzymatic Activity. Methods Mol Biol. 2019; 1967:133-148. PMID: 31069768.
    Citations: 1     Fields:    Translation:Cells
  36. Bekendam RH, Iyu D, Passam F, Stopa JD, De Ceunynck K, Muse O, Bendapudi PK, Garnier CL, Gopal S, Crescence L, Chiu J, Furie B, Panicot-Dubois L, Hogg PJ, Dubois C, Flaumenhaft R. Protein disulfide isomerase regulation by nitric oxide maintains vascular quiescence and controls thrombus formation. J Thromb Haemost. 2018 11; 16(11):2322-2335. PMID: 30207066.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  37. Wang X, Xue G, Song M, Xu P, Chen D, Yuan C, Lin L, Flaumenhaft R, Li J, Huang M. Molecular basis of rutin inhibition of protein disulfide isomerase (PDI) by combined in silico and experimental methods. RSC Adv. 2018 May 17; 8(33):18480-18491. PMID: 35541126; PMCID: PMC9080521.
    Citations: 1     
  38. Higgins SJ, De Ceunynck K, Kellum JA, Chen X, Gu X, Chaudhry SA, Schulman S, Libermann TA, Lu S, Shapiro NI, Christiani DC, Flaumenhaft R, Parikh SM. Tie2 protects the vasculature against thrombus formation in systemic inflammation. J Clin Invest. 2018 04 02; 128(4):1471-1484. PMID: 29360642; PMCID: PMC5873892.
    Citations: 38     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  39. Sharda A, Flaumenhaft R. The life cycle of platelet granules. F1000Res. 2018; 7:236. PMID: 29560259.
    Citations: 45     Fields:    
  40. De Ceunynck K, Peters CG, Jain A, Higgins SJ, Aisiku O, Fitch-Tewfik JL, Chaudhry SA, Dockendorff C, Parikh SM, Ingber DE, Flaumenhaft R. PAR1 agonists stimulate APC-like endothelial cytoprotection and confer resistance to thromboinflammatory injury. Proc Natl Acad Sci U S A. 2018 01 30; 115(5):E982-E991. PMID: 29343648; PMCID: PMC5798377.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  41. Flaumenhaft R. Protease-Activated Receptor-1 Signaling: The Big Picture. Arterioscler Thromb Vasc Biol. 2017 10; 37(10):1809-1811. PMID: 28954808; PMCID: PMC5714320.
    Citations: 3     Fields:    Translation:Cells
  42. Flaumenhaft R. Advances in vascular thiol isomerase function. Curr Opin Hematol. 2017 Sep; 24(5):439-445. PMID: 28598864; PMCID: PMC5860876.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  43. Jain A, Barrile R, van der Meer AD, Mammoto A, Mammoto T, De Ceunynck K, Aisiku O, Otieno MA, Louden CS, Hamilton GA, Flaumenhaft R, Ingber DE. Primary Human Lung Alveolus-on-a-chip Model of Intravascular Thrombosis for Assessment of Therapeutics. Clin Pharmacol Ther. 2018 02; 103(2):332-340. PMID: 28516446; PMCID: PMC5693794.
    Citations: 85     Fields:    Translation:HumansCells
  44. Flaumenhaft R, De Ceunynck K. Targeting PAR1: Now What? Trends Pharmacol Sci. 2017 08; 38(8):701-716. PMID: 28558960; PMCID: PMC5580498.
    Citations: 28     Fields:    Translation:HumansAnimals
  45. Stopa JD, Baker KM, Grover SP, Flaumenhaft R, Furie B. Kinetic-based trapping by intervening sequence variants of the active sites of protein-disulfide isomerase identifies platelet protein substrates. J Biol Chem. 2017 06 02; 292(22):9063-9074. PMID: 28364042.
    Citations: 15     Fields:    Translation:HumansCells
  46. Flaumenhaft R. Stressed platelets ASK1 for a MAPK. Blood. 2017 03 02; 129(9):1066-1068. PMID: 28254824; PMCID: PMC5374735.
    Citations: 3     Fields:    Translation:HumansCells
  47. Stopa JD, Neuberg D, Puligandla M, Furie B, Flaumenhaft R, Zwicker JI. Protein disulfide isomerase inhibition blocks thrombin generation in humans by interfering with platelet factor V activation. JCI Insight. 2017 01 12; 2(1):e89373. PMID: 28097231.
    Citations: 44     Fields:    Translation:HumansAnimalsCTClinical Trials
  48. Schiemer J, Bohm A, Lin L, Merrill-Skoloff G, Flaumenhaft R, Huang JS, Le Breton GC, Chishti AH. Ga13 Switch Region 2 Relieves Talin Autoinhibition to Activate aIIbß3 Integrin. J Biol Chem. 2016 Dec 23; 291(52):26598-26612. PMID: 27803165.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  49. Flaumenhaft R. Young platelets out-of-control. Thromb Haemost. 2016 10 28; 116(5):780. PMID: 27683761.
    Citations:    Fields:    Translation:HumansCells
  50. Atefi G, Aisiku O, Shapiro N, Hauser C, Dalle Lucca J, Flaumenhaft R, Tsokos GC. Complement Activation in Trauma Patients Alters Platelet Function. Shock. 2016 09; 46(3 Suppl 1):83-8. PMID: 27355402.
    Citations: 11     Fields:    Translation:HumansCells
  51. Bekendam RH, Bendapudi PK, Lin L, Nag PP, Pu J, Kennedy DR, Feldenzer A, Chiu J, Cook KM, Furie B, Huang M, Hogg PJ, Flaumenhaft R. A substrate-driven allosteric switch that enhances PDI catalytic activity. Nat Commun. 2016 08 30; 7:12579. PMID: 27573496.
    Citations: 48     Fields:    Translation:HumansAnimalsCells
  52. Flaumenhaft R. SERCAmnavigating calcium signaling in platelets. Blood. 2016 08 25; 128(8):1034-5. PMID: 27563149; PMCID: PMC5000840.
    Citations: 1     Fields:    Translation:HumansCells
  53. Flaumenhaft R, Furie B. Vascular thiol isomerases. Blood. 2016 08 18; 128(7):893-901. PMID: 27357699; PMCID: PMC4990854.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  54. Gong L, Proulle V, Fang C, Hong Z, Lin Z, Liu M, Xue G, Yuan C, Lin L, Furie B, Flaumenhaft R, Andreasen P, Furie B, Huang M. A specific plasminogen activator inhibitor-1 antagonist derived from inactivated urokinase. J Cell Mol Med. 2016 10; 20(10):1851-60. PMID: 27197780; PMCID: PMC4876229.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  55. Bekendam RH, Flaumenhaft R. Inhibition of Protein Disulfide Isomerase in Thrombosis. Basic Clin Pharmacol Toxicol. 2016 Oct; 119 Suppl 3:42-48. PMID: 26919268.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  56. Flaumenhaft R. Probing for thiol isomerase activity in thrombi. J Thromb Haemost. 2016 05; 14(5):1067-9. PMID: 26854753; PMCID: PMC5540659.
    Citations:    Fields:    Translation:Humans
  57. Jain A, Graveline A, Waterhouse A, Vernet A, Flaumenhaft R, Ingber DE. A shear gradient-activated microfluidic device for automated monitoring of whole blood haemostasis and platelet function. Nat Commun. 2016 Jan 06; 7:10176. PMID: 26733371.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  58. Schulman S, Bendapudi P, Sharda A, Chen V, Bellido-Martin L, Jasuja R, Furie BC, Flaumenhaft R, Furie B. Extracellular Thiol Isomerases and Their Role in Thrombus Formation. Antioxid Redox Signal. 2016 Jan 01; 24(1):1-15. PMID: 26467859; PMCID: PMC4717499.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  59. Lin L, Gopal S, Sharda A, Passam F, Bowley SR, Stopa J, Xue G, Yuan C, Furie BC, Flaumenhaft R, Huang M, Furie B. Quercetin-3-rutinoside Inhibits Protein Disulfide Isomerase by Binding to Its b'x Domain. J Biol Chem. 2015 Sep 25; 290(39):23543-52. PMID: 26240139.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  60. Flaumenhaft R. A new story ARC for a-granule formation. Blood. 2015 Jul 09; 126(2):123-4. PMID: 26160182.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  61. Koseoglu S, Peters CG, Fitch-Tewfik JL, Aisiku O, Danglot L, Galli T, Flaumenhaft R. VAMP-7 links granule exocytosis to actin reorganization during platelet activation. Blood. 2015 Jul 30; 126(5):651-60. PMID: 25999457; PMCID: PMC4520880.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  62. Sakurai Y, Fitch-Tewfik JL, Qiu Y, Ahn B, Myers DR, Tran R, Fay ME, Ding L, Spearman PW, Michelson AD, Flaumenhaft R, Lam WA. Platelet geometry sensing spatially regulates a-granule secretion to enable matrix self-deposition. Blood. 2015 Jul 23; 126(4):531-8. PMID: 25964667; PMCID: PMC4513253.
    Citations: 11     Fields:    Translation:HumansCells
  63. Sharda A, Kim SH, Jasuja R, Gopal S, Flaumenhaft R, Furie BC, Furie B. Defective PDI release from platelets and endothelial cells impairs thrombus formation in Hermansky-Pudlak syndrome. Blood. 2015 Mar 05; 125(10):1633-42. PMID: 25593336; PMCID: PMC4351508.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  64. Aisiku O, Peters CG, De Ceunynck K, Ghosh CC, Dilks JR, Fustolo-Gunnink SF, Huang M, Dockendorff C, Parikh SM, Flaumenhaft R. Parmodulins inhibit thrombus formation without inducing endothelial injury caused by vorapaxar. Blood. 2015 Mar 19; 125(12):1976-85. PMID: 25587041; PMCID: PMC4366627.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  65. Flaumenhaft R. Making (anti)sense of factor XI in thrombosis. N Engl J Med. 2015 Jan 15; 372(3):277-8. PMID: 25482334.
    Citations: 2     Fields:    Translation:Humans
  66. Flaumenhaft R. Thrombus formation reimagined. Blood. 2014 Sep 11; 124(11):1697-8. PMID: 25214193; PMCID: PMC4162099.
    Citations: 6     Fields:    Translation:HumansAnimals
  67. Flaumenhaft R, Furie B, Zwicker JI. Therapeutic implications of protein disulfide isomerase inhibition in thrombotic disease. Arterioscler Thromb Vasc Biol. 2015 Jan; 35(1):16-23. PMID: 25104801.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  68. Furie B, Flaumenhaft R. Thiol isomerases in thrombus formation. Circ Res. 2014 Mar 28; 114(7):1162-73. PMID: 24677236.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  69. Flaumenhaft R. Bioengineering in platelet biology. Thromb Res. 2014 Apr; 133(4):523-4. PMID: 24433610.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  70. Battinelli EM, Markens BA, Kulenthirarajan RA, Machlus KR, Flaumenhaft R, Italiano JE. Anticoagulation inhibits tumor cell-mediated release of platelet angiogenic proteins and diminishes platelet angiogenic response. Blood. 2014 Jan 02; 123(1):101-12. PMID: 24065244; PMCID: PMC3879901.
    Citations: 41     Fields:    Translation:HumansCells
  71. Koseoglu S, Flaumenhaft R. Advances in platelet granule biology. Curr Opin Hematol. 2013 Sep; 20(5):464-71. PMID: 23839294.
    Citations: 29     Fields:    Translation:HumansCells
  72. Fitch-Tewfik JL, Flaumenhaft R. Platelet granule exocytosis: a comparison with chromaffin cells. Front Endocrinol (Lausanne). 2013; 4:77. PMID: 23805129.
    Citations: 22     Fields:    
  73. Flaumenhaft R. Protein disulfide isomerase as an antithrombotic target. Trends Cardiovasc Med. 2013 Oct; 23(7):264-8. PMID: 23541171.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  74. Koseoglu S, Dilks JR, Peters CG, Fitch-Tewfik JL, Fadel NA, Jasuja R, Italiano JE, Haynes CL, Flaumenhaft R. Dynamin-related protein-1 controls fusion pore dynamics during platelet granule exocytosis. Arterioscler Thromb Vasc Biol. 2013 Mar; 33(3):481-8. PMID: 23288151.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  75. Flaumenhaft R. a-granules: a story in the making. Blood. 2012 Dec 13; 120(25):4908-9. PMID: 23243155.
    Citations: 1     Fields:    Translation:HumansCells
  76. Flaumenhaft R. Monitoring granule traffic in megakaryocytes. Blood. 2012 Nov 08; 120(19):3869-70. PMID: 23144159.
    Citations:    Fields:    Translation:HumansCells
  77. Thon JN, Peters CG, Machlus KR, Aslam R, Rowley J, Macleod H, Devine MT, Fuchs TA, Weyrich AS, Semple JW, Flaumenhaft R, Italiano JE. T granules in human platelets function in TLR9 organization and signaling. J Cell Biol. 2012 Aug 20; 198(4):561-74. PMID: 22908309.
    Citations: 75     Fields:    Translation:HumansAnimalsCells
  78. Peters CG, Michelson AD, Flaumenhaft R. Granule exocytosis is required for platelet spreading: differential sorting of a-granules expressing VAMP-7. Blood. 2012 Jul 05; 120(1):199-206. PMID: 22589474; PMCID: PMC3390958.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  79. Jasuja R, Passam FH, Kennedy DR, Kim SH, van Hessem L, Lin L, Bowley SR, Joshi SS, Dilks JR, Furie B, Furie BC, Flaumenhaft R. Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents. J Clin Invest. 2012 Jun; 122(6):2104-13. PMID: 22565308; PMCID: PMC3366406.
    Citations: 112     Fields:    Translation:HumansAnimalsCells
  80. Ashitate Y, Kim SH, Tanaka E, Henary M, Choi HS, Frangioni JV, Flaumenhaft R. Two-wavelength near-infrared fluorescence for the quantitation of drug antiplatelet effects in large animal model systems. J Vasc Surg. 2012 Jul; 56(1):171-80. PMID: 22503225.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  81. Dockendorff C, Aisiku O, Verplank L, Dilks JR, Smith DA, Gunnink SF, Dowal L, Negri J, Palmer M, Macpherson L, Schreiber SL, Flaumenhaft R. Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor. ACS Med Chem Lett. 2012 Mar 08; 3(3):232-237. PMID: 22408714.
    Citations: 16     
  82. Flaumenhaft R. Platelets get the message. Blood. 2011 Aug 18; 118(7):1712-3. PMID: 21852441.
    Citations: 2     Fields:    
  83. Dowal L, Yang W, Freeman MR, Steen H, Flaumenhaft R. Proteomic analysis of palmitoylated platelet proteins. Blood. 2011 Sep 29; 118(13):e62-73. PMID: 21813449; PMCID: PMC3186346.
    Citations: 51     Fields:    Translation:HumansCells
  84. Nachtigall MJ, Jessel RH, Flaumenhaft R, Nachtigall R, Yoles I, Naftolin F, Nachtigall LE. The selective estrogen receptor modulator DT56a (Femarelle) does not affect platelet reactivity in normal or thrombophilic postmenopausal women. Menopause. 2011 Mar; 18(3):285-8. PMID: 21037489.
    Citations: 2     Fields:    Translation:HumansCells
  85. Dowal L, Sim DS, Dilks JR, Blair P, Beaudry S, Denker BM, Koukos G, Kuliopulos A, Flaumenhaft R. Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1. Proc Natl Acad Sci U S A. 2011 Feb 15; 108(7):2951-6. PMID: 21282664.
    Citations: 34     Fields:    Translation:AnimalsCells
  86. Liu J, Gao BB, Clermont AC, Blair P, Chilcote TJ, Sinha S, Flaumenhaft R, Feener EP. Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein. Nat Med. 2011 Feb; 17(2):206-10. PMID: 21258336.
    Citations: 55     Fields:    Translation:Animals
  87. Flaumenhaft R. Filling a void in Gray Platelets. Blood. 2010 Dec 02; 116(23):4738-40. PMID: 21127182.
    Citations: 1     Fields:    
  88. Flaumenhaft R, Mairuhu AT, Italiano JE. Platelet- and megakaryocyte-derived microparticles. Semin Thromb Hemost. 2010 Nov; 36(8):881-7. PMID: 21049389.
    Citations: 22     Fields:    Translation:HumansCells
  89. Italiano JE, Mairuhu AT, Flaumenhaft R. Clinical relevance of microparticles from platelets and megakaryocytes. Curr Opin Hematol. 2010 Nov; 17(6):578-84. PMID: 20739880.
    Citations: 102     Fields:    Translation:HumansAnimalsCells
  90. Woronowicz K, Dilks JR, Rozenvayn N, Dowal L, Blair PS, Peters CG, Woronowicz L, Flaumenhaft R. The platelet actin cytoskeleton associates with SNAREs and participates in alpha-granule secretion. Biochemistry. 2010 Jun 01; 49(21):4533-42. PMID: 20429610.
    Citations: 26     Fields:    Translation:HumansCells
  91. Dowal L, Flaumenhaft R. Targeting platelet G-protein coupled receptors (GPCRs): looking beyond conventional GPCR antagonism. Curr Vasc Pharmacol. 2010 Mar; 8(2):140-54. PMID: 19485898.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  92. Flaumenhaft R. Getting in shape with RanBP10. Blood. 2009 Dec 24; 114(27):5412-3. PMID: 20035043.
    Citations: 2     Fields:    
  93. Tanaka E, Chen FY, Flaumenhaft R, Graham GJ, Laurence RG, Frangioni JV. Real-time assessment of cardiac perfusion, coronary angiography, and acute intravascular thrombi using dual-channel near-infrared fluorescence imaging. J Thorac Cardiovasc Surg. 2009 Jul; 138(1):133-40. PMID: 19577070; PMCID: PMC2706783.
    Citations: 32     Fields:    Translation:Animals
  94. Blair P, Flaumenhaft R. Platelet alpha-granules: basic biology and clinical correlates. Blood Rev. 2009 Jul; 23(4):177-89. PMID: 19450911.
    Citations: 309     Fields:    Translation:HumansAnimalsCells
  95. Graham GJ, Ren Q, Dilks JR, Blair P, Whiteheart SW, Flaumenhaft R. Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo. Blood. 2009 Jul 30; 114(5):1083-90. PMID: 19395672; PMCID: PMC2721786.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  96. Flaumenhaft R, Nachtigall M, Lowenstein J, Nachtigall L, Nachtigall R, Nachtigall L. Association of oral but not transdermal estrogen therapy with enhanced platelet reactivity in a subset of postmenopausal women. Menopause. 2009 Mar-Apr; 16(2):407-12. PMID: 18989235.
    Citations: 2     Fields:    Translation:HumansCells
  97. Flaumenhaft R, Dilks JR, Richardson J, Alden E, Patel-Hett SR, Battinelli E, Klement GL, Sola-Visner M, Italiano JE. Megakaryocyte-derived microparticles: direct visualization and distinction from platelet-derived microparticles. Blood. 2009 Jan 29; 113(5):1112-21. PMID: 18802008; PMCID: PMC2635076.
    Citations: 109     Fields:    Translation:HumansAnimalsCells
  98. Flaumenhaft R, Dilks JR. Discovery-based strategies for studying platelet function. Mini Rev Med Chem. 2008 Apr; 8(4):350-7. PMID: 18473926.
    Citations: 2     Fields:    Translation:HumansCells
  99. Dilks JR, Flaumenhaft R. Fluoxetine (Prozac) augments platelet activation mediated through protease-activated receptors. J Thromb Haemost. 2008 Apr; 6(4):705-8. PMID: 18194419.
    Citations: 3     Fields:    Translation:HumansCells
  100. Flaumenhaft R, Rozenvayn N, Feng D, Dvorak AM. SNAP-23 and syntaxin-2 localize to the extracellular surface of the platelet plasma membrane. Blood. 2007 Sep 01; 110(5):1492-501. PMID: 17485553; PMCID: PMC1975852.
    Citations: 5     Fields:    Translation:HumansCellsCTClinical Trials
  101. Sim DS, Dilks JR, Flaumenhaft R. Platelets possess and require an active protein palmitoylation pathway for agonist-mediated activation and in vivo thrombus formation. Arterioscler Thromb Vasc Biol. 2007 Jun; 27(6):1478-85. PMID: 17303775.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  102. Flaumenhaft R, Tanaka E, Graham GJ, De Grand AM, Laurence RG, Hoshino K, Hajjar RJ, Frangioni JV. Localization and quantification of platelet-rich thrombi in large blood vessels with near-infrared fluorescence imaging. Circulation. 2007 Jan 02; 115(1):84-93. PMID: 17179017; PMCID: PMC2542837.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  103. Flaumenhaft R. Formation and fate of platelet microparticles. Blood Cells Mol Dis. 2006 Mar-Apr; 36(2):182-7. PMID: 16466949.
    Citations: 48     Fields:    Translation:HumansCells
  104. Flaumenhaft R, Lo EH. Different strokes for rodent folks. Nat Methods. 2006 Feb; 3(2):79-80. PMID: 16432514.
    Citations: 1     Fields:    Translation:Animals
  105. Flaumenhaft R, Sim DS. Protein palmitoylation in signal transduction of hematopoietic cells. Hematology. 2005 Dec; 10(6):511-9. PMID: 16321817.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  106. O'Connell DJ, Rozenvayn N, Flaumenhaft R. Phosphatidylinositol 4,5-bisphosphate regulates activation-induced platelet microparticle formation. Biochemistry. 2005 Apr 26; 44(16):6361-70. PMID: 15835925.
    Citations: 5     Fields:    Translation:HumansCells
  107. Sim D, Flaumenhaft R, Furie B, Furie B. Interactions of platelets, blood-borne tissue factor, and fibrin during arteriolar thrombus formation in vivo. Microcirculation. 2005 Apr-May; 12(3):301-11. PMID: 15814438.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  108. Flaumenhaft R, Dilks JR, Rozenvayn N, Monahan-Earley RA, Feng D, Dvorak AM. The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretion. Blood. 2005 May 15; 105(10):3879-87. PMID: 15671445.
    Citations: 41     Fields:    Translation:HumansCells
  109. Flaumenhaft R. Platelet permeabilization. Methods Mol Biol. 2004; 273:365-78. PMID: 15308812.
    Citations: 2     Fields:    Translation:HumansCells
  110. Falati S, Gross PL, Merrill-Skoloff G, Sim D, Flaumenhaft R, Celi A, Furie BC, Furie B. In vivo models of platelet function and thrombosis: study of real-time thrombus formation. Methods Mol Biol. 2004; 272:187-97. PMID: 15226545.
    Citations: 15     Fields:    Translation:AnimalsCells
  111. Sim DS, Merrill-Skoloff G, Furie BC, Furie B, Flaumenhaft R. Initial accumulation of platelets during arterial thrombus formation in vivo is inhibited by elevation of basal cAMP levels. Blood. 2004 Mar 15; 103(6):2127-34. PMID: 14645013.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  112. Flaumenhaft R, Sim DS. The platelet as a model for chemical genetics. Chem Biol. 2003 Jun; 10(6):481-6. PMID: 12837380.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  113. Flaumenhaft R. Molecular basis of platelet granule secretion. Arterioscler Thromb Vasc Biol. 2003 Jul 01; 23(7):1152-60. PMID: 12738684.
    Citations: 45     Fields:    Translation:Cells
  114. Lai KC, Flaumenhaft R. SNARE protein degradation upon platelet activation: calpain cleaves SNAP-23. J Cell Physiol. 2003 Feb; 194(2):206-14. PMID: 12494459.
    Citations: 5     Fields:    Translation:HumansCells
  115. Celi A, Merrill-Skoloff G, Gross P, Falati S, Sim DS, Flaumenhaft R, Furie BC, Furie B. Thrombus formation: direct real-time observation and digital analysis of thrombus assembly in a living mouse by confocal and widefield intravital microscopy. J Thromb Haemost. 2003 Jan; 1(1):60-8. PMID: 12871540.
    Citations: 38     Fields:    Translation:AnimalsCells
  116. Rozenvayn N, Flaumenhaft R. Protein kinase C mediates translocation of type II phosphatidylinositol 5-phosphate 4-kinase required for platelet alpha-granule secretion. J Biol Chem. 2003 Mar 07; 278(10):8126-34. PMID: 12509423.
    Citations: 10     Fields:    Translation:HumansCells
  117. Feng D, Crane K, Rozenvayn N, Dvorak AM, Flaumenhaft R. Subcellular distribution of 3 functional platelet SNARE proteins: human cellubrevin, SNAP-23, and syntaxin 2. Blood. 2002 Jun 01; 99(11):4006-14. PMID: 12010801.
    Citations: 25     Fields:    Translation:HumansCells
  118. Furie B, Furie BC, Flaumenhaft R. A journey with platelet P-selectin: the molecular basis of granule secretion, signalling and cell adhesion. Thromb Haemost. 2001 Jul; 86(1):214-21. PMID: 11487009.
    Citations: 42     Fields:    Translation:HumansCells
  119. Rozenvayn N, Flaumenhaft R. Phosphatidylinositol 4,5-bisphosphate mediates Ca2+-induced platelet alpha-granule secretion: evidence for type II phosphatidylinositol 5-phosphate 4-kinase function. J Biol Chem. 2001 Jun 22; 276(25):22410-9. PMID: 11304526.
    Citations: 7     Fields:    Translation:HumansCells
  120. Feng D, Flaumenhaft R, Bandeira-Melo C, Weller P, Dvorak A. Ultrastructural localization of vesicle-associated membrane protein(s) to specialized membrane structures in human pericytes, vascular smooth muscle cells, endothelial cells, neutrophils, and eosinophils. J Histochem Cytochem. 2001 Mar; 49(3):293-304. PMID: 11181732.
    Citations: 13     Fields:    Translation:HumansCells
  121. Yang J, Hirata T, Croce K, Merrill-Skoloff G, Tchernychev B, Williams E, Flaumenhaft R, Furie BC, Furie B. Targeted gene disruption demonstrates that P-selectin glycoprotein ligand 1 (PSGL-1) is required for P-selectin-mediated but not E-selectin-mediated neutrophil rolling and migration. J Exp Med. 1999 Dec 20; 190(12):1769-82. PMID: 10601352; PMCID: PMC2195714.
    Citations: 83     Fields:    Translation:AnimalsCells
  122. Croce K, Flaumenhaft R, Rivers M, Furie B, Furie BC, Herman IM, Potter DA. Inhibition of calpain blocks platelet secretion, aggregation, and spreading. J Biol Chem. 1999 Dec 17; 274(51):36321-7. PMID: 10593923.
    Citations: 30     Fields:    Translation:HumansCells
  123. Flaumenhaft R, Furie B, Furie BC. Alpha-granule secretion from alpha-toxin permeabilized, MgATP-exposed platelets is induced independently by H+ and Ca2+. J Cell Physiol. 1999 Apr; 179(1):1-10. PMID: 10082126.
    Citations: 5     Fields:    Translation:HumansCells
  124. Flaumenhaft R, Croce K, Chen E, Furie B, Furie BC. Proteins of the exocytotic core complex mediate platelet alpha-granule secretion. Roles of vesicle-associated membrane protein, SNAP-23, and syntaxin 4. J Biol Chem. 1999 Jan 22; 274(4):2492-501. PMID: 9891020.
    Citations: 33     Fields:    Translation:HumansCells
  125. Thorpe CM, Flaumenhaft R, Hurley B, Jacewicz M, Acheson DW, Keusch GT. Shiga toxins do not directly stimulate alpha-granule secretion or enhance aggregation of human platelets. Acta Haematol. 1999; 102(1):51-5. PMID: 10473889.
    Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
  126. Flaumenhaft R, Abe M, Sato Y, Miyazono K, Harpel J, Heldin CH, Rifkin DB. Role of the latent TGF-beta binding protein in the activation of latent TGF-beta by co-cultures of endothelial and smooth muscle cells. J Cell Biol. 1993 Feb; 120(4):995-1002. PMID: 8432736; PMCID: PMC2200078.
    Citations: 54     Fields:    Translation:AnimalsCells
  127. Flaumenhaft R, Kojima S, Abe M, Rifkin DB. Activation of latent transforming growth factor beta. Adv Pharmacol. 1993; 24:51-76. PMID: 8504067.
    Citations: 21     Fields:    Translation:HumansAnimals
  128. Flaumenhaft R, Rifkin DB. The extracellular regulation of growth factor action. Mol Biol Cell. 1992 Oct; 3(10):1057-65. PMID: 1421565; PMCID: PMC275670.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
  129. Flaumenhaft R, Abe M, Mignatti P, Rifkin DB. Basic fibroblast growth factor-induced activation of latent transforming growth factor beta in endothelial cells: regulation of plasminogen activator activity. J Cell Biol. 1992 Aug; 118(4):901-9. PMID: 1380001; PMCID: PMC2289566.
    Citations: 37     Fields:    Translation:AnimalsCells
  130. Flaumenhaft R, Rifkin DB. Cell density dependent effects of TGF-beta demonstrated by a plasminogen activator-based assay for TGF-beta. J Cell Physiol. 1992 Jul; 152(1):48-55. PMID: 1618922.
    Citations: 4     Fields:    Translation:AnimalsCells
  131. Flaumenhaft R, Rifkin DB. Extracellular matrix regulation of growth factor and protease activity. Curr Opin Cell Biol. 1991 Oct; 3(5):817-23. PMID: 1931082.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  132. Moscatelli D, Flaumenhaft R, Saksela O. Interaction of basic fibroblast growth factor with extracellular matrix and receptors. Ann N Y Acad Sci. 1991; 638:177-81. PMID: 1664684.
    Citations: 1     Fields:    Translation:AnimalsCells
  133. Rifkin DB, Moscatelli D, Flaumenhaft R, Sato Y, Saksela O, Tsuboi R. Mechanisms controlling the extracellular activity of basic fibroblast growth factor and transforming growth factor. Ann N Y Acad Sci. 1991; 614:250-8. PMID: 2024887.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  134. Rifkin DB, Moscatelli D, Bizik J, Quarto N, Blei F, Dennis P, Flaumenhaft R, Mignatti P. Growth factor control of extracellular proteolysis. Cell Differ Dev. 1990 Dec 02; 32(3):313-8. PMID: 1711916.
    Citations: 17     Fields:    Translation:AnimalsCells
  135. Flaumenhaft R, Moscatelli D, Rifkin DB. Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor. J Cell Biol. 1990 Oct; 111(4):1651-9. PMID: 2170425; PMCID: PMC2116237.
    Citations: 45     Fields:    Translation:AnimalsCells
  136. Flaumenhaft R, Moscatelli D, Saksela O, Rifkin DB. Role of extracellular matrix in the action of basic fibroblast growth factor: matrix as a source of growth factor for long-term stimulation of plasminogen activator production and DNA synthesis. J Cell Physiol. 1989 Jul; 140(1):75-81. PMID: 2738111.
    Citations: 35     Fields:    Translation:AnimalsCells
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