Harvard Catalyst Profiles

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Ionita Calin Ghiran, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. UG3TR002881 (GHIRAN, IONITA CALIN) Sep 16, 2019 - Jun 30, 2021
    NIH/NCATS
    Integrative, multi-parametric characterization of the EV surface protein and nucleic acid landscape by nano-flow and sorting cytometry
    Role: Principal Investigator
  2. UG3HL147353 (GHIRAN, IONITA CALIN) Sep 15, 2018 - Jul 31, 2021
    NIH/NHLBI
    Bioengineered red blood cells as extracellular vesicle-mediated delivery platforms for gene editing machinery
    Role: Principal Investigator
  3. R01CA218500 (IVANOV, ALEXANDER R.) Mar 15, 2018 - Feb 28, 2023
    NIH/NCI
    Effect of methodological and biological variability on molecular profiling of extracellular vesicles in cancer detection
    Role: Co-Principal Investigator
  4. R21TW009915 (GHIRAN, IONITA CALIN) Sep 10, 2014 - Apr 30, 2016
    NIH/FIC
    Malaria screening in resource-poor settings using a simple, power-free, cell phone-friendly device
    Role: Principal Investigator
  5. U01HL126497 (GHIRAN, IONITA CALIN) Aug 1, 2014 - Apr 30, 2019
    NIH/NHLBI
    Impact of circadian rhythm in obtaining reference profiles of exRNAs in healthy i
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sharda AV, Barr AM, Harrison JA, Wilkie AR, Fang C, Mendez LM, Ghiran IC, Italiano JE, Flaumenhaft R. vWF maturation and release are controlled by two regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2. Blood. 2020 Jul 02. PMID: 32614949.
    Citations:    
  2. Rodosthenous RS, Hutchins E, Reiman R, Yeri AS, Srinivasan S, Whitsett TG, Ghiran I, Silverman MG, Laurent LC, Van Keuren-Jensen K, Das S. Profiling Extracellular Long RNA Transcriptome in Human Plasma and Extracellular Vesicles for Biomarker Discovery. iScience. 2020 Jun 26; 23(6):101182. PMID: 32512385.
    Citations:    
  3. Welsh JA, Van Der Pol E, Arkesteijn GJA, Bremer M, Brisson A, Coumans F, Dignat-George F, Duggan E, Ghiran I, Giebel B, Görgens A, Hendrix A, Lacroix R, Lannigan J, Libregts SFWM, Lozano-Andrés E, Morales-Kastresana A, Robert S, De Rond L, Tertel T, Tigges J, De Wever O, Yan X, Nieuwland R, Wauben MHM, Nolan JP, Jones JC. MIFlowCyt-EV: a framework for standardized reporting of extracellular vesicle flow cytometry experiments. J Extracell Vesicles. 2020; 9(1):1713526. PMID: 32128070.
    Citations:    
  4. Lee J, Vernet A, Redfield K, Lu S, Ghiran IC, Way JC, Silver PA. Rational Design of a Bifunctional AND-Gate Ligand To Modulate Cell-Cell Interactions. ACS Synth Biol. 2020 02 21; 9(2):191-197. PMID: 31834794.
    Citations:    
  5. Oliveira GP, Zigon E, Rogers G, Davodian D, Lu S, Jovanovic-Talisman T, Jones J, Tigges J, Tyagi S, Ghiran IC. Detection of Extracellular Vesicle RNA Using Molecular Beacons. iScience. 2020 Jan 24; 23(1):100782. PMID: 31958756.
    Citations:    
  6. Jones PS, Yekula A, Lansbury E, Small JL, Ayinon C, Mordecai S, Hochberg FH, Tigges J, Delcuze B, Charest A, Ghiran I, Balaj L, Carter BS. Characterization of plasma-derived protoporphyrin-IX-positive extracellular vesicles following 5-ALA use in patients with malignant glioma. EBioMedicine. 2019 Oct; 48:23-35. PMID: 31628025.
    Citations:    
  7. Bei Y, Xu T, Lv D, Yu P, Xu J, Che L, Das A, Tigges J, Toxavidis V, Ghiran I, Shah R, Li Y, Zhang Y, Das S, Xiao J. Correction to: Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury. Basic Res Cardiol. 2019 Oct 08; 114(6):44. PMID: 31595368.
    Citations:    
  8. Morales-Kastresana A, Musich TA, Welsh JA, Telford W, Demberg T, Wood JCS, Bigos M, Ross CD, Kachynski A, Dean A, Felton EJ, Van Dyke J, Tigges J, Toxavidis V, Parks DR, Overton WR, Kesarwala AH, Freeman GJ, Rosner A, Perfetto SP, Pasquet L, Terabe M, McKinnon K, Kapoor V, Trepel JB, Puri A, Kobayashi H, Yung B, Chen X, Guion P, Choyke P, Knox SJ, Ghiran I, Robert-Guroff M, Berzofsky JA, Jones JC. High-fidelity detection and sorting of nanoscale vesicles in viral disease and cancer. J Extracell Vesicles. 2019; 8(1):1597603. PMID: 31258878.
    Citations:    
  9. Andersen MS, Lu S, Lopez GJ, Lassen AT, Shapiro NI, Ghiran IC. A Novel Implementation of Magnetic Levitation to Quantify Leukocyte Size, Morphology, and Magnetic Properties to Identify Patients With Sepsis. Shock. 2019 02; 51(2):147-152. PMID: 29561389.
    Citations:    Fields:    
  10. Giraldez MD, Spengler RM, Etheridge A, Godoy PM, Barczak AJ, Srinivasan S, Hoff PL, Tanriverdi K, Courtright A, Lu S, Khoory J, Rubio R, Baxter D, Driedonks TAP, Buermans HPJ, Hoen ENMN, Jiang H, Wang K, Ghiran I, Wang YE, Keuren-Jensen KV, Freedman JE, Woodruff PG, Laurent LC, Erle DJ, Galas DJ, Tewari M. Erratum: Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling. Nat Biotechnol. 2018 09 06; 36(9):899. PMID: 30188530.
    Citations:    Fields:    
  11. Giraldez MD, Spengler RM, Etheridge A, Godoy PM, Barczak AJ, Srinivasan S, De Hoff PL, Tanriverdi K, Courtright A, Lu S, Khoory J, Rubio R, Baxter D, Driedonks TAP, Buermans HPJ, Nolte-'t Hoen ENM, Jiang H, Wang K, Ghiran I, Wang YE, Van Keuren-Jensen K, Freedman JE, Woodruff PG, Laurent LC, Erle DJ, Galas DJ, Tewari M. Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling. Nat Biotechnol. 2018 09; 36(8):746-757. PMID: 30010675.
    Citations: 2     Fields:    
  12. Smith AS, Nowak RB, Zhou S, Giannetto M, Gokhin DS, Papoin J, Ghiran IC, Blanc L, Wan J, Fowler VM. Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability. Proc Natl Acad Sci U S A. 2018 05 08; 115(19):E4377-E4385. PMID: 29610350.
    Citations: 5     Fields:    Translation:HumansCells
  13. Rodriguez Cetina Biefer H, Heinbokel T, Uehara H, Camacho V, Minami K, Nian Y, Koduru S, El Fatimy R, Ghiran I, Trachtenberg AJ, de la Fuente MA, Azuma H, Akbari O, Tullius SG, Vasudevan A, Elkhal A. Mast cells regulate CD4+ T-cell differentiation in the absence of antigen presentation. J Allergy Clin Immunol. 2018 12; 142(6):1894-1908.e7. PMID: 29470999.
    Citations: 1     Fields:    
  14. Babatunde KA, Mbagwu S, Hernández-Castañeda MA, Adapa SR, Walch M, Filgueira L, Falquet L, Jiang RHY, Ghiran I, Mantel PY. Malaria infected red blood cells release small regulatory RNAs through extracellular vesicles. Sci Rep. 2018 01 17; 8(1):884. PMID: 29343745.
    Citations:    Fields:    Translation:HumansAnimalsCells
  15. Andersen MS, Howard E, Lu S, Richard M, Gregory M, Ogembo G, Mazor O, Gorelik P, Shapiro NI, Sharda AV, Ghiran I. Detection of membrane-bound and soluble antigens by magnetic levitation. Lab Chip. 2017 10 11; 17(20):3462-3473. PMID: 28905952.
    Citations: 1     Fields:    Translation:HumansCells
  16. Shah R, Yeri A, Das A, Courtright-Lim A, Ziegler O, Gervino E, Ocel J, Quintero-Pinzon P, Wooster L, Bailey CS, Tanriverdi K, Beaulieu LM, Freedman JE, Ghiran I, Lewis GD, Van Keuren-Jensen K, Das S. Small RNA-seq during acute maximal exercise reveal RNAs involved in vascular inflammation and cardiometabolic health: brief report. Am J Physiol Heart Circ Physiol. 2017 Dec 01; 313(6):H1162-H1167. PMID: 28916639.
    Citations: 1     Fields:    Translation:HumansAnimals
  17. Bei Y, Xu T, Lv D, Yu P, Xu J, Che L, Das A, Tigges J, Toxavidis V, Ghiran I, Shah R, Li Y, Zhang Y, Das S, Xiao J. Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury. Basic Res Cardiol. 2017 07; 112(4):38. PMID: 28534118.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  18. Simonson B, Subramanya V, Chan MC, Zhang A, Franchino H, Ottaviano F, Mishra MK, Knight AC, Hunt D, Ghiran I, Khurana TS, Kontaridis MI, Rosenzweig A, Das S. DDiT4L promotes autophagy and inhibits pathological cardiac hypertrophy in response to stress. Sci Signal. 2017 02 28; 10(468). PMID: 28246202.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  19. Kuo WP, Tigges JC, Toxavidis V, Ghiran I. Red Blood Cells: A Source of Extracellular Vesicles. Methods Mol Biol. 2017; 1660:15-22. PMID: 28828644.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  20. Akuthota P, Carmo LA, Bonjour K, Murphy RO, Silva TP, Gamalier JP, Capron KL, Tigges J, Toxavidis V, Camacho V, Ghiran I, Ueki S, Weller PF, Melo RC. Extracellular Microvesicle Production by Human Eosinophils Activated by "Inflammatory" Stimuli. Front Cell Dev Biol. 2016; 4:117. PMID: 27833910.
    Citations: 4     
  21. Mantel PY, Hjelmqvist D, Walch M, Kharoubi-Hess S, Nilsson S, Ravel D, Ribeiro M, Grüring C, Ma S, Padmanabhan P, Trachtenberg A, Ankarklev J, Brancucci NM, Huttenhower C, Duraisingh MT, Ghiran I, Kuo WP, Filgueira L, Martinelli R, Marti M. Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria. Nat Commun. 2016 10 10; 7:12727. PMID: 27721445.
    Citations: 23     Fields:    Translation:HumansCells
  22. Felton EJ, Velasquez A, Lu S, Murphy RO, ElKhal A, Mazor O, Gorelik P, Sharda A, Ghiran IC. Detection and quantification of subtle changes in red blood cell density using a cell phone. Lab Chip. 2016 08 16; 16(17):3286-95. PMID: 27431921.
    Citations: 2     Fields:    Translation:HumansCells
  23. Elkhal A, Rodriguez Cetina Biefer H, Heinbokel T, Uehara H, Quante M, Seyda M, Schuitenmaker JM, Krenzien F, Camacho V, de la Fuente MA, Ghiran I, Tullius SG. NAD(+) regulates Treg cell fate and promotes allograft survival via a systemic IL-10 production that is CD4(+) CD25(+) Foxp3(+) T cells independent. Sci Rep. 2016 Mar 01; 6:22325. PMID: 26928119.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  24. Khoory J, Estanislau J, Elkhal A, Lazaar A, Melhorn MI, Brodsky A, Illigens B, Hamachi I, Kurishita Y, Ivanov AR, Shevkoplyas S, Shapiro NI, Ghiran IC. Ligation of Glycophorin A Generates Reactive Oxygen Species Leading to Decreased Red Blood Cell Function. PLoS One. 2016; 11(1):e0141206. PMID: 26784696.
    Citations: 6     Fields:    Translation:HumansCells
  25. Danielson KM, Estanislau J, Tigges J, Toxavidis V, Camacho V, Felton EJ, Khoory J, Kreimer S, Ivanov AR, Mantel PY, Jones J, Akuthota P, Das S, Ghiran I. Diurnal Variations of Circulating Extracellular Vesicles Measured by Nano Flow Cytometry. PLoS One. 2016; 11(1):e0144678. PMID: 26745887.
    Citations: 6     Fields:    Translation:HumansCells
  26. Knowlton SM, Sencan I, Aytar Y, Khoory J, Heeney MM, Ghiran IC, Tasoglu S. Sickle cell detection using a smartphone. Sci Rep. 2015 Oct 22; 5:15022. PMID: 26492382.
    Citations: 11     Fields:    Translation:Humans
  27. Quesenberry PJ, Aliotta J, Camussi G, Abdel-Mageed AB, Wen S, Goldberg L, Zhang HG, Tetta C, Franklin J, Coffey RJ, Danielson K, Subramanya V, Ghiran I, Das S, Chen CC, Pusic KM, Pusic AD, Chatterjee D, Kraig RP, Balaj L, Dooner M. Potential functional applications of extracellular vesicles: a report by the NIH Common Fund Extracellular RNA Communication Consortium. J Extracell Vesicles. 2015; 4:27575. PMID: 26320942.
    Citations: 7     
  28. Knowlton S, Yu CH, Jain N, Ghiran IC, Tasoglu S. Smart-Phone Based Magnetic Levitation for Measuring Densities. PLoS One. 2015; 10(8):e0134400. PMID: 26308615.
    Citations: 6     Fields:    
  29. Tasoglu S, Khoory JA, Tekin HC, Thomas C, Karnoub AE, Ghiran IC, Demirci U. Cytometry: Levitational Image Cytometry with Temporal Resolution (Adv. Mater. 26/2015). Adv Mater. 2015 Jul; 27(26):3900. PMID: 26149363.
    Citations:    
  30. Durmus NG, Tekin HC, Guven S, Sridhar K, Arslan Yildiz A, Calibasi G, Ghiran I, Davis RW, Steinmetz LM, Demirci U. Magnetic levitation of single cells. Proc Natl Acad Sci U S A. 2015 Jul 14; 112(28):E3661-8. PMID: 26124131.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  31. Tasoglu S, Khoory JA, Tekin HC, Thomas C, Karnoub AE, Ghiran IC, Demirci U. Levitational Image Cytometry with Temporal Resolution. Adv Mater. 2015 Jul 08; 27(26):3901-8. PMID: 26058598.
    Citations: 9     Fields:    Translation:HumansCells
  32. Kreimer S, Belov AM, Ghiran I, Murthy SK, Frank DA, Ivanov AR. Mass-spectrometry-based molecular characterization of extracellular vesicles: lipidomics and proteomics. J Proteome Res. 2015 Jun 05; 14(6):2367-84. PMID: 25927954.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  33. Gokhin DS, Nowak RB, Khoory JA, Piedra Ade L, Ghiran IC, Fowler VM. Dynamic actin filaments control the mechanical behavior of the human red blood cell membrane. Mol Biol Cell. 2015 May 01; 26(9):1699-710. PMID: 25717184.
    Citations: 9     Fields:    Translation:HumansCells
  34. Tullius SG, Biefer HR, Li S, Trachtenberg AJ, Edtinger K, Quante M, Krenzien F, Uehara H, Yang X, Kissick HT, Kuo WP, Ghiran I, de la Fuente MA, Arredouani MS, Camacho V, Tigges JC, Toxavidis V, El Fatimy R, Smith BD, Vasudevan A, ElKhal A. NAD+ protects against EAE by regulating CD4+ T-cell differentiation. Nat Commun. 2014 Oct 07; 5:5101. PMID: 25290058.
    Citations: 13     Fields:    Translation:AnimalsCells
  35. El Assal R, Guven S, Gurkan UA, Gozen I, Shafiee H, Dalbeyler S, Abdalla N, Thomas G, Fuld W, Illigens BM, Estanislau J, Khoory J, Kaufman R, Zylberberg C, Lindeman N, Wen Q, Ghiran I, Demirci U. Bio-inspired cryo-ink preserves red blood cell phenotype and function during nanoliter vitrification. Adv Mater. 2014 Sep 03; 26(33):5815-22. PMID: 25047246.
    Citations: 5     Fields:    Translation:HumansCells
  36. Muroya T, Kannan L, Ghiran IC, Shevkoplyas SS, Paz Z, Tsokos M, Dalle Lucca JJ, Shapiro NI, Tsokos GC. C4d deposits on the surface of RBCs in trauma patients and interferes with their function. Crit Care Med. 2014 May; 42(5):e364-72. PMID: 24448198.
    Citations: 4     Fields:    Translation:HumansCells
  37. Melhorn MI, Brodsky AS, Estanislau J, Khoory JA, Illigens B, Hamachi I, Kurishita Y, Fraser AD, Nicholson-Weller A, Dolmatova E, Duffy HS, Ghiran IC. CR1-mediated ATP release by human red blood cells promotes CR1 clustering and modulates the immune transfer process. J Biol Chem. 2013 Oct 25; 288(43):31139-53. PMID: 24022490.
    Citations: 13     Fields:    Translation:HumansCellsCTClinical Trials
  38. Mantel PY, Hoang AN, Goldowitz I, Potashnikova D, Hamza B, Vorobjev I, Ghiran I, Toner M, Irimia D, Ivanov AR, Barteneva N, Marti M. Malaria-infected erythrocyte-derived microvesicles mediate cellular communication within the parasite population and with the host immune system. Cell Host Microbe. 2013 May 15; 13(5):521-534. PMID: 23684304.
    Citations: 81     Fields:    Translation:HumansAnimalsCells
  39. Ogembo JG, Kannan L, Ghiran I, Nicholson-Weller A, Finberg RW, Tsokos GC, Fingeroth JD. Human complement receptor type 1/CD35 is an Epstein-Barr Virus receptor. Cell Rep. 2013 Feb 21; 3(2):371-85. PMID: 23416052.
    Citations: 26     Fields:    Translation:HumansCells
  40. Ueki S, Melo RC, Ghiran I, Spencer LA, Dvorak AM, Weller PF. Eosinophil extracellular DNA trap cell death mediates lytic release of free secretion-competent eosinophil granules in humans. Blood. 2013 Mar 14; 121(11):2074-83. PMID: 23303825.
    Citations: 29     Fields:    Translation:HumansCells
  41. Borschukova O, Paz Z, Ghiran IC, Liu CC, Kao AH, Manzi S, Ahearn JM, Tsokos GC. Complement fragment C3d is colocalized within the lipid rafts of T cells and promotes cytokine production. Lupus. 2012 Oct; 21(12):1294-304. PMID: 22851413.
    Citations: 3     Fields:    Translation:HumansCells
  42. Ghiran IC, Zeidel ML, Shevkoplyas SS, Burns JM, Tsokos GC, Kyttaris VC. Systemic lupus erythematosus serum deposits C4d on red blood cells, decreases red blood cell membrane deformability, and promotes nitric oxide production. Arthritis Rheum. 2011 Feb; 63(2):503-12. PMID: 21280005.
    Citations: 12     Fields:    Translation:HumansCells
  43. Ghiran IC. Introduction to fluorescence microscopy. Methods Mol Biol. 2011; 689:93-136. PMID: 21153789.
    Citations:    Fields:    Translation:Cells
  44. Ghiran IC, Zeidel ML, Shevkoplyas SS, Burns JM, Tsokos GC, Kyttaris VC. SLE serum deposits C4d on red blood cells, decreases red blood cell membrane deformability, and promotes nitric oxide production. Arthritis Rheum. 2010 Nov 15. PMID: 21080356.
    Citations:    
  45. Glodek AM, Mirchev R, Golan DE, Khoory JA, Burns JM, Shevkoplyas SS, Nicholson-Weller A, Ghiran IC. Ligation of complement receptor 1 increases erythrocyte membrane deformability. Blood. 2010 Dec 23; 116(26):6063-71. PMID: 20861458.
    Citations: 16     Fields:    Translation:HumansCells
  46. Ghiran I, Kuo WP. Examining the role of microvesicles to develop prognostic and diagnostic assays. J Appl Oral Sci. 2010 Sep-Oct; 18(5):i. PMID: 21085796.
    Citations: 2     Fields:    Translation:HumansCells
  47. Li J, Wang JP, Ghiran I, Cerny A, Szalai AJ, Briles DE, Finberg RW. Complement receptor 1 expression on mouse erythrocytes mediates clearance of Streptococcus pneumoniae by immune adherence. Infect Immun. 2010 Jul; 78(7):3129-35. PMID: 20439480.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  48. Celli JP, Turner BS, Afdhal NH, Keates S, Ghiran I, Kelly CP, Ewoldt RH, McKinley GH, So P, Erramilli S, Bansil R. Helicobacter pylori moves through mucus by reducing mucin viscoelasticity. Proc Natl Acad Sci U S A. 2009 Aug 25; 106(34):14321-6. PMID: 19706518.
    Citations: 71     Fields:    Translation:AnimalsCells
  49. Lim KH, Salahuddin S, Qiu L, Fang H, Vitkin E, Ghiran IC, Modell MD, Takoudes T, Itzkan I, Hanlon EB, Sachs BP, Perelman LT. Light-scattering spectroscopy differentiates fetal from adult nucleated red blood cells: may lead to noninvasive prenatal diagnosis. Opt Lett. 2009 May 01; 34(9):1483-5. PMID: 19412313.
    Citations: 1     Fields:    Translation:HumansCells
  50. Karnchanaphanurach P, Mirchev R, Ghiran I, Asara JM, Papahadjopoulos-Sternberg B, Nicholson-Weller A, Golan DE. C3b deposition on human erythrocytes induces the formation of a membrane skeleton-linked protein complex. J Clin Invest. 2009 Apr; 119(4):788-801. PMID: 19258706.
    Citations: 19     Fields:    Translation:HumansCells
  51. Neves JS, Perez SA, Spencer LA, Melo RC, Reynolds L, Ghiran I, Mahmudi-Azer S, Odemuyiwa SO, Dvorak AM, Moqbel R, Weller PF. Eosinophil granules function extracellularly as receptor-mediated secretory organelles. Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47):18478-83. PMID: 19017810.
    Citations: 39     Fields:    Translation:HumansCells
  52. Ghiran I, Glodek AM, Weaver G, Klickstein LB, Nicholson-Weller A. Ligation of erythrocyte CR1 induces its clustering in complex with scaffolding protein FAP-1. Blood. 2008 Oct 15; 112(8):3465-73. PMID: 18684861.
    Citations: 14     Fields:    Translation:HumansCells
  53. Costa M, Ghiran I, Peng CK, Nicholson-Weller A, Goldberger AL. Complex dynamics of human red blood cell flickering: alterations with in vivo aging. Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Aug; 78(2 Pt 1):020901. PMID: 18850779.
    Citations: 18     Fields:    Translation:HumansCells
  54. Wang HB, Ghiran I, Matthaei K, Weller PF. Airway eosinophils: allergic inflammation recruited professional antigen-presenting cells. J Immunol. 2007 Dec 01; 179(11):7585-92. PMID: 18025204.
    Citations: 63     Fields:    Translation:AnimalsCells
  55. Itzkan I, Qiu L, Fang H, Zaman MM, Vitkin E, Ghiran IC, Salahuddin S, Modell M, Andersson C, Kimerer LM, Cipolloni PB, Lim KH, Freedman SD, Bigio I, Sachs BP, Hanlon EB, Perelman LT. Confocal light absorption and scattering spectroscopic microscopy monitors organelles in live cells with no exogenous labels. Proc Natl Acad Sci U S A. 2007 Oct 30; 104(44):17255-60. PMID: 17956980.
    Citations: 35     Fields:    Translation:HumansCells
  56. Chen CH, Ghiran I, Beurskens FJ, Weaver G, Vincent JA, Nicholson-Weller A, Klickstein LB. Antibody CR1-2B11 recognizes a non-polymorphic epitope of human CR1 (CD35). Clin Exp Immunol. 2007 Jun; 148(3):546-54. PMID: 17493021.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  57. Huang IC, Bosch BJ, Li F, Li W, Lee KH, Ghiran S, Vasilieva N, Dermody TS, Harrison SC, Dormitzer PR, Farzan M, Rottier PJ, Choe H. SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells. J Biol Chem. 2006 Feb 10; 281(6):3198-203. PMID: 16339146.
    Citations: 79     Fields:    Translation:HumansAnimalsCells
  58. Melo RC, Spencer LA, Perez SA, Ghiran I, Dvorak AM, Weller PF. Human eosinophils secrete preformed, granule-stored interleukin-4 through distinct vesicular compartments. Traffic. 2005 Nov; 6(11):1047-57. PMID: 16190985.
    Citations: 38     Fields:    Translation:HumansCells
  59. Honczarenko M, Le Y, Swierkowski M, Ghiran I, Glodek AM, Silberstein LE. Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors. Stem Cells. 2006 Apr; 24(4):1030-41. PMID: 16253981.
    Citations: 169     Fields:    Translation:HumansCells
  60. Pilsczek FH, Nicholson-Weller A, Ghiran I. Phagocytosis of Salmonella montevideo by human neutrophils: immune adherence increases phagocytosis, whereas the bacterial surface determines the route of intracellular processing. J Infect Dis. 2005 Jul 15; 192(2):200-9. PMID: 15962214.
    Citations: 3     Fields:    Translation:HumansCells
  61. Repik A, Pincus SE, Ghiran I, Nicholson-Weller A, Asher DR, Cerny AM, Casey LS, Jones SM, Jones SN, Mohamed N, Klickstein LB, Spitalny G, Finberg RW. A transgenic mouse model for studying the clearance of blood-borne pathogens via human complement receptor 1 (CR1). Clin Exp Immunol. 2005 May; 140(2):230-40. PMID: 15807846.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  62. Otabor I, Tyagi S, Beurskens FJ, Ghiran I, Schwab P, Nicholson-Weller A, Klickstein LB. A role for lipid rafts in C1q-triggered O2- generation by human neutrophils. Mol Immunol. 2004 Jun; 41(2-3):185-90. PMID: 15159064.
    Citations: 3     Fields:    Translation:HumansCells
  63. Bandeira-Melo C, Perez SA, Melo RC, Ghiran I, Weller PF. EliCell assay for the detection of released cytokines from eosinophils. J Immunol Methods. 2003 May 01; 276(1-2):227-37. PMID: 12738376.
    Citations: 14     Fields:    Translation:Cells
  64. Ghiran I, Klickstein LB, Nicholson-Weller A. Calreticulin is at the surface of circulating neutrophils and uses CD59 as an adaptor molecule. J Biol Chem. 2003 Jun 06; 278(23):21024-31. PMID: 12646570.
    Citations: 21     Fields:    Translation:HumansCells
  65. Ghiran I, Tyagi SR, Klickstein LB, Nicholson-Weller A. Expression and function of C1q receptors and C1q binding proteins at the cell surface. Immunobiology. 2002 Sep; 205(4-5):407-20. PMID: 12396003.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  66. Ghiran I, Barbashov SF, Klickstein LB, Tas SW, Jensenius JC, Nicholson-Weller A. Complement receptor 1/CD35 is a receptor for mannan-binding lectin. J Exp Med. 2000 Dec 18; 192(12):1797-808. PMID: 11120776.
    Citations: 52     Fields:    Translation:HumansCells
  67. Bandeira-Melo C, Gillard G, Ghiran I, Weller PF. EliCell: a gel-phase dual antibody capture and detection assay to measure cytokine release from eosinophils. J Immunol Methods. 2000 Oct 20; 244(1-2):105-15. PMID: 11033023.
    Citations: 14     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.