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Ildiko Van Rhijn, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Suliman S, Kjer-Nielsen L, Iwany SK, Lopez Tamara K, Loh L, Grzelak L, Kedzierska K, Ocampo TA, Corbett AJ, McCluskey J, Rossjohn J, León SR, Calderon R, Lecca-Garcia L, Murray MB, Moody DB, Van Rhijn I. Dual TCR-a Expression on Mucosal-Associated Invariant T Cells as a Potential Confounder of TCR Interpretation. J Immunol. 2022 Mar 15; 208(6):1389-1395. PMID: 35246495.
    Citations:    Fields:    
  2. Reijneveld JF, Marino L, Cao TP, Cheng TY, Dam D, Shahine A, Witte MD, Filippov DV, Suliman S, van der Marel GA, Moody DB, Minnaard AJ, Rossjohn J, Codée JDC, Van Rhijn I. Rational design of a hydrolysis-resistant mycobacterial phosphoglycolipid antigen presented by CD1c to T cells. J Biol Chem. 2021 10; 297(4):101197. PMID: 34536421.
    Citations:    Fields:    Translation:HumansCells
  3. Almeida CF, Smith DGM, Cheng TY, Harpur CM, Batleska E, Nguyen-Robertson CV, Nguyen T, Thelemann T, Reddiex SJJ, Li S, Eckle SBG, Van Rhijn I, Rossjohn J, Uldrich AP, Moody DB, Williams SJ, Pellicci DG, Godfrey DI. Benzofuran sulfonates and small self-lipid antigens activate type II NKT cells via CD1d. Proc Natl Acad Sci U S A. 2021 08 24; 118(34). PMID: 34417291.
    Citations:    Fields:    Translation:HumansCells
  4. Nathan A, Beynor JI, Baglaenko Y, Suliman S, Ishigaki K, Asgari S, Huang CC, Luo Y, Zhang Z, Lopez K, Lindestam Arlehamn CS, Ernst JD, Jimenez J, Calderón RI, Lecca L, Van Rhijn I, Moody DB, Murray MB, Raychaudhuri S. Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease. Nat Immunol. 2021 06; 22(6):781-793. PMID: 34031617.
    Citations: 5     Fields:    Translation:HumansCells
  5. Cotton RN, Wegrecki M, Cheng TY, Chen YL, Veerapen N, Le Nours J, Orgill DP, Pomahac B, Talbot SG, Willis R, Altman JD, de Jong A, Van Rhijn I, Clark RA, Besra GS, Ogg G, Rossjohn J, Moody DB. CD1a selectively captures endogenous cellular lipids that broadly block T cell response. J Exp Med. 2021 07 05; 218(7). PMID: 33961028.
    Citations: 5     Fields:    Translation:HumansCells
  6. Van Rhijn I, Le Nours J. CD1 and MR1 recognition by human ?d T cells. Mol Immunol. 2021 05; 133:95-100. PMID: 33636434.
    Citations:    Fields:    Translation:HumansCells
  7. Reijneveld JF, Holzheimer M, Young DC, Lopez K, Suliman S, Jimenez J, Calderon R, Lecca L, Murray MB, Ishikawa E, Yamasaki S, Minnaard AJ, Moody DB, Van Rhijn I. Synthetic mycobacterial diacyl trehaloses reveal differential recognition by human T cell receptors and the C-type lectin Mincle. Sci Rep. 2021 01 21; 11(1):2010. PMID: 33479373.
    Citations: 1     Fields:    Translation:HumansCells
  8. Cotton RN, Cheng TY, Wegrecki M, Le Nours J, Orgill DP, Pomahac B, Talbot SG, Willis RA, Altman JD, de Jong A, Ogg G, Van Rhijn I, Rossjohn J, Clark RA, Moody DB. Human skin is colonized by T cells that recognize CD1a independently of lipid. J Clin Invest. 2021 01 04; 131(1). PMID: 33393500.
    Citations: 9     Fields:    Translation:HumansCells
  9. Reijneveld JF, Ocampo TA, Shahine A, Gully BS, Vantourout P, Hayday AC, Rossjohn J, Moody DB, Van Rhijn I. Human ?d T cells recognize CD1b by two distinct mechanisms. Proc Natl Acad Sci U S A. 2020 09 15; 117(37):22944-22952. PMID: 32868441.
    Citations: 7     Fields:    Translation:HumansCells
  10. Suliman S, Gela A, Mendelsohn SC, Iwany SK, Tamara KL, Mabwe S, Bilek N, Darboe F, Fisher M, Corbett AJ, Kjer-Nielsen L, Eckle SBG, Huang CC, Zhang Z, Lewinsohn DM, McCluskey J, Rossjohn J, Hatherill M, León SR, Calderon RI, Lecca L, Murray M, Scriba TJ, Van Rhijn I, Moody DB. Peripheral Blood Mucosal-Associated Invariant T Cells in Tuberculosis Patients and Healthy Mycobacterium tuberculosis-Exposed Controls. J Infect Dis. 2020 08 17; 222(6):995-1007. PMID: 32267943.
    Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
  11. Penn-Nicholson A, Mbandi SK, Thompson E, Mendelsohn SC, Suliman S, Chegou NN, Malherbe ST, Darboe F, Erasmus M, Hanekom WA, Bilek N, Fisher M, Kaufmann SHE, Winter J, Murphy M, Wood R, Morrow C, Van Rhijn I, Moody B, Murray M, Andrade BB, Sterling TR, Sutherland J, Naidoo K, Padayatchi N, Walzl G, Hatherill M, Zak D, Scriba TJ. RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response. Sci Rep. 2020 05 25; 10(1):8629. PMID: 32451443.
    Citations: 27     Fields:    Translation:HumansCells
  12. Holzheimer M, Reijneveld JF, Ramnarine AK, Misiakos G, Young DC, Ishikawa E, Cheng TY, Yamasaki S, Moody DB, Van Rhijn I, Minnaard AJ. Asymmetric Total Synthesis of Mycobacterial Diacyl Trehaloses Demonstrates a Role for Lipid Structure in Immunogenicity. ACS Chem Biol. 2020 07 17; 15(7):1835-1841. PMID: 32293864.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  13. Tahiri N, Fodran P, Jayaraman D, Buter J, Witte MD, Ocampo TA, Moody DB, Van Rhijn I, Minnaard AJ. Total Synthesis of a Mycolic Acid from Mycobacterium tuberculosis. Angew Chem Int Ed Engl. 2020 05 04; 59(19):7555-7560. PMID: 32067294.
    Citations: 4     Fields:    Translation:Cells
  14. Lopez K, Iwany SK, Suliman S, Reijneveld JF, Ocampo TA, Jimenez J, Calderon R, Lecca L, Murray MB, Moody DB, Van Rhijn I. CD1b Tetramers Broadly Detect T Cells That Correlate With Mycobacterial Exposure but Not Tuberculosis Disease State. Front Immunol. 2020; 11:199. PMID: 32117314.
    Citations: 9     Fields:    Translation:HumansCells
  15. Nicolai S, Wegrecki M, Cheng TY, Bourgeois EA, Cotton RN, Mayfield JA, Monnot GC, Le Nours J, Van Rhijn I, Rossjohn J, Moody DB, de Jong A. Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products. Sci Immunol. 2020 01 03; 5(43). PMID: 31901073.
    Citations: 9     Fields:    Translation:HumansCells
  16. Reinink P, Shahine A, Gras S, Cheng TY, Farquhar R, Lopez K, Suliman SA, Reijneveld JF, Le Nours J, Tan LL, León SR, Jimenez J, Calderon R, Lecca L, Murray MB, Rossjohn J, Moody DB, Van Rhijn I. A TCR ß-Chain Motif Biases toward Recognition of Human CD1 Proteins. J Immunol. 2019 12 15; 203(12):3395-3406. PMID: 31694911.
    Citations: 6     Fields:    Translation:HumansCells
  17. Mishra VK, Buter J, Blevins MS, Witte MD, Van Rhijn I, Moody DB, Brodbelt JS, Minnaard AJ. Total Synthesis of an Immunogenic Trehalose Phospholipid from Salmonella Typhi and Elucidation of Its sn-Regiochemistry by Mass Spectrometry. Org Lett. 2019 07 05; 21(13):5126-5131. PMID: 31247773.
    Citations: 2     Fields:    Translation:Cells
  18. Reinink P, Souter MNT, Cheng TY, van Gorkom T, Lenz S, Kubler-Kielb J, Strle K, Kremer K, Thijsen SFT, Steere AC, Godfrey DI, Pellicci DG, Moody DB, Van Rhijn I. CD1b presents self and Borrelia burgdorferi diacylglycerols to human T cells. Eur J Immunol. 2019 05; 49(5):737-746. PMID: 30854633.
    Citations: 4     Fields:    Translation:HumansCells
  19. Reinink P, Buter J, Mishra VK, Ishikawa E, Cheng TY, Willemsen PTJ, Porwollik S, Brennan PJ, Heinz E, Mayfield JA, Dougan G, van Els CA, Cerundolo V, Napolitani G, Yamasaki S, Minnaard AJ, McClelland M, Moody DB, Van Rhijn I. Discovery of Salmonella trehalose phospholipids reveals functional convergence with mycobacteria. J Exp Med. 2019 04 01; 216(4):757-771. PMID: 30804000.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  20. Shahine A, Reinink P, Reijneveld JF, Gras S, Holzheimer M, Cheng TY, Minnaard AJ, Altman JD, Lenz S, Prandi J, Kubler-Kielb J, Moody DB, Rossjohn J, Van Rhijn I. A T-cell receptor escape channel allows broad T-cell response to CD1b and membrane phospholipids. Nat Commun. 2019 01 04; 10(1):56. PMID: 30610190.
    Citations: 13     Fields:    Translation:HumansCells
  21. Wun KS, Reijneveld JF, Cheng TY, Ladell K, Uldrich AP, Le Nours J, Miners KL, McLaren JE, Grant EJ, Haigh OL, Watkins TS, Suliman S, Iwany S, Jimenez J, Calderon R, Tamara KL, Leon SR, Murray MB, Mayfield JA, Altman JD, Purcell AW, Miles JJ, Godfrey DI, Gras S, Price DA, Van Rhijn I, Moody DB, Rossjohn J. T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids. Nat Immunol. 2018 04; 19(4):397-406. PMID: 29531339.
    Citations: 21     Fields:    Translation:HumansCells
  22. James CA, Yu KKQ, Gilleron M, Prandi J, Yedulla VR, Moleda ZZ, Diamanti E, Khan M, Aggarwal VK, Reijneveld JF, Reinink P, Lenz S, Emerson RO, Scriba TJ, Souter MNT, Godfrey DI, Pellicci DG, Moody DB, Minnaard AJ, Seshadri C, Van Rhijn I. CD1b Tetramers Identify T Cells that Recognize Natural and Synthetic Diacylated Sulfoglycolipids from Mycobacterium tuberculosis. Cell Chem Biol. 2018 04 19; 25(4):392-402.e14. PMID: 29398561.
    Citations: 13     Fields:    Translation:HumansCells
  23. Gras S, Van Rhijn I, Shahine A, Le Nours J. Molecular recognition of microbial lipid-based antigens by T cells. Cell Mol Life Sci. 2018 05; 75(9):1623-1639. PMID: 29340708.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  24. Shahine A, Van Rhijn I, Cheng TY, Iwany S, Gras S, Moody DB, Rossjohn J. A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. Sci Immunol. 2017 10 20; 2(16). PMID: 29054999.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  25. Van Rhijn I, Iwany SK, Fodran P, Cheng TY, Gapin L, Minnaard AJ, Moody DB. CD1b-mycolic acid tetramers demonstrate T-cell fine specificity for mycobacterial lipid tails. Eur J Immunol. 2017 09; 47(9):1525-1534. PMID: 28665555.
    Citations: 23     Fields:    Translation:HumansCells
  26. Bagchi S, He Y, Zhang H, Cao L, Van Rhijn I, Moody DB, Gudjonsson JE, Wang CR. CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice. J Clin Invest. 2017 Jun 01; 127(6):2339-2352. PMID: 28463230.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  27. Cheng JM, Liu L, Pellicci DG, Reddiex SJ, Cotton RN, Cheng TY, Young DC, Van Rhijn I, Moody DB, Rossjohn J, Fairlie DP, Godfrey DI, Williams SJ. Total Synthesis of Mycobacterium tuberculosis Dideoxymycobactin-838 and Stereoisomers: Diverse CD1a-Restricted T Cells Display a Common Hierarchy of Lipopeptide Recognition. Chemistry. 2017 Jan 31; 23(7):1694-1701. PMID: 27925318.
    Citations: 5     Fields:    Translation:HumansCells
  28. Gras S, Van Rhijn I, Shahine A, Cheng TY, Bhati M, Tan LL, Halim H, Tuttle KD, Gapin L, Le Nours J, Moody DB, Rossjohn J. T cell receptor recognition of CD1b presenting a mycobacterial glycolipid. Nat Commun. 2016 10 27; 7:13257. PMID: 27807341.
    Citations: 33     Fields:    Translation:HumansCells
  29. Reinink P, Van Rhijn I. Mammalian CD1 and MR1 genes. Immunogenetics. 2016 Aug; 68(8):515-23. PMID: 27470004.
    Citations: 11     Fields:    Translation:HumansAnimals
  30. Van Rhijn I, van Berlo T, Hilmenyuk T, Cheng TY, Wolf BJ, Tatituri RV, Uldrich AP, Napolitani G, Cerundolo V, Altman JD, Willemsen P, Huang S, Rossjohn J, Besra GS, Brenner MB, Godfrey DI, Moody DB. Human autoreactive T cells recognize CD1b and phospholipids. Proc Natl Acad Sci U S A. 2016 Jan 12; 113(2):380-5. PMID: 26621732.
    Citations: 42     Fields:    Translation:HumansCells
  31. Van Rhijn I, Godfrey DI, Rossjohn J, Moody DB. Lipid and small-molecule display by CD1 and MR1. Nat Rev Immunol. 2015 Oct; 15(10):643-54. PMID: 26388332.
    Citations: 70     Fields:    Translation:HumansCells
  32. Van Rhijn I, Moody DB. Donor Unrestricted T Cells: A Shared Human T Cell Response. J Immunol. 2015 Sep 01; 195(5):1927-32. PMID: 26297792.
    Citations: 37     Fields:    Translation:HumansCells
  33. Nguyen TK, Reinink P, El Messlaki C, Im JS, Ercan A, Porcelli SA, Van Rhijn I. Correction: Expression Patterns of Bovine CD1 In Vivo and Assessment of the Specificities of the Anti-Bovine CD1 Antibodies. PLoS One. 2015; 10(6):e0129755. PMID: 26046785.
    Citations:    Fields:    
  34. Nguyen TK, Reinink P, El Messlaki C, Im JS, Ercan A, Porcelli SA, Van Rhijn I. Expression patterns of bovine CD1 in vivo and assessment of the specificities of the anti-bovine CD1 antibodies. PLoS One. 2015; 10(3):e0121923. PMID: 25815476.
    Citations: 5     Fields:    Translation:AnimalsCells
  35. Van Rhijn I, Moody DB. CD1 and mycobacterial lipids activate human T cells. Immunol Rev. 2015 Mar; 264(1):138-53. PMID: 25703557.
    Citations: 37     Fields:    Translation:HumansAnimalsCells
  36. van Schaik B, Klarenbeek P, Doorenspleet M, van Kampen A, Moody DB, de Vries N, Van Rhijn I. Discovery of invariant T cells by next-generation sequencing of the human TCR a-chain repertoire. J Immunol. 2014 Nov 15; 193(10):5338-44. PMID: 25339678.
    Citations: 11     Fields:    Translation:HumansCells
  37. Kawasaki N, Rillahan CD, Cheng TY, Van Rhijn I, Macauley MS, Moody DB, Paulson JC. Targeted delivery of mycobacterial antigens to human dendritic cells via Siglec-7 induces robust T cell activation. J Immunol. 2014 Aug 15; 193(4):1560-6. PMID: 25000981.
    Citations: 22     Fields:    Translation:HumansCells
  38. Van Rhijn I, Gherardin NA, Kasmar A, de Jager W, Pellicci DG, Kostenko L, Tan LL, Bhati M, Gras S, Godfrey DI, Rossjohn J, Moody DB. TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoire. J Immunol. 2014 May 01; 192(9):4054-60. PMID: 24683194.
    Citations: 38     Fields:    Translation:HumansCells
  39. de Jong A, Cheng TY, Huang S, Gras S, Birkinshaw RW, Kasmar AG, Van Rhijn I, Peña-Cruz V, Ruan DT, Altman JD, Rossjohn J, Moody DB. CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens. Nat Immunol. 2014 Feb; 15(2):177-85. PMID: 24362891.
    Citations: 81     Fields:    Translation:HumansCells
  40. Kasmar AG, Van Rhijn I, Magalhaes KG, Young DC, Cheng TY, Turner MT, Schiefner A, Kalathur RC, Wilson IA, Bhati M, Gras S, Birkinshaw RW, Tan LL, Rossjohn J, Shires J, Jakobsen S, Altman JD, Moody DB. Cutting Edge: CD1a tetramers and dextramers identify human lipopeptide-specific T cells ex vivo. J Immunol. 2013 Nov 01; 191(9):4499-503. PMID: 24089190.
    Citations: 39     Fields:    Translation:HumansCells
  41. Van Rhijn I, Kasmar A, de Jong A, Gras S, Bhati M, Doorenspleet ME, de Vries N, Godfrey DI, Altman JD, de Jager W, Rossjohn J, Moody DB. A conserved human T cell population targets mycobacterial antigens presented by CD1b. Nat Immunol. 2013 Jul; 14(7):706-13. PMID: 23727893.
    Citations: 111     Fields:    Translation:HumansCells
  42. López-Sagaseta J, Dulberger CL, Crooks JE, Parks CD, Luoma AM, McFedries A, Van Rhijn I, Saghatelian A, Adams EJ. The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins. Proc Natl Acad Sci U S A. 2013 May 07; 110(19):E1771-8. PMID: 23613577.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  43. Van Rhijn I, Ly D, Moody DB. CD1a, CD1b, and CD1c in immunity against mycobacteria. Adv Exp Med Biol. 2013; 783:181-97. PMID: 23468110.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  44. Seshadri C, Turner MT, Lewinsohn DM, Moody DB, Van Rhijn I. Lipoproteins are major targets of the polyclonal human T cell response to Mycobacterium tuberculosis. J Immunol. 2013 Jan 01; 190(1):278-84. PMID: 23197260.
    Citations: 11     Fields:    Translation:HumansCells
  45. Wang J, Guillaume J, Pauwels N, Van Calenbergh S, Van Rhijn I, Zajonc DM. Crystal structures of bovine CD1d reveal altered aGalCer presentation and a restricted A' pocket unable to bind long-chain glycolipids. PLoS One. 2012; 7(10):e47989. PMID: 23110152.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  46. Looringh van Beeck FA, Leegwater PA, Herrmann T, Broere F, Rutten VP, Willemse T, Van Rhijn I. Tandem repeats modify the structure of the canine CD1D gene. Anim Genet. 2013 Jun; 44(3):352-5. PMID: 22988997.
    Citations: 2     Fields:    Translation:AnimalsCells
  47. Nguyen TK, Koets AP, Vordermeier M, Jervis PJ, Cox LR, Graham SP, Santema WJ, Moody DB, van Calenbergh S, Zajonc DM, Besra GS, Van Rhijn I. The bovine CD1D gene has an unusual gene structure and is expressed but cannot present a-galactosylceramide with a C26 fatty acid. Int Immunol. 2013 Feb; 25(2):91-8. PMID: 22968995.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  48. Vrieling M, Santema W, Van Rhijn I, Rutten V, Koets A. ?d T cell homing to skin and migration to skin-draining lymph nodes is CCR7 independent. J Immunol. 2012 Jan 15; 188(2):578-84. PMID: 22156593.
    Citations: 19     Fields:    Translation:AnimalsCells
  49. Kasmar AG, van Rhijn I, Cheng TY, Turner M, Seshadri C, Schiefner A, Kalathur RC, Annand JW, de Jong A, Shires J, Leon L, Brenner M, Wilson IA, Altman JD, Moody DB. CD1b tetramers bind aß T cell receptors to identify a mycobacterial glycolipid-reactive T cell repertoire in humans. J Exp Med. 2011 Aug 29; 208(9):1741-7. PMID: 21807869.
    Citations: 72     Fields:    Translation:HumansCells
  50. Nguyen TK, Wieland W, Santema W, Hoeboer J, van Eden W, Rutten V, Koets A, Van Rhijn I. Immune response of cattle immunized with a conjugate of the glycolipid glucose monomycolate and protein. Vet Immunol Immunopathol. 2011 Aug 15; 142(3-4):265-70. PMID: 21640388.
    Citations: 3     Fields:    Translation:AnimalsCellsPHPublic Health
  51. de Jong A, Peña-Cruz V, Cheng TY, Clark RA, Van Rhijn I, Moody DB. CD1a-autoreactive T cells are a normal component of the human aß T cell repertoire. Nat Immunol. 2010 Dec; 11(12):1102-9. PMID: 21037579.
    Citations: 135     Fields:    Translation:HumansCells
  52. Girardi E, Wang J, Mac TT, Versluis C, Bhowruth V, Besra G, Heck AJ, Van Rhijn I, Zajonc DM. Crystal structure of bovine CD1b3 with endogenously bound ligands. J Immunol. 2010 Jul 01; 185(1):376-86. PMID: 20519644.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  53. Goldfinch N, Reinink P, Connelley T, Koets A, Morrison I, Van Rhijn I. Conservation of mucosal associated invariant T (MAIT) cells and the MR1 restriction element in ruminants, and abundance of MAIT cells in spleen. Vet Res. 2010 Sep-Oct; 41(5):62. PMID: 20507818.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  54. Van Rhijn I, Nguyen TK, Michel A, Cooper D, Govaerts M, Cheng TY, van Eden W, Moody DB, Coetzer JA, Rutten V, Koets AP. Low cross-reactivity of T-cell responses against lipids from Mycobacterium bovis and M. avium paratuberculosis during natural infection. Eur J Immunol. 2009 Nov; 39(11):3031-41. PMID: 19688747.
    Citations: 12     Fields:    Translation:AnimalsCells
  55. Maas M, Van Rhijn I, Allsopp MT, Rutten VP. Lion (Panthera leo) and cheetah (Acinonyx jubatus) IFN-gamma sequences. Vet Immunol Immunopathol. 2010 Apr 15; 134(3-4):296-8. PMID: 19913304.
    Citations:    Fields:    Translation:AnimalsCells
  56. Reinink P, Van Rhijn I. The bovine T cell receptor alpha/delta locus contains over 400 V genes and encodes V genes without CDR2. Immunogenetics. 2009 Jul; 61(7):541-9. PMID: 19568741.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  57. Kasmar A, Van Rhijn I, Moody DB. The evolved functions of CD1 during infection. Curr Opin Immunol. 2009 Aug; 21(4):397-403. PMID: 19541469.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  58. Nguyen TK, Koets AP, Santema WJ, van Eden W, Rutten VP, Van Rhijn I. The mycobacterial glycolipid glucose monomycolate induces a memory T cell response comparable to a model protein antigen and no B cell response upon experimental vaccination of cattle. Vaccine. 2009 Jul 30; 27(35):4818-25. PMID: 19538998.
    Citations: 12     Fields:    Translation:AnimalsCells
  59. Van Rhijn I, Young DC, De Jong A, Vazquez J, Cheng TY, Talekar R, Barral DC, Barral D, León L, Brenner MB, Katz JT, Riese R, Ruprecht RM, O'Connor PB, Costello CE, Porcelli SA, Briken V, Moody DB. CD1c bypasses lysosomes to present a lipopeptide antigen with 12 amino acids. J Exp Med. 2009 Jun 08; 206(6):1409-22. PMID: 19468063.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  60. Looringh van Beeck FA, Reinink P, Hermsen R, Zajonc DM, Laven MJ, Fun A, Troskie M, Schoemaker NJ, Morar D, Lenstra JA, Vervelde L, Rutten VP, van Eden W, Van Rhijn I. Functional CD1d and/or NKT cell invariant chain transcript in horse, pig, African elephant and guinea pig, but not in ruminants. Mol Immunol. 2009 Apr; 46(7):1424-31. PMID: 19185921.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  61. Hoek A, Rutten VP, Kool J, Arkesteijn GJ, Bouwstra RJ, Van Rhijn I, Koets AP. Subpopulations of bovine WC1(+) gammadelta T cells rather than CD4(+)CD25(high) Foxp3(+) T cells act as immune regulatory cells ex vivo. Vet Res. 2009 Jan-Feb; 40(1):6. PMID: 18928784.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  62. Looringh van Beeck FA, Zajonc DM, Moore PF, Schlotter YM, Broere F, Rutten VP, Willemse T, Van Rhijn I. Two canine CD1a proteins are differentially expressed in skin. Immunogenetics. 2008 Jun; 60(6):315-24. PMID: 18488214.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  63. Van Rhijn I, Godfroid J, Michel A, Rutten V. Bovine tuberculosis as a model for human tuberculosis: advantages over small animal models. Microbes Infect. 2008 Jun; 10(7):711-5. PMID: 18538612.
    Citations: 25     Fields:    Translation:HumansAnimals
  64. Van Rhijn I, Spiering R, Smits M, van Blokland MT, de Weger R, van Eden W, Rutten VP, Koets AP. Highly diverse TCR delta chain repertoire in bovine tissues due to the use of up to four D segments per delta chain. Mol Immunol. 2007 May; 44(12):3155-61. PMID: 17418895.
    Citations: 8     Fields:    Translation:AnimalsCells
  65. Van Rhijn I, Rutten VPMG, Charleston B, Smits M, van Eden W, Koets AP. Massive, sustained ?d T cell migration from the bovine skin in vivo. J Leukoc Biol. 2007 Apr; 81(4):968-973. PMID: 29350847.
    Citations: 1     Fields:    
  66. Van Rhijn I, Rutten VP, Charleston B, Smits M, van Eden W, Koets AP. Massive, sustained gammadelta T cell migration from the bovine skin in vivo. J Leukoc Biol. 2007 Apr; 81(4):968-73. PMID: 17234682.
    Citations: 10     Fields:    Translation:AnimalsCells
  67. Cheng TY, Relloso M, Van Rhijn I, Young DC, Besra GS, Briken V, Zajonc DM, Wilson IA, Porcelli S, Moody DB. Role of lipid trimming and CD1 groove size in cellular antigen presentation. EMBO J. 2006 Jul 12; 25(13):2989-99. PMID: 16794581.
    Citations: 24     Fields:    Translation:HumansCells
  68. Van Rhijn I, Koets AP, Im JS, Piebes D, Reddington F, Besra GS, Porcelli SA, van Eden W, Rutten VP. The bovine CD1 family contains group 1 CD1 proteins, but no functional CD1d. J Immunol. 2006 Apr 15; 176(8):4888-93. PMID: 16585584.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  69. Van Rhijn I, Zajonc DM, Wilson IA, Moody DB. T-cell activation by lipopeptide antigens. Curr Opin Immunol. 2005 Jun; 17(3):222-9. PMID: 15886110.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  70. Van Rhijn I, Young DC, Im JS, Levery SB, Illarionov PA, Besra GS, Porcelli SA, Gumperz J, Cheng TY, Moody DB. CD1d-restricted T cell activation by nonlipidic small molecules. Proc Natl Acad Sci U S A. 2004 Sep 14; 101(37):13578-83. PMID: 15342907.
    Citations: 50     Fields:    Translation:HumansCells
  71. Van Rhijn I, Logtenberg T, Ang CW, Van den Berg LH. Gammadelta T cell non-responsiveness in Campylobacter jejuni-associated Guillain-Barré syndrome patients. Neurology. 2003 Oct 14; 61(7):994-6. PMID: 14557578.
    Citations: 2     Fields:    Translation:HumansCells
  72. Van Rhijn I, Van den Berg LH, Ang CW, Admiraal J, Logtenberg T. Expansion of human gammadelta T cells after in vitro stimulation with Campylobacter jejuni. Int Immunol. 2003 Mar; 15(3):373-82. PMID: 12618481.
    Citations: 4     Fields:    Translation:HumansCells
  73. Van Rhijn I, Bleumink-Pluym NM, Van Putten JP, Van den Berg LH. Campylobacter DNA is present in circulating myelomonocytic cells of healthy persons and in persons with Guillain-Barré syndrome. J Infect Dis. 2002 Jan 15; 185(2):262-5. PMID: 11807702.
    Citations: 3     Fields:    Translation:HumansCells
  74. Van Rhijn I, Van den Berg LH, Bosboom WM, Otten HG, Logtenberg T. Expression of accessory molecules for T-cell activation in peripheral nerve of patients with CIDP and vasculitic neuropathy. Brain. 2000 Oct; 123 ( Pt 10):2020-9. PMID: 11004119.
    Citations: 11     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.