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Robert S. Langer, SC.D.

Title
Institution
Department
Address
Phone
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Other Positions
Title
Institution
Department

Mentoring
Development of a Chlorhexidine Polymer Drug Delivery Vehicle fo rthe Treatment of Periodontal Disease
Part Time/Continuation, 09/01/99 - 06/30/00
Polyorthoester-Based Microspheres as Potentail Endosomolytic Transfection Modulators
Summer, 05/22/00 - 08/31/00

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01EB016101 (LANGER, ROBERT SAMUEL) Apr 1, 2013 - Feb 28, 2018
    NIH/NIBIB
    A New Device for Electrical & Chemical Modulation of Pathological Neural Activity
    Role: Co-Principal Investigator
  2. U54CA151884 (LANGER, ROBERT SAMUEL) Sep 1, 2010 - Jul 31, 2015
    NIH/NCI
    MIT-Harvard Center of Cancer Nanotechnology Excellence
    Role: Principal Investigator
  3. RC1DE020761 (ANDERSON, DANIEL G) Mar 9, 2010 - Sep 30, 2013
    NIH/NIDCR
    Human Pluripotent Stem Cell Differentiation with Defined O2 &Protein Engagement
    Role: Co-Principal Investigator
  4. RC1EB011187 (ANDERSON, DANIEL G) Sep 30, 2009 - Aug 31, 2011
    NIH/NIBIB
    High throughput cell reprogramming by microfluidic jet injection
    Role: Co-Principal Investigator
  5. U54CA119349 (LANGER, ROBERT SAMUEL) Sep 30, 2005 - Aug 31, 2011
    NIH/NCI
    The MIT-Harvard Center of Cancer Nanotechnology Excelle*
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Mead BE, Ordovas-Montanes J, Braun AP, Levy LE, Bhargava P, Szucs MJ, Ammendolia DA, MacMullan MA, Yin X, Hughes TK, Wadsworth MH, Ahmad R, Rakoff-Nahoum S, Carr SA, Langer R, Collins JJ, Shalek AK, Karp JM. Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types. BMC Biol. 2018 Jun 05; 16(1):62. PMID: 29871632.
    View in: PubMed
  2. Schneider C, Langer R, Loveday D, Hair D. Corrigendum to "Applications of ethylene vinyl acetate copolymers (EVA) in drug delivery systems" [J. Control. Release 262(2017) 284-295]. J Control Release. 2018 May 28; 278:156-158. PMID: 29685764.
    View in: PubMed
  3. Mimee M, Nadeau P, Hayward A, Carim S, Flanagan S, Jerger L, Collins J, McDonnell S, Swartwout R, Citorik RJ, Bulovic V, Langer R, Traverso G, Chandrakasan AP, Lu TK. An ingestible bacterial-electronic system to monitor gastrointestinal health. Science. 2018 05 25; 360(6391):915-918. PMID: 29798884.
    View in: PubMed
  4. Tzeng SY, McHugh KJ, Behrens AM, Rose S, Sugarman JL, Ferber S, Langer R, Jaklenec A. Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response. Proc Natl Acad Sci U S A. 2018 Jun 05; 115(23):E5269-E5278. PMID: 29784798.
    View in: PubMed
  5. Ferber S, Behrens AM, McHugh KJ, Rosenberg EM, Linehan AR, Sugarman JL, Jayawardena HSN, Langer R, Jaklenec A. Evaporative Cooling Hydrogel Packaging for Storing Biologics Outside of the Cold Chain. Adv Healthc Mater. 2018 May 07; e1800220. PMID: 29732715.
    View in: PubMed
  6. Fenton OS, Olafson KN, Pillai PS, Mitchell MJ, Langer R. Advances in Biomaterials for Drug Delivery. Adv Mater. 2018 May 07; e1705328. PMID: 29736981.
    View in: PubMed
  7. van der Valk DC, van der Ven CFT, Blaser MC, Grolman JM, Wu PJ, Fenton OS, Lee LH, Tibbitt MW, Andresen JL, Wen JR, Ha AH, Buffolo F, van Mil A, Bouten CVC, Body SC, Mooney DJ, Sluijter JPG, Aikawa M, Hjortnaes J, Langer R, Aikawa E. Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics. Nanomaterials (Basel). 2018 May 03; 8(5). PMID: 29751516.
    View in: PubMed
  8. Jonas AM, Glinel K, Behrens A, Anselmo AC, Langer RS, Jaklenec A. Controlling the Growth of Staphylococcus epidermidis by Layer-By-Layer Encapsulation. ACS Appl Mater Interfaces. 2018 May 16; 10(19):16250-16259. PMID: 29693369.
    View in: PubMed
  9. DiCiccio AM, Lee YL, Glettig DL, Walton ESE, de la Serna EL, Montgomery VA, Grant TM, Langer R, Traverso G. Caffeine-catalyzed gels. Biomaterials. 2018 Jul; 170:127-135. PMID: 29660635.
    View in: PubMed
  10. Ayoob AM, Peppi M, Tandon V, Langer R, Borenstein JT. A fluorescence-based imaging approach to pharmacokinetic analysis of intracochlear drug delivery. Hear Res. 2018 Apr 05. PMID: 29661614.
    View in: PubMed
  11. Ragelle H, Tibbitt MW, Wu SY, Castillo MA, Cheng GZ, Gangadharan SP, Anderson DG, Cima MJ, Langer R. Surface tension-assisted additive manufacturing. Nat Commun. 2018 Mar 22; 9(1):1184. PMID: 29567939.
    View in: PubMed
  12. Kang SY, Ji Z, Tseng LF, Turner SA, Villanueva DA, Johnson R, Albano A, Langer R. Design and Synthesis of Waterborne Polyurethanes. Adv Mater. 2018 May; 30(18):e1706237. PMID: 29543353.
    View in: PubMed
  13. Traverso G, Kirtane AR, Schoellhammer CM, Langer R. Convergence for Translation: Drug-Delivery Research in Multidisciplinary Teams. Angew Chem Int Ed Engl. 2018 Apr 09; 57(16):4156-4163. PMID: 29520902.
    View in: PubMed
  14. McHugh KJ, Jing L, Behrens AM, Jayawardena S, Tang W, Gao M, Langer R, Jaklenec A. Biocompatible Semiconductor Quantum Dots as Cancer Imaging Agents. Adv Mater. 2018 May; 30(18):e1706356. PMID: 29468747.
    View in: PubMed
  15. Delcassian D, Patel AK, Cortinas AB, Langer R. Drug delivery across length scales. J Drug Target. 2018 Feb 20; 1-15. PMID: 29415575.
    View in: PubMed
  16. Guimarães PPG, Gaglione S, Sewastianik T, Carrasco RD, Langer R, Mitchell MJ. Nanoparticles for Immune Cytokine TRAIL-Based Cancer Therapy. ACS Nano. 2018 Feb 27; 12(2):912-931. PMID: 29378114.
    View in: PubMed
  17. Yin H, Song CQ, Suresh S, Kwan SY, Wu Q, Walsh S, Ding J, Bogorad RL, Zhu LJ, Wolfe SA, Koteliansky V, Xue W, Langer R, Anderson DG. Partial DNA-guided Cas9 enables genome editing with reduced off-target activity. Nat Chem Biol. 2018 Mar; 14(3):311-316. PMID: 29377001.
    View in: PubMed
  18. Dagdeviren C, Ramadi KB, Joe P, Spencer K, Schwerdt HN, Shimazu H, Delcasso S, Amemori KI, Nunez-Lopez C, Graybiel AM, Cima MJ, Langer R. Miniaturized neural system for chronic, local intracerebral drug delivery. Sci Transl Med. 2018 Jan 24; 10(425). PMID: 29367347.
    View in: PubMed
  19. Kirtane AR, Abouzid O, Minahan D, Bensel T, Hill AL, Selinger C, Bershteyn A, Craig M, Mo SS, Mazdiyasni H, Cleveland C, Rogner J, Lee YL, Booth L, Javid F, Wu SJ, Grant T, Bellinger AM, Nikolic B, Hayward A, Wood L, Eckhoff PA, Nowak MA, Langer R, Traverso G. Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy. Nat Commun. 2018 01 09; 9(1):2. PMID: 29317618.
    View in: PubMed
  20. Mikulskis P, Hook A, Dundas AA, Irvine D, Sanni O, Anderson D, Langer R, Alexander MR, Williams P, Winkler DA. Prediction of Broad-Spectrum Pathogen Attachment to Coating Materials for Biomedical Devices. ACS Appl Mater Interfaces. 2018 Jan 10; 10(1):139-149. PMID: 29191009.
    View in: PubMed
  21. Bisso PW, Tai M, Katepalli H, Bertrand N, Blankschtein D, Langer R. Molecular Rotors for Universal Quantitation of Nanoscale Hydrophobic Interfaces in Microplate Format. Nano Lett. 2018 Jan 10; 18(1):618-628. PMID: 29244511.
    View in: PubMed
  22. Bakh NA, Cortinas AB, Weiss MA, Langer RS, Anderson DG, Gu Z, Dutta S, Strano MS. Erratum: Glucose-responsive insulin by molecular and physical design. Nat Chem. 2017 Dec 19; 10(1):109. PMID: 29256502.
    View in: PubMed
  23. Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera F, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH. Corrigendum: In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nat Biotechnol. 2017 Dec 08; 35(12):1211. PMID: 29220013.
    View in: PubMed
  24. Kauffman KJ, Oberli MA, Dorkin JR, Hurtado JE, Kaczmarek JC, Bhadani S, Wyckoff J, Langer R, Jaklenec A, Anderson DG. Rapid, Single-Cell Analysis and Discovery of Vectored mRNA Transfection In Vivo with a loxP-Flanked tdTomato Reporter Mouse. Mol Ther Nucleic Acids. 2018 Mar 02; 10:55-63. PMID: 29499956.
    View in: PubMed
  25. Schwerdt HN, Shimazu H, Amemori KI, Amemori S, Tierney PL, Gibson DJ, Hong S, Yoshida T, Langer R, Cima MJ, Graybiel AM. Long-term dopamine neurochemical monitoring in primates. Proc Natl Acad Sci U S A. 2017 12 12; 114(50):13260-13265. PMID: 29158415.
    View in: PubMed
  26. Sharma U, Concagh D, Core L, Kuang Y, You C, Pham Q, Zugates G, Busold R, Webber S, Merlo J, Langer R, Whitesides GM, Palasis M. The development of bioresorbable composite polymeric implants with high mechanical strength. Nat Mater. 2018 Jan; 17(1):96-103. PMID: 29180778.
    View in: PubMed
  27. Yin H, Song CQ, Suresh S, Wu Q, Walsh S, Rhym LH, Mintzer E, Bolukbasi MF, Zhu LJ, Kauffman K, Mou H, Oberholzer A, Ding J, Kwan SY, Bogorad RL, Zatsepin T, Koteliansky V, Wolfe SA, Xue W, Langer R, Anderson DG. Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing. Nat Biotechnol. 2017 Dec; 35(12):1179-1187. PMID: 29131148.
    View in: PubMed
  28. Tong Z, Martyn K, Yang A, Yin X, Mead BE, Joshi N, Sherman NE, Langer RS, Karp JM. Towards a defined ECM and small molecule based monolayer culture system for the expansion of mouse and human intestinal stem cells. Biomaterials. 2018 Feb; 154:60-73. PMID: 29120819.
    View in: PubMed
  29. Schoellhammer CM, Chen Y, Cleveland C, Minahan D, Bensel T, Park JY, Saxton S, Lee YL, Booth L, Langer R, Traverso G. Defining optimal permeant characteristics for ultrasound-mediated gastrointestinal delivery. J Control Release. 2017 Dec 28; 268:113-119. PMID: 29051063.
    View in: PubMed
  30. Spencer KC, Sy JC, Ramadi KB, Graybiel AM, Langer R, Cima MJ. Erratum: Characterization of Mechanically Matched Hydrogel Coatings to Improve the Biocompatibility of Neural Implants. Sci Rep. 2017 Oct 09; 7(1):12812. PMID: 28993678.
    View in: PubMed
  31. Bertrand N, Grenier P, Mahmoudi M, Lima EM, Appel EA, Dormont F, Lim JM, Karnik R, Langer R, Farokhzad OC. Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics. Nat Commun. 2017 10 03; 8(1):777. PMID: 28974673.
    View in: PubMed
  32. Aday S, Zoldan J, Besnier M, Carreto L, Saif J, Fernandes R, Santos T, Bernardino L, Langer R, Emanueli C, Ferreira L. Synthetic microparticles conjugated with VEGF165 improve the survival of endothelial progenitor cells via microRNA-17 inhibition. Nat Commun. 2017 09 29; 8(1):747. PMID: 28963481.
    View in: PubMed
  33. Bakh NA, Cortinas AB, Weiss MA, Langer RS, Anderson DG, Gu Z, Dutta S, Strano MS. Glucose-responsive insulin by molecular and physical design. Nat Chem. 2017 09 22; 9(10):937-943. PMID: 28937662.
    View in: PubMed
  34. McHugh KJ, Nguyen TD, Linehan AR, Yang D, Behrens AM, Rose S, Tochka ZL, Tzeng SY, Norman JJ, Anselmo AC, Xu X, Tomasic S, Taylor MA, Lu J, Guarecuco R, Langer R, Jaklenec A. Fabrication of fillable microparticles and other complex 3D microstructures. Science. 2017 09 15; 357(6356):1138-1142. PMID: 28912242.
    View in: PubMed
  35. Mahmoudi M, Yu M, Serpooshan V, Wu JC, Langer R, Lee RT, Karp JM, Farokhzad OC. Multiscale technologies for treatment of ischemic cardiomyopathy. Nat Nanotechnol. 2017 Sep 06; 12(9):845-855. PMID: 28875984.
    View in: PubMed
  36. Rwei AY, Paris JL, Wang B, Wang W, Axon CD, Vallet-Regí M, Langer R, Kohane DS. Ultrasound-triggered local anaesthesia. Nat Biomed Eng. 2017; 1:644-653. PMID: 29152410.
    View in: PubMed
  37. Schneider C, Langer R, Loveday D, Hair D. Applications of ethylene vinyl acetate copolymers (EVA) in drug delivery systems. J Control Release. 2017 Sep 28; 262:284-295. PMID: 28789964.
    View in: PubMed
  38. Caffarel-Salvador E, Abramson A, Langer R, Traverso G. Oral delivery of biologics using drug-device combinations. Curr Opin Pharmacol. 2017 10; 36:8-13. PMID: 28779684.
    View in: PubMed
  39. Yang NJ, Kauke MJ, Sun F, Yang LF, Maass KF, Traxlmayr MW, Yu Y, Xu Y, Langer RS, Anderson DG, Wittrup KD. Cytosolic delivery of siRNA by ultra-high affinity dsRNA binding proteins. Nucleic Acids Res. 2017 Jul 27; 45(13):7602-7614. PMID: 28641400.
    View in: PubMed
  40. Liu J, Pang Y, Zhang S, Cleveland C, Yin X, Booth L, Lin J, Lucy Lee YA, Mazdiyasni H, Saxton S, Kirtane AR, Erlach TV, Rogner J, Langer R, Traverso G. Triggerable tough hydrogels for gastric resident dosage forms. Nat Commun. 2017 07 25; 8(1):124. PMID: 28743858.
    View in: PubMed
  41. Jung K, Heishi T, Khan OF, Kowalski PS, Incio J, Rahbari NN, Chung E, Clark JW, Willett CG, Luster AD, Yun SH, Langer R, Anderson DG, Padera TP, Jain RK, Fukumura D. Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy. J Clin Invest. 2017 Aug 01; 127(8):3039-3051. PMID: 28691930.
    View in: PubMed
  42. Yu D, Khan OF, Suvà ML, Dong B, Panek WK, Xiao T, Wu M, Han Y, Ahmed AU, Balyasnikova IV, Zhang HF, Sun C, Langer R, Anderson DG, Lesniak MS. Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression. Proc Natl Acad Sci U S A. 2017 07 25; 114(30):E6147-E6156. PMID: 28696296.
    View in: PubMed
  43. Fenton OS, Kauffman KJ, Kaczmarek JC, McClellan RL, Jhunjhunwala S, Tibbitt MW, Zeng MD, Appel EA, Dorkin JR, Mir FF, Yang JH, Oberli MA, Heartlein MW, DeRosa F, Langer R, Anderson DG. Synthesis and Biological Evaluation of Ionizable Lipid Materials for the In Vivo Delivery of Messenger RNA to B Lymphocytes. Adv Mater. 2017 Sep; 29(33). PMID: 28681930.
    View in: PubMed
  44. Guarecuco R, Lu J, McHugh KJ, Norman JJ, Thapa LS, Lydon E, Langer R, Jaklenec A. Immunogenicity of pulsatile-release PLGA microspheres for single-injection vaccination. Vaccine. 2018 05 24; 36(22):3161-3168. PMID: 28625520.
    View in: PubMed
  45. Giwa S, Lewis JK, Alvarez L, Langer R, Roth AE, Church GM, Markmann JF, Sachs DH, Chandraker A, Wertheim JA, Rothblatt M, Boyden ES, Eidbo E, Lee WPA, Pomahac B, Brandacher G, Weinstock DM, Elliott G, Nelson D, Acker JP, Uygun K, Schmalz B, Weegman BP, Tocchio A, Fahy GM, Storey KB, Rubinsky B, Bischof J, Elliott JAW, Woodruff TK, Morris GJ, Demirci U, Brockbank KGM, Woods EJ, Ben RN, Baust JG, Gao D, Fuller B, Rabin Y, Kravitz DC, Taylor MJ, Toner M. The promise of organ and tissue preservation to transform medicine. Nat Biotechnol. 2017 06 07; 35(6):530-542. PMID: 28591112.
    View in: PubMed
  46. Zwang Y, Jonas O, Chen C, Rinne ML, Doench JG, Piccioni F, Tan L, Huang HT, Wang J, Ham YJ, O'Connell J, Bhola P, Doshi M, Whitman M, Cima M, Letai A, Root DE, Langer RS, Gray N, Hahn WC. Synergistic interactions with PI3K inhibition that induce apoptosis. Elife. 2017 05 31; 6. PMID: 28561737.
    View in: PubMed
  47. Spencer KC, Sy JC, Ramadi KB, Graybiel AM, Langer R, Cima MJ. Characterization of Mechanically Matched Hydrogel Coatings to Improve the Biocompatibility of Neural Implants. Sci Rep. 2017 May 16; 7(1):1952. PMID: 28512291.
    View in: PubMed
  48. Roper J, Tammela T, Cetinbas NM, Akkad A, Roghanian A, Rickelt S, Almeqdadi M, Wu K, Oberli MA, Sánchez-Rivera FJ, Park YK, Liang X, Eng G, Taylor MS, Azimi R, Kedrin D, Neupane R, Beyaz S, Sicinska ET, Suarez Y, Yoo J, Chen L, Zukerberg L, Katajisto P, Deshpande V, Bass AJ, Tsichlis PN, Lees J, Langer R, Hynes RO, Chen J, Bhutkar A, Jacks T, Yilmaz ÖH. In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nat Biotechnol. 2017 06; 35(6):569-576. PMID: 28459449.
    View in: PubMed
  49. Abid A, O'Brien JM, Bensel T, Cleveland C, Booth L, Smith BR, Langer R, Traverso G. Wireless Power Transfer to Millimeter-Sized Gastrointestinal Electronics Validated in a Swine Model. Sci Rep. 2017 Apr 27; 7:46745. PMID: 28447624.
    View in: PubMed
  50. Cha Y, Han MJ, Cha HJ, Zoldan J, Burkart A, Jung JH, Jang Y, Kim CH, Jeong HC, Kim BG, Langer R, Kahn CR, Guarente L, Kim KS. Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c-SIRT2 axis. Nat Cell Biol. 2017 May; 19(5):445-456. PMID: 28436968.
    View in: PubMed
  51. Tibbitt MW, Langer R. Living Biomaterials. Acc Chem Res. 2017 Mar 21; 50(3):508-513. PMID: 28945422.
    View in: PubMed
  52. Mitchell MJ, Webster J, Chung A, Guimarães PP, Khan OF, Langer R. Polymeric mechanical amplifiers of immune cytokine-mediated apoptosis. Nat Commun. 2017 Mar 20; 8:14179. PMID: 28317839.
    View in: PubMed
  53. Doloff JC, Veiseh O, Vegas AJ, Tam HH, Farah S, Ma M, Li J, Bader A, Chiu A, Sadraei A, Aresta-Dasilva S, Griffin M, Jhunjhunwala S, Webber M, Siebert S, Tang K, Chen M, Langan E, Dholokia N, Thakrar R, Qi M, Oberholzer J, Greiner DL, Langer R, Anderson DG. Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates. Nat Mater. 2017 Jun; 16(6):671-680. PMID: 28319612.
    View in: PubMed
  54. Yesilyurt V, Ayoob AM, Appel EA, Borenstein JT, Langer R, Anderson DG. Mixed Reversible Covalent Crosslink Kinetics Enable Precise, Hierarchical Mechanical Tuning of Hydrogel Networks. Adv Mater. 2017 May; 29(19). PMID: 28295624.
    View in: PubMed
  55. Schwerdt HN, Kim MJ, Amemori S, Homma D, Yoshida T, Shimazu H, Yerramreddy H, Karasan E, Langer R, Graybiel AM, Cima MJ. Subcellular probes for neurochemical recording from multiple brain sites. Lab Chip. 2017 03 14; 17(6):1104-1115. PMID: 28233001.
    View in: PubMed
  56. Ding X, Stewart M, Sharei A, Weaver JC, Langer RS, Jensen KF. High-throughput Nuclear Delivery and Rapid Expression of DNA via Mechanical and Electrical Cell-Membrane Disruption. Nat Biomed Eng. 2017; 1. PMID: 28932622.
    View in: PubMed
  57. Ragelle H, Naba A, Larson BL, Zhou F, Prijic M, Whittaker CA, Del Rosario A, Langer R, Hynes RO, Anderson DG. Comprehensive proteomic characterization of stem cell-derived extracellular matrices. Biomaterials. 2017 06; 128:147-159. PMID: 28327460.
    View in: PubMed
  58. McLean WJ, Yin X, Lu L, Lenz DR, McLean D, Langer R, Karp JM, Edge ASB. Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory Hair Cells. Cell Rep. 2017 02 21; 18(8):1917-1929. PMID: 28228258.
    View in: PubMed
  59. Dahlman JE, Kauffman KJ, Xing Y, Shaw TE, Mir FF, Dlott CC, Langer R, Anderson DG, Wang ET. Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics. Proc Natl Acad Sci U S A. 2017 02 21; 114(8):2060-2065. PMID: 28167778.
    View in: PubMed
  60. Nadeau P, El-Damak D, Glettig D, Kong YL, Mo S, Cleveland C, Booth L, Roxhed N, Langer R, Chandrakasan AP, Traverso G. Prolonged energy harvesting for ingestible devices. Nat Biomed Eng. 2017; 1. PMID: 28458955.
    View in: PubMed
  61. van der Ven CF, Wu PJ, Tibbitt MW, van Mil A, Sluijter JP, Langer R, Aikawa E. In vitro 3D model and miRNA drug delivery to target calcific aortic valve disease. Clin Sci (Lond). 2017 Feb 01; 131(3):181-195. PMID: 28057890.
    View in: PubMed
  62. Slotkin JR, Pritchard CD, Luque B, Ye J, Layer RT, Lawrence MS, O'Shea TM, Roy RR, Zhong H, Vollenweider I, Edgerton VR, Courtine G, Woodard EJ, Langer R. Biodegradable scaffolds promote tissue remodeling and functional improvement in non-human primates with acute spinal cord injury. Biomaterials. 2017 04; 123:63-76. PMID: 28167393.
    View in: PubMed
  63. Schoellhammer CM, Lauwers GY, Goettel JA, Oberli MA, Cleveland C, Park JY, Minahan D, Chen Y, Anderson DG, Jaklenec A, Snapper SB, Langer R, Traverso G. Ultrasound-Mediated Delivery of RNA to Colonic Mucosa of Live Mice. Gastroenterology. 2017 04; 152(5):1151-1160. PMID: 28088460.
    View in: PubMed
  64. Davidson SM, Jonas O, Keibler MA, Hou HW, Luengo A, Mayers JR, Wyckoff J, Del Rosario AM, Whitman M, Chin CR, Condon KJ, Lammers A, Kellersberger KA, Stall BK, Stephanopoulos G, Bar-Sagi D, Han J, Rabinowitz JD, Cima MJ, Langer R, Vander Heiden MG. Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors. Nat Med. 2017 Feb; 23(2):235-241. PMID: 28024083.
    View in: PubMed
  65. Luo X, Wang W, Dorkin JR, Veiseh O, Chang PH, Abutbul-Ionita I, Danino D, Langer R, Anderson DG, Dong Y. Poly(glycoamidoamine) brush nanomaterials for systemic siRNA delivery in vivo. Biomater Sci. 2016 Dec 20; 5(1):38-40. PMID: 27921096.
    View in: PubMed
  66. Yesilyurt V, Veiseh O, Doloff JC, Li J, Bose S, Xie X, Bader AR, Chen M, Webber MJ, Vegas AJ, Langer R, Anderson DG. A Facile and Versatile Method to Endow Biomaterial Devices with Zwitterionic Surface Coatings. Adv Healthc Mater. 2017 Feb; 6(4). PMID: 27976536.
    View in: PubMed
  67. Langer R, Basu A, Domb AJ. Special issue: Polylactide (PLA) Based Biopolymers. Adv Drug Deliv Rev. 2016 Dec 15; 107:1-2. PMID: 27938692.
    View in: PubMed
  68. Zugates GT, Peng W, Zumbuehl A, Jhunjhunwala S, Huang YH, Langer R, Sawicki JA, Anderson DG. Rapid Optimization of Gene Delivery by Parallel End-modification of Poly(ß-amino ester)s. Mol Ther. 2007 Jul; 15(7):1306-1312. PMID: 28182918.
    View in: PubMed
  69. Oberli MA, Reichmuth AM, Dorkin JR, Mitchell MJ, Fenton OS, Jaklenec A, Anderson DG, Langer R, Blankschtein D. Lipid Nanoparticle Assisted mRNA Delivery for Potent Cancer Immunotherapy. Nano Lett. 2017 03 08; 17(3):1326-1335. PMID: 28273716.
    View in: PubMed
  70. Webber MJ, Appel EA, Vinciguerra B, Cortinas AB, Thapa LS, Jhunjhunwala S, Isaacs L, Langer R, Anderson DG. Supramolecular PEGylation of biopharmaceuticals. Proc Natl Acad Sci U S A. 2016 12 13; 113(50):14189-14194. PMID: 27911829.
    View in: PubMed
  71. Bellinger AM, Jafari M, Grant TM, Zhang S, Slater HC, Wenger EA, Mo S, Lee YL, Mazdiyasni H, Kogan L, Barman R, Cleveland C, Booth L, Bensel T, Minahan D, Hurowitz HM, Tai T, Daily J, Nikolic B, Wood L, Eckhoff PA, Langer R, Traverso G. Oral, ultra-long-lasting drug delivery: Application toward malaria elimination goals. Sci Transl Med. 2016 11 16; 8(365):365ra157. PMID: 27856796.
    View in: PubMed
  72. Kirtane AR, Langer R, Traverso G. Past, Present, and Future Drug Delivery Systems for Antiretrovirals. J Pharm Sci. 2016 12; 105(12):3471-3482. PMID: 27771050.
    View in: PubMed
  73. Ragelle H, Danhier F, Préat V, Langer R, Anderson DG. Nanoparticle-based drug delivery systems: a commercial and regulatory outlook as the field matures. Expert Opin Drug Deliv. 2017 07; 14(7):851-864. PMID: 27730820.
    View in: PubMed
  74. Stewart MP, Sharei A, Ding X, Sahay G, Langer R, Jensen KF. In vitro and ex vivo strategies for intracellular delivery. Nature. 2016 10 13; 538(7624):183-192. PMID: 27734871.
    View in: PubMed
  75. Tam HH, Melo MB, Kang M, Pelet JM, Ruda VM, Foley MH, Hu JK, Kumari S, Crampton J, Baldeon AD, Sanders RW, Moore JP, Crotty S, Langer R, Anderson DG, Chakraborty AK, Irvine DJ. Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination. Proc Natl Acad Sci U S A. 2016 10 25; 113(43):E6639-E6648. PMID: 27702895.
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  76. Anselmo AC, McHugh KJ, Webster J, Langer R, Jaklenec A. Layer-by-Layer Encapsulation of Probiotics for Delivery to the Microbiome. Adv Mater. 2016 Nov; 28(43):9486-9490. PMID: 27616140.
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  77. Yun S, Budatha M, Dahlman JE, Coon BG, Cameron RT, Langer R, Anderson DG, Baillie G, Schwartz MA. Interaction between integrin a5 and PDE4D regulates endothelial inflammatory signalling. Nat Cell Biol. 2016 10; 18(10):1043-53. PMID: 27595237.
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  78. Saung MT, Sharei A, Adalsteinsson VA, Cho N, Kamath T, Ruiz C, Kirkpatrick J, Patel N, Mino-Kenudson M, Thayer SP, Langer R, Jensen KF, Liss AS, Love JC. A Size-Selective Intracellular Delivery Platform. Small. 2016 Sep 04. PMID: 27594517.
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  79. Khademhosseini A, Langer R. A decade of progress in tissue engineering. Nat Protoc. 2016 Oct; 11(10):1775-81. PMID: 27583639.
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  80. Adlington K, Nguyen NT, Eaves E, Yang J, Chang CY, Li J, Gower AL, Stimpson A, Anderson DG, Langer R, Davies MC, Hook AL, Williams P, Alexander MR, Irvine DJ. Application of Targeted Molecular and Material Property Optimization to Bacterial Attachment-Resistant (Meth)acrylate Polymers. Biomacromolecules. 2016 09 12; 17(9):2830-8. PMID: 27461341.
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  81. Dong Y, Wang W, Veiseh O, Appel EA, Xue K, Webber MJ, Tang BC, Yang XW, Weir GC, Langer R, Anderson DG. Injectable and Glucose-Responsive Hydrogels Based on Boronic Acid-Glucose Complexation. Langmuir. 2016 08 30; 32(34):8743-7. PMID: 27455412.
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  82. Hammad M, Rao W, Smith JG, Anderson DG, Langer R, Young LE, Barrett DA, Davies MC, Denning C, Alexander MR. Identification of polymer surface adsorbed proteins implicated in pluripotent human embryonic stem cell expansion. Biomater Sci. 2016 Aug 16; 4(9):1381-91. PMID: 27466628.
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  83. Chertok B, Langer R, Anderson DG. Spatial Control of Gene Expression by Nanocarriers Using Heparin Masking and Ultrasound-Targeted Microbubble Destruction. ACS Nano. 2016 Aug 23; 10(8):7267-78. PMID: 27472268.
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  84. Detappe A, Kunjachan S, Sancey L, Motto-Ros V, Biancur D, Drane P, Guieze R, Makrigiorgos GM, Tillement O, Langer R, Berbeco R. Advanced multimodal nanoparticles delay tumor progression with clinical radiation therapy. J Control Release. 2016 09 28; 238:103-113. PMID: 27423325.
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  85. Lee HC, Ahsen OO, Liang K, Wang Z, Cleveland C, Booth L, Potsaid B, Jayaraman V, Cable AE, Mashimo H, Langer R, Traverso G, Fujimoto JG. Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter. Biomed Opt Express. 2016 Aug 01; 7(8):2927-42. PMID: 27570688; PMCID: PMC4986804.
  86. Chahal JS, Khan OF, Cooper CL, McPartlan JS, Tsosie JK, Tilley LD, Sidik SM, Lourido S, Langer R, Bavari S, Ploegh HL, Anderson DG. Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose. Proc Natl Acad Sci U S A. 2016 07 19; 113(29):E4133-42. PMID: 27382155; PMCID: PMC4961123 [Available on 01/19/17].
  87. Kanasty RL, Vegas AJ, Ceo LM, Maier M, Charisse K, Nair JK, Langer R, Anderson DG. Sequence-Defined Oligomers from Hydroxyproline Building Blocks for Parallel Synthesis Applications. Angew Chem Int Ed Engl. 2016 Aug 08; 55(33):9529-33. PMID: 27365192.
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  88. Farah S, Anderson DG, Langer R. Physical and mechanical properties of P