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Synho Do, Ph.D.

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Ruth L. Kirschstein National Research Service Award, T32


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chua M, Kim D, Choi J, Lee NG, Deshpande V, Schwab J, Lev MH, Gonzalez RG, Gee MS, Do S. Tackling prediction uncertainty in machine learning for healthcare. Nat Biomed Eng. 2022 Dec 29. PMID: 36581695.
    Citations:    Fields:    
  2. Chung J, Kim D, Choi J, Yune S, Song K, Kim S, Chua M, Succi MD, Conklin J, Longo MGF, Ackman JB, Petranovic M, Lev MH, Do S. Prediction of oxygen requirement in patients with COVID-19 using a pre-trained chest radiograph xAI model: efficient development of auditable risk prediction models via a fine-tuning approach. Sci Rep. 2022 12 07; 12(1):21164. PMID: 36476724; PMCID: PMC9729627.
    Citations:    Fields:    Translation:HumansPHPublic Health
  3. Kim D, Chung J, Choi J, Succi MD, Conklin J, Longo MGF, Ackman JB, Little BP, Petranovic M, Kalra MK, Lev MH, Do S. Accurate auto-labeling of chest X-ray images based on quantitative similarity to an explainable AI model. Nat Commun. 2022 04 06; 13(1):1867. PMID: 35388010; PMCID: PMC8986787.
    Citations:    Fields:    Translation:Humans
  4. Choi J, Jeon S, Kim D, Chua M, Do S. A scalable artificial intelligence platform that automatically finds copy number variations (CNVs) in journal articles and transforms them into a database: CNV extraction, transformation, and loading AI (CNV-ETLAI). Comput Biol Med. 2022 05; 144:105332. PMID: 35240378.
    Citations:    Fields:    Translation:Humans
  5. Do S, Song KD, Chung JW. Basics of Deep Learning: A Radiologist's Guide to Understanding Published Radiology Articles on Deep Learning. Korean J Radiol. 2020 01; 21(1):33-41. PMID: 31920027.
    Citations: 21     Fields:    Translation:Humans
  6. Sim Y, Chung MJ, Kotter E, Yune S, Kim M, Do S, Han K, Kim H, Yang S, Lee DJ, Choi BW. Deep Convolutional Neural Network-based Software Improves Radiologist Detection of Malignant Lung Nodules on Chest Radiographs. Radiology. 2020 01; 294(1):199-209. PMID: 31714194.
    Citations: 44     Fields:    Translation:Humans
  7. Lee H, Huang C, Yune S, Tajmir SH, Kim M, Do S. Machine Friendly Machine Learning: Interpretation of Computed Tomography Without Image Reconstruction. Sci Rep. 2019 10 29; 9(1):15540. PMID: 31664075.
    Citations: 6     Fields:    
  8. Yune S, Lee H, Kim M, Tajmir SH, Gee MS, Do S. Beyond Human Perception: Sexual Dimorphism in Hand and Wrist Radiographs Is Discernible by a Deep Learning Model. J Digit Imaging. 2019 08; 32(4):665-671. PMID: 30478479.
    Citations: 4     Fields:    Translation:Humans
  9. Parakh A, Lee H, Lee JH, Eisner BH, Sahani DV, Do S. Urinary Stone Detection on CT Images Using Deep Convolutional Neural Networks: Evaluation of Model Performance and Generalization. Radiol Artif Intell. 2019 Jul; 1(4):e180066. PMID: 33937795; PMCID: PMC8017404.
    Citations: 4     
  10. Lee H, Yune S, Mansouri M, Kim M, Tajmir SH, Guerrier CE, Ebert SA, Pomerantz SR, Romero JM, Kamalian S, Gonzalez RG, Lev MH, Do S. An explainable deep-learning algorithm for the detection of acute intracranial haemorrhage from small datasets. Nat Biomed Eng. 2019 03; 3(3):173-182. PMID: 30948806.
    Citations: 64     Fields:    
  11. Tajmir SH, Lee H, Shailam R, Gale HI, Nguyen JC, Westra SJ, Lim R, Yune S, Gee MS, Do S. Artificial intelligence-assisted interpretation of bone age radiographs improves accuracy and decreases variability. Skeletal Radiol. 2019 Feb; 48(2):275-283. PMID: 30069585.
    Citations: 27     Fields:    Translation:Humans
  12. Lee H, Mansouri M, Tajmir S, Lev MH, Do S. A Deep-Learning System for Fully-Automated Peripherally Inserted Central Catheter (PICC) Tip Detection. J Digit Imaging. 2018 08; 31(4):393-402. PMID: 28983851.
    Citations: 9     Fields:    Translation:Humans
  13. Choy G, Khalilzadeh O, Michalski M, Do S, Samir AE, Pianykh OS, Geis JR, Pandharipande PV, Brink JA, Dreyer KJ. Current Applications and Future Impact of Machine Learning in Radiology. Radiology. 2018 Aug; 288(2):318-328. PMID: 29944078; PMCID: PMC6542626.
    Citations: 153     Fields:    Translation:Humans
  14. McCarthy CJ, Yu AYC, Do S, Dawson SL, Uppot RN. Interventional Radiology Training Using a Dynamic Medical Immersive Training Environment (DynaMITE). J Am Coll Radiol. 2018 05; 15(5):789-793. PMID: 29548790.
    Citations: 3     Fields:    Translation:Humans
  15. Thrall JH, Li X, Li Q, Cruz C, Do S, Dreyer K, Brink J. Artificial Intelligence and Machine Learning in Radiology: Opportunities, Challenges, Pitfalls, and Criteria for Success. J Am Coll Radiol. 2018 03; 15(3 Pt B):504-508. PMID: 29402533.
    Citations: 91     Fields:    Translation:Humans
  16. Fuchs G, Chretien YR, Mario J, Do S, Eikermann M, Liu B, Yang K, Fintelmann FJ. Quantifying the effect of slice thickness, intravenous contrast and tube current on muscle segmentation: Implications for body composition analysis. Eur Radiol. 2018 Jun; 28(6):2455-2463. PMID: 29318425.
    Citations: 16     Fields:    Translation:Humans
  17. Lee H, Troschel FM, Tajmir S, Fuchs G, Mario J, Fintelmann FJ, Do S. Pixel-Level Deep Segmentation: Artificial Intelligence Quantifies Muscle on Computed Tomography for Body Morphometric Analysis. J Digit Imaging. 2017 Aug; 30(4):487-498. PMID: 28653123.
    Citations: 44     Fields:    Translation:Humans
  18. Lee H, Tajmir S, Lee J, Zissen M, Yeshiwas BA, Alkasab TK, Choy G, Do S. Fully Automated Deep Learning System for Bone Age Assessment. J Digit Imaging. 2017 Aug; 30(4):427-441. PMID: 28275919.
    Citations: 83     Fields:    Translation:Humans
  19. Puchner SB, Ferencik M, Maehara A, Stolzmann P, Ma S, Do S, Kauczor HU, Mintz GS, Hoffmann U, Schlett CL. Iterative Image Reconstruction Improves the Accuracy of Automated Plaque Burden Assessment in Coronary CT Angiography: A Comparison With Intravascular Ultrasound. AJR Am J Roentgenol. 2017 Apr; 208(4):777-784. PMID: 28177655.
    Citations: 2     Fields:    Translation:Humans
  20. Khawaja RDA, Singh S, Blake M, Harisinghani M, Choy G, Karaosmanoglu A, Padole A, Do S, Brown K, Thompson R, Morton T, Raihani N, Koehler T, Kalra MK. Corrigendum to "Ultra-low dose abdominal MDCT: Using a knowledge-based Iterative Model Reconstruction technique for substantial dose reduction in a prospective clinical study" [Eur. J. Radiol. 84 (2015) 2-10]. Eur J Radiol. 2016 Jan; 85(1):310. PMID: 28676321.
    Citations:    Fields:    
  21. Khawaja RD, Singh S, Blake M, Harisinghani M, Choy G, Karaosmanoglu A, Karosmanoglu A, Padole A, Pourjabbar S, Do S, Kalra MK. Ultralow-Dose Abdominal Computed Tomography: Comparison of 2 Iterative Reconstruction Techniques in a Prospective Clinical Study. J Comput Assist Tomogr. 2015 Jul-Aug; 39(4):489-98. PMID: 26182223.
    Citations: 7     Fields:    Translation:Humans
  22. Padole A, Singh S, Lira D, Blake MA, Pourjabbar S, Khawaja RD, Choy G, Saini S, Do S, Kalra MK. Assessment of Filtered Back Projection, Adaptive Statistical, and Model-Based Iterative Reconstruction for Reduced Dose Abdominal Computed Tomography. J Comput Assist Tomogr. 2015 Jul-Aug; 39(4):462-7. PMID: 25734468.
    Citations: 9     Fields:    Translation:Humans
  23. Do S, Karl WC, Singh S, Kalra M, Brady T, Shin E, Pien H. High fidelity system modeling for high quality image reconstruction in clinical CT. PLoS One. 2014; 9(11):e111625. PMID: 25390888.
    Citations: 2     Fields:    Translation:Humans
  24. Khawaja RDA, Singh S, Blake M, Harisinghani M, Choy G, Karosmangulu A, Padole A, Do S, Brown K, Thompson R, Morton T, Raihani N, Koehler T, Kalra MK. Ultra-low dose abdominal MDCT: using a knowledge-based Iterative Model Reconstruction technique for substantial dose reduction in a prospective clinical study. Eur J Radiol. 2015 Jan; 84(1):2-10. PMID: 25458225.
    Citations: 17     Fields:    Translation:Humans
  25. Padole A, Singh S, Ackman JB, Wu C, Do S, Pourjabbar S, Khawaja RD, Otrakji A, Digumarthy S, Shepard JA, Kalra M. Submillisievert chest CT with filtered back projection and iterative reconstruction techniques. AJR Am J Roentgenol. 2014 Oct; 203(4):772-81. PMID: 25247943.
    Citations: 14     Fields:    Translation:Humans
  26. Khawaja RD, Singh S, Lira D, Bippus R, Do S, Padole A, Pourjabbar S, Koehler T, Shepard JA, Kalra MK. Role of compressive sensing technique in dose reduction for chest computed tomography: a prospective blinded clinical study. J Comput Assist Tomogr. 2014 Sep-Oct; 38(5):760-7. PMID: 24834892.
    Citations: 2     Fields:    Translation:Humans
  27. Khawaja RD, Singh S, Gilman M, Sharma A, Do S, Pourjabbar S, Padole A, Lira D, Brown K, Shepard JA, Kalra MK. Computed tomography (CT) of the chest at less than 1 mSv: an ongoing prospective clinical trial of chest CT at submillisievert radiation doses with iterative model image reconstruction and iDose4 technique. J Comput Assist Tomogr. 2014 Jul-Aug; 38(4):613-9. PMID: 24651746.
    Citations: 18     Fields:    Translation:Humans
  28. Pourjabbar S, Singh S, Kulkarni N, Muse V, Digumarthy SR, Khawaja RD, Padole A, Do S, Kalra MK. Dose reduction for chest CT: comparison of two iterative reconstruction techniques. Acta Radiol. 2015 Jun; 56(6):688-95. PMID: 24948790.
    Citations: 9     Fields:    Translation:Humans
  29. Pourjabbar S, Singh S, Singh AK, Johnston RP, Shenoy-Bhangle AS, Do S, Padole A, Blake MA, Persson A, Kalra MK. Preliminary results: prospective clinical study to assess image-based iterative reconstruction for abdominal computed tomography acquired at 2 radiation dose levels. J Comput Assist Tomogr. 2014 Jan-Feb; 38(1):117-22. PMID: 24424560.
    Citations: 4     Fields:    Translation:Humans
  30. Liew G, Ali N, Do S, Petranovic M, Cury R, Brady T, Hoffmann U, Ghoshhajra B. A novel analysis algorithm for potential quantitative assessment of myocardial computed tomography perfusion. Acad Radiol. 2013 Oct; 20(10):1301-5. PMID: 24029063.
    Citations: 1     Fields:    Translation:Humans
  31. Ando M, Sunaguchi N, Wu Y, Do S, Sung Y, Louissaint A, Yuasa T, Ichihara S, Gupta R. Crystal analyser-based X-ray phase contrast imaging in the dark field: implementation and evaluation using excised tissue specimens. Eur Radiol. 2014 Feb; 24(2):423-33. PMID: 24048725.
    Citations: 5     Fields:    Translation:Humans
  32. Schlett CL, Maurovich-Horvat P, Ferencik M, Alkadhi H, Stolzmann P, Scheffel H, Seifarth H, Nakano M, Do S, Vorpahl M, Kauczor HU, Bamberg F, Tearney GJ, Virmani R, Hoffmann U. Histogram analysis of lipid-core plaques in coronary computed tomographic angiography: ex vivo validation against histology. Invest Radiol. 2013 Sep; 48(9):646-53. PMID: 23614976.
    Citations: 22     Fields:    Translation:Humans
  33. Puchner SB, Ferencik M, Karolyi M, Do S, Maurovich-Horvat P, Kauczor HU, Hoffmann U, Schlett CL. The effect of iterative image reconstruction algorithms on the feasibility of automated plaque assessment in coronary CT angiography. Int J Cardiovasc Imaging. 2013 Dec; 29(8):1879-88. PMID: 23990390.
    Citations: 6     Fields:    Translation:Humans
  34. Kalra MK, Woisetschläger M, Dahlström N, Singh S, Digumarthy S, Do S, Pien H, Quick P, Schmidt B, Sedlmair M, Shepard JA, Persson A. Sinogram-affirmed iterative reconstruction of low-dose chest CT: effect on image quality and radiation dose. AJR Am J Roentgenol. 2013 Aug; 201(2):W235-44. PMID: 23883238.
    Citations: 16     Fields:    Translation:Humans
  35. Schlett CL, Ferencik M, Celeng C, Maurovich-Horvat P, Scheffel H, Stolzmann P, Do S, Kauczor HU, Alkadhi H, Bamberg F, Hoffmann U. How to assess non-calcified plaque in CT angiography: delineation methods affect diagnostic accuracy of low-attenuation plaque by CT for lipid-core plaque in histology. Eur Heart J Cardiovasc Imaging. 2013 Nov; 14(11):1099-105. PMID: 23671211.
    Citations: 15     Fields:    Translation:Humans
  36. Näppi JJ, Do S, Yoshida H. Computer-Aided Detection of Colorectal Lesions with Super-Resolution CT Colonography: Pilot Evaluation. Abdom Imaging (2013). 2013; 8198:73-80. PMID: 25580475; PMCID: PMC4287197.
  37. Do S, Salvaggio K, Gupta S, Kalra M, Ali NU, Pien H. Automated quantification of pneumothorax in CT. Comput Math Methods Med. 2012; 2012:736320. PMID: 23082091.
    Citations: 6     Fields:    Translation:Humans
  38. Ghoshhajra BB, Engel LC, Major GP, Goehler A, Techasith T, Verdini D, Do S, Liu B, Li X, Sala M, Kim MS, Blankstein R, Prakash P, Sidhu MS, Corsini E, Banerji D, Wu D, Abbara S, Truong Q, Brady TJ, Hoffmann U, Kalra M. Evolution of coronary computed tomography radiation dose reduction at a tertiary referral center. Am J Med. 2012 Aug; 125(8):764-72. PMID: 22703931; PMCID: PMC6849692.
    Citations: 21     Fields:    Translation:HumansPHPublic Health
  39. Singh S, Kalra MK, Do S, Thibault JB, Pien H, O'Connor OJ, Connor OO, Blake MA. Comparison of hybrid and pure iterative reconstruction techniques with conventional filtered back projection: dose reduction potential in the abdomen. J Comput Assist Tomogr. 2012 May-Jun; 36(3):347-53. PMID: 22592622.
    Citations: 45     Fields:    Translation:Humans
  40. Scheffel H, Stolzmann P, Schlett CL, Engel LC, Major GP, Károlyi M, Do S, Maurovich-Horvat P, Hoffmann U. Coronary artery plaques: cardiac CT with model-based and adaptive-statistical iterative reconstruction technique. Eur J Radiol. 2012 Mar; 81(3):e363-9. PMID: 22197733.
    Citations: 40     Fields:    Translation:Humans
  41. Do S, Karl WC, Liang Z, Kalra M, Brady TJ, Pien HH. A decomposition-based CT reconstruction formulation for reducing blooming artifacts. Phys Med Biol. 2011 Nov 21; 56(22):7109-25. PMID: 22025109.
    Citations: 9     Fields:    Translation:Humans
  42. Synho Do; Sarabjeet Singh; Mannudeep K. Kalra; W. Clem Karl; Thomas J. Brady; Homer Pien. Proceeding of SPIE. High-order noise analysis for low dose iterative image reconstruction methods: ASIR, IRIS, and MBAI. 2011; 7961.
  43. Singh S, Kalra MK, Hsieh J, Licato PE, Do S, Pien HH, Blake MA. Abdominal CT: comparison of adaptive statistical iterative and filtered back projection reconstruction techniques. Radiology. 2010 Nov; 257(2):373-83. PMID: 20829535.
    Citations: 131     Fields:    Translation:Humans
  44. Prakash P, Kalra MK, Ackman JB, Digumarthy SR, Hsieh J, Do S, Shepard JA, Gilman MD. Diffuse lung disease: CT of the chest with adaptive statistical iterative reconstruction technique. Radiology. 2010 Jul; 256(1):261-9. PMID: 20574099.
    Citations: 51     Fields:    Translation:Humans
  45. He L, Orten B, Do S, Karl WC, Kambadakone A, Sahani DV, Pien H. A spatio-temporal deconvolution method to improve perfusion CT quantification. IEEE Trans Med Imaging. 2010 May; 29(5):1182-91. PMID: 20378468.
    Citations: 9     Fields:    
  46. Synho Do; W. Clem Karl; Mannudeep K. Kalra; Thomas J. Brady; Homer Pien. Clinical low dose CT image reconstruction using high-order total variation techniques. 2010.
  47. Synho Do; Mannudeep K. Kalra; Zhuangli Liang; W. Clem. Karl; Thomas J. Brady; Homer Pien. Noise properties of iterative reconstruction techniques in low-dose CT scans. 2009.
  48. Synho Do; Zhuangli Liang; William Clem Karl; Thomas Brady; Homer Pien. A projection-driven pre-correction technique for iterative reconstruction of helical cone-beam cardiac CT images. 2008.
  49. Jeong JW, Shin DC, Do SH, Blanco C, Klipfel NE, Holmes DR, Hovanessian-Larsen LJ, Marmarelis VZ. Differentiation of cancerous lesions in excised human breast specimens using multiband attenuation profiles from ultrasonic transmission tomography. J Ultrasound Med. 2008 Mar; 27(3):435-51. PMID: 18314522.
    Citations: 6     Fields:    Translation:Humans
  50. Jeong JW, Shin DC, Do S, Marmarelis VZ. Segmentation methodology for automated classification and differentiation of soft tissues in multiband images of high-resolution ultrasonic transmission tomography. IEEE Trans Med Imaging. 2006 Aug; 25(8):1068-78. PMID: 16894999.
    Citations: 1     Fields:    Translation:Animals
  51. Jeong JW, Kim TS, Shin DC, Do S, Singh M, Marmarelis VZ. Soft tissue differentiation using multiband signatures of high resolution ultrasonic transmission tomography. IEEE Trans Med Imaging. 2005 Mar; 24(3):399-408. PMID: 15754990.
    Citations: 5     Fields:    Translation:HumansAnimals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.