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David Brandon Thompson, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Nangle SN, Wolfson MY, Hartsough L, Ma NJ, Mason CE, Merighi M, Nathan V, Silver PA, Simon M, Swett J, Thompson DB, Ziesack M. The case for biotech on Mars. Nat Biotechnol. 2020 04; 38(4):401-407. PMID: 32265561.
  2. Kim YB, Zhao KT, Thompson DB, Liu DR. An anionic human protein mediates cationic liposome delivery of genome editing proteins into mammalian cells. Nat Commun. 2019 07 02; 10(1):2905. PMID: 31266953.
  3. Bessen JL, Afeyan LK, Dancík V, Koblan LW, Thompson DB, Leichner C, Clemons PA, Liu DR. Addendum: High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases. Nat Commun. 2019 07 02; 10(1):3003. PMID: 31266947.
  4. Bessen JL, Afeyan LK, Dancík V, Koblan LW, Thompson DB, Leichner C, Clemons PA, Liu DR. High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases. Nat Commun. 2019 04 26; 10(1):1937. PMID: 31028261.
  5. Thompson DB, Aboulhouda S, Hysolli E, Smith CJ, Wang S, Castanon O, Church GM. The Future of Multiplexed Eukaryotic Genome Engineering. ACS Chem Biol. 2018 02 16; 13(2):313-325. PMID: 29241002.
    Citations:    Fields:    Translation:HumansAnimals
  6. Gao X, Tao Y, Lamas V, Huang M, Yeh WH, Pan B, Hu YJ, Hu JH, Thompson DB, Shu Y, Li Y, Wang H, Yang S, Xu Q, Polley DB, Liberman MC, Kong WJ, Holt JR, Chen ZY, Liu DR. Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents. Nature. 2018 01 11; 553(7687):217-221. PMID: 29258297.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  7. Chaikind B, Bessen JL, Thompson DB, Hu JH, Liu DR. A programmable Cas9-serine recombinase fusion protein that operates on DNA sequences in mammalian cells. Nucleic Acids Res. 2016 Nov 16; 44(20):9758-9770. PMID: 27515511.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  8. Davis KM, Pattanayak V, Thompson DB, Zuris JA, Liu DR. Small molecule-triggered Cas9 protein with improved genome-editing specificity. Nat Chem Biol. 2015 May; 11(5):316-8. PMID: 25848930.
    Citations: 63     Fields:    Translation:HumansCells
  9. Zuris JA, Thompson DB, Shu Y, Guilinger JP, Bessen JL, Hu JH, Maeder ML, Joung JK, Chen ZY, Liu DR. Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo. Nat Biotechnol. 2015 Jan; 33(1):73-80. PMID: 25357182.
    Citations: 185     Fields:    
  10. Guilinger JP, Thompson DB, Liu DR. Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification. Nat Biotechnol. 2014 Jun; 32(6):577-582. PMID: 24770324.
    Citations: 199     Fields:    Translation:HumansCells
  11. Thompson DB, Villaseñor R, Dorr BM, Zerial M, Liu DR. Cellular uptake mechanisms and endosomal trafficking of supercharged proteins. Chem Biol. 2012 Jul 27; 19(7):831-43. PMID: 22840771.
    Citations: 15     Fields:    Translation:HumansCells
  12. Thompson DB, Cronican JJ, Liu DR. Engineering and identifying supercharged proteins for macromolecule delivery into mammalian cells. Methods Enzymol. 2012; 503:293-319. PMID: 22230574.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  13. Cronican JJ, Beier KT, Davis TN, Tseng JC, Li W, Thompson DB, Shih AF, May EM, Cepko CL, Kung AL, Zhou Q, Liu DR. A class of human proteins that deliver functional proteins into mammalian cells in vitro and in vivo. Chem Biol. 2011 Jul 29; 18(7):833-8. PMID: 21802004.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  14. Cronican JJ, Thompson DB, Beier KT, McNaughton BR, Cepko CL, Liu DR. Potent delivery of functional proteins into Mammalian cells in vitro and in vivo using a supercharged protein. ACS Chem Biol. 2010 Aug 20; 5(8):747-52. PMID: 20545362.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  15. McNaughton BR, Cronican JJ, Thompson DB, Liu DR. Mammalian cell penetration, siRNA transfection, and DNA transfection by supercharged proteins. Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15):6111-6. PMID: 19307578.
    Citations: 59     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.